Cannabis

Name	AC	CK
Multiple Sclerosis	53	466
Epilepsy	46	225
Neuropathic Pain	24	205
Inflammation	61	155
Tourette Syndrome	8	131
Anxiety	25	111
Inflammatory Bowel Diseases	16	107
Pain	10	107
Parkinson's Disease	24	85
Autism Spectrum Disorders	9	83
Chronic Pain	19	81
Cancers: All	46	79
Epilepsy: Childhood	6	76
Dravet syndrome	8	64
Huntington Disease	10	55
Fibromyalgia	6	54
HIV Infections	9	53
Insomnia	5	53
Morphine Tolerance/Dependence	7	52
Alzheimer's Disease	27	50
Glioma	23	50
Stroke: Attenuation/Recovery	6	49
Seizures	9	47
Obsessive-Compulsive Disorder	4	45
Spinal Cord Injuries	5	45
Neurodegenerative Diseases	27	44
Breast Cancer	24	43
Stroke	4	43
Oxidative Stress	21	41
Sleep Disorders	6	41
Anxiety Disorders	9	40
Brachial Plexus Neuropathies	2	40
Glioblastoma Multiforme	12	40
Opioid Tolerance/Dependence	1	40
Brain Inflammation	24	37
Bladder Dysfunction	3	34
Depression	16	34
Memory Disorders	6	34
Muscle Spasticity	3	34
Lipopolysaccharide-Induced Toxicity	16	33
Dementia	7	32
Diabetes Mellitus: Type 2	7	32
Marijuana Addiction/Withdrawal	3	32
Attention Deficit Hyperactivity Disorder	2	30
Cancer: Pain	6	30
Nonalcoholic fatty liver disease (NAFLD)	4	30
Overactive Bladder	1	30
Schizophrenia	15	29
Stroke: Ischemic	4	29
Acne	4	26
Diabetic Neuropathies	3	26
Lung Cancer	13	26
Post-Traumatic Stress Disorders (PTSD)	10	26
Amyotrophic lateral sclerosis (ALS)	4	25
Cancer Metastasis	11	25
Hyperalgesia	8	25
Lennox-Gastaut Syndrome	6	25
Colitis	8	24
Obesity	8	24
Psychoses	6	24
Glaucoma	5	22
Head and Neck Cancer	3	22
Allodynia	7	21
Lymphoma	5	21
Amyotrophic Lateral Sclerosis	9	20
Diabetes	1	20
Glioblastoma	11	20
Headache: Migraine	2	20
Hypertension	4	20
Hypoglycemia	1	20
Impairment: Driving Related	1	20
Incontinence	1	20
Peripheral Nerve Diseases	1	20
Social Anxiety Disorder (SAD)	1	20
Vaccine-induced Toxicity	1	20
Brain Cancer	4	19
Colon Cancer	9	17
Brain: Microglial Activation	6	16
Breast Cancer: Triple Negative	9	16
Brain Ischemia	7	15
Constipation	3	15
Ulcerative Colitis	2	15
Astrocytoma	4	14
Brain Injury: Traumatic	3	14
Chemotherapy-Induced Toxicity: Cisplatin	5	14
Lipid Peroxidation	2	14
Metabolic Syndrome X	2	14
Prostate Cancer	11	14
Atherosclerosis	3	13
Brain Damage: Hypoxic Ischemic Insult	6	13
Encephalopathy	2	13
Rheumatoid Arthritis	4	13
Cerebral Ischemia	5	12
Cognitive Decline/Dysfunction	6	12
Colorectal Cancer	8	12
Epileptic Seizures	2	12
Hepatitis C	3	12
Insulin Resistance	2	12
Melanoma	7	12
Metabolic Diseases	2	12
Skin Cancer	5	12
Cardiovascular Diseases	5	11
Cirrhosis	2	11
Clostridium Infections	2	11
Diabetic Complications	6	11
Endocannabinoid Disorders	2	11
Nausea: Chemotherapy-Induced	2	11
Opiate Addiction/Withdrawal	2	11
Ovarian Cancer	2	11
Psychiatric Disorders	9	11
Anorexia: Dementia-Associated	1	10
Bronchial Asthma	1	10
C-Reactive Protein (CRP)	1	10
Chemotherapy	1	10
Chemotherapy-Induced Toxicity	1	10
Child Behavior Disorders	1	10
Cocaine Addiction	1	10
Crack Addiction/Withdrawal	1	10
Delirium: Drug-Induced	1	10
Dry Skin	1	10
Heroin Addication/Withdrawal	1	10
Learning disorders	1	10
Lymphoma: Mantle Cell	1	10
Multiple Sclerosis: Relapsing-Remitting	1	10
Myocardial Infarction	3	10
Myocardial Ischemia	3	10
Nausea: Pregnancy-Associated	1	10
Neurogenic Bladder	1	10
Neuropathic Pain: HIV-associated	1	10
Neuropathy: HIV associated	1	10
Organ Transplantation: Kidney	1	10
Overweight	1	10
Pancreatitis: Chronic	1	10
Phantom Limb	1	10
Quality of Life: Poor	1	10
Rheumatic Diseases	1	10
Seborrheic Dermatitis	1	10
Stress	1	10
Sturge-Weber Syndrome	1	10
Temporal Lobe Epilepsy (TLE)	1	10
Tuberous Sclerosis	1	10
Arthritis	4	9
Autoimmune Diseases	6	9
Endocannabinoid System	7	9
Alcohol Toxicity	4	8
Colon Cancer: Prevention	2	8
Endotoxemia	2	8
Middle Cerebral Artery Occlusion (MCAO)	4	8
Pancreatic Cancer	7	8
Traumatic Memory Formation	4	8
Brain: Oxidative Stress	3	7
Coronavirus Infection	6	7
Gastrointestinal Inflammation	2	7
Liver Cancer	4	7
Aging: Brain	3	6
Astrocytoma: Grade IV	1	6
Attention Deficit Disorder with Hyperactivity	1	6
Chemotherapy-Induced Toxicity: Doxorubicin	4	6
Diabetes Mellitus: Type 1	3	6
Diabetes Mellitus: Type 1: Prevention	3	6
Diabetes: Cataract	2	6
Emesis	1	6
Epidermolysis Bullosa	1	6
Fatigue	2	6
Hypersensitivity	2	6
Neuroblastoma	3	6
Osteoarthritis	5	6
Staphylococcus aureus infection	5	6
Vomiting	1	6
Acute Myeloid Leukemia	2	5
Alcoholic Liver Disease	1	5
Asthma	3	5
Cachexia	3	5
Chemotherapy and Radiation Toxicity	2	5
Chemotherapy-Induced Nausea	3	5
Chemotherapy-Induced Toxicity: Paclitaxel	2	5
Cholangiocarcinoma	1	5
Drug Abuse	3	5
Encephalomyelitis	3	5
Gliomas	3	5
Leukemia	4	5
Liver Fibrosis	2	5
Psoriasis	4	5
Psychiatric Disorder: Conditioned Fear	3	5
Psychotic Disorders	4	5
