Chinese Skullcap

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99 Diseases Researched for Chinese Skullcap
NameACCKFocus
Colorectal Cancer120Locked
Osteoarthritis110Locked
Osteoarthritis: Knee110Locked
Nonalcoholic fatty liver disease (NAFLD)15Locked
Asthma24Locked
Brain: Microglial Activation24Locked
Cancers: All44Locked
Influenza A34Locked
Pertussis24Locked
Anxiety Disorders23Locked
Parkinson's Disease23Locked
Abdominal Obesity (Midsection Fat)12Locked
Aging12Locked
Aging: Brain 12Locked
Alzheimer's Disease22Locked
Androgen-Induced Diseases12Locked
Anorexia: Cancer-Associated12Locked
Brain Inflammation 12Locked
Cachexia12Locked
Cervical Cancer12Locked
Cognitive Decline/Dysfunction12Locked
Corticosteroid-Induced Toxicity12Locked
Cortisol: High12Locked
Dementia12Locked
Dementia: Vascular12Locked
Diabetes Mellitus: Type 112Locked
Diabetic Retinopathy12Locked
Encephalitis12Locked
Endotoxemia12Locked
Fatty Liver12Locked
Fibrosis: Liver12Locked
Generalized Anxiety Disorder12Locked
Heat Stroke12Locked
Hyperalgesia12Locked
Hyperinsulinism12Locked
Hyperuricemia12Locked
Immune Dysregulation: TH1/TH2 imbalance12Locked
Inflammation12Locked
Intracranial Hypertension: Infection-Caused12Locked
Liver Fibrosis12Locked
Memory Loss12Locked
Multiple Myeloma22Locked
Multiple Sclerosis12Locked
Muscle Atrophy 12Locked
Obesity12Locked
Pain12Locked
Pancreatitis12Locked
Parkinsonism12Locked
Pneumocystis carinii12Locked
Prostatic Hyperplasia: Benign12Locked
Radiation Induced Illness12Locked
Restenosis12Locked
Shock: Toxic12Locked
Spinal Cord Injuries12Locked
Stress12Locked
Stroke: Attenuation/Recovery 12Locked
Sunburn12Locked
Trigeminal Neuralgia12Locked
Acute Myeloid Leukemia11Locked
Acute lymphoblastic leukemia (ALL)11Locked
Brain Cancer11Locked
Cancer Metastasis11Locked
Cancers: Estrogen Responsive11Locked
Candida Albicans11Locked
Candida Infection 11Locked
Cytomegalovirus Infections11Locked
Epstein-Barr Virus Infections11Locked
Escherichia coli Infections11Locked
Fluoride Toxicity 11Locked
Gastric Cancer11Locked
Glioblastoma Multiforme11Locked
HIV Infections11Locked
Hepatoma11Locked
Herpes Simplex Virus Type 111Locked
Human Influenza11Locked
Influenza in Swine11Locked
Iron Overload11Locked
Iron Poisoning11Locked
Leukemia: Acute myelogenous leukemia (AML) 11Locked
Liver Cancer11Locked
Lyme Disease11Locked
Lymphoma11Locked
Osteosarcoma11Locked
Pancreatic Cancer11Locked
Periodontal Diseases11Locked
Preterm birth: Uterus Contractions11Locked
Promyelocytic leukemia 11Locked
Prostate Cancer11Locked
Staphylococcus epidermidis11Locked
Steroid-Induced Toxicity11Locked
Testicular Cancer11Locked
Testicular Neoplasms11Locked
Tongue Cancer11Locked
Toxoplasma gondii Infection11Locked
Toxoplasmosis11Locked
Tumors11Locked
Vesicular Stomatitis Virus11Locked
Virally-Induced Cytokine Storm11Locked
X-Linked Adrenoleukodystrophy11Locked
45 Pharmacological Actions Researched for Chinese Skullcap
NameACCKFocus
Apoptotic1113Locked
Antiviral Agents911Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor59Locked
Antioxidants68Locked
Neuroprotective Agents68Locked
Anti-Inflammatory Agents47Locked
Antiproliferative 57Locked
NF-kappaB Inhibitor47Locked
Interleukin-1 beta downregulation36Locked
Analgesics24Locked
Interleukin-4 downregulation24Locked
Interleukin-5 downregulation24Locked
Interleukin-6 Downregulation24Locked
Anti-Anxiety Agents23Locked
Anti-Bacterial Agents23Locked
Cyclooxygenase 2 Inhibitors23Locked
Anti-metastatic22Locked
Antiparasitic Agents22Locked
Cell cycle arrest22Locked
Chemosensitizer22Locked
Immunomodulatory12Locked
Intercellular adhesion molecule 3 down-regulation12Locked
Interleukin-10 upregulation12Locked
Malondialdehyde Down-regulation12Locked
Nitric Oxide Inhibitor12Locked
Radioprotective12Locked
Telomerase Inhibitor22Locked
Vascular Endothelial Growth Factor A Inhibitor12Locked
Angiogenesis Inhibitors11Locked
Anti-Angiogenic11Locked
Antibacterial Effects11Locked
Anticarcinogenic Agents11Locked
Antifungal Agents11Locked
Antineoplastic Agents11Locked
Antiprotozoal Agents11Locked
Cyclin-Dependent Kinase Inhibitor 11Locked
Cytotoxic11Locked
Enzyme Inhibitors11Locked
Multidrug Resistance Gene Modulators11Locked
NF-E2-Related Factor-2 (Nrf2) Modulator11Locked
Neurominidase Inhibitor11Locked
Reverse Transcriptase Inhibitors11Locked
Tocolytic Agents11Locked
Tumor Necrosis Factor (TNF) Alpha Enhancer11Locked
VEGFR3 inhibition 11Locked

