Caffeic acid phenethyl ester

Name	AC	CK
Oxidative Stress	12	23
Inflammation	8	18
Spinal Cord Injuries	4	16
Breast Cancer	11	15
Pesticide Toxicity	5	10
Prostate Cancer	6	10
Testicular Injury: Chemical/Metal Induced	5	10
Cancers: All	6	8
Ischemia	4	8
Chemically-Induced Liver Damage	4	7
Chemotherapy-Induced Toxicity: Cisplatin	5	7
Chemotherapy-Induced Toxicity: Doxorubicin	4	7
Parkinson's Disease	5	7
Breast Cancer: Triple Negative	5	6
Periodontal Diseases	2	6
Cadmium Poisoning	3	5
Lipopolysaccharide-Induced Toxicity	1	5
Nicotine/Tobacco Toxicity	1	5
Ovarian Cancer	4	5
Periodontitis	3	5
Wound Healing	3	5
Alzheimer's Disease	3	4
Chemotherapy-Induced Toxicity	2	4
Diabetic Complications	2	4
Kidney Damage: Chemically-Induced	2	4
Obesity	2	4
Ulcerative Colitis	2	4
Bladder Cancer	2	3
Brain Injury: Traumatic	2	3
Cancer Metastasis	2	3
Candida Albicans	3	3
Colitis	2	3
Glioma	2	3
Oral Cancer	2	3
Asthma	1	2
Bone Diseases	1	2
Bone Fractures	1	2
Brain Edema	1	2
Brain Inflammation	1	2
Candidiasis	1	2
Cardiac Hypertrophy	1	2
Cardiotoxicity: Chemotherapy-Induced	1	2
Cataract: Radiation-Induced	1	2
Chemobrain	1	2
Chemotherapy-Induced Toxicity: Gentamicin	1	2
Chemotherapy-Induced Toxicity: Paclitaxel	1	2
Chemotherapy-Induced Toxicity: Peripheral Neuropathy	1	2
Cognitive Decline/Dysfunction	1	2
Coronavirus Infection	2	2
Diabetes: Cardiovascular Illness	1	2
Diabetes: Memory Problems	1	2
Diabetes: Oxidative Stress	1	2
Diabetic Nephropathy	1	2
Diabetic Retinopathy	1	2
Electromagnetic Radiation Mitigation	1	2
Endometriosis	1	2
Endothelial Damage	1	2
Endotoxemia	1	2
Exercise-Induced Tissue Damage	1	2
Familial Adenomatous Polyposis	1	2
Fibrosis	1	2
Gastric Ulcer	1	2
Gastrointestinal Inflammation	1	2
Hypertension	1	2
Hypertension: Pulmonary	1	2
Hyperuricemia	1	2
Infertility: Male	1	2
Insulin Resistance	1	2
Intestinal Polyps	1	2
Kidney Damage	1	2
Kidney Failure	1	2
Lipid Peroxidation	1	2
Liver Damage	1	2
Liver Fibrosis	1	2
Lung Damage	1	2
Lung Inflammation	1	2
Melanoma	2	2
Methanol Toxicity	1	2
Mitochondrial Diseases	1	2
Mucositis	1	2
Myocardial Ischemia	1	2
Neurodegenerative Diseases	2	2
Neuropathic Pain	1	2
Nonalcoholic fatty liver disease (NAFLD)	1	2
Osteoarthritis	2	2
Otitis media	1	2
Pesticide-Induced Toxicity: Organophosphates	1	2
Polycystic Ovary Syndrome	1	2
Prostatic Hyperplasia: Benign	1	2
Radiation	1	2
Radiation Induced Illness	1	2
Squamous cell carcinoma	2	2
Steptococcus Mutans Infections	2	2
Subarachnoid hemorrhage	1	2
Testicular Injury: Cadmium-Induced	1	2
Traumatic Brain Injury	1	2
Ulcers	1	2
Acute Myeloid Leukemia	1	1
Allergies	1	1
Amphetamine Addiction/Withdrawal	1	1
Amyotrophic Lateral Sclerosis	1	1
Anxiety	1	1
Aortic Calcification	1	1
Cancers: Drug Resistant	1	1
Candida Glabrata	1	1
Candida Infection	1	1
Carcinoma: Non-Small-Cell Lung	1	1
Cervical Cancer	1	1
Colon Cancer	1	1
Colorectal Cancer	1	1
Coronavirus Disease (Covid-19)	1	1
Cystic Fibrosis	1	1
DNA damage	1	1
Depression	1	1
Diabetes Mellitus: Type 2	1	1
Diabetes: Cognitive Dysfunction	1	1
Ear Diseases	1	1
Epilepsy	1	1
Gastric Cancer	1	1
Glaucoma	1	1
Gout	1	1
Head and Neck Cancer	1	1
Huntington Disease	1	1
Infection: Antibiotic Resistant	1	1
Inflammatory Bowel Diseases	1	1
Laryngeal Cancer	1	1
Liver Cancer	1	1
Lung Cancer	1	1
Multiple Myeloma	1	1
Multiple Sclerosis	1	1
Nasopharyngeal Cancer	1	1
Non-Small-Cell Lung Carcinoma	1	1
Osteosarcoma	1	1
Pancreatic Cancer	1	1
Prion Diseases	1	1
Radiotherapy	1	1
Skin Diseases: Photo-Aging	1	1
Stroke	1	1

Name	AC	CK
Anti-Inflammatory Agents	45	87
Antioxidants	42	77
Neuroprotective Agents	27	45
Antiproliferative	28	36
NF-kappaB Inhibitor	15	28
Apoptotic	21	24
Tumor Necrosis Factor (TNF) Alpha Inhibitor	9	23
Anti-Apoptotic	12	21
Interleukin-6 Downregulation	6	18
Hepatoprotective	9	17
Chemoprotective Agents	10	16
Renoprotective	7	14
Nrf2 activation	5	11
Radioprotective	6	10
Anti-metastatic	7	9
Chemosensitizer	7	7
Chemotherapeutic	5	7
Cell cycle arrest	5	6
Interleukin-1 beta downregulation	4	6
Malondialdehyde Down-regulation	3	6
Cardioprotective	3	5
Cyclooxygenase 2 Inhibitors	3	5
Heme oxygenase-1 up-regulation	3	5
Radiosensitizer	5	5
Anti-Fibrotic	2	4
Antifungal Agents	3	4
Antineoplastic Agents	3	4
Immunomodulatory	3	4
Anti-Bacterial Agents	2	3
Anticarcinogenic Agents	2	3
Antimicrobial	3	3
Chemopreventive	3	3
Cytotoxic	3	3
Hypolipidemic	2	3
Matrix metalloproteinase-3 (MMP-3) inhibitor	2	3
Pancreato Protective Agents	2	3
Vascular Endothelial Growth Factor Inhibitors	2	3
Angiogenesis Inhibitors	2	2
Anti-Angiogenic	1	2
Anti-Ulcer Agents	1	2
Antihypertensive Agents	1	2
Antiviral Agents	2	2
Cytoprotective	1	2
Enzyme Inhibitors	1	2
Gastrointestinal Agents	1	2
Interleukin-10 upregulation	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	2
Matrix metalloproteinase-9 (MMP-9) inhibitor	1	2
MicroRNA modulator	1	2
Osteoprotective	1	2
Superoxide Dismutase Up-regulation	1	2
Tumor Necrosis Factor (TNF) Alpha Enhancer	1	2
Uricosuric Agents	1	2
Wnt/β-catenin signaling pathway modulation	1	2
Anti-Allergic Agents	1	1
Autophagy Inhibitors	1	1
Autophagy Up-regulation	1	1
Bcl-2 protein down-regulation	1	1
Epidermal growth factor receptor (EGFR) inhibitor	1	1
Genoprotective	1	1
Heme oxygenase-1 inducer	1	1
Interleukin-8 downregulation	1	1
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	1	1
Matrix metalloproteinase-1 (MMP-1) inhibitor	1	1
Osteogenic	1	1
Photoprotective	1	1
Proteasome Inhibitors	1	1
STAT3 Inhibitor	1	1
Survivin Down-Regulation	1	1
Tumor Suppressor Protein p53 Upregulation	1	1

[+]

Caffeic acid phenethyl ester inhibits cell proliferation and up-regulates the antioxidant levels in HSC-T6 cells.Feb 20, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : World J Gastroenterol. 2017 Feb 21 ;23(7):1203-1214. PMID: 28275300

Article Published Date : Feb 20, 2017

Study Type : Human In Vitro

Additional Links

Substances : Caffeic acid phenethyl ester

Pharmacological Actions : Antioxidants, Nrf2 activation

[+]

Caffeic acid phenethyl ester reduces the adverse effects of nicotine on the endometrium.Aug 31, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Med Sci. 2023 Sep ;48(5):493-500. PMID: 37786469

Article Published Date : Aug 31, 2023

Study Type : Human In Vitro

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Nicotine/Tobacco Toxicity

[+]

Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT.Mar 12, 2024

Click here to read the entire abstract

Pubmed Data : Cancer Gene Ther. 2024 Mar 13. Epub 2024 Mar 13. PMID: 38480977

Article Published Date : Mar 12, 2024

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Cancers: All, Prostate Cancer

Pharmacological Actions : Antiproliferative

[+]

Evaluation of efficacy of curcumin and caffeic acid phenethyl ester in breast cancer by preclinical studies.Mar 20, 2024

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Pubmed Data : Curr Med Chem. 2024 Mar 21. Epub 2024 Mar 21. PMID: 38523543

Article Published Date : Mar 20, 2024

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester, Curcumin

Diseases : Breast Cancer

Pharmacological Actions : Apoptotic

Additional Keywords : Natural Substance Synergy

[+]

Role of CAPE in reducing oxidative stress in animal models with traumatic brain injury Aug 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ann Med Surg (Lond). 2020 Sep ;57:118-122. Epub 2020 Jul 22. PMID: 32760580

Article Published Date : Aug 31, 2020

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Brain Injury: Traumatic

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

Aggressive mammary cancers lacking lymphocytic infiltration arise in irradiated mice and can be prevented by dietary intervention.Dec 11, 2019

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Pubmed Data : Cancer Immunol Res. 2019 Dec 12. Epub 2019 Dec 12. PMID: 31831632

Article Published Date : Dec 11, 2019

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Breast Cancer

Pharmacological Actions : Anticarcinogenic Agents, Immunomodulatory, Radioprotective

Anti Therapeutic Actions : Radation Exposure: Low-Dose

[+]

Analysis of potential protective effects of caffeic acid phenethyl ester against gentamicin ototoxicity.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Basic Med Sci. 2022 Jan ;25(1):121-125. PMID: 35656452

