Cafestol

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17 Diseases Researched for Cafestol

Name	AC	CK
Diabetes Mellitus: Type 2	1	10
Obesity	1	10
Colon Cancer	1	3
Diabetes Mellitus: Type 2: Prevention	2	3
Kidney Cancer	3	3
Chemotherapy-Induced Toxicity: Doxorubicin	1	2
Diabetes Mellitus: Type 1	1	2
Liver Injury: Ischemia/reperfusion	1	2
Myocardial Fibrosis	1	2
Bone Diseases	1	1
Cardiomegaly	1	1
Coronavirus Infection	1	1
Head and Neck Cancer	1	1
Leukemia	1	1
Mesothelioma	1	1
Osteoarthritis	1	1
Pain	1	1

24 Pharmacological Actions Researched for Cafestol

Name	AC	CK
Antiproliferative	4	6
Apoptotic	6	6
Cardioprotective	3	5
Insulin-releasing	2	3
Anti-Apoptotic	1	2
Anti-Fibrotic	1	2
Anti-Inflammatory Agents	1	2
Anti-metastatic	2	2
Chemoprotective Agents	1	2
Hypoglycemic Agents	1	2
Nrf2 activation	2	2
Antinoceceptive	1	1
Antioxidants	1	1
Antiviral Agents	1	1
Bcl-2 protein down-regulation	1	1
Caspase-3 Activation	1	1
Cell cycle arrest	1	1
Chemosensitizer	1	1
Chemotherapeutic	1	1
Heme oxygenase-1 up-regulation	1	1
MicroRNA modulator	1	1
NF-kappaB Inhibitor	1	1
Osteogenic	1	1
Osteoprotective	1	1

Research Articles 17
Cumulative Knowledge Score 27
Overall Research Rating GOOD

View the Evidence:
17 Abstracts with Cafestol Research

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Focus Your Research

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View the Evidence: 17 Abstracts with Cafestol Research

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Cafestol may hold promise for weight and visceral fat reduction.Sep 23, 2024

Cafestol inhibits colon cancer cell proliferation and tumor growth.Jun 30, 2024

Cafestol inhibits high-glucose-induced cardiac fibrosis in cardiac fibroblasts and type 1-like diabetic rats.Dec 31, 2019

Cafestol may contribute to the reduced risk of developing type-2 diabetes in coffee consumers.Jul 31, 2017

Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury.Jun 30, 2020

Protective effect of cafestol against doxorubicin-induced cardiotoxicity in rats by activating the Nrf2 pathway.Dec 31, 2022

"The coffee specific diterpene cafestol induces peripheral pain-killing properties mediated by endogenous opioid peptides."Feb 14, 2012

Anti-proliferative and anti-migratory properties of coffee diterpenes kahweol acetate and cafestol in human renal cancer cells.Jan 11, 2021

Cafestol and kahweol are potential cancer treatments, or adjuvants as chemotherapeutic agents for malignant pleural mesothelioma.Jun 25, 2012

Cafestol could be applied in pharmacological therapy for cardiac diseases.Dec 31, 2018

Cafestol could have potential as a therapeutic agent for preventing cancers such as renal carcinoma.Apr 24, 2011

Cafestol may be a novel agent for bone diseases.Jun 30, 2015

cafestol may be effectively used to enhance ABT-737 sensitivity in cancer therapy via downregulation of Mcl-1 expression and upregulation of Bim expression. Dec 31, 2013

Cafestol may contribute to the preventive effects on T2D in coffee drinkers and be of therapeutic interest.Oct 22, 2015

Cafestol, a diterpene molecule found in coffee, induces leukemia cell death.Jul 31, 2017

Secondary metabolites from spice and herbs as potential multitarget inhibitors of SARS-CoV-2 proteins.Oct 26, 2020

Treatment of HNSCC cells with cafestol leads to a dose-dependent reduction of cell viability and to induction of apoptosis.May 31, 2015

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View the Evidence:
17 Abstracts with Cafestol Research