Carotenoids

Name	AC	CK
Oxidative Stress	106	289
Breast Cancer	27	165
Macular Degeneration	21	156
Cognitive Decline/Dysfunction	18	138
Inflammation	37	107
Alzheimer's Disease	29	94
Nonalcoholic fatty liver disease (NAFLD)	12	87
Cataract	14	85
Breast Cancer: Prevention	5	82
Cardiovascular Diseases	20	82
DNA damage	16	82
Hypertension	10	75
Obesity	18	67
Gastric Cancer	7	54
Diabetes Mellitus: Type 2	14	52
Kidney Cancer	2	50
Lipid Peroxidation	18	49
Lung Cancer	11	49
Radiation Induced Illness	5	47
Aging: Brain	5	45
Ultraviolet Radiation Induced Damage	16	45
Athletic Performance	6	44
Cancers: All	26	43
Depression	9	42
Prostate Cancer	13	42
Coronary Artery Disease	4	41
Endometrial Cancer	3	40
Prostate Cancer: Prevention	1	40
Memory Disorders	7	39
Insulin Resistance	10	34
C-Reactive Protein	4	32
Overweight	4	32
Pancreatic Cancer	3	32
Smoking	4	31
Atherosclerosis	10	30
Cystic Fibrosis	3	30
Non-Hodgkin Lymphoma	1	30
Vision Disorders	2	30
Vision Loss	2	30
Alcohol Toxicity	12	29
Colon Cancer	11	29
Eye Diseases	6	28
Diabetic Retinopathy	14	26
Helicobacter Pylori Infection	12	25
Immune Disorders: Low Immune Function	4	25
Stroke	3	25
Vitamin A Deficiency	4	25
Dementia	4	24
Diabetic Complications	12	24
Human Papillomavirus (HPV)	4	23
Osteoporosis	4	23
High Homocysteine	3	22
Learning disorders	2	22
Lipopolysaccharide-Induced Toxicity	14	22
Muscle Damage: Exercise-Induced	3	22
Parkinson's Disease	14	22
Aging Skin	3	21
Diabetes Mellitus: Type 1	5	21
All-Cause Mortality	1	20
Bladder Cancer: Prevention	1	20
Bone Fractures	1	20
Cancer Mortality	1	20
Cardiac Mortality	1	20
Gastric Cancer: Prevention	1	20
High Fat Diet	10	20
Hypercholesterolemia	1	20
Liver Cancer	14	20
Metabolic Diseases	1	20
Retinoblastoma	1	20
Visual Display Terminal Eye Fatigue	1	20
Glaucoma	6	19
Liver Cancer: Prevention	4	19
Brain Inflammation	11	18
Cervical Cancer	7	17
Infertility: Male	5	17
Lung Cancer: Prevention	2	16
Metabolic Syndrome X	4	16
Neurodegenerative Diseases	14	16
Sunburn	3	16
Aging	9	15
Diabetic Nephropathy	9	15
Periodontitis	4	15
Cerebral Ischemia	8	14
Kidney Damage	8	14
Myopia	3	14
Sleep Disorders	2	14
Atopic Dermatitis	7	13
Chemotherapy-Induced Toxicity: Cisplatin	7	13
Colorectal Cancer	9	13
Cancers: Multi-Drug Resistant	7	12
Erythema	2	12
Glioblastoma	6	12
Heart Failure	2	12
Liver Fibrosis	8	12
Retinal Diseases	2	12
Uterine Cervical Neoplasms	2	12
Acid Reflux	2	11
Brain: Oxidative Stress	6	11
Hearing Loss	2	11
Photooxidative Stress	5	11
Rheumatoid Arthritis	2	11
AST: Elevated	1	10
Alcoholic Liver Disease	5	10
Apolipoprotein A/B ratio imbalances	1	10
Bladder Cancer	1	10
Cervical Dysplasia	1	10
Chemotherapy and Radiation Toxicity	4	10
Cholesterol: LDL/HDL ratio	1	10
Clostridium Infections	1	10
Colon Cancer: Prevention	1	10
Common variable immunodeficiency (CVID)	1	10
Computer display light exposure	1	10
Creatine Phosphokinase (CK): Elevated	1	10
Diabetes Insipidus	1	10
Diabetes Mellitus: Type 2: Prevention	1	10
Diabetes: Oxidative Stress	5	10
Eye Diseases: Lack of Blood Circuation	1	10
Fatty Liver	6	10
Infant Nutrition	1	10
Leukoplakia	1	10
Low Testosterone	1	10
Male Hormone Imbalances	1	10
Menopausal Syndrome	1	10
Mental Fatigue	1	10
Periodontal Wound Healing	1	10
Phthalate Toxicity	1	10
Pneumonia	1	10
Spinal Cord Injuries	5	10
Testosterone: Too Low	1	10
Thyroid Cancer	1	10
Visual Fatigue	1	10
Brain Injury: Traumatic	5	9
High Fructose Diet	4	9
Oral Cancer	4	9
Burns	4	8
Cardiac Hypertrophy	3	8
Chemically-Induced Liver Damage	4	8
Eye Damage	3	8
Ischemia	4	8
Liver Damage	6	8
Muscle Atrophy	4	8
Wound Healing	5	8
Asthma	5	7
Esophageal Cancer	6	7
Fructose-Induced Toxicity	3	7
Kidney Fibrosis	4	7
Lung Injury: Acute	4	7
Myocardial Fibrosis	2	7
Sepsis	4	7
Subarachnoid hemorrhage	4	7
Chemotherapy-Induced Toxicity: Cyclophosphamide	3	6
Gastric Ulcer	3	6
Hydrogen Peroxide Induced Toxicity	6	6
Hyperglycemia	3	6
Hypoxia	4	6
Liver Damage: Drug-Induced	3	6
Mitochondrial Dysfunction	4	6
Myocardial Ischemia	4	6
Polycystic Ovary Syndrome	3	6
Retinitis Pigmentosa	2	6
Skin Cancer: Prevention	1	6
Squamous cell carcinoma	2	6
Xenobiotic Exposures	2	6
Advanced Glycation Endproduct (AGE) Formation	1	5
Air Pollution Linked Toxicity	3	5
Arthritis	3	5
Breast Cancer: Triple Negative	3	5
Cancers: Drug Resistant	4	5
Drug Toxicity: Methotrexate	3	5
Endothelial Dysfunction	3	5
Neutrophils: Damaged	1	5
Oral Lichen Planus	1	5
Skin Cancer	2	5
Acetaminophen (Tylenol) Toxicity	2	4