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Chemotherapy-Induced Toxicity: Gentamicin

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Chemoprotective Agents

[+]

Anti-glioma effects of Caffeic acid phenethyl ester and Dasatinib combination therapy in an in vivo glioma model.May 14, 2018

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Pubmed Data : Anticancer Agents Med Chem. 2018 May 15. Epub 2018 May 15. PMID: 29766825

Article Published Date : May 14, 2018

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Glioma

Pharmacological Actions : Antiproliferative , Chemotherapeutic

[+]

Attenuating effects of caffeic acid phenethyl ester and betaine on abamectin-induced hepatotoxicity and nephrotoxicity.Mar 26, 2018

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Pubmed Data : Environ Sci Pollut Res Int. 2018 Mar 27. Epub 2018 Mar 27. PMID: 29589235

Article Published Date : Mar 26, 2018

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Pesticide Toxicity

Pharmacological Actions : Antioxidants, Hepatoprotective, Renoprotective

Problem Substances : Pesticides

[+]

Better neuroprotective profile of caffeic acid phenyl ester over resveratrol in non-traumatic ischemia-reperfusion injury of the spinal cord.Dec 08, 2021

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Pubmed Data : Br J Neurosurg. 2021 Dec 9:1-7. Epub 2021 Dec 9. PMID: 34879774

Article Published Date : Dec 08, 2021

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Ischemia, Spinal Cord Injuries

Pharmacological Actions : Neuroprotective Agents

[+]

Caffeic acid phenethyl ester (CAPE) has a protective effect on oxidative stress in rat liver exposed to the 900 MHz electromagnetic field.Jun 30, 2009

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Pubmed Data : Toxicol Ind Health. 2009 Jul ;25(6):429-34. PMID: 19671636

Article Published Date : Jun 30, 2009

Study Type : Animal Study

Additional Links

Substances : Bee Propolis, Caffeic acid phenethyl ester

Diseases : Electromagnetic Radiation Mitigation, Lipid Peroxidation, Oxidative Stress

Pharmacological Actions : Antioxidants, Radioprotective

Anti Therapeutic Actions : Electromagnetic Radiation

[+]

Caffeic acid phenethyl ester alleviated hypouricemia in hyperuricemic mice through inhibiting XOD and up-regulating OAT3.Jul 31, 2022

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Pubmed Data : Phytomedicine. 2022 Aug ;103:154256. Epub 2022 Jun 8. PMID: 35714456

Article Published Date : Jul 31, 2022

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Hyperuricemia

Pharmacological Actions : Uricosuric Agents

[+]

Caffeic acid phenethyl ester alleviates airway inflammation and remodelling in chronic asthma by balancing the airway microenvironment.Oct 12, 2016

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Pubmed Data : Free Radic Biol Med. 2016 Oct 13 ;101:163-175. Epub 2016 Aug 13. PMID: 27746262

Article Published Date : Oct 12, 2016

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Asthma

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

Caffeic acid phenethyl ester ameliorates imidacloprid-induced acute toxicity in the rat cerebral cortex.Sep 29, 2022

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Pubmed Data : Environ Toxicol Pharmacol. 2022 Sep 30:103980. Epub 2022 Sep 30. PMID: 36191819

Article Published Date : Sep 29, 2022

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Pesticide Toxicity

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Enhancer

Problem Substances : Pesticides

[+]

Caffeic acid phenethyl ester ameliorates metabolic disease by inducing PPARγ activity and adipose tissue remodelling.Mar 04, 2018

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Pubmed Data : Mol Nutr Food Res. 2018 Mar 5. Epub 2018 Mar 5. PMID: 29508519

Article Published Date : Mar 04, 2018

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Obesity

Pharmacological Actions : Anti-Inflammatory Agents, Hypolipidemic

Additional Keywords : Anti-Inflammatory Agents, Caffeic acid phenethyl ester, Hypolipidemic, obesity

[+]

Caffeic acid phenethyl ester ameliorates pulmonary inflammation and apoptosis reducing Nf-κβ activation in blunt pulmonary contusion model.Jul 31, 2019

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Pubmed Data : Ulus Travma Acil Cerrahi Derg. 2019 Aug ;25(5):433-439. PMID: 31475327

Article Published Date : Jul 31, 2019

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Lung Damage, Lung Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

[+]

Caffeic acid phenethyl ester ameliorates titanium particle-induced bone loss and inflammatory reaction.Nov 11, 2023

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Pubmed Data : Biochem Biophys Res Commun. 2023 Nov 12 ;681:47-54. Epub 2023 Sep 20. PMID: 37751634

Article Published Date : Nov 11, 2023

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Bone Diseases, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Caffeic acid phenethyl ester attenuates dextran sulfate sodium-induced ulcerative colitis.Feb 28, 2022

Click here to read the entire abstract

Pubmed Data : Appl Biochem Biotechnol. 2022 Mar ;194(3):1091-1104. Epub 2022 Jan 18. PMID: 35040047

Article Published Date : Feb 28, 2022

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Ulcerative Colitis

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

[+]

Caffeic acid phenethyl ester attenuates indomethacin-induced gastric ulcer.Sep 22, 2023

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Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2023 Sep 23. Epub 2023 Sep 23. PMID: 37740773

Article Published Date : Sep 22, 2023

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Gastric Ulcer

Pharmacological Actions : Anti-Ulcer Agents

Problem Substances : Indomethacin

[+]

Caffeic acid phenethyl ester attenuates liver fibrosis.Feb 09, 2017

Click here to read the entire abstract

Pubmed Data : Biochem Biophys Res Commun. 2017 Feb 10. Epub 2017 Feb 10. PMID: 28193525

Article Published Date : Feb 09, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Liver Fibrosis

Pharmacological Actions : Hepatoprotective

[+]

Caffeic acid phenethyl ester attenuates neuropathic pain.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Pain Res. 2018 ;11:2709-2719. Epub 2018 Nov 1. PMID: 30464588

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Neuropathic Pain

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

[+]

Caffeic acid phenethyl ester attenuates paclitaxel-induced peripheral neuropathyAug 28, 2022

Click here to read the entire abstract

Pubmed Data : Curr Neurovasc Res. 2022 Aug 29. Epub 2022 Aug 29. PMID: 36043777

Article Published Date : Aug 28, 2022

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy

Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents

[+]

Caffeic acid phenethyl ester can ameliorate on insulin resistance through modulation of JNK and NF-κB signalling pathway in mice and HepG2 cells.Aug 10, 2017

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2017 Aug 11. Epub 2017 Aug 11. PMID: 28799756

Article Published Date : Aug 10, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Insulin Resistance

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

[+]

Caffeic acid phenethyl ester can demonstrate protective effects on endothelial damage, inflammation and oxidative stress axis.Jun 29, 2020

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Pubmed Data : Arch Ital Biol. 2020 Jun 30 ;158(2):37-44. PMID: 33462797

Article Published Date : Jun 29, 2020

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Endothelial Damage, Exercise-Induced Tissue Damage, Oxidative Stress

Therapeutic Actions : Exercise

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

Caffeic acid phenethyl ester could attenuate the effects of chronic renal failure.Dec 26, 2021

Click here to read the entire abstract

Pubmed Data : Drug Chem Toxicol. 2021 Dec 27:1-12. Epub 2021 Dec 27. PMID: 34957889

Article Published Date : Dec 26, 2021

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Kidney Failure

Pharmacological Actions : Antioxidants, Renoprotective

[+]

Caffeic acid phenethyl ester could be considered as a promising neuroprotective agent against progressive neurodegenerative diseases.Jul 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Aging Dis. 2018 Aug ;9(4):605-622. Epub 2018 Aug 1. PMID: 30090650

Article Published Date : Jul 31, 2018

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Alzheimer's Disease

Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation

[+]

Caffeic acid phenethyl ester could be used for supportive and protective therapy against pesticide intoxication.Jun 29, 2016

Click here to read the entire abstract

Pubmed Data : Biochem Genet. 2016 Jun 30. Epub 2016 Jun 30. PMID: 27365043

Article Published Date : Jun 29, 2016

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Pesticide Toxicity

Pharmacological Actions : Cytoprotective, Pancreato Protective Agents

Problem Substances : Dichlorvos

[+]

Caffeic acid phenethyl ester counteracts doxorubicin-induced chemobrain.Dec 14, 2020

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Pubmed Data : Neuropharmacology. 2020 Dec 15 ;181:108334. Epub 2020 Oct 1. PMID: 33011199

Article Published Date : Dec 14, 2020

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Chemobrain, Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, Neuroprotective Agents

[+]

Caffeic acid phenethyl ester guards against benign prostate hypertrophy.Mar 29, 2018

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Pubmed Data : IUBMB Life. 2018 Mar 30. Epub 2018 Mar 30. PMID: 29603556

Article Published Date : Mar 29, 2018

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Prostatic Hyperplasia: Benign

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Caffeic acid phenethyl ester has a preventive effect on early brain injury after subarachnoid hemorrhage.Mar 17, 2020

Click here to read the entire abstract

Pubmed Data : World Neurosurg. 2020 Mar 18. Epub 2020 Mar 18. PMID: 32200016

Article Published Date : Mar 17, 2020

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester, Propolis: Bee

Diseases : Subarachnoid hemorrhage

Pharmacological Actions : Neuroprotective Agents

[+]

Caffeic acid phenethyl ester has a protective effect against sevoflurane induced neurotoxicity in neonatal rats.Aug 03, 2016

Click here to read the entire abstract

Pubmed Data : Mol Med Rep. 2016 Aug 4. Epub 2016 Aug 4. PMID: 27498600

Article Published Date : Aug 03, 2016

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

Problem Substances : Anaesthetic Gases

[+]

Caffeic acid phenethyl ester increased NDRG1 expression through phosphorylation of ERK1/2 to repress oral squamous cell carcinoma cells growth.Feb 08, 2017

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2017 Feb 9. Epub 2017 Feb 9. PMID: 28181403

Article Published Date : Feb 08, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Oral Cancer

Pharmacological Actions : Antiproliferative

Additional Keywords : Gene Expression Regulation

[+]

Caffeic acid phenethyl ester inhibits neuro-inflammation and oxidative stress following spinal cord injury.Mar 24, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Transl Med. 2024 Mar 25 ;22(1):304. Epub 2024 Mar 25. PMID: 38528569

Article Published Date : Mar 24, 2024

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Inflammation, Mitochondrial Diseases, Oxidative Stress, Spinal Cord Injuries

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

[+]

Caffeic acid phenethyl ester inhibits the growth of bladder carcinoma cells by upregulating growth differentiation factor 15.Oct 14, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed J. 2021 Oct 15. Epub 2021 Oct 15. PMID: 34662721