Staphylococcus aureus: Methicillin-resistant (MRSA)	3	5
Thyroid Cancer	3	5
Tremor	2	5
AIDS	2	4
Acute Respiratory Distress Syndrome	2	4
Allergic Airway Diseases	2	4
Appetite Disorders: Loss/Lack of	1	4
Arteriosclerosis	1	4
Bladder Cancer	3	4
Brain Damage	3	4
Breast Cancer: Lung Metastasis	1	4
Breast Cancer: Prevention	1	4
Cachexia: Cancer	3	4
Cardiac Arrhythmias	1	4
Cervical Cancer	2	4
Chemotherapy-Induced Toxicity: Oxaliplatin	1	4
Chemotherapy-Induced Toxicity: Vincristine	1	4
Cocaine Toxicity	2	4
Dermatitis	1	4
Endothelial Dysfunction	2	4
Eye Damage	1	4
Febrile Seizures	2	4
Fulminant Hepatic Failure	1	4
Headache	2	4
Hepatic Encephalopathy	1	4
High Cholesterol	2	4
High Fat Diet	2	4
Hydrogen Peroxide Induced Toxicity	4	4
Immune Disorders: Low Immune Function	1	4
Iron Overload	2	4
Ischemia	2	4
Liver Failure: Acute	1	4
Low Immune Function: Splenic Dysfunction	1	4
Rhabdomyosarcoma	1	4
Sepsis	1	4
Uveitis	1	4
Acute T cell Leukemias	2	3
Acute lymphoblastic leukemia (ALL)	2	3
Aging	2	3
Atopic Dermatitis	2	3
Autism	2	3
Bipolar Disorder	1	3
Breast Cancer: Metastatic	2	3
Central Nervous System Diseases	2	3
Cough	1	3
Drug Addiction	2	3
Endometrial Cancer	1	3
Epilepsy: Infant	1	3
Epilepsy: Malignant Migrating Partial Seizures	1	3
Escherichia coli Infections	3	3
Fibrosis	2	3
Gastric Cancer	3	3
Gastrointestinal Diseases	2	3
Gram-Positive Bacterial Infections	3	3
Immune Disorders	2	3
Multiple Myeloma	2	3
Neuralgia	1	3
Neurologic Disorders	2	3
Oral Mucositis	2	3
Trigeminal Neuralgia	2	3
Alcohol Addiction	2	2
Alcohol Withdrawal	1	2
Amphetamine Addiction/Withdrawal	1	2
Angelman Syndrome	1	2
Animal Diseases: Simian Immunodeficiency Virus (SIV)	1	2
Ascites	1	2
Bone Fractures	1	2
Brain Edema	1	2
Cachexia: Chemotherapy Induced	1	2
Cancers: Drug Resistant	2	2
Candida Albicans	2	2
Candida Infection	1	2
Carcinoma: Non-Small-Cell Lung	1	2
Cardiomyopathy	1	2
Cerebral Hypoperfusion	1	2
Chemotherapy-Induced Toxicity: Cyclophosphamide	1	2
Chemotherapy-Induced Toxicity: 5-fluorouracil	1	2
Cocaine Withdrawal	1	2
Degenerative Disk Disease	1	2
Depression	1	2
Depressive Disorder	1	2
Dermatitis: Contact	1	2
Diabetes: Cardiovascular Illness	1	2
Diabetes: Memory Problems	1	2
Diabetes: Oxidative Stress	1	2
Diabetic Neuropathy	1	2
Diabetic Retinopathy	1	2
Drug-Induced Toxicity: Epilepsy Drugs	1	2
Epilepsy: Drug-Induced	1	2
Fatigue: Excercise-Induced	1	2
Fatty Liver	1	2
Friedreich Ataxia	1	2
Gastroschisis	1	2
Gram-Negative Bacterial Infections	2	2
Heart Attack	1	2
Hypercholesterolemia	1	2
Hypersensitivity: Type IV	1	2
Hypertension: Pulmonary	1	2
Hypothermia	1	2
Immune Dysregulation: TH1/TH2 imbalance	1	2
Infant Neurological Development	1	2
Inflammation: Neutrophil-Mediated	1	2
Interstitial Lung Diseases	1	2
Irritable Bowel Syndrome	2	2
Leishmaniasis	1	2
Listeria Infections	1	2
Liver Damage	1	2
Liver Disease	1	2
Liver Injury: Ischemia/reperfusion	1	2
Lung Inflammation	1	2
Malaria	1	2
Memory Disorders: Drug-Induced	1	2
Menopausal Syndrome	1	2
Mitochondrial Dysfunction	1	2
Mood Disorders	1	2
Muscle Soreness	1	2
Myocarditis: Autoimmune	1	2
Neonatal Stroke	1	2
Neurological Conditions	2	2
Oral Cancer	1	2
Osteoporosis	2	2
Periodontitis	1	2
Peripheral Neuropathies	1	2
Phencyclidine (PCP) Induced Toxicity	1	2
Prenatal Chemical Exposures	1	2
Prion Diseases	1	2
Pseudomonas aeruginosa	1	2
Rett Syndrome	1	2
Sciatic Nerve Crush Injury	1	2
Skin Diseases: Inflammatory	1	2
Spinal Cord Inflammation	1	2
Tardive Dyskinesia	1	2
Traumatic Brain Injury	1	2
Tumors	2	2
Ultraviolet Radiation Induced Damage	2	2
Urinary Bladder Diseases	1	2
Wound Healing	1	2
Acetaminophen (Tylenol) Toxicity	1	1
Acinetobacter baumannii infection	1	1
Acquired Immunodeficiency Syndrome	1	1
Allergies	1	1
Anorexia	1	1
Appetite Disorders	1	1
Arrhythmias: Cardiac	1	1
Arthritis: Rheumatoid	1	1
Auditory Diseases	1	1
Bone Diseases	1	1
Bronchial Diseases	1	1
Burkitt Lymphoma	1	1
Cadmium Poisoning	1	1
Cancers: Multi-Drug Resistant	1	1
Cardiovascular Disease: Prevention	1	1
Diabetes: Cognitive Dysfunction	1	1
Dry Eye Syndromes	1	1
Dystonia	1	1
Ebola Virus Infections	1	1
Eczema	1	1
Epstein-Barr Virus Infections	1	1
Eye Diseases	1	1
Gynecomastia	1	1
Hepatitis	1	1
Hepatitis: Autoimmune	1	1
Herpes Simplex Virus Type 2	1	1
Herpes family viruses	1	1
Herpes: Kaposi-Associated	1	1
Hypotension	1	1
Influenza	1	1
Intestinal Permeability	1	1
Joint Diseases	1	1
Kaposi Disease	1	1
Kaposi's Sarcoma	1	1
Kidney Cancer	1	1
Kidney Damage	1	1
Leukemia: T-cell acute Lymphoblastic	1	1
Lung Injury: Acute	1	1
Methicillin-resistant Staphylococcus aureus	1	1
Migraine Disorders	1	1
Movement Disorders	1	1
Oncovirus	1	1
Prostate: PSA Doubling	1	1
Pruritus	1	1
Skin Diseases	1	1
Testicular Cancer	1	1
Thymoma	1	1
Tobacco Addiction/Withdrawal	1	1

