Carnosol

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54 Diseases Researched for Carnosol
NameACCKFocus
Inflammation810Locked
Breast Cancer57Locked
Ischemia35Locked
Osteoarthritis15Locked
Breast Cancer: Triple Negative 34Locked
Cancers: All44Locked
Colitis24Locked
Oxidative Stress34Locked
Sepsis24Locked
Skin Cancer34Locked
Atopic Dermatitis23Locked
Colon Cancer33Locked
Osteoporosis13Locked
Prostate Cancer33Locked
Aging12Locked
Brain: Oxidative Stress12Locked
Cachexia: Cancer22Locked
DNA damage12Locked
Diabetes: Oxidative Stress12Locked
Diabetic Complications12Locked
Fibrosarcoma12Locked
Gastric Cancer12Locked
Glioblastoma22Locked
Inflammatory Bowel Diseases12Locked
Intestinal Ischemia12Locked
Kidney Damage12Locked
Lipopolysaccharide-Induced Toxicity22Locked
Melanoma22Locked
Neurodegenerative Diseases12Locked
Radiation Induced Illness22Locked
Spinal Cord Injuries12Locked
Ultraviolet Radiation Induced Damage22Locked
Acute T cell Leukemias11Locked
Alzheimer's Disease11Locked
Autoimmune Diseases11Locked
Brain Inflammation 11Locked
Depression11Locked
Diabetes Mellitus: Type 211Locked
Encephalomyelitis11Locked
Endotoxemia11Locked
Liver Cancer11Locked
Liver Fibrosis11Locked
Lymphoma11Locked
Multiple Sclerosis11Locked
Muscle Atrophy 11Locked
Nonalcoholic fatty liver disease (NAFLD)11Locked
Osteosarcoma11Locked
Ovarian Cancer11Locked
Parkinson's Disease11Locked
Prion Diseases11Locked
Radiation-Induced Illness: Cesium-137 Exposure11Locked
Respiratory Diseases11Locked
Staphylococcus aureus infection11Locked
Stroke: Ischemic11Locked
48 Pharmacological Actions Researched for Carnosol
NameACCKFocus
Anti-Inflammatory Agents1727Locked
Antioxidants1522Locked
Antiproliferative 1113Locked
Apoptotic1011Locked
Interleukin-6 Downregulation511Locked
NF-kappaB Inhibitor611Locked
Neuroprotective Agents57Locked
Antineoplastic Agents56Locked
Nrf2 activation36Locked
Cyclooxygenase 2 Inhibitors35Locked
Anticarcinogenic Agents24Locked
Gastrointestinal Agents24Locked
Gastroprotective24Locked
Superoxide Dismutase Up-regulation24Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor34Locked
Cell cycle arrest23Locked
Hypoglycemic Agents23Locked
Immunomodulatory23Locked
Interleukin-1 beta downregulation23Locked
STAT3 Inhibitor23Locked
Anti-Angiogenic12Locked
Anti-Apoptotic12Locked
Anti-Bacterial Agents22Locked
Anti-Cachexic Agents22Locked
Anti-metastatic12Locked
Antinoceceptive 12Locked
Chemopreventive22Locked
Chemotherapeutic22Locked
Malondialdehyde Down-regulation12Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor12Locked
Prophylactic Agents12Locked
Radioprotective22Locked
Renoprotective12Locked
Tumor Suppressor Protein p53 Upregulation22Locked
Analgesics11Locked
Anti-Fibrotic11Locked
Anti-Infective Agents11Locked
Antimutagenic Agents11Locked
Autophagy Up-regulation11Locked
Cardioprotective11Locked
Chemosensitizer11Locked
Immunomodulatory: Th17 downregulation11Locked
Interleukin-10 upregulation11Locked
Interleukin-4 downregulation11Locked
Interleukin-4 upregulation11Locked
Interleukin-5 downregulation11Locked
Quorum Sensing Inhibition11Locked
interleukin-13 down-regulation11Locked

