Cannabis

Name	AC	CK
Multiple Sclerosis	54	468
Epilepsy	62	333
Neuropathic Pain	32	223
Inflammation	80	203
Anxiety	32	189
Tourette Syndrome	10	161
Chronic Pain	27	130
Inflammatory Bowel Diseases	18	119
Parkinson's Disease	33	109
Pain	10	107
Autism Spectrum Disorders	13	92
Cancers: All	49	82
Sleep Disorders	9	81
Epilepsy: Childhood	6	76
Seizures	12	68
Hypertension	10	66
Insomnia	7	65
Dravet syndrome	8	64
Oxidative Stress	34	61
Alzheimer's Disease	35	60
Obesity	16	58
Fibromyalgia	8	57
Huntington Disease	11	56
Neurodegenerative Diseases	35	56
Breast Cancer	34	55
HIV Infections	10	54
Morphine Tolerance/Dependence	8	54
Brain Inflammation	32	52
Spinal Cord Injuries	7	51
Glioblastoma Multiforme	13	50
Glioma	23	50
Stroke: Attenuation/Recovery	6	49
Lipopolysaccharide-Induced Toxicity	25	46
Obsessive-Compulsive Disorder	4	45
Stroke	5	45
Anxiety Disorders	9	40
Brachial Plexus Neuropathies	2	40
Cancer: Pain	7	40
Opioid Tolerance/Dependence	1	40
Memory Disorders	8	38
Depression	17	36
Lennox-Gastaut Syndrome	8	36
Diabetes Mellitus: Type 2	9	35
Bladder Dysfunction	3	34
Muscle Spasticity	3	34
Post-Traumatic Stress Disorders (PTSD)	13	33
Schizophrenia	17	33
Dementia	7	32
Lung Cancer	18	32
Marijuana Addiction/Withdrawal	3	32
Nonalcoholic fatty liver disease (NAFLD)	5	32
Hyperalgesia	11	31
Attention Deficit Hyperactivity Disorder	2	30
Overactive Bladder	1	30
Arthritis	6	29
Stroke: Ischemic	4	29
Acne	6	28
Coronavirus Infection	21	28
Colitis	10	27
Diabetic Neuropathies	3	26
Amyotrophic lateral sclerosis (ALS)	4	25
Cancer Metastasis	11	25
Glioblastoma	15	25
Psychoses	7	25
Glaucoma	6	23
Psychiatric Disorders	11	23
Head and Neck Cancer	3	22
Allodynia	7	21
Amyotrophic Lateral Sclerosis	10	21
Breast Cancer: Triple Negative	11	21
Lymphoma	5	21
Diabetes	1	20
Headache: Migraine	2	20
Hypoglycemia	1	20
Impairment: Driving Related	1	20
Incontinence	1	20
Liver Cancer	8	20
Peripheral Nerve Diseases	1	20
Social Anxiety Disorder (SAD)	1	20
Sturge-Weber Syndrome	2	20
Vaccine-induced Toxicity	1	20
Brain Cancer	4	19
Chemotherapy-Induced Toxicity: Cisplatin	8	19
Colon Cancer	11	19
Lipid Peroxidation	5	19
Prostate Cancer	15	19
Brain Ischemia	8	17
Colorectal Cancer	13	17
Constipation	4	17
Metabolic Diseases	3	17
Ovarian Cancer	5	17
Brain: Microglial Activation	6	16
Cerebral Ischemia	7	16
Fatigue	3	16
Atherosclerosis	4	15
Ulcerative Colitis	2	15
Astrocytoma	4	14
Brain Injury: Traumatic	3	14
Metabolic Syndrome X	2	14
Pancreatic Cancer	10	14
Autoimmune Diseases	8	13
Brain Damage: Hypoxic Ischemic Insult	6	13
Diabetic Complications	7	13
Encephalopathy	2	13
Melanoma	8	13
Rheumatoid Arthritis	4	13
Cardiovascular Diseases	6	12
Cognitive Decline/Dysfunction	6	12
Epileptic Seizures	2	12
Hepatitis C	3	12
Insulin Resistance	2	12
Muscle Damage: Exercise-Induced	2	12
Periodontitis	2	12
Rett Syndrome	2	12
Skin Cancer	5	12
Chemotherapy-Induced Toxicity: Paclitaxel	4	11
Chronic Pelvic Pain Syndrome	2	11
Cirrhosis	2	11
Clostridium Infections	2	11
Endocannabinoid Disorders	2	11
Migraines	2	11
Myocardial Infarction	4	11
Nausea: Chemotherapy-Induced	2	11
Opiate Addiction/Withdrawal	2	11
Anorexia: Dementia-Associated	1	10
Bronchial Asthma	1	10
C-Reactive Protein (CRP)	1	10
Chemotherapy	1	10
Chemotherapy-Induced Toxicity	1	10
Child Behavior Disorders	1	10
Cocaine Addiction	1	10
Crack Addiction/Withdrawal	1	10
Delirium: Drug-Induced	1	10
Dry Skin	1	10
Gastrointestinal Inflammation	4	10
Gastroparesis	1	10
Heroin Addication/Withdrawal	1	10
Learning disorders	1	10
Low Back Pain	1	10
Lymphoma: Mantle Cell	1	10