Name	AC	CK
Neuroprotective Agents	151	447
Anti-Inflammatory Agents	148	429
Analgesics	61	408
Anticonvulsants	54	308
Apoptotic	92	172
Antiproliferative	78	167
Anti-Anxiety Agents	33	136
Antioxidants	52	101
Immunomodulatory	30	87
Tumor Necrosis Factor (TNF) Alpha Inhibitor	30	74
Antidepressive Agents	20	70
Anti-metastatic	28	61
Angiogenesis Inhibitors	15	47
Cyclooxygenase 2 Inhibitors	11	47
Antineoplastic Agents	27	46
Antinoceceptive	12	45
Chemopreventive	9	35
Chemotherapeutic	22	31
Vasodilator Agents	5	31
Anti-Apoptotic	13	24
Antispasmodic	2	24
Autophagy Up-regulation	10	24
Hypoglycemic Agents	3	24
Antihypertensive Agents	6	23
Cardioprotective	11	23
Immunosuppressive Agents	8	23
Interleukin-6 Downregulation	13	23
NF-kappaB Inhibitor	13	23
Hepatoprotective	9	22
Matrix metalloproteinase-9 (MMP-9) inhibitor	2	22
Vascular Endothelial Growth Factor Inhibitors	3	22
Anxiolytic	2	21
Interleukin-1 beta downregulation	11	20
Chemoprotective Agents	7	19
Enzyme Inhibitors	5	19
Cell cycle arrest	11	18
Anti-Tumor	9	17
Neurogenesis	8	15
Anti-Bacterial Agents	11	14
Superoxide Dismutase Up-regulation	5	14
Anticarcinogenic Agents	7	13
Hypolipidemic	5	13
Interferon Gamma Reducer	6	13
Antipsychotic Agents	8	12
Chemosensitizer	8	12
MicroRNA modulator	6	12
Gastrointestinal Agents	7	11
Antiemetics	1	10
Brain-derived neurotrophic factor modulator	5	10
Bronchodilator Agents	1	10
GABA Modulators	1	10
Nitric Oxide Inhibitor	3	10
Immunomodulatory: Th17 downregulation	4	9
Interleukin-10 upregulation	5	9
Appetite Stimulants	3	8
Prostaglandin PGE2 downregulation	2	8
Anti-Angiogenic	6	7
Antiviral Agents	6	7
Cannabinoid Receptor Antagonist/Inverse Agonist	3	7
Cytotoxic	3	7
Nrf2 activation	5	7
P38 Mitogen-Activated Protein Kinase Modulator	2	7
Anti-Fibrotic	3	6
Catalase Up-Regulation	2	6
Interleukin-10 downregulation	2	6
Interleukin-17 downregulation	4	6
Radiosensitizer	3	6
Vascular Cell Adhesion Molecule-1 Inhibitor	2	6
Interleukin-8 downregulation	4	5
Neuritogenic	3	5
Anti-atherogenic	1	4
Anticholesteremic Agents	2	4
Antifungal Agents	3	4
Caspase-3 Activation	3	4
Gastroprotective	2	4
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor	1	4
Interleukin-4 downregulation	2	4
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	4
Matrix metalloproteinase-2 (MMP-2) inhibitor	2	4
Osteoprotective	3	4
Vascular Endothelial Growth Factor A Inhibitor	2	4
Vascular Endothelial Growth Factor Regulator	2	4
Acetylcholinesterase Inhibitor	2	3
Aldose reductase inhibitor	1	3
Antimicrobial	2	3
Laxative	1	3
Prophylactic Agents	2	3
Renoprotective	2	3
Sedative effects	1	3
Vanilloid Receptor-1 Modulator	1	3
Anti-Androgen	1	2
Anti-Infective Agents	1	2
Anti-Platelet	1	2
Calcium Channel Blockers	1	2
Cyclooxygenase Inhibitors	1	2
Enzyme Activators	1	2
Epidermal growth factor receptor (EGFR) inhibitor	1	2
Glycine Agents	1	2
Heme oxygenase-1 inducer	1	2
Heme oxygenase-1 up-regulation	1	2
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	2	2
Immunomodulatory: T-Cell down-regulation	1	2
Immunostimulatory	1	2
Interleukin-12 downregulation	1	2
Interleukin-2 Downregulation	1	2
Interleukin-5 downregulation	1	2
Intracellular adhesion molecule-1 (ICAM-1)	1	2
Malondialdehyde Down-regulation	1	2
Neuroplasticity enhancement	1	2
Pancreato Protective Agents	1	2
Photoprotective	2	2
Platelet Aggregation Inhibitors	1	2
Redox Modulator	1	2
Regenerative	1	2
STAT3 Inhibitor	1	2
Topoisomerase II Inhibitor	2	2
interleukin-13 down-regulation	1	2
5-Lipoxygenase Inhibitor	1	1
Angiotensin-Converting Enzyme Inhibitors	1	1
Anti-Allergic Agents	1	1
Anti-Cachexic Agents	1	1
Anti-Proliferative	1	1
Anti-Psychotic	1	1
Antimutagenic Agents	1	1
Caspase-8 activation	1	1
Caspase-9 Activation	1	1
Cyclooxygenase 1 Inhibitor	1	1
Interleukin-2 upregulation	1	1
Interleukin-4 upregulation	1	1
Interleukin-6 upregulation	1	1
NADPH Oxidase Inhibitors	1	1
Neuroimmunomodulation	1	1
Paraptosis	1	1
Phase II Detoxification Enzyme Inducer	1	1
Transient receptor potential vanilloid type-2 activation	1	1
Tumor Suppressor Protein p53 Upregulation	1	1
Wnt/β-catenin signaling pathway modulation	1	1
apoptosis	1	1

