Caffeine

Name	AC	CK
Athletic Performance	6	71
Obesity	8	57
Alzheimer's Disease	8	27
Cognitive Decline/Dysfunction	4	22
Insulin Resistance	3	21
Athletic Performance: Recovery	1	20
Basal Cell Carcinoma	1	20
Breast Cancer	2	20
Cortisol: High	2	20
Fatigue: Excercise-Induced	2	20
Cellulite	4	16
Aging	2	12
Diabetes Mellitus: Type 2	2	12
Lipopolysaccharide-Induced Toxicity	2	12
Apnea	1	10
Breast Cancer: Estrogen	1	10
Chemotherapy-Induced Toxicity: Cisplatin	1	10
Depression	1	10
Endotoxemia	1	10
Hyperlipidemia	1	10
Lung Cancer	1	10
Malignant Melanoma	1	10
Melanoma	1	10
Migraine Disorders	1	10
Muscle Fatigue	1	10
Obsessive-Compulsive Disorder	1	10
Overweight	1	10
Testosterone: Too Low	1	10
Aluminum Toxicity	3	6
Depression	3	6
Brain Inflammation	3	5
Cataract	3	5
Neurodegenerative Diseases	3	4
Nonalcoholic fatty liver disease (NAFLD)	2	4
Anxiety	2	3
Liver Cancer	3	3
Parkinson's Disease	2	3
Pertussis	1	3
Whooping Cough	1	3
Amnesia	1	2
Chemically-Induced Liver Damage	1	2
Colon Cancer	1	2
DNA damage	1	2
Dementia	2	2
Diabetes Mellitus: Type 1	1	2
Drug-Induced Toxicity: Epilepsy Drugs	1	2
Encephalopathy	1	2
Fatigue	1	2
H1N1 Infection	1	2
High Fat Diet	1	2
High Fructose Diet	1	2
Immune Disorders: Low Immune Function	1	2
Influenza A	1	2
Kidney Damage: Chemically-Induced	1	2
Oxidative Stress	1	2
Radiation Induced Illness	1	2
Testicular Injury: Cadmium-Induced	1	2
Diabetic Complications	1	1
Dopamine Deficiency	1	1
Glaucoma	1	1
Heavy Metal Toxicity	1	1
Kidney Cancer	1	1
Memory Disorders	1	1
Metabolic Diseases	1	1
Pseudomonas aeruginosa	1	1
Ultraviolet Radiation Induced Damage	1	1

Name	AC	CK
Chemopreventive	6	44
Neuroprotective Agents	18	35
Antioxidants	11	26
Antidepressive Agents	4	16
Apoptotic	3	13
Antiproliferative	3	12
Anti-Tumor	1	10
Antineoplastic Agents	1	10
Cell cycle arrest	1	10
Chemosensitizer	1	10
Estrogen Receptor Modulators	1	10
Insulin-Like Growth Factor Inhibition/Downregulation	1	10
Pancreato Protective Agents	1	10
Anti-Inflammatory Agents	3	6
Brain-derived neurotrophic factor modulator	2	4
Hepatoprotective	2	4
Renoprotective	2	4
Anti-Anxiety Agents	1	2
Antimutagenic Agents	1	2
Bcl-2 protein down-regulation	1	2
Genoprotective	1	2
Lipolytic	1	2
Radioprotective	1	2
Tumor Suppressor Protein p53 Upregulation	1	2
Viral Hemagglutinin Inhibitor	1	2
Antimicrobial	1	1
Dopaminergic	1	1
Nootropic Agents	1	1
Nrf2 activation	1	1
Photoprotective	1	1
Regenerative	1	1

[+]

Acute caffeine supplementation is highly ergogenic for movement velocity in resistance exercise.Oct 22, 2019

Click here to read the entire abstract

Pubmed Data : Sports Med. 2019 Oct 23. Epub 2019 Oct 23. PMID: 31643020

Article Published Date : Oct 22, 2019

Study Type : Meta Analysis, Review

Additional Links

Substances : Caffeine

Diseases : Athletic Performance

Therapeutic Actions : Exercise: Resistance Training

[+]

Caffeine supplementation showed a significant ergogenic effect on muscle endurance and maximum strength in the bench press exercise.Jun 17, 2020

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Pubmed Data : Crit Rev Food Sci Nutr. 2020 Jun 18:1-14. Epub 2020 Jun 18. PMID: 32551869

Article Published Date : Jun 17, 2020

Study Type : Meta Analysis, Review

Additional Links

Substances : Caffeine

Diseases : Athletic Performance

Therapeutic Actions : Exercise

[+]

Coffee intake appears to exert a moderate protective effect against basal cell cancer development.Jul 06, 2016

Click here to read the entire abstract

Pubmed Data : Eur J Nutr. 2016 Jul 7. Epub 2016 Jul 7. PMID: 27388462

Article Published Date : Jul 06, 2016

Study Type : Meta Analysis, Review

Additional Links

Substances : Caffeine, Coffee

Diseases : Basal Cell Carcinoma

Pharmacological Actions : Chemopreventive

[+]

Ergogenic effects of acute caffeine intake on muscular endurance and muscular strength in women.May 26, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Environ Res Public Health. 2021 May 27 ;18(11). Epub 2021 May 27. PMID: 34072182

Article Published Date : May 26, 2021

Study Type : Meta Analysis

Additional Links

Substances : Caffeine

Diseases : Athletic Performance: Recovery

Therapeutic Actions : Exercise

[+]

Pre-exercise intake of a moderate dose of caffeine may effectively increase fat utilization during aerobic exercise.Nov 23, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2020 Nov 24 ;12(12). Epub 2020 Nov 24. PMID: 33255240

Article Published Date : Nov 23, 2020

Study Type : Meta Analysis, Review

Additional Links

Substances : Caffeine

Diseases : Obesity

Additional Keywords : Anti-Obesity Agents

[+]

A combination of 500-mg G-hesperidin and 75-mg caffeine for 12 weeks significantly reduced abdominal fat.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr J. 2016 ;15(1):6. Epub 2016 Jan 19. PMID: 26786000

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Caffeine, Hesperidin

Diseases : Obesity

Additional Keywords : Anti-Obesity Agents

[+]

Blood dopamine level enhanced by caffeine in men after treadmill running.Oct 31, 2019

