Burdock

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42 Diseases Researched for Burdock
NameACCKFocus
Cancers: Drug Resistant211Locked
Inflammation211Locked
C-Reactive Protein110Locked
Osteoarthritis110Locked
Pancreatic Cancer110Locked
Breast Cancer: Triple Negative 45Locked
Breast Cancer44Locked
Colitis24Locked
Diabetes Mellitus: Type 224Locked
Gastric Ulcer24Locked
Allergies33Locked
Acetaminophen (Tylenol) Toxicity 12Locked
Alcohol Toxicity 12Locked
Animal Diseases: Porcine Circovirus Type 2 (PCV2) 12Locked
Atherosclerosis12Locked
Autoimmune Diseases12Locked
Brain Inflammation 12Locked
Chemotherapy-Induced Toxicity: Mitomycin-C12Locked
DNA damage12Locked
High Fat Diet12Locked
Hyperlipidemia12Locked
Infertility: Male12Locked
Inflammatory Bowel Diseases12Locked
Multiple Sclerosis12Locked
Obesity12Locked
Oxidative Stress22Locked
Bladder Stones11Locked
Cancers: Multi-Drug Resistant11Locked
Candida Albicans11Locked
Colon Cancer11Locked
Dermatitis: Contact11Locked
Dysbiosis11Locked
Escherichia coli Infections11Locked
Foodborne Pathogens: Prevention/Food Preservation11Locked
Kidney Stones11Locked
Klebsiella Infections11Locked
Leukemia11Locked
Mycobacterium tuberculosis11Locked
Prostate Cancer11Locked
Pseudomonas aeruginosa11Locked
Urolithiasis11Locked
Aging Skin10Locked
39 Pharmacological Actions Researched for Burdock
NameACCKFocus
Anti-Inflammatory Agents618Locked
Antioxidants312Locked
Interleukin-6 Downregulation212Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor46Locked
Antiproliferative 45Locked
Anti-Bacterial Agents44Locked
Hepatoprotective24Locked
Immunomodulatory: Th17 downregulation24Locked
Anti-Allergic Agents33Locked
Apoptotic23Locked
Anti-Ulcer Agents12Locked
Anti-metastatic22Locked
Anticholesteremic Agents12Locked
Antimutagenic Agents12Locked
Antiviral Agents12Locked
Bax/Bcl2 ratio: Increase22Locked
Chemopreventive22Locked
Chemotherapeutic12Locked
Cyclooxygenase 2 Inhibitors12Locked
Fertility Agents: Male12Locked
Gastroprotective12Locked
Hypolipidemic12Locked
Immunomodulatory12Locked
Immunosuppressive Agents12Locked
Interleukin-10 downregulation12Locked
Interleukin-4 downregulation22Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor22Locked
NF-kappaB Inhibitor22Locked
Neuroprotective Agents22Locked
STAT3 Inhibitor12Locked
Anti-Apoptotic11Locked
Chemosensitizer11Locked
Histamine down-regulation11Locked
Hypoglycemic Agents11Locked
Interleukin-5 downregulation11Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor11Locked
Multidrug Resistance Gene Modulators11Locked
Prostaglandin PGE2 downregulation11Locked
Superoxide Dismutase Up-regulation11Locked

View the Evidence:
99 Abstracts with Burdock Research

[+]

Anti-acne action of peptides isolated from burdock root-preliminary studies and pilot testing.Apr 26, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Apr 27 ;25(9). Epub 2020 Apr 27. PMID: 32349230
Article Published Date : Apr 26, 2020
Study Type : Human Study
Additional Links
Substances : Burdock
Diseases : Acne
Pharmacological Actions : Anti-Bacterial Agents
[+]

Burdock complex could attenuate H. pylori infection by inhibiting adhesion and subsequent inflammatory response on the gastric epithelial cells.Mar 07, 2018

Pubmed Data : Helicobacter. 2018 Mar 8. Epub 2018 Mar 8. PMID: 29520881
Article Published Date : Mar 07, 2018
Study Type : Human Study
Additional Links
Substances : Burdock
Diseases : Helicobacter Pylori Infection
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Burdock root tea improves inflammatory status and oxidative stress in patients with knee osteoarthritis.Oct 27, 2014

Pubmed Data : Int J Rheum Dis. 2014 Oct 28. Epub 2014 Oct 28. PMID: 25350500
Article Published Date : Oct 27, 2014
Study Type : Human Study
Additional Links
Substances : Burdock
Diseases : C-Reactive Protein, Inflammation, Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation
[+]

Exercise training and burdock root extract independently improve abdominal obesity and sex hormones.Mar 03, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2021 Mar 4 ;11(1):5175. Epub 2021 Mar 4. PMID: 33664334
Article Published Date : Mar 03, 2021
Study Type : Human Study
Additional Links
Substances : Burdock
Diseases : Metabolic Syndrome X, Obesity
Therapeutic Actions : Exercise
Additional Keywords : Anti-Obesity Agents
[+]

Of the 15 patients, 1 showed confirmed partial response and 4 patients had stable disease.Sep 28, 2016

