Carotenoids

Name	AC	CK
Oxidative Stress	80	248
Macular Degeneration	16	148
Breast Cancer	16	124
Cognitive Decline/Dysfunction	12	92
Cataract	13	84
Breast Cancer: Prevention	5	82
Cardiovascular Diseases	15	77
Inflammation	19	76
DNA damage	15	72
Gastric Cancer	5	52
Lipid Peroxidation	17	47
Radiation Induced Illness	5	47
Lung Cancer	8	45
Alzheimer's Disease	15	41
Aging: Brain	2	40
Endometrial Cancer	3	40
Prostate Cancer	11	40
Prostate Cancer: Prevention	1	40
Memory Disorders	6	38
Obesity	10	36
Diabetes Mellitus: Type 2	9	35
Athletic Performance	5	34
C-Reactive Protein	4	32
Overweight	4	32
Pancreatic Cancer	3	32
Coronary Artery Disease	3	31
Smoking	4	31
Cystic Fibrosis	3	30
Vision Disorders	2	30
Vision Loss	2	30
Ultraviolet Radiation Induced Damage	11	29
Cancers: All	18	28
Colon Cancer	10	28
Eye Diseases	4	26
Immune Disorders: Low Immune Function	4	25
Vitamin A Deficiency	3	24
Human Papillomavirus (HPV)	4	23
Stroke	2	23
High Homocysteine	3	22
Muscle Damage: Exercise-Induced	3	22
Aging Skin	3	21
Alcohol Toxicity	7	21
Dementia	2	21
Diabetic Complications	10	21
Hypertension	7	21
All-Cause Mortality	1	20
Bladder Cancer: Prevention	1	20
Bone Fractures	1	20
Cancer Mortality	1	20
Cardiac Mortality	1	20
Gastric Cancer: Prevention	1	20
Helicobacter Pylori Infection	8	20
Hypercholesterolemia	1	20
Metabolic Diseases	1	20
Retinoblastoma	1	20
Visual Display Terminal Eye Fatigue	1	20
Diabetes Mellitus: Type 1	4	19
Insulin Resistance	6	19
Liver Cancer: Prevention	4	19
Depression	5	18
Liver Cancer	12	18
Nonalcoholic fatty liver disease (NAFLD)	5	17
Lung Cancer: Prevention	2	16
Metabolic Syndrome X	4	16
Sunburn	3	16
Cervical Cancer	5	15
Atherosclerosis	7	14
Periodontitis	3	14
Sleep Disorders	2	14
Glaucoma	2	13
Brain Inflammation	7	12
High Fat Diet	6	12
Infertility: Male	2	12
Retinal Diseases	2	12
Uterine Cervical Neoplasms	2	12
Acid Reflux	2	11
Cancers: Multi-Drug Resistant	6	11
Cerebral Ischemia	6	11
AST: Elevated	1	10
Apolipoprotein A/B ratio imbalances	1	10
Bladder Cancer	1	10
Cervical Dysplasia	1	10
Chemotherapy and Radiation Toxicity	4	10
Cholesterol: LDL/HDL ratio	1	10
Clostridium Infections	1	10
Colon Cancer: Prevention	1	10
Common variable immunodeficiency (CVID)	1	10
Computer display light exposure	1	10
Creatine Phosphokinase (CK): Elevated	1	10
Diabetes Insipidus	1	10
Diabetes Mellitus: Type 2: Prevention	1	10
Diabetes: Oxidative Stress	5	10
Diabetic Retinopathy	5	10
Eye Diseases: Lack of Blood Circuation	1	10
Fatty Liver	6	10
Hearing Loss	1	10
Infant Nutrition	1	10
Kidney Cancer	1	10
Leukoplakia	1	10
Lipopolysaccharide-Induced Toxicity	6	10
Low Testosterone	1	10
Male Hormone Imbalances	1	10
Menopausal Syndrome	1	10
Mental Fatigue	1	10
Neurodegenerative Diseases	9	10
Osteoporosis	1	10
Periodontal Wound Healing	1	10
Pneumonia	1	10
Rheumatoid Arthritis	1	10
Testosterone: Too Low	1	10
Thyroid Cancer	1	10
Visual Fatigue	1	10
Diabetic Nephropathy	4	8
Liver Fibrosis	5	8
Spinal Cord Injuries	4	8
Aging	4	7
Colorectal Cancer	5	7
Oral Cancer	3	7
Photooxidative Stress	4	7
Alcoholic Liver Disease	3	6
Atopic Dermatitis	3	6
Brain Injury: Traumatic	3	6
Cardiac Hypertrophy	2	6
Chemotherapy-Induced Toxicity: Cisplatin	3	6
Gastric Ulcer	3	6
Kidney Damage	3	6
Kidney Fibrosis	3	6
Retinitis Pigmentosa	2	6
Skin Cancer: Prevention	1	6
Subarachnoid hemorrhage	3	6
Xenobiotic Exposures	2	6
Advanced Glycation Endproduct (AGE) Formation	1	5
Asthma	4	5
Endothelial Dysfunction	3	5
Esophageal Cancer	5	5
Glioblastoma	1	5
Hypoxia	3	5
Myocardial Fibrosis	1	5
Neutrophils: Damaged	1	5
Oral Lichen Planus	1	5
Parkinson's Disease	4	5
Wound Healing	3	5
Acetaminophen (Tylenol) Toxicity	2	4
Autoimmune Diseases	1	4
Burns	2	4
Cancer Metastasis	3	4
Chemically-Induced Liver Damage	2	4
Chemotherapy-Induced Toxicity: Cyclophosphamide	2	4
