Buckwheat

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39 Diseases Researched for Buckwheat
NameACCKFocus
Polycystic Ovary Syndrome220Locked
Chronic Venous Insufficency110Locked
Edema110Locked
Hypertension110Locked
Leg Edema110Locked
Metabolic Syndrome X110Locked
Venous Insufficiency 110Locked
Inflammation35Locked
Diabetes Mellitus: Type 224Locked
Oxidative Stress34Locked
Liver Cancer23Locked
Alcoholic Liver Disease12Locked
Allergies12Locked
Brain Injury: Hippocampal Damage12Locked
Cerebral Ischemia12Locked
Chemically-Induced Liver Damage12Locked
Chemotherapy-Induced Toxicity: Cyclophosphamide12Locked
Colon Cancer12Locked
Gastric Cancer22Locked
Gastrointestinal Inflammation12Locked
High Fat Diet12Locked
High Fructose Diet12Locked
Hyperglycemia22Locked
Inflammatory Bowel Diseases12Locked
Insulin Resistance12Locked
Lipid Peroxidation12Locked
Lipopolysaccharide-Induced Toxicity12Locked
Memory Disorders12Locked
Obesity12Locked
Stress12Locked
Acute lymphoblastic leukemia (ALL)11Locked
Appetite Disorders11Locked
Breast Cancer11Locked
High Cholesterol11Locked
Hyperlipidemia11Locked
Lung Cancer11Locked
Triglycerides: Elevated11Locked
Weight Probems: Appetite 11Locked
Wound Healing11Locked
25 Pharmacological Actions Researched for Buckwheat
NameACCKFocus
Antioxidants68Locked
Anti-Inflammatory Agents36Locked
Hypoglycemic Agents46Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor24Locked
Apoptotic23Locked
Hypolipidemic23Locked
Alpha-glucosidase inhibitor 22Locked
Anti-Allergic Agents12Locked
Anti-Apoptotic12Locked
Antiproliferative 22Locked
Bcl-2 protein down-regulation12Locked
Chemoprotective Agents12Locked
Gastrointestinal Agents12Locked
Heme oxygenase-1 up-regulation12Locked
Hepatoprotective12Locked
Histamine Antagonists12Locked
Interleukin-6 Downregulation12Locked
Malondialdehyde Down-regulation12Locked
Neuroprotective Agents12Locked
Nrf2 activation12Locked
Pancreato Protective Agents12Locked
Superoxide Dismutase Up-regulation12Locked
Tumor Suppressor Protein p53 Upregulation12Locked
Alpha-amylase inhibitor11Locked
Protease Inhibitors11Locked

View the Evidence:
41 Abstracts with Buckwheat Research

[+]

Buckwheat herb tea protects against leg edemia in patients with chronic venous insufficiency.Jan 01, 1996

Pubmed Data : Eur J Clin Pharmacol. 1996;50(6):443-7. PMID: 8858269
Article Published Date : Jan 01, 1996
Study Type : Human Study
Additional Links
Substances : Buckwheat, Rutin
Diseases : Chronic Venous Insufficency, Edema, Leg Edema, Venous Insufficiency
Additional Keywords : Plant Extracts
[+]

D-chiro-inositol has a therapeutic effect in lean women with the polycystic ovary syndrome.Nov 01, 2002

Pubmed Data : Endocr Pract. 2002 Nov-Dec;8(6):417-23. PMID: 15251831
Article Published Date : Nov 01, 2002
Study Type : Human Study
Additional Links
Substances : Buckwheat, D-Chiro-Inositol, Inositol
Diseases : Hypertension, Metabolic Syndrome X, Polycystic Ovary Syndrome
[+]

The compound found in buckwheat known as d-chiro-inositol have a therapeutic effect in polycystic ovary syndrome.Apr 29, 1999

Pubmed Data : N Engl J Med. 1999 Apr 29;340(17):1314-20. PMID: 10219066
Article Published Date : Apr 29, 1999
Study Type : Human Study
Additional Links
Substances : Buckwheat, D-Chiro-Inositol, Inositol
Diseases : Polycystic Ovary Syndrome
[+]