[+]

A review and meta-analysis of the efficacy and safety of cannabidiol in epilepsy.Nov 02, 2018

Click here to read the entire abstract

Pubmed Data : Drugs. 2018 Nov 3. Epub 2018 Nov 3. PMID: 30390221

Click here to read the entire abstract

Pubmed Data : Arch Pediatr Adolesc Med. 2009 Jul;163(7):601-7. PMID: 21426373

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2017 ;8:81. Epub 2017 Feb 24. PMID: 28286481

Article Published Date : Dec 31, 2016

Study Type : Meta Analysis, Review

Additional Links

Substances : Cannabidiol

Diseases : Stroke

Pharmacological Actions : Vasodilator Agents

[+]

[+]

Cannabidiol could be useful in Dravet syndrome treatments. Mar 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pharmacol Res Perspect. 2016 Apr ;4(2):e00220. Epub 2016 Mar 5. PMID: 27069631

Article Published Date : Mar 31, 2016

Study Type : Human Study

Additional Links

Substances : Cannabidiol

Diseases : Dravet syndrome, Endocannabinoid Disorders

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Endocannabinoid System

[+]

Cannabidiol could reduce severe behavioural problems in children and adolescents with intellectual disability. May 31, 2020

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Pubmed Data : Br J Clin Pharmacol. 2020 Jun 1. Epub 2020 Jun 1. PMID: 32478863