Cholesterol: Oxidation	2	4
Colitis	2	4
Delayed Sleep Phase Disorder	1	4
Diabetes: Cardiovascular Illness	2	4
Dyslipidemias	2	4
Eye Damage	2	4
Fructose-Induced Toxicity	2	4
High Fructose Diet	2	4
Hyperglycemia	2	4
Insomnia	1	4
Leukemia	2	4
Liver Damage: Drug-Induced	2	4
Liver Injury: Ischemia/reperfusion	2	4
Low Immune Function: Splenic Dysfunction	1	4
Lung Injury: Acute	2	4
Lymphadenopathy	1	4
Lymphoma	1	4
Maculopathy: Age-Related	1	4
Middle Cerebral Artery Occlusion (MCAO)	2	4
Mitochondrial Dysfunction	3	4
Muscle Atrophy	2	4
Photokeratitis	2	4
Proteinuria	1	4
Retinal Degeneration: Light-Induced	2	4
Skin Cancer	1	4
Squamous cell carcinoma	1	4
Stress	2	4
Stroke: Prevention	2	4
Tongue Cancer	1	4
Tracheal Cancer	1	4
Cancers: Drug Resistant	2	3
Carcinoma: Non-Small-Cell Lung	3	3
Diabetes: Cognitive Dysfunction	2	3
Drug Toxicity: Methotrexate	2	3
Fibrosis	2	3
Hydrogen Peroxide Induced Toxicity	3	3
Iron Overload	1	3
Iron Poisoning	1	3
Liver Damage	2	3
Myocardial Ischemia	2	3
Osteoarthritis	2	3
Skin Diseases: Photo-Aging	2	3
Agent Orange Toxicity	1	2
Allergic Airway Diseases	1	2
Aluminum Toxicity	1	2
Arsenic Poisoning	1	2
Arterial Hardening: Elasticity	1	2
Arthritis	1	2
Aspirin-Induced Toxicity	1	2
Bladder Outlet Obstruction	1	2
Blindness	1	2
Blood Pressure: High	1	2
Blue Light Toxicity	1	2
Brain Ischemia	1	2
Brain: Oxidative Stress	1	2
Breast Cancer: Chemically-Induced	1	2
Breast Cancer: Triple Negative	1	2
Cachexia	1	2
Cancer Stem Cells	2	2
Cardiomegaly	1	2
Chemotherapy-Induced Toxicity: Doxorubicin	1	2
Chemotherapy-Induced Toxicity: Gentamicin	1	2
Chemotherapy-Induced Toxicity: Kidney	1	2
Coenzyme Q10 Deficiency	1	2
Cough	1	2
Dental Caries	1	2
Dental Diseases	1	2
Diabetes: Dental Problems	1	2
Diabetes: Immune Problems	1	2
Diabetes: Low Immune Function	1	2
Drug-Induced Toxicity: Indomethacin	1	2
Drug-Induced Toxicity: Methotrexate	1	2
Epilepsy	1	2
Erythema	1	2
Exercise-Induced Tissue Damage	1	2
Fibrosarcoma	1	2
Gastrointestinal Inflammation	1	2
Hepatic Steatosis	1	2
High Cholesterol	1	2
High Sugar Diet	1	2
Homocysteine: Elevated	1	2
Hyperhomocysteinemia	1	2
Immune Dysregulation: TH1 dominance	1	2
Infertility: Female	1	2
Intestinal Injury	1	2
Intima Media Thickening	1	2
Intraocular hypertension	1	2
Ischemia	1	2
Kidney Damage: Drug-Induced	1	2
Kidney Diseases	1	2
Learning disorders	1	2
Liver Cirrhosis	1	2
Low Libido	1	2
Mastocytoma	1	2
Memory Loss	1	2
Mercury Poisoning	1	2
Miscarriage	1	2
Multiple Sclerosis	1	2
Myocardial Infarction	1	2
Myopia	1	2
Neuropathic Pain	1	2
Obsessive-Compulsive Disorder	1	2
Pancreatitis	1	2
Periodontal Diseases	1	2
Pesticide Toxicity	1	2
Polycystic Ovary Syndrome	1	2
Pre-Eclampsia	1	2
Pregnancy Complications	1	2
Prenatal Chemical Exposures	1	2
Prostatic Hyperplasia: Benign	1	2
Pruritus	1	2
Pulmonary Fibrosis: Bleomycin-Induced	1	2
Radiation Induced Illness: Bone Marrow	1	2
Retinal Detachment	1	2
Retinopathy: Hyperoxia-induced	1	2
Seizures	1	2
Sepsis	1	2
Sperm Quality: Low	1	2
Spinal Cord Inflammation	1	2
Thrombosis	1	2
Tobacco Toxicity	1	2
Triglycerides: Elevated	1	2
Ulcerative Colitis	1	2
Uveitis	1	2
Vascular Dementia	1	2
Weight Problems	1	2
Advanced Glycation End products (AGE)	1	1
Autism	1	1
Cancers	1	1
Cardiac Failure	1	1
Copper Toxicity	1	1
Corticosteroid-Induced Toxicity	1	1
Deoxynivalenol Induced Toxicity	1	1
Dopamine Toxicity	1	1
Dry Eye Syndromes	1	1
Glioma	1	1
Hepatitis C	1	1
Hepatoma	1	1
Hyperlipidemia	1	1
Inflammatory Bowel Diseases	1	1
Lead Poisoning	1	1
Leukemia: Acute promyelocytic leukemia	1	1
Mitochondrial Diseases	1	1
Neuroblastoma	1	1
Neurotoxicity	1	1
Ovarian Cancer	1	1
Promyelocytic leukemia	1	1
Pseudomonas aeruginosa	1	1
Sickle Cell Anemia	1	1
Skin Diseases	1	1
Streptococcus pyogenes	1	1
Tumors	1	1