Pubmed Data : Cancer Sci. 2016 Sep 29. Epub 2016 Sep 29. PMID: 27685612
Article Published Date : Sep 28, 2016
Study Type : Human Study
Additional Links
Substances : Burdock
Diseases : Cancers: Drug Resistant, Pancreatic Cancer
Additional Keywords : Plant Extracts
[+]

A. lappa root may have antiinfertility effects by increasing sperm count and, serum gonadotropin and testosterone levels of nondiabetic mice. Feb 28, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Malays J Med Sci. 2015 Mar-Apr;22(2):25-32. PMID: 26023292
Article Published Date : Feb 28, 2015
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Diabetes Mellitus: Type 2, Infertility: Male
Pharmacological Actions : Fertility Agents: Male
Additional Keywords : Plant Extracts
[+]

A Burdock extract was able to reduce intestinal inflammation in an acute TNBS-induced experimental model of colitis in rats.Mar 06, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ethnopharmacol. 2013 Mar 7 ;146(1):300-10. Epub 2013 Jan 10. PMID: 23313393
Article Published Date : Mar 06, 2013
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

A dicaffeoylquinic acid isomer from Arctium lappa has a potent anti-ulcer activity.Mar 31, 2015

Pubmed Data : Talanta. 2015 Apr ;135:50-7. Epub 2014 Dec 10. PMID: 25640125
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Alcohol Toxicity , Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents
Additional Keywords : Plant Extracts
[+]

A herbal preparation suppressed 80 % of DNA strand breaks in the liver, kidney, lung, brain and testicles of mice exposed to mitomycin C.Feb 09, 2015

Pubmed Data : J Nat Med. 2015 Feb 10. Epub 2015 Feb 10. PMID: 25666712
Article Published Date : Feb 09, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Barberry, Burdock, Dandelion
Diseases : Chemotherapy-Induced Toxicity: Mitomycin-C, DNA damage
Pharmacological Actions : Antimutagenic Agents
Additional Keywords : Drug: Mitomycin, Plant Extracts
[+]

A. lappa could protect the liver cells from carbon tetrachloride or acetaminophen-induced liver damages.Dec 31, 1999

Pubmed Data : Am J Chin Med. 2000 ;28(2):163-73. PMID: 10999435
Article Published Date : Dec 31, 1999
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Acetaminophen (Tylenol) Toxicity , Chemically-Induced Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective
Additional Keywords : Plant Extracts
Problem Substances : Acetaminophen, Paracetamol
[+]

Anti-inflammatory activity of alkali-soluble polysaccharides from Arctium lappa L. and its effect on gut microbiota of mice with inflammation.Mar 18, 2020

Pubmed Data : Int J Biol Macromol. 2020 Mar 19 ;154:773-787. Epub 2020 Mar 19. PMID: 32199919
Article Published Date : Mar 18, 2020
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Antidepressive effect of arctiin by attenuating neuroinflammation.Jan 04, 2020

Pubmed Data : ACS Chem Neurosci. 2020 08 5 ;11(15):2214-2230. Epub 2020 Jul 15. PMID: 32609480
Article Published Date : Jan 04, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Burdock
Diseases : Brain Inflammation , Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Aqueous extract of burdock root reduced body weight and cholesterol in rats, possibly by modulating the differential expression of genes.Dec 31, 2016

Pubmed Data : J Int Med Res. 2017 Jan 1:300060517716341. Epub 2017 Jan 1. PMID: 28758851
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : High Fat Diet
Pharmacological Actions : Anticholesteremic Agents, Hypolipidemic
Additional Keywords : Gene Expression Regulation
[+]

Arctigenin ameliorates colitis through down-regulating the differentiation of Th1 and Th17 cells via mTORC1 pathway. Aug 14, 2015

Pubmed Data : Biochem Pharmacol. 2015 Aug 15 ;96(4):323-36. Epub 2015 Jun 11. PMID: 26074264
Article Published Date : Aug 14, 2015
Study Type : Animal Study
Additional Links
Substances : Arctigenin, Burdock
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Arctigenin inhibits STAT3 and exhibits anticancer potential in human triple-negative breast cancerJan 02, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Jan 3 ;8(1):329-344. PMID: 27861147
Article Published Date : Jan 02, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Burdock
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative , Apoptotic, Chemotherapeutic, STAT3 Inhibitor
[+]

Arctigenin may have anti-inflammatory and immunosuppressive properties via inhibiting Th17 cells.Oct 05, 2015

Pubmed Data : Mol Neurobiol. 2015 Oct 6. Epub 2015 Oct 6. PMID: 26440666
Article Published Date : Oct 05, 2015
Study Type : Animal Study
Additional Links
Substances : Arctigenin, Burdock
Diseases : Autoimmune Diseases, Brain Inflammation , Multiple Sclerosis
Pharmacological Actions : Immunomodulatory: Th17 downregulation, Immunosuppressive Agents
[+]

Arctigenin may have the potential to serve as a drug for protection of pigs against the infection of PCV2.May 31, 2016