Click here to read the entire abstract

Pubmed Data : Chin J Physiol. 2019 Nov-Dec;62(6):279-284. PMID: 31793465

Article Published Date : Oct 31, 2019

Study Type : Human Study

Additional Links

Substances : Caffeine

Diseases : Fatigue: Excercise-Induced

Therapeutic Actions : Exercise

[+]

Caffeinated chewing gum increases repeated sprint performance and augments increases in testosterone in competitive cyclists.Dec 01, 2010

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Pubmed Data : Eur J Appl Physiol. 2010 Dec;110(6):1243-50. Epub 2010 Aug 25. PMID: 20737165

Article Published Date : Dec 01, 2010

Study Type : Human Study

Additional Links

Substances : Caffeine

Diseases : Athletic Performance, Cortisol: High, Testosterone: Too Low

Therapeutic Actions : Exercise: Cycling

[+]

Caffeinated chewing gums and gels may enhance resistance exercise performance even when consumed 10 min before exercise.Jul 21, 2021

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Pubmed Data : Sports Med. 2021 Jul 22. Epub 2021 Jul 22. PMID: 34291426

Article Published Date : Jul 21, 2021

Study Type : Human Study

Additional Links

Substances : Caffeine

Diseases : Athletic Performance

Therapeutic Actions : Exercise: Resistance Training

[+]

Caffeine compares favorably to amphetamine in reducing the symptoms of treatment-resistant obsessive-compulsive disorder.Nov 01, 2009

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Pubmed Data : J Clin Psychiatry. 2009 Nov;70(11):1530-5. Epub 2009 Jun 30. PMID: 19573497

Article Published Date : Nov 01, 2009

Study Type : Human Study

Additional Links

Substances : Caffeine

Diseases : Obsessive-Compulsive Disorder

Additional Keywords : Natural Substances Versus Drugs

[+]

Caffeine consumption appears to be associated with higher levels of physical activity in Japanese women.Feb 05, 2018

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Pubmed Data : Int J Sport Nutr Exerc Metab. 2018 Feb 6:1-18. Epub 2018 Feb 6. PMID: 29405779

Article Published Date : Feb 05, 2018

Study Type : Human Study

Additional Links

Substances : Caffeine

Additional Keywords : Physical Activity

[+]

Caffeine exerted a positive effect on time to exhaustion at MLSS workload that was accompanied by shifts in substrate utilization during exercise.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2015 ;7(7):5254-64. Epub 2015 Jun 30. PMID: 26133971

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : Caffeine

Therapeutic Actions : Exercise: Cycling

[+]

Caffeine given at breakfast significantly stimulated ketone production in a dose-dependent manner.Nov 24, 2016

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Pubmed Data : Can J Physiol Pharmacol. 2016 Nov 25. Epub 2016 Nov 25. PMID: 28177691

Article Published Date : Nov 24, 2016

Study Type : Human Study

Additional Links

Substances : Caffeine

Diseases : Alzheimer's Disease

Additional Keywords : Dose Response

[+]

Caffeine improves muscular endurance and aerobic performance in adolescent athletes.Jun 14, 2020

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Pubmed Data : Scand J Med Sci Sports. 2020 Jun 15. Epub 2020 Jun 15. PMID: 32538495

Article Published Date : Jun 14, 2020

Study Type : Human Study

Additional Links

Substances : Caffeine

Diseases : Athletic Performance

Therapeutic Actions : Exercise

[+]

Caffeine in coffee can prevent and help brain function in Alzheimer's DiseaseSep 01, 2009

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Curr Neuropharmacol. 2009 Sep ;7(3):207-16. PMID: 20190962

Article Published Date : Sep 01, 2009

Study Type : Human Study, Review, Transgenic Animal Study

Additional Links

Substances : Caffeine, Coffee

Diseases : Alzheimer's Disease

[+]

Caffeine increases the secretion of cortisol. Sep 01, 2005

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Pubmed Data : Psychosom Med. 2005 Sep-Oct;67(5):734-9. PMID: 16204431

Article Published Date : Sep 01, 2005

Study Type : Human Study

Additional Links

Substances : Caffeine

Diseases : Cortisol: High

[+]

Caffeine ingestion attenuates fatigue-induced loss of muscle torque complexity.Oct 02, 2017

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Pubmed Data : Med Sci Sports Exerc. 2017 Oct 3. Epub 2017 Oct 3. PMID: 28991045

Article Published Date : Oct 02, 2017

Study Type : Human Study

Additional Links

Substances : Caffeine

Diseases : Fatigue: Excercise-Induced, Muscle Fatigue

Therapeutic Actions : Exercise

[+]

Caffeine intake was related to moderately better cognitive maintenance over 5 years in older women with vascular disorders.Dec 31, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Alzheimers Dis. 2013 ;35(2):413-21. PMID: 23422357

Article Published Date : Dec 31, 2012

Study Type : Human Study

Additional Links

Substances : Caffeine

Diseases : Aging, Cognitive Decline/Dysfunction

[+]

Caffeine is as effective as aminophylline, while it is superior to aminophylline regarding its overall safety.Dec 31, 2017

Click here to read the entire abstract

Pubmed Data : Yakugaku Zasshi. 2018 ;138(2):237-242. PMID: 29386437

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Substances : Caffeine

Diseases : Apnea

Additional Keywords : Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs

[+]

Caffeine may play a protective role in T2DM via increased beta cell function.Jun 14, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2020 Jun 15 ;12(6). Epub 2020 Jun 15. PMID: 32549382

Article Published Date : Jun 14, 2020

Study Type : Human Study

Additional Links

Substances : Caffeine

Diseases : Diabetes Mellitus: Type 2, Insulin Resistance

Pharmacological Actions : Pancreato Protective Agents

[+]

Caffeine optimizes HIIT benefits on obesity-associated metabolic adversity in women.Jul 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Med Sci Sports Exerc. 2020 Aug ;52(8):1793-1800. PMID: 32079912

Article Published Date : Jul 31, 2020

Study Type : Human Study

Additional Links

Substances : Caffeine

Diseases : Endotoxemia, Lipopolysaccharide-Induced Toxicity, Obesity

[+]

Caffeine potentiates chemotherapy for metastatic osteosarcoma.Sep 01, 2009

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Pubmed Data : J Orthop Sci. 2009 Sep;14(5):556-65. Epub 2009 Oct 3. PMID: 19802667

