Carotenoids

Name	AC	CK
Oxidative Stress	106	289
Breast Cancer	27	165
Macular Degeneration	21	156
Cognitive Decline/Dysfunction	18	138
Inflammation	37	107
Alzheimer's Disease	29	94
Nonalcoholic fatty liver disease (NAFLD)	12	87
Cataract	14	85
Breast Cancer: Prevention	5	82
Cardiovascular Diseases	20	82
DNA damage	16	82
Hypertension	10	75
Obesity	18	67
Gastric Cancer	7	54
Diabetes Mellitus: Type 2	14	52
Kidney Cancer	2	50
Lipid Peroxidation	18	49
Lung Cancer	11	49
Radiation Induced Illness	5	47
Aging: Brain	5	45
Ultraviolet Radiation Induced Damage	16	45
Athletic Performance	6	44
Cancers: All	26	43
Depression	9	42
Prostate Cancer	13	42
Coronary Artery Disease	4	41
Endometrial Cancer	3	40
Prostate Cancer: Prevention	1	40
Memory Disorders	7	39
Insulin Resistance	10	34
C-Reactive Protein	4	32
Overweight	4	32
Pancreatic Cancer	3	32
Smoking	4	31
Atherosclerosis	10	30
Cystic Fibrosis	3	30
Non-Hodgkin Lymphoma	1	30
Vision Disorders	2	30
Vision Loss	2	30
Alcohol Toxicity	12	29
Colon Cancer	11	29
Eye Diseases	6	28
Diabetic Retinopathy	14	26
Helicobacter Pylori Infection	12	25
Immune Disorders: Low Immune Function	4	25
Stroke	3	25
Vitamin A Deficiency	4	25
Dementia	4	24
Diabetic Complications	12	24
Human Papillomavirus (HPV)	4	23
Osteoporosis	4	23
High Homocysteine	3	22
Learning disorders	2	22
Lipopolysaccharide-Induced Toxicity	14	22
Muscle Damage: Exercise-Induced	3	22
Parkinson's Disease	14	22
Aging Skin	3	21
Diabetes Mellitus: Type 1	5	21
All-Cause Mortality	1	20
Bladder Cancer: Prevention	1	20
Bone Fractures	1	20
Cancer Mortality	1	20
Cardiac Mortality	1	20
Gastric Cancer: Prevention	1	20
High Fat Diet	10	20
Hypercholesterolemia	1	20
Liver Cancer	14	20
Metabolic Diseases	1	20
Retinoblastoma	1	20
Visual Display Terminal Eye Fatigue	1	20
Glaucoma	6	19
Liver Cancer: Prevention	4	19
Brain Inflammation	11	18
Cervical Cancer	7	17
Infertility: Male	5	17
Lung Cancer: Prevention	2	16
Metabolic Syndrome X	4	16
Neurodegenerative Diseases	14	16
Sunburn	3	16
Aging	9	15
Diabetic Nephropathy	9	15
Periodontitis	4	15
Cerebral Ischemia	8	14
Kidney Damage	8	14
Myopia	3	14
Sleep Disorders	2	14
Atopic Dermatitis	7	13
Chemotherapy-Induced Toxicity: Cisplatin	7	13
Colorectal Cancer	9	13
Cancers: Multi-Drug Resistant	7	12
Erythema	2	12
Glioblastoma	6	12
Heart Failure	2	12
Liver Fibrosis	8	12
Retinal Diseases	2	12
Uterine Cervical Neoplasms	2	12
Acid Reflux	2	11
Brain: Oxidative Stress	6	11
Hearing Loss	2	11
Photooxidative Stress	5	11
Rheumatoid Arthritis	2	11
AST: Elevated	1	10
Alcoholic Liver Disease	5	10
Apolipoprotein A/B ratio imbalances	1	10
Bladder Cancer	1	10
Cervical Dysplasia	1	10
Chemotherapy and Radiation Toxicity	4	10
Cholesterol: LDL/HDL ratio	1	10
Clostridium Infections	1	10
Colon Cancer: Prevention	1	10
Common variable immunodeficiency (CVID)	1	10
Computer display light exposure	1	10
Creatine Phosphokinase (CK): Elevated	1	10
Diabetes Insipidus	1	10
Diabetes Mellitus: Type 2: Prevention	1	10
Diabetes: Oxidative Stress	5	10
Eye Diseases: Lack of Blood Circuation	1	10
Fatty Liver	6	10
Infant Nutrition	1	10
Leukoplakia	1	10
Low Testosterone	1	10
Male Hormone Imbalances	1	10
Menopausal Syndrome	1	10
Mental Fatigue	1	10
Periodontal Wound Healing	1	10
Phthalate Toxicity	1	10
Pneumonia	1	10
Spinal Cord Injuries	5	10
Testosterone: Too Low	1	10
Thyroid Cancer	1	10
Visual Fatigue	1	10
Brain Injury: Traumatic	5	9
High Fructose Diet	4	9
Oral Cancer	4	9
Burns	4	8
Cardiac Hypertrophy	3	8
Chemically-Induced Liver Damage	4	8
Eye Damage	3	8
Ischemia	4	8
Liver Damage	6	8
Muscle Atrophy	4	8
Wound Healing	5	8
Asthma	5	7
Esophageal Cancer	6	7
Fructose-Induced Toxicity	3	7
Kidney Fibrosis	4	7
Lung Injury: Acute	4	7
Myocardial Fibrosis	2	7
Sepsis	4	7
Subarachnoid hemorrhage	4	7
Chemotherapy-Induced Toxicity: Cyclophosphamide	3	6
Gastric Ulcer	3	6
Hydrogen Peroxide Induced Toxicity	6	6
Hyperglycemia	3	6
Hypoxia	4	6
Liver Damage: Drug-Induced	3	6
Mitochondrial Dysfunction	4	6
Myocardial Ischemia	4	6
Polycystic Ovary Syndrome	3	6
Retinitis Pigmentosa	2	6
Skin Cancer: Prevention	1	6
Squamous cell carcinoma	2	6
Xenobiotic Exposures	2	6
Advanced Glycation Endproduct (AGE) Formation	1	5
Air Pollution Linked Toxicity	3	5
Arthritis	3	5
Breast Cancer: Triple Negative	3	5
Cancers: Drug Resistant	4	5
Drug Toxicity: Methotrexate	3	5
Endothelial Dysfunction	3	5
Neutrophils: Damaged	1	5
Oral Lichen Planus	1	5
Skin Cancer	2	5
Acetaminophen (Tylenol) Toxicity	2	4