Multiple Sclerosis: Relapsing-Remitting	1	10
Myocardial Ischemia	3	10
Nausea: Pregnancy-Associated	1	10
Neurogenic Bladder	1	10
Neuropathic Pain: HIV-associated	1	10
Neuropathy: HIV associated	1	10
Organ Transplantation: Kidney	1	10
Osteoarthritis	7	10
Osteoarthritis: Knee	1	10
Overweight	1	10
Pancreatitis: Chronic	1	10
Phantom Limb	1	10
Quality of Life: Poor	1	10
Rheumatic Diseases	1	10
Seborrheic Dermatitis	1	10
Sitting Sickness	1	10
Stress	1	10
Temporal Lobe Epilepsy (TLE)	1	10
Temporomandibular Joint Disorders	1	10
Testosterone: Too Low	1	10
Tuberous Sclerosis	1	10
Ulcer: Aphthous	1	10
Endocannabinoid System	7	9
Sepsis	4	9
Alcohol Toxicity	4	8
Bladder Cancer	6	8
Colon Cancer: Prevention	2	8
Diabetes Mellitus: Type 1	4	8
Endotoxemia	2	8
Middle Cerebral Artery Occlusion (MCAO)	4	8
Psoriasis	6	8
Staphylococcus aureus infection	6	8
Traumatic Memory Formation	4	8
Alcoholic Liver Disease	2	7
Brain: Oxidative Stress	3	7
Cholangiocarcinoma	2	7
High Fat Diet	4	7
Hydrogen Peroxide Induced Toxicity	6	7
Liver Fibrosis	3	7
Oral Mucositis	4	7
Psychiatric Disorder: Conditioned Fear	4	7
Aging: Brain	3	6
Alcohol Withdrawal	2	6
Astrocytoma: Grade IV	1	6
Attention Deficit Disorder with Hyperactivity	1	6
Cachexia	4	6
Chemotherapy-Induced Toxicity: Doxorubicin	4	6
Chemotherapy-Induced Toxicity: Peripheral Neuropathy	3	6
Dermatitis	2	6
Diabetes Mellitus: Type 1: Prevention	3	6
Diabetes: Cataract	2	6
Emesis	1	6
Epidermolysis Bullosa	1	6
Hypersensitivity	2	6
Hypertension: Pulmonary	3	6
Multiple Myeloma	3	6
Neuroblastoma	3	6
Traumatic Brain Injury	3	6
Vomiting	1	6
Wound Healing	4	6
Acute Myeloid Leukemia	2	5
Asthma	3	5
Chemotherapy and Radiation Toxicity	2	5
Chemotherapy-Induced Nausea	3	5
Drug Abuse	3	5
Encephalomyelitis	3	5
Gliomas	3	5
Headache	3	5
Hyperglycemia	2	5
Leukemia	4	5
Psychotic Disorders	4	5
Staphylococcus aureus: Methicillin-resistant (MRSA)	3	5
Thyroid Cancer	3	5
Tremor	2	5
AIDS	2	4
Acute Respiratory Distress Syndrome	2	4
Allergic Airway Diseases	2	4
Aluminum Toxicity	1	4
Appetite Disorders: Loss/Lack of	1	4
Arteriosclerosis	1	4
Bone Fractures	2	4
Brain Damage	3	4
Breast Cancer: Lung Metastasis	1	4
Breast Cancer: Prevention	1	4
Cachexia: Cancer	3	4
Cancers: Drug Resistant	3	4
Cardiac Arrhythmias	1	4
Cervical Cancer	2	4
Chemotherapy-Induced Toxicity: Oxaliplatin	1	4
Chemotherapy-Induced Toxicity: Vincristine	1	4
Cocaine Toxicity	2	4
Coronavirus Disease (Covid-19)	4	4
Endothelial Dysfunction	2	4
Eye Damage	1	4
Febrile Seizures	2	4
Fulminant Hepatic Failure	1	4
Heart Failure	2	4
Hepatic Encephalopathy	1	4
High Cholesterol	2	4
Immune Disorders: Low Immune Function	1	4
Iron Overload	2	4
Irritable Bowel Syndrome	3	4
Ischemia	2	4
Liver Damage	2	4
Liver Failure: Acute	1	4
Low Immune Function: Splenic Dysfunction	1	4
Rhabdomyosarcoma	1	4
Uveitis	1	4
Acute T cell Leukemias	2	3
Acute lymphoblastic leukemia (ALL)	2	3
Aging	2	3
Atopic Dermatitis	2	3
Autism	2	3
Bipolar Disorder	1	3
Breast Cancer: Metastatic	2	3
Carcinoma: Non-Small-Cell Lung	2	3
Central Nervous System Diseases	2	3
Cough	1	3
Drug Addiction	2	3
Endometrial Cancer	1	3
Epilepsy: Infant	1	3
Epilepsy: Malignant Migrating Partial Seizures	1	3
Escherichia coli Infections	3	3
Fibrosis	2	3
Gastric Cancer	3	3
Gastrointestinal Diseases	2	3
Gram-Positive Bacterial Infections	3	3
Immune Disorders	2	3
Lichenoid Dermatitis	1	3
Malaria	2	3
Neuralgia	1	3
Neurologic Disorders	2	3
Osteoporosis	3	3
Osteosarcoma	2	3
Squamous cell carcinoma	1	3
Trigeminal Neuralgia	2	3
Aging Skin	1	2
Air Pollution Linked Toxicity	1	2
Alcohol Addiction	2	2