View the Evidence:
55 Abstracts with Carnosol Research

[+]

Carnosol inhibits pro-inflammatory and catabolic mediators of cartilage breakdown in human osteoarthritic chondrocytes.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(8):e0136118. Epub 2015 Aug 20. PMID: 26292290
Article Published Date : Dec 31, 2014
Study Type : Human In Vitro
Additional Links
Substances : Carnosol
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation
[+]

Carnosol alleviates sepsis-induced pulmonary endothelial barrier dysfunction.Feb 26, 2024

Pubmed Data : Phytother Res. 2024 Feb 27. Epub 2024 Feb 27. PMID: 38414287
Article Published Date : Feb 26, 2024
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Sepsis
Pharmacological Actions : Antioxidants, Nrf2 activation
[+]

Carnosol inhibits osteoclastogenesis in vivo and in vitro.Jun 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2022 Jul ;26(1). Epub 2022 May 20. PMID: 35593299
Article Published Date : Jun 30, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Carnosol and carnosic acid displayed significant and dose-dependent anti-inflammatory and anti-nociceptive effects.Jul 26, 2016

Pubmed Data : Br J Pharmacol. 2016 Jul 27. Epub 2016 Jul 27. PMID: 27464306
Article Published Date : Jul 26, 2016
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid, Carnosol
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antinoceceptive
Additional Keywords : Dose Response
[+]

Carnosol could be explored as a potential dietary supplement to slow aging.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2019 ;2019:5958043. Epub 2019 Jun 24. PMID: 31341531
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Carnosol
Diseases : Aging
Pharmacological Actions : Antioxidants
[+]

Carnosol maintains i ntestinal barrier function and mucosal immune homeostasis in DSS-induced colitis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2022 ;9:894307. Epub 2022 May 24. PMID: 35685885
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Carnosol
Diseases : Colitis
Pharmacological Actions : Gastrointestinal Agents, Gastroprotective
[+]

Carnosol may represent a promising therapeutic candidate that canmodulate breast cancer growth and metastasis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Oncol. 2019 ;9:743. Epub 2019 Aug 8. PMID: 31456939
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Carnosol
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Carnosol pretreatment attenuates liver injury induced by intestinal ischemia reperfusion.Jul 13, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2009 Jul 14 ;15(26):3240-5. PMID: 19598299
Article Published Date : Jul 13, 2009
Study Type : Animal Study
Additional Links
Substances : Carnosol
Diseases : Intestinal Ischemia
Pharmacological Actions : Interleukin-6 Downregulation, NF-kappaB Inhibitor, Superoxide Dismutase Up-regulation
[+]

Carnosol protects against renal ischemia-reperfusion injury in rats.Oct 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Anim. 2018 Nov 1 ;67(4):545-553. Epub 2018 Jul 31. PMID: 30068825
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Substances : Carnosol
Diseases : Ischemia, Kidney Damage
Pharmacological Actions : Anti-Apoptotic, Renoprotective
[+]

Carnosol protects against spinal cord injury through Nrf-2 upregulation.Dec 31, 2015

Pubmed Data : J Recept Signal Transduct Res. 2016 ;36(1):72-8. Epub 2015 Jul 6. PMID: 26791582
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Carnosol
Diseases : Oxidative Stress, Spinal Cord Injuries
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Nrf2 activation
[+]

Carnosol suppresses patient-derived gastric tumor growth by targeting RSK2.Sep 27, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2018 Sep 28 ;9(76):34200-34212. Epub 2018 Feb 6. PMID: 30344937
Article Published Date : Sep 27, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Gastric Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Evaluation of anti-cancer and immunomodulatory effects of carnosol in a Balb/c WEHI-164 fibrosarcoma model.Jun 30, 2015

Pubmed Data : J Immunotoxicol. 2015 Jul-Sep;12(3):231-8. Epub 2014 Jul 16. PMID: 25027673
Article Published Date : Jun 30, 2015
Study Type : Animal Study
Additional Links
Substances : Carnosol
Diseases : Fibrosarcoma
Pharmacological Actions : Antineoplastic Agents, Immunomodulatory
[+]