Pubmed Data : Res Vet Sci. 2016 Jun ;106:159-64. Epub 2015 Oct 26. PMID: 27234554
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Arctigenin, Burdock
Diseases : Animal Diseases: Porcine Circovirus Type 2 (PCV2)
Pharmacological Actions : Antiviral Agents
[+]

Arctigenin-containing burdock sprout extract prevents obesity in association with modulation of the gut microbiot.Dec 31, 2022

Pubmed Data : Biosci Microbiota Food Health. 2023 ;42(1):49-55. Epub 2022 Aug 25. PMID: 36660596
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Burdock, Genipin
Diseases : Obesity
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Anti-Obesity Agents
[+]

Arctii Fructus could be an effective therapeutic for treating or preventing obesity.Dec 06, 2016

Pubmed Data : Food Funct. 2016 Dec 7 ;7(12):5025-5033. PMID: 27882370
Article Published Date : Dec 06, 2016
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Obesity
Additional Keywords : Anti-Obesity Agents, Burdock, obesity, Plant Extracts
[+]

Arctiin prevents LPS-induced acute lung injury via inhibition of PI3K/AKT signaling pathway.Nov 30, 2018

Pubmed Data : Inflammation. 2018 Dec ;41(6):2129-2135. PMID: 30116933
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Arctiin protects against cardiac hypertrophy through inhibiting MAPKs and AKT signaling pathways.Oct 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacol Sci. 2017 Nov ;135(3):97-104. Epub 2017 Aug 10. PMID: 29108833
Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Cardiac Hypertrophy
Pharmacological Actions : Cardioprotective
Additional Keywords : Phytotherapy
[+]

Arctiin protects rat heart against ischemia/reperfusion injury.May 14, 2020

Pubmed Data : Eur J Pharmacol. 2020 May 15 ;875:173053. Epub 2020 Mar 2. PMID: 32135123
Article Published Date : May 14, 2020
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Myocardial Ischemia
Pharmacological Actions : Cardioprotective
[+]

Arctium lappa can prevent most of the hepatic tissue damage caused by acetaminophen overdose in rats.Nov 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Ther Res Clin Exp. 2015 Dec ;77:73-8. Epub 2015 May 27. PMID: 26543508
Article Published Date : Nov 30, 2015
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Acetaminophen (Tylenol) Toxicity
Pharmacological Actions : Hepatoprotective
Problem Substances : Acetaminophen, Paracetamol
[+]

Arctium lappa could be considered a potentially valuable medicinal food for dry age-related macular degeneration.Apr 08, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Apr 9 ;25(7). Epub 2020 Apr 9. PMID: 32283798
Article Published Date : Apr 08, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Burdock
Diseases : Macular Degeneration
Pharmacological Actions : Anti-Apoptotic
[+]

Arctium lappa extract suppresses inflammation and inhibits melanoma progression.Jul 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicines (Basel). 2019 Jul 29 ;6(3). Epub 2019 Jul 29. PMID: 31362372
Article Published Date : Jul 28, 2019
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Melanoma
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
[+]

Arctium lappa has ameliorative effects against cadmium genotoxicity.Dec 31, 2016

Pubmed Data : Pak J Biol Sci. 2017 ;20(6):314-319. PMID: 29023056
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Cadmium Poisoning
Pharmacological Actions : Genoprotective, Renoprotective
[+]

Arctium lappa L. polysaccharide can regulate lipid metabolism in type 2 diabetic rats.Jul 31, 2020

Pubmed Data : Carbohydr Res. 2020 Aug ;494:108055. Epub 2020 Jun 7. PMID: 32535406
Article Published Date : Jul 31, 2020
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Atherosclerosis, Diabetes Mellitus: Type 2
Pharmacological Actions : Hypolipidemic
Additional Keywords : Polysaccharides
[+]

Arctium lappa L. roots protect against cerebral ischemia through inhibiting apoptosis and AMPK/mTOR-mediated autophagy.Feb 20, 2021

Pubmed Data : Phytomedicine. 2021 Feb 21 ;85:153526. Epub 2021 Feb 21. PMID: 33691269
Article Published Date : Feb 20, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Burdock
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Apoptotic, Autophagy Up-regulation, Neuroprotective Agents
[+]

Arctium lappa leaves based on network pharmacology and experimental validation attenuate atherosclerosis.Aug 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 Sep ;153:113503. Epub 2022 Aug 16. PMID: 36076592
Article Published Date : Aug 31, 2022
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Atherosclerosis
Pharmacological Actions : Cardioprotective
[+]

Arctium lappa root extract containing L-arginine prevents TNF-α-induced early atherosclerosis in vitro and in vivo.Mar 20, 2020

Pubmed Data : Nutr Res. 2020 Mar 21 ;77:85-96. Epub 2020 Mar 21. PMID: 32388084
Article Published Date : Mar 20, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Burdock
Diseases : Atherosclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Arctium lappa root extract prevents lead-induced liver injury.Nov 23, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2019 Nov 24 ;8(12). Epub 2019 Nov 24. PMID: 31771282
Article Published Date : Nov 23, 2019
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
Problem Substances : Lead
[+]