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Substances : Caffeine

Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Lung Cancer

Pharmacological Actions : Antineoplastic Agents, Chemosensitizer

Additional Keywords : Drug: Doxorubicin, Drug Synergy

[+]

Caffeine results in explicit memory enhancement for young adults during the early morning.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Psychol. 2016 ;7:1764. Epub 2016 Nov 14. PMID: 27895607

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Caffeine, Coffee

[+]

Coffee and caffeine may be associated with improved capacity to efficiently repair DNA damage.Dec 31, 2014

Click here to read the entire abstract

Pubmed Data : J Nutrigenet Nutrigenomics. 2015 ;8(4-6):174-84. Epub 2015 Dec 16. PMID: 26670362

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : Caffeine, Coffee

Diseases : Breast Cancer

Pharmacological Actions : Chemopreventive

[+]

consumption of caffeinated coffee was inversely associated with melanoma risk among men.Feb 19, 2017

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Pubmed Data : Int J Cancer. 2017 Feb 20. Epub 2017 Feb 20. PMID: 28218395

Article Published Date : Feb 19, 2017

Study Type : Human Study

Additional Links

Substances : Caffeine, Coffee

Diseases : Melanoma

Additional Keywords : Risk Reduction

[+]

Daily caffeine intake reduces insulin sensitivity. Dec 01, 2007

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Pubmed Data : Metabolism. 2007 Dec;56(12):1694-8. PMID: 17998023

Article Published Date : Dec 01, 2007

Study Type : Human Study

Additional Links

Substances : Caffeine

Diseases : Insulin Resistance

[+]

Implementing a caffeine-EGCG-containing drink prior to exercise may improve muscle mass, fitness, and lipid profiles in overweight women.Oct 01, 2010

Click here to read the entire abstract

Pubmed Data : Appl Physiol Nutr Metab. 2010 Oct;35(5):607-16. PMID: 20962916

Article Published Date : Oct 01, 2010

Study Type : Human Study

Additional Links

Substances : Caffeine, Catechin

Diseases : Hyperlipidemia, Obesity, Overweight

Pharmacological Actions : Antioxidants

[+]

Increasing caffeine intake and caffeinated coffee consumption is associated with decreased risk of cutaneous malignant melanomas.Jul 09, 2015

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Pubmed Data : Epidemiology. 2015 Jul 10. Epub 2015 Jul 10. PMID: 26172864

Article Published Date : Jul 09, 2015

Study Type : Human Study

Additional Links

Substances : Caffeine, Coffee

Diseases : Malignant Melanoma

Additional Keywords : Risk Reduction

[+]

Ingesting matcha with caffeine improves both attention and work performance when suffering from psychological stress.May 16, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2021 May 17 ;13(5). Epub 2021 May 17. PMID: 34067795

Article Published Date : May 16, 2021

Study Type : Human Study

Additional Links

Substances : Caffeine, Green Tea

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

Low dose of caffeine enhances the efficacy of antidepressants in major depressive disorder.Jan 04, 2017

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Pubmed Data : Mol Nutr Food Res. 2017 Jan 5. Epub 2017 Jan 5. PMID: 28054436

Article Published Date : Jan 04, 2017

Study Type : Human Study

Additional Links

Substances : Caffeine

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Antidepressive Agents, caffeine, Depression

Problem Substances : Antidepressants

[+]

Moderate coffee intake was associated with smaller invasive primary tumors and lower proportions of ER positive tumors compared with patients with low consumption.Feb 16, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Cancer Res. 2015 Feb 17. Epub 2015 Feb 17. PMID: 25691730

Article Published Date : Feb 16, 2015

Study Type : Human Study

Additional Links

Substances : Caffeic Acid, Caffeine

Diseases : Breast Cancer, Breast Cancer: Estrogen

Pharmacological Actions : Anti-Tumor, Antiproliferative , Apoptotic, Cell cycle arrest, Chemopreventive, Estrogen Receptor Modulators, Insulin-Like Growth Factor Inhibition/Downregulation

Additional Keywords : Dose Response, Risk Reduction

Problem Substances : Tamoxifen

[+]

Tea catechin and caffeine activate brown adipose tissue and increase cold-induced thermogenic capacity in humans.Mar 31, 2017

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2017 Apr ;105(4):873-881. Epub 2017 Mar 8. PMID: 28275131

Article Published Date : Mar 31, 2017

Study Type : Human Study

Additional Links

Substances : Caffeine, Catechin , Tea

Additional Keywords : Plant Extracts

[+]

Tryptophan, Niacin, Calcium, and Caffeine may have therapeutic value in the treatment of migraines. Jan 01, 2001

Click here to read the entire abstract

Pubmed Data : Med Hypotheses. 2001 Jan;56(1):91-4. PMID: 11133261

Article Published Date : Jan 01, 2001

Study Type : Human Study

Additional Links

Substances : Caffeine, Calcium, Niacin, Tryptophan

Diseases : Migraine Disorders

[+]

Vitamin A (retinol), caffeine and ruscogenine have anti-cellulite properties.Jul 01, 2001

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Pubmed Data : J Cosmet Sci. 2001 Jul-Aug;52(4):199-210. PMID: 11479653

Article Published Date : Jul 01, 2001

Study Type : Human Study

Additional Links

Substances : Caffeine, Ruscogenine, Vitamin A

Diseases : Cellulite

[+]

Caffeine might improve outcomes in pertussis by preventing apnoea and decreasing pulmonary complications.Mar 27, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMJ Case Rep. 2018 Mar 28 ;2018. Epub 2018 Mar 28. PMID: 29592985

Article Published Date : Mar 27, 2018

Study Type : Human: Case Report

Additional Links

Substances : Caffeine

Diseases : Pertussis, Whooping Cough

Additional Keywords : Risk Reduction

[+]

A combination of caffeine, arginine, soy isoflavones, and L-carnitine enhances both lipolysis and fatty acid oxidation in animal model of obesity. Oct 01, 2007

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Pubmed Data : J Nutr. 2007 Oct;137(10):2252-7. PMID: 17885007

Article Published Date : Oct 01, 2007

Study Type : Animal Study

Additional Links

Substances : Arginine, Caffeine, Carnitine, Isoflavones

Diseases : Obesity

Pharmacological Actions : Lipolytic

Additional Keywords : Anti-Obesity Agents

[+]

Advancing combination treatment with cilostazol and caffeine for Alzheimer's disease in high fat-high fructose-STZ induced model of amnesia.Mar 09, 2022