Regulation of tartary buckwheat-resistant starch on intestinal microflora in mice fed with high-fat diet.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2020 Jul ;8(7):3243-3251. Epub 2020 May 12. PMID: 32724589
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Buckwheat
Diseases : High Fat Diet
Pharmacological Actions : Gastrointestinal Agents
[+]

Buckwheat and buckwheat enriched products exert an anti-inflammatory effect on the myofibroblasts of colon.Jun 19, 2018

Pubmed Data : Food Funct. 2018 Jun 20 ;9(6):3387-3397. PMID: 29870039
Article Published Date : Jun 19, 2018
Study Type : Animal Study
Additional Links
Substances : Buckwheat
Diseases : Gastrointestinal Inflammation, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Buckwheat flour and its starch prevent age-related cognitive decline.Jun 28, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Jun 29 ;14(13). Epub 2022 Jun 29. PMID: 35807886
Article Published Date : Jun 28, 2022
Study Type : Animal Study
Additional Links
Substances : Buckwheat
Diseases : Aging: Brain , Cognitive Decline/Dysfunction
Pharmacological Actions : Brain-derived neurotrophic factor modulator, Neuroprotective Agents
[+]

Buckwheat grain extract has anti-allergic properties.Jan 01, 2003

Pubmed Data : Int Immunopharmacol. 2003 Jan;3(1):129-36. PMID: 12538043
Article Published Date : Jan 01, 2003
Study Type : Animal Study
Additional Links
Substances : Buckwheat
Diseases : Allergies
Pharmacological Actions : Anti-Allergic Agents, Histamine Antagonists
Additional Keywords : Plant Extracts
[+]

Buckwheat phenolic compounds have in vivo antistress effects against the reactions induced by immobilization in mice.Jul 22, 2009

Pubmed Data : J Agric Food Chem. 2009 Jul 22;57(14):6438-42. PMID: 19601674
Article Published Date : Jul 22, 2009
Study Type : Animal Study
Additional Links
Substances : Buckwheat, Catechin
Diseases : Stress
[+]

Buckwheat polyphenols protective effect against long-lasting impairment of spatial memory associated with hippocampal neuronal damage in rats subjected to repeated cerebral ischemia.Apr 01, 2004

Pubmed Data : J Pharmacol Sci. 2004 Apr;94(4):393-402. PMID: 15107579
Article Published Date : Apr 01, 2004
Study Type : Animal Study
Additional Links
Substances : Buckwheat, Flavonoids, Polyphenols
Diseases : Brain Injury: Hippocampal Damage, Cerebral Ischemia, Memory Disorders
Pharmacological Actions : Neuroprotective Agents
[+]

Buckwheat sprouts have an anti-inflammatory effect in lipopolysaccharide-activated human colon cancer cells and mice.Dec 01, 2008

Pubmed Data : Biosci Biotechnol Biochem. 2008 Dec;72(12):3148-57. Epub 2008 Dec 7. PMID: 19060399
Article Published Date : Dec 01, 2008
Study Type : Animal Study
Additional Links
Substances : Buckwheat, Flavonoids, Sprouts
Diseases : Colon Cancer, Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

Buckwheat-enriched diet alleviates bisphenol A mediated oxidative stress.Oct 31, 2021

Pubmed Data : Food Chem. 2021 Nov 1:131507. Epub 2021 Nov 1. PMID: 34763933
Article Published Date : Oct 31, 2021
Study Type : Animal Study
Additional Links
Substances : Buckwheat
Diseases : Bisphenol Toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants
Problem Substances : Bisphenol A
[+]

D-Chiro-Inositol found in Buckwheat concentrate reduces serum glucose.Dec 03, 2003

Pubmed Data : J Agric Food Chem. 2003 Dec 3;51(25):7287-91. PMID:14640572
Article Published Date : Dec 03, 2003
Study Type : Animal Study
Additional Links
Substances : Buckwheat
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
[+]