Amphetamine Addiction/Withdrawal	1	2
Angelman Syndrome	1	2
Animal Diseases: Simian Immunodeficiency Virus (SIV)	1	2
Ascites	1	2
Brain Edema	1	2
Cachexia: Chemotherapy Induced	1	2
Cancers: Canine	1	2
Candida Albicans	2	2
Candida Infection	1	2
Cardiomyopathy	1	2
Cat Diseases	1	2
Cerebral Hypoperfusion	1	2
Chemically-Induced Liver Damage	1	2
Chemotherapy-Induced Toxicity: Cyclophosphamide	1	2
Chemotherapy-Induced Toxicity: 5-fluorouracil	1	2
Cocaine Withdrawal	1	2
Degenerative Disk Disease	1	2
Depression	1	2
Depressive Disorder	1	2
Dermatitis: Contact	1	2
Diabetes: Cardiovascular Illness	1	2
Diabetes: Memory Problems	1	2
Diabetes: Oxidative Stress	1	2
Diabetic Neuropathy	1	2
Diabetic Retinopathy	1	2
Diarrhea	1	2
Dog Diseases	1	2
Drug-Induced Toxicity: Epilepsy Drugs	1	2
Drug-Induced Toxicity: Methotrexate	1	2
Dysbiosis	1	2
Epilepsy: Drug-Induced	1	2
Estrogen Deficiency	1	2
Fatigue: Excercise-Induced	1	2
Fatty Liver	1	2
Friedreich Ataxia	1	2
Gastroschisis	1	2
Gram-Negative Bacterial Infections	2	2
Heart Attack	1	2
Hypercholesterolemia	1	2
Hypersensitivity: Type IV	1	2
Hypothermia	1	2
Hypothyroidism	1	2
Hypoxia	1	2
Immune Dysregulation: TH1/TH2 imbalance	1	2
Infant Neurological Development	1	2
Inflammation: Neutrophil-Mediated	1	2
Influenza	2	2
Interstitial Lung Diseases	1	2
Leishmaniasis	1	2
Listeria Infections	1	2
Liver Cirrhosis	1	2
Liver Damage: Drug-Induced	1	2
Liver Disease	1	2
Liver Injury: Ischemia/reperfusion	1	2
Lung Inflammation	1	2
Memory Disorders: Drug-Induced	1	2
Menopausal Syndrome	1	2
Mesothelioma	1	2
Mitochondrial Dysfunction	1	2
Mood Disorders	1	2
Muscle Soreness	1	2
Myocardial Fibrosis	1	2
Myocarditis: Autoimmune	1	2
Neonatal Stroke	1	2
Neurological Conditions	2	2
Oral Cancer	1	2
Peripheral Neuropathies	1	2
Phencyclidine (PCP) Induced Toxicity	1	2
Postmenopausal Disorders	1	2
Prenatal Chemical Exposures	1	2
Prion Diseases	1	2
Pseudomonas aeruginosa	1	2
Salmonella Infections	1	2
Sciatic Nerve Crush Injury	1	2
Skin Diseases: Inflammatory	1	2
Spinal Cord Inflammation	1	2
Streptococcus pyogenes	1	2
Tardive Dyskinesia	1	2
Tumors	2	2
Ultraviolet Radiation Induced Damage	2	2
Urinary Bladder Diseases	1	2
Vitamin D Deficiency	1	2
Acetaminophen (Tylenol) Toxicity	1	1
Acinetobacter baumannii infection	1	1
Acquired Immunodeficiency Syndrome	1	1
Allergies	1	1
Anorexia	1	1
Appetite Disorders	1	1
Arrhythmias: Cardiac	1	1
Arthritis: Rheumatoid	1	1
Auditory Diseases	1	1
Bone Diseases	1	1
Bronchial Diseases	1	1
Burkitt Lymphoma	1	1
Cadmium Poisoning	1	1
Cancers	1	1
Cancers: Multi-Drug Resistant	1	1
Cardiovascular Disease: Prevention	1	1
Diabetes: Cognitive Dysfunction	1	1
Drug Toxicity: Methotrexate	1	1
Dry Eye Syndromes	1	1
Dystonia	1	1
Ebola Virus Infections	1	1
Eczema	1	1
Epstein-Barr Virus Infections	1	1
Eye Diseases	1	1
Gynecomastia	1	1
Hepatitis	1	1
Hepatitis: Autoimmune	1	1
Herpes Simplex Virus Type 2	1	1
Herpes family viruses	1	1
Herpes: Kaposi-Associated	1	1
High Sugar Diet	1	1
Hypotension	1	1
Intestinal Permeability	1	1
Joint Diseases	1	1
Kaposi Disease	1	1
Kaposi's Sarcoma	1	1
Kidney Cancer	1	1
Kidney Damage	1	1
Leukemia: T-cell acute Lymphoblastic	1	1
Lung Injury: Acute	1	1
Methicillin-resistant Staphylococcus aureus	1	1
Migraine Disorders	1	1
Movement Disorders	1	1
Mycobacterium Tuberculosis	1	1
Oncovirus	1	1
Pesticide Toxicity	1	1
Plasmodium Infections	1	1
Prostate: PSA Doubling	1	1
Prostatitis: Chronic	1	1
Pruritus	1	1
Radiation	1	1
Skin Diseases	1	1
Subarachnoid hemorrhage	1	1
Testicular Cancer	1	1
Thymoma	1	1
Tobacco Addiction/Withdrawal	1	1
Zika Virus	1	1