View the Evidence:
96 Abstracts with Chinese Skullcap Research

[+]

Specific combinations of traditional medicines appeared to produce higher contributions to tumor response rate than the TMs individually.Aug 05, 2015

Pubmed Data : Integr Cancer Ther. 2015 Aug 6. Epub 2015 Aug 6. PMID: 26254190
Article Published Date : Aug 05, 2015
Study Type : Meta Analysis
Additional Links
Substances : Astragalus, Chinese Skullcap , Hedyotis corymbosa
Diseases : Colorectal Cancer
Additional Keywords : Drug: Oxaliplatin, Natural Substance/Drug Synergy
[+]

A combination of baicalin (a compound found within Chinese skullcap) and catechin (a polyphenol plant antioxidant) are as effective as naproxen in treating osteoarthritis of the knee. Dec 01, 1985

Pubmed Data : J Pediatr Gastroenterol Nutr. 1985 Dec;4(6):923-30. PMID: 19555810
Article Published Date : Dec 01, 1985
Study Type : Human Study
Additional Links
Substances : Catechin , Chinese Skullcap
Diseases : Osteoarthritis, Osteoarthritis: Knee
Additional Keywords : Natural Substances Versus Drugs
[+]

Chinese skullcap regulates free fatty acid metabolism to ameliorate nonalcoholic fatty liver disease.Jun 01, 2018

Pubmed Data : J Nat Med. 2018 Jun ;72(3):655-666. Epub 2018 Mar 14. PMID: 29542003
Article Published Date : Jun 01, 2018
Study Type : Human In Vitro
Additional Links
Substances : Chinese Skullcap
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Additional Keywords : Plant Extracts
[+]

Baicalin improved hepatic injury of NASH by regulating NRF2/HO-1/NRLP3 pathway.Nov 04, 2022

Pubmed Data : Eur J Pharmacol. 2022 Nov 5 ;934:175270. Epub 2022 Sep 20. PMID: 36184988
Article Published Date : Nov 04, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids, Skullcap: Chinese
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Hepatoprotective, Nrf2 activation
[+]

A compound extracted from Chinese skullcap known as baicalein has neuroprotective effects in experimental parkinsonianism in vivo and in vitro. Jun 01, 2009

Pubmed Data : Pharmacol Biochem Behav. 2009 Jun;92(4):642-8. Epub 2009 Mar 25. PMID: 19327378
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Parkinson's Disease, Parkinsonism
[+]

A compound in Chinese skullcap known as baicalein reduces the inflammatory process in a rodent model of diabetic retinopathyMay 01, 2009

Pubmed Data : Invest Ophthalmol Vis Sci. 2009 May;50(5):2319-27. Epub 2008 Nov 14. PMID: 19011009
Article Published Date : May 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Brain: Microglial Activation, Diabetic Retinopathy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor A Inhibitor
[+]

A lettuce and skullcap mixture can be used as an herbal agent for sleep disorders.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2018 ;41(8):1269-1276. PMID: 30068876
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Lettuce, Skullcap: Chinese
Diseases : Sleep Disorders
Additional Keywords : Plant Extracts
[+]

Baicalein attenuates radiation-induced inflammatory process in mouse kidney.May 01, 2011

Pubmed Data : Free Radic Res. 2011 May;45(5):507-17. Epub 2011 Feb 1. PMID: 21284490
Article Published Date : May 01, 2011
Study Type : Animal Study
Additional Links
Substances : Baicalein, Chinese Skullcap
Diseases : Radiation Induced Illness
Pharmacological Actions : Radioprotective
[+]

Baicalein mediates protection against Staphylococcus aureus-induced pneumonia.May 12, 2020

Pubmed Data : Biochem Pharmacol. 2020 May 13 ;178:114024. Epub 2020 May 13. PMID: 32413427
Article Published Date : May 12, 2020
Study Type : Animal Study
Additional Links
Substances : Skullcap: Chinese
Diseases : Staphylococcus aureus infection, Streptococcus pneumoniae infection
Pharmacological Actions : Anti-Bacterial Agents
[+]

Baicalein, a compound found within Chinese skullcap, has an inhibitory effect on prostatic hyperplasia in experimental animals.Mar 01, 2004

Pubmed Data : Biol Pharm Bull. 2004 Mar;27(3):333-7. PMID: 14993798
Article Published Date : Mar 01, 2004
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Androgen-Induced Diseases, Prostatic Hyperplasia: Benign
Pharmacological Actions : Antiproliferative
[+]

Baicalein, a compound found within Chinese skullcap, has antifibrotic effects in a liver fibrosis model in rats. Apr 10, 2010

Pubmed Data : Eur J Pharmacol. 2010 Apr 10;631(1-3):53-60. Epub 2010 Jan 13. PMID: 20079350
Article Published Date : Apr 10, 2010
Study Type : Animal Study
Additional Links
Substances : Skullcap: Chinese
Diseases : Liver Fibrosis
Pharmacological Actions : Hepatoprotective
[+]

Baicalein, a compound found within Chinese skullcap, may prevent restenosis after artery injury. Dec 01, 2008

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2008 Dec;378(6):579-88. Epub 2008 Jul 29. PMID: 18663431
Article Published Date : Dec 01, 2008
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Restenosis
[+]

Baicalein, a compound found within Chinese skullcap, prevents noise-induced hearing loss.Jan 29, 2010

Pubmed Data : Neurosci Lett. 2010 Jan 29;469(3):298-302. Epub 2009 Dec 11. PMID: 20004700
Article Published Date : Jan 29, 2010
Study Type : Animal Study
Additional Links
Substances : Skullcap: Chinese
Diseases : Hearing Loss: Noise-Induced
[+]