Arsenic Poisoning	2	4
Autoimmune Diseases	1	4
Cancer Metastasis	3	4
Chemotherapy-Induced Toxicity: Doxorubicin	2	4
Cholesterol: Oxidation	2	4
Colitis	2	4
Delayed Sleep Phase Disorder	1	4
Diabetes: Cardiovascular Illness	2	4
Drug-Induced Toxicity: Methotrexate	2	4
Dyslipidemias	2	4
Epilepsy	2	4
Insomnia	1	4
Kidney Damage: Chemically-Induced	2	4
Leukemia	2	4
Liver Injury: Ischemia/reperfusion	2	4
Low Immune Function: Splenic Dysfunction	1	4
Lung Damage	2	4
Lymphadenopathy	1	4
Lymphoma	1	4
Maculopathy: Age-Related	1	4
Melanoma	2	4
Middle Cerebral Artery Occlusion (MCAO)	2	4
Multiple Sclerosis	2	4
Myocardial Infarction	2	4
Osteoarthritis	3	4
Pancreatitis	2	4
Photokeratitis	2	4
Proteinuria	1	4
Retinal Degeneration: Light-Induced	2	4
Stress	2	4
Stroke: Prevention	2	4
Testicular Injury: Chemical/Metal Induced	2	4
Tongue Cancer	1	4
Tracheal Cancer	1	4
Traumatic Brain Injury	2	4
Blue Light Toxicity	2	3
Carcinoma: Non-Small-Cell Lung	3	3
Chronic Kidney Disease (CKD)	2	3
Coronavirus Infection	3	3
Diabetes: Cognitive Dysfunction	2	3
Fibrosis	2	3
Homocysteine: Elevated	2	3
Iron Overload	1	3
Iron Poisoning	1	3
Leukemia: Acute promyelocytic leukemia	2	3
Pre-Eclampsia	2	3
Skin Diseases: Photo-Aging	2	3
Aflatoxicosis	1	2
Agent Orange Toxicity	1	2
Aging: Heart	1	2
Allergic Airway Diseases	1	2
Aluminum Toxicity	1	2
Arterial Hardening: Elasticity	1	2
Aspirin-Induced Toxicity	1	2
Benzo[a]pyrene-induced Toxicity	1	2
Bisphenol Toxicity	1	2
Bladder Outlet Obstruction	1	2
Blindness	1	2
Blood Pressure: High	1	2
Brain Ischemia	1	2
Breast Cancer: Chemically-Induced	1	2
Cachexia	1	2
Cadmium Poisoning	1	2
Cancer Stem Cells	2	2
Cardiomegaly	1	2
Cardiomyopathy	1	2
Chemotherapy-Induced Toxicity: Arsenic Trioxide	1	2
Chemotherapy-Induced Toxicity: Gentamicin	1	2
Chemotherapy-Induced Toxicity: Kidney	1	2
Chronic Obstructive Pulmonary Disease	1	2
Chronic Pain	1	2
Coenzyme Q10 Deficiency	1	2
Cough	1	2
Dengue	1	2
Dental Caries	1	2
Dental Diseases	1	2
Diabetes: Cataract	1	2
Diabetes: Dental Problems	1	2
Diabetes: Immune Problems	1	2
Diabetes: Low Immune Function	1	2
Drug-Induced Toxicity: Indomethacin	1	2
Dry Eye Syndromes	2	2
Dysbiosis	1	2
Exercise-Induced Tissue Damage	1	2
Fibrosarcoma	1	2
Fulminant Hepatic Failure	1	2
Gastrointestinal Inflammation	1	2
Gestational Diabetes	1	2
Hepatic Steatosis	1	2
High Cholesterol	1	2
High Sugar Diet	1	2
Hyperhomocysteinemia	1	2
Hyperuricemia	1	2
Hypothyroidism	1	2
Immune Dysregulation: TH1 dominance	1	2
Infertility: Female	1	2
Intestinal Injury	1	2
Intima Media Thickening	1	2
Intraocular hypertension	1	2
Keratitis	1	2
Kidney Damage: Drug-Induced	1	2
Kidney Diseases	1	2
Liver Cirrhosis	1	2
Liver Damage: Aflatoxin-Induced	1	2
Low Libido	1	2
Mastocytoma	1	2
Memory Loss	1	2
Mercury Poisoning	1	2
Miscarriage	1	2
Necrotising enterocolitis	1	2
Neuropathic Pain	1	2
Obsessive-Compulsive Disorder	1	2
Osteopenia	1	2
Ovarian Cancer	2	2
Periodontal Diseases	1	2
Pesticide Toxicity	1	2
Pregnancy Complications	1	2
Prenatal Chemical Exposures	1	2
Prostatic Hyperplasia: Benign	1	2
Pruritus	1	2
Pulmonary Fibrosis: Bleomycin-Induced	1	2
Radiation Induced Illness: Bone Marrow	1	2
Retinal Detachment	1	2
Retinopathy: Hyperoxia-induced	1	2
Seizures	1	2
Skin Diseases	2	2
Sperm Quality: Low	1	2
Spinal Cord Inflammation	1	2
Stroke: Ischemic	1	2
Thrombosis	1	2
Tobacco Toxicity	1	2
Triglycerides: Elevated	1	2
Ulcerative Colitis	1	2
Uveitis	1	2
Vascular Dementia	1	2
Weight Problems	1	2
Advanced Glycation End products (AGE)	1	1
Alzheimer's Disease: Homocysteine Associated	1	1
Autism	1	1
Cancers	1	1
Cardiac Failure	1	1
Central Nervous System Diseases	1	1
Chronic Disease	1	1
Copper Toxicity	1	1
Corticosteroid-Induced Toxicity	1	1
Deoxynivalenol Induced Toxicity	1	1
Dopamine Toxicity	1	1
Dry Skin	1	1
Endometritis	1	1
Endothelial Damage	1	1
Gastrointestinal Diseases	1	1
Glioma	1	1
Glomerulosclerosis	1	1
Hepatitis C	1	1
Hepatoma	1	1
Hyperlipidemia	1	1
Inflammatory Bowel Diseases	1	1
Lead Poisoning	1	1
Liver Disease	1	1
Liver Diseases	1	1
Lung Diseases	1	1
Mitochondrial Diseases	1	1
Nasopharyngeal Cancer	1	1
Neuroblastoma	1	1
Neurological Conditions	1	1
Neurotoxicity	1	1
Promyelocytic leukemia	1	1
Pseudomonas aeruginosa	1	1
Pulmonary Fibrosis	1	1
Radiation	1	1
Sickle Cell Anemia	1	1
Staphylococcus aureus infection	1	1
Staphylococcus epidermidis	1	1
Streptococcus pyogenes	1	1
Tumors	1	1
Vascular Calcification	1	1
Zinc Deficiency	1	1