Name	AC	CK
Anti-Inflammatory Agents	216	586
Neuroprotective Agents	196	550
Analgesics	89	549
Anticonvulsants	71	425
Apoptotic	124	219
Anti-Anxiety Agents	41	216
Antiproliferative	104	206
Antioxidants	80	155
Immunomodulatory	40	110
Tumor Necrosis Factor (TNF) Alpha Inhibitor	43	91
Antidepressive Agents	22	82
Anti-metastatic	37	75
Antihypertensive Agents	9	63
Antinoceceptive	18	60
Interleukin-6 Downregulation	26	60
Angiogenesis Inhibitors	20	53
Chemopreventive	14	53
Cyclooxygenase 2 Inhibitors	15	53
Antineoplastic Agents	31	50
Chemotherapeutic	26	48
Interleukin-1 beta downregulation	23	45
Vasodilator Agents	7	43
NF-kappaB Inhibitor	20	33
Hepatoprotective	14	32
Anti-Apoptotic	17	30
Cardioprotective	15	29
Gastrointestinal Agents	13	29
Hypoglycemic Agents	5	29
Chemoprotective Agents	11	26
Autophagy Up-regulation	11	25
Superoxide Dismutase Up-regulation	7	25
Antispasmodic	2	24
Antiviral Agents	20	24
Immunosuppressive Agents	8	23
Vascular Endothelial Growth Factor Inhibitors	4	23
Matrix metalloproteinase-9 (MMP-9) inhibitor	2	22
Anxiolytic	2	21
Cell cycle arrest	13	20
Enzyme Inhibitors	5	19
Interleukin-8 downregulation	7	19
Anti-Bacterial Agents	13	18
Anti-Tumor	9	17
Chemosensitizer	12	17
Hypolipidemic	7	17
Neurogenesis	8	15
Anticarcinogenic Agents	8	14
Gastroprotective	3	14
Osteoprotective	4	14
Brain-derived neurotrophic factor modulator	7	13
Interferon Gamma Reducer	6	13
Interleukin-10 upregulation	6	13
Antipsychotic Agents	8	12
MicroRNA modulator	6	12
Nitric Oxide Inhibitor	5	12
Anti-Fibrotic	6	11
Antiemetics	1	10
Bronchodilator Agents	1	10
GABA Modulators	1	10
Immunomodulatory: Th17 downregulation	4	9
Nrf2 activation	7	9
Appetite Stimulants	3	8
Prostaglandin PGE2 downregulation	2	8
Anti-Angiogenic	6	7
Cannabinoid Receptor Antagonist/Inverse Agonist	3	7
Cytotoxic	3	7
P38 Mitogen-Activated Protein Kinase Modulator	2	7
Catalase Up-Regulation	2	6
Interleukin-10 downregulation	2	6
Interleukin-17 downregulation	4	6
Radiosensitizer	3	6
Tumor Suppressor Protein p53 Upregulation	4	6
Vascular Cell Adhesion Molecule-1 Inhibitor	2	6
Interleukin-4 downregulation	3	5
Laxative	2	5
Neuritogenic	3	5
Prophylactic Agents	4	5
Anti-atherogenic	1	4
Anticholesteremic Agents	2	4
Antifungal Agents	3	4
Antimicrobial	3	4
Bcl-2 protein down-regulation	2	4
Caspase-3 Activation	3	4
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor	1	4
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	4	4
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	4
Matrix metalloproteinase-2 (MMP-2) inhibitor	2	4
Pancreato Protective Agents	2	4
Vascular Endothelial Growth Factor A Inhibitor	2	4
Vascular Endothelial Growth Factor Regulator	2	4
Acetylcholinesterase Inhibitor	2	3
Aldose reductase inhibitor	1	3
Alpha-glucosidase inhibitor	1	3
Cyclooxygenase 1 Inhibitor	3	3
Interleukin-12 downregulation	2	3
Interleukin-2 Downregulation	2	3
Renoprotective	2	3
Sedative effects	1	3
Vanilloid Receptor-1 Modulator	1	3
Anti-Androgen	1	2
Anti-Cachexic Agents	2	2
Anti-Infective Agents	1	2
Anti-Platelet	1	2
Calcium Channel Blockers	1	2
Chondroprotective	1	2
Cyclooxygenase Inhibitors	1	2
Enzyme Activators	1	2
Epidermal growth factor receptor (EGFR) inhibitor	1	2
Glycine Agents	1	2
Heme oxygenase-1 inducer	1	2
Heme oxygenase-1 up-regulation	1	2
Hypnotics and Sedatives	1	2
Immunomodulatory: T-Cell down-regulation	1	2
Immunostimulatory	1	2
Interleukin-5 downregulation	1	2
Intracellular adhesion molecule-1 (ICAM-1)	1	2
Malondialdehyde Down-regulation	1	2
Neuroplasticity enhancement	1	2
Photoprotective	2	2
Platelet Aggregation Inhibitors	1	2
Redox Modulator	1	2
Regenerative	1	2
STAT3 Inhibitor	1	2
Topoisomerase II Inhibitor	2	2
Transforming growth factor beta (TGF-β) inhibitor	1	2
Vasoprotective	1	2
Wnt/β-catenin signaling pathway modulation	2	2
interleukin-13 down-regulation	1	2
5-Lipoxygenase Inhibitor	1	1
Angiotensin-Converting Enzyme Inhibitors	1	1
Anti-Allergic Agents	1	1
Anti-Proliferative	1	1
Anti-Psychotic	1	1
Antimalarials	1	1
Antimutagenic Agents	1	1
Caspase-8 activation	1	1
Caspase-9 Activation	1	1
Heat Shock Protein Down-Regulation	1	1
Interleukin-1 alpha downregulation	1	1
Interleukin-18 upregulation	1	1
Interleukin-2 upregulation	1	1
Interleukin-4 upregulation	1	1
Interleukin-6 upregulation	1	1
NADPH Oxidase Inhibitors	1	1
Neuroimmunomodulation	1	1
Paraptosis	1	1
Phase II Detoxification Enzyme Inducer	1	1
Radioprotective	1	1
Transient receptor potential vanilloid type-2 activation	1	1
apoptosis	1	1