Name	AC	CK
Antioxidants	186	718
Chemopreventive	39	306
Neuroprotective Agents	67	227
Anti-Inflammatory Agents	66	159
Anticarcinogenic Agents	23	99
Cardioprotective	22	89
Apoptotic	37	73
Interleukin-6 Downregulation	22	68
Tumor Necrosis Factor (TNF) Alpha Inhibitor	23	59
NF-kappaB Inhibitor	24	51
Antiproliferative	32	50
Anti-Apoptotic	26	43
Hepatoprotective	23	40
Interleukin-1 beta downregulation	16	40
Photoprotective	12	39
Superoxide Dismutase Up-regulation	12	39
Antihypertensive Agents	7	38
Malondialdehyde Down-regulation	10	38
Telomere Protective	2	30
Nrf2 activation	15	28
Chemosensitizer	14	24
Cyclooxygenase 2 Inhibitors	14	24
Hypolipidemic	9	24
Antineoplastic Agents	9	23
Radioprotective	9	23
Immunostimulatory	5	20
Anti-Fibrotic	9	19
Cell cycle arrest	13	19
Insulin Sensitizers	4	16
Renoprotective	8	16
Antidepressive Agents	3	14
Heme oxygenase-1 up-regulation	9	14
Anti-metastatic	7	12
Enzyme Inhibitors	3	12
Hypoglycemic Agents	2	12
Malonaldehyde (MDA) Down-Regulation	2	12
Chemotherapeutic	9	11
Adiponectin upregulation	1	10
Aromatase Inhibitors	1	10
Ergogenic	1	10
Genoprotective	4	10
Isoprostane Down-Regulation	1	10
Catalase Up-Regulation	4	9
Chemoprotective Agents	5	9
Cytoprotective	6	9
MicroRNA modulator	4	8
Immunomodulatory	4	7
Detoxifier	2	6
Gastroprotective	3	6
Glutathione Upregulation	3	6
Tumor Suppressor Protein p53 Upregulation	4	6
Anti-Bacterial Agents	4	5
Anti-atherogenic	3	5
Interleukin-8 downregulation	3	5
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	3	5
Bcl-2 protein down-regulation	3	4
Hypotensive	2	4
Interleukin-4 downregulation	2	4
Nitric Oxide Inhibitor	2	4
Prophylactic Agents	2	4
Vascular Endothelial Growth Factor Inhibitors	2	4
Anti-Proliferative	1	3
Interleukin-1 alpha downregulation	1	3
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	3
Matrix metalloproteinase-3 (MMP-3) inhibitor	2	3
P21 Activation	3	3
STAT3 Inhibitor	2	3
Vasodilator Agents	2	3
Acetylcholinesterase Inhibitor	1	2
Angiogenesis Inhibitors	1	2
Angiotensin-Converting Enzyme Inhibitors	1	2
Anti-Adipogenic	1	2
Anti-Angiogenic	2	2
Anti-Asthmatic Agents	1	2
Anti-Ulcer Agents	1	2
Anti-thrombotic	1	2
Antioxidant	1	2
Antitussive Agents	1	2
Anxiolytic	1	2
Aphrodisiac	1	2
Autophagy Up-regulation	2	2
Brain-derived neurotrophic factor modulator	1	2
Glutathione Peroxidase 1 (GPx1) Up-Regulation	1	2
Interferon Gamma Reducer	1	2
Interferon-gamma (IFN-gamma) inducer	1	2
Interleukin-10 upregulation	1	2
Interleukin-5 downregulation	1	2
Lipoxygenase Inhibitors	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	2
Matrix metalloproteinase-9 (MMP-9) inhibitor	1	2
Multidrug Resistance Gene Modulators	1	2
Neuritogenic	1	2
Neurogenesis	1	2
Osteoprotective	1	2
P-glycoprotein Inhibitors	1	2
Pancreato Protective Agents	1	2
Radiosensitizer	2	2
Redox Balancer	1	2
Vascular Endothelial Growth Factor C Inhibitor	1	2
apoptosis	1	2
5-alpha reductase inhibitor	1	1
Antimutagenic Agents	1	1
Bax/Bcl2 ratio: Increase	1	1
Caspase-3 Activation	1	1
Cyclin D1 Down-Regulation	1	1
Cytotoxic	1	1
Erk/MAP Inactivation	1	1
Histone deacetylase inhibitor	1	1
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	1	1
Nitric Oxide Enhancer	1	1
P38 Mitogen-Activated Protein Kinase Modulator	1	1
Prostaglandin PGE2 downregulation	1	1
Receptor activator of NF-κB (RANK) gene expression	1	1
Wnt/β-catenin pathway down-regulation	1	1
Wnt/β-catenin signaling pathway modulation	1	1