Arctium minus crude extract presents antinociceptive effect in a mice acute gout attack model.Aug 10, 2017

Pubmed Data : Inflammopharmacology. 2017 Aug 11. Epub 2017 Aug 11. PMID: 28801728
Article Published Date : Aug 10, 2017
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Allodynia, Gout
Pharmacological Actions : Antinoceceptive
Additional Keywords : Plant Extracts
[+]

Burdock extracts may be beneficial in the treatment of diabetes.Feb 28, 2017

Pubmed Data : Avicenna J Phytomed. 2017 Mar-Apr;7(2):169-179. PMID: 28348972
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hepatoprotective, Hypolipidemic
Additional Keywords : Plant Extracts
[+]

Burdock has protective effects against ethanol induced testicular injuries.Jul 12, 2018

Pubmed Data : Andrologia. 2018 Jul 13:e13086. Epub 2018 Jul 13. PMID: 30003584
Article Published Date : Jul 12, 2018
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Alcohol Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
[+]

Burdock root attenuates preneoplastic lesion development.Dec 04, 2019

Pubmed Data : Environ Toxicol. 2019 Dec 5. Epub 2019 Dec 5. PMID: 31804025
Article Published Date : Dec 04, 2019
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Liver Cancer, Nonalcoholic fatty liver disease (NAFLD), Preneoplastic Conditions
Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antioxidants, Chemoprotective Agents, Hepatoprotective
Additional Keywords : Risk Reduction
[+]

Burdock root extract is a promising agent in the prevention of atherosclerosis.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2016 ;16(1):6. Epub 2016 Jan 8. PMID: 26746431
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Atherosclerosis, High Fat Diet, Hyperlipidemia
Pharmacological Actions : Anticholesteremic Agents
[+]

Ethanolic extract of root from Arctium lappa L ameliorates obesity and hepatic steatosis.Sep 30, 2022

Pubmed Data : J Food Biochem. 2022 Oct 1:e14455. Epub 2022 Oct 1. PMID: 36183168
Article Published Date : Sep 30, 2022
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Liver Steatosis, Obesity
Pharmacological Actions : Hepatoprotective
Additional Keywords : Anti-Obesity Agents
[+]

Habitual consumption of A. lappa root in the evening may aid the maintenance of healthy intestinal microbiota.Feb 05, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Microorganisms. 2020 Feb 6 ;8(2). Epub 2020 Feb 6. PMID: 32041173
Article Published Date : Feb 05, 2020
Study Type : Animal Study
Additional Links
Substances : Burdock
Pharmacological Actions : Gastrointestinal Agents
[+]

In vivo and in vitro anti-inflammatory effects of water-soluble polysaccharide from Arctium lappa.Aug 14, 2019

Pubmed Data : Int J Biol Macromol. 2019 Aug 15 ;135:717-724. Epub 2019 May 23. PMID: 31129217
Article Published Date : Aug 14, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Burdock
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Natural lignans from Arctium lappa as antiaging agents in Caenorhabditis elegans.Aug 31, 2015

Pubmed Data : Phytochemistry. 2015 Sep ;117:340-350. Epub 2015 Jul 1. PMID: 26141518
Article Published Date : Aug 31, 2015
Study Type : Animal Study
Additional Links
Substances : Burdock, Lignans
Diseases : Aging, Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Structural characterization of water-soluble polysaccharide from Arctium lappa and its effects on colitis mice.May 31, 2019

Pubmed Data : Carbohydr Polym. 2019 Jun 1 ;213:89-99. Epub 2019 Feb 27. PMID: 30879693
Article Published Date : May 31, 2019
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Supplementation with burdock has a wide spectrum of bioactive effects, including health promotion, performance improvement, and fatigue reduction.Oct 06, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Vet Med Sci. 2017 Oct 7 ;79(10):1698-1706. Epub 2017 Sep 11. PMID: 28890521
Article Published Date : Oct 06, 2017
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Fatigue
Additional Keywords : Plant Extracts
[+]

The current study indicated that arctigenin exerted anti-ulcer activity.Oct 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Rep. 2016 Nov ;5(5):589-594. Epub 2016 Oct 4. PMID: 27882222
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective, Interleukin-10 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

The effects of hypoglycemia and weight loss of total lignans from Fructus Arctii in KKAy mice and its mechanisms of the activity.Mar 31, 2018

Pubmed Data : Phytother Res. 2018 Apr ;32(4):631-642. Epub 2017 Dec 13. PMID: 29235180
Article Published Date : Mar 31, 2018
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Hypoglycemia
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
[+]

The extract of Arctium lappa fruit improves cancer-induced cachexia.Oct 18, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Oct 19 ;12(10). Epub 2020 Oct 19. PMID: 33086629
Article Published Date : Oct 18, 2020
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Cachexia: Cancer
Pharmacological Actions : Anti-Cachexic Agents
[+]