[+]

Cannabinoids are a safe and effective treatment for Tourette syndrome and should be considered in treatment-resistant cases.Aug 23, 2016

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Pubmed Data : Australas Psychiatry. 2016 Aug 24. Epub 2016 Aug 24. PMID: 27558217

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2022 ;13:908198. Epub 2022 May 9. PMID: 35614947

Article Published Date : May 05, 2017

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Epilepsy

Pharmacological Actions : Anticonvulsants

[+]

Insights on cannabidiol's antiallodynic and anxiolytic mechanisms of action in a model of neuropathic pain.Aug 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pain Rep. 2019 Sep-Oct;4(5):e774. Epub 2019 Aug 13. PMID: 32766463

Article Published Date : Aug 31, 2019

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Neuropathic Pain

Pharmacological Actions : Anti-Anxiety Agents, Antinoceceptive

[+]

Vasorelaxant effect of Moroccan Cannabis sativa threshing residues on rat mesenteric arterial bed is endothelium and muscarinic receptors dependent.Dec 31, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Eur J Pharmacol. 2006 Aug 7;542(1-3):100-5. Epub 2006 May 20. PMID: 16781706

Article Published Date : Aug 07, 2006

Study Type : Animal Study

Additional Links

Substances : Cannabinoids

Diseases : Amyotrophic Lateral Sclerosis

Pharmacological Actions : Neuroprotective Agents

[+]

A cannabinoid type 1 receptor antagonist improves sodium balance and delays decompensation in preascitic cirrhosis. Jul 01, 2009

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Pubmed Data : Gastroenterology. 2009 Jul;137(1):341-9. Epub 2009 Jan 14. PMID: 19208344

Article Published Date : Jul 01, 2009

Study Type : Animal Study

Additional Links

Substances : Cannabis

Diseases : Ascites

[+]

A cannabis extract with high content in cannabidiol attenuated chemically-induced intestinal inflammation.Dec 31, 2015

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Pubmed Data : Biochem Pharmacol. 2013 Jun 1 ;85(11):1626-33. Epub 2013 Mar 26. PMID: 23537701

Article Published Date : May 31, 2013

Study Type : Animal Study

Additional Links

Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC)

Diseases : Myocardial Infarction, Myocardial Ischemia

Pharmacological Actions : Cardioprotective, Neuroprotective Agents

[+]

A synthetic cannabinoid inhibited CXCL12-induced migration and invasive properties of breast cancer cells.Dec 31, 2010

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Neurotox Res. 2017 Sep 21. Epub 2017 Sep 21. PMID: 28933048

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Pubmed Data : Glia. 2009 Oct ;57(13):1374-85. PMID: 19229996

Article Published Date : Sep 30, 2009

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Delta-tetrahydrocannabinol (THC)

Diseases : Gliomas

Pharmacological Actions : Antineoplastic Agents, Apoptotic

[+]

An extract of fructus cannabis ameliorates learning and memory impairment induced by d-galactose.Dec 31, 2016

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Pubmed Data : Inflammopharmacology. 2018 Oct 5. Epub 2018 Oct 5. PMID: 30291491

Article Published Date : Oct 04, 2018

Study Type : Animal Study

Additional Links

Substances : Cannabidiol, Cannabis

Diseases : Multiple Sclerosis

Pharmacological Actions : Immunomodulatory

Additional Keywords : Natural Substances Versus Drugs

[+]

Broad-spectrum cannabis oil ameliorates reserpine-induced fibromyalgia model in mice.Sep 30, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Pharmacother. 2022 Oct ;154:113552. Epub 2022 Aug 18. PMID: 35988425

Article Published Date : Sep 30, 2022

Study Type : Animal Study

Additional Links

Substances : Cannabis

Diseases : Fibromyalgia, Hyperalgesia

Pharmacological Actions : Analgesics

[+]

[+]

Click here to read the entire abstract

Pubmed Data : Brain Behav Immun. 2024 May 15 ;119:945-964. Epub 2024 May 15. PMID: 38759736

Article Published Date : May 14, 2024

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Brain Inflammation , Post-Traumatic Stress Disorders (PTSD)

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

[+]

[+]

Cannabidiol controls the exaggerated inflammatory response observed in an animal model of asthma.Dec 31, 2014

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Pubmed Data : Behav Pharmacol. 2020 May 29. Epub 2020 May 29. PMID: 32483052

Cannabidiol enhanced the ability of THC to inhibit cell proliferation, induce cell cycle arrest and apoptosis.Dec 31, 2009

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Pubmed Data : Mol Cancer Ther. 2010 Jan ;9(1):180-9. Epub 2010 Jan 6. PMID: 20053780

Article Published Date : Dec 31, 2009

Study Type : Animal Study, In Vitro Study

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Substances : Cannabidiol, Delta-tetrahydrocannabinol (THC)

Diseases : Cancer Metastasis, Glioblastoma

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Cannabinoid Receptors, Natural Substance Synergy

[+]

Cannabidiol enhanced the hippocampal immune response and autophagy of APP/PS1 Alzheimer's mice.Dec 31, 2020

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Pubmed Data : Life Sci. 2021 Jan 1 ;264:118624. Epub 2020 Oct 21. PMID: 33096116

Article Published Date : Dec 31, 2020

Study Type : Animal Study

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Substances : Cannabidiol

Diseases : Alzheimer's Disease

Pharmacological Actions : Immunostimulatory, Neuroprotective Agents

[+]

Cannabidiol enhances cytotoxicity of anti-cancer drugs in human head and neck squamous cell carcinoma.Jan 25, 2020

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Pubmed Data : Eur J Pharmacol. 2005 Apr 11 ;512(2-3):199-205. PMID: 15840405

Article Published Date : Apr 10, 2005

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Pharmacological Actions : Antipsychotic Agents

Additional Keywords : Antipsychotic Agents, Cannabidiol, Natural Substances Versus Drugs