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Pubmed Data : Eur J Pharmacol. 2022 Mar 10 ;921:174873. Epub 2022 Mar 10. PMID: 35283111

Article Published Date : Mar 09, 2022

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Alzheimer's Disease, Amnesia, High Fat Diet, High Fructose Diet

Pharmacological Actions : Neuroprotective Agents

[+]

Alpha-tocopherol treatment is able to inhibit oxidative stress and anxiety-like behaviour evoked by caffeine.Dec 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oxid Med Cell Longev. 2019 ;2019:8419810. Epub 2019 Oct 21. PMID: 31772712

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Caffeine, Vitamin E: alpha tocopherol

Diseases : Anxiety, Oxidative Stress

Pharmacological Actions : Anti-Anxiety Agents, Antioxidants

Additional Keywords : Risk Reduction

[+]

Caffeine actually protected mice from genotoxicity and mutagenicity attributed to aging.May 18, 2017

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Pubmed Data : J Toxicol Environ Health A. 2017 May 19:1-9. Epub 2017 May 19. PMID: 28524728

Article Published Date : May 18, 2017

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Aging, DNA damage

Pharmacological Actions : Antimutagenic Agents, Genoprotective

Additional Keywords : Aging, Antimutagenic Agents, caffeine, DNA damage, Genoprotective

[+]

Caffeine and antioxidants have the ability to reverse cadmium-induced testicular injury.Dec 27, 2020

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Pubmed Data : Andrologia. 2020 Dec 28:e13948. Epub 2020 Dec 28. PMID: 33372294

Article Published Date : Dec 27, 2020

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Testicular Injury: Cadmium-Induced

Pharmacological Actions : Antioxidants

[+]

Caffeine and EGCG alleviate high-trans fatty acid and high-carbohydrate diet-induced NASH.Dec 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Nutr. 2021 ;8:784354. Epub 2021 Nov 22. PMID: 34881283

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Caffeine, EGCG (Epigallocatechin gallate)

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

Caffeine and lycopene provided protective effects against experimentally induced diabetes mellitus.Sep 23, 2015

Click here to read the entire abstract

Pubmed Data : Pancreas. 2015 Sep 24. Epub 2015 Sep 24. PMID: 26418913

Article Published Date : Sep 23, 2015

Study Type : Animal Study

Additional Links

Substances : Caffeine, Lycopene

Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2

Additional Keywords : Risk Reduction

[+]

Caffeine demonstrates anti-influenza activity. May 01, 2003

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Pubmed Data : Clin Ther. 2003 May;25(5):1429-39. PMID: 4002618

Article Published Date : May 01, 2003

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : H1N1 Infection, Influenza A

Pharmacological Actions : Viral Hemagglutinin Inhibitor

[+]

Caffeine exhibits radioprotective properties in whole-body irradiated male mice.Mar 01, 2003

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Pubmed Data : In Vivo. 2003 Mar-Apr;17(2):197-200. PMID: 12792986

Article Published Date : Mar 01, 2003

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Radiation Induced Illness

Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Radioprotective, Tumor Suppressor Protein p53 Upregulation

[+]

Caffeine may abrogate lipopolysaccharide-induced oxidative stress and neuroinflammation.Nov 07, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomolecules. 2019 Nov 8 ;9(11). Epub 2019 Nov 8. PMID: 31717470

Article Published Date : Nov 07, 2019

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

[+]

Caffeine plus haloperidol reduces fatigue in an experimental model of Parkinson's disease.Mar 14, 2023

Click here to read the entire abstract

Pubmed Data : Purinergic Signal. 2023 Mar 15. Epub 2023 Mar 15. PMID: 36918462

Article Published Date : Mar 14, 2023

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Fatigue, Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Caffeine prevents neurodegeneration and behavioral alterations in a mice model of agitated depression.Nov 08, 2019

Click here to read the entire abstract

Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2019 Nov 9 ;98:109776. Epub 2019 Nov 9. PMID: 31707092

Article Published Date : Nov 08, 2019

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Depression, Neurodegenerative Diseases

Pharmacological Actions : Antidepressive Agents, Neuroprotective Agents

[+]

Caffeine prevents UV-B induced cataract formation in mice. Jul 03, 2009

Click here to read the entire abstract

Pubmed Data : Life Sci. 2009 Jul 3;85(1-2):77-84. Epub 2009 May 7. PMID: 18788993

Article Published Date : Jul 03, 2009

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Cataract

[+]

Caffeine promotes conversion of palmitic acid to palmitoleic acid.Dec 31, 2017

Click here to read the entire abstract

Pubmed Data : Front Pharmacol. 2018 ;9:321. Epub 2018 Apr 6. PMID: 29681853

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Caffeine, Palmitic acid , Palmitoleic acid

[+]

Caffeine protects against stress-induced murine depression.Jan 30, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2021 03 31 ;11(1):7287. Epub 2021 Mar 31. PMID: 33790369

Article Published Date : Jan 30, 2021

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Caffeine provides a significant neuroprotection against aluminum chloride induced neurotoxicity.Mar 06, 2018

Click here to read the entire abstract

Pubmed Data : Nutr Neurosci. 2018 Mar 7:1-8. Epub 2018 Mar 7. PMID: 29514562

Article Published Date : Mar 06, 2018

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Aluminum Toxicity

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Aluminum Chloride

[+]

Caffeine, vanillin, and their combination could potentially be an effective regimen in managing AlCl3-induced renal toxicity.Dec 31, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biochem Res Int. 2023 ;2023:6615863. Epub 2023 Aug 22. PMID: 37649570

Article Published Date : Dec 31, 2022

Study Type : Animal Study

Additional Links

Substances : Caffeine, Vanillin

Diseases : Aluminum Toxicity , Kidney Damage: Chemically-Induced

Pharmacological Actions : Antioxidants, Renoprotective

Additional Keywords : Natural Substance Synergy

Problem Substances : Aluminum

[+]

Chronic caffeine consumption has a potentially good protective effect against Alzheimer's disease.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Clin Exp Pathol. 2015 ;8(7):7710-28. Epub 2015 Jul 1. PMID: 26339337

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Aluminum Toxicity

Pharmacological Actions : Brain-derived neurotrophic factor modulator, Neuroprotective Agents

Problem Substances : Aluminum Chloride

[+]