Article Published Date : May 31, 2020

Study Type : Human Study

Additional Links

Substances : Cannabidiol

Diseases : Child Behavior Disorders, Learning disorders

Pharmacological Actions : Neuroprotective Agents

[+]

Cannabidiol for rapid eye movement sleep behavior disorder. Mar 21, 2021

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Pubmed Data : Mov Disord. 2021 Mar 22. Epub 2021 Mar 22. PMID: 33754375

Article Published Date : Mar 21, 2021

Study Type : Human Study

Additional Links

Substances : Cannabidiol

Diseases : Parkinson's Disease

[+]

[+]

Cannabidiol in the treatment of post-traumatic stress disorder.Dec 12, 2018

Click here to read the entire abstract

Pubmed Data : J Altern Complement Med. 2018 Dec 13. Epub 2018 Dec 13. PMID: 30543451

Article Published Date : Dec 12, 2018

Study Type : Human Study

Additional Links

Substances : Cannabidiol

Diseases : Post-Traumatic Stress Disorders (PTSD)

Additional Keywords : Significant Treatment Outcome

[+]

Click here to read the entire abstract

Pubmed Data : Curr Opin Support Palliat Care. 2020 Jun ;14(2):87-93. PMID: 32332209

Click here to read the entire abstract

Pubmed Data : Br J Clin Pharmacol. 2010 Nov;70(5):656-63. PMID: 21039759

Article Published Date : Nov 01, 2010

Study Type : Human Study

Additional Links

Substances : Cannabis

Diseases : Chemotherapy, Chemotherapy-Induced Toxicity, Nausea: Chemotherapy-Induced

Pharmacological Actions : Antiemetics

[+]

Cannabis extracts can be a useful and safe option for patients with MS with moderate to severe spasticity resistant to common antispastic drugs.May 08, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Clin Infect Dis. 2020 Apr 16. Epub 2020 Apr 16. PMID: 32296832

Click here to read the entire abstract

Pubmed Data : Pak J Pharm Sci. 2015 Jul ;28(4):1389-95. PMID: 26142529

Article Published Date : Jun 30, 2015

Study Type : Human Study

Additional Links

Substances : Cannabis

Diseases : Acne, Seborrheic Dermatitis

Additional Keywords : Cannabis Seed

[+]

Cannabis significantly reduces the use of prescription opioids and improves quality of life.Dec 26, 2020

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Pubmed Data : Pain Med. 2020 Dec 27. Epub 2020 Dec 27. PMID: 33367882

Click here to read the entire abstract

Pubmed Data : Isr Med Assoc J. 2011 Aug ;13(8):455-8. PMID: 21910367

Article Published Date : Aug 01, 2011

Study Type : Human Study

Additional Links

Substances : Cannabis

Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Drug Sparing

[+]

Cannabis users report greater pain relief in combination with opioids than when opioids are used alone.Jan 31, 2015

Click here to read the entire abstract

Pubmed Data : Drug Alcohol Depend. 2015 Feb 1 ;147:144-50. Epub 2014 Dec 10. PMID: 25533893

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Rheumatology (Oxford). 2006 Jan ;45(1):50-2. Epub 2005 Nov 9. PMID: 16282192

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Isr Med Assoc J. 2017 Feb ;19(2):79-84. PMID: 28457055

Article Published Date : Jan 31, 2017

Study Type : Human Study

Additional Links

Substances : Cannabidiol, Hemp Seed

Diseases : Vaccine-induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antinoceceptive , Neuroprotective Agents

Additional Keywords : Plant Extracts

Anti Therapeutic Actions : Vaccination: HPV (Gardasil)

[+]

CBD has anxiolytic properties in human volunteers submitted to a stressful situation.Dec 31, 1992

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Pubmed Data : J Psychopharmacol. 1993 Jan ;7(1 Suppl):82-8. PMID: 22290374

Click here to read the entire abstract

Pubmed Data : Epilepsy Behav. 2018 Mar 8. Epub 2018 Mar 8. PMID: 29526578

Article Published Date : Mar 07, 2018

Study Type : Human Study

Additional Links

Substances : Cannabidiol

Diseases : Epilepsy

Pharmacological Actions : Anticonvulsants

[+]

CBD-rich botanical extract may be beneficial for symptomatic treatment of ulcerative colitis.Mar 09, 2018

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Pubmed Data : Inflamm Bowel Dis. 2018 Mar 10. Epub 2018 Mar 10. PMID: 29538683

Article Published Date : Mar 09, 2018

Study Type : Human Study

Additional Links

Substances : Cannabidiol

Diseases : Ulcerative Colitis

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Delta9-tetrahydrocannabinol administration led to the inhibition of the VEGF Pathway in Two Patients with Glioblastoma Multiforme.Aug 14, 2004

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Psychopharmacology (Berl). 2021 Apr 4. Epub 2021 Apr 4. PMID: 33813611

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Complement Ther Med. 2013 Oct ;21(5):473-80. Epub 2013 Jul 25. PMID: 24050582

Article Published Date : Sep 30, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Gastroenterol Hepatol. 2013 Oct ;11(10):1276-1280.e1. Epub 2013 May 4. PMID: 23648372

Additional Keywords : Risk Reduction, Significant Treatment Outcome

[+]

Online discussions indicate that cannabis is considered therapeutic for ADHD.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Neurol. 2016 May 9. Epub 2016 May 9. PMID: 27159993