The lipid-lowering effects of fenugreek gum, hawthorn pectin, and burdock inulin.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2023 ;10:1149094. Epub 2023 Mar 23. PMID: 37032784
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Burdock, Fenugreek, Hawthorn
Diseases : Hyperlipidemia
Pharmacological Actions : Gastrointestinal Agents, Hypolipidemic
[+]

The results showed that the A. lappa L. polysaccharides regulated lipid metabolism through the PKC/NF-κB pathway in diabetic rats.Aug 31, 2019

Pubmed Data : Int J Biol Macromol. 2019 Sep 1 ;136:115-122. Epub 2019 Jun 10. PMID: 31195041
Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Diabetic Complications, Hyperlipidemia
Pharmacological Actions : Anticholesteremic Agents, Hypolipidemic, NF-kappaB Inhibitor
Additional Keywords : Polysaccharides
[+]

Total lignans from Fructus arctii has a preventive and therapeutic effect on diabetic retinopathy.Jun 11, 2020

Pubmed Data : J Ethnopharmacol. 2020 Jun 12 ;255:112773. Epub 2020 Mar 18. PMID: 32199990
Article Published Date : Jun 11, 2020
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Diabetic Retinopathy
Pharmacological Actions : Anti-Apoptotic, Vascular Endothelial Growth Factor Inhibitors
[+]

Treatment with A. lappa resulted in body weight decrease and blood glucose suppression.Aug 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lab Anim Res. 2017 Sep ;33(3):251-255. Epub 2017 Sep 27. PMID: 29046701
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Obesity
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Anti-Obesity Agents
[+]

A dried burdock root extract demonstrated anti-hyperglycemic properties.Aug 05, 2014

Pubmed Data : J Agric Food Chem. 2014 Aug 6 ;62(31):7738-45. Epub 2014 Jul 23. PMID: 24933284
Article Published Date : Aug 05, 2014
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Plant Extracts
[+]

A. lappa extracts are potential candidates for the treatment of inflammatory disorders that are complement-related.Oct 24, 2019

Pubmed Data : Chem Biodivers. 2019 Oct 25. Epub 2019 Oct 25. PMID: 31654480
Article Published Date : Oct 24, 2019
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

A. lappa may represent an interesting asset for researching and developing new therapies for inflammatory afflictions.Oct 04, 2022

Pubmed Data : Chem Biodivers. 2022 Oct 5. Epub 2022 Oct 5. PMID: 36198078
Article Published Date : Oct 04, 2022
Study Type : Review
Additional Links
Substances : Burdock
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

An ethyl acetate extract of burdock may be a promising neuroprotective agent for the prevention and treatment of neurodegenerative diseases.Jun 30, 2014

Pubmed Data : Environ Toxicol Pharmacol. 2014 Jul ;38(1):189-98. Epub 2014 Jun 7. PMID: 24956398
Article Published Date : Jun 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Oxidative Stress
Pharmacological Actions : Bax/Bcl2 ratio: Increase, Neuroprotective Agents, Superoxide Dismutase Up-regulation
Additional Keywords : Dose Response, Plant Extracts
[+]

Arctigenin significantly inhibited the migration and invasion of MDA-MB-231 cells.Dec 31, 2016

Pubmed Data : Oncol Rep. 2017 Jan ;37(1):179-184. Epub 2016 Nov 23. PMID: 27878294
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Arctiin attenuates high glucose-induced human retinal capillary endothelial cell proliferation.Apr 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2020 May ;24(10):5695-5706. Epub 2020 Apr 16. PMID: 32297701
Article Published Date : Apr 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Diabetic Retinopathy
Pharmacological Actions : Antiproliferative , Cell cycle arrest
[+]

Arctiin has great value in treating various tumors sheltering constitutively activated STAT3.Feb 28, 2019

Pubmed Data : Phytomedicine. 2019 Mar 1 ;55:282-292. Epub 2018 Aug 11. PMID: 30668440
Article Published Date : Feb 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Multiple Myeloma
Pharmacological Actions : Anti-Angiogenic, Antiproliferative , Apoptotic, STAT3 Inhibitor
Additional Keywords : Natural Substance/Drug Synergy, Plant Extracts
[+]

Arctiin inhibits cervical cancer cell migration and invasion.Feb 04, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2022 Feb 5 ;14(2). Epub 2022 Feb 5. PMID: 35214097
Article Published Date : Feb 04, 2022
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Cervical Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative
[+]

Arctiin may serve as a novel therapeutic agent for the treatment of osteoporosis.Dec 31, 2019

Pubmed Data : Pharmacol Res. 2020 09 ;159:104944. Epub 2020 May 23. PMID: 32454224
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Arctiin protected the UVB radiation‑mediated decrease in COL1A1 mRNA expression.Nov 30, 2017

Pubmed Data : Mol Med Rep. 2017 Dec ;16(6):9120-9124. Epub 2017 Oct 2. PMID: 28990056
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Ultraviolet Radiation Induced Damage
Pharmacological Actions : Photoprotective
[+]