[+]

Consumption of large amounts of tomato products may be associated with a reduced risk of gastric cancer.Mar 31, 2013

Click here to read the entire abstract

Pubmed Data : Med Hypotheses. 2013 Apr ;80(4):383-8. Epub 2013 Jan 24. PMID: 23352874

Article Published Date : Mar 31, 2013

Study Type : Meta Analysis

Additional Links

Substances : Carotenoids, Lycopene, Tomato

Diseases : Gastric Cancer: Prevention

Pharmacological Actions : Chemopreventive

Additional Keywords : Plant Extracts, Risk Reduction

[+]

Click here to read the entire abstract

Pubmed Data : Skin Pharmacol Physiol. 2013 ;26(1):45-51. Epub 2012 Nov 7. PMID: 23147451

Article Published Date : Dec 31, 2012

Study Type : Human Study

Additional Links

Substances : Carotenoids

Diseases : Alcohol Toxicity , Sunburn

Therapeutic Actions : Sunlight exposure

Additional Keywords : Plant Extracts

Problem Substances : Alcohol Consumption

[+]

An antioxidant formula increases important fat-soluble nutrients and antioxidants and reduces airway inflammation in patients with Cystic Fibrosis. Jan 01, 2008

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Pubmed Data : J Cyst Fibros. 2008 Jan;7(1):60-7. Epub 2007 Jun 13. PMID: 17569601

Click here to read the entire abstract

Pubmed Data : Eur J Nutr. 2010 Dec;49(8):447-57. Epub 2010 Apr 2. PMID: 20361333

Article Published Date : Dec 01, 2010

Study Type : Human Study

Additional Links

Substances : Astaxanthin

Diseases : Immune Disorders: Low Immune Function, Oxidative Stress

Pharmacological Actions : Antioxidants, Immunostimulatory, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Astaxanthin and sesamin supplementation may be a candidate to promote recovery from mental fatigue.Feb 27, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2018 Feb 28 ;10(3). Epub 2018 Feb 28. PMID: 29495607

Article Published Date : Feb 27, 2018

Study Type : Human Study

Additional Links

Substances : Astaxanthin, Sesamin

Diseases : Mental Fatigue

Additional Keywords : Plant Extracts

[+]

Astaxanthin derived from Haematococcus pluvialis improves the skin condition in both women and men.Mar 17, 2012

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Pubmed Data : J Med Food. 2011 Sep 1. Epub 2011 Sep 1. PMID: 21883001