Inhibitory effect of carnosol on phthalic anhydride-induced atopic dermatitis via inhibition of STAT3.Aug 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomol Ther (Seoul). 2017 Sep 1 ;25(5):535-544. PMID: 28655070
Article Published Date : Aug 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Atopic Dermatitis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, STAT3 Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effect of carnosol on lung injury induced by intestinal ischemia/reperfusion.Aug 31, 2010

Pubmed Data : Surg Today. 2010 Sep ;40(9):858-65. Epub 2010 Aug 26. PMID: 20740350
Article Published Date : Aug 31, 2010
Study Type : Animal Study
Additional Links
Substances : Carnosol
Diseases : Ischemia
Pharmacological Actions : Interleukin-6 Downregulation, NF-kappaB Inhibitor, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

Protective effects of carnosol against oxidative stress induced brain damage by chronic stress in rats.May 03, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 May 4 ;17(1):249. Epub 2017 May 4. PMID: 28472953
Article Published Date : May 03, 2017
Study Type : Animal Study
Additional Links
Substances : Carnosol
Diseases : Brain: Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents
Additional Keywords : Natural Substances Versus Drugs, Plant Extracts
[+]

Rosemary and carnosol inhibit chemically-induced rat mammary tumorigenesis and DNA adduct formation. Jun 24, 1996

Pubmed Data : Cancer Lett. 1996 Jun 24;104(1):43-8. PMID: 8640744
Article Published Date : Jun 24, 1996
Study Type : Animal Study
Additional Links
Substances : Carnosol, Rosemary
Diseases : Breast Cancer, DNA damage
Pharmacological Actions : Anticarcinogenic Agents
[+]

Rosemary and its constituents carnosol and ursolic acid inhibit skin cancer formation. Feb 01, 1994

Pubmed Data : Cancer Res. 1994 Feb 1;54(3):701-8. PMID: 8306331
Article Published Date : Feb 01, 1994
Study Type : Animal Study
Additional Links
Substances : Carnosol, Rosemary, Ursolic Acid
Diseases : Skin Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antioxidants
Additional Keywords : Plant Extracts
[+]

Rosemary extract can be an effective preventative agent against inflammatory bowel disease.Feb 26, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Feb 27 ;13(3). Epub 2021 Feb 27. PMID: 33673488
Article Published Date : Feb 26, 2021
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid, Carnosol, Rosemary
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Gastrointestinal Agents, Gastroprotective, Prophylactic Agents
[+]

The present investigation proposes that carnosol may improve diabetes and its complications.Jul 03, 2017

Pubmed Data : Cardiovasc Hematol Disord Drug Targets. 2017 Jul 4 ;17(1):11-17. PMID: 28034282
Article Published Date : Jul 03, 2017
Study Type : Animal Study
Additional Links
Substances : Carnosol
Diseases : Diabetes: Oxidative Stress, Diabetic Complications, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hypoglycemic Agents
[+]

These results suggest that carnosic acid and rosemary extract can be useful in the prevention of disorders due to angiogenesis.Dec 31, 2011

Pubmed Data : Biosci Biotechnol Biochem. 2012 ;76(1):115-9. Epub 2012 Jan 7. PMID: 22232247
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid, Carnosol, Rosemary
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Anti-Angiogenic, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

A review of the dietary components carnosic acid and carnosol as neuroprotective agents.Oct 31, 2016

Pubmed Data : Mol Neurobiol. 2016 Nov ;53(9):6155-6168. Epub 2015 Nov 9. PMID: 26553346
Article Published Date : Oct 31, 2016
Study Type : Review
Additional Links
Substances : Carnosic Acid, Carnosol
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Antitumor activity of the dietary diterpene carnosol against a panel of human cancer cell lines.May 31, 2014