Name	AC	CK
Antioxidants	306	981
Chemopreventive	51	423
Neuroprotective Agents	112	383
Anti-Inflammatory Agents	149	319
Hepatoprotective	39	127
Cardioprotective	40	124
Interleukin-6 Downregulation	42	108
Anticarcinogenic Agents	26	105
Apoptotic	53	95
Tumor Necrosis Factor (TNF) Alpha Inhibitor	41	92
Anti-Apoptotic	49	82
Interleukin-1 beta downregulation	38	79
Antiproliferative	53	78
Nrf2 activation	44	76
NF-kappaB Inhibitor	37	74
Photoprotective	18	56
Heme oxygenase-1 up-regulation	26	44
Antihypertensive Agents	9	41
Malondialdehyde Down-regulation	12	41
Superoxide Dismutase Up-regulation	13	41
Antidepressive Agents	7	38
Renoprotective	20	36
Hypolipidemic	16	35
Cyclooxygenase 2 Inhibitors	18	30
Telomere Protective	2	30
Immunomodulatory	14	29
Regenerative	6	27
Chemosensitizer	16	26
Anti-Fibrotic	13	25
Cytoprotective	10	24
MicroRNA modulator	9	24
Radioprotective	10	24
Antineoplastic Agents	9	23
Anti-metastatic	15	22
Cell cycle arrest	15	21
Hypoglycemic Agents	7	21
Immunostimulatory	5	20
Chemoprotective Agents	10	19
Insulin Sensitizers	5	17
Anti-atherogenic	4	15
Chemotherapeutic	13	15
Osteoprotective	4	15
Gastrointestinal Agents	8	14
Gastroprotective	7	13
Interferon Gamma Reducer	3	13
Enzyme Inhibitors	3	12
Malonaldehyde (MDA) Down-Regulation	2	12
Catalase Up-Regulation	5	11
Adiponectin upregulation	1	10
Aromatase Inhibitors	1	10
Ergogenic	1	10
Genoprotective	4	10
Isoprostane Down-Regulation	1	10
Interleukin-4 downregulation	4	8
Bcl-2 protein down-regulation	5	7
Brain-derived neurotrophic factor modulator	3	7
Interleukin-8 downregulation	5	7
Anti-Bacterial Agents	5	6
Autophagy Up-regulation	5	6
Detoxifier	2	6
Glutathione Upregulation	3	6
Prophylactic Agents	3	6
Tumor Suppressor Protein p53 Upregulation	4	6
Angiogenesis Inhibitors	3	5
Interleukin-5 downregulation	3	5
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	3	5
Matrix metalloproteinase-9 (MMP-9) inhibitor	3	5
Vascular Endothelial Growth Factor Inhibitors	3	5
Anti-Asthmatic Agents	2	4
Glutathione Peroxidase 1 (GPx1) Up-Regulation	2	4
Hypotensive	2	4
Matrix metalloproteinase-1 (MMP-1) inhibitor	3	4
Nitric Oxide Inhibitor	2	4
Pancreato Protective Agents	2	4
Radiosensitizer	3	4
STAT3 Inhibitor	3	4
Anti-Proliferative	1	3
Fertility Agents: Male	2	3
Interleukin-1 alpha downregulation	1	3
Matrix metalloproteinase-3 (MMP-3) inhibitor	2	3
Multidrug Resistance Gene Modulators	2	3
P21 Activation	3	3
Vasodilator Agents	2	3
Acetylcholinesterase Inhibitor	1	2
Angiotensin-Converting Enzyme Inhibitors	1	2
Anti-Adipogenic	1	2
Anti-Angiogenic	2	2
Anti-Ulcer Agents	1	2
Anti-thrombotic	1	2
Anticholesteremic Agents	1	2
Antinoceceptive	1	2
Antioxidant	1	2
Antitussive Agents	1	2
Anxiolytic	1	2
Aphrodisiac	1	2
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	2	2
Interferon-gamma (IFN-gamma) inducer	1	2
Interleukin-10 upregulation	1	2
Lipoxygenase Inhibitors	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	2
Neuritogenic	1	2
Neurogenesis	1	2
P-glycoprotein Inhibitors	1	2
Postaglandin PGE2 downregulation	1	2
Redox Balancer	1	2
Uricosuric Agents	1	2
Vascular Endothelial Growth Factor C Inhibitor	1	2
Xanthine oxidase inhibitor	1	2
apoptosis	1	2
5-alpha reductase inhibitor	1	1
Antimicrobial	1	1
Antimutagenic Agents	1	1
Antiviral Agents	1	1
Bax/Bcl2 ratio: Increase	1	1
Caspase-3 Activation	1	1
Cyclin D1 Down-Regulation	1	1
Cytotoxic	1	1
Erk/MAP Inactivation	1	1
Histone deacetylase inhibitor	1	1
Interleukin-12 downregulation	1	1
Nitric Oxide Enhancer	1	1
P38 Mitogen-Activated Protein Kinase Modulator	1	1
Prostaglandin PGE2 downregulation	1	1
Receptor activator of NF-κB (RANK) gene expression	1	1
Transforming growth factor beta (TGF-β) inhibitor	1	1
Wnt/β-catenin pathway down-regulation	1	1
Wnt/β-catenin signaling pathway modulation	1	1
interleukin-13 down-regulation	1	1