Baicalein, a compound found within Chinese skullcap, protects gainst endotoxic shock in rats in vivo and in vitro. Mar 15, 2007

Pubmed Data : Biochem Pharmacol. 2007 Mar 15;73(6):793-804. Epub 2006 Dec 2. PMID: 17182007
Article Published Date : Mar 15, 2007
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Endotoxemia, Shock: Toxic
Pharmacological Actions : NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Baicalein, wogonin, and Scutellaria baicalensis ethanol extract alleviate ovalbumin-induced allergic airway inflammation May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anat Cell Biol. 2017 Jun ;50(2):124-134. Epub 2017 Jun 27. PMID: 28713616
Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Substances : Baicalein, Chinese Skullcap , Wogonin
Diseases : Asthma
Pharmacological Actions : Immunomodulatory, Interleukin-1 beta downregulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

Baicalin inhibits age-associated NF-kappaB activiation. Sep 01, 2006

Pubmed Data : Mech Ageing Dev. 2006 Sep;127(9):719-25. Epub 2006 Jun 12. PMID: 16766019
Article Published Date : Sep 01, 2006
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Aging
Pharmacological Actions : NF-kappaB Inhibitor
[+]

Baicalin suppresses body weight gain, visceral fat mass, serum cholesterol, free fatty acid and insulin concentrations caused by a high-fat diet. Nov 01, 2009

Pubmed Data : Acta Pharmacol Sin. 2009 Nov;30(11):1505-12. PMID: 19890358
Article Published Date : Nov 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Abdominal Obesity (Midsection Fat), Fatty Liver, Hyperinsulinism, Obesity
[+]

Baicalin treatment effectively ameliorates anorexia by inhibiting cytokine expression and prevents skeletal muscle atrophy in mice.Sep 07, 2014

Pubmed Data : Tumour Biol. 2014 Sep 8. Epub 2014 Sep 8. PMID: 25195133
Article Published Date : Sep 07, 2014
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Anorexia: Cancer-Associated, Cachexia, Muscle Atrophy
Pharmacological Actions : Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Baicalin, a compound found within Chinese skullcap, has a therapeutic effect in rats with severe acute pancreatitis. Nov 01, 2009

Pubmed Data : Am J Clin Nutr. 2009 Nov;90(5):1402-10. Epub 2009 Sep 30. PMID: 19657312
Article Published Date : Nov 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Pancreatitis
[+]

Baicalin, a compound found within Chinese skullcap, is as effective as ibuprofen as an analgesic in an experiemental model of hyperalgesia. Dec 01, 2003

Pubmed Data : Anesth Analg. 2003 Dec;97(6):1724-9. PMID: 14633550
Article Published Date : Dec 01, 2003
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Hyperalgesia, Pain
Pharmacological Actions : Analgesics
Additional Keywords : Baicalin, Ibuprofen Alternatives, Natural Substances Versus Drugs
[+]

Baicalin, a compound found within Chinese skullcap, may alleviate inflammation in lung tissues of rats infected with Pneumocystis carinii. Apr 01, 2009

Pubmed Data : Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2009 Apr;27(2):144-7. PMID: 19856505
Article Published Date : Apr 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Pneumocystis carinii
Pharmacological Actions : Intercellular adhesion molecule 3 down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Baicalin, a compound found within Chinese skullcap, reduce the adverse effects of ultraviolet B-mediated damage in mouse skin. Oct 01, 2009

Pubmed Data : Photodermatol Photoimmunol Photomed. 2009 Oct;25(5):250-8. PMID: 19747244
Article Published Date : Oct 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Sunburn
[+]

Chinense skullcap counteracts influenza virus infection in mice. Nov 01, 2007

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2007 Nov;32(22):2413-5. PMID: 18257272
Article Published Date : Nov 01, 2007
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Influenza A
Pharmacological Actions : Antiviral Agents
[+]

Chinese skullcap (Scutellaria baicalensis) significantly improves functional recovery from spinal cord injury in rats by inhibiting inflammation and oxidative stress after injury.Aug 01, 2009

Pubmed Data : J Neurochem. 2009 Aug;110(4):1276-87. Epub 2009 Jun 10. PMID: 19519665
Article Published Date : Aug 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Brain: Microglial Activation, Spinal Cord Injuries
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Apoptotic, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

Chinese skullcap contains a compound known as baicalin which has protective effects on infective brain edema in rats caused by the injfection of pertussis bacilli - Article 2. Aug 01, 1998

Pubmed Data : Zhonghua Yi Xue Za Zhi. 1998 Aug;78(8):630-2. PMID: 11038818
Article Published Date : Aug 01, 1998
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Pertussis
Pharmacological Actions : Anti-Bacterial Agents
[+]

Chinese skullcap contains a compound known as baicalin which has protective effects on infective brain edema in rats caused by the injfection of pertussis bacilli.Mar 01, 1985

Pubmed Data : Arch Pathol Lab Med. 1985 Mar;109(3):283-6. PMID: 12212190
Article Published Date : Mar 01, 1985
Study Type : Animal Study
Additional Links
Substances : Skullcap: Chinese
Diseases : Pertussis
Pharmacological Actions : Neuroprotective Agents
[+]

Chinese skullcap contains a compound known as baicalin which reduces intracranial hypertension associated with pertussis infection in the brain of rabbits.Apr 01, 1999

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 1999 Apr;19(4):224-6. PMID: 11783272
Article Published Date : Apr 01, 1999
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Intracranial Hypertension: Infection-Caused, Pertussis
[+]

Chinese skullcap contains a compound, Baicalin, which may favorably alter the TH1/TH2 balance in asthma. Sep 01, 2009

Pubmed Data : Zhong Yao Cai. 2009 Sep;32(9):1407-10. PMID: 20034219
Article Published Date : Sep 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Asthma, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Interleukin-10 upregulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