Article Published Date : Oct 14, 2021

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Bladder Cancer

Pharmacological Actions : Antiproliferative

[+]

Caffeic acid phenethyl ester inhibits the progression of ovarian cancer.Feb 28, 2018

Click here to read the entire abstract

Pubmed Data : Biomed Pharmacother. 2018 Mar ;99:825-831. Epub 2018 Feb 20. PMID: 29710481

Article Published Date : Feb 28, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Ovarian Cancer

Pharmacological Actions : Antiproliferative , NF-kappaB Inhibitor

[+]

Caffeic acid phenethyl ester is an effective antitumor agent for human androgen-dependent and -independent prostate carcinoma cells.Jan 05, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancers (Basel). 2022 Jan 6 ;14(2). Epub 2022 Jan 6. PMID: 35053438

Article Published Date : Jan 05, 2022

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Prostate Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative

[+]

Caffeic acid phenethyl ester is effective in resolving colon fibrosis in chronic inflammation.Aug 23, 2018

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Pubmed Data : Pathol Res Pract. 2018 Aug 24. Epub 2018 Aug 24. PMID: 30170869

Article Published Date : Aug 23, 2018

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Colitis, Fibrosis, Gastrointestinal Inflammation

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents

[+]

Caffeic acid phenethyl ester is protective in experimental ulcerative colitisMay 19, 2017

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Pubmed Data : Inflammopharmacology. 2017 May 20. Epub 2017 May 20. PMID: 28528363

Article Published Date : May 19, 2017

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Ulcerative Colitis

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Caffeic acid phenethyl ester loaded PEG-PLGA nanoparticles enhance wound healing in diabetic rats.Dec 26, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxidants (Basel). 2022 Dec 27 ;12(1). Epub 2022 Dec 27. PMID: 36670922

Article Published Date : Dec 26, 2022

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Diabetic Complications, Wound Healing

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Caffeic acid phenethyl ester may be a potential therapeutic agent for patients with advanced PCa.May 14, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2016 May 15. Epub 2016 May 15. PMID: 27191743

Article Published Date : May 14, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Bee Propolis, Caffeic acid phenethyl ester

Diseases : Cancer Metastasis, Prostate Cancer

Pharmacological Actions : Anti-metastatic, Chemotherapeutic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Wnt/β-catenin signaling pathway modulation

[+]

Caffeic acid phenethyl ester may be protective against damage caused by cisplatin in the testicles.Jul 05, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Turk J Med Sci. 2020 Jul 6. Epub 2020 Jul 6. PMID: 32628437

Article Published Date : Jul 05, 2020

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Antioxidants, Chemoprotective Agents, Malondialdehyde Down-regulation

[+]

Caffeic acid phenethyl ester may play an important role in the regulation of cardiac hypertrophy induced by pressure overload.Apr 23, 2017

Click here to read the entire abstract

Pubmed Data : Life Sci. 2017 Apr 24. Epub 2017 Apr 24. PMID: 28449869

Article Published Date : Apr 23, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Cardiac Hypertrophy

Pharmacological Actions : Cardioprotective

[+]

Caffeic acid phenethyl ester mitigates cadmium-induced hepatotoxicity.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ecotoxicol Environ Saf. 2021 Jan 1 ;207:111578. Epub 2020 Nov 3. PMID: 33254423

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Chemically-Induced Liver Damage, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Hepatoprotective, MicroRNA modulator

Problem Substances : Cadmium

[+]

Caffeic acid phenethyl ester mitigates cognitive impairment in aged mice following anesthesia and surgery.Mar 12, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxidants (Basel). 2023 Mar 13 ;12(3). Epub 2023 Mar 13. PMID: 36978961

Article Published Date : Mar 12, 2023

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

Caffeic acid phenethyl ester mitigates infertility: A crucial role of metalloproteinase and angiogenic factor in cadmium-induced testicular damage.Nov 16, 2021

Click here to read the entire abstract

Pubmed Data : J Biochem Mol Toxicol. 2021 Nov 17:e22960. Epub 2021 Nov 17. PMID: 34791780

Article Published Date : Nov 16, 2021

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Infertility: Male, Testicular Injury: Cadmium-Induced, Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Anti-Apoptotic, Matrix metalloproteinase-3 (MMP-3) inhibitor, Vascular Endothelial Growth Factor Inhibitors

[+]

Caffeic Acid Phenethyl Ester prevented HFCS-induced cardiovascular abnormalities.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oxid Med Cell Longev. 2016 ;2016:3419479. Epub 2016 Mar 2. PMID: 27042260

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Pharmacological Actions : Cardioprotective, Enzyme Inhibitors, NF-kappaB Inhibitor

Problem Substances : High Fructose Corn Syrup

[+]

Caffeic acid phenethyl ester prevented the neurodegenerations in brain tissue in chlorpyrifos induced Parkinson's disease.Dec 31, 2017

Click here to read the entire abstract

Pubmed Data : Pestic Biochem Physiol. 2018 Jan ;144:36-41. Epub 2017 Nov 10. PMID: 29463406

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Parkinson's Disease, Pesticide Toxicity

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Chlorpyrifos

[+]

Caffeic acid phenethyl ester promotes wound healing of mice pressure ulcers.May 31, 2018

Click here to read the entire abstract

Pubmed Data : Life Sci. 2018 Jun 1. Epub 2018 Jun 1. PMID: 29864436

Article Published Date : May 31, 2018

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Ulcers, Wound Healing

[+]

Caffeic acid phenethyl ester protects against photothrombotic cortical ischemic injury in mice.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Korean J Physiol Pharmacol. 2018 Jan ;22(1):101-110. Epub 2017 Dec 22. PMID: 29302217

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Ischemia

Pharmacological Actions : Anti-Inflammatory Agents, Heme oxygenase-1 up-regulation, Interleukin-10 upregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Anti-Inflammatory Agents, Caffeic acid phenethyl ester, Heme oxygenase-1 up-regulation, Ischemia

[+]

Caffeic acid phenethyl ester protects kidney mitochondria against ischemia/reperfusion induced injury.May 07, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxidants (Basel). 2021 May 8 ;10(5). Epub 2021 May 8. PMID: 34066715

Article Published Date : May 07, 2021

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Ischemia, Kidney Damage

Pharmacological Actions : Antioxidants, Renoprotective

[+]

Caffeic acid phenethyl ester protects the brain against hexavalent chromium toxicity.Apr 28, 2017

Click here to read the entire abstract

Pubmed Data : Biomed Pharmacother. 2017 Apr 29 ;91:303-311. Epub 2017 Apr 29. PMID: 28463793

Article Published Date : Apr 28, 2017

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

Caffeic acid phenethyl ester reduces ischemia-induced kidney mitochondrial injury in rats.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oxid Med Cell Longev. 2017 ;2017:1697018. Epub 2017 Aug 13. PMID: 28883899

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Ischemia

Pharmacological Actions : Renoprotective

[+]

Caffeic acid phenethyl ester reduces pro inflammatory cytokines.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Inflamm Res. 2021 ;14:5653-5657. Epub 2021 Nov 1. PMID: 34754212

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Caffeic acid phenethyl ester rescued streptozotocin-induced memory loss.Feb 23, 2018

Click here to read the entire abstract

Pubmed Data : Biomed Pharmacother. 2018 Feb 24 ;101:162-173. Epub 2018 Feb 24. PMID: 29486334

Article Published Date : Feb 23, 2018

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Diabetes: Memory Problems

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

Additional Keywords : Anti-Inflammatory Agents, Antioxidants, Caffeic acid phenethyl ester, Diabetes: Memory Problems, Neuroprotective Agents

[+]

Caffeic acid phenethyl ester rescues pulmonary arterial hypertension.Mar 21, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2019 Mar 22 ;20(6). Epub 2019 Mar 22. PMID: 30909527

Article Published Date : Mar 21, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Hypertension: Pulmonary

Pharmacological Actions : Antihypertensive Agents

[+]

Caffeic acid phenethyl ester reversed cadmium-induced cell death in hippocampus and cortex and subsequent cognitive disorders.Sep 30, 2020

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2020 Oct ;144:111636. Epub 2020 Jul 30. PMID: 32739455

Article Published Date : Sep 30, 2020

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Brain Inflammation , Cadmium Poisoning

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Neuroprotective Agents

Problem Substances : Cadmium

[+]

Caffeic acid phenethyl ester should be considered in the prevention of oxidative stress in diabetic liver.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Bratisl Lek Listy. 2016 ;117(5):276-82. PMID: 27215964

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Diabetic Complications, Liver Damage, Oxidative Stress

Pharmacological Actions : Antioxidants

[+]

Caffeic acid phenethyl ester treatment ameliorates oxidative stress in the serum and liver in a rat model of acute methanol intoxication.Apr 29, 2016

Click here to read the entire abstract

Pubmed Data : Ir J Med Sci. 2016 Apr 30. Epub 2016 Apr 30. PMID: 27139198

Article Published Date : Apr 29, 2016

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Methanol Toxicity, Oxidative Stress

Pharmacological Actions : Antioxidants, Hepatoprotective

Problem Substances : Methanol

[+]

Caffeic acid phenethyl ester treatment provided protection against fluoxetine toxicity.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2016 ;2016:1247191. Epub 2016 Apr 10. PMID: 27144157

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Pharmacological Actions : Hepatoprotective

Problem Substances : Fluoxetine (trade name Prozac)

[+]

Caffeic acid phenethyl ester, a coffee polyphenol, inhibits DNA methylation in vitro and in vivo.Nov 14, 2020

Click here to read the entire abstract

Pubmed Data : Eur J Pharmacol. 2020 Nov 15 ;887:173464. Epub 2020 Aug 8. PMID: 32781171

Article Published Date : Nov 14, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Additional Keywords : DNA Methylation, Epigenetic Modification

[+]

Caffeic acid phenethyl ester, a compound found within propolis causes regression of experimental endometriosis.Apr 01, 2007

Click here to read the entire abstract

Pubmed Data : Reprod Sci. 2007 Apr;14(3):270-9. PMID: 17636241

Article Published Date : Apr 01, 2007

Study Type : Animal Study

Additional Links

Substances : Bee Propolis, Caffeic acid phenethyl ester

Diseases : Endometriosis

Pharmacological Actions : Antioxidants, Cyclooxygenase 2 Inhibitors

[+]

Caffeic acid phenetyl ester, a compound found within bee propolis, protects against doxorubucin-induced cardiotoxicity in rats. Sep 30, 2010