Effects of tartary buckwheat protein on gut microbiome and plasma metabolite in rats with high-fat diet.Oct 14, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2021 Oct 15 ;10(10). Epub 2021 Oct 15. PMID: 34681506
Article Published Date : Oct 14, 2021
Study Type : Animal Study
Additional Links
Substances : Buckwheat
Diseases : Fatty Liver, High Fat Diet, Hyperlipidemia
Pharmacological Actions : Hypolipidemic
[+]

Flavonoids derived from buckwheat hull can break advanced glycation end-products and improve diabetic nephropathy.Jun 24, 2021

Pubmed Data : Food Funct. 2021 Jun 25. Epub 2021 Jun 25. PMID: 34169956
Article Published Date : Jun 24, 2021
Study Type : Animal Study
Additional Links
Substances : Buckwheat, Flavonoids
Diseases : Advanced Glycation End products (AGE), Diabetic Nephropathy
Pharmacological Actions : Anti-Glycation Agents
[+]

Probiotic-fermented black tartary buckwheat alleviates hyperlipidemia and gut microbiota dysbiosis in rats fed with a high-fat diet.May 25, 2021

Pubmed Data : Food Funct. 2021 May 26. Epub 2021 May 26. PMID: 34037655
Article Published Date : May 25, 2021
Study Type : Animal Study
Additional Links
Substances : Buckwheat
Diseases : Dysbiosis, High Fat Diet, Hyperlipidemia
Pharmacological Actions : Gastrointestinal Agents, Hypolipidemic
[+]

Stem and leaf of black bitter buckwheat has significant therapeutic effects on reducing blood sugar and blood fat in type 2 diabetic mice.Jan 31, 2019

Pubmed Data : Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2019 Feb ;35(2):140-144. PMID: 31250605
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Buckwheat
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic, Pancreato Protective Agents
[+]

Tartary buckwheat extract alleviates alcohol-induced acute and chronic liver injuries.Dec 31, 2019

Pubmed Data : Am J Transl Res. 2020 ;12(1):70-89. Epub 2020 Jan 15. PMID: 32051738
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Buckwheat
Diseases : Alcoholic Liver Disease, Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Apoptotic, Hepatoprotective
[+]

Tartary buckwheat extract might attenuate obesity-induced inflammation and mitochondrial dysfunction.Mar 17, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Mar 18 ;11(3). Epub 2019 Mar 18. PMID: 30889894
Article Published Date : Mar 17, 2019
Study Type : Animal Study
Additional Links
Substances : Buckwheat
Diseases : Inflammation, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Obesity Agents
[+]

Tartary buckwheat flavonoids ameliorate high fructose-induced insulin resistance and oxidative stress.Jul 16, 2017

Pubmed Data : Food Funct. 2017 Jul 17. Epub 2017 Jul 17. PMID: 28714504
Article Published Date : Jul 16, 2017
Study Type : Animal Study
Additional Links
Substances : Buckwheat, Flavonoids
Diseases : High Fructose Diet, Insulin Resistance
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
Additional Keywords : Antioxidants, Buckwheat, Flavonoids, High Fructose Diet, Insulin Resistance
[+]

Tartary buckwheat flavonoids improve colon lesions and modulate gut microbiota composition.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:4524444. Epub 2022 Aug 16. PMID: 36016679
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Buckwheat, Flavonoids
Diseases : Colon Cancer, Diabetic Complications
Pharmacological Actions : Anti-Inflammatory Agents, Chemopreventive, Gastroprotective, Hypoglycemic Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Tatariside possess notable antitumor effects against HCC and might play a favorable role in drug combination therapy against tumors with protective effect on liver.Jul 14, 2015

Pubmed Data : Phytomedicine. 2015 Jul 15 ;22(7-8):730-6. Epub 2015 May 23. PMID: 26141759
Article Published Date : Jul 14, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Buckwheat
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide, Liver Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Chemoprotective Agents, Tumor Suppressor Protein p53 Upregulation
Problem Substances : Cyclophosphamide
[+]

The effects of buckwheat leaf and flower extracts on antioxidant status in mouse organs.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:6712407. Epub 2018 Jun 14. PMID: 30013721
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Buckwheat
Diseases : Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