Chinese skullcap contains compounds with significant anti-anxiety activity. Mar 19, 2003

Pubmed Data : Eur J Pharmacol. 2003 Mar 19;464(2-3):141-6. PMID: 12620506
Article Published Date : Mar 19, 2003
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Anxiety Disorders, Generalized Anxiety Disorder
Pharmacological Actions : Anti-Anxiety Agents
Additional Keywords : Benzodiazepine Receptor Agonist
[+]

Chinese skullcap is an effective therapeutic agent in an experimental model of Multiple Sclerosis. Jul 01, 2007

Pubmed Data : Braz J Med Biol Res. 2007 Jul;40(7):1003-10 PMID: 17653455
Article Published Date : Jul 01, 2007
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Encephalitis, Multiple Sclerosis
Pharmacological Actions : Antiviral Agents
Additional Keywords : Undefined
[+]

Efficacy confirmation of Scutellaria baicalensis Georgi in the treatment of periodontitis.Jan 09, 2023

Pubmed Data : J Ethnopharmacol. 2023 Jan 10 ;300:115699. Epub 2022 Sep 14. PMID: 36113679
Article Published Date : Jan 09, 2023
Study Type : Animal Study
Additional Links
Substances : Skullcap: Chinese
Diseases : Lipopolysaccharide-Induced Toxicity, Periodontitis
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

Radix scutellariae and baicalin inhibited CYP7A1 expression, improved bile acid, and glycolipid metabolism in T2DM.Jul 14, 2022

Pubmed Data : J Ethnopharmacol. 2022 Jul 15 ;293:115238. Epub 2022 Mar 26. PMID: 35351576
Article Published Date : Jul 14, 2022
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Skullcap: Chinese
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
[+]

Schisandra and Scutellaria baicalensis (Chinese skullcap) counter stress behavior in mice. Dec 01, 2007

Pubmed Data : Phytother Res. 2007 Dec;21(12):1187-92. PMID: 17639560
Article Published Date : Dec 01, 2007
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap , Schisandra
Diseases : Cortisol: High, Stress
[+]

Scutellaria baicalensis (skullcap) enhances the anti-diabetic activity of metformin in diabetic rats. Jan 01, 2008

Pubmed Data : Am J Chin Med. 2008;36(3):517-40. PMID: 18543386
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Diabetes Mellitus: Type 1
Additional Keywords : Drug: Metformin, Drug-Plant-Vitamin Synergies, Metformin Alternatives
[+]

Scutellaria baicalensis (skullcap) may contribute to reversal of fibrosis through induction of programmed cell death in hepatic stellate cells. Aug 01, 2009

Pubmed Data : Antiviral Res. 2009 Aug;83(2):165-70. Epub 2009 May 3. PMID: 16206047
Article Published Date : Aug 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Fibrosis: Liver, Liver Fibrosis
[+]

Scutellaria baicalensis Georgi regulates REV-ERBα/BMAL1 to protect against skin aging in mice.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:991917. Epub 2022 Sep 30. PMID: 36249807
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Skullcap: Chinese
Diseases : Aging Skin
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
[+]

Scutellaria biacalensis reverses aging-related cognitive impairment and neuronal changes in aged rats. Feb 01, 2009

Pubmed Data : Brain Inj. 2009 Feb;23(2):146-53. PMID: 19191093
Article Published Date : Feb 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Aging: Brain , Cognitive Decline/Dysfunction, Dementia
Pharmacological Actions : Neuroprotective Agents
[+]

Siberian ginseng (Acanthopanax senticosus), Angelica sinensis and Scutellaria baicalensis (Chinese skullcap) protect against urate crystal induced inflammation in a mouse experimental model. Aug 01, 2008

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2008 Aug;17(8):2136-45. PMID: 17612394
Article Published Date : Aug 01, 2008
Study Type : Animal Study
Additional Links
Substances : Angelica, Chinese Skullcap , Ginseng (Siberian)
Diseases : Hyperuricemia, Inflammation
[+]

Skullcap baicalensis flavonoid reduces memory dysfunction and neuronal injury caused by global ischemia in rats. Sep 01, 2005

Pubmed Data : Pharmacol Biochem Behav. 2005 Sep;82(1):67-73. Epub 2005 Aug 29. PMID: 16129477
Article Published Date : Sep 01, 2005
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Dementia: Vascular, Memory Loss, Stroke: Attenuation/Recovery
[+]

The flavonoid baicalin found in Chinese skullcap protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke.Mar 01, 2007

Pubmed Data : Neuropharmacology. 2007 Mar;52(3):1024-33. Epub 2007 Jan 3. PMID: 17204294
Article Published Date : Mar 01, 2007
Study Type : Animal Study
Additional Links
Substances : Catechols, Chinese Skullcap , Flavonoids
Diseases : Brain Inflammation , Heat Stroke
[+]

The leaves of Scutellaria baicalensis Georgi attenuate brain aging.Oct 12, 2022

Pubmed Data : Exp Gerontol. 2022 Oct 13:111978. Epub 2022 Oct 13. PMID: 36244586
Article Published Date : Oct 12, 2022
Study Type : Animal Study
Additional Links
Substances : Skullcap: Chinese
Diseases : Aging: Brain
Pharmacological Actions : Neuroprotective Agents
[+]

The traditional Japanese herbal formula Saiko-Keishi-To controls pain in trigeminal neuralgia in rats. May 01, 2001

Pubmed Data : Masui. 2001 May;50(5):486-90. PMID: 11424461
Article Published Date : May 01, 2001
Study Type : Animal Study
Additional Links
Substances : Bupleurum, Chinese Skullcap , Cinnamon, Ginger, Japanese Herbal Formula: Sho-saiko-to, Jujube, Licorice, Peony, Pinellia
Diseases : Trigeminal Neuralgia
Pharmacological Actions : Analgesics
[+]