Click here to read the entire abstract

Pubmed Data : Am J Ind Med. 2010 Sep 30. Epub 2010 Sep 30. PMID: 14745846

Article Published Date : Sep 30, 2010

Study Type : Animal Study

Additional Links

Substances : Bee Propolis, Caffeic acid phenethyl ester

Diseases : Cardiotoxicity: Chemotherapy-Induced, Chemotherapy-Induced Toxicity, Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Antioxidants

Additional Keywords : Drug: Doxorubicin

[+]

Caffeic acid phenetyl ester, a compound found within bee propolis, protects the diabetic heart against oxidative stress. Feb 01, 2005

Click here to read the entire abstract

Pubmed Data : Clin Biochem. 2005 Feb;38(2):191-6. PMID: 15642285

Article Published Date : Feb 01, 2005

Study Type : Animal Study

Additional Links

Substances : Bee Propolis, Caffeic acid phenethyl ester

Diseases : Diabetes: Cardiovascular Illness, Oxidative Stress

Pharmacological Actions : Antioxidants

[+]

Caffeic acid phenyl ester could have an important role in otitis media treatment.Apr 30, 2017

Click here to read the entire abstract

Pubmed Data : Int J Pediatr Otorhinolaryngol. 2017 May ;96:94-99. Epub 2017 Mar 7. PMID: 28390622

Article Published Date : Apr 30, 2017

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Otitis media

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Caffeic acid's role in mitigating polycystic ovary syndrome.Sep 30, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Pharmacother. 2023 Oct ;166:115327. Epub 2023 Aug 22. PMID: 37619480

Article Published Date : Sep 30, 2023

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Oxidative Stress, Polycystic Ovary Syndrome

Pharmacological Actions : Anti-Apoptotic, Antioxidants

[+]

CAPE seems to be effective agent and may be related to its potent antioxidant, anti-inflammatory properties and action as an Nrf2 activator.Aug 31, 2017

Click here to read the entire abstract

Pubmed Data : Environ Toxicol Pharmacol. 2017 Sep ;54:80-92. Epub 2017 Jun 28. PMID: 28704754

Article Published Date : Aug 31, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Cadmium Poisoning , Diabetic Nephropathy, Kidney Damage: Chemically-Induced

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Nrf2 activation, Renoprotective

Problem Substances : Cadmium

[+]

Comparison of the protective effects of curcumin and caffeic acid phenethyl ester against doxorubicin-induced testicular toxicity.Nov 30, 2020

Click here to read the entire abstract

Pubmed Data : Andrologia. 2020 Dec 1:e13919. Epub 2020 Dec 1. PMID: 33289171

Article Published Date : Nov 30, 2020

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester, Curcumin

Diseases : Chemotherapy-Induced Toxicity: Doxorubicin, Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents

[+]

Curcumin and caffeic acid phenethyl ester decrease intestinal tumors in an animal model of familial adenomatous polyposis.May 01, 2000

Click here to read the entire abstract

Pubmed Data : Carcinogenesis. 2000 May;21(5):921-7. PMID: 10783313

Article Published Date : May 01, 2000

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester, Curcumin

Diseases : Familial Adenomatous Polyposis, Intestinal Polyps

Pharmacological Actions : Antiproliferative

[+]

Curcumin and CAPE may reduce chemotherapy-induced mucosal barrier injury. Feb 01, 2004

Click here to read the entire abstract

Pubmed Data : Leukemia. 2004 Feb;18(2):276-84. PMID: 14671640

Article Published Date : Feb 01, 2004

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester, Curcumin

Diseases : Chemotherapy-Induced Toxicity, Mucositis

Pharmacological Actions : Antineoplastic Agents, NF-kappaB Inhibitor

[+]

Effects of caffeic acid phenethyl ester in reducing cerebral edema.Aug 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ann Med Surg (Lond). 2020 Sep ;57:328-333. Epub 2020 Aug 15. PMID: 32874565

Article Published Date : Aug 31, 2020

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Brain Edema, Traumatic Brain Injury

Pharmacological Actions : Neuroprotective Agents

[+]

Intralipid and caffeic acid phenethyl ester reverse the neurotoxic effects of organophosphate poisoning in rats.May 31, 2023

Click here to read the entire abstract

Pubmed Data : Niger J Clin Pract. 2023 Jun ;26(6):686-693. PMID: 37470640

Article Published Date : May 31, 2023

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Oxidative Stress, Pesticide-Induced Toxicity: Organophosphates

Pharmacological Actions : Antioxidants, Neuroprotective Agents

Problem Substances : Organophosphate Pesticides

[+]

Intrathecal CAPE administration following SCI decreases tissue and serum IL-6 levels as well as decreases spinal cord edema and microhemorrage.Apr 26, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Turk Neurosurg. 2017 Apr 27. Epub 2017 Apr 27. PMID: 28585671

Article Published Date : Apr 26, 2017

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Spinal Cord Injuries

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation

[+]

Investigation of the anti-inflammatory effects of caffeic acid phenethyl ester.Nov 30, 2021

Click here to read the entire abstract

Pubmed Data : Hum Exp Toxicol. 2021 Dec ;40(12_suppl):S721-S738. Epub 2021 Nov 18. PMID: 34789018

Article Published Date : Nov 30, 2021

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors

[+]

Melatonin and caffeic acid phenethyl ester prevent renal tubular injury by reducing oxidative stress and protect the kidney from oxidative damage induced by 900 MHz mobile phone.Aug 01, 2005

Click here to read the entire abstract

Pubmed Data : Mol Cell Biochem. 2005 Aug ;276(1-2):31-7. PMID: 16132682

Article Published Date : Aug 01, 2005

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester, Melatonin

Diseases : Radiation Induced Illness

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation

Adverse Pharmacological Actions : Nephrotoxic

[+]

Neuroprotective effect of intrastriatal caffeic acid phenethyl ester treatment in 6-OH dopamine model of Parkinson's disease.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Parkinsons Dis. 2021 ;2021:5553480. Epub 2021 Aug 30. PMID: 34512945

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Propolis contains a compound which inhibits triple negative breast cancer in the animal model. Sep 01, 2011

Click here to read the entire abstract

Pubmed Data : Cancer Lett. 2011 Sep 1;308(1):43-53. Epub 2011 May 13. PMID: 21570765

Article Published Date : Sep 01, 2011

Study Type : Animal Study

Additional Links

Substances : Bee Propolis, Caffeic acid phenethyl ester

Diseases : Breast Cancer, Breast Cancer: Triple Negative

Pharmacological Actions : Anti-Angiogenic, Apoptotic, Cell cycle arrest, NF-kappaB Inhibitor

[+]

Propolis enriched with CAPE might serve as a promising therapeutic agent for the treatment of NAFLD.Jun 01, 2022

Click here to read the entire abstract

Pubmed Data : Acta Pharmacol Sin. 2022 Jun 2. Epub 2022 Jun 2. PMID: 35655096

Article Published Date : Jun 01, 2022

Study Type : Animal Study

Additional Links

Substances : Bee Propolis, Caffeic acid phenethyl ester

Diseases : Nonalcoholic fatty liver disease (NAFLD), Obesity

Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective

[+]

Propolis, caffeic acid phenethyl ester, and pollen have beneficial effects on renal injury in hypertensive rats.Jul 31, 2017

Click here to read the entire abstract

Pubmed Data : Cell Biochem Funct. 2017 Aug ;35(6):304-314. Epub 2017 Aug 22. PMID: 28833317

Article Published Date : Jul 31, 2017

Study Type : Animal Study

Additional Links

Substances : Bee Pollen, Bee Propolis, Caffeic acid phenethyl ester

Diseases : Hypertension

Pharmacological Actions : Renoprotective

[+]

Propolis, caffeic acid phenethyl ester, nigella sativa oil and thymoquinone could prevent cataractogenesis in ionizing radiation-induced cataracts in the lenses of rats.Apr 09, 2015

Click here to read the entire abstract

Pubmed Data : Wien Klin Wochenschr. 2015 Apr 10. Epub 2015 Apr 10. PMID: 25860848

Article Published Date : Apr 09, 2015

Study Type : Animal Study

Additional Links

Substances : Bee Propolis, Caffeic acid phenethyl ester, Nigella sativa (aka Black Seed), Thymoquinone

Diseases : Cataract: Radiation-Induced

Pharmacological Actions : Radioprotective

Additional Keywords : Plant Extracts

Anti Therapeutic Actions : Low Dose Ionizing Radiation

[+]

Protection of CAPE-pNO 2 against chronic myocardial ischemia.Nov 23, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Inflammation. 2021 Nov 24. Epub 2021 Nov 24. PMID: 34817763

Article Published Date : Nov 23, 2021

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Myocardial Ischemia

Pharmacological Actions : Anti-Apoptotic, Anti-Fibrotic, Anti-Inflammatory Agents

[+]

Protective effect of caffeic acid phenethyl ester against imidacloprid-induced hepatotoxicity.Feb 29, 2020

Click here to read the entire abstract

Pubmed Data : Pestic Biochem Physiol. 2020 Mar ;164:122-129. Epub 2020 Jan 7. PMID: 32284117

Article Published Date : Feb 29, 2020

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Chemically-Induced Liver Damage, Inflammation, Oxidative Stress, Pesticide Toxicity

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Hepatoprotective

Problem Substances : Pesticides

[+]

Protective effects of caffeic acid phenethyl ester and thymoquinone against cigarette smoke.Aug 31, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Oral Biol Craniofac Res. 2022 Sep-Oct;12(5):610-616. Epub 2022 Aug 14. PMID: 35989976

Article Published Date : Aug 31, 2022

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Bone Fractures

Pharmacological Actions : Osteoprotective

[+]

Protective effects of caffeic acid phenethyl ester and thymoquinone on toluene induced liver toxicity.Feb 28, 2019

Click here to read the entire abstract

Pubmed Data : Biotech Histochem. 2019 Mar 1:1-6. Epub 2019 Mar 1. PMID: 30821514

Article Published Date : Feb 28, 2019

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Hepatoprotective

Problem Substances : Toluene

[+]

Protective effects of caffeic acid phenethyl ester on cadmium-induced testicular injury.Apr 30, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Heliyon. 2021 May ;7(5):e06965. Epub 2021 May 5. PMID: 34027170

Article Published Date : Apr 30, 2021

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Antioxidants

Problem Substances : Cadmium

[+]

Protective effects of caffeic acid phenethyl ester on the heart in experimental periodontitis against oxidative stress in rats.Jun 30, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Dent Med Probl. 2021 Jul-Sep;58(3):335-341. PMID: 34597478

Article Published Date : Jun 30, 2021

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Oxidative Stress, Periodontitis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Malondialdehyde Down-regulation

[+]