Pubmed Data : Food Funct. 2014 Jun ;5(6):1261-9. Epub 2014 Apr 15. PMID: 24733049
Article Published Date : May 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Breast Cancer: Triple Negative , Cancers: All, Ovarian Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative
[+]

Carnosic acid carnosol exert a protective effect against diabetes and fatty liver disease, as well as subsequent cases of hepatoma.Apr 13, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2021 Apr 14 ;22(8). Epub 2021 Apr 14. PMID: 33919842
Article Published Date : Apr 13, 2021
Study Type : In Vitro Study
Additional Links
Substances : Carnosic Acid, Carnosol
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Gene Expression Regulation
[+]

Carnosic acid and carnosol display antioxidant and anti-prion properties.Apr 05, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2022 Apr 6 ;11(4). Epub 2022 Apr 6. PMID: 35453411
Article Published Date : Apr 05, 2022
Study Type : In Vitro Study
Additional Links
Substances : Carnosic Acid, Carnosol
Diseases : Prion Diseases
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Carnosol activates Nrf2 leading to sestrin 2 induction in colon cells.Jul 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Mol Med. 2018 Aug ;5(4). Epub 2018 Aug 15. PMID: 30972223
Article Published Date : Jul 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Colon Cancer
Pharmacological Actions : Antioxidants, Nrf2 activation
[+]

Carnosol ameliorated cancer cachexia-associated myotube atrophy.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2023 ;14:1291194. Epub 2024 Jan 5. PMID: 38249348
Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Cachexia: Cancer
Pharmacological Actions : Anti-Cachexic Agents
[+]

Carnosol and carnosic acid exhibit antioxidant and antiproliferative activities in a concentration-dependent manner.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:7623830. Epub 2019 Nov 16. PMID: 31827560
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Carnosic Acid, Carnosol, Rosemary
Diseases : Oxidative Stress
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Pharmacological Actions : Antioxidants, Antiproliferative
[+]

Carnosol and its analogues attenuate muscle atrophy and fat lipolysis induced by cancer cachexia.May 04, 2021

Pubmed Data : J Cachexia Sarcopenia Muscle. 2021 May 5. Epub 2021 May 5. PMID: 33951335
Article Published Date : May 04, 2021
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Cachexia: Cancer, Muscle Atrophy
Pharmacological Actions : Anti-Cachexic Agents, Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Carnosol attenuates LPS-induced inflammation of cardiomyoblasts by inhibiting NF- κB.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:7969422. Epub 2022 May 4. PMID: 35571740
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective
[+]

Carnosol controls the human glioblastoma stemness features.Nov 08, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Nov 9 ;7(1):15174. Epub 2017 Nov 9. PMID: 29123181
Article Published Date : Nov 08, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Glioblastoma
Pharmacological Actions : Apoptotic, Chemotherapeutic
Additional Keywords : Cancer Stem Cells, Natural Substance/Drug Synergy
[+]

Carnosol has enormous potential for development as a therapeutic agent for autoimmune diseases such as multiple sclerosis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2018 ;9:1807. Epub 2018 Aug 13. PMID: 30150982
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Autoimmune Diseases, Encephalomyelitis, Multiple Sclerosis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Carnosol has potential as a glucose homeostasis regulating agent.Apr 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 Apr 29 ;19(5). Epub 2018 Apr 29. PMID: 29710819
Article Published Date : Apr 28, 2018
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
[+]

Carnosol has protective effects on skin inflammatory skin damages by UVB.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Pharm Res. 2019 Mar ;42(3):274-283. Epub 2018 Nov 15. PMID: 30430364
Article Published Date : Feb 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Inflammation, Ultraviolet Radiation Induced Damage
Therapeutic Actions : Sunlight exposure
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors
[+]

Carnosol induces apoptosis in adult T-cell leukemia/lymphoma cells.Mar 31, 2014

Pubmed Data : Hum Cell. 2014 Apr ;27(2):68-77. Epub 2013 Dec 10. PMID: 24323765
Article Published Date : Mar 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Acute T cell Leukemias, Lymphoma
Pharmacological Actions : Apoptotic
Additional Keywords : Phytotherapy
[+]