Carotenoids supplementation and inflammation.May 16, 2021

Click here to read the entire abstract

Pubmed Data : Crit Rev Food Sci Nutr. 2021 May 17:1-17. Epub 2021 May 17. PMID: 33998846

Article Published Date : May 16, 2021

Study Type : Meta Analysis, Review

Additional Links

Substances : Carotenoids

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Consumption of large amounts of tomato products may be associated with a reduced risk of gastric cancer.Mar 31, 2013

Click here to read the entire abstract

Pubmed Data : Med Hypotheses. 2013 Apr ;80(4):383-8. Epub 2013 Jan 24. PMID: 23352874

Article Published Date : Mar 31, 2013

Study Type : Meta Analysis

Additional Links

Substances : Carotenoids, Lycopene, Tomato

Diseases : Gastric Cancer: Prevention

Pharmacological Actions : Chemopreventive

Additional Keywords : Plant Extracts, Risk Reduction

[+]

A combination of nutrients improves age-related macular degeneration. Feb 01, 2008

A dietary supplement containing astaxanthin and saw palmetto berry extract decrease dihydrotestosterone, increase testosterone and decrease estradiol levels in healthy males. Sep 01, 2009

Click here to read the entire abstract

Pubmed Data : J Cardiovasc Electrophysiol. 2009 Sep;20(9):1055-60. Epub 2009 Apr 30. PMID: 18700016

Article Published Date : Sep 01, 2009

Click here to read the entire abstract

Pubmed Data : Food Res Int. 2017 Sep ;99(Pt 2):944-949. Epub 2017 Mar 4. PMID: 28847431

Article Published Date : Aug 31, 2017

Study Type : Human Study

Additional Links

Substances : Egg, Lutein, Zeaxanthin

Diseases : Hypercholesterolemia

Pharmacological Actions : Malondialdehyde Down-regulation

[+]

Alcohol consumption decreases the protection efficiency of the antioxidant network and increases the risk of sunburn in human skin.Dec 31, 2012

Click here to read the entire abstract

Pubmed Data : Skin Pharmacol Physiol. 2013 ;26(1):45-51. Epub 2012 Nov 7. PMID: 23147451

Article Published Date : Dec 31, 2012

Study Type : Human Study

Additional Links

Substances : Carotenoids

Diseases : Alcohol Toxicity , Sunburn

Therapeutic Actions : Sunlight exposure

Additional Keywords : Plant Extracts

Problem Substances : Alcohol Consumption

[+]