Protective effects of curcumin and caffeic acid phenethyl ester against cisplatin-induced testis tissue damageMar 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2018 Apr ;15(4):3404-3412. Epub 2018 Jan 31. PMID: 29545862

Article Published Date : Mar 31, 2018

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester, Curcumin

Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Chemoprotective Agents

[+]

Radioprotective role of natural polyphenols: from sources to mechanisms. Apr 17, 2021

Click here to read the entire abstract

Pubmed Data : Anticancer Agents Med Chem. 2021 Apr 18. Epub 2021 Apr 18. PMID: 33874875

Article Published Date : Apr 17, 2021

Study Type : Animal Study

Additional Links

Substances : Apigenin, Caffeic acid phenethyl ester, Curcumin, EGCG (Epigallocatechin gallate), Epicatechin, Gallic Acid, Polyphenols, Quercetin, Resveratrol, Rutin, Silibinin

Diseases : Radiation

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Radioprotective

[+]

The anti-biofilm efficacy of caffeic acid phenethyl ester.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Cell Infect Microbiol. 2021 ;11:700305. Epub 2021 Aug 2. PMID: 34408988

Article Published Date : Dec 31, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Candidiasis

Pharmacological Actions : Anti-Bacterial Agents, Antifungal Agents

Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation

[+]

The present study demonstrated that CAPE treatment may decrease the oxidative stress in the retina.Jun 23, 2021

Click here to read the entire abstract

Pubmed Data : Cutan Ocul Toxicol. 2021 Jun 24:1-6. Epub 2021 Jun 24. PMID: 34165369

Article Published Date : Jun 23, 2021

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Diabetes: Oxidative Stress, Diabetic Retinopathy

Pharmacological Actions : Antioxidants

[+]

The protective effect of caffeic acid phenethyl ester in the nephrotoxicity induced by α-cypermethrin.Dec 31, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Open Med (Wars). 2023 ;18(1):20230781. Epub 2023 Aug 11. PMID: 37588661

Article Published Date : Dec 31, 2022

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Renoprotective

Problem Substances : Cypermethrin

[+]

This experimental study revealed that CAPE administration significantly prevented alveolar bone loss and stimulated periodontal tissue healing.Nov 30, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Dent Sci. 2019 Dec ;14(4):339-345. Epub 2019 May 7. PMID: 31890119

Article Published Date : Nov 30, 2019

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Endotoxemia, Periodontitis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation

[+]

A comparison of the migration rate inhibition of breast cancer cells treated by caffeic acid and caffeic acid phenethyl ester.Oct 18, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2017 Oct 19 ;9(10). Epub 2017 Oct 19. PMID: 29048370

Article Published Date : Oct 18, 2017

Study Type : In Vitro Study

Additional Links

Substances : Caffeic Acid, Caffeic acid phenethyl ester

Pharmacological Actions : Anti-metastatic, Apoptotic, Cytotoxic

[+]

A low dose combination of withaferin A and caffeic acid phenethyl ester possesses anti-metastatic potential.Feb 02, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancers (Basel). 2022 Feb 3 ;14(3). Epub 2022 Feb 3. PMID: 35159054

Article Published Date : Feb 02, 2022

Study Type : In Vitro Study

Additional Links

Substances : Ashwagandha, Caffeic acid phenethyl ester

Diseases : Cancer Metastasis

Pharmacological Actions : Anti-metastatic

[+]

A number of plant polyphenols have chemosensitizing and radiosensitizing activity. Nov 01, 2005

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Pubmed Data : Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1630-47. PMID: 16356126

Article Published Date : Nov 01, 2005

Study Type : Review

Additional Links

Substances : Betulinic acid, Caffeic acid phenethyl ester, Curcumin, Emodin, Flavonoids, Genistein, Green Tea, Polyphenols, Resveratrol, Silymarin, Ursolic Acid

Diseases : Cancers: Drug Resistant

Pharmacological Actions : Chemosensitizer, Radiosensitizer

[+]

Anti-COVID-19 potential of withaferin-A and caffeic acid phenethyl ester.Jan 23, 2024

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Pubmed Data : Curr Top Med Chem. 2024 Jan 24. Epub 2024 Jan 24. PMID: 38279743

Article Published Date : Jan 23, 2024

Study Type : In Vitro Study

Additional Links

Substances : Ashwagandha, Caffeic acid phenethyl ester

Diseases : Coronavirus Disease (Covid-19)

Pharmacological Actions : Antiviral Agents

[+]

Anti-tumour potential and selectivity of caffeic acid phenethyl ester in osteosarcoma cells.Nov 26, 2021

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Pubmed Data : Tissue Cell. 2021 Nov 27 ;74:101705. Epub 2021 Nov 27. PMID: 34864499

Article Published Date : Nov 26, 2021

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Osteosarcoma

Pharmacological Actions : Antiproliferative

Additional Keywords : Selective Antiproliferation

[+]

Antifungal activity of the phenolic compounds ellagic acid and caffeic acid phenethyl ester against drug-resistant Candida auris.Sep 14, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Fungi (Basel). 2021 Sep 15 ;7(9). Epub 2021 Sep 15. PMID: 34575801

Article Published Date : Sep 14, 2021

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester, Ellagic Acid

Diseases : Candida Infection

Pharmacological Actions : Antifungal Agents

Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation

[+]

Antifungal and anti-biofilm effects of caffeic acid phenethyl ester on different candida species.Nov 06, 2021

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Pubmed Data : Antibiotics (Basel). 2021 Nov 7 ;10(11). Epub 2021 Nov 7. PMID: 34827297

Article Published Date : Nov 06, 2021

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Candida Albicans, Candida Glabrata

Pharmacological Actions : Antifungal Agents

Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation

[+]

Antioxidant activity of CAPE in vitro can protect human sperm deoxyribonucleic acid from oxidative damage.Jan 31, 2018

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Pubmed Data : Acta Histochem. 2018 Feb ;120(2):117-121. Epub 2018 Jan 8. PMID: 29325972

Article Published Date : Jan 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : DNA damage

Pharmacological Actions : Antioxidants, Genoprotective

Additional Keywords : Antioxidants, Caffeic acid phenethyl ester, DNA damage, Genoprotective

[+]

Antioxidant effect of caffeic acid phenethyl ester in experimentally induced periodontitis.Mar 25, 2021

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Pubmed Data : Clin Oral Investig. 2021 Mar 26. Epub 2021 Mar 26. PMID: 33770282

Article Published Date : Mar 25, 2021

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Periodontitis

Pharmacological Actions : Antioxidants

[+]

Caffeic acid and caffeic acid phenethyl ester induce apoptosis and cell cycle arrest of breast cancer cells MDA-MB-231.Sep 14, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2017 Sep 15 ;22(9). Epub 2017 Sep 15. PMID: 28926932

Article Published Date : Sep 14, 2017

Study Type : In Vitro Study

Additional Links

Substances : Caffeic Acid, Caffeic acid phenethyl ester

Diseases : Breast Cancer: Triple Negative

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Antiproliferative, Apoptotic, Breast Cancer: Triple Negative, Caffeic Acid, Caffeic acid phenethyl ester, Cell cycle arrest

[+]

Caffeic acid and caffeic acid phenethyl ester Induction of cell cycle arrest and apoptotic response of head and neck squamous carcinoma cells.Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2017 ;2017:6793456. Epub 2017 Jan 12. PMID: 28167973

Article Published Date : Dec 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Caffeic Acid, Caffeic acid phenethyl ester

Diseases : Head and Neck Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

[+]

Caffeic acid phenethyl ester (CAPE): Biosynthesis, derivatives and formulations with neuroprotective activities.Jul 26, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxidants (Basel). 2023 Jul 27 ;12(8). Epub 2023 Jul 27. PMID: 37627495

Article Published Date : Jul 26, 2023

Study Type : Review

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Neurodegenerative Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

[+]

Caffeic acid phenethyl ester against cadmium induced toxicity mediated by circRNA modulates autophagy in HepG2 cells.Jun 30, 2020

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Pubmed Data : Ecotoxicol Environ Saf. 2020 Jul 1 ;197:110610. Epub 2020 Apr 13. PMID: 32298858

Article Published Date : Jun 30, 2020

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Cadmium Poisoning , Chemically-Induced Liver Damage

Pharmacological Actions : Autophagy Inhibitors, Hepatoprotective

Problem Substances : Cadmium

[+]

Caffeic acid phenethyl ester ameliorates calcification.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2020 ;11:826. Epub 2020 Jul 7. PMID: 32733235

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Aortic Calcification

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

[+]

Caffeic acid phenethyl ester and caffeamide derivatives suppress oral squamous cell carcinoma cells.Jun 05, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2023 Jun 6 ;24(12). Epub 2023 Jun 6. PMID: 37372967

Article Published Date : Jun 05, 2023

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Oral Cancer, Squamous cell carcinoma

Pharmacological Actions : Apoptotic

[+]

Caffeic acid phenethyl ester as a DHODH inhibitor and its synergistic anticancer properties in combination with 5-fluorouracil.Dec 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Exp Pharmacol. 2022 ;14:243-253. Epub 2022 Jul 23. PMID: 35910085

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Breast Cancer

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil

[+]

Caffeic acid phenethyl ester assisted by reversible electroporation - in vitro study on human melanoma cells.May 23, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pharmaceutics. 2020 May 24 ;12(5). Epub 2020 May 24. PMID: 32456290

Article Published Date : May 23, 2020

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Melanoma

Pharmacological Actions : Cytotoxic

[+]

Caffeic acid phenethyl ester at low concentrations can positively module the osteogenesis in vitro. Aug 04, 2021

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Pubmed Data : Tissue Cell. 2021 Aug 5 ;73:101618. Epub 2021 Aug 5. PMID: 34391938

Article Published Date : Aug 04, 2021

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Osteoarthritis

Pharmacological Actions : Osteogenic

[+]

Caffeic acid phenethyl ester attenuates changes in pancreatic tissue damage biomarkers induced by cisplatin.Dec 10, 2019

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Pubmed Data : Can J Physiol Pharmacol. 2019 Dec 11. Epub 2019 Dec 11. PMID: 31825661

Article Published Date : Dec 10, 2019

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Chemotherapy-Induced Toxicity: Cisplatin

Pharmacological Actions : Chemoprotective Agents, Pancreato Protective Agents

[+]

Caffeic acid phenethyl ester attenuates nuclear factor κB mediated inflammatory responses in Müller cells and protects against retinal ganglion cell death.May 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Med Rep. 2019 Jun ;19(6):4863-4871. Epub 2019 Apr 11. PMID: 31059064

Article Published Date : May 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Glaucoma

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Caffeic acid phenethyl ester attenuates osteoarthritis progression.Oct 31, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Med. 2022 Nov ;50(5). Epub 2022 Sep 14. PMID: 36102306

