Butterbur

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20 Diseases Researched for Butterbur

Name	AC	CK
Migraine Disorders	4	22
Asthma	3	21
Allergic Rhinitis	2	20
Asthma: Bronchial	2	20
Oxidative Stress	2	4
Brain Inflammation	2	3
Lipopolysaccharide-Induced Toxicity	2	3
Alzheimer's Disease	1	2
Chemically-Induced Liver Damage	1	2
Duodenal Ulcer	1	2
Gastric Ulcer	1	2
Allergies	1	1
Brain: Microglial Activation	1	1
Breast Cancer	1	1
Breast Cancer: Triple Negative	1	1
Chronic Obstructive Pulmonary Disease	1	1
Headaches	1	1
Inflammation	1	1
Obesity	1	1
Stroke: Ischemic	1	1

18 Pharmacological Actions Researched for Butterbur

Name	AC	CK
Leukotriene Antagonists	2	12
Antioxidants	4	7
Anti-Inflammatory Agents	4	5
Anti-Apoptotic	2	3
Heme oxygenase-1 up-regulation	2	3
Neuroprotective Agents	2	3
Nrf2 activation	2	3
Anti-Ulcer Agents	1	2
Anticholesteremic Agents	1	2
Cyclooxygenase 2 Inhibitors	2	2
Hepatoprotective	1	2
Anti-Allergic Agents	1	1
Cyclooxygenase 1 Inhibitor	1	1
Cyclooxygenase Inhibitors	1	1
Cytotoxic	1	1
Postaglandin PGE2 downregulation	1	1
Prophylactic Agents	1	1
Tumor Necrosis Factor (TNF) Alpha Inhibitor	1	1

Research Articles 24
Cumulative Knowledge Score 38
Overall Research Rating GOOD

View the Evidence:
24 Abstracts with Butterbur Research

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View the Evidence: 24 Abstracts with Butterbur Research

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Butterbur confers complementary anti-inflammatory activity in atopic asthmatic patients maintained on corticosteriods. Jan 01, 2004

Butterbur exhibits protection against chemically-induced nasal responsiveness in seasonal allergic rhinitis. Jul 01, 2003

Butterbur has significant therapeutic value for the prevention of migraine in children and adolescents.Mar 01, 2005

Butterbur is a safe and effective therapy for the treatment of asthma. Mar 01, 2004

Butterbur is an effective preventive treatment for migraine.Feb 01, 2009

Butterbur is as effective as fexofenadine in attenuating nasal symptoms in patients with perennial allergic rhinitis. Apr 01, 2004

Butterbur extract improves lipid profiles and antioxidant activities in monosodium L-glutamate-challenged mice.Sep 30, 2010

Butterbur leaves attenuate memory impairment and neuronal cell damage in amyloid beta-induced Alzheimer’s disease models.May 31, 2018

Butterbur's anti-leukotriene activity may be responsible for its beneficial effect on gastrointestinal ulcersDec 01, 1993

Evaluation of antioxidant activity of Petasites japonicus flower buds extracts. Feb 29, 2020

These findings provide the possible mechanism of the anti-neuroinflammatory properties of Petatewalide B.May 31, 2018

Acupuncture and supplementation with various nutrients and herbs may have therapeutic value in preventing migraines.Jun 01, 2010

Butterbur (P. hybridus) exhibits ant-inflammatory activity in rat microglial (brain) cells. Jan 01, 2005

Chemical constituents of the leaves of butterbur and their anti-inflammatory effects.Jan 28, 2019

Cytotoxic activities of sesquiterpenoids from the aerial parts of Petasites japonicus against cancer stem cells. Jun 12, 2020

Elimination of 'dietary triggers' and the inclusion of a number of natural substances may prevent migraines. Jun 01, 2008

Herbal treatments for migraine: a systematic review of randomised-controlled studies.Apr 19, 2020

Petatewalide B alleviates oxygen glucose deprivation/reoxygenation induced neuronal injury.Jun 30, 2020

Petatewalide B, a novel compound from Petasites japonicus with anti-allergic activity.Feb 02, 2016

S-isopetasin, a compound found in Butterbur, may be beneficial as a bronchodilator in the treatment of chronic obstructive pulmonary disease and asthma.Jan 01, 2006

These results suggest that butterbur is valuable in improving obesity-related inflammatory responses.Apr 28, 2020

A compound found within Butterbur has significant anti-angiogenic activity.Feb 01, 2004

Butterbur contains compunds that inhibit peptido-leukotrienes, contributing to the plant's vasorelaxant, gastroprotective and spasmolytic activities.Aug 01, 1994

Butterbur is effective for the treatment for intermittent allergic rhinitis symptoms and is well tolerated.Feb 01, 2001

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Butterbur

View the Evidence:
24 Abstracts with Butterbur Research