Arctiin suppresses H9N2 avian influenza virus-mediated inflammation via activation of Nrf2/HO-1 signaling.Nov 25, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2021 Nov 26 ;21(1):289. Epub 2021 Nov 26. PMID: 34836523
Article Published Date : Nov 25, 2021
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Arctium lappa L. root extract induces cell death via mitochondrial-mediated caspase-dependent apoptosis in Jurkat human leukemic T cells.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Feb ;110:918-929. Epub 2018 Dec 17. PMID: 30572196
Article Published Date : Jan 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Acute T cell Leukemias
Pharmacological Actions : Apoptotic
Additional Keywords : Plant Extracts
[+]

Burdock and coltsfoot were shown to have anti-tubercular activity.Aug 07, 2014

Pubmed Data : J Ethnopharmacol. 2014 Aug 8 ;155(1):796-800. Epub 2014 Jun 20. PMID: 24955560
Article Published Date : Aug 07, 2014
Study Type : In Vitro Study
Additional Links
Substances : Burdock, Daisy
Diseases : Mycobacterium Tuberculosis
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
[+]

Burdock and oleamide attenuated allergic reactions in vitro.May 10, 2016

Pubmed Data : J Agric Food Chem. 2016 May 11 ;64(18):3564-73. Epub 2016 Apr 26. PMID: 27087645
Article Published Date : May 10, 2016
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Allergies
Pharmacological Actions : Anti-Allergic Agents, Histamine down-regulation, Interleukin-4 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Burdock contains anti-leukemic activity.Feb 01, 2006

Pubmed Data : Planta Med. 2006 Feb;72(3):276-8. PMID: 16534737
Article Published Date : Feb 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Leukemia
[+]

Burdock extracts may be regarded as potential antioxidant agents and possess potent neuroprotective activity against H2O2-induced injury.Mar 31, 2015

Pubmed Data : Cell Mol Neurobiol. 2015 Apr ;35(3):335-44. Epub 2014 Oct 29. PMID: 25352420
Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Bax/Bcl2 ratio: Increase, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Burdock extracts might be useful as a therapeutic agent for treating various forms of allergic inflammation.Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Mol Allergy. 2011 ;9(1):4. Epub 2011 Feb 8. PMID: 21303540
Article Published Date : Dec 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Allergies, Dermatitis: Contact, Inflammation
Pharmacological Actions : Anti-Allergic Agents, Anti-Inflammatory Agents, Interleukin-4 downregulation, Interleukin-5 downregulation, NF-kappaB Inhibitor
[+]

Burdock leaf extract significantly inhibited the formation of P. aeruginosa biofilm, as well as significantly decreasing virulence factors.Feb 28, 2017

Pubmed Data : J Appl Microbiol. 2017 Mar ;122(3):615-624. Epub 2017 Jan 18. PMID: 27860087
Article Published Date : Feb 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Pseudomonas aeruginosa
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Biofilm, Plant Extracts
[+]

Burdock leaf flavonoids could be used as a new type of functional factor for the development of antioxidant and anti-inflammatory foods.Jul 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2022 Aug ;10(8):2718-2726. Epub 2022 May 12. PMID: 35959264
Article Published Date : Jul 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Burdock, Flavonoids
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Burdock leaf is safe and affordable option for the preservation of meats.Jul 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Food Prot. 2016 Aug ;79(8):1404-9. PMID: 27497128
Article Published Date : Jul 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Foodborne Pathogens: Prevention/Food Preservation
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
[+]

Burdock root extract and its component chlorogenic acid have potential use in antibiofilm strategies against persistent K. pneumoniae infections.Mar 27, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Microbiol Biotechnol. 2017 Mar 28 ;27(3):542-551. PMID: 27974734
Article Published Date : Mar 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Burdock, Chlorogenic Acid
Diseases : Candida Albicans, Escherichia coli Infections, Klebsiella Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Biofilm, Plant Extracts
[+]

Changes in chemical components and antitumor activity during the heating process of Fructus Arctii.Nov 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2019 Dec ;57(1):363-368. PMID: 31295042
Article Published Date : Nov 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Promyelocytic leukemia
Pharmacological Actions : Antiproliferative
[+]

Enhancement of the apoptotic effects of Arctii fructus extracts on cancer cells by the enzymatic bioconversion of lignans.Apr 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2020 May ;8(5):2205-2213. Epub 2020 Apr 8. PMID: 32405377
Article Published Date : Apr 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Cancers: Drug Resistant, Colon Cancer, Lung Cancer
Pharmacological Actions : Apoptotic, Chemopreventive
[+]

Evaluation of antimicrobial and cytotoxic effects of Echinacea and Arctium extracts and Zataria essential oil.Jun 14, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : AMB Express. 2022 Jun 15 ;12(1):75. Epub 2022 Jun 15. PMID: 35705727
Article Published Date : Jun 14, 2022
Study Type : In Vitro Study
Additional Links
Substances : Burdock, Echinacea, Zataria multiflora
Diseases : Escherichia coli Infections, Staphylococcus aureus infection, Steptococcus Mutans Infections, Streptococcus Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation
[+]