An antioxidant formula increases important fat-soluble nutrients and antioxidants and reduces airway inflammation in patients with Cystic Fibrosis. Jan 01, 2008

Click here to read the entire abstract

Pubmed Data : J Cyst Fibros. 2008 Jan;7(1):60-7. Epub 2007 Jun 13. PMID: 17569601

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Antioxidant formulas, Carotenoids, Coenzyme Q10, Vitamin E

Diseases : Cystic Fibrosis

Pharmacological Actions : Antioxidants

[+]

Annatto carotenoids attenuate oxidative stress and inflammatory response after high-calorie meal in healthy subjects.Jan 09, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Food Res Int. 2017 10 ;100(Pt 1):771-779. Epub 2017 Aug 3. PMID: 28873749

Article Published Date : Jan 09, 2017

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2012 Nov 28. Epub 2012 Nov 28. PMID: 23192897

Article Published Date : Nov 27, 2012

Study Type : Human Study

Additional Links

Substances : Astaxanthin

Diseases : Athletic Performance, Oxidative Stress

Pharmacological Actions : Antioxidants

[+]

Astaxanthin improves glucose metabolism and reduces blood pressure in patients with type 2 diabetes mellitus.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : J Med Food. 2011 Sep 1. Epub 2011 Sep 1. PMID: 21883001

Astaxanthin treatment ameliorates ER stress in polycystic ovary syndrome patients.Feb 27, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancer. 1997 Jun 1;79(11):2186-92. PMID: 9179066

Article Published Date : Jun 01, 1997

Study Type : Human Study

Additional Links

Substances : beta-Carotene, Vitamin C, Vitamin E

Diseases : Thyroid Cancer

[+]

Bioavailability Study: Administration After-Meal Significantly Improves Availability. Sep 01, 2009

Click here to read the entire abstract

Pubmed Data : Biosci Biotechnol Biochem. 2009 Sep;73(9):1928-32. Epub 2009 Sep 7. PMID: 19734684

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Substances : Astaxanthin

Additional Keywords : Plant Extracts

[+]

Breast cancer risk may be affected by telomere length among premenopausal women or women with low dietary intake of antioxidants or antioxidant supplements. Apr 01, 2009

Click here to read the entire abstract

Pubmed Data : Int J Cancer. 2009 Apr 1;124(7):1637-43. PMID: 19089916

Article Published Date : Apr 01, 2009

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Biochem Nutr. 2020 Nov ;67(3):307-316. Epub 2020 Jun 19. PMID: 33293773

Click here to read the entire abstract

Pubmed Data : Food Funct. 2019 Nov 1 ;10(11):7461-7475. Epub 2019 Oct 31. PMID: 31667483

Article Published Date : Oct 31, 2019

Study Type : Human Study

Additional Links

Substances : Crocetin

Diseases : Atherosclerosis, Coronary Artery Disease

Pharmacological Actions : Anti-atherogenic

[+]

Crocetin may have a suppressive effect on myopia progression in children.Aug 06, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

[+]

Efficacy and safety of a krill oil, astaxanthin, and oral hyaluronic acid complex on joint health in people with mild osteoarthritis.Aug 28, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2023 Aug 29 ;15(17). Epub 2023 Aug 29. PMID: 37686801

Article Published Date : Aug 28, 2023

Study Type : Human Study

Additional Links

Substances : Astaxanthin, Krill

Diseases : Osteoarthritis

Pharmacological Actions : Osteoprotective

[+]

Genotype may codetermine potential vitamin A side effects on retinal integrity.Jan 31, 2012

Click here to read the entire abstract

Pubmed Data : Ophthalmologe. 2012 Feb ;109(2):112-20. PMID: 22350547

Article Published Date : Jan 31, 2012

Study Type : Human Study

Additional Links

Substances : DHA (Docosahexaenoic Acid), Lutein, Vitamin A

Additional Keywords : Genotype, Ophthalmology, Retina Degeneration, Vitamin A Side Effects

[+]

[+]

Higher concentrations of trans- and cis-lycopene may reduce the time to clearance of an oncogenic HPV infection.May 01, 2003

Click here to read the entire abstract

Pubmed Data : Cancer Causes Control. 2003 May;14(4):319-26. PMID: 12846362

Article Published Date : May 01, 2003

Study Type : Human Study

Additional Links

Substances : Carotenoids, Lycopene

Diseases : Human Papillomavirus (HPV), Uterine Cervical Neoplasms

[+]

Higher intake and serum levels of most carotenoids were associated with lower odds of having NAFLD.May 16, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2019 May 17 ;11(5). Epub 2019 May 17. PMID: 31108934

Article Published Date : May 16, 2019

Study Type : Human Study

Additional Links

Substances : Alpha-Carotene, beta-Carotene, Carotenoids, Cryptoxanthin, Lutein, Zeaxanthin

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

Higher intake of bioavailable lutein and zeaxanthin is associated with a long-term reduced risk of advanced age-related macular degeneration.Oct 07, 2015