Article Published Date : Oct 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Osteoarthritis

Pharmacological Actions : Anti-Inflammatory Agents, Heme oxygenase-1 up-regulation, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor, NF-kappaB Inhibitor, Nrf2 activation

[+]

Caffeic acid phenethyl ester augmented tamoxifen cytotoxicity via multiple mechanisms.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oxid Med Cell Longev. 2016 ;2016:3017108. Epub 2015 Nov 30. PMID: 26697130

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Breast Cancer

Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Synergy with Tamoxifen

[+]

Caffeic acid phenethyl ester could be a promising agent against nasopharyngeal carcinoma.May 07, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2018 May 8 ;19(5). Epub 2018 May 8. PMID: 29738439

Article Published Date : May 07, 2018

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Nasopharyngeal Cancer

Pharmacological Actions : Antiproliferative , STAT3 Inhibitor

[+]

Caffeic acid phenethyl ester exerts apoptotic and oxidative stress on human multiple myeloma cells.Nov 21, 2018

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Pubmed Data : Invest New Drugs. 2018 Nov 22. Epub 2018 Nov 22. PMID: 30465316

Article Published Date : Nov 21, 2018

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Multiple Myeloma

Pharmacological Actions : Apoptotic

[+]

Caffeic acid phenethyl ester has promising potential in chemoprevention of hepatocellular carcinomas.Jun 30, 2016

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Pubmed Data : Mol Cell Biochem. 2016 Jul ;418(1-2):13-20. Epub 2016 Jun 3. PMID: 27260301

Article Published Date : Jun 30, 2016

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Liver Cancer

Pharmacological Actions : Apoptotic, Chemopreventive

[+]

Caffeic acid phenethyl ester induced apoptosis in serous ovarian cancer OV7 cells.Jul 30, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2020 Jul 31 ;25(15). Epub 2020 Jul 31. PMID: 32752091

Article Published Date : Jul 30, 2020

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Ovarian Cancer

Pharmacological Actions : Apoptotic

[+]

Caffeic acid phenethyl ester induces apoptosis in colorectal cancer cells via inhibition of survivin.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Turk J Biol. 2020 ;44(5):264-274. Epub 2020 Oct 13. PMID: 33110364

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Colorectal Cancer

Pharmacological Actions : Apoptotic, Survivin Down-Regulation

[+]

Caffeic acid phenethyl ester induces radiosensitization via inhibition of DNA damage repair in androgen-independent prostate cancer cells.Jan 09, 2022

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Pubmed Data : Environ Toxicol. 2022 Jan 10. Epub 2022 Jan 10. PMID: 35006630

Article Published Date : Jan 09, 2022

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Prostate Cancer

Pharmacological Actions : Apoptotic, Radiosensitizer

[+]

Caffeic acid phenethyl ester inhibits cross-kingdom biofilm formation of Streptococcus mutans and Candida albicans.Aug 17, 2022

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Pubmed Data : Microbiol Spectr. 2022 Aug 18:e0157822. Epub 2022 Aug 18. PMID: 35980199

Article Published Date : Aug 17, 2022

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Candida Albicans, Steptococcus Mutans Infections

Pharmacological Actions : Antimicrobial

Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation

[+]

Caffeic acid phenethyl ester inhibits MDA-MB-231 cell proliferation in inflammatory microenvironment.Nov 30, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Pharmacother. 2023 Dec ;168:115766. Epub 2023 Oct 19. PMID: 37864895

Article Published Date : Nov 30, 2023

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Breast Cancer: Triple Negative

Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative , Hypolipidemic, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Caffeic acid phenethyl ester inhibits pseudo-allergic reactions.Aug 31, 2022

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Pubmed Data : Arch Pharm Res. 2022 Sep ;45(9):644-657. Epub 2022 Oct 2. PMID: 36183260

Article Published Date : Aug 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Allergies

Pharmacological Actions : Anti-Allergic Agents

[+]

Caffeic acid phenethyl ester inhibits the proliferation of HEp2 cells.Jul 29, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biol Pharm Bull. 2019 Jul 30. Epub 2019 Jul 30. PMID: 31366853

Article Published Date : Jul 29, 2019

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Laryngeal Cancer

Pharmacological Actions : Antiproliferative , Cell cycle arrest

[+]

Caffeic acid phenethyl ester inhibits ubiquitination and degradation of p53 and blocks cervical cancer cell growth.Aug 28, 2022

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Pubmed Data : Curr Mol Med. 2022 Aug 29. Epub 2022 Aug 29. PMID: 36043765

Article Published Date : Aug 28, 2022

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Cervical Cancer

Pharmacological Actions : Antiproliferative , Tumor Suppressor Protein p53 Upregulation

[+]

Caffeic acid phenethyl ester loaded electrospun nanofibers for wound dressing application.Sep 29, 2021

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Pubmed Data : J Pharm Sci. 2021 Sep 30. Epub 2021 Sep 30. PMID: 34600940

Article Published Date : Sep 29, 2021

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Wound Healing

Pharmacological Actions : Antimicrobial, Antioxidants

[+]

Caffeic acid phenethyl ester may be a useful adjunctive compound in the treatment of lung adenocarcinoma.Mar 01, 2018

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Pubmed Data : J Nutr Biochem. 2018 Mar 2 ;56:205-214. Epub 2018 Mar 2. PMID: 29597147

Article Published Date : Mar 01, 2018

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Non-Small-Cell Lung Carcinoma

Pharmacological Actions : Chemosensitizer, NF-kappaB Inhibitor

Additional Keywords : Chemotherapeutic Synergy: Doxorubicin

[+]

Caffeic acid phenethyl ester may hold promising prospects in treating inflammation-induced tumors.Sep 25, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Complement Altern Med. 2017 Sep 26 ;17(1):471. Epub 2017 Sep 26. PMID: 28950845

Article Published Date : Sep 25, 2017

Study Type : In Vitro Study

Additional Links

Substances : Bee Propolis, Caffeic acid phenethyl ester

Diseases : Breast Cancer, Breast Cancer: Triple Negative

Pharmacological Actions : Anti-Inflammatory Agents, Antineoplastic Agents, Antiproliferative , Apoptotic, Autophagy Up-regulation

[+]

Caffeic acid phenethyl ester maybe a promising agent for the prevention of skin photoaging via targeting histone acetyltransferase.Jun 21, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2019 Jun 22 ;20(12). Epub 2019 Jun 22. PMID: 31234539

Article Published Date : Jun 21, 2019

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Skin Diseases: Photo-Aging

Pharmacological Actions : Matrix metalloproteinase-1 (MMP-1) inhibitor, Photoprotective

[+]

Caffeic acid phenethyl ester mediates apoptosis in serum-starved HT29 colon cancer cells.Feb 29, 2024

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Pubmed Data : Cell Biochem Funct. 2024 Mar ;42(2):e3942. PMID: 38379263

Article Published Date : Feb 29, 2024

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Colon Cancer

Pharmacological Actions : Apoptotic

[+]

Caffeic acid phenethyl ester potentiates gastric cancer cell sensitivity to doxorubicin and cisplatin.Nov 25, 2018

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Pubmed Data : Anticancer Drugs. 2018 Nov 26. Epub 2018 Nov 26. PMID: 30489290

Article Published Date : Nov 25, 2018

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Gastric Cancer

Pharmacological Actions : Chemosensitizer, Chemotherapeutic, Proteasome Inhibitors

Additional Keywords : Chemotherapeutic Synergy: Cisplatin, Chemotherapeutic Synergy: Doxorubicin

[+]

Caffeic acid phenethyl ester prevents colitis-associated cancer by inhibiting NLRP3 inflammasome.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Oncol. 2020 ;10:721. Epub 2020 May 6. PMID: 32435622

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Colitis, Inflammatory Bowel Diseases

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Caffeic acid phenethyl ester protects against doxorubicin-induced cardiotoxicity and increases chemotherapeutic efficacy.Dec 31, 2021

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Pubmed Data : Food Chem Toxicol. 2022 Jan ;159:112770. Epub 2021 Dec 13. PMID: 34915066

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

Additional Links

Substances : Bee Propolis, Caffeic acid phenethyl ester

Diseases : Breast Cancer, Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Cardioprotective, Chemoprotective Agents, Chemosensitizer

[+]

Caffeic acid phenethyl ester protects against experimental autoimmune encephalomyelitis by regulating T cell activities.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:7274342. Epub 2020 Oct 9. PMID: 33133349

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Multiple Sclerosis

Pharmacological Actions : Immunomodulatory

[+]

Caffeic acid phenethyl ester protects against oxidative stress and dampens inflammation via heme oxygenase 1.Feb 19, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Oral Sci. 2019 Feb 20 ;11(1):6. Epub 2019 Feb 20. PMID: 30783082

Article Published Date : Feb 19, 2019

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Inflammation, Oxidative Stress, Periodontal Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 inducer, NF-kappaB Inhibitor

[+]

Caffeic acid phenethyl ester protects PC12 cells against cisplatin-induced neurotoxicity.Apr 22, 2019

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Pubmed Data : Neurotox Res. 2019 Apr 23. Epub 2019 Apr 23. PMID: 31016689

Article Published Date : Apr 22, 2019

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Chemotherapy-Induced Toxicity: Cisplatin

Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents

[+]

Caffeic acid phenethyl ester protects PC12 cells from cisplatin-induced neurotoxicity.Dec 18, 2017

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Pubmed Data : Neurotox Res. 2017 Dec 19. Epub 2017 Dec 19. PMID: 29260495

Article Published Date : Dec 18, 2017

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Chemotherapy-Induced Toxicity: Cisplatin

Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents

[+]

Caffeic acid phenethyl ester reverses doxorubicin resistance in breast cancer cells.May 31, 2023

Click here to read the entire abstract

Pubmed Data : Kaohsiung J Med Sci. 2023 Jun ;39(6):605-615. Epub 2023 Mar 24. PMID: 36960852

Article Published Date : May 31, 2023

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Breast Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Doxorubicin

[+]

Caffeic acid phenethyl ester suppresses androgen receptor signaling and stability via inhibition of phosphorylation on Ser81 and Ser213.Aug 19, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cell Commun Signal. 2019 Aug 20 ;17(1):100. Epub 2019 Aug 20. PMID: 31429764

Article Published Date : Aug 19, 2019

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Prostate Cancer

Pharmacological Actions : Chemotherapeutic

[+]

Caffeic acid phenethyl ester suppresses EGFR/FAK/Akt signaling, migration, and tumor growth of prostate cancer cells.Jul 24, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Phytomedicine. 2023 Jul 25 ;116:154860. Epub 2023 May 3. PMID: 37201366