Carnosol induces apoptosis in human colon cancer HCT116 cells.Mar 31, 2014

Pubmed Data : Int J Oncol. 2014 Apr ;44(4):1309-15. Epub 2014 Jan 27. PMID: 24481553
Article Published Date : Mar 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Colon Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, STAT3 Inhibitor, Tumor Suppressor Protein p53 Upregulation
[+]

Carnosol induces p38-mediated ER stress response and autophagy in human breast cancer cells.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Oncol. 2022 ;12:911615. Epub 2022 May 31. PMID: 35712465
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Breast Cancer
Pharmacological Actions : Apoptotic
[+]

Carnosol induces ROS-mediated beclin1-independent autophagy and apoptosis in triple negative breast cancer.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(10):e109630. Epub 2014 Oct 9. PMID: 25299698
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Antioxidants, Antiproliferative , Apoptotic, Autophagy Up-regulation
[+]

Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseasesApr 19, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Death Dis. 2020 Apr 20 ;11(4):252. Epub 2020 Apr 20. PMID: 32312957
Article Published Date : Apr 19, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Endotoxemia, Inflammation, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Carnosol is a novel inhibitor of p300 acetyltransferase in breast cancer.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Oncol. 2021 ;11:664403. Epub 2021 May 13. PMID: 34055630
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Breast Cancer
Pharmacological Actions : Chemotherapeutic
[+]

Carnosol led to p53 reactivation in the U87MG human glioblastoma cell line.Apr 30, 2016

Pubmed Data : Int J Biochem Cell Biol. 2016 May ;74:95-108. Epub 2016 Mar 3. PMID: 26939786
Article Published Date : Apr 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Glioblastoma
Pharmacological Actions : Antineoplastic Agents, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Chemotherapeutic Synergy: Temozolomide, Reactivation Of Tumor Suppressor Gene
[+]

Carnosol may be developed as a radioprotective agent in the non-tumoral cells. Aug 31, 2013

Pubmed Data : Clin Transl Oncol. 2013 Sep ;15(9):712-9. Epub 2013 Jan 29. PMID: 23359182
Article Published Date : Aug 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Melanoma, Radiation Induced Illness, Skin Cancer
Pharmacological Actions : Antioxidants, Radioprotective
[+]

Carnosol may be effective as an anti-tumor agent in the different types of cancer by inducing apoptosis and inhibiting the cell cycle division.Dec 31, 2017

Pubmed Data : Curr Drug Discov Technol. 2018 ;15(1):32-40. PMID: 28412913
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Carnosol
Diseases : Cancers: All
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Carnosol may represent an attractive candidate for anti-fibrotic clinical therapy.Jan 31, 2018

Pubmed Data : Pharmacol Res. 2018 Feb ;128:327-337. Epub 2017 Oct 26. PMID: 29106960
Article Published Date : Jan 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic
[+]

Carnosol might be a potential treatment for hormone-independent prostate cancer.Aug 29, 2017

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2017 Aug 30 ;63(8):104-108. Epub 2017 Aug 30. PMID: 28886322
Article Published Date : Aug 29, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Prostate Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Carnosol might serve as a potential therapeutic agent against osteosarcoma.Dec 31, 2016

Pubmed Data : Am J Chin Med. 2017 ;45(8):1761-1772. Epub 2017 Nov 9. PMID: 29121803
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Osteosarcoma
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Apoptotic
[+]

Carnosol suppresses microglia cell inflammation and apoptosis through PI3K/AKT/mTOR signaling pathway.May 05, 2022

Pubmed Data : Immunopharmacol Immunotoxicol. 2022 May 6:1-11. Epub 2022 May 6. PMID: 35521965
Article Published Date : May 05, 2022
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Inflammation, Stroke: Ischemic
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Carnosol treatment could be a new strategy for protecting lungs from ischemia-reperfusion injury by modulating the ATF3-IL-6 axis.Jan 11, 2018