Extraction and antioxidant activities of polysaccharides from roots of Arctium lappa L.Nov 12, 2018

Pubmed Data : Int J Biol Macromol. 2018 Nov 13 ;123:531-538. Epub 2018 Nov 13. PMID: 30439439
Article Published Date : Nov 12, 2018
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin, Burdock
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Polysaccharides
[+]

Fermented Arctium lappa fruit extract had an inhibitory effect on the IgE-mediated allergic response in RBL‑2H3 cells.Dec 27, 2015

Pubmed Data : Int J Mol Med. 2015 Dec 28. Epub 2015 Dec 28. PMID: 26707911
Article Published Date : Dec 27, 2015
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Allergies
Pharmacological Actions : Anti-Allergic Agents, Anti-Inflammatory Agents, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Dose Response
[+]

Induction of apoptosis, autophagy and ferroptosis by Thymus vulgaris and Arctium lappa extract.Oct 28, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Oct 29 ;25(21). Epub 2020 Oct 29. PMID: 33138135
Article Published Date : Oct 28, 2020
Study Type : In Vitro Study
Additional Links
Substances : Burdock, Thyme
Diseases : Leukemia, Multiple Myeloma
Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation
[+]

Intake of arctigenin could be an effective supplement for breast cancer patients.Dec 28, 2016

Pubmed Data : Int J Oncol. 2016 Dec 29. Epub 2016 Dec 29. PMID: 28035371
Article Published Date : Dec 28, 2016
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin, Burdock
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor
[+]

Lappaol F regulates the cell cycle by activating CDKN1C/p57 in human colorectal cancer cells.Nov 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2023 Dec ;61(1):337-344. PMID: 36708218
Article Published Date : Nov 30, 2023
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest
[+]

Mechanistic insights on burdock ( Arctium lappa L.) extract effects on diabetes mellitus.Jun 30, 2022

Pubmed Data : Food Sci Biotechnol. 2022 Jul ;31(8):999-1008. Epub 2022 Apr 25. PMID: 35873376
Article Published Date : Jun 30, 2022
Study Type : Review
Additional Links
Substances : Burdock
Diseases : Diabetes: Oxidative Stress, Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants
[+]

Medicinal herbs used in traditional management of breast cancer.Aug 13, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicines (Basel). 2020 Aug 14 ;7(8). Epub 2020 Aug 14. PMID: 32823812
Article Published Date : Aug 13, 2020
Study Type : Review
Additional Links
Substances : Black Cohosh, Burdock, Echinacea, Flaxseed, Garlic, Ginseng, Green Tea, Nigella sativa (aka Black Seed), Turmeric
Diseases : Breast Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Apoptotic
[+]

Natural lignans from Arctium lappa modulate P-glycoprotein efflux function in multidrug resistant cancer cells.Feb 14, 2015

Pubmed Data : Phytomedicine. 2015 Feb 15 ;22(2):301-7. Epub 2015 Jan 2. PMID: 25765837
Article Published Date : Feb 14, 2015
Study Type : In Vitro Study
Additional Links
Substances : Burdock, Lignans
Diseases : Cancers: Drug Resistant, Cancers: Multi-Drug Resistant, Colon Cancer
Pharmacological Actions : Chemosensitizer, Multidrug Resistance Gene Modulators
Additional Keywords : Chemotherapeutic Synergy: Doxorubicin
[+]

Neuroprotective effects of caffeoylquinic acid derivatives from the roots of Arctium lappa.Aug 31, 2020

Pubmed Data : Phytochemistry. 2020 Sep ;177:112432. Epub 2020 Jun 17. PMID: 32562918
Article Published Date : Aug 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Hydrogen Peroxide Induced Toxicity
Pharmacological Actions : Neuroprotective Agents
[+]

Onopordopicrin may be a potential therapeutic molecule to fight against oxidative stress in pathological specific muscle disorders.Mar 01, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Mar 2 ;26(5). Epub 2021 Mar 2. PMID: 33801315
Article Published Date : Mar 01, 2021
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Cachexia, Muscular Dystrophies, Oxidative Stress, Sarcopenia
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
[+]

Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa.Apr 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Pharmacol Sin. 2018 May ;39(5):787-801. Epub 2018 Apr 26. PMID: 29698388
Article Published Date : Apr 30, 2018
Study Type : Review
Additional Links
Substances : Arctigenin, Burdock
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Inflammatory Agents, Renoprotective
[+]

Proapoptotic and antiangiogenic activities of Arctium lappa on breast cancer cell lines.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Scientifica (Cairo). 2020 ;2020:7286053. Epub 2020 May 17. PMID: 32509375
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Breast Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Apoptotic
[+]

The anti-proliferative and apoptotic effect of Arctium lappa root extract was similar to doxorubicin.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2017 03 1 ;18(3):795-802. Epub 2017 Mar 1. PMID: 28441789
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs
[+]

The burdock phytochemical inulin has prebiotic properties that could promote health.Feb 01, 2008

Pubmed Data : Anaerobe. 2008 Feb;14(1):29-34. Epub 2007 Nov 26. PMID: 18042411
Article Published Date : Feb 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Burdock, Inulin
Diseases : Dysbiosis
[+]