Article Published Date : Sep 01, 2011

Pubmed Data : Arch Otolaryngol Head Neck Surg. 1999 Dec;125(12):1305-10. PMID: 10604407

Article Published Date : Dec 01, 1999

Study Type : Human Study

Additional Links

Substances : beta-Carotene

Diseases : Leukoplakia

[+]

Beta-carotene supplementation ameliorates deficiencies and reduces oxidative stress in Cystic Fibrosis patients. Jan 01, 2000

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Pubmed Data : Ann Nutr Metab. 2000;44(1):30-7. PMID: 10838464

Pubmed Data : Int J Cancer. 2009 Apr 1;124(7):1637-43. PMID: 19089916

Article Published Date : Apr 01, 2009

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Biochem Nutr. 2020 Nov ;67(3):307-316. Epub 2020 Jun 19. PMID: 33293773

Click here to read the entire abstract

Pubmed Data : Food Funct. 2019 Nov 1 ;10(11):7461-7475. Epub 2019 Oct 31. PMID: 31667483

Article Published Date : Oct 31, 2019

Study Type : Human Study

Additional Links

Substances : Crocetin

Diseases : Atherosclerosis, Coronary Artery Disease

Pharmacological Actions : Anti-atherogenic

[+]

Crocetin may have a suppressive effect on myopia progression in children.Aug 06, 2019

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[+]

Fruit and vegetable soups contributed to increasing the concentration of each carotenoid by more than 100% after 3 and 4 weeks of consumption. Feb 29, 2012

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Pubmed Data : Eur J Nutr. 2012 Mar ;51(2):231-9. Epub 2011 Jun 7. PMID: 21647668

Article Published Date : Feb 29, 2012

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Pubmed Data : Am J Clin Nutr. 2009 Nov;90(5):1402-10. Epub 2009 Sep 30. PMID: 19793852

Article Published Date : Nov 01, 2009

Study Type : Human Study

Additional Links

Substances : beta-Carotene, Carotenoids, Lutein, Vitamin C, Vitamin E, Zeaxanthin

Diseases : DNA damage, Radiation Induced Illness

Pharmacological Actions : Antioxidants

[+]

High intake of carotenoid-rich food may play a role in protecting telomeres and regulating telomere length.Jan 26, 2016

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Pubmed Data : Eur J Nutr. 2016 Jan 27. Epub 2016 Jan 27. PMID: 26818530

Article Published Date : Jan 26, 2016

Study Type : Human Study

Additional Links

Substances : Carotenoids

Pharmacological Actions : Telomere Protective

[+]

High intakes of vitamin A, retinol, and provitamin A carotenoids may reduce the risk of gastric cancer.Feb 01, 2007

[+]

In older women, β-carotene levels are independently and inversely associated with estradiol.Jul 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Vitam Nutr Res. 2019 Apr 1:1-8. Epub 2019 Apr 1. PMID: 30932775

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancer Med. 2018 08 ;7(8):4087-4097. Epub 2018 Jul 2. PMID: 29968964

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Substances : Alpha-Carotene, beta-Carotene, Cryptoxanthin, Folate, Lutein, Lycopene, Selenium, Thiamine (B-1) , Vitamin A, Vitamin C, Vitamin E, Zeaxanthin

Diseases : Kidney Cancer

Pharmacological Actions : Chemopreventive

Additional Keywords : Risk Reduction

[+]

Rheumatoid patients subjectively benefited from the vegan diet rich in antioxidants, lactobacilli and fibre.Nov 29, 2000

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Pubmed Data : Toxicology. 2000 Nov 30 ;155(1-3):45-53. PMID: 11156742

Article Published Date : Nov 29, 2000

Study Type : Human Study

Additional Links

Substances : Carotenoids, Fiber, Flavonoids, Lignans

Diseases : Inflammation, Rheumatoid Arthritis

Therapeutic Actions : Dietary Modification: Vegetarian

Pharmacological Actions : Antioxidants

[+]

Safety Study: 6 mg of astaxanthin a day is associated with no adverse effects in humans. Jan 01, 2003

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Pubmed Data : J Med Food. 2003;6(1):51-6. PMID: 12804020

Article Published Date : Jan 01, 2003

Study Type : Human Study

Additional Links

Substances : Astaxanthin

[+]

Serum carotenoids are inversely associated with prevalence of NAFLD in middle aged and elderly Chinese.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Pediatr. 2012 Jul ;161(1):58-64.e1-2. Epub 2012 Feb 28. PMID: 22381025