Vitamin C and Baicalin inhibits tumor growth by enhancing the antioxidant capacity in vivo.Aug 31, 2015

Pubmed Data : J BUON. 2015 Sep-Oct;20(5):1368-72. PMID: 26537087
Article Published Date : Aug 31, 2015
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap , Vitamin C
Diseases : Cervical Cancer
Pharmacological Actions : Antioxidants, Antiproliferative , Malondialdehyde Down-regulation
Additional Keywords : Natural Substance Synergy
[+]

Wogonin, a compound found within Chinese Skullcap, prevents immunosuppressive action but not anti-inflammatory effect induced by glucocorticoid.Jul 01, 2008

Pubmed Data : Dig Dis Sci. 2008 Jul;53(7):1774-84. Epub 2008 Mar 27. PMID: 17404053
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap , Wogonin
Diseases : Corticosteroid-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic
[+]

A comprehensive review of herbal supplements used for persistent symptoms attributed to lyme disease.Feb 28, 2023

Pubmed Data : Integr Med (Encinitas). 2023 Mar ;22(1):30-38. PMID: 37101730
Article Published Date : Feb 28, 2023
Study Type : Review
Additional Links
Substances : Andrographis, Astragalus, Chinese Skullcap , Cordyceps sinensis, Garlic, Lemon Balm, Oregano, Peppermint, Reishi Mushroom, Thyme, Wormwood
Diseases : Lyme Disease
Pharmacological Actions : Antiparasitic Agents
[+]

Advances in anti-cancer activities of flavonoids in Scutellariae radix: perspectives on mechanism.Sep 19, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Sep 20 ;23(19). Epub 2022 Sep 20. PMID: 36232344
Article Published Date : Sep 19, 2022
Study Type : Review
Additional Links
Substances : Flavonoids, Skullcap: Chinese, Wogonin
Diseases : Cancers: All
Pharmacological Actions : Chemotherapeutic
[+]

Alzheimer's disease drug discovery from herbs: neuroprotectivity from beta-amyloid (1-42) insult.Mar 31, 2007

Pubmed Data : J Altern Complement Med. 2007 Apr ;13(3):333-40. PMID: 17480132
Article Published Date : Mar 31, 2007
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap , Ginger, Ginkgo biloba
Pharmacological Actions : Apoptotic, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Anti-inflammatory action of herbal medicine comprised of Scutellaria baicalensis and Chrysanthemum morifolium.May 23, 2020

Pubmed Data : Biosci Biotechnol Biochem. 2020 May 24:1-11. Epub 2020 May 24. PMID: 32448093
Article Published Date : May 23, 2020
Study Type : In Vitro Study
Additional Links
Substances : Chrysanthemum Morifolium, Skullcap: Chinese
Diseases : Chronic Obstructive Pulmonary Disease, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-12 downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Postaglandin PGE2 downregulation
Additional Keywords : Plant Extracts
[+]

Anti-tumor and anti-metastatic actions of wogonin isolated from Scutellaria baicalensis roots through anti-lymphangiogenesis.Feb 14, 2013

Pubmed Data : Phytomedicine. 2013 Feb 15 ;20(3-4):328-36. Epub 2012 Dec 6. PMID: 23219337
Article Published Date : Feb 14, 2013
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap , Wogonin
Diseases : Osteosarcoma
Pharmacological Actions : Anti-metastatic, Cyclooxygenase 2 Inhibitors, VEGFR3 inhibition
Additional Keywords : Phytotherapy
[+]

Antifibrotic activities of Scutellariae Radix extracts and flavonoids.May 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytomedicine. 2022 Jun ;100:154049. Epub 2022 Mar 19. PMID: 35397287
Article Published Date : May 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Skullcap: Chinese
Diseases : Fibrosis
Pharmacological Actions : Anti-Fibrotic
Additional Keywords : Plant Extracts
[+]

Baicalein reverses 5-FU resistance in cancer cells under hypoxia.Oct 16, 2014

Pubmed Data : Oncol Rep. 2014 Oct 17. Epub 2014 Oct 17. PMID: 25333894
Article Published Date : Oct 16, 2014
Study Type : In Vitro Study
Additional Links
Substances : Baicalein, Chinese Skullcap
Diseases : Gastric Cancer
Pharmacological Actions : Chemosensitizer, Enzyme Inhibitors
[+]

Baicalein, a compound found within Chinese skullcap, induces programmed cell death in Candida Albicans. Aug 01, 2009

Pubmed Data : J Microbiol Biotechnol.2009 Aug;19(8):803-9. PMID: 19734718
Article Published Date : Aug 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Candida Infection
Pharmacological Actions : Apoptotic
[+]

Baicalein, a compound found within Chinese skullcap, is protective against oxidative stress in osteoblasts exposed to flouride. Apr 01, 2007

Pubmed Data : Biol Trace Elem Res. 2007 Apr;116(1):81-9. PMID: 17634630
Article Published Date : Apr 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Fluoride Toxicity
[+]

Baicalein, a compound found within Chinese skullcap, may have a therapeutic role in the treatment of X-linked adrenoleukodystrophy. Jan 17, 2005

Pubmed Data : FEBS Lett. 2005 Jan 17;579(2):409-14. PMID: 15642351
Article Published Date : Jan 17, 2005
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : X-Linked Adrenoleukodystrophy
[+]

Baicalein, a compound found within Skullcap, suppresses proliferation and induces programmed cell death in human myeloma cells. Apr 15, 2005