Arsenic Poisoning	2	4
Autoimmune Diseases	1	4
Cancer Metastasis	3	4
Chemotherapy-Induced Toxicity: Doxorubicin	2	4
Cholesterol: Oxidation	2	4
Colitis	2	4
Delayed Sleep Phase Disorder	1	4
Diabetes: Cardiovascular Illness	2	4
Drug-Induced Toxicity: Methotrexate	2	4
Dyslipidemias	2	4
Epilepsy	2	4
Insomnia	1	4
Kidney Damage: Chemically-Induced	2	4
Leukemia	2	4
Liver Injury: Ischemia/reperfusion	2	4
Low Immune Function: Splenic Dysfunction	1	4
Lung Damage	2	4
Lymphadenopathy	1	4
Lymphoma	1	4
Maculopathy: Age-Related	1	4
Melanoma	2	4
Middle Cerebral Artery Occlusion (MCAO)	2	4
Multiple Sclerosis	2	4
Myocardial Infarction	2	4
Osteoarthritis	3	4
Pancreatitis	2	4
Photokeratitis	2	4
Proteinuria	1	4
Retinal Degeneration: Light-Induced	2	4
Stress	2	4
Stroke: Prevention	2	4
Testicular Injury: Chemical/Metal Induced	2	4
Tongue Cancer	1	4
Tracheal Cancer	1	4
Traumatic Brain Injury	2	4
Blue Light Toxicity	2	3
Carcinoma: Non-Small-Cell Lung	3	3
Chronic Kidney Disease (CKD)	2	3
Coronavirus Infection	3	3
Diabetes: Cognitive Dysfunction	2	3
Fibrosis	2	3
Homocysteine: Elevated	2	3
Iron Overload	1	3
Iron Poisoning	1	3
Leukemia: Acute promyelocytic leukemia	2	3
Pre-Eclampsia	2	3
Skin Diseases: Photo-Aging	2	3
Aflatoxicosis	1	2
Agent Orange Toxicity	1	2
Aging: Heart	1	2
Allergic Airway Diseases	1	2
Aluminum Toxicity	1	2
Arterial Hardening: Elasticity	1	2
Aspirin-Induced Toxicity	1	2
Benzo[a]pyrene-induced Toxicity	1	2
Bisphenol Toxicity	1	2
Bladder Outlet Obstruction	1	2
Blindness	1	2
Blood Pressure: High	1	2
Brain Ischemia	1	2
Breast Cancer: Chemically-Induced	1	2
Cachexia	1	2
Cadmium Poisoning	1	2
Cancer Stem Cells	2	2
Cardiomegaly	1	2
Cardiomyopathy	1	2
Chemotherapy-Induced Toxicity: Arsenic Trioxide	1	2
Chemotherapy-Induced Toxicity: Gentamicin	1	2
Chemotherapy-Induced Toxicity: Kidney	1	2
Chronic Obstructive Pulmonary Disease	1	2
Chronic Pain	1	2
Coenzyme Q10 Deficiency	1	2
Cough	1	2
Dengue	1	2
Dental Caries	1	2
Dental Diseases	1	2
Diabetes: Cataract	1	2
Diabetes: Dental Problems	1	2
Diabetes: Immune Problems	1	2
Diabetes: Low Immune Function	1	2
Drug-Induced Toxicity: Indomethacin	1	2
Dry Eye Syndromes	2	2
Dysbiosis	1	2
Exercise-Induced Tissue Damage	1	2
Fibrosarcoma	1	2
Fulminant Hepatic Failure	1	2
Gastrointestinal Inflammation	1	2
Gestational Diabetes	1	2
Hepatic Steatosis	1	2
High Cholesterol	1	2
High Sugar Diet	1	2
Hyperhomocysteinemia	1	2
Hyperuricemia	1	2
Hypothyroidism	1	2
Immune Dysregulation: TH1 dominance	1	2
Infertility: Female	1	2
Intestinal Injury	1	2
Intima Media Thickening	1	2
Intraocular hypertension	1	2
Keratitis	1	2
Kidney Damage: Drug-Induced	1	2
Kidney Diseases	1	2
Liver Cirrhosis	1	2
Liver Damage: Aflatoxin-Induced	1	2
Low Libido	1	2
Mastocytoma	1	2
Memory Loss	1	2
Mercury Poisoning	1	2
Miscarriage	1	2
Necrotising enterocolitis	1	2
Neuropathic Pain	1	2
Obsessive-Compulsive Disorder	1	2
Osteopenia	1	2
Ovarian Cancer	2	2
Periodontal Diseases	1	2
Pesticide Toxicity	1	2
Pregnancy Complications	1	2
Prenatal Chemical Exposures	1	2
Prostatic Hyperplasia: Benign	1	2
Pruritus	1	2
Pulmonary Fibrosis: Bleomycin-Induced	1	2
Radiation Induced Illness: Bone Marrow	1	2
Retinal Detachment	1	2
Retinopathy: Hyperoxia-induced	1	2
Seizures	1	2
Skin Diseases	2	2
Sperm Quality: Low	1	2
Spinal Cord Inflammation	1	2
Stroke: Ischemic	1	2
Thrombosis	1	2
Tobacco Toxicity	1	2
Triglycerides: Elevated	1	2
Ulcerative Colitis	1	2
Uveitis	1	2
Vascular Dementia	1	2
Weight Problems	1	2
Advanced Glycation End products (AGE)	1	1
Alzheimer's Disease: Homocysteine Associated	1	1
Autism	1	1
Cancers	1	1
Cardiac Failure	1	1
Central Nervous System Diseases	1	1
Chronic Disease	1	1
Copper Toxicity	1	1
Corticosteroid-Induced Toxicity	1	1
Deoxynivalenol Induced Toxicity	1	1
Dopamine Toxicity	1	1
Dry Skin	1	1
Endometritis	1	1
Endothelial Damage	1	1
Gastrointestinal Diseases	1	1
Glioma	1	1
Glomerulosclerosis	1	1
Hepatitis C	1	1
Hepatoma	1	1
Hyperlipidemia	1	1
Inflammatory Bowel Diseases	1	1
Lead Poisoning	1	1
Liver Disease	1	1
Liver Diseases	1	1
Lung Diseases	1	1
Mitochondrial Diseases	1	1
Nasopharyngeal Cancer	1	1
Neuroblastoma	1	1
Neurological Conditions	1	1
Neurotoxicity	1	1
Promyelocytic leukemia	1	1
Pseudomonas aeruginosa	1	1
Pulmonary Fibrosis	1	1
Radiation	1	1
Sickle Cell Anemia	1	1
Staphylococcus aureus infection	1	1
Staphylococcus epidermidis	1	1
Streptococcus pyogenes	1	1
Tumors	1	1
Vascular Calcification	1	1
Zinc Deficiency	1	1

Name	AC	CK
Antioxidants	306	981
Chemopreventive	51	423
Neuroprotective Agents	112	383
Anti-Inflammatory Agents	149	319
Hepatoprotective	39	127
Cardioprotective	40	124
Interleukin-6 Downregulation	42	108
Anticarcinogenic Agents	26	105
Apoptotic	53	95
Tumor Necrosis Factor (TNF) Alpha Inhibitor	41	92
Anti-Apoptotic	49	82
Interleukin-1 beta downregulation	38	79
Antiproliferative	53	78
Nrf2 activation	44	76
NF-kappaB Inhibitor	37	74
Photoprotective	18	56
Heme oxygenase-1 up-regulation	26	44
Antihypertensive Agents	9	41
Malondialdehyde Down-regulation	12	41
Superoxide Dismutase Up-regulation	13	41
Antidepressive Agents	7	38
Renoprotective	20	36
Hypolipidemic	16	35
Cyclooxygenase 2 Inhibitors	18	30
Telomere Protective	2	30
Immunomodulatory	14	29
Regenerative	6	27
Chemosensitizer	16	26
Anti-Fibrotic	13	25
Cytoprotective	10	24
MicroRNA modulator	9	24
Radioprotective	10	24
Antineoplastic Agents	9	23
Anti-metastatic	15	22
Cell cycle arrest	15	21
Hypoglycemic Agents	7	21
Immunostimulatory	5	20
Chemoprotective Agents	10	19
Insulin Sensitizers	5	17
Anti-atherogenic	4	15
Chemotherapeutic	13	15
Osteoprotective	4	15
Gastrointestinal Agents	8	14
Gastroprotective	7	13
Interferon Gamma Reducer	3	13
Enzyme Inhibitors	3	12
Malonaldehyde (MDA) Down-Regulation	2	12
Catalase Up-Regulation	5	11
Adiponectin upregulation	1	10
Aromatase Inhibitors	1	10
Ergogenic	1	10
Genoprotective	4	10
Isoprostane Down-Regulation	1	10
Interleukin-4 downregulation	4	8
Bcl-2 protein down-regulation	5	7
Brain-derived neurotrophic factor modulator	3	7
Interleukin-8 downregulation	5	7
Anti-Bacterial Agents	5	6
Autophagy Up-regulation	5	6
Detoxifier	2	6
Glutathione Upregulation	3	6
Prophylactic Agents	3	6
Tumor Suppressor Protein p53 Upregulation	4	6
Angiogenesis Inhibitors	3	5
Interleukin-5 downregulation	3	5
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	3	5
Matrix metalloproteinase-9 (MMP-9) inhibitor	3	5
Vascular Endothelial Growth Factor Inhibitors	3	5
Anti-Asthmatic Agents	2	4
Glutathione Peroxidase 1 (GPx1) Up-Regulation	2	4
Hypotensive	2	4
Matrix metalloproteinase-1 (MMP-1) inhibitor	3	4
Nitric Oxide Inhibitor	2	4
Pancreato Protective Agents	2	4
Radiosensitizer	3	4
STAT3 Inhibitor	3	4
Anti-Proliferative	1	3
Fertility Agents: Male	2	3
Interleukin-1 alpha downregulation	1	3
Matrix metalloproteinase-3 (MMP-3) inhibitor	2	3
Multidrug Resistance Gene Modulators	2	3
P21 Activation	3	3
Vasodilator Agents	2	3
Acetylcholinesterase Inhibitor	1	2
Angiotensin-Converting Enzyme Inhibitors	1	2
Anti-Adipogenic	1	2
Anti-Angiogenic	2	2
Anti-Ulcer Agents	1	2
Anti-thrombotic	1	2
Anticholesteremic Agents	1	2
Antinoceceptive	1	2
Antioxidant	1	2
Antitussive Agents	1	2
Anxiolytic	1	2
Aphrodisiac	1	2
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	2	2
Interferon-gamma (IFN-gamma) inducer	1	2
Interleukin-10 upregulation	1	2
Lipoxygenase Inhibitors	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	2
Neuritogenic	1	2
Neurogenesis	1	2
P-glycoprotein Inhibitors	1	2
Postaglandin PGE2 downregulation	1	2
Redox Balancer	1	2
Uricosuric Agents	1	2
Vascular Endothelial Growth Factor C Inhibitor	1	2
Xanthine oxidase inhibitor	1	2
apoptosis	1	2
5-alpha reductase inhibitor	1	1
Antimicrobial	1	1
Antimutagenic Agents	1	1
Antiviral Agents	1	1
Bax/Bcl2 ratio: Increase	1	1
Caspase-3 Activation	1	1
Cyclin D1 Down-Regulation	1	1
Cytotoxic	1	1
Erk/MAP Inactivation	1	1
Histone deacetylase inhibitor	1	1
Interleukin-12 downregulation	1	1
Nitric Oxide Enhancer	1	1
P38 Mitogen-Activated Protein Kinase Modulator	1	1
Prostaglandin PGE2 downregulation	1	1
Receptor activator of NF-κB (RANK) gene expression	1	1
Transforming growth factor beta (TGF-β) inhibitor	1	1
Wnt/β-catenin pathway down-regulation	1	1
Wnt/β-catenin signaling pathway modulation	1	1
interleukin-13 down-regulation	1	1

[+]

Astaxanthin influence on health outcomes of adults at risk of metabolic syndrome.May 12, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

A combination of nutrients improves age-related macular degeneration. Feb 01, 2008

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Pubmed Data : Food Res Int. 2017 Sep ;99(Pt 2):944-949. Epub 2017 Mar 4. PMID: 28847431

Article Published Date : Aug 31, 2017

Study Type : Human Study

Additional Links

Substances : Egg, Lutein, Zeaxanthin

Diseases : Hypercholesterolemia

Pharmacological Actions : Malondialdehyde Down-regulation

[+]

Alcohol consumption decreases the protection efficiency of the antioxidant network and increases the risk of sunburn in human skin.Dec 31, 2012

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Pubmed Data : Skin Pharmacol Physiol. 2013 ;26(1):45-51. Epub 2012 Nov 7. PMID: 23147451

Article Published Date : Dec 31, 2012

Study Type : Human Study

Additional Links

Substances : Carotenoids

Diseases : Alcohol Toxicity , Sunburn

Therapeutic Actions : Sunlight exposure

Additional Keywords : Plant Extracts

Problem Substances : Alcohol Consumption

[+]

An antioxidant formula increases important fat-soluble nutrients and antioxidants and reduces airway inflammation in patients with Cystic Fibrosis. Jan 01, 2008

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Pubmed Data : J Cyst Fibros. 2008 Jan;7(1):60-7. Epub 2007 Jun 13. PMID: 17569601

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Antioxidant formulas, Carotenoids, Coenzyme Q10, Vitamin E

Diseases : Cystic Fibrosis

Pharmacological Actions : Antioxidants

[+]

Annatto carotenoids attenuate oxidative stress and inflammatory response after high-calorie meal in healthy subjects.Jan 09, 2017

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Pubmed Data : Food Res Int. 2017 10 ;100(Pt 1):771-779. Epub 2017 Aug 3. PMID: 28873749

Article Published Date : Jan 09, 2017

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Pubmed Data : Eur J Nutr. 2010 Dec;49(8):447-57. Epub 2010 Apr 2. PMID: 20361333

Article Published Date : Dec 01, 2010

Study Type : Human Study

Additional Links

Substances : Astaxanthin

Diseases : Immune Disorders: Low Immune Function, Oxidative Stress

Pharmacological Actions : Antioxidants, Immunostimulatory, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Astaxanthin and sesamin supplementation may be a candidate to promote recovery from mental fatigue.Feb 27, 2018

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Pubmed Data : Nutrients. 2018 Feb 28 ;10(3). Epub 2018 Feb 28. PMID: 29495607

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Pubmed Data : Phytother Res. 2012 Nov 28. Epub 2012 Nov 28. PMID: 23192897

Article Published Date : Nov 27, 2012

Study Type : Human Study

Additional Links

Substances : Astaxanthin

Diseases : Athletic Performance, Oxidative Stress

Pharmacological Actions : Antioxidants

[+]

Astaxanthin improves glucose metabolism and reduces blood pressure in patients with type 2 diabetes mellitus.Dec 31, 2017

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Pubmed Data : J Med Food. 2011 Sep 1. Epub 2011 Sep 1. PMID: 21883001

Article Published Date : Sep 01, 2011

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Pubmed Data : Int J Sports Med. 2011 Oct 7. Epub 2011 Oct 7. PMID: 21984399

Article Published Date : Oct 07, 2011

Study Type : Human Study

Additional Links

Substances : Astaxanthin

Diseases : Athletic Performance

Pharmacological Actions : Ergogenic

[+]

Astaxanthin supplementation enhances metabolic adaptation with aerobic training in the elderly.May 31, 2021

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Pubmed Data : Physiol Rep. 2021 Jun ;9(11):e14887. PMID: 34110707

Pubmed Data : Cancer. 1997 Jun 1;79(11):2186-92. PMID: 9179066

Article Published Date : Jun 01, 1997

Study Type : Human Study

Additional Links

Substances : beta-Carotene, Vitamin C, Vitamin E

Diseases : Thyroid Cancer

[+]

Bioavailability Study: Administration After-Meal Significantly Improves Availability. Sep 01, 2009

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Pubmed Data : Biosci Biotechnol Biochem. 2009 Sep;73(9):1928-32. Epub 2009 Sep 7. PMID: 19734684

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Substances : Astaxanthin

Additional Keywords : Plant Extracts

[+]

Breast cancer risk may be affected by telomere length among premenopausal women or women with low dietary intake of antioxidants or antioxidant supplements. Apr 01, 2009

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Pubmed Data : Int J Cancer. 2009 Apr 1;124(7):1637-43. PMID: 19089916

Article Published Date : Apr 01, 2009

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Pubmed Data : J Clin Biochem Nutr. 2020 Nov ;67(3):307-316. Epub 2020 Jun 19. PMID: 33293773

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Pubmed Data : Food Funct. 2019 Nov 1 ;10(11):7461-7475. Epub 2019 Oct 31. PMID: 31667483

Article Published Date : Oct 31, 2019

Study Type : Human Study

Additional Links

Substances : Crocetin

Diseases : Atherosclerosis, Coronary Artery Disease

Pharmacological Actions : Anti-atherogenic

[+]

Crocetin may have a suppressive effect on myopia progression in children.Aug 06, 2019

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Pubmed Data : Am J Clin Nutr. 2009 Nov;90(5):1402-10. Epub 2009 Sep 30. PMID: 19793852

Article Published Date : Nov 01, 2009

Study Type : Human Study

Additional Links

Substances : beta-Carotene, Carotenoids, Lutein, Vitamin C, Vitamin E, Zeaxanthin

Diseases : DNA damage, Radiation Induced Illness

Pharmacological Actions : Antioxidants

[+]

High intake of carotenoid-rich food may play a role in protecting telomeres and regulating telomere length.Jan 26, 2016

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Pubmed Data : Eur J Nutr. 2016 Jan 27. Epub 2016 Jan 27. PMID: 26818530

Article Published Date : Jan 26, 2016

Study Type : Human Study

Additional Links

Substances : Carotenoids

Pharmacological Actions : Telomere Protective

[+]

High intakes of vitamin A, retinol, and provitamin A carotenoids may reduce the risk of gastric cancer.Feb 01, 2007

Higher intakes of β-carotene, β-cryptoxanthin, and folate, whether total or from diet, are associated with lower risk of hearing loss.Sep 08, 2015

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Pubmed Data : Am J Clin Nutr. 2015 Sep 9. Epub 2015 Sep 9. PMID: 26354537

Article Published Date : Sep 08, 2015

Study Type : Human Study

Additional Links

Substances : Carotenoids, Cryptoxanthin, Folate, Vitamin A, Vitamin E

Diseases : Hearing Loss

Additional Keywords : Risk Reduction

[+]

Higher lutein and zeaxanthin intake during pregnancy was associated with better offspring verbal intelligence and behaviour regulation in mid-childhood.Jan 19, 2021

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Pubmed Data : J Nutr. 2021 Jan 20. Epub 2021 Jan 20. PMID: 33484136

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Pubmed Data : Int J Vitam Nutr Res. 2019 Apr 1:1-8. Epub 2019 Apr 1. PMID: 30932775

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Pubmed Data : J Med Food. 2003;6(1):51-6. PMID: 12804020

Article Published Date : Jan 01, 2003

Study Type : Human Study

Additional Links

Substances : Astaxanthin

[+]

Serum carotenoids are inversely associated with prevalence of NAFLD in middle aged and elderly Chinese.Dec 31, 2014

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Pubmed Data : J Pediatr. 2012 Jul ;161(1):58-64.e1-2. Epub 2012 Feb 28. PMID: 22381025

Article Published Date : Jun 30, 2012

Study Type : Human Study

Additional Links

Substances : beta-Carotene, Fruit: All, Vegetables: All

Diseases : Insulin Resistance, Overweight

Pharmacological Actions : Insulin Sensitizers

Additional Keywords : Anti-Obesity Agents, Fruit Juice, Vegetable Juice

[+]

Supplementation with lutein and zeaxanthin improves CNS xanthophyll levels and cognitive function in healthy adults.Nov 13, 2017

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Pubmed Data : Nutrients. 2017 Nov 14 ;9(11). Epub 2017 Nov 14. PMID: 29135938

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Pubmed Data : Int J Clin Pract. 2021 Jan 14:e14022. Epub 2021 Jan 14. PMID: 33445213

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Pubmed Data : Clin Ophthalmol. 2021 ;15:2293-2300. Epub 2021 Jun 2. PMID: 34113073

Article Published Date : Dec 31, 2020

Study Type : Human Study

Additional Links

Substances : Crocetin, Hesperidin, Tamarind

Diseases : Glaucoma

Pharmacological Actions : Antioxidants

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Additional Keywords : Risk Reduction

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Pubmed Data : J Affect Disord. 2015 Mar 15 ;174:51-6. Epub 2014 Nov 26. PMID: 25484177

Article Published Date : Mar 14, 2015

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Pubmed Data : Sleep. 2015 Jul 24. Epub 2015 Jul 24. PMID: 26237775

Article Published Date : Jul 23, 2015

Study Type : Human Study

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Substances : Carotenoids, Vitamin C, Vitamin D

Diseases : Inflammation, Oxidative Stress

Pharmacological Actions : Antihypertensive Agents, Antioxidants

Additional Keywords : Risk Factors, Sleep Duration

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This study indicates that higher serum carotenoid levels might be inversely associated with non-Hodgkin lymphoma risk.Apr 29, 2020

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Pubmed Data : Br J Nutr. 2020 Apr 30:1-31. Epub 2020 Apr 30. PMID: 32349798

Article Published Date : Apr 29, 2020

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Pubmed Data : J Hypertens. 2019 Jul 26. Epub 2019 Jul 26. PMID: 31356404

Article Published Date : Jul 25, 2019

Study Type : Human Study

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Substances : Alpha-Carotene, beta-Carotene, Carotenoids, Cryptoxanthin, Lutein, Lycopene, Zeaxanthin

Diseases : Hypertension

Additional Keywords : Risk Reduction

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Vegetables and fruits rich in lycopene and other carotenoids may be protective against prostate cancer.Mar 01, 2005

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Pubmed Data : Int J Cancer. 2005 Mar 1;113(6):1010-4. PMID: 15514967

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Pubmed Data : Eur J Nutr. 2016 Feb ;55(1):171-82. Epub 2015 Jan 17. PMID: 25595100

Article Published Date : Feb 01, 2016

Study Type : Human In Vitro

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Substances : Anthocyanins, Blueberry, Carotenoids, Fiber

Diseases : Atherosclerosis

Pharmacological Actions : Antioxidants

Additional Keywords : Plant Extracts

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Astaxanthin could be useful for improving chronic inflammation such as that associated with oral lichen planus.Apr 30, 2015

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Pubmed Data : Avicenna J Med Biotechnol. 2018 Apr-Jun;10(2):69-74. PMID: 29849982

Article Published Date : Apr 01, 2018

Study Type : Human In Vitro

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Substances : Astaxanthin

Pharmacological Actions : Regenerative

Additional Keywords : Nerve Regeneration

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Enhanced proliferation and differentiation of mesenchymal stem cells by astaxanthin-encapsulated polymeric micelles.Jan 01, 2019

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Pubmed Data : Antioxidants (Basel). 2020 Nov 25 ;9(12). Epub 2020 Nov 25. PMID: 33255669

Article Published Date : Nov 24, 2020

Study Type : Human In Vitro

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Substances : Fucoxanthin

Diseases : Diabetic Retinopathy

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants

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Protective effects of crocetin on arsenic trioxide-induced oxidative stress.Oct 31, 2021

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Pubmed Data : In Vivo. 2021 Nov-Dec;35(6):3157-3163. PMID: 34697146

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A combination of flaxseed oil and astaxanthin may reduce NAFLD by reversing hepatic steatosis and reducing lipid accumulation and oxidative stress.Mar 12, 2017

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Pubmed Data : Nutrients. 2017 Mar 13 ;9(3). Epub 2017 Mar 13. PMID: 28335388

Article Published Date : Mar 12, 2017

Study Type : Animal Study

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Substances : Astaxanthin, Flaxseed Oil

Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD), Oxidative Stress

Pharmacological Actions : Antioxidants, Hepatoprotective, Hypolipidemic

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A variety of carotenoids induce reduce resistance to chemotherapy in multidrug resistant lymphoma and human breast cancer cell lines. Mar 01, 2004

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Pubmed Data : In Vivo. 2004 Mar-Apr;18(2):237-44. PMID: 15113052

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Pubmed Data : Planta Med. 2021 Apr ;87(5):368-374. Epub 2020 Oct 29. PMID: 33124008

Article Published Date : Mar 31, 2021

Study Type : Animal Study

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Substances : Achiote, Carotenoids, Vitamin E

Diseases : Aging, Oxidative Stress

Pharmacological Actions : Antioxidants

Additional Keywords : Plant Extracts

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Administration of lutein in combination with vitamin C improved the status of the total antioxidant defense system in SD rats.Aug 31, 2015

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Pubmed Data : Lab Anim Res. 2015 Sep ;31(3):117-24. Epub 2015 Sep 30. PMID: 26472964

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Pubmed Data : Mol Med Rep. 2020 Dec ;22(6):5271-5281. Epub 2020 Oct 14. PMID: 33173984

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Pubmed Data : ACS Appl Mater Interfaces. 2022 Sep 12. Epub 2022 Sep 12. PMID: 36094079

Astaxanthin ameliorates lipopolysaccharide-induced acute lung injury.Oct 23, 2022

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Pubmed Data : Food Funct. 2022 Oct 24. Epub 2022 Oct 24. PMID: 36278420

Article Published Date : Oct 23, 2022

Study Type : Animal Study

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Substances : Astaxanthin

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Damage

Pharmacological Actions : Anti-Inflammatory Agents, STAT3 Activation

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Astaxanthin ameliorates lipopolysaccharide-induced neuroinflammation, oxidative stress and memory dysfunction.Feb 17, 2019

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Pubmed Data : Behav Pharmacol. 2022 Oct 1 ;33(7):505-512. Epub 2022 Sep 14. PMID: 36148838

Article Published Date : Sep 30, 2022

Study Type : Animal Study

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Substances : Astaxanthin

Diseases : Spinal Cord Injuries

Pharmacological Actions : Antioxidants, Neuroprotective Agents

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Astaxanthin ameliorates the behavioural deficits of prenatal maternal LPS-exposure.Dec 31, 2015

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Pubmed Data : BMC Neurosci. 2016 ;17(1):11. Epub 2016 Feb 8. PMID: 26856812

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress, Prenatal Chemical Exposures

Pharmacological Actions : Antioxidants

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View the Evidence: 1024 Abstracts with Carotenoids Research

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Astaxanthin influence on health outcomes of adults at risk of metabolic syndrome.May 12, 2022

Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers.Dec 29, 2021

Carotenoids supplementation and inflammation.May 16, 2021

Consumption of large amounts of tomato products may be associated with a reduced risk of gastric cancer.Mar 31, 2013

Dietary vitamin and carotenoid intake and risk of age-related cataract.Jan 08, 2019

Higher blood concentrations of lutein are generally associated with better cardiometabolic health.Jan 12, 2016

Higher concentrations of plasma carotenoids may reduce risk of urothelial cell carcinoma (UCC), in particular aggressive UCC.Sep 30, 2012

Higher dietary intakes of selenium, vitamin C, vitamin E, β-carotene and β-cryptoxanthin were associated with reduced pancreatic cancer risk.Jun 29, 2016

Higher intake of vitamin C, carotenoids, and α- tocopherol were associated with reduced risk of cardiovascular disease, total cancer, and all-cause mortality.Oct 31, 2018

Higher vitamin C intake and higher circulating concentrations of vitamin C, vitamin E and β-carotene are associated with a lower risk of CVD mortality.Jan 10, 2019

Supplementation of astaxanthin in the diet has positive effects on symptoms associated with obesity related diseases.May 07, 2021

Systematic review and meta-analysis on the effects of astaxanthin on human skin ageing.Aug 23, 2021

This meta-analysis suggests that blood retinol level is a double-edged sword for risk of hip fracture.Aug 31, 2014

Decreased intake of vegetables and fruits during pregnancy and the consequent decreased intake of nutrients such as folate and lutein/zeaxanthin, necessary for DNA methylation, synthesis, and retinal function, may increase risk for having a child with spJun 01, 2005

The effect of astaxanthin supplementation on performance and fat oxidation during a 40 km cycling time trial Jul 02, 2020

A blackcurrant product regulated the microbiota of volunteers and decreased the activity of βeta glucuronidase.Feb 28, 2014

A combination of nutrients improves age-related macular degeneration. Feb 01, 2008

A combined micronutrient dietary supplement should be considered in the overall management of AD.Sep 08, 2022

A diet rich in linoleic acid containing foods (e.g. white meats and fish) and beta-carotene was inversely related to HCC risk; iron intake was associated with increased risk. Nov 01, 2007

A dietary supplement containing astaxanthin and saw palmetto berry extract decrease dihydrotestosterone, increase testosterone and decrease estradiol levels in healthy males. Sep 01, 2009

A formula containing calcium, vitamin D3, lycopene , astaxantin and citrus bioflavonoids reducing climacteric symptoms in menopausal women. Jun 01, 2010

A greater intake of choline and lutein and zeaxanthin was associated with faster performance on a cognitive flexibility task in overweight people.Jan 14, 2021

Additional consumption of one egg per day increases serum lutein plus zeaxanthin concentration and lowers oxidized low-density lipoprotein.Aug 31, 2017

Alcohol consumption decreases the protection efficiency of the antioxidant network and increases the risk of sunburn in human skin.Dec 31, 2012

An antioxidant formula increases important fat-soluble nutrients and antioxidants and reduces airway inflammation in patients with Cystic Fibrosis. Jan 01, 2008

Annatto carotenoids attenuate oxidative stress and inflammatory response after high-calorie meal in healthy subjects.Jan 09, 2017

Antioxidant supplementation may have therapeutic value in the treatment of cystic fibrosis - Article 2. Jan 01, 2003

Antioxidant supplements prevent oxidation of cysteine/cystine redox in patients with age-related macular degeneration.Dec 01, 2005

Astaxanthin addition improves human neutrophils function.Dec 01, 2010

Astaxanthin and sesamin supplementation may be a candidate to promote recovery from mental fatigue.Feb 27, 2018

Astaxanthin appears to be an effective agent to increase endogenous antioxidant status.Oct 04, 2021

Astaxanthin derived from Haematococcus pluvialis improves the skin condition in both women and men.Mar 17, 2012

Astaxanthin has a positive effect on lipid profiles and oxidative stress in overweight subjects. Oct 01, 2011

Astaxanthin has antioxidant properties in soccer players.Nov 27, 2012

Astaxanthin improves glucose metabolism and reduces blood pressure in patients with type 2 diabetes mellitus.Dec 31, 2017

Astaxanthin improves human sperm capacitation by inducing lyn displacement and activation.Aug 24, 2015

Astaxanthin improves oxidative stress in overweight and obese adults. Apr 08, 2011

Astaxanthin increases blood flow in the eyes as measured by increased choroidal blood flow velocity.Nov 10, 2011

Astaxanthin prevents in vitro auto-oxidative injury in human lymphocytes.Oct 01, 2010

Astaxanthin protects smokers against oxidative stress. Sep 01, 2011

Astaxanthin reduces reflux symptoms in patients, especially in those with pronounced H. pylori infection.Jun 01, 2008

Astaxanthin seems protective against UV-induced skin deterioration and helps maintain healthy skin in healthy people.Jun 24, 2018

Astaxanthin significantly improves athletic performance as measured by cycling time. Oct 07, 2011

Astaxanthin supplementation enhances metabolic adaptation with aerobic training in the elderly.May 31, 2021

Astaxanthin supplementation improves sIgA response and attenuates muscle damage, thus preventing inflammation induced by rigorous physical training.Dec 31, 2014

Astaxanthin supplementation may have a beneficial effect on muscle damage and oxidative stress markers in atheletes. Jul 31, 2012

Astaxanthin supplementation reduces lipid peroxidation. Jan 01, 2007

Astaxanthin supplementation results in measurable improvement in the antioxidant status of human subjects. Jan 01, 2011

Astaxanthin treatment has been shown to increase both serum TAC levels and activation of the Nrf2 axis in PCOS patients' GCs.Mar 02, 2022

Astaxanthin, β-carotene, and resveratrol-rich foods support resistance training-induced adaptation.Jan 13, 2021

Astaxanthin-rich Haematococcus pluvialis extract improves cognitive function in the healthy aged individuals.Aug 31, 2012

Benefits and safety of astaxanthin in the treatment of mild-to-moderate dry eye disease.Dec 31, 2020

Beta-carotene has therapeutic value in the treatment of leukoplakias.Dec 01, 1999

Beta-carotene supplementation ameliorates deficiencies and reduces oxidative stress in Cystic Fibrosis patients. Jan 01, 2000

Beta-carotene, vitamin C and vitamin E deficiencies may play a role in the pathogenesis of thyroid cancer. Jun 01, 1997

Bioavailability Study: Administration After-Meal Significantly Improves Availability. Sep 01, 2009

Breast cancer risk may be affected by telomere length among premenopausal women or women with low dietary intake of antioxidants or antioxidant supplements. Apr 01, 2009

Carotenoids such as lycopene have a protective effect on bone health.Jun 01, 2009

Carotenoids, Vitamin C and E, reduce the risk of cataracts in women. Jan 01, 2008

Co-consuming cooked whole eggs is an effective way to enhance carotenoid absorption from other carotenoid-rich foods.May 26, 2015

Cognitive function improvement with astaxanthin and tocotrienol intake.Oct 31, 2020

Consumption of watermelon juice increases plasma concentrations of lycopene and beta-carotene in humans.Apr 01, 2003

Continuous astaxanthin consumption produces a strong antioxidant effect resulting in facial skin rejuvenation.Nov 30, 2017

crocetin could be considered as a promising anti-atherogenic candidate for future studies.Oct 31, 2019

Crocetin may have a suppressive effect on myopia progression in children.Aug 06, 2019

Daily consumption of a lutein-enriched egg drink for one year leads to a significant increase in visual acuity.Dec 31, 2015

Daily supplementation with carotenoids protects human skin against both UVB-induced erythema and UVA-induced pigmentation.Feb 17, 2020

Daily use of vitamin E, Vitamin C, and beta-carotene for three years produces a small deceleration in the progression of age-related cataract.Oct 01, 2001

Dietary antioxidants and fiber intake and depressive symptoms in Iranian adolescent girls.Nov 30, 2020

Dietary carotenoid intake and risk of developing preeclampsia.May 20, 2022

Dietary carotenoids lutein and zeaxanthin change brain activation in older adult participants.Apr 04, 2019

Dietary consumption of fruits high in antioxidant nutrients reduce the risk of incident cervical intraepithelial neoplasia.Sep 01, 2010

Carotenoids

View the Evidence:
1024 Abstracts with Carotenoids Research