[+]

Cannabidiol exhibits anxiolytic-like effects and antipsychotic-like effects.Mar 14, 2024

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Pubmed Data : Neurosci Lett. 2024 Mar 15 ;826:137723. Epub 2024 Mar 11. PMID: 38467272

Article Published Date : Mar 14, 2024

Study Type : Animal Study

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Substances : Cannabidiol

Diseases : Anxiety, Schizophrenia

Pharmacological Actions : Anti-Anxiety Agents

[+]

Cannabidiol improves haloperidol-induced motor dysfunction in zebrafish.Mar 03, 2023

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Pubmed Data : Acta Neuropsychiatr. 2024 May 21:1-30. Epub 2024 May 21. PMID: 38770713

Article Published Date : May 20, 2024

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Brain Inflammation , Parkinson's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

[+]

Cannabidiol improves the cognitive function of SAMP8 AD model mice involving the microbiota-gut-brain axis.Jun 01, 2024

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Pubmed Data : J Toxicol Environ Health A. 2024 Jun 2 ;87(11):471-479. Epub 2024 Apr 9. PMID: 38590254

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Pubmed Data : Br J Pharmacol. 2008 Jul ;154(5):1001-8. Epub 2008 May 12. PMID: 18469842

Article Published Date : Jun 30, 2008

Study Type : Animal Study

Additional Links

Substances : Cannabidiol, Cannabis

Diseases : Inflammatory Bowel Diseases

Pharmacological Actions : Enzyme Inhibitors

Problem Substances : Croton oil

[+]

Cannabidiol may represent a promising new protective strategy against cisplatin-induced nephrotoxicity.Feb 28, 2009

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Pubmed Data : J Mol Med (Berl). 2012 Aug ;90(8):925-34. Epub 2012 Jan 10. PMID: 22231745

Pubmed Data : Addict Biol. 2017 Feb 13. Epub 2017 Feb 13. PMID: 28194850

Article Published Date : Feb 12, 2017

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Alcohol Withdrawal

[+]

Cannabidiol reduces lung injury induced by hypoxic-ischemic brain damage.Apr 06, 2017

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Pubmed Data : Pediatr Res. 2017 Apr 7. Epub 2017 Apr 7. PMID: 28388598

Article Published Date : Apr 06, 2017

Study Type : Animal Study

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Substances : Cannabidiol

Diseases : Brain Damage: Hypoxic Ischemic Insult

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

Additional Keywords : Anti-Inflammatory Agents, Brain Damage: Hypoxic Ischemic Insult, Cannabidiol, Neuroprotective Agents

[+]

Cannabidiol reduces seizures and associated behavioral comorbidities in a range of animal seizure and epilepsy modelsDec 25, 2018

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Cannabidiol treatment significantly reduces the incidence of diabetes in NOD mice.Feb 28, 2006

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Pubmed Data : Autoimmunity. 2006 Mar ;39(2):143-51. PMID: 16698671

Article Published Date : Feb 28, 2006

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Diabetes Mellitus: Type 1: Prevention

Pharmacological Actions : Immunomodulatory, Interferon Gamma Reducer, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Risk Reduction, Significant Treatment Outcome

[+]

cannabidiol was able to produce a significant antitumor activity both in vitro and in vivo.Feb 29, 2004

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Pubmed Data : Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3602-7. Epub 2007 Sep 21. PMID: 17890433

Article Published Date : Dec 01, 2007

Study Type : Animal Study

Additional Links

Substances : Marijuana

Diseases : Myocardial Ischemia

[+]

Cannabidiol, a strategy in aging to improve redox state and immunity in male rats.Nov 14, 2024

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Pubmed Data : Int J Mol Sci. 2024 Nov 15 ;25(22). Epub 2024 Nov 15. PMID: 39596353

Article Published Date : Nov 14, 2024

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Aging, Lipid Peroxidation, Oxidative Stress

Pharmacological Actions : Antioxidants, Immunomodulatory

[+]

Cannabidiol-decorated berberine-loaded microemulsions improve IBS-D therapy.Dec 31, 2022

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Pubmed Data : Int J Nanomedicine. 2023 ;18:2839-2853. Epub 2023 May 30. PMID: 37273286

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Pubmed Data : Br J Pharmacol. 2013 Oct ;170(3):679-92. PMID: 23902406

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Pubmed Data : Mol Cancer Ther. 2009 Jul ;8(7):1838-45. Epub 2009 Jun 9. PMID: 19509271

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Pubmed Data : Mol Cancer Ther. 2014 Dec ;13(12):2955-67. Epub 2014 Nov 14. PMID: 25398831

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Pubmed Data : FASEB J. 2003 Mar ;17(3):529-31. Epub 2003 Jan 2. PMID: 12514108

Article Published Date : Feb 28, 2003

Study Type : Animal Study

Additional Links

Substances : Cannabinoids

Diseases : Cancers: All, Gliomas

Pharmacological Actions : Angiogenesis Inhibitors, Matrix metalloproteinase-2 (MMP-2) inhibitor, Vascular Endothelial Growth Factor Regulator

Additional Keywords : Disease Regression

[+]

Cannabinoids inhibit the growth of melanoma cells but not of normal melanocytes.Nov 30, 2006

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Pubmed Data : FASEB J. 2006 Dec ;20(14):2633-5. Epub 2006 Oct 25. PMID: 17065222

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Pubmed Data : Blood. 2002 Jul 15 ;100(2):627-34. PMID: 12091357

Article Published Date : Jul 14, 2002

Study Type : Animal Study

Additional Links

Substances : Anandamide, Cannabinoids: Synthetic, Delta-tetrahydrocannabinol (THC)

