Chlorogenic Acid

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97 Diseases Researched for Chlorogenic Acid
NameACCKFocus
Hypertension323Locked
Insulin Resistance322Locked
Cognitive Decline/Dysfunction220Locked
Melanoma120Locked
Skin Cancer120Locked
Oxidative Stress1015Locked
Nonalcoholic fatty liver disease (NAFLD)314Locked
Obesity414Locked
Breast Cancer313Locked
Cardiovascular Diseases313Locked
Inflammation813Locked
Diabetes Mellitus: Type 2611Locked
Arteriosclerosis110Locked
Dyslipidemias110Locked
Fatty Liver110Locked
Hyperlipidemia110Locked
Metabolic Syndrome X110Locked
Urinary Tract Infections110Locked
Chemically-Induced Liver Damage36Locked
Colitis36Locked
Neurodegenerative Diseases35Locked
Alcohol Toxicity 24Locked
Aluminum Toxicity 34Locked
Cerebral Ischemia24Locked
Depression24Locked
Escherichia coli Infections44Locked
Hyperglycemia34Locked
Parkinson's Disease34Locked
Cardiomyopathy23Locked
Klebsiella Infections23Locked
Lung Cancer33Locked
Osteoporosis23Locked
Pseudomonas aeruginosa33Locked
Staphylococcus aureus infection23Locked
Advanced Glycation End products (AGE)22Locked
Alcoholic Liver Disease12Locked
Anxiety12Locked
Arsenic Poisoning12Locked
Atopic Dermatitis12Locked
Brain Ischemia12Locked
Cadmium Poisoning 12Locked
Carcinoma: Non-Small-Cell Lung22Locked
Chemotherapy-Induced Kidney Damage12Locked
Chemotherapy-Induced Toxicity: Gentamicin12Locked
Dermatitis12Locked
Diabetes Mellitus: Type 112Locked
Diabetes Mellitus: Type 2: Prevention12Locked
Diabetes: Oxidative Stress12Locked
Endothelial Dysfunction12Locked
Esophageal Cancer12Locked
Glaucoma12Locked
Heart Failure12Locked
High Fat Diet12Locked
Inflammatory Bowel Diseases12Locked
Ischemia12Locked
Kidney Damage12Locked
Kidney Damage: Chemically-Induced12Locked
Kidney Fibrosis12Locked
Klesiella Pneumonia Infection12Locked
Lead Poisoning12Locked
Liver Cancer22Locked
Liver Fibrosis12Locked
Memory Loss12Locked
Myocardial Fibrosis 12Locked
Osteosarcoma22Locked
Psoriasis12Locked
Spinal Cord Injuries12Locked
Testicular Injury: Chemical/Metal Induced12Locked
Ulcerative Colitis12Locked
Ultraviolet Radiation Induced Damage12Locked
Adenoviridae Infections11Locked
Alzheimer's Disease11Locked
Bacterial Infections11Locked
Brain: Oxidative Stress11Locked
Cancers: All11Locked
Candida Albicans11Locked
Colon Cancer11Locked
Coronavirus Infection11Locked
DNA damage11Locked
Dopamine Deficiency11Locked
Dysbiosis11Locked
Dysbiosis: Bifidobacteria Deficiency11Locked
Ebola Virus Infections11Locked
Hepatitis B 11Locked
Herpes Simplex Virus Type 211Locked
Histamine: Elevated11Locked
Hydrogen Peroxide Induced Toxicity11Locked
Infection: Antibiotic Resistant11Locked
Influenza A11Locked
Kidney Cancer11Locked
Lipopolysaccharide-Induced Toxicity11Locked
Malaria11Locked
Neuropathic Pain11Locked
Pancreatic Cancer11Locked
Pesticide Toxicity 11Locked
Radiation Induced Illness11Locked
Salmonella Infections11Locked
60 Pharmacological Actions Researched for Chlorogenic Acid
NameACCKFocus
Antioxidants2842Locked
Anti-Inflammatory Agents1941Locked
Neuroprotective Agents1339Locked
Chemopreventive533Locked
Hepatoprotective1028Locked
Antihypertensive Agents424Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor722Locked
Hypoglycemic Agents618Locked
Cardioprotective517Locked
Anti-Bacterial Agents616Locked
Anti-Apoptotic813Locked
Hypolipidemic313Locked
Nrf2 activation813Locked
Antiproliferative 910Locked
Insulin Sensitizers110Locked
Interleukin-6 Downregulation510Locked
Vasoprotective110Locked
Apoptotic99Locked
Interleukin-1 beta downregulation48Locked
Renoprotective48Locked
Gastrointestinal Agents47Locked
Antiviral Agents55Locked
Anti-Fibrotic24Locked
Antidepressive Agents24Locked
Antimicrobial33Locked
Cell cycle arrest33Locked
NF-kappaB Inhibitor23Locked
Vascular Endothelial Growth Factor Inhibitors33Locked
Anti-Anxiety Agents12Locked
Anti-metastatic12Locked
Anticarcinogenic Agents22Locked
Antineoplastic Agents22Locked
Autophagy Inhibitors12Locked
Chemoprotective Agents12Locked
Cyclooxygenase 2 Inhibitors12Locked
Gastroprotective12Locked
MicroRNA modulator22Locked
Osteoprotective 12Locked
Quorum Sensing Inhibition22Locked
Angiogenesis Inhibitors11Locked
Antifungal Agents11Locked
Antimalarials11Locked
Autophagy Up-regulation11Locked
Chelating Agents11Locked
Chemosensitizer11Locked
Cytoprotective11Locked
Dopaminergic11Locked
Enzyme Inhibitors11Locked
Genoprotective11Locked
Gluconeogenesis Inhibitor11Locked
Heme oxygenase-1 up-regulation11Locked
Histamine down-regulation11Locked
Hypoxia-inducible