Click here to read the entire abstract

Pubmed Data : JAMA Ophthalmol. 2015 Oct 8:1-10. Epub 2015 Oct 8. PMID: 26447482

Article Published Date : Oct 07, 2015

Study Type : Human Study

Additional Links

Substances : Carotenoids, Fruit: All, Lutein, Vegetables: All , Zeaxanthin

Diseases : Macular Degeneration

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2020 Dec 27 ;13(1). Epub 2020 Dec 27. PMID: 33375429

Article Published Date : Dec 26, 2020

Study Type : Human Study

Additional Links

Substances : Astaxanthin, Bacopa, Lycopene, Vitamin B-12

Diseases : Aging: Brain , Brain: Oxidative Stress, Cognitive Decline/Dysfunction

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

In older women, β-carotene levels are independently and inversely associated with estradiol.Jul 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Vitam Nutr Res. 2019 Apr 1:1-8. Epub 2019 Apr 1. PMID: 30932775

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Med Food. 2003;6(1):51-6. PMID: 12804020

Article Published Date : Jan 01, 2003

Study Type : Human Study

Additional Links

Substances : Astaxanthin

[+]

Serum carotenoids are inversely associated with prevalence of NAFLD in middle aged and elderly Chinese.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Pediatr. 2012 Jul ;161(1):58-64.e1-2. Epub 2012 Feb 28. PMID: 22381025

Article Published Date : Jun 30, 2012

Study Type : Human Study

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Substances : beta-Carotene, Fruit: All, Vegetables: All

Diseases : Insulin Resistance, Overweight

Pharmacological Actions : Insulin Sensitizers

Additional Keywords : Anti-Obesity Agents, Fruit Juice, Vegetable Juice

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Supplementation with lutein and zeaxanthin improves CNS xanthophyll levels and cognitive function in healthy adults.Nov 13, 2017

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Pubmed Data : Nutrients. 2017 Nov 14 ;9(11). Epub 2017 Nov 14. PMID: 29135938

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Pubmed Data : Int J Clin Pract. 2021 Jan 14:e14022. Epub 2021 Jan 14. PMID: 33445213

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Pubmed Data : Clin Ophthalmol. 2021 ;15:2293-2300. Epub 2021 Jun 2. PMID: 34113073

Article Published Date : Dec 31, 2020

Study Type : Human Study

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Substances : Crocetin, Hesperidin, Tamarind

Diseases : Glaucoma

Pharmacological Actions : Antioxidants

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Additional Keywords : Risk Reduction

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Pubmed Data : J Affect Disord. 2015 Mar 15 ;174:51-6. Epub 2014 Nov 26. PMID: 25484177

Article Published Date : Mar 14, 2015

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Pubmed Data : Sleep. 2015 Jul 24. Epub 2015 Jul 24. PMID: 26237775

Article Published Date : Jul 23, 2015

Study Type : Human Study

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Substances : Carotenoids, Vitamin C, Vitamin D

Diseases : Inflammation, Oxidative Stress

Pharmacological Actions : Antihypertensive Agents, Antioxidants

Additional Keywords : Risk Factors, Sleep Duration

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This study indicates that higher serum carotenoid levels might be inversely associated with non-Hodgkin lymphoma risk.Apr 29, 2020

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Pubmed Data : Br J Nutr. 2020 Apr 30:1-31. Epub 2020 Apr 30. PMID: 32349798

Article Published Date : Apr 29, 2020

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Pubmed Data : J Hypertens. 2019 Jul 26. Epub 2019 Jul 26. PMID: 31356404

Article Published Date : Jul 25, 2019

Study Type : Human Study

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Substances : Alpha-Carotene, beta-Carotene, Carotenoids, Cryptoxanthin, Lutein, Lycopene, Zeaxanthin

Diseases : Hypertension

Additional Keywords : Risk Reduction

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Vegetables and fruits rich in lycopene and other carotenoids may be protective against prostate cancer.Mar 01, 2005

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Pubmed Data : Int J Cancer. 2005 Mar 1;113(6):1010-4. PMID: 15514967

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Pubmed Data : Eur J Nutr. 2016 Feb ;55(1):171-82. Epub 2015 Jan 17. PMID: 25595100

Article Published Date : Feb 01, 2016

Study Type : Human In Vitro

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Substances : Anthocyanins, Blueberry, Carotenoids, Fiber

Diseases : Atherosclerosis

Pharmacological Actions : Antioxidants

Additional Keywords : Plant Extracts

[+]

Astaxanthin could be useful for improving chronic inflammation such as that associated with oral lichen planus.Apr 30, 2015

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Pubmed Data : Avicenna J Med Biotechnol. 2018 Apr-Jun;10(2):69-74. PMID: 29849982

Article Published Date : Apr 01, 2018

Study Type : Human In Vitro

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Substances : Astaxanthin

Pharmacological Actions : Regenerative

Additional Keywords : Nerve Regeneration

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Enhanced proliferation and differentiation of mesenchymal stem cells by astaxanthin-encapsulated polymeric micelles.Jan 01, 2019

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Pubmed Data : Antioxidants (Basel). 2020 Nov 25 ;9(12). Epub 2020 Nov 25. PMID: 33255669

Article Published Date : Nov 24, 2020

Study Type : Human In Vitro

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Substances : Fucoxanthin

Diseases : Diabetic Retinopathy

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants

[+]