These findings suggested that buckwheat and bee pollen extract had the effects of alleviating colitis and immunomodulation.Apr 28, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2022 Apr 29 ;11(9). Epub 2022 Apr 29. PMID: 35564016
Article Published Date : Apr 28, 2022
Study Type : Animal Study
Additional Links
Substances : Bee Pollen, Buckwheat
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-4 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

A novel antidiabetic food produced via solid-state fermentation of tartary buckwheat by L. plantarum TK9 and L. paracasei TK1501.Aug 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Technol Biotechnol. 2018 Sep ;56(3):373-380. PMID: 30510481
Article Published Date : Aug 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Buckwheat, Fermented Foods and Beverages, Lactobacillus paracasei, Lactobacillus plantarum
Diseases : Hyperglycemia
Pharmacological Actions : Alpha-glucosidase inhibitor , Hypoglycemic Agents
[+]

Alternative grains and psuedocereal products may have appetite reducing activity.Nov 01, 2005

Pubmed Data : Br J Nutr. 2005 Nov;94(5):850-8. PMID: 16277791
Article Published Date : Nov 01, 2005
Study Type : Commentary
Additional Links
Substances : Amaranth , Buckwheat, Oats, Quinoa
Diseases : Appetite Disorders, Weight Probems: Appetite
[+]

Antibacterial photodynamic inactivation of fagopyrin F from tartary buckwheat flower against Streptococcus mutans.Jun 07, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2021 Jun 8 ;22(12). Epub 2021 Jun 8. PMID: 34201389
Article Published Date : Jun 07, 2021
Study Type : In Vitro Study
Additional Links
Substances : Buckwheat
Diseases : Steptococcus Mutans Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation, Plant Extracts
[+]

Antioxidant and antidiabetic activity of proanthocyanidins from Fagopyrum dibotrys.Apr 20, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Apr 21 ;26(9). Epub 2021 Apr 21. PMID: 33919259
Article Published Date : Apr 20, 2021
Study Type : In Vitro Study
Additional Links
Substances : Buckwheat
Diseases : Hyperglycemia, Oxidative Stress
Pharmacological Actions : Antioxidants, Hypoglycemic Agents
Additional Keywords : Plant Extracts, Proanthocyanidins
[+]

Appropriate treatment with sodium bicarbonate could improve the healthy benefits of tartary buckwheat sprouts.May 31, 2017

Pubmed Data : Food Chem. 2017 Jun 1 ;224:124-130. Epub 2016 Dec 22. PMID: 28159246
Article Published Date : May 31, 2017
Study Type : Plant Study
Additional Links
Substances : Buckwheat, Sodium Bicarbonate
Pharmacological Actions : Alpha-glucosidase inhibitor , Antioxidants
[+]

Buckwheat and especially buckwheat sprouts have significant antioxidant activity.Jan 09, 2008

Pubmed Data : J Agric Food Chem. 2008 Jan 9;56(1):173-8. Epub 2007 Dec 12. PMID: 18072736
Article Published Date : Jan 09, 2008
Study Type : In Vitro Study
Additional Links
Substances : Buckwheat, Rutin, Sprouts
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Buckwheat has a cytotoxic effect on a number of cancer cell lines.Jun 01, 2007

Pubmed Data : J Med Food. 2007 Jun;10(2):232-8. PMID: 17651057
Article Published Date : Jun 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Buckwheat
Diseases : Breast Cancer, Gastric Cancer, Liver Cancer, Lung Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Plant Extracts
[+]

Buckwheat honey has antioxidant and anti-inflammatory properities which may aid in wound-healing.Jul 01, 2009

Pubmed Data : Br J Pharmacol. 2009 Jul;157(5):844-53. Epub 2009 May 5. PMID: 18494436
Article Published Date : Jul 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Buckwheat, Honey
Diseases : Inflammation, Oxidative Stress, Wound Healing
[+]

Gene expression results showed that the phenolic compounds in Tartary buckwheat sprouts increased with the use of l-Phe and LED lights.Jun 14, 2015