Article Published Date : May 08, 2016

Study Type : Human Study

Additional Links

Substances : Cannabidiol, Cannabis, Delta-tetrahydrocannabinol (THC)

Diseases : Huntington Disease

Additional Keywords : Plant Extracts, Safety of Natural Substances

[+]

Sativex successfully treats neuropathic pain characterised by allodynia.Dec 14, 2007

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Pubmed Data : Pain. 2007 Dec 15 ;133(1-3):210-20. Epub 2007 Nov 7. PMID: 17997224

Article Published Date : Dec 14, 2007

Click here to read the entire abstract

Pubmed Data : Clin Ther. 2007 Sep ;29(9):2068-79. PMID: 18035205

Article Published Date : Aug 31, 2007

Study Type : Human Study

Additional Links

Substances : Cannabidiol, Cannabis, Delta-tetrahydrocannabinol (THC)

Diseases : Multiple Sclerosis, Neuropathic Pain

Pharmacological Actions : Analgesics

Additional Keywords : Plant Extracts

[+]

THC appears therapeutic for anorexia and disturbed behavior in patients with Alzheimer's disease.Aug 31, 1997

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Pubmed Data : Int J Geriatr Psychiatry. 1997 Sep ;12(9):913-9. PMID: 9309469

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Pubmed Data : Int Clin Psychopharmacol. 2016 Mar 21. Epub 2016 Mar 21. PMID: 27003093

Article Published Date : Mar 20, 2016

Study Type : Human Study

Additional Links

Substances : Cannabidiol, Cannabis, Delta-tetrahydrocannabinol (THC)

Diseases : Multiple Sclerosis

[+]

The present study suggests that THC does not selectively affect limbic regions, but rather interferes with sensory processing.Oct 29, 2015

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Pubmed Data : Neuropsychopharmacology. 2015 Oct 30. Epub 2015 Oct 30. PMID: 26514581

Article Published Date : Oct 29, 2015

Study Type : Human Study

Additional Links

Substances : Delta-tetrahydrocannabinol (THC)

Diseases : Chronic Pain

Pharmacological Actions : Analgesics

[+]

These findings suggest that CBD has beneficial effects in patients with schizophrenia.Dec 14, 2017

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Pubmed Data : Am J Psychiatry. 2017 Dec 15:appiajp201717030325. Epub 2017 Dec 15. PMID: 29241357

Article Published Date : Dec 14, 2017

Study Type : Human Study

Additional Links

Substances : Cannabidiol

Diseases : Schizophrenia

[+]

These findings support efficacy of artisanal CBD preparations in seizure reduction with few significant side effects.Feb 07, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Mol Neurosci. 2017 ;10:14. Epub 2017 Jan 24. PMID: 28174520

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Substances : Cannabinoids

Diseases : Inflammation, Pancreatitis: Chronic

Pharmacological Actions : Anti-Inflammatory Agents, Immunosuppressive Agents

Additional Keywords : Anti-Inflammatory Agents, Cannabinoids, Immunosuppressive Agents, Inflammation, Pancreatitis: Chronic

[+]

These results suggest that CBD has anxiolytic properties.Jan 31, 2004

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Pubmed Data : Epilepsy Res. 2021 Mar 8 ;172:106603. Epub 2021 Mar 8. PMID: 33725662

Article Published Date : Mar 07, 2021

Study Type : Human Study

Additional Links

Substances : Cannabidiol

Diseases : Epilepsy

[+]

Whole-plant cannabis extract can improve intractable neurogenic symptoms. Feb 01, 2003

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Pubmed Data : Clin Rehabil. 2003 Feb;17(1):21-9. PMID: 12617376

Article Published Date : Feb 01, 2003

Study Type : Human Study

Additional Links

Substances : Marijuana

Diseases : Brachial Plexus Neuropathies, Multiple Sclerosis, Neurogenic Bladder, Phantom Limb, Spinal Cord Injuries

[+]

Anandamide is a potent and selective inhibitor of the proliferation of breast cancer cells.Jul 06, 1998

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Proc Natl Acad Sci U S A. 1998 Jul 7 ;95(14):8375-80. PMID: 9653194

Article Published Date : Jul 06, 1998

Study Type : Human In Vitro

Additional Links

Substances : Anandamide, Cannabinoids

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative

Additional Keywords : Cannabinoid Receptors, Dose Response

[+]

Cannabidiol causes vasorelaxation of the human mesenteric artery.Aug 31, 2015

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Pubmed Data : Cardiovasc Res. 2015 Sep 1 ;107(4):568-78. Epub 2015 Jun 19. PMID: 26092099

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Pubmed Data : J Pharm Pharmacol. 2004 Mar ;56(3):291-7. PMID: 15025853

Article Published Date : Feb 29, 2004

Study Type : Human In Vitro

Additional Links

Substances : Cannabidiol, Cannabinoids

[+]

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Pubmed Data : Mol Pharmacol. 2006 Nov ;70(5):1612-20. Epub 2006 Aug 25. PMID: 16936228

Article Published Date : Oct 31, 2006

Study Type : Human In Vitro

Additional Links

Substances : Cannabinoids , Cannabinoids: Synthetic

Diseases : Lymphoma

Pharmacological Actions : Apoptotic, P38 Mitogen-Activated Protein Kinase Modulator

Additional Keywords : Selective Cytotoxicity

[+]

The proapoptotic effect of cannabinoids on tumor cells is mediated by a ceramide dependent upregulation of the stress protein p8.Mar 31, 2006