Coadministration of epigallocatechin-3-gallate and caffeine in low dose ameliorates obesity and nonalcoholic fatty liver disease in obese rats.Feb 10, 2019

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Pubmed Data : Phytother Res. 2019 Feb 11. Epub 2019 Feb 11. PMID: 30746789

Article Published Date : Feb 10, 2019

Study Type : Animal Study

Additional Links

Substances : Caffeine, EGCG (Epigallocatechin gallate)

Diseases : Nonalcoholic fatty liver disease (NAFLD), Obesity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Anti-Obesity Agents

[+]

Crude caffeine reduces memory impairment and amyloidβ(1-42) levels in an Alzheimer's mouse model.Nov 30, 2012

Click here to read the entire abstract

Pubmed Data : Food Chem. 2012 Dec 1 ;135(3):2095-102. Epub 2012 Jun 29. PMID: 22953961

Article Published Date : Nov 30, 2012

Study Type : Transgenic Animal Study

Additional Links

Substances : Caffeine

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Plant Extracts

[+]

Effects of epigallocatechin gallate, caffeine, and their combination on fat accumulation in high-glucose diet-fed Caenorhabditis elegans.Jul 23, 2023

Click here to read the entire abstract

Pubmed Data : Biosci Biotechnol Biochem. 2023 Jul 24 ;87(8):898-906. PMID: 37363872

Article Published Date : Jul 23, 2023

Study Type : Animal Study

Additional Links

Substances : Caffeine, EGCG (Epigallocatechin gallate)

Diseases : Obesity

Additional Keywords : Anti-Obesity Agents

[+]

Effects of photobiomodulation and caffeine treatment on acute kidney injury in a hypoxic ischemic neonatal rat model.Jul 31, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Physiol Rep. 2023 Aug ;11(15):e15773. PMID: 37549967

Article Published Date : Jul 31, 2023

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Encephalopathy

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Renoprotective

[+]

Long-term caffeine consumption reverses tumor-induced suppression of the innate immune response in adult mice. Dec 01, 2008

Click here to read the entire abstract

Pubmed Data : Planta Med. 2008 Dec;74(15):1779-84. Epub 2008 Nov 18. PMID: 19016405

Article Published Date : Dec 01, 2008

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Immune Disorders: Low Immune Function

[+]

Low doses of caffeine exert a hepatoprotective effect against carbon tetrachloride induced liver damage in rats.Aug 01, 2016

Click here to read the entire abstract

Pubmed Data : J Diet Suppl. 2016 Aug 2:1-15. Epub 2016 Aug 2. PMID: 27485995

Article Published Date : Aug 01, 2016

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Hepatoprotective

[+]

Phenobarbital-induced adverse effects could be reduced by a co-treatment with caffeine.Jun 21, 2017

Click here to read the entire abstract

Pubmed Data : Neurotox Res. 2017 Jun 22. Epub 2017 Jun 22. PMID: 28643232

Article Published Date : Jun 21, 2017

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Drug-Induced Toxicity: Epilepsy Drugs

Pharmacological Actions : Neuroprotective Agents

[+]

Pyrocatechol acts as an antioxidant together with caffeine to prevent cataract formation.Jan 26, 2017

Click here to read the entire abstract

Pubmed Data : Curr Eye Res. 2017 Jan 27:1-7. Epub 2017 Jan 27. PMID: 28128997

Article Published Date : Jan 26, 2017

Study Type : Animal Study

Additional Links

Substances : Caffeine, Coffee

Diseases : Cataract

Pharmacological Actions : Antioxidants

Additional Keywords : Risk Reduction

[+]

Remedial effects of caffeine against depressive-like behaviour in mice by modulation of neuroinflammation and BDNF.Apr 04, 2021

Click here to read the entire abstract

Pubmed Data : Nutr Neurosci. 2021 Apr 5:1-9. Epub 2021 Apr 5. PMID: 33814004

Article Published Date : Apr 04, 2021

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Brain Inflammation , Depression

Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Brain-derived neurotrophic factor modulator

[+]

Topica sulfo-carrabiose and caffeine have anti-cellulite properties.Aug 30, 2010

Click here to read the entire abstract

Pubmed Data : Int J Cosmet Sci. 2010 Aug 30. Epub 2010 Aug 30. PMID: 20807262

Article Published Date : Aug 30, 2010

Study Type : Animal Study

Additional Links

Substances : Caffeine, Sulfo-carrabiose

Diseases : Cellulite

[+]

Topical caffeine appears to contribute to reducing cellulite.Mar 01, 2008

Click here to read the entire abstract

Pubmed Data : J Cosmet Dermatol. 2008 Mar;7(1):23-9. PMID: 18254807

Article Published Date : Mar 01, 2008

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Cellulite

[+]

Topical caffeine may have a therapeutic role in cellulite reduction.Sep 01, 2008

Click here to read the entire abstract

Pubmed Data : J Cosmet Dermatol. 2008 Sep;7(3):232-7. PMID: 18789063

Article Published Date : Sep 01, 2008

Study Type : Animal Study

Additional Links

Substances : Caffeine

Diseases : Cellulite

[+]

White Tea, Green Tea, EGCG (Epigallocatechin gallate), and Caffeine inhibit colon cancer progression. Jan 01, 2007

Click here to read the entire abstract

Pubmed Data : Nutr Cancer. 2007;58(1):60-5. PMID: 17571968

Article Published Date : Jan 01, 2007

Study Type : Animal Study

Additional Links

Substances : Caffeine, EGCG (Epigallocatechin gallate), Green Tea, White Tea

Diseases : Colon Cancer

Pharmacological Actions : Chemopreventive

[+]

A comprehensive review of complementary and alternative treatments for alopecia. Jan 31, 2019

Click here to read the entire abstract

Pubmed Data : Skin Appendage Disord. 2019 Feb ;5(2):72-89. Epub 2018 Aug 21. PMID: 30815439

Article Published Date : Jan 31, 2019

Study Type : Review

Additional Links

Substances : Caffeine, Cystine, Melatonin, Methionine, Procyanidin B2 , Rosemary, Saw Palmetto, Vitamin B12, Vitamin C, Vitamin D, Zinc

Therapeutic Actions : Acupuncture, Magnet Therapy

[+]

A review of in vitro and vivo antihepatocarcinogenic effects of natural compounds. Jul 31, 2011