Pubmed Data : Food Chem. 2015 Jun 15 ;177:204-13. Epub 2015 Jan 2. PMID: 25660878
Article Published Date : Jun 14, 2015
Study Type : Plant Study
Additional Links
Substances : Buckwheat, Phenylalyanine
Additional Keywords : Growing Your Own Food, Light-Emitting Diodes (LEDs)
[+]

Health benefits of Buckwheat (Fagopyrum esculentum), potential remedy for diseases, rare to cancer.Dec 23, 2020

Pubmed Data : Infect Disord Drug Targets. 2020 Dec 24. Epub 2020 Dec 24. PMID: 33357186
Article Published Date : Dec 23, 2020
Study Type : Review
Additional Links
Substances : Buckwheat
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Inhibition mechanism of α-glucosidase inhibitors screened from Tartary buckwheat and synergistic effect with acarbose.Sep 14, 2023

Pubmed Data : Food Chem. 2023 Sep 15 ;420:136102. Epub 2023 Apr 7. PMID: 37060666
Article Published Date : Sep 14, 2023
Study Type : In Vitro Study
Additional Links
Substances : Buckwheat
Diseases : Hyperglycemia
Pharmacological Actions : Alpha-glucosidase inhibitor , Hypoglycemic Agents
Additional Keywords : Natural Substance/Drug Synergy
[+]

Lapathoside A isolated from Fagopyrum esculentum induces apoptosis in human pancreatic cancer cells.Jan 31, 2021

Pubmed Data : Anticancer Res. 2021 Feb ;41(2):747-756. PMID: 33517279
Article Published Date : Jan 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Buckwheat
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic
[+]

Nutritional evaluation: Buckwheat.Jul 26, 2006

Pubmed Data : J Agric Food Chem. 2006 Jul 26;54(15):5330-5. PMID: 16848513
Article Published Date : Jul 26, 2006
Study Type : In Vitro Study
Additional Links
Substances : Buckwheat, Catechin , Rutin
[+]

Protease inhibitors from buckwheat seeds are active against human T-acute lymphoblastic leukemia cell lines.May 01, 2004

Pubmed Data : Appl Biochem Biotechnol. 2004 May;117(2):65-74. PMID: 15159551
Article Published Date : May 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Buckwheat
Diseases : Acute lymphoblastic leukemia (ALL)
Pharmacological Actions : Protease Inhibitors
[+]

Sprouting buckwheat triggers a variety of nutritional changes increasing hypocholesterolemic, hypotriglyceridemic, and antioxidative activities.Feb 27, 2008

Pubmed Data : J Agric Food Chem. 2008 Feb 27;56(4):1216-23. Epub 2008 Jan 24. PMID: 18217700
Article Published Date : Feb 27, 2008
Study Type : In Vitro Study
Additional Links
Substances : Buckwheat, Flavonoids, Polyphenols, Quercetin, Rutin, Sprouts, Vitamin C
Diseases : High Cholesterol, Hyperlipidemia, Triglycerides: Elevated
Pharmacological Actions : Antioxidants, Hypolipidemic
Additional Keywords : Plant Extracts
[+]

Suppressive effect of the α-amylase ihibitor albumin from buckwheat.Oct 14, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Oct 15 ;10(10). Epub 2018 Oct 15. PMID: 30326572
Article Published Date : Oct 14, 2018
Study Type : In Vitro Study
Additional Links
Substances : Buckwheat
Diseases : Hyperglycemia
Pharmacological Actions : Alpha-amylase inhibitor, Hypoglycemic Agents
[+]

Tartary buckwheat flavonoids in inhibit the proliferation of MGC80-3 cells. Aug 25, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Aug 26 ;24(17). Epub 2019 Aug 26. PMID: 31454945
Article Published Date : Aug 25, 2019
Study Type : In Vitro Study
Additional Links
Substances : Buckwheat
Diseases : Gastric Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Trace element water improves the antioxidant activity of buckwheat sprouts.Aug 01, 2007

Pubmed Data : Acta Cardiol. 2007 Aug;62(4):381-9. PMID: 17902620
Article Published Date : Aug 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Buckwheat, Sprouts, Trace Minerals
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts

Copyright: yelenayemchuk / 123RF Stock Photo

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