Diseases : Acute lymphoblastic leukemia (ALL)

Pharmacological Actions : Anti-Tumor, Antineoplastic Agents, Antiproliferative , Apoptotic

Additional Keywords : Cannabinoid Receptors, Significant Treatment Outcome

[+]

Cannabinol may have therapeutic value in ameliorating symptoms in ALS. Sep 01, 2005

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Pubmed Data : Amyotroph Lateral Scler Other Motor Neuron Disord. 2005 Sep;6(3):182-4. PMID: 16183560

Article Published Date : Sep 01, 2005

Study Type : Animal Study

Additional Links

Substances : Cannabinoids , Cannabis

Diseases : Amyotrophic Lateral Sclerosis

[+]

Cannabis based medicine could be used as a neuroprotective agent capable of delaying disease progression in Huntington's disease.Aug 31, 2011

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Pubmed Data : J Neurosci Res. 2011 Sep ;89(9):1509-18. Epub 2011 Jun 14. PMID: 21674569

Pubmed Data : Mult Scler Relat Disord. 2015 Nov ;4(6):505-11. Epub 2015 Aug 5. PMID: 26590655

Article Published Date : Oct 31, 2015

Study Type : Animal Study

Additional Links

Substances : Cannabidiol, Cannabis, Delta-tetrahydrocannabinol (THC)

Additional Keywords : Plant Extracts

[+]

Cannabis extracts could be neuroprotective agents, delaying disease progression in a proinflammatory model of Huntington’s disease.May 15, 2012

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Pubmed Data : ACS Chem Neurosci. 2012 May 16 ;3(5):400-6. Epub 2012 Feb 9. PMID: 22860209

Article Published Date : May 15, 2012

Study Type : Animal Study

Additional Links

Substances : Cannabinoids , Cannabis

Diseases : Huntington Disease, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Cannabis extracts have therapeutic potential to slow multiple sclerosis progression and repair the central nervous system.Jun 30, 2015

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Pubmed Data : Br J Pharmacol. 2015 Jul ;172(14):3579-95. Epub 2015 May 20. PMID: 25857324

Article Published Date : Jun 30, 2015

Pubmed Data : Phytother Res. 2008 Aug ;22(8):1017-24. PMID: 18618522

Article Published Date : Jul 31, 2008

Study Type : Animal Study

Additional Links

Substances : Cannabidiol, Cannabinoids , Cannabis

Diseases : Hyperalgesia

Pharmacological Actions : Analgesics

Additional Keywords : Plant Extracts

[+]

Cannabis sativa-based oils against aluminum-induced neurotoxicity.Jun 16, 2023

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Pubmed Data : Sci Rep. 2023 Jun 17 ;13(1):9813. Epub 2023 Jun 17. PMID: 37330587

The Following are Sub-Topics of Cannabis

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View the Evidence: 1192 Abstracts with Cannabis Research

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Cannabinoids are a safe and effective treatment for Tourette syndrome and should be considered in treatment-resistant cases.Aug 23, 2016

Cannabinoids inhibit glioma (brain cancer) through the down-regulation of Tissue Inhibitors of Metalloproteinases (TIMPs). Jan 01, 2008

Cannabis has been reported to have therapeutic properties in the prevention of cluster headache attacks.Jun 01, 2009

Cannabis use is not uncommon in ALS patients who reported significant benefits from its use.Mar 01, 2004

Cannabis-assisted psychotherapy for complex dissociative posttraumatic stress disorder.Dec 31, 2022

Cutaneous squamous cell carcinoma and Lichen simplex chronicus successfully treated with topical cannabinoid oil.Mar 31, 2022

Effectiveness of highly purified cannabidiol in refractory and super-refractory status epilepticus.Jun 20, 2024

Four patients treated with CBD had prompt and substantial reduction in the frequency of REM sleep behaviour disorder related events without side effects.Sep 30, 2014

Further research may be appropriate to elucidate the increasingly recognized effect of cannabis/cannabinoids on gliomas.Mar 31, 2011

Medical cannabis activity against inflammation: active compounds and modes of action.Dec 31, 2021

Potential role of cannabidiol for seizure control in a patient with recurrent glioma.Dec 13, 2019

Successful use of pure cannabidiol for the treatment of super-refractory status epilepticus.Dec 31, 2017

THC combined with CBD led to a rapid and highly significant improvement in a patient with Tourette syndrome. Jul 29, 2018

The data presented here may indicate that CBD led to a partial tumour response in a patient with histologically proven adenocarcinoma of the lung.Dec 31, 2018

The subject in this study is nearly one year using only natural product cannabis plus supplements for his severe pain. May 17, 2009

These cases support pre-clinical and preliminary clinical evidence suggesting that CBD may be effective for some patients with epilepsy. Dec 31, 2015

Traditional Chinese medicine hemp seed pill could improve chronic constipation of elderly.May 31, 2019

CBD exhibits anti-seizure properties in acute seizure models.May 05, 2017

Insights on cannabidiol's antiallodynic and anxiolytic mechanisms of action in a model of neuropathic pain.Aug 31, 2019

Vasorelaxant effect of Moroccan Cannabis sativa threshing residues on rat mesenteric arterial bed is endothelium and muscarinic receptors dependent.Dec 31, 2022

Δ9-Tetrahydrocannabinolic Acid markedly alleviates liver fibrosis and inflammation.Nov 29, 2020

A cannabigerol enriched cannabis extract could be used as an appetite stimulant.Jan 24, 2017

A cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis.Aug 07, 2006

A cannabinoid type 1 receptor antagonist improves sodium balance and delays decompensation in preascitic cirrhosis. Jul 01, 2009

