Black Cohosh

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18 Diseases Researched for Black Cohosh

Name	AC	CK
Menopausal Syndrome	4	32
Hot Flash	3	21
Osteoporosis	1	10
Postmenopausal Disorders	1	10
Postmenopausal Disorders: Insomnia	1	10
Quality of Life: Poor	1	10
Breast Cancer	6	6
Estrogen Deficiency	2	4
Prostate Cancer	3	3
Abdominal Obesity (Midsection Fat)	1	2
Aging	1	2
Bone Diseases	1	2
Osteoporosis: Male	1	2
Overweight	1	2
Oxidative Stress	1	2
Breast Cancer: Estrogen	1	1
HIV Infections	1	1
Multiple Myeloma	1	1

12 Pharmacological Actions Researched for Black Cohosh

Name	AC	CK
Antiproliferative	6	6
Antioxidants	2	3
Anti-Inflammatory Agents	1	2
Apoptotic	2	2
Cell cycle arrest	2	2
NF-kappaB Inhibitor	1	2
Osteoprotective	1	2
Selective Estrogen Receptor Modulators	1	2
Angiogenesis Inhibitors	1	1
Anti-HIV Agents	1	1
Chemopreventive	1	1
Cytotoxic	1	1

Research Articles 26
Cumulative Knowledge Score 42
Overall Research Rating GOOD

View the Evidence:
26 Abstracts with Black Cohosh Research

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[+]

A black cohosh extract is equipotent to conjugated estrogens in reducing menopausal symptoms and bone markers, without adverse effects. Mar 14, 2003

Click here to read the entire abstract

Pubmed Data : Maturitas. 2003 Mar 14;44 Suppl 1:S67-77. PMID: 12609561

Article Published Date : Mar 14, 2003

Study Type : Human Study

Additional Links

Substances : Black Cohosh

Diseases : Menopausal Syndrome, Osteoporosis

Additional Keywords : Superiority of Natural Substances versus Drugs

[+]

A comparative study on the effect of black cohosh and evening primrose oil on menopausal hot flashes.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Educ Health Promot. 2018 ;7:36. Epub 2018 Mar 1. PMID: 29619387

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Substances : Black Cohosh, Evening Primrose Oil

Diseases : Hot Flash

[+]

Black cohosh compares favorably to fluoxetine in the treatment of postmenopausal symptoms.Feb 28, 2007

Click here to read the entire abstract

Pubmed Data : Adv Ther. 2007 Mar-Apr;24(2):448-61. PMID: 17565936

Article Published Date : Feb 28, 2007

Study Type : Human Study

Additional Links

Substances : Black Cohosh

Diseases : Hot Flash, Menopausal Syndrome

Additional Keywords : Natural Substances Versus Drugs, Plant Extracts, Superiority of Natural Substances versus Drugs

Problem Substances : Fluoxetine (trade name Prozac)

[+]

Black cohosh effectively improved sleep and might be a safe measure in managing menopausal sleep disturbance.Dec 31, 2014

Click here to read the entire abstract

Pubmed Data : Climacteric. 2015 ;18(4):559-67. Epub 2015 May 22. PMID: 26000551

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : Black Cohosh

Diseases : Postmenopausal Disorders: Insomnia

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Black Cohosh improves quality of life in postmenopausal women with elevated body weight. Jan 01, 2009

Click here to read the entire abstract

Pubmed Data : Gynecol Endocrinol. 2009 Jan;25(1):21-6. PMID: 19165659

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Substances : Black Cohosh

Diseases : Postmenopausal Disorders, Quality of Life: Poor

[+]

Cimicifuga Racemosa may be effective in reducing menopausal symptoms.Nov 30, 2021

Click here to read the entire abstract

Pubmed Data : Gynecol Endocrinol. 2021 Dec ;37(12):1132-1137. Epub 2021 Sep 3. PMID: 34477029

Article Published Date : Nov 30, 2021

Study Type : Human Study

Additional Links

Substances : Black Cohosh

Diseases : Menopausal Syndrome

[+]