Protective effects of crocetin on arsenic trioxide-induced oxidative stress.Oct 31, 2021

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Pubmed Data : In Vivo. 2021 Nov-Dec;35(6):3157-3163. PMID: 34697146

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Pubmed Data : Planta Med. 2021 Apr ;87(5):368-374. Epub 2020 Oct 29. PMID: 33124008

Article Published Date : Mar 31, 2021

Study Type : Animal Study

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Substances : Achiote, Carotenoids, Vitamin E

Diseases : Aging, Oxidative Stress

Pharmacological Actions : Antioxidants

Additional Keywords : Plant Extracts

[+]

Administration of lutein in combination with vitamin C improved the status of the total antioxidant defense system in SD rats.Aug 31, 2015

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Pubmed Data : Lab Anim Res. 2015 Sep ;31(3):117-24. Epub 2015 Sep 30. PMID: 26472964

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Pubmed Data : Mol Med Rep. 2020 Dec ;22(6):5271-5281. Epub 2020 Oct 14. PMID: 33173984

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Pubmed Data : Med Hypotheses. 2011 Jul 15. Epub 2011 Jul 15. PMID: 21764223

Article Published Date : Jul 15, 2011

Study Type : Animal Study

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Substances : Astaxanthin, Spirulina

Diseases : Fatty Liver

Pharmacological Actions : Hepatoprotective

[+]

Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.Sep 12, 2023

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Pubmed Data : Cochrane Database Syst Rev. 2023 Sep 13 ;9(9):CD000254. Epub 2023 Sep 13. PMID: 37702300

Article Published Date : Sep 12, 2023

Study Type : Animal Study

Additional Links

Substances : beta-Carotene, Vitamin C, Vitamin E, Zinc

Diseases : Macular Degeneration

Pharmacological Actions : Antioxidants

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View the Evidence: 1143 Abstracts with Carotenoids Research

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Astaxanthin influence on health outcomes of adults at risk of metabolic syndrome.May 12, 2022

Dietary intake of carotenoids and risk of depressive symptoms.Nov 06, 2022

This systematic review and meta-analyses suggested that lycopene intake exerted an FBG-decreasing effect.Dec 26, 2022

Vitamin C, vitamin E, β-carotene and risk of Parkinson's disease.Mar 23, 2023

Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers.Dec 29, 2021

Carotenoids supplementation and inflammation.May 16, 2021

Consumption of large amounts of tomato products may be associated with a reduced risk of gastric cancer.Mar 31, 2013

Dietary vitamin and carotenoid intake and risk of age-related cataract.Jan 08, 2019

Higher blood concentrations of lutein are generally associated with better cardiometabolic health.Jan 12, 2016

Higher concentrations of plasma carotenoids may reduce risk of urothelial cell carcinoma (UCC), in particular aggressive UCC.Sep 30, 2012

Higher dietary intakes of selenium, vitamin C, vitamin E, β-carotene and β-cryptoxanthin were associated with reduced pancreatic cancer risk.Jun 29, 2016

Higher intake of vitamin C, carotenoids, and α- tocopherol were associated with reduced risk of cardiovascular disease, total cancer, and all-cause mortality.Oct 31, 2018

Higher vitamin C intake and higher circulating concentrations of vitamin C, vitamin E and β-carotene are associated with a lower risk of CVD mortality.Jan 10, 2019

Supplementation of astaxanthin in the diet has positive effects on symptoms associated with obesity related diseases.May 07, 2021

Systematic review and meta-analysis on the effects of astaxanthin on human skin ageing.Aug 23, 2021

This meta-analysis suggests that blood retinol level is a double-edged sword for risk of hip fracture.Aug 31, 2014

Decreased intake of vegetables and fruits during pregnancy and the consequent decreased intake of nutrients such as folate and lutein/zeaxanthin, necessary for DNA methylation, synthesis, and retinal function, may increase risk for having a child with spJun 01, 2005

The effect of astaxanthin supplementation on performance and fat oxidation during a 40 km cycling time trial Jul 02, 2020

A blackcurrant product regulated the microbiota of volunteers and decreased the activity of βeta glucuronidase.Feb 28, 2014

A combination of nutrients improves age-related macular degeneration. Feb 01, 2008

A combined micronutrient dietary supplement should be considered in the overall management of AD.Sep 08, 2022

A diet rich in linoleic acid containing foods (e.g. white meats and fish) and beta-carotene was inversely related to HCC risk; iron intake was associated with increased risk. Nov 01, 2007

A dietary cholesterol challenge study to assess Chlorella supplementation in maintaining healthy lipid levels.May 12, 2016

A dietary supplement containing astaxanthin and saw palmetto berry extract decrease dihydrotestosterone, increase testosterone and decrease estradiol levels in healthy males. Sep 01, 2009

A formula containing calcium, vitamin D3, lycopene , astaxantin and citrus bioflavonoids reducing climacteric symptoms in menopausal women. Jun 01, 2010

A greater intake of choline and lutein and zeaxanthin was associated with faster performance on a cognitive flexibility task in overweight people.Jan 14, 2021

Additional consumption of one egg per day increases serum lutein plus zeaxanthin concentration and lowers oxidized low-density lipoprotein.Aug 31, 2017

Alcohol consumption decreases the protection efficiency of the antioxidant network and increases the risk of sunburn in human skin.Dec 31, 2012