Pubmed Data : Blood. 2005 Apr 15;105(8):3312-8. Epub 2004 Dec 30. PMID: 15626742
Article Published Date : Apr 15, 2005
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Multiple Myeloma
Pharmacological Actions : Apoptotic
[+]

Baicalein, a compound from Chinese skullcap, induces programmed cell death in human tongue cancer cells. Nov 01, 2007

Pubmed Data : In Vivo. 2007 Nov-Dec;21(6):1053-8. PMID: 18210755
Article Published Date : Nov 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Tongue Cancer
[+]

Baicalin, a flavonoid from within Chinese skullcap, inhibits HIV-1 infection and replication. Jan 01, 1993

Pubmed Data : Cell Mol Biol Res. 1993;39(2):119-24. PMID: 7693133
Article Published Date : Jan 01, 1993
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : HIV Infections
Pharmacological Actions : Antiviral Agents, Reverse Transcriptase Inhibitors
[+]

Both Astragalus membranaceus and Scutellaria baicalensis had remarkable in vitro activities against T. gondii.May 31, 2012

Pubmed Data : Parasitol Res. 2012 Jun ;110(6):2221-7. Epub 2011 Dec 17. PMID: 22179265
Article Published Date : May 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Astragalus, Chinese Skullcap
Diseases : Toxoplasma gondii Infection, Toxoplasmosis
Pharmacological Actions : Antiparasitic Agents, Antiprotozoal Agents
Additional Keywords : Plant Extracts
[+]

Cancer stem cells and the potential targets of Chinese medicines and their active compounds.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 ;17(6). Epub 2016 Jun 7. PMID: 27338343
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Berberine, Carrot, Chinese Skullcap , Coptis chinensis, Curcumin, EGCG (Epigallocatechin gallate), Quercetin, Resveratrol, Sophora Flavescens
Diseases : Cancers: All
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Multidrug Resistance Gene Modulators
Additional Keywords : Chinese Traditional Medicine
[+]

Chinese Scullcap (baicalein) has anticancer activity in prostate cancer.Oct 01, 2002

Pubmed Data : J Altern Complement Med. 2002 Oct;8(5):567-72. PMID: 12470437
Article Published Date : Oct 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Prostate Cancer
[+]

Chinese Scullcap (wogonin) has neuroprotective effect by preventing the overactivation of microglial cells.Sep 01, 2004

Pubmed Data : Arch Pharm Res. 2004 Sep;27(9):930-6. PMID: 15473663
Article Published Date : Sep 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Chinese skullcap (baicalein) protects dopaminergic cells and may have application in the treatment of Parkinson's diseaseMar 01, 2005

Pubmed Data : J Neural Transm. 2005 Mar;112(3):331-47. Epub 2004 Oct 22. PMID: 15503194
Article Published Date : Mar 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Lipopolysaccharide-Induced Damage
[+]

Chinese skullcap (S. baicalensis) has anticancer activity on human malignant brain tumor cells. Aug 16, 2006

Pubmed Data : BMC Complement Altern Med. 2006 Aug 16;6:27. PMID: 16914050
Article Published Date : Aug 16, 2006
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Brain Cancer, Glioblastoma Multiforme
[+]

Chinese skullcap contains compounds which inhibit human hepatoma and pancreatic cancer cell lines in vitro. Oct 28, 1994

Pubmed Data : Cancer Lett. 1994 Oct 28;86(1):91-5. PMID: 7954360
Article Published Date : Oct 28, 1994
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Hepatoma, Pancreatic Cancer
[+]

Chinese skullcap contains several compounds with anti-angiogenic activity which may be of value in the treatment of cancer. Sep 10, 2003

Pubmed Data : Int J Cancer. 2003 Sep 10;106(4):559-65. PMID: 12845652
Article Published Date : Sep 10, 2003
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Cancer Metastasis, Cancers: All
Pharmacological Actions : Anti-Angiogenic, Antiproliferative
[+]

Chinese skullcap has significant anti-viral activity against Influenza.May 01, 1990

Pubmed Data : Chem Pharm Bull (Tokyo). 1990 May;38(5):1329-32. PMID: 2393958
Article Published Date : May 01, 1990
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Human Influenza, Influenza A, Influenza in Swine
Pharmacological Actions : Antiviral Agents, Neurominidase Inhibitor
[+]

Chinese skullcap induces cell death in Acute Lymphocytic Leukemia, Lymphoma and Myeloma cell lines.Apr 01, 2007

Pubmed Data : Leuk Res. 2007 Apr;31(4):523-30. Epub 2006 Sep 26. PMID: 17007926
Article Published Date : Apr 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Acute lymphoblastic leukemia (ALL), Lymphoma, Multiple Myeloma
Pharmacological Actions : Apoptotic
[+]

Chinese skullcap inhibits Epstein-Barr activation and tumor promotion.Feb 01, 1992

Pubmed Data : Chem Pharm Bull (Tokyo). 1992 Feb;40(2):531-3. PMID: 1318792
Article Published Date : Feb 01, 1992
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap , Flavonoids
Diseases : Epstein-Barr Virus Infections, Tumors
Pharmacological Actions : Anticarcinogenic Agents, Antiviral Agents, Cell cycle arrest
[+]

Chinese skullcap inhibits the growth of an estrogen-responsive mouse tumor cell line.May 01, 2011

Pubmed Data : Oncol Rep. 2011 May;25(5):1431-8. Epub 2011 Mar 1. PMID: 21369700
Article Published Date : May 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Cancers: Estrogen Responsive, Testicular Cancer, Testicular Neoplasms
Pharmacological Actions : Apoptotic, Cell cycle arrest, Cyclin-Dependent Kinase Inhibitor , NF-kappaB Inhibitor, Telomerase Inhibitor
[+]