Pubmed Data : Biochem Cell Biol. 2018 12 ;96(6):769-776. Epub 2018 Jun 29. PMID: 29958095
Article Published Date : Jan 11, 2018
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Ischemia, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Interleukin-6 Downregulation
[+]

Carnosol: a promising anti-cancer and anti-inflammatory agent.May 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Lett. 2011 Jun 1 ;305(1):1-7. Epub 2011 Mar 5. PMID: 21382660
Article Published Date : May 31, 2011
Study Type : Review
Additional Links
Substances : Carnosol
Diseases : Breast Cancer, Cancers: All, Colon Cancer, Inflammation, Prostate Cancer, Skin Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Antineoplastic Agents, Antioxidants
[+]

Effects of rosmarinic acid, carnosic acid, rosmanol, carnosol, and ursolic acid on the pathogenesis of respiratory diseases.Dec 22, 2022

Pubmed Data : Biofactors. 2022 Dec 23. Epub 2022 Dec 23. PMID: 36564953
Article Published Date : Dec 22, 2022
Study Type : In Vitro Study
Additional Links
Substances : Carnosic Acid, Carnosol, Rosmarinic acid, Ursolic Acid
Diseases : Respiratory Diseases
Pharmacological Actions : Anti-Inflammatory Agents, interleukin-13 down-regulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

Fat soluble antioxidants protect against radiation toxicity. Nov 01, 2003

Pubmed Data : Anticancer Res. 2003 Nov-Dec;23(6C):4693-701. PMID: 19188244
Article Published Date : Nov 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Antioxidants: Fat Soluble, Carnosol, Carsonic Acid, Flavonoids, Vitamin E
Diseases : Radiation Induced Illness, Radiation-Induced Illness: Cesium-137 Exposure
Pharmacological Actions : Antimutagenic Agents, Antioxidants, Radioprotective
[+]

Polyphenols from the Mediterranean herb rosemary for prostate cancer.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2013 ;4:29. Epub 2013 Mar 25. PMID: 23531917
Article Published Date : Dec 31, 2012
Study Type : Review
Additional Links
Substances : Carnosic Acid, Carnosol, Rosemary
Diseases : Prostate Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest
[+]

Rosmarinus officinalis L.: an update review of its phytochemistry and biological activity.Mar 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Future Sci OA. 2018 Apr ;4(4):FSO283. Epub 2018 Feb 1. PMID: 29682318
Article Published Date : Mar 31, 2018
Study Type : Review
Additional Links
Substances : Carnosic Acid, Carnosol, Rosemary, Rosmarinic acid
Diseases : Alzheimer's Disease, Depression, Inflammation, Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Analgesics, Anti-Bacterial Agents, Anti-Infective Agents, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Specific inhibition of S. aureus virulence using topical formulations of rosemary extract may offer a practical approach to preventing and treating flares of atopic dermatitis.Mar 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antibiotics (Basel). 2020 Mar 31 ;9(4). Epub 2020 Mar 31. PMID: 32244277
Article Published Date : Mar 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Carnosic Acid, Carnosol, Rosemary
Diseases : Atopic Dermatitis, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents, Quorum Sensing Inhibition
[+]

The purpose of this review is to shed light on the detailed mechanistic aspects of cancer chemoprevention with carnosol.May 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cancer Prev. 2014 Jun ;19(2):103-10. PMID: 25337578
Article Published Date : May 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Cancers: All
Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative , Apoptotic, Chemopreventive, Chemosensitizer
[+]

These results indicate the role of carnosol as a potential chemopreventive agent upon UVB radiation.Feb 22, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2018 Feb 23 ;8(1):3574. Epub 2018 Feb 23. PMID: 29476131
Article Published Date : Feb 22, 2018
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Melanoma, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Chemopreventive, NF-kappaB Inhibitor

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