The combination of curcumin, EGCG and arctigenin synergistically enhanced the anti-proliferative effects in both prostate and breast cancer cells.Aug 04, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : RSC Adv. 2014 Aug 5 ;4(66):35242-35250. PMID: 25243063
Article Published Date : Aug 04, 2014
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin, Burdock, Curcumin, EGCG (Epigallocatechin gallate), Green Tea
Diseases : Breast Cancer, Prostate Cancer
Pharmacological Actions : Antiproliferative , Chemopreventive
Additional Keywords : Natural Substance Synergy
[+]

The experimental mix extract of Arctium lappa root powder and Aloe vera gel is able to inhibit very resistant microorganisms.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clujul Med. 2017 ;90(3):344-347. Epub 2017 Jul 15. PMID: 28781531
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Aloe Vera, Burdock
Diseases : Candida Albicans, Enterococcus Infections
Pharmacological Actions : Anti-Bacterial Agents, Antifungal Agents
[+]

The immunomodulatory potential of selected bioactive plant-based compounds in breast cancer.Dec 31, 2016

Pubmed Data : Anticancer Agents Med Chem. 2017 ;17(6):770-783. PMID: 27539316
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Apricot, Arctigenin, beta-Carotene, Burdock, Curcumin, EGCG (Epigallocatechin gallate), Garlic, Ginseng, Licorice, Quinic acid, Turmeric
Diseases : Breast Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Chemotherapeutic, Immunomodulatory
Additional Keywords : Plant Extracts
[+]

These results provide evidence of novel anti-inflammatory mechanisms of A. lappaDec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:6346734. Epub 2018 Jan 18. PMID: 29576797
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Inflammation, Peritonitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

This report provides the first evidence for the in vitro schistosomicidal and antiherpes activities of Arctium lappa.Sep 30, 2017

Pubmed Data : Biomed Pharmacother. 2017 Oct ;94:489-498. Epub 2017 Aug 3. PMID: 28780467
Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Herpes Simplex Virus Type 1, Parasitic Diseases
Pharmacological Actions : Antiparasitic Agents, Antiviral Agents
Additional Keywords : Plant Extracts
[+]

This reviews natural plants as breast cancer preventatives or use in treatments. Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi Pharm J. 2016 May ;24(3):233-40. Epub 2016 May 5. PMID: 27275107
Article Published Date : Apr 30, 2016
Study Type : Review
Additional Links
Substances : Ashwagandha, Black Cohosh, Burdock, Echinacea, Flavonoids, Flaxseed, Garlic, Ginseng, Polyphenols, Turmeric
Diseases : Breast Cancer
Pharmacological Actions : Antioxidants, Antiproliferative , Chemopreventive
[+]

This study demonstrates that Arctii Fructus inhibits the proliferation and metastatic properties of colorectal cancer cellsDec 31, 2016

Pubmed Data : Am J Chin Med. 2017 ;45(6):1309-1325. Epub 2017 Aug 22. PMID: 28830210
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Cancer Metastasis, Colorectal Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords : Plant Extracts
[+]

This study has identified a new mechanism of action of arctigenin against liver cancer growth.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:268. Epub 2018 Mar 27. PMID: 29636686
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin, Burdock
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Chemopreventive
[+]

This study intends to provide reference for clinical use of traditional Chinese medicine to resist new coronavirus.Feb 29, 2020

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2020 Mar ;45(6):1225-1231. PMID: 32281329
Article Published Date : Feb 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Burdock, Ginger, Ginseng, Honeysuckle, Magnolia, Salvia miltiorrhiza
Diseases : Coronavirus Infection
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Cytokine Modulation, Cytokine Storm
[+]

Various herbs may have a therapeutic role in preventing and treating kidney and bladder stone formation. Jan 01, 1994

Pubmed Data : Int Urol Nephrol. 1994;26(5):507-11. PMID: 7860196
Article Published Date : Jan 01, 1994
Study Type : Review
Additional Links
Substances : Burdock, Dandelion , Horsetail, Lithospermum officinale, Silene saxifraga, Uva Ursi (aka Bearberry), Verbena officinalis
Diseases : Bladder Stones, Kidney Stones, Urolithiasis
[+]

Burdock has anti-allergic effects.Aug 14, 2008

Pubmed Data : Exp Biol Med (Maywood). 2008 Aug 14. PMID: 18703753
Article Published Date : Aug 14, 2008
Additional Links
Substances : Burdock
[+]

Topical application of Burdock (Arctium lappa) fruit extract improves the clinical signs of aging. Dec 01, 2008

Pubmed Data : J Cosmet Dermatol. 2008 Dec;7(4):281-9. PMID: 19146605
Article Published Date : Dec 01, 2008
Additional Links
Substances : Burdock
Diseases : Aging Skin

Copyright: volff / 123RF Stock Photo

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Though they have been used for centuries as medicine, medical science is finally beginning to look at the evidence proving that food and herbs are the most effective, powerful healers

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