An antioxidant formula increases important fat-soluble nutrients and antioxidants and reduces airway inflammation in patients with Cystic Fibrosis. Jan 01, 2008

Annatto carotenoids attenuate oxidative stress and inflammatory response after high-calorie meal in healthy subjects.Jan 09, 2017

Antioxidant supplementation may have therapeutic value in the treatment of cystic fibrosis - Article 2. Jan 01, 2003

Antioxidant supplements prevent oxidation of cysteine/cystine redox in patients with age-related macular degeneration.Dec 01, 2005

Astaxanthin addition improves human neutrophils function.Dec 01, 2010

Astaxanthin ameliorates inflammation, oxidative stress, and reproductive outcomes in endometriosis patients.Dec 31, 2022

Astaxanthin and sesamin supplementation may be a candidate to promote recovery from mental fatigue.Feb 27, 2018

Astaxanthin appears to be an effective agent to increase endogenous antioxidant status.Oct 04, 2021

Astaxanthin derived from Haematococcus pluvialis improves the skin condition in both women and men.Mar 17, 2012

Astaxanthin has a positive effect on lipid profiles and oxidative stress in overweight subjects. Oct 01, 2011

Astaxanthin has antioxidant properties in soccer players.Nov 27, 2012

Astaxanthin improves glucose metabolism and reduces blood pressure in patients with type 2 diabetes mellitus.Dec 31, 2017

Astaxanthin improves human sperm capacitation by inducing lyn displacement and activation.Aug 24, 2015

Astaxanthin improves oxidative stress in overweight and obese adults. Apr 08, 2011

Astaxanthin increases blood flow in the eyes as measured by increased choroidal blood flow velocity.Nov 10, 2011

Astaxanthin prevents in vitro auto-oxidative injury in human lymphocytes.Oct 01, 2010

Astaxanthin protects smokers against oxidative stress. Sep 01, 2011

Astaxanthin reduces heart rate and carbohydrate oxidation rates during exercise in overweight individuals.Dec 31, 2022

Astaxanthin reduces reflux symptoms in patients, especially in those with pronounced H. pylori infection.Jun 01, 2008

Astaxanthin seems protective against UV-induced skin deterioration and helps maintain healthy skin in healthy people.Jun 24, 2018

Astaxanthin significantly improves athletic performance as measured by cycling time. Oct 07, 2011

Astaxanthin supplementation counters exercise-induced decreases in immune-related plasma proteins.Dec 31, 2022

Astaxanthin supplementation enhances metabolic adaptation with aerobic training in the elderly.May 31, 2021

Astaxanthin supplementation impact on insulin resistance, lipid profile, blood pressure, and oxidative stress in polycystic ovary syndrome patients.Oct 23, 2023

Astaxanthin supplementation improves sIgA response and attenuates muscle damage, thus preventing inflammation induced by rigorous physical training.Dec 31, 2014

Astaxanthin supplementation may have a beneficial effect on muscle damage and oxidative stress markers in atheletes. Jul 31, 2012

Astaxanthin supplementation play a beneficial role in reducing some components of lipid profile levels.Dec 31, 2022

Astaxanthin supplementation reduces lipid peroxidation. Jan 01, 2007

Astaxanthin supplementation results in measurable improvement in the antioxidant status of human subjects. Jan 01, 2011

Astaxanthin supplemented with high-intensity functional training decreases adipokines levels and cardiovascular risk factors in men with obesity.Jan 05, 2023

Astaxanthin treatment ameliorates ER stress in polycystic ovary syndrome patients.Feb 27, 2023

Astaxanthin treatment has been shown to increase both serum TAC levels and activation of the Nrf2 axis in PCOS patients' GCs.Mar 02, 2022

Astaxanthin, a natural antioxidant, lowers cholesterol and markers of cardiovascular risk in individuals with prediabetes and dyslipidaemia.Jun 30, 2023

Astaxanthin, β-carotene, and resveratrol-rich foods support resistance training-induced adaptation.Jan 13, 2021

Astaxanthin-rich Haematococcus pluvialis extract improves cognitive function in the healthy aged individuals.Aug 31, 2012

Benefits and safety of astaxanthin in the treatment of mild-to-moderate dry eye disease.Dec 31, 2020

Beta-carotene has therapeutic value in the treatment of leukoplakias.Dec 01, 1999

Beta-carotene supplementation ameliorates deficiencies and reduces oxidative stress in Cystic Fibrosis patients. Jan 01, 2000

Beta-carotene, vitamin C and vitamin E deficiencies may play a role in the pathogenesis of thyroid cancer. Jun 01, 1997

Bioavailability Study: Administration After-Meal Significantly Improves Availability. Sep 01, 2009

Breast cancer risk may be affected by telomere length among premenopausal women or women with low dietary intake of antioxidants or antioxidant supplements. Apr 01, 2009

Carotenoids such as lycopene have a protective effect on bone health.Jun 01, 2009

Carotenoids, Vitamin C and E, reduce the risk of cataracts in women. Jan 01, 2008

Co-consuming cooked whole eggs is an effective way to enhance carotenoid absorption from other carotenoid-rich foods.May 26, 2015

Carotenoids

View the Evidence:
1143 Abstracts with Carotenoids Research