Article Published Date : Jun 30, 2012

Study Type : Human Study

Additional Links

Substances : beta-Carotene, Fruit: All, Vegetables: All

Diseases : Insulin Resistance, Overweight

Pharmacological Actions : Insulin Sensitizers

Additional Keywords : Anti-Obesity Agents, Fruit Juice, Vegetable Juice

[+]

Supplementation with lutein and zeaxanthin improves CNS xanthophyll levels and cognitive function in healthy adults.Nov 13, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2017 Nov 14 ;9(11). Epub 2017 Nov 14. PMID: 29135938

Click here to read the entire abstract

Pubmed Data : Curr Eye Res. 2010 Apr;35(4):335-51. PMID: 20373901

Article Published Date : Apr 01, 2010

Study Type : Human Study

Additional Links

Substances : Carotenoids, Lutein, Zeaxanthin

Diseases : Macular Degeneration

[+]

Additional Keywords : Risk Reduction

[+]

Click here to read the entire abstract

Pubmed Data : J Affect Disord. 2015 Mar 15 ;174:51-6. Epub 2014 Nov 26. PMID: 25484177

Article Published Date : Mar 14, 2015

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Pubmed Data : Br J Nutr. 2020 Apr 30:1-31. Epub 2020 Apr 30. PMID: 32349798

Article Published Date : Apr 29, 2020

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Pubmed Data : J Hypertens. 2019 Jul 26. Epub 2019 Jul 26. PMID: 31356404

Article Published Date : Jul 25, 2019

Study Type : Human Study

Additional Links

Substances : Alpha-Carotene, beta-Carotene, Carotenoids, Cryptoxanthin, Lutein, Lycopene, Zeaxanthin

Diseases : Hypertension

Additional Keywords : Risk Reduction

[+]

Vegetables and fruits rich in lycopene and other carotenoids may be protective against prostate cancer.Mar 01, 2005

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Pubmed Data : Int J Cancer. 2005 Mar 1;113(6):1010-4. PMID: 15514967

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Pubmed Data : Eur J Nutr. 2016 Feb ;55(1):171-82. Epub 2015 Jan 17. PMID: 25595100

Article Published Date : Feb 01, 2016

Study Type : Human In Vitro

Additional Links

Substances : Anthocyanins, Blueberry, Carotenoids, Fiber

Diseases : Atherosclerosis

Pharmacological Actions : Antioxidants

Additional Keywords : Plant Extracts

[+]

Astaxanthin could be useful for improving chronic inflammation such as that associated with oral lichen planus.Apr 30, 2015

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Pubmed Data : Avicenna J Med Biotechnol. 2018 Apr-Jun;10(2):69-74. PMID: 29849982

Article Published Date : Apr 01, 2018

Study Type : Human In Vitro

Additional Links

Substances : Astaxanthin

Pharmacological Actions : Regenerative

Additional Keywords : Nerve Regeneration

[+]

Enhanced proliferation and differentiation of mesenchymal stem cells by astaxanthin-encapsulated polymeric micelles.Jan 01, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Nutrients. 2017 Mar 13 ;9(3). Epub 2017 Mar 13. PMID: 28335388

Article Published Date : Mar 12, 2017

Study Type : Animal Study

Additional Links

Substances : Astaxanthin, Flaxseed Oil

Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD), Oxidative Stress

Pharmacological Actions : Antioxidants, Hepatoprotective, Hypolipidemic

[+]

A variety of carotenoids induce reduce resistance to chemotherapy in multidrug resistant lymphoma and human breast cancer cell lines. Mar 01, 2004

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Pubmed Data : In Vivo. 2004 Mar-Apr;18(2):237-44. PMID: 15113052

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Med Rep. 2020 Dec ;22(6):5271-5281. Epub 2020 Oct 14. PMID: 33173984

Pubmed Data : Free Radic Res. 2012 Mar ;46(3):329-38. Epub 2012 Feb 6. PMID: 22239725

Article Published Date : Feb 29, 2012

Study Type : Animal Study

Additional Links

Substances : Achiote, beta-Carotene

Diseases : Diabetes Mellitus: Type 2, Oxidative Stress

Pharmacological Actions : Antioxidants, Catalase Up-Regulation, MicroRNA modulator, Superoxide Dismutase Up-regulation

Additional Keywords : Gene Expression Regulation, Plant Extracts

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Anti-diabetic effects of astaxanthin on an STZ-induced diabetic model in rats.Dec 01, 2020

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Pubmed Data : Mediators Inflamm. 2014 ;2014:954502. Epub 2014 Apr 17. PMID: 24860243

Article Published Date : Dec 31, 2013

Study Type : Animal Study

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Substances : Astaxanthin

Diseases : Liver Fibrosis

Pharmacological Actions : Anti-Apoptotic, Anti-Fibrotic

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Astaxanthin improves cognitive deficits from oxidative stress in diabetes rats.Dec 31, 2014