A cannabis extract with high content in cannabidiol attenuated chemically-induced intestinal inflammation.Dec 31, 2015

A chronic low dose of Δ9-tetrahydrocannabinol (THC) restores cognitive function in old mice.May 07, 2017

A combination of Cannabichromene and Delta-tetrahydrocannabinol leads to enhanced tetrad and anti-inflammatory actions.Oct 31, 2010

A hemp seed meal protein hydrolysate contained antioxidant peptides that reduced the rate of lipid peroxidation in spontaneously hypertensive rats.Nov 30, 2014

A hemp seed meal protein hydrolysate had strong hypotensive effects in spontaneously hypertensive rats.Jul 31, 2014

A nanoformulation of THC revealed a statistically significant selective cytotoxic effect towards lung cancer cell lines.Jun 19, 2015

A single ultra-low dose of THC before ischemia is a safe and effective treatment that reduces myocardial ischemic damage.May 31, 2013

A synthetic cannabinoid inhibited CXCL12-induced migration and invasive properties of breast cancer cells.Dec 31, 2010

Abnormal cannabidiol ameliorates inflammation preserving pancreatic beta cells.Dec 31, 2021

Activation of cannabinoid receptors could be a new therapeutic approach for the treatment of skin tumors.Dec 31, 2002

Activation of cannabinoid system may have protective actions on both liver and brain induced by cocaine, minimizing inflammatory injury promoted by cocaine.Dec 31, 2014

Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion.Jul 01, 2010

Administration of synthetic 2-AG to mice after CHI led to significant reduction of brain oedema, better clinical recovery, reduced infarct volume and reduced hippocampal cell death compared with controls.Oct 03, 2001

Administration of THC was observed to enhance the neurogenesis in the brainSep 20, 2017

Adolescent exposure to chronic delta-9-tetrahydrocannabinol blocks opiate dependence in maternally deprived rats.Sep 30, 2009

Ameliorative effects of hempseed against hypercholesterolemia associated cardiovascular changes.Sep 12, 2019

Amphirregulin is a factor for resistance of glioma cells to THC-induced apoptosis.Sep 30, 2009

An extract of fructus cannabis ameliorates learning and memory impairment induced by d-galactose.Dec 31, 2016

Analgesic and anti-inflammatory effects of 1% topical cannabidiol gel in animal models.Sep 04, 2023

Anti-fatigue activity of hemp leaves water extract and the related biochemical changes.Mar 31, 2021

Anti-inflammatory effects of cannabidiol in early stages of neuroinflammation induced by high-fat diet.Feb 29, 2024

Antiapoptotic effects of cannabidiol in an experimental model of cognitive decline induced by brain iron overload.Sep 02, 2018

Anticonvulsant and neuroprotective effects of cannabidiol during the juvenile period.Aug 27, 2018

Anticonvulsive properties of cannabidiol in a model of generalized seizure are transient receptor potential vanilloid 1 dependent.May 31, 2020

Antidepressant-like effect induced by cannabidiol is dependent on brain serotonin levels.Jun 05, 2018

Antinociceptive action of cannabidiol on thermal sensitivity and post-operative pain.Feb 28, 2024

Antinociceptive and anti-inflammatory properties of cannabidiol alone and in combination with standardized bioflavonoid composition.Feb 09, 2021

Antitumor effects of cannabinoids in human pancreatic ductal adenocarcinoma cell line.Dec 31, 2021

Avidekel cannabis extracts and cannabidiol are as efficient as copaxone in suppressing experimental autoimmune encephalomyelitis in mice.Oct 04, 2018

Broad-spectrum cannabis oil ameliorates reserpine-induced fibromyalgia model in mice.Sep 30, 2022

Cannabichromene could be considered for clinical experimentation in inflammatory bowel disease patients.Apr 30, 2013

Cannabichromene raises the viability of NSPCs while inhibiting their differentiation into astroglia.Oct 31, 2013

Cannabichromene selectively reduces inflammation-induced hypermotility in vivo.May 31, 2012

Cannabidiol acts in the dorsal striatum to improve haloperidol-induced catalepsy.Apr 26, 2016

Cannabidiol administration after hypoxia-ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function.Sep 30, 2012

Cannabidiol alleviates carbon tetrachloride-induced liver fibrosis.Dec 31, 2023

Cannabidiol alleviates neurological deficits after traumatic brain injury.Apr 28, 2024

Cannabidiol alleviates oral mucositis.Jul 04, 2024

Cannabidiol alleviates right ventricular fibrosis by inhibiting the transforming growth factor β pathway.Jul 31, 2023

Cannabidiol ameliorates cognitive function via regulation of IL-33 and TREM2 upregulation.Feb 16, 2021

Cannabidiol ameliorates inflammatory response partly by AGE-RAGE pathway in diabetic mice.Oct 31, 2023

Cannabidiol ameliorates monocrotaline-induced pulmonary hypertension in rats. Sep 24, 2020

Cannabidiol ameliorates PTSD-like symptoms by inhibiting neuroinflammation.May 14, 2024

Cannabidiol ameliorates the anxiogenic and compulsive-like behaviors induced by chronic consumption of a high-carbohydrate diet.Aug 29, 2022

Cannabidiol and abnormal cannabidiol reduced the infarct volume. Apr 30, 2005

Cannabidiol and beta-caryophyllene in combination: A therapeutic functional interaction.Dec 06, 2022

Cannabidiol and cannabigerol, non-psychotropic cannabinoids, as analgesics that effectively manage bone fracture pain and promote healing.Aug 18, 2023

Cannabis

View the Evidence:
1192 Abstracts with Cannabis Research