Click here to read the entire abstract

Pubmed Data : Clin J Gastroenterol. 2011 Aug ;4(4):185-97. Epub 2011 Jun 4. PMID: 26189518

Article Published Date : Jul 31, 2011

Study Type : Review

Additional Links

Substances : Caffeine, Capsaicin, Cinnamaldehyde, Curcumin, Diallyl sulfide, EGCG (Epigallocatechin gallate), Genistein, Lycopene, Resveratrol, Silymarin, Sulforaphane, Xanthohumol

Diseases : Liver Cancer

Pharmacological Actions : Chemopreventive

[+]

A systematic review of the efficacy of ergogenic aids for improving running performance.May 31, 2013

Click here to read the entire abstract

Pubmed Data : J Strength Cond Res. 2013 Jun ;27(6):1699-707. PMID: 22890496

Article Published Date : May 31, 2013

Study Type : Review

Additional Links

Substances : Caffeine, Sodium Bicarbonate

Diseases : Athletic Performance

Therapeutic Actions : Exercise, Exercise: Running

[+]

Alzheimer's disease, inflammation, and the role of antioxidants.Jun 15, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Alzheimers Dis Rep. 2020 Jun 16 ;4(1):175-183. Epub 2020 Jun 16. PMID: 32715278

Article Published Date : Jun 15, 2020

Study Type : Review

Additional Links

Substances : Caffeine, Turmeric, Vitamin E

Diseases : Alzheimer's Disease, Brain Inflammation

Pharmacological Actions : Neuroprotective Agents

[+]

An overview of natural plant products in the treatment of hepatocellular carcinoma.Jun 02, 2018

Click here to read the entire abstract

Pubmed Data : Anticancer Agents Med Chem. 2018 Jun 3. Epub 2018 Jun 3. PMID: 29866017

Article Published Date : Jun 02, 2018

Study Type : Review

Additional Links

Substances : Caffeine, Curcumin, Emodin, Lycopene, Phloretin, Quercetin, Resveratrol, Silibinin, Urolithin A

Diseases : Liver Cancer

Pharmacological Actions : Chemopreventive

[+]

Caffeine enhances the anti-tumor effect of 5-fluorouracil via increasing the production of reactive oxygen species in hepatocellular carcinoma.Oct 28, 2019

Click here to read the entire abstract

Pubmed Data : Med Oncol. 2019 Oct 29 ;36(12):97. Epub 2019 Oct 29. PMID: 31664534

Article Published Date : Oct 28, 2019

Study Type : In Vitro Study

Additional Links

Substances : Caffeine

Diseases : Liver Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil

[+]

Caffeine produced neuroprotective effect against Aβ neurotoxicity.Nov 30, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Adv Pharm Bull. 2017 Dec ;7(4):579-584. Epub 2017 Dec 31. PMID: 29399547

Article Published Date : Nov 30, 2017

Study Type : In Vitro Study

Additional Links

Substances : Caffeine

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Caffeine targets G6PDH to disrupt redox homeostasis and inhibit renal cell carcinoma proliferation.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Cell Dev Biol. 2020 ;8:556162. Epub 2020 Oct 6. PMID: 33123534

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Caffeine

Diseases : Kidney Cancer

Pharmacological Actions : Antiproliferative

[+]

Caffeine targets SIRT3 to enhance SOD2 activity in mitochondria. Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Cell Dev Biol. 2020 ;8:822. Epub 2020 Sep 1. PMID: 33015038

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Caffeine

Diseases : Ultraviolet Radiation Induced Damage

Pharmacological Actions : Antioxidants, Photoprotective

[+]

Coffee and caffine chronologically enhanced the antiamyloidogenic activity of melatonin through suppression of Aβ oligomerization.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Drug Des Devel Ther. 2015 ;9:241-72. Epub 2014 Dec 24. PMID: 25565776

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Caffeine, Coffee, Melatonin

Diseases : Alzheimer's Disease

Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation

Additional Keywords : Natural Substance Synergy

[+]

Coffee contains compounds which stimulate dopamine release.Oct 13, 2011

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2011 Oct 13. Epub 2011 Oct 13. PMID: 22019894

Article Published Date : Oct 13, 2011

Study Type : In Vitro Study

Additional Links

Substances : 5-hydroxytryptamides, Caffeine, Catechols, Chlorogenic Acid, Coffee, N-methylpyridinium, Pyrogallol, Trigonelline

Diseases : Dopamine Deficiency

Pharmacological Actions : Dopaminergic

[+]

Effect of caffeine, caffeic acid and their various combinations on enzymes of cholinergic, monoaminergic and purinergic systems critical to neurodegeneration in rat brain-In vitro.Sep 01, 2017

Click here to read the entire abstract

Pubmed Data : Neurotoxicology. 2017 Sep ;62:6-13. Epub 2017 Apr 29. PMID: 28465162

Article Published Date : Sep 01, 2017

Study Type : In Vitro Study

Additional Links

Substances : Caffeic Acid, Caffeine

Diseases : Neurodegenerative Diseases

Pharmacological Actions : Neuroprotective Agents, Regenerative

Additional Keywords : Nerve Regeneration

[+]

Green tea and caffeine have data to back up its fat metabolism-enhancing properties.Oct 01, 2011

Click here to read the entire abstract

Pubmed Data : Obes Rev. 2011 Oct ;12(10):841-51. PMID: 21951331

Article Published Date : Oct 01, 2011

Study Type : Commentary

Additional Links

Substances : B-complex, Caffeine, Carnitine, CLA (Conjugated Linoleic Acid), Fucoxanthin , Green Tea, Taurine, Tea

[+]

Green tea and caffeine improve endurance performance and enhance fat oxidation.Jan 01, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2016 ;62(3):141-61. PMID: 27465721

Article Published Date : Jan 01, 2016

Study Type : Review

Additional Links

Substances : Caffeine, Green Tea

Additional Keywords : Plant Extracts

[+]

Inhibition of biofilm formation of Pseudomonas aeruginosa by caffeine.Nov 26, 2019

Click here to read the entire abstract

Pubmed Data : Arch Microbiol. 2019 Nov 27. Epub 2019 Nov 27. PMID: 31773197

Article Published Date : Nov 26, 2019

Study Type : In Vitro Study

Additional Links

Substances : Caffeine

Diseases : Pseudomonas aeruginosa

Pharmacological Actions : Antimicrobial

Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation

[+]