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Pubmed Data : Biol Pharm Bull. 2006 Oct;29(10):2106-10. PMID: 17015959

Article Published Date : Oct 01, 2006

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Athletic Performance

Additional Keywords : Enhanced Lipid Utilization

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The Following are Sub-Topics of Carotenoids

View the Evidence: 791 Abstracts with Carotenoids Research

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Consumption of large amounts of tomato products may be associated with a reduced risk of gastric cancer.Mar 31, 2013

Dietary vitamin and carotenoid intake and risk of age-related cataract.Jan 08, 2019

Higher blood concentrations of lutein are generally associated with better cardiometabolic health.Jan 12, 2016

Higher concentrations of plasma carotenoids may reduce risk of urothelial cell carcinoma (UCC), in particular aggressive UCC.Sep 30, 2012

Higher dietary intakes of selenium, vitamin C, vitamin E, β-carotene and β-cryptoxanthin were associated with reduced pancreatic cancer risk.Jun 29, 2016

Higher intake of vitamin C, carotenoids, and α- tocopherol were associated with reduced risk of cardiovascular disease, total cancer, and all-cause mortality.Oct 31, 2018

Higher vitamin C intake and higher circulating concentrations of vitamin C, vitamin E and β-carotene are associated with a lower risk of CVD mortality.Jan 10, 2019

This meta-analysis suggests that blood retinol level is a double-edged sword for risk of hip fracture.Aug 31, 2014

Decreased intake of vegetables and fruits during pregnancy and the consequent decreased intake of nutrients such as folate and lutein/zeaxanthin, necessary for DNA methylation, synthesis, and retinal function, may increase risk for having a child with spJun 01, 2005

The effect of astaxanthin supplementation on performance and fat oxidation during a 40 km cycling time trial Jul 02, 2020

A blackcurrant product regulated the microbiota of volunteers and decreased the activity of βeta glucuronidase.Feb 28, 2014

A combination of nutrients improves age-related macular degeneration. Feb 01, 2008

A diet rich in linoleic acid containing foods (e.g. white meats and fish) and beta-carotene was inversely related to HCC risk; iron intake was associated with increased risk. Nov 01, 2007

A dietary supplement containing astaxanthin and saw palmetto berry extract decrease dihydrotestosterone, increase testosterone and decrease estradiol levels in healthy males. Sep 01, 2009

A formula containing calcium, vitamin D3, lycopene , astaxantin and citrus bioflavonoids reducing climacteric symptoms in menopausal women. Jun 01, 2010

Additional consumption of one egg per day increases serum lutein plus zeaxanthin concentration and lowers oxidized low-density lipoprotein.Aug 31, 2017

Alcohol consumption decreases the protection efficiency of the antioxidant network and increases the risk of sunburn in human skin.Dec 31, 2012

An antioxidant formula increases important fat-soluble nutrients and antioxidants and reduces airway inflammation in patients with Cystic Fibrosis. Jan 01, 2008

Antioxidant supplementation may have therapeutic value in the treatment of cystic fibrosis - Article 2. Jan 01, 2003

Antioxidant supplements prevent oxidation of cysteine/cystine redox in patients with age-related macular degeneration.Dec 01, 2005

Astaxanthin addition improves human neutrophils function.Dec 01, 2010

Astaxanthin and sesamin supplementation may be a candidate to promote recovery from mental fatigue.Feb 27, 2018

Astaxanthin derived from Haematococcus pluvialis improves the skin condition in both women and men.Mar 17, 2012

Astaxanthin has a positive effect on lipid profiles and oxidative stress in overweight subjects. Oct 01, 2011

Astaxanthin has antioxidant properties in soccer players.Nov 27, 2012

Astaxanthin improves glucose metabolism and reduces blood pressure in patients with type 2 diabetes mellitus.Dec 31, 2017

Astaxanthin improves human sperm capacitation by inducing lyn displacement and activation.Aug 24, 2015

Astaxanthin improves oxidative stress in overweight and obese adults. Apr 08, 2011

Astaxanthin increases blood flow in the eyes as measured by increased choroidal blood flow velocity.Nov 10, 2011

Astaxanthin prevents in vitro auto-oxidative injury in human lymphocytes.Oct 01, 2010

Astaxanthin protects smokers against oxidative stress. Sep 01, 2011

Astaxanthin reduces reflux symptoms in patients, especially in those with pronounced H. pylori infection.Jun 01, 2008

Astaxanthin seems protective against UV-induced skin deterioration and helps maintain healthy skin in healthy people.Jun 24, 2018