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Pubmed Data : Australas Psychiatry. 2016 Aug 24. Epub 2016 Aug 24. PMID: 27558217

Article Published Date : May 05, 2017

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Epilepsy

Pharmacological Actions : Anticonvulsants

[+]

Insights on cannabidiol's antiallodynic and anxiolytic mechanisms of action in a model of neuropathic pain.Aug 31, 2019

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Pubmed Data : Eur J Pharmacol. 2006 Aug 7;542(1-3):100-5. Epub 2006 May 20. PMID: 16781706

Article Published Date : Aug 07, 2006

Study Type : Animal Study

Additional Links

Substances : Cannabinoids

Diseases : Amyotrophic Lateral Sclerosis

Pharmacological Actions : Neuroprotective Agents

[+]

A cannabinoid type 1 receptor antagonist improves sodium balance and delays decompensation in preascitic cirrhosis. Jul 01, 2009

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Pubmed Data : Gastroenterology. 2009 Jul;137(1):341-9. Epub 2009 Jan 14. PMID: 19208344

Article Published Date : Jul 01, 2009

Study Type : Animal Study

Additional Links

Substances : Cannabis

Diseases : Ascites

[+]

A cannabis extract with high content in cannabidiol attenuated chemically-induced intestinal inflammation.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Neurotox Res. 2017 Sep 21. Epub 2017 Sep 21. PMID: 28933048

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Pubmed Data : Glia. 2009 Oct ;57(13):1374-85. PMID: 19229996

Article Published Date : Sep 30, 2009

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Delta-tetrahydrocannabinol (THC)

Diseases : Gliomas

Pharmacological Actions : Antineoplastic Agents, Apoptotic

[+]

An extract of fructus cannabis ameliorates learning and memory impairment induced by d-galactose.Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Neuropathol Exp Neurol. 2018 Aug 28. Epub 2018 Aug 28. PMID: 30169677

Article Published Date : Aug 27, 2018

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Epilepsy

Pharmacological Actions : Anticonvulsants

[+]

Anticonvulsive properties of cannabidiol in a model of generalized seizure are transient receptor potential vanilloid 1 dependent.May 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cannabis Cannabinoid Res. 2020 Jun 1 ;5(2):145-149. Epub 2020 Jun 5. PMID: 32656346

Article Published Date : May 31, 2020

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Lennox-Gastaut Syndrome

Pharmacological Actions : Anticonvulsants

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View the Evidence: 920 Abstracts with Cannabis Research

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A review and meta-analysis of the efficacy and safety of cannabidiol in epilepsy.Nov 02, 2018

A systematic review and meta-analysis off the effects of cannabinoids in Amyotrophic lateral sclerosis murine models.Dec 05, 2018

Adjunctive CBD resulted in a greater reduction in convulsive seizure frequency.Feb 09, 2020

Cannabinoids have therapeutic value in chronic non-cancer pain. Jul 01, 2009

Cannabinoids may have possible therapeutic properties for the management of the multiple sclerosis.Nov 19, 2010

Cannabinoids significantly reduced infarct volume and improve functional outcome in experimental stroke models.Feb 28, 2015

Recently active cannabis smoking and diabetes mellitus are inversely associated. May 13, 2015

Selective cannabinoids provide a small analgesic benefit in patients with chronic neuropathic pain.May 18, 2017

The median effective dose of morphine administered in combination with THC is 3.6 times lower than of morphine alone.Mar 21, 2017

This meta-analysis and systematic review has highlighted the haemodynamic effects of CBD.Dec 31, 2016

Whole plant cannabis provides subjective symptom relief in multiple sclerosis. Jan 01, 2009

"Low-Dose Vaporized Cannabis Significantly Improves Neuropathic Pain."Dec 09, 2012

A case report of a female patient who demonstrated disease response after declining standard therapy and taking a combination of Laetrile and CBD oil.Jul 31, 2019

A hemp seed containing proprietary Chinese herbal medicine alleviates symptoms of functional constipation.Nov 02, 2010

A low dose of THC produces subjective stress-relieving effects in line with those commonly reported among cannabis users.May 29, 2017

A positive THC screen is associated with decreased mortality in adult patients sustaining traumatic brain injury.Sep 30, 2014

A single dose of cannabidiol reduces blood pressure in healthy volunteers.Jun 14, 2017

A single-dose treatment with Delta(9)-THC is effective and safe in treating tics and obsessive-compulsive disorder in Tourette Syndrome.Sep 24, 2008

A tetrahydrocannabinol:cannabidiol (THC:CBD) extract is efficacious for relief of pain in patients with advanced cancer pain not fully relieved by strong opioids.Jul 01, 2009

Acute cannabidiol administration at a dose of 300 mg decreased anxiety in patients with Parkinson's disease.Jan 06, 2020

Add-on cannabidiol may be an efficacious long-term treatment option for treatment-resistant epilepsies.Jul 11, 2018

Adding medical cannabis oil to AD patients' pharmacotherapy is safe and a promising treatment option.Jan 11, 2016

Cannabidiol acts at 5-HT 1A receptors in the human brain: Relevance for treating temporal lobe epilepsy. Dec 31, 2019

Cannabidiol attenuates insular dysfunction during motivational salience processing in subjects at clinical high risk for psychosis.Aug 21, 2019