Article Published Date : Jul 24, 2023

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Prostate Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Epidermal growth factor receptor (EGFR) inhibitor

[+]

Caffeic acid phenethyl ester suppresses metastasis of breast cancer cells.Dec 31, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2023 ;18(7):e0289031. Epub 2023 Jul 25. PMID: 37490511

Article Published Date : Dec 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Breast Cancer, Breast Cancer: Triple Negative

Pharmacological Actions : Anti-metastatic, Antiproliferative

[+]

Caffeic acid phenethyl ester suppresses NLRP3 inflammasome activation.Dec 08, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2016 Dec 9 ;6:38622. Epub 2016 Dec 9. PMID: 27934918

Article Published Date : Dec 08, 2016

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Gout

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation

[+]

Caffeic acid phenethyl ester surmounts acquired resistance of AZD9291 in non-small cell lung cancer cells.Aug 08, 2023

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Pubmed Data : Biofactors. 2023 Aug 9. Epub 2023 Aug 9. PMID: 37555475

Article Published Date : Aug 08, 2023

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Antiproliferative , Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Gefitinib

[+]

Caffeic acid phenethyl ester synergistically enhances paclitaxel activity in ovarian cancer cells.Jul 31, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2023 Aug 1 ;28(15). Epub 2023 Aug 1. PMID: 37570782

Article Published Date : Jul 31, 2023

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Ovarian Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic

Additional Keywords : Chemothapeutic Synergy: Paclitaxel

[+]

Caffeic acid phenethyl ester synergistically enhances the antifungal activity of fluconazole against resistant Candida albicans.Jan 31, 2018

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2018 Feb 1 ;40:55-58. Epub 2018 Jan 2. PMID: 29496175

Article Published Date : Jan 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Candida Albicans, Infection: Antibiotic Resistant

Pharmacological Actions : Anti-Bacterial Agents

Additional Keywords : Anti-Bacterial Agents, Caffeic acid phenethyl ester, Natural Substance/Drug Synergy

[+]

Caffeic acid phenethyl ester targets ubiquitin-specific protease 8 and synergizes with cisplatin in endometrioid ovarian carcinoma cells.Jan 04, 2022

Click here to read the entire abstract

Pubmed Data : Biochem Pharmacol. 2022 Jan 5 ;197:114900. Epub 2022 Jan 5. PMID: 34995485

Article Published Date : Jan 04, 2022

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Ovarian Cancer

Pharmacological Actions : Chemosensitizer

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Caffeic acid phenethyl ester was found to act both as radioprotector and radiosensitizer.Dec 31, 2017

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Pubmed Data : Anticancer Agents Med Chem. 2018 ;18(4):468-475. PMID: 29141565

Article Published Date : Dec 31, 2017

Study Type : Review

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Substances : Caffeic acid phenethyl ester

Diseases : Cancers: All

Pharmacological Actions : Radioprotective, Radiosensitizer

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Caffeic acid phenethyl ester: A review on its pharmacological importance, and its association with free radicals, COVID-19, and radiotherapy.Dec 22, 2022

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Pubmed Data : Phytother Res. 2022 Dec 23. Epub 2022 Dec 23. PMID: 36562210

Article Published Date : Dec 22, 2022

Study Type : Review

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Substances : Caffeic acid phenethyl ester

Diseases : Cancers: All, Coronavirus Infection, Radiotherapy

Pharmacological Actions : Antiproliferative , Radioprotective, Radiosensitizer

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Caffeic acid phenethyl ester: Unveiling its potential as a potent apoptosis inducer for combating hypopharyngeal squamous cell carcinoma.Jan 31, 2024

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncol Rep. 2024 Feb ;51(2). Epub 2023 Dec 15. PMID: 38099422

Article Published Date : Jan 31, 2024

Study Type : In Vitro Study

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Substances : Caffeic acid phenethyl ester

Diseases : Squamous cell carcinoma

Pharmacological Actions : Apoptotic

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Caffeic acid versus caffeic acid phenethyl ester in the treatment of breast cancer MCF-7 Cells: migration rate inhibition.Sep 23, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Integr Cancer Ther. 2018 Sep 24:1534735418801521. Epub 2018 Sep 24. PMID: 30246565

Article Published Date : Sep 23, 2018

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative , Cytotoxic

[+]

CAPE influences a number of biochemical pathways, as well as several targets involved in ear diseases, in particular, in ototoxicity.Aug 31, 2015

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Pubmed Data : Mol Med Rep. 2015 Sep ;12(3):3231-5. Epub 2015 May 14. PMID: 25975288

Article Published Date : Aug 31, 2015

Study Type : Review

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Ear Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

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CAPE is an effective inhibitor of neutrophil elastase via direct interaction whereby it inhibits the migration and growth of PANC-1 cells.Mar 20, 2017

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Pubmed Data : Oncol Rep. 2017 Mar 21. Epub 2017 Mar 21. PMID: 28339071

Article Published Date : Mar 20, 2017

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Pancreatic Cancer

Pharmacological Actions : Antiproliferative

[+]

CAPE-pNO 2 ameliorates diabetic brain injury through modulating Alzheimer's disease.Dec 14, 2021

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Pubmed Data : Life Sci. 2021 Dec 15 ;287:119929. Epub 2021 Oct 29. PMID: 34743947

Article Published Date : Dec 14, 2021

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Alzheimer's Disease, Diabetes: Cognitive Dysfunction

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Nrf2 activation

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Combination of caffeic acid phenethyl ester and crocin realign potential molecular markers in U87-MG glioma cells.Dec 31, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Curr Ther Res Clin Exp. 2023 ;98:100695. Epub 2023 Feb 14. PMID: 36936719

Article Published Date : Dec 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester, Crocin

Diseases : Glioma

Pharmacological Actions : Antiproliferative , Apoptotic

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Effects of caffeic acid phenethyl ester on angiogenesis, apoptosis and oxidatıve stress ın various cancer cell lines.Apr 16, 2019

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Pubmed Data : Biotech Histochem. 2019 Apr 17:1-7. Epub 2019 Apr 17. PMID: 30991851

Article Published Date : Apr 16, 2019

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Cancers: All

Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Apoptotic

Additional Keywords : Selective Cytotoxicity

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Evaluation of the neuroprotective potential of caffeic acid phenethyl ester in a cellular model of Parkinson's disease.Sep 14, 2020

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Pubmed Data : Eur J Pharmacol. 2020 Sep 15 ;883:173342. Epub 2020 Jul 4. PMID: 32634439

Article Published Date : Sep 14, 2020

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Parkinson's Disease

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

[+]

In the present paper the therapeutic potential of CAPE in diabetes is extensively reviewed.Nov 17, 2016

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Pubmed Data : Curr Med Chem. 2016 Nov 18. Epub 2016 Aug 18. PMID: 27855625

Article Published Date : Nov 17, 2016

Study Type : Review

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Immunomodulatory

[+]

Interaction of olive oil-based propolis and caffeic acid phenethyl ester with methylprednisolone used in the treatment of human acute myeloid leukemia.Apr 19, 2024

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Pubmed Data : Mol Biol Rep. 2024 Apr 20 ;51(1):559. Epub 2024 Apr 20. PMID: 38643306

Article Published Date : Apr 19, 2024

Study Type : In Vitro Study

Additional Links

Substances : Bee Propolis, Caffeic acid phenethyl ester, Olive

Diseases : Acute Myeloid Leukemia

Pharmacological Actions : Antiproliferative , Apoptotic

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Investigation of the inhibitory potential of caffeic acid phenethyl ester on prion replication, amplification, and fibril formation.Jul 05, 2024

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Pubmed Data : Zhonghua Yu Fang Yi Xue Za Zhi. 2024 Jul 6 ;58(7):1011-1019. PMID: 39034785

Article Published Date : Jul 05, 2024

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Prion Diseases

Pharmacological Actions : Neuroprotective Agents

[+]

Natural products may interfere With SARS-CoV-2 attachment to the host cell.May 04, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Biomol Struct Dyn. 2020 May 5:1-10. Epub 2020 May 5. PMID: 32340551

Article Published Date : May 04, 2020

Study Type : In Vitro Study

Additional Links

Substances : Alpha Linolenic Acid, Biochanin A, Caffeic Acid, Caffeic acid phenethyl ester, Chlorogenic Acid, Cinnamaldehyde, Formononetin, Genistein, Hydroxytyrosol, Thymoquinone

Diseases : Coronavirus Infection

Pharmacological Actions : Antiviral Agents

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Neuroprotective potential of caffeic acid phenethyl ester in CNS disorders.Jun 07, 2021

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Pubmed Data : Curr Neuropharmacol. 2021 Jun 8. Epub 2021 Jun 8. PMID: 34102977

Article Published Date : Jun 07, 2021

Study Type : Review

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Anxiety, Brain Injury: Traumatic, Depression, Epilepsy, Huntington Disease, Parkinson's Disease, Stroke

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

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Role of inflammation and oxidative stress in tissue damage associated with cystic fibrosis: CAPE as a future therapeutic strategy.Sep 15, 2021

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Pubmed Data : Mol Cell Biochem. 2021 Sep 16. Epub 2021 Sep 16. PMID: 34529223

Article Published Date : Sep 15, 2021

Study Type : Review

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Cystic Fibrosis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

The antibacterial effect of caffeic acid phenethyl ester on cariogenic bacteria and streptococcus mutans biofilms. Jun 14, 2020

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Pubmed Data : Antimicrob Agents Chemother. 2020 Jun 15. Epub 2020 Jun 15. PMID: 32540977

Article Published Date : Jun 14, 2020

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Steptococcus Mutans Infections

Pharmacological Actions : Antimicrobial

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The anticancer impacts of free and liposomal caffeic acid phenethyl ester (CAPE) on melanoma cell line (A375).Dec 17, 2023

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Pubmed Data : Cell Biochem Funct. 2023 Dec 18. Epub 2023 Dec 18. PMID: 38111127

Article Published Date : Dec 17, 2023

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Melanoma

Pharmacological Actions : Apoptotic

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The combination of CAPE and radiotherapy may be a potentially effective approach to increase the therapeutic window in lung cancer patients.Nov 21, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Radiother Oncol. 2023 Nov 22:110021. Epub 2023 Nov 22. PMID: 38000688

Article Published Date : Nov 21, 2023

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Lung Cancer

Pharmacological Actions : Radiosensitizer

[+]

The effect of caffeic acid phenethyl ester on cell cycle control gene expressions in breast cancer cells.Feb 28, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Biol Res Commun. 2021 Mar ;10(1):39-43. PMID: 33681396

Article Published Date : Feb 28, 2021

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative , Cell cycle arrest, Chemopreventive