L-theanine and caffeine have clear beneficial effects on sustained attention, memory, and suppression of distraction.Jan 04, 2017

Click here to read the entire abstract

Pubmed Data : Curr Pharm Des. 2017 Jan 5. Epub 2017 Jan 5. PMID: 28056735

Article Published Date : Jan 04, 2017

Study Type : Review

Additional Links

Substances : Caffeine, Theanine

Diseases : Cognitive Decline/Dysfunction, Memory Disorders

Pharmacological Actions : Neuroprotective Agents

[+]

Natural compounds attenuate heavy metal-induced PC12 cell damage. May 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Int Med Res. 2020 Jun ;48(6):300060520930847. PMID: 32552232

Article Published Date : May 31, 2020

Study Type : In Vitro Study

Additional Links

Substances : Caffeine, Gallic Acid, Resveratrol, Vitamin C, Vitamin E: alpha tocopherol

Diseases : Heavy Metal Toxicity, Neurodegenerative Diseases

Pharmacological Actions : Neuroprotective Agents

[+]

Plant-derived nootropics and human cognition: A systematic review.Jan 02, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Crit Rev Food Sci Nutr. 2022 Jan 3:1-25. Epub 2022 Jan 3. PMID: 34978226

Article Published Date : Jan 02, 2022

Study Type : Review

Additional Links

Substances : Ashwagandha, Bacopa, Caffeine, Ginkgo biloba

Diseases : Alzheimer's Disease, Anxiety, Dementia, Parkinson's Disease

Pharmacological Actions : Nootropic Agents

[+]

Studies also show that catechins may prevent the formation of amyloid-β plaques and enhance cognitive functions.May 29, 2017

Click here to read the entire abstract

Pubmed Data : J Alzheimers Dis. 2017 May 30. Epub 2017 May 30. PMID: 28582855

Article Published Date : May 29, 2017

Study Type : Review

Additional Links

Substances : Anthocyanins, Caffeine, Catechin , EGCG (Epigallocatechin gallate), Flavonoids, Gallic Acid, Polyphenols, Theophylline

Diseases : Alzheimer's Disease, Diabetic Complications

Pharmacological Actions : Antioxidants, Neuroprotective Agents

Additional Keywords : Alzheimer's disease, Anthocyanins, Antioxidants, caffeine, Catechin, Diabetic Complications, EGCG (Epigallocatechin gallate), Flavonoids, Gallic Acid, Neuroprotective Agents, POLYPHENOLS, Theophylline

[+]

The impact of phytochemicals in obesity-related metabolic diseases.Jan 29, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2023 Jan 30 ;15(3). Epub 2023 Jan 30. PMID: 36771408

Article Published Date : Jan 29, 2023

Study Type : Review

Additional Links

Substances : Caffeine, Coffee, Resveratrol, Sulforaphane

Diseases : Insulin Resistance, Metabolic Diseases, Obesity

Additional Keywords : Anti-Obesity Agents

[+]

The incidence of cataract blindness was found to be significantly lower in groups consuming higher amounts of coffee.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Ophthalmol. 2016 ;10:213-20. Epub 2016 Jan 27. PMID: 26869755

Article Published Date : Dec 31, 2015

Study Type : Review

Additional Links

Substances : Caffeine, Coffee

Diseases : Cataract

Additional Keywords : Dose Response, Risk Reduction

[+]

This review suggests that caffeine consumption, especially moderate quantities consumed through coffee or green tea.Nov 03, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Alzheimers Dis. 2020 Nov 4. Epub 2020 Nov 4. PMID: 33185612

Article Published Date : Nov 03, 2020

Study Type : Review

Additional Links

Substances : Caffeine

Diseases : Cognitive Decline/Dysfunction, Dementia

Pharmacological Actions : Neuroprotective Agents

[+]

Treatment of glaucoma with natural products and their mechanism of action: an update.Jan 25, 2022

Click here to read the entire abstract

Pubmed Data : Nutrients. 2022 Jan 26 ;14(3). Epub 2022 Jan 26. PMID: 35276895

Article Published Date : Jan 25, 2022

Study Type : Review

Additional Links

Substances : Anthocyanins, Baicalein, Barberry, Caffeine, Cannabis, Coenzyme Q10, Curcumin, Ginkgo biloba, Ginsenosides, Hesperidin, Resveratrol, Saffron, Tripterygium wilfordii, Vitamin B-3 (Niacin), Vitamin D

Diseases : Glaucoma

Pharmacological Actions : Antioxidants, Neuroprotective Agents

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View the Evidence: 89 Abstracts with Caffeine Research

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Acute caffeine supplementation is highly ergogenic for movement velocity in resistance exercise.Oct 22, 2019

Caffeine supplementation showed a significant ergogenic effect on muscle endurance and maximum strength in the bench press exercise.Jun 17, 2020

Coffee intake appears to exert a moderate protective effect against basal cell cancer development.Jul 06, 2016

Ergogenic effects of acute caffeine intake on muscular endurance and muscular strength in women.May 26, 2021

Pre-exercise intake of a moderate dose of caffeine may effectively increase fat utilization during aerobic exercise.Nov 23, 2020

A combination of 500-mg G-hesperidin and 75-mg caffeine for 12 weeks significantly reduced abdominal fat.Dec 31, 2015

Blood dopamine level enhanced by caffeine in men after treadmill running.Oct 31, 2019

Caffeinated chewing gum increases repeated sprint performance and augments increases in testosterone in competitive cyclists.Dec 01, 2010

Caffeinated chewing gums and gels may enhance resistance exercise performance even when consumed 10 min before exercise.Jul 21, 2021

Caffeine compares favorably to amphetamine in reducing the symptoms of treatment-resistant obsessive-compulsive disorder.Nov 01, 2009

Caffeine consumption appears to be associated with higher levels of physical activity in Japanese women.Feb 05, 2018

Caffeine exerted a positive effect on time to exhaustion at MLSS workload that was accompanied by shifts in substrate utilization during exercise.Dec 31, 2014

Caffeine given at breakfast significantly stimulated ketone production in a dose-dependent manner.Nov 24, 2016

Caffeine improves muscular endurance and aerobic performance in adolescent athletes.Jun 14, 2020

Caffeine in coffee can prevent and help brain function in Alzheimer's DiseaseSep 01, 2009

Caffeine increases the secretion of cortisol. Sep 01, 2005

Caffeine ingestion attenuates fatigue-induced loss of muscle torque complexity.Oct 02, 2017