Astaxanthin significantly improves athletic performance as measured by cycling time. Oct 07, 2011

Astaxanthin supplementation improves sIgA response and attenuates muscle damage, thus preventing inflammation induced by rigorous physical training.Dec 31, 2014

Astaxanthin supplementation may have a beneficial effect on muscle damage and oxidative stress markers in atheletes. Jul 31, 2012

Astaxanthin supplementation reduces lipid peroxidation. Jan 01, 2007

Astaxanthin supplementation results in measurable improvement in the antioxidant status of human subjects. Jan 01, 2011

Astaxanthin-rich Haematococcus pluvialis extract improves cognitive function in the healthy aged individuals.Aug 31, 2012

Beta-carotene has therapeutic value in the treatment of leukoplakias.Dec 01, 1999

Beta-carotene supplementation ameliorates deficiencies and reduces oxidative stress in Cystic Fibrosis patients. Jan 01, 2000

Beta-carotene, vitamin C and vitamin E deficiencies may play a role in the pathogenesis of thyroid cancer. Jun 01, 1997

Bioavailability Study: Administration After-Meal Significantly Improves Availability. Sep 01, 2009

Breast cancer risk may be affected by telomere length among premenopausal women or women with low dietary intake of antioxidants or antioxidant supplements. Apr 01, 2009

Carotenoids such as lycopene have a protective effect on bone health.Jun 01, 2009

Carotenoids, Vitamin C and E, reduce the risk of cataracts in women. Jan 01, 2008

Co-consuming cooked whole eggs is an effective way to enhance carotenoid absorption from other carotenoid-rich foods.May 26, 2015

Cognitive function improvement with astaxanthin and tocotrienol intake.Oct 31, 2020

Consumption of watermelon juice increases plasma concentrations of lycopene and beta-carotene in humans.Apr 01, 2003

Continuous astaxanthin consumption produces a strong antioxidant effect resulting in facial skin rejuvenation.Nov 30, 2017

crocetin could be considered as a promising anti-atherogenic candidate for future studies.Oct 31, 2019

Crocetin may have a suppressive effect on myopia progression in children.Aug 06, 2019

Daily consumption of a lutein-enriched egg drink for one year leads to a significant increase in visual acuity.Dec 31, 2015

Daily supplementation with carotenoids protects human skin against both UVB-induced erythema and UVA-induced pigmentation.Feb 17, 2020

Daily use of vitamin E, Vitamin C, and beta-carotene for three years produces a small deceleration in the progression of age-related cataract.Oct 01, 2001

Dietary antioxidants and fiber intake and depressive symptoms in Iranian adolescent girls.Nov 30, 2020

Dietary carotenoids lutein and zeaxanthin change brain activation in older adult participants.Apr 04, 2019

Dietary consumption of fruits high in antioxidant nutrients reduce the risk of incident cervical intraepithelial neoplasia.Sep 01, 2010

Dietary intake of B vitamins may affect the occurrence of age-related lens opacities. Jun 30, 2015

Dietary intake of carotenoids reduce the risk of endometrial cancer. Dec 01, 2008

Dietary interventions with carotenoids, fruits and vegetables may affect the insulin-like growth factor system.Dec 31, 2015

Dietary nutrient intake was associated with open-angle glaucoma independent of intraocular pressure.Mar 21, 2018

Eating a diet rich in carotenoids might help prevent the development of the MetS and its complications in Japanese subjects.Sep 13, 2015

Egg consumption in U.S. children is associated with greater daily nutrient intakes.May 21, 2019

Following 3-month astaxanthin supplementation, suppressed oxidative stress and improved cardiac contractility and exercise tolerance.Jun 25, 2020

Fruit and vegetable consumption may reduce the risk of renal cell cancer in men.Dec 01, 2006

Fruit and vegetable soups contributed to increasing the concentration of each carotenoid by more than 100% after 3 and 4 weeks of consumption. Feb 29, 2012

Genotype may codetermine potential vitamin A side effects on retinal integrity.Jan 31, 2012

High antioxidant intake is associated with lower blood concentrations of C-reactive protein and plasma homocysteine concentrations in US adults.cMar 18, 2011

High combined intakes of vitamins C and E, beta-carotene, beta-cryptoxanthin, and lutein-zeaxanthin from food, or a diet high in their food sources, may protect against cumulative DNA damage in ionizing radiation persons.Nov 01, 2009

High intake of carotenoid-rich food may play a role in protecting telomeres and regulating telomere length.Jan 26, 2016

High intakes of vitamin A, retinol, and provitamin A carotenoids may reduce the risk of gastric cancer.Feb 01, 2007

Carotenoids

View the Evidence:
791 Abstracts with Carotenoids Research