[+]

The neuroprotective effects of caffeic acid phenethyl ester against methamphetamine-induced neurotoxicity.Jun 30, 2024

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ecotoxicol Environ Saf. 2024 Jul 1 ;279:116497. Epub 2024 May 27. PMID: 38805827

Article Published Date : Jun 30, 2024

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Amphetamine Addiction/Withdrawal, Neurodegenerative Diseases

Pharmacological Actions : Neuroprotective Agents

[+]

The results showed that the use of CAPE and stem cells in Parkinson rats caused a significant reduction in the apoptotic cells.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Basic Clin Neurosci. 2022 ;13(5):637-646. Epub 2022 Sep 1. PMID: 37313025

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Parkinson's Disease

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

[+]

The upregulation of caffeic acid phenethyl ester on growth differentiation factor 15 inhibits transforming growth factor β/Smad signaling in bladder carcinoma cells.Jul 06, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomedicines. 2022 Jul 7 ;10(7). Epub 2022 Jul 7. PMID: 35884930

Article Published Date : Jul 06, 2022

Study Type : In Vitro Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Bladder Cancer

Pharmacological Actions : Antiproliferative , Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Therapeutic efficacy of caffeic acid phenethyl ester in cancer therapy.Mar 16, 2023

Click here to read the entire abstract

Pubmed Data : Chem Biol Drug Des. 2023 Mar 17. Epub 2023 Mar 17. PMID: 36929632

Article Published Date : Mar 16, 2023

Study Type : Review

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Cancers: All

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Antiproliferative , Apoptotic

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View the Evidence: 172 Abstracts with Caffeic acid phenethyl ester Research

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Intrathecal CAPE following spinal cord injury decreases tissue and serum IL-6 levels as well as decreases spinal cord edema and microhemorrhage.Dec 31, 2017

Caffeic acid phenethyl ester could be effective for treating of periodontal diseases.Nov 06, 2016

Caffeic acid phenethyl ester inhibits cell proliferation and up-regulates the antioxidant levels in HSC-T6 cells.Feb 20, 2017

Caffeic acid phenethyl ester reduces the adverse effects of nicotine on the endometrium.Aug 31, 2023

Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT.Mar 12, 2024

Evaluation of efficacy of curcumin and caffeic acid phenethyl ester in breast cancer by preclinical studies.Mar 20, 2024

Role of CAPE in reducing oxidative stress in animal models with traumatic brain injury Aug 31, 2020

Aggressive mammary cancers lacking lymphocytic infiltration arise in irradiated mice and can be prevented by dietary intervention.Dec 11, 2019

Analysis of potential protective effects of caffeic acid phenethyl ester against gentamicin ototoxicity.Dec 31, 2021

Anti-glioma effects of Caffeic acid phenethyl ester and Dasatinib combination therapy in an in vivo glioma model.May 14, 2018

Attenuating effects of caffeic acid phenethyl ester and betaine on abamectin-induced hepatotoxicity and nephrotoxicity.Mar 26, 2018

Better neuroprotective profile of caffeic acid phenyl ester over resveratrol in non-traumatic ischemia-reperfusion injury of the spinal cord.Dec 08, 2021

Caffeic acid phenethyl ester (CAPE) has a protective effect on oxidative stress in rat liver exposed to the 900 MHz electromagnetic field.Jun 30, 2009

Caffeic acid phenethyl ester alleviated hypouricemia in hyperuricemic mice through inhibiting XOD and up-regulating OAT3.Jul 31, 2022

Caffeic acid phenethyl ester alleviates airway inflammation and remodelling in chronic asthma by balancing the airway microenvironment.Oct 12, 2016

Caffeic acid phenethyl ester ameliorates imidacloprid-induced acute toxicity in the rat cerebral cortex.Sep 29, 2022

Caffeic acid phenethyl ester ameliorates metabolic disease by inducing PPARγ activity and adipose tissue remodelling.Mar 04, 2018

Caffeic acid phenethyl ester ameliorates pulmonary inflammation and apoptosis reducing Nf-κβ activation in blunt pulmonary contusion model.Jul 31, 2019

Caffeic acid phenethyl ester ameliorates titanium particle-induced bone loss and inflammatory reaction.Nov 11, 2023

Caffeic acid phenethyl ester attenuates dextran sulfate sodium-induced ulcerative colitis.Feb 28, 2022

Caffeic acid phenethyl ester attenuates indomethacin-induced gastric ulcer.Sep 22, 2023

Caffeic acid phenethyl ester attenuates liver fibrosis.Feb 09, 2017

Caffeic acid phenethyl ester attenuates neuropathic pain.Dec 31, 2017

Caffeic acid phenethyl ester attenuates paclitaxel-induced peripheral neuropathyAug 28, 2022

Caffeic acid phenethyl ester can ameliorate on insulin resistance through modulation of JNK and NF-κB signalling pathway in mice and HepG2 cells.Aug 10, 2017

Caffeic acid phenethyl ester can demonstrate protective effects on endothelial damage, inflammation and oxidative stress axis.Jun 29, 2020

Caffeic acid phenethyl ester could attenuate the effects of chronic renal failure.Dec 26, 2021

Caffeic acid phenethyl ester could be considered as a promising neuroprotective agent against progressive neurodegenerative diseases.Jul 31, 2018

Caffeic acid phenethyl ester could be used for supportive and protective therapy against pesticide intoxication.Jun 29, 2016

Caffeic acid phenethyl ester counteracts doxorubicin-induced chemobrain.Dec 14, 2020

Caffeic acid phenethyl ester guards against benign prostate hypertrophy.Mar 29, 2018

Caffeic acid phenethyl ester has a preventive effect on early brain injury after subarachnoid hemorrhage.Mar 17, 2020

Caffeic acid phenethyl ester has a protective effect against sevoflurane induced neurotoxicity in neonatal rats.Aug 03, 2016

Caffeic acid phenethyl ester increased NDRG1 expression through phosphorylation of ERK1/2 to repress oral squamous cell carcinoma cells growth.Feb 08, 2017

Caffeic acid phenethyl ester inhibits neuro-inflammation and oxidative stress following spinal cord injury.Mar 24, 2024

Caffeic acid phenethyl ester inhibits the growth of bladder carcinoma cells by upregulating growth differentiation factor 15.Oct 14, 2021

Caffeic acid phenethyl ester inhibits the progression of ovarian cancer.Feb 28, 2018

Caffeic acid phenethyl ester is an effective antitumor agent for human androgen-dependent and -independent prostate carcinoma cells.Jan 05, 2022

Caffeic acid phenethyl ester is effective in resolving colon fibrosis in chronic inflammation.Aug 23, 2018

Caffeic acid phenethyl ester is protective in experimental ulcerative colitisMay 19, 2017

Caffeic acid phenethyl ester loaded PEG-PLGA nanoparticles enhance wound healing in diabetic rats.Dec 26, 2022

Caffeic acid phenethyl ester may be a potential therapeutic agent for patients with advanced PCa.May 14, 2016

Caffeic acid phenethyl ester may be protective against damage caused by cisplatin in the testicles.Jul 05, 2020

Caffeic acid phenethyl ester may play an important role in the regulation of cardiac hypertrophy induced by pressure overload.Apr 23, 2017

Caffeic acid phenethyl ester mitigates cadmium-induced hepatotoxicity.Dec 31, 2020

Caffeic acid phenethyl ester mitigates cognitive impairment in aged mice following anesthesia and surgery.Mar 12, 2023

Caffeic acid phenethyl ester mitigates infertility: A crucial role of metalloproteinase and angiogenic factor in cadmium-induced testicular damage.Nov 16, 2021

Caffeic Acid Phenethyl Ester prevented HFCS-induced cardiovascular abnormalities.Dec 31, 2015

Caffeic acid phenethyl ester prevented the neurodegenerations in brain tissue in chlorpyrifos induced Parkinson's disease.Dec 31, 2017

Caffeic acid phenethyl ester promotes wound healing of mice pressure ulcers.May 31, 2018

Caffeic acid phenethyl ester protects against photothrombotic cortical ischemic injury in mice.Dec 31, 2017

Caffeic acid phenethyl ester protects kidney mitochondria against ischemia/reperfusion induced injury.May 07, 2021

Caffeic acid phenethyl ester protects the brain against hexavalent chromium toxicity.Apr 28, 2017

Caffeic acid phenethyl ester reduces ischemia-induced kidney mitochondrial injury in rats.Dec 31, 2016

Caffeic acid phenethyl ester reduces pro inflammatory cytokines.Dec 31, 2020

Caffeic acid phenethyl ester rescued streptozotocin-induced memory loss.Feb 23, 2018

Caffeic acid phenethyl ester rescues pulmonary arterial hypertension.Mar 21, 2019

Caffeic acid phenethyl ester reversed cadmium-induced cell death in hippocampus and cortex and subsequent cognitive disorders.Sep 30, 2020

Caffeic acid phenethyl ester should be considered in the prevention of oxidative stress in diabetic liver.Dec 31, 2015

Caffeic acid phenethyl ester treatment ameliorates oxidative stress in the serum and liver in a rat model of acute methanol intoxication.Apr 29, 2016

Caffeic acid phenethyl ester treatment provided protection against fluoxetine toxicity.Dec 31, 2015

Caffeic acid phenethyl ester, a coffee polyphenol, inhibits DNA methylation in vitro and in vivo.Nov 14, 2020

Caffeic acid phenethyl ester, a compound found within propolis causes regression of experimental endometriosis.Apr 01, 2007

Caffeic acid phenetyl ester, a compound found within bee propolis, protects against doxorubucin-induced cardiotoxicity in rats. Sep 30, 2010

Caffeic acid phenetyl ester, a compound found within bee propolis, protects the diabetic heart against oxidative stress. Feb 01, 2005

Caffeic acid phenyl ester could have an important role in otitis media treatment.Apr 30, 2017

Caffeic acid's role in mitigating polycystic ovary syndrome.Sep 30, 2023

CAPE seems to be effective agent and may be related to its potent antioxidant, anti-inflammatory properties and action as an Nrf2 activator.Aug 31, 2017

Comparison of the protective effects of curcumin and caffeic acid phenethyl ester against doxorubicin-induced testicular toxicity.Nov 30, 2020

Curcumin and caffeic acid phenethyl ester decrease intestinal tumors in an animal model of familial adenomatous polyposis.May 01, 2000

Curcumin and CAPE may reduce chemotherapy-induced mucosal barrier injury. Feb 01, 2004

Effects of caffeic acid phenethyl ester in reducing cerebral edema.Aug 31, 2020

Caffeic acid phenethyl ester

View the Evidence:
172 Abstracts with Caffeic acid phenethyl ester Research