Caffeine intake was related to moderately better cognitive maintenance over 5 years in older women with vascular disorders.Dec 31, 2012

Caffeine is as effective as aminophylline, while it is superior to aminophylline regarding its overall safety.Dec 31, 2017

Caffeine may play a protective role in T2DM via increased beta cell function.Jun 14, 2020

Caffeine optimizes HIIT benefits on obesity-associated metabolic adversity in women.Jul 31, 2020

Caffeine potentiates chemotherapy for metastatic osteosarcoma.Sep 01, 2009

Caffeine results in explicit memory enhancement for young adults during the early morning.Dec 31, 2015

Coffee and caffeine may be associated with improved capacity to efficiently repair DNA damage.Dec 31, 2014

consumption of caffeinated coffee was inversely associated with melanoma risk among men.Feb 19, 2017

Daily caffeine intake reduces insulin sensitivity. Dec 01, 2007

Implementing a caffeine-EGCG-containing drink prior to exercise may improve muscle mass, fitness, and lipid profiles in overweight women.Oct 01, 2010

Increasing caffeine intake and caffeinated coffee consumption is associated with decreased risk of cutaneous malignant melanomas.Jul 09, 2015

Ingesting matcha with caffeine improves both attention and work performance when suffering from psychological stress.May 16, 2021

Low dose of caffeine enhances the efficacy of antidepressants in major depressive disorder.Jan 04, 2017

Moderate coffee intake was associated with smaller invasive primary tumors and lower proportions of ER positive tumors compared with patients with low consumption.Feb 16, 2015

Tea catechin and caffeine activate brown adipose tissue and increase cold-induced thermogenic capacity in humans.Mar 31, 2017

Tryptophan, Niacin, Calcium, and Caffeine may have therapeutic value in the treatment of migraines. Jan 01, 2001

Vitamin A (retinol), caffeine and ruscogenine have anti-cellulite properties.Jul 01, 2001

Caffeine might improve outcomes in pertussis by preventing apnoea and decreasing pulmonary complications.Mar 27, 2018

A combination of caffeine, arginine, soy isoflavones, and L-carnitine enhances both lipolysis and fatty acid oxidation in animal model of obesity. Oct 01, 2007

Advancing combination treatment with cilostazol and caffeine for Alzheimer's disease in high fat-high fructose-STZ induced model of amnesia.Mar 09, 2022

Alpha-tocopherol treatment is able to inhibit oxidative stress and anxiety-like behaviour evoked by caffeine.Dec 31, 2018

Caffeine actually protected mice from genotoxicity and mutagenicity attributed to aging.May 18, 2017

Caffeine and antioxidants have the ability to reverse cadmium-induced testicular injury.Dec 27, 2020

Caffeine and EGCG alleviate high-trans fatty acid and high-carbohydrate diet-induced NASH.Dec 31, 2020

Caffeine and lycopene provided protective effects against experimentally induced diabetes mellitus.Sep 23, 2015

Caffeine demonstrates anti-influenza activity. May 01, 2003

Caffeine exhibits radioprotective properties in whole-body irradiated male mice.Mar 01, 2003

Caffeine may abrogate lipopolysaccharide-induced oxidative stress and neuroinflammation.Nov 07, 2019

Caffeine plus haloperidol reduces fatigue in an experimental model of Parkinson's disease.Mar 14, 2023

Caffeine prevents neurodegeneration and behavioral alterations in a mice model of agitated depression.Nov 08, 2019

Caffeine prevents UV-B induced cataract formation in mice. Jul 03, 2009

Caffeine promotes conversion of palmitic acid to palmitoleic acid.Dec 31, 2017

Caffeine protects against stress-induced murine depression.Jan 30, 2021

Caffeine provides a significant neuroprotection against aluminum chloride induced neurotoxicity.Mar 06, 2018

Caffeine, vanillin, and their combination could potentially be an effective regimen in managing AlCl3-induced renal toxicity.Dec 31, 2022

Chronic caffeine consumption has a potentially good protective effect against Alzheimer's disease.Dec 31, 2014

Coadministration of epigallocatechin-3-gallate and caffeine in low dose ameliorates obesity and nonalcoholic fatty liver disease in obese rats.Feb 10, 2019

Crude caffeine reduces memory impairment and amyloidβ(1-42) levels in an Alzheimer's mouse model.Nov 30, 2012

Effects of epigallocatechin gallate, caffeine, and their combination on fat accumulation in high-glucose diet-fed Caenorhabditis elegans.Jul 23, 2023

Effects of photobiomodulation and caffeine treatment on acute kidney injury in a hypoxic ischemic neonatal rat model.Jul 31, 2023

Long-term caffeine consumption reverses tumor-induced suppression of the innate immune response in adult mice. Dec 01, 2008

Low doses of caffeine exert a hepatoprotective effect against carbon tetrachloride induced liver damage in rats.Aug 01, 2016

Phenobarbital-induced adverse effects could be reduced by a co-treatment with caffeine.Jun 21, 2017

Pyrocatechol acts as an antioxidant together with caffeine to prevent cataract formation.Jan 26, 2017

Remedial effects of caffeine against depressive-like behaviour in mice by modulation of neuroinflammation and BDNF.Apr 04, 2021

Topica sulfo-carrabiose and caffeine have anti-cellulite properties.Aug 30, 2010

Topical caffeine appears to contribute to reducing cellulite.Mar 01, 2008

Topical caffeine may have a therapeutic role in cellulite reduction.Sep 01, 2008

White Tea, Green Tea, EGCG (Epigallocatechin gallate), and Caffeine inhibit colon cancer progression. Jan 01, 2007

A comprehensive review of complementary and alternative treatments for alopecia. Jan 31, 2019

A review of in vitro and vivo antihepatocarcinogenic effects of natural compounds. Jul 31, 2011

A systematic review of the efficacy of ergogenic aids for improving running performance.May 31, 2013

Alzheimer's disease, inflammation, and the role of antioxidants.Jun 15, 2020

An overview of natural plant products in the treatment of hepatocellular carcinoma.Jun 02, 2018

Caffeine enhances the anti-tumor effect of 5-fluorouracil via increasing the production of reactive oxygen species in hepatocellular carcinoma.Oct 28, 2019

Caffeine

View the Evidence:
89 Abstracts with Caffeine Research