Chinese skullcap may suppress premature labor. Mar 04, 2009

Pubmed Data : J Biomed Sci. 2009 Mar 4;16:27. PMID: 19272127
Article Published Date : Mar 04, 2009
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Preterm birth: Uterus Contractions
Pharmacological Actions : Tocolytic Agents
[+]

Comprehensive insights into pathophysiology of Alzheimer's disease: herbal approaches for mitigating neurodegeneration.Apr 14, 2024

Pubmed Data : Curr Alzheimer Res. 2024 Apr 15. Epub 2024 Apr 15. PMID: 38623983
Article Published Date : Apr 14, 2024
Study Type : Review
Additional Links
Substances : Omega 3 Fatty Acids, Pomegranate, Resveratrol, Skullcap: Chinese, Turmeric
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Evaluation of natural and botanical medicines for activity against growing and non-growing forms of B. burgdorferi.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Med (Lausanne). 2020 ;7:6. Epub 2020 Feb 21. PMID: 32154254
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Black Walnut, Cat's Claw, Cistus, Skullcap: Chinese, Stevia, Wormwood
Diseases : Lyme Disease
Pharmacological Actions : Anti-Bacterial Agents
[+]

Genistein and especially Baicalein (Chinese Skullcap) inhibit human cytomegalovirus. Dec 01, 2005

Pubmed Data : Antiviral Res. 2005 Dec;68(3):124-34. Epub 2005 Sep 15. PMID: 16188329
Article Published Date : Dec 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap , Genistein
Diseases : Cytomegalovirus Infections
Pharmacological Actions : Antiviral Agents
[+]

Mechanism of Radix Scutellariae in the treatment of influenza A based on network pharmacology and molecular docking.Feb 28, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Transl Med. 2022 Mar ;10(6):351. PMID: 35433930
Article Published Date : Feb 28, 2022
Study Type : In Vitro Study
Additional Links
Substances : Skullcap: Chinese
Diseases : Influenza
Pharmacological Actions : Antiviral Agents
[+]

Mechanisms involved in therapeutic effects of Scutellaria baicalensis in oral squamous cell carcinoma.Dec 31, 2023

Pubmed Data : Biomed Res Int. 2024 ;2024:1236910. Epub 2024 Jan 30. PMID: 38322303
Article Published Date : Dec 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Skullcap: Chinese
Diseases : Oral Cancer, Squamous cell carcinoma
Pharmacological Actions : Chemotherapeutic
[+]

Multi-target neuroprotective effects of herbal medicines for Alzheimer's disease.Feb 13, 2022

Pubmed Data : J Ethnopharmacol. 2022 Feb 14 ;290:115107. Epub 2022 Feb 14. PMID: 35176467
Article Published Date : Feb 13, 2022
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap , Fenugreek, Ginkgo biloba, Lavender, Rosemary, St. Johns Wort, Turmeric
Diseases : Alzheimer's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Potential antidepressant effects of Scutellaria baicalensis, Hericium erinaceus and Rhodiola rosea.Mar 11, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Mar 12 ;9(3). Epub 2020 Mar 12. PMID: 32178272
Article Published Date : Mar 11, 2020
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus), rhodiola, Skullcap: Chinese
Diseases : Anxiety, Depression
Pharmacological Actions : Anti-Anxiety Agents, Anti-Inflammatory Agents, Antidepressive Agents, Antioxidants, Neuroprotective Agents
[+]

Promising role of the Scutellaria baicalensis root hydroxyflavone-baicalein in the prevention and treatment of human diseases.Feb 28, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2023 Mar 1 ;24(5). Epub 2023 Mar 1. PMID: 36902160
Article Published Date : Feb 28, 2023
Study Type : Review
Additional Links
Substances : Baicalein, Chinese Skullcap , Flavonoids
Diseases : Cancers: All, Candida Albicans, Escherichia coli Infections, Herpes Simplex Virus Type 1, Staphylococcus epidermidis
Pharmacological Actions : Anti-Bacterial Agents, Antifungal Agents, Antioxidants, Antiviral Agents
Additional Keywords : Plant Extracts
[+]

Research progress of active ingredients of Scutellaria baicalensis in the treatment of type 2 diabetes and its complications.Feb 10, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 Feb 11 ;148:112690. Epub 2022 Feb 11. PMID: 35158145
Article Published Date : Feb 10, 2022
Study Type : Review
Additional Links
Substances : Flavonoids, Skullcap: Chinese
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Insulin Sensitizers, Renoprotective
[+]

S. baicalensis free flavones showed potent anti-influenza, anti-cancer and anti-oxidative activities.Dec 23, 2015

Pubmed Data : J Ethnopharmacol. 2015 Dec 24 ;176:475-84. Epub 2015 Nov 11. PMID: 26578185
Article Published Date : Dec 23, 2015
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Influenza A
Pharmacological Actions : Antioxidants, Antiviral Agents, Cytotoxic, NF-E2-Related Factor-2 (Nrf2) Modulator
[+]

Scutellaria baicalensis (Chinese skullcap) stimulates resistance to viral infection in human leukocytes through the beneficial modulation of cytokines. Sep 01, 2008

Pubmed Data : J Interferon Cytokine Res. 2008 Sep;28(9):571-81. PMID: 18771341
Article Published Date : Sep 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Vesicular Stomatitis Virus, Virally-Induced Cytokine Storm
Pharmacological Actions : Antiviral Agents, Tumor Necrosis Factor (TNF) Alpha Enhancer
Additional Keywords : Cytokine Modulation
[+]

Scutellaria baicalensis georgi is a promising candidate for the treatment of autoimmune diseases.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:946030. Epub 2022 Sep 16. PMID: 36188625
Article Published Date : Dec 31, 2021
Study Type : Review
Additional Links
Substances : Skullcap: Chinese
Diseases : Autoimmune Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
[+]