Cannabidiol could be useful in Dravet syndrome treatments. Mar 31, 2016

Cannabidiol could reduce severe behavioural problems in children and adolescents with intellectual disability. May 31, 2020

Cannabidiol for rapid eye movement sleep behavior disorder. Mar 21, 2021

Cannabidiol for the treatment of crack-cocaine craving.Oct 29, 2020

Cannabidiol for treating drug-resistant epilepsy in children.Aug 12, 2018

Cannabidiol for treating Lennox-Gastaut Syndrome and Dravet Syndrome in Korea Dec 27, 2020

Cannabidiol has antipsychotic properties which balance out the psychotomimetic effects of THC in cannabis.Apr 01, 2008

Cannabidiol improves frequency and severity of seizures and reduces adverse events.Aug 08, 2018

Cannabidiol in the treatment of post-traumatic stress disorder.Dec 12, 2018

Cannabidiol levels in different strains of cannabis may determine the degree to which THC interferes with memory in users.Oct 01, 2010

Cannabidiol may be an effective and well-tolerated treatment option for patients with refractory seizures in Tuberous sclerosis complex.Sep 30, 2016

Cannabidiol may hold benefit for anxiety-related disorders. Dec 31, 2018

Cannabidiol might reduce seizure frequency and might have an adequate safety profile in children and young adults with treatment-resistant epilepsy.Dec 22, 2015

Cannabidiol reduces anxiety in social anxiety disorder through modulating the limbic and paralimbic brain areas. Sep 09, 2010

Cannabidiol resulted in a greater reduction in convulsive-seizure frequency among patients with Dravet syndrome.Jan 24, 2017

Cannabidiol treatment in children with treatment resistant epilepsies led to 42% of children reporting a greater than 80% reduction in seizure frequency and 32% reporting a 25-60% seizure reduction.Nov 30, 2013

Cannabidiol treatment yielded a significant positive effect on seizure load in patients with intractable epilepsy.Jan 05, 2016

Cannabinoid treatment for autism: a proof-of-concept randomized trial.Feb 02, 2021

Cannabinoids may have a therapeutic role to play in treating mantle cell lymphoma. Jul 01, 2009

Cannabinoids may have therapeutic value in the treatment of tics in Tourette syndrome. Oct 01, 2003

Cannabis analgesia in chronic neuropathic pain is associated with altered brain connectivity.Sep 04, 2018

Cannabis and cannabinoids in cancer pain management.May 31, 2020

Cannabis appears to have some therapeutic value (based on self-reporting) amongst patients with inflammatory bowel disease.Jul 26, 2011

Cannabis cigarettes may be effective at ameliorating neuropathic pain. Jun 01, 2008

Cannabis could be potentially beneficial reduction in systemic inflammation and immune activation in the context of antiretroviral-treated HIV infection.Feb 16, 2018

Cannabis extract is safe and efficacious in reducing chemotherapy-induced nauseau and vomiting.Nov 01, 2010

Cannabis extracts can be a useful and safe option for patients with MS with moderate to severe spasticity resistant to common antispastic drugs.May 08, 2016

Cannabis extracts can be considered an alternative in patients with spasticity associated with chronic spinal cord injury.Sep 30, 2017

Cannabis in ASD patients appears to be well tolerated, safe and effective option to relieve symptoms associated with ASD.Jan 16, 2019

Cannabis is well tolerated and effective in the treatment of HIV-associated neuropathyFeb 13, 2007

Cannabis is well-tolerated and efficacious in the treatment of neuropathic pain from brachial plexus avulsion.Dec 01, 2004

Cannabis may have a beneficial impact on HIV-associated blood-brain barrier injury.Apr 15, 2020

Cannabis may have therapeutic value in the treatment of Tourette syndrome.Dec 01, 1998

Cannabis may improve pain, mood and sleep in some patients with chronic pain.Jun 01, 2002

Cannabis reduces symptoms in patients with fibromyalgia. Jan 01, 2011

Cannabis reverses exercise-induced asthma and hyperinflation in subjects with clinically stable bronchial asthma. Sep 01, 1975

Cannabis seeds extract could be used in the treatment of acne vulgaris, seborrhea, papules and pustules.Jun 30, 2015

Cannabis significantly reduces the use of prescription opioids and improves quality of life.Dec 26, 2020

Cannabis use by inflammatory bowel disease patients can induce clinical improvement and is associated with reduced use of medication and slight weight gain.Oct 31, 2019

Cannabis use is associated with a lower insulin resistance risk in HIV-HCV-coinfected patients.Jun 30, 2015

Cannabis use is associated with a lower rate of obesity in young adults. Oct 12, 2010

Cannabis use may reduce healthcare utilization and improve hospital outcomes in patients with cirrhosis.Nov 02, 2020

Cannabis use significantly reduces symptoms, and reduces the requirements for drugs and surgery in subjects with Crohn's disease. Aug 01, 2011

Cannabis users report greater pain relief in combination with opioids than when opioids are used alone.Jan 31, 2015

Cannabis was associated with a decreased risk of Clostridioides difficile Infection amongst hospitalized patients.Sep 03, 2019

Cannabis, used with adequate precaution, appears to be moderately efficacious for the treatment of chronic pain. Sep 01, 2009

Cannabis-based extracts have therapeutic value for bladder dysfunction in advanced mutiple sclerosis. Aug 01, 2004

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View the Evidence:
920 Abstracts with Cannabis Research