Black cohosh (Cimicfuga racemosa) has anti-osteoporotic effects in castrated male rats, without profoundly effecting prostate. Jun 16, 2005

Click here to read the entire abstract

Pubmed Data : Maturitas. 2005 Jun 16;51(2):177-86. PMID: 15917159

Article Published Date : Jun 16, 2005

Study Type : Animal Study

Additional Links

Substances : Black Cohosh

Diseases : Osteoporosis: Male

Additional Keywords : Superiority of Natural Substances versus Drugs

[+]

Black cohosh ameliorates metabolic disorders in female ovariectomized rats.May 31, 2016

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Pubmed Data : Rejuvenation Res. 2016 Jun ;19(3):204-14. Epub 2016 Feb 1. PMID: 26414761

Article Published Date : May 31, 2016

Study Type : Animal Study

Additional Links

Substances : Black Cohosh

Diseases : Menopausal Syndrome

Additional Keywords : Ovariectomy-Induced Changes

[+]

Black cohosh extract has a beneficial effect on body weight, intra-abdominal fat accumulation in ovariectomized rats. Jul 01, 2008

Click here to read the entire abstract

Pubmed Data : Maturitas. 2008 Jul-Aug;60(3-4):209-15. Epub 2008 Aug 8. PMID: 18691839

Article Published Date : Jul 01, 2008

Study Type : Animal Study

Additional Links

Substances : Black Cohosh

Diseases : Abdominal Obesity (Midsection Fat), Overweight

[+]

Black cohosh is an effective alternative to estradiol-17beta due to its selective estrogen receptor modulator activity. Oct 01, 2003

Click here to read the entire abstract

Pubmed Data : Eur J Endocrinol. 2003 Oct;149(4):351-62. PMID: 14514351

Article Published Date : Oct 01, 2003

Study Type : Animal Study

Additional Links

Substances : Black Cohosh

Diseases : Estrogen Deficiency

Pharmacological Actions : Selective Estrogen Receptor Modulators

Additional Keywords : Superiority of Natural Substances versus Drugs

[+]

Black Cohosh may be an ideal Selective Estrogen Receptor Modulator (SERM) alternative to hormone replacement therapy. Sep 01, 2008

Click here to read the entire abstract

Pubmed Data : Maturitas. 2008 Sep-Oct;61(1-2):159-70. PMID: 19434888

Article Published Date : Sep 01, 2008

Study Type : Animal Study

Additional Links

Substances : Black Cohosh

Diseases : Estrogen Deficiency

Additional Keywords : Selective Estrogen Receptor Modulator (SERM), Superiority of Natural Substances versus Drugs

[+]

Cimicifuga racemosa extract Ze 450 re-balances energy metabolism and promotes longevity.Sep 07, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxidants (Basel). 2021 Sep 8 ;10(9). Epub 2021 Sep 8. PMID: 34573064

Article Published Date : Sep 07, 2021

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Black Cohosh

Diseases : Aging, Oxidative Stress

Pharmacological Actions : Antioxidants

[+]

Cimifugin suppresses NF-κB signaling to prevent osteoclastogenesis and periprosthetic osteolysis.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2021 ;12:724256. Epub 2021 Sep 29. PMID: 34658863

Article Published Date : Dec 31, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Black Cohosh

Diseases : Bone Diseases

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective

[+]

Black cohosh contains a compound Actein which exhibits anti-HIV activity. Mar 08, 2004

Click here to read the entire abstract

Pubmed Data : Bioorg Med Chem Lett. 2004 Mar 8;14(5):1329-32. PMID: 14980692

Article Published Date : Mar 08, 2004

Study Type : In Vitro Study

Additional Links

Substances : Black Cohosh

Diseases : HIV Infections

Pharmacological Actions : Anti-HIV Agents

Additional Keywords : Plant Extracts

[+]

Black cohosh could be considered a candidate co-treatment agent of estrogen-dependent tumors.May 24, 2016

Click here to read the entire abstract

Pubmed Data : Gynecol Endocrinol. 2016 May 25:1-4. Epub 2016 May 25. PMID: 27223250

Article Published Date : May 24, 2016

Study Type : In Vitro Study

Additional Links

Substances : Black Cohosh

Diseases : Breast Cancer: Estrogen

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Black Cohosh exhibits anti-cancer effect in estrogen receptor positive and negative human breast cancer cells. Mar 01, 2004

Click here to read the entire abstract

Pubmed Data : Breast Cancer Res Treat. 2004 Mar;84(2):151-60. PMID: 14999145

Article Published Date : Mar 01, 2004

Study Type : In Vitro Study

Additional Links

Substances : Black Cohosh

Diseases : Breast Cancer

[+]

Black Cohosh extract inhibits the development and growth of prostate tumors. Mar 01, 2011

Click here to read the entire abstract

Pubmed Data : J Pineal Res. 2011 Mar;50(2):110-23. Epub 2010 Nov 15. PMID: 16773536

Article Published Date : Mar 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Black Cohosh

Diseases : Prostate Cancer

[+]

Black cohosh has a growth inhibitory activity against human breast cancer cells - Article 2. Feb 01, 2004

Click here to read the entire abstract

Pubmed Data : Breast Cancer Res Treat. 2004 Feb;83(3):221-31. PMID: 14758092

Article Published Date : Feb 01, 2004

Study Type : In Vitro Study

Additional Links

Substances : Black Cohosh

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative , Cell cycle arrest

Additional Keywords : Plant Extracts

[+]

Black cohosh has a growth inhibitory activity against human breast cancer cells. Jun 01, 2008

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2008 Jun;15(6-7):504-11. Epub 2007 Nov 5. PMID: 17980565

Article Published Date : Jun 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Black Cohosh

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative

Additional Keywords : Plant Extracts

[+]

Black cohosh inhibits hormone responsive and hormone independent prostate cancer cells. Jan 01, 2005

Click here to read the entire abstract

Pubmed Data : Anticancer Res. 2005 Jan-Feb;25(1A):139-47. PMID: 15816531

Article Published Date : Jan 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Black Cohosh

Diseases : Prostate Cancer

[+]

Black cohosh potentiates the antiproliferative effects of chemotherapy agents on human breast cancer cells. Oct 01, 2006

Click here to read the entire abstract

Pubmed Data : Planta Med. 2006 Oct;72(13):1200-6. Epub 2006 Sep 20. PMID: 16988912

Article Published Date : Oct 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Black Cohosh

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative , Cell cycle arrest

Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies

[+]

Black Cohosh reduces hot flash symptoms in women. Apr 01, 2008

Click here to read the entire abstract

Pubmed Data : Ginekol Pol. 2008 Apr;79(4):287-96. PMID: 18592868

Article Published Date : Apr 01, 2008

Study Type : Review

Additional Links

Substances : Black Cohosh

Diseases : Hot Flash

[+]

Medicinal herbs used in traditional management of breast cancer.Aug 13, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Medicines (Basel). 2020 Aug 14 ;7(8). Epub 2020 Aug 14. PMID: 32823812

Article Published Date : Aug 13, 2020

Study Type : Review

Additional Links

Substances : Black Cohosh, Burdock, Echinacea, Flaxseed, Garlic, Ginseng, Green Tea, Nigella sativa (aka Black Seed), Turmeric

Diseases : Breast Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Apoptotic

[+]

Petasiphenone, a phenol isolated from Black Cohosh, suppresses prostate cancer cell growth. Feb 01, 2007

Click here to read the entire abstract

Pubmed Data : Planta Med. 2007 Feb;73(2):184-7. Epub 2007 Feb 13. PMID: 17295185

Article Published Date : Feb 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Black Cohosh

Diseases : Prostate Cancer

[+]

Structure-guided identification of black cohosh triterpenoids with in vitro activity against multiple myeloma.Feb 10, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2020 Feb 11 ;25(4). Epub 2020 Feb 11. PMID: 32053921

Article Published Date : Feb 10, 2020

Study Type : In Vitro Study

Additional Links

Substances : Black Cohosh

Diseases : Multiple Myeloma

Pharmacological Actions : Cytotoxic

[+]

This reviews natural plants as breast cancer preventatives or use in treatments. Apr 30, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Saudi Pharm J. 2016 May ;24(3):233-40. Epub 2016 May 5. PMID: 27275107

Article Published Date : Apr 30, 2016

Study Type : Review

Additional Links

Substances : Ashwagandha, Black Cohosh, Burdock, Echinacea, Flavonoids, Flaxseed, Garlic, Ginseng, Polyphenols, Turmeric

Diseases : Breast Cancer

Pharmacological Actions : Antioxidants, Antiproliferative , Chemopreventive

Research Articles 26
Cumulative Knowledge Score 42
Overall Research Rating GOOD

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Black Cohosh Better Than Prozac for Menopause

Written by GreenMedInfo Research Group

Black Cohosh Better Than Prozac for Menopause Do you feel fear or worry regarding the onset of menopause, either for yourself or someone you love? Before you take medications with serious risks, learn about the incredible results of black cohosh

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 26 Abstracts with Black Cohosh Research

Limited to Members Only

Currently Available Sorting Options

A black cohosh extract is equipotent to conjugated estrogens in reducing menopausal symptoms and bone markers, without adverse effects. Mar 14, 2003

A comparative study on the effect of black cohosh and evening primrose oil on menopausal hot flashes.Dec 31, 2017

Black cohosh compares favorably to fluoxetine in the treatment of postmenopausal symptoms.Feb 28, 2007

Black cohosh effectively improved sleep and might be a safe measure in managing menopausal sleep disturbance.Dec 31, 2014

Black Cohosh improves quality of life in postmenopausal women with elevated body weight. Jan 01, 2009

Cimicifuga Racemosa may be effective in reducing menopausal symptoms.Nov 30, 2021

Black cohosh (Cimicfuga racemosa) has anti-osteoporotic effects in castrated male rats, without profoundly effecting prostate. Jun 16, 2005

Black cohosh ameliorates metabolic disorders in female ovariectomized rats.May 31, 2016

Black cohosh extract has a beneficial effect on body weight, intra-abdominal fat accumulation in ovariectomized rats. Jul 01, 2008

Black cohosh is an effective alternative to estradiol-17beta due to its selective estrogen receptor modulator activity. Oct 01, 2003

Black Cohosh may be an ideal Selective Estrogen Receptor Modulator (SERM) alternative to hormone replacement therapy. Sep 01, 2008

Cimicifuga racemosa extract Ze 450 re-balances energy metabolism and promotes longevity.Sep 07, 2021

Cimifugin suppresses NF-κB signaling to prevent osteoclastogenesis and periprosthetic osteolysis.Dec 31, 2020

Black cohosh contains a compound Actein which exhibits anti-HIV activity. Mar 08, 2004

Black cohosh could be considered a candidate co-treatment agent of estrogen-dependent tumors.May 24, 2016

Black Cohosh exhibits anti-cancer effect in estrogen receptor positive and negative human breast cancer cells. Mar 01, 2004

Black Cohosh extract inhibits the development and growth of prostate tumors. Mar 01, 2011

Black cohosh has a growth inhibitory activity against human breast cancer cells - Article 2. Feb 01, 2004

Black cohosh has a growth inhibitory activity against human breast cancer cells. Jun 01, 2008

Black cohosh inhibits hormone responsive and hormone independent prostate cancer cells. Jan 01, 2005

Black cohosh potentiates the antiproliferative effects of chemotherapy agents on human breast cancer cells. Oct 01, 2006

Black Cohosh reduces hot flash symptoms in women. Apr 01, 2008

Medicinal herbs used in traditional management of breast cancer.Aug 13, 2020

Petasiphenone, a phenol isolated from Black Cohosh, suppresses prostate cancer cell growth. Feb 01, 2007

Structure-guided identification of black cohosh triterpenoids with in vitro activity against multiple myeloma.Feb 10, 2020

This reviews natural plants as breast cancer preventatives or use in treatments. Apr 30, 2016

Black Cohosh Related Articles

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Black Cohosh

View the Evidence:
26 Abstracts with Black Cohosh Research