Scutellaria baicalensis in the treatment of hepatocellular carcinoma.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2023 ;2023:4572660. Epub 2023 Feb 23. PMID: 36874613
Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Skullcap: Chinese
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative
[+]

Skullcap has anxiolytic effects similar to benzodiazepine without the sedative and myorelaxant side-effects. Nov 01, 2002

Pubmed Data : Biochem Pharmacol. 2002 Nov 1;64(9):1415-24. PMID: 12392823
Article Published Date : Nov 01, 2002
Study Type : Review
Additional Links
Substances : Chinese Skullcap
Diseases : Anxiety Disorders
Pharmacological Actions : Anti-Anxiety Agents
Additional Keywords : Benzodiazepine Receptor Agonist, Superiority of Natural Substances versus Drugs
[+]

Target prediction and activity verification for the antidepressant action of Scutellariae baicalensis.Jan 11, 2021

Pubmed Data : J Tradit Chin Med. 2021 12 ;41(6):845-852. PMID: 34939380
Article Published Date : Jan 11, 2021
Study Type : In Vitro Study
Additional Links
Substances : Skullcap: Chinese
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

Targets and potential mechanism of Scutellaria baicalensis in treatment of primary hepatocellular carcinoma based on bioinformatics analysis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Oncol. 2022 ;2022:8762717. Epub 2022 Feb 12. PMID: 35190740
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Skullcap: Chinese
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic
[+]

The major bioactive compound found within Chinese skullcap is an iron chelator and radical scavenger. Mar 01, 2009

Pubmed Data : J Inorg Biochem. 2009 Mar;103(3):326-32. Epub 2008 Nov 19. PMID: 19108897
Article Published Date : Mar 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Iron Overload, Iron Poisoning
Additional Keywords : Iron Chelation
[+]

The mechanistic activity of Chinese skullcap may make it a useful herb for treating periodontal disease.Jun 01, 2018

Pubmed Data : Complement Ther Med. 2018 Jun ;38:11-18. Epub 2018 Mar 26. PMID: 29857875
Article Published Date : Jun 01, 2018
Study Type : Review
Additional Links
Substances : Chinese Skullcap
Diseases : Periodontal Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antibacterial Effects
Additional Keywords : Plant Extracts
[+]

The root extract of Scutellaria baicalensis Georgi promotes β cell function and protects from apoptosis by inducing autophagy.Feb 09, 2022

Pubmed Data : J Ethnopharmacol. 2022 Feb 10 ;284:114790. Epub 2021 Nov 1. PMID: 34737007
Article Published Date : Feb 09, 2022
Study Type : In Vitro Study
Additional Links
Substances : Skullcap: Chinese
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Apoptotic, Pancreato Protective Agents
Additional Keywords : Plant Extracts
[+]

Therapeutic efficacy of Scutellaria baicalensis Georgi against psoriasis-like lesions.Oct 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 Nov ;155:113798. Epub 2022 Oct 4. PMID: 36271574
Article Published Date : Oct 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Skullcap: Chinese
Diseases : Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, NF-kappaB Inhibitor, Nrf2 activation
Additional Keywords : Plant Extracts
[+]

Therapeutic potential of bioactive components from Scutellaria baicalensis in inflammatory bowel disease and colorectal cancer.Jan 18, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2023 Jan 19 ;24(3). Epub 2023 Jan 19. PMID: 36768278
Article Published Date : Jan 18, 2023
Study Type : Review
Additional Links
Substances : Skullcap: Chinese
Diseases : Colorectal Cancer, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

Whey has a chemosensitizing effect in human liver cancer cells exposed to baicalein (Chinese Skullcap). May 01, 2002

Pubmed Data : J Affect Disord. 2002 May;69(1-3):15-29. PMID: 11525598
Article Published Date : May 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap , Whey
Diseases : Liver Cancer
Pharmacological Actions : Antineoplastic Agents, Antioxidants, Apoptotic
Additional Keywords : Natural Substance Synergy
[+]

Wogonin has a synergistic effect with 5-fluorouracil, etoposide, and adriamycin to enhance chemotherapy and reverse drug resistance.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Onco Targets Ther. 2016 ;9:2935-43. Epub 2016 May 17. PMID: 27274287
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Chinese Skullcap , Wogonin
Diseases : Cancers: All
Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Apoptotic, Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Natural Substance/Drug Synergy
[+]

Wogonin, a compound found within Chinese Skullcap, significantly suppresses differentiation of leukemia cells in acute myeloid leukemia.Apr 01, 2008

Pubmed Data : Cancer Sci. 2008 Apr;99(4):689-95. PMID: 18377421
Article Published Date : Apr 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap
Diseases : Acute Myeloid Leukemia, Leukemia: Acute myelogenous leukemia (AML)
[+]

Wogonin, a compound within Chinese Skullcap, attenuates the adverse side effects of glucocorticoid-induced changes, without reducing the drug's anti-inflammatory effects.Aug 01, 2007

Pubmed Data : J Pharmacol Sci. 2007 Aug;104(4):355-65. Epub 2007 Aug 10. PMID:17690528
Article Published Date : Aug 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap , Wogonin
Diseases : Steroid-Induced Toxicity
Additional Keywords : Drug Side Effect Attenuation
[+]

Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the promyelocytic leukemia cells.Jan 01, 2010

Pubmed Data : Phytomedicine. 2010 Jan;17(1):47-54. Epub 2009 Jul 3. PMID: 19577445
Article Published Date : Jan 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap , Wogonin
Diseases : Promyelocytic leukemia
Pharmacological Actions : Apoptotic, Telomerase Inhibitor

Copyright: kazakovmaksim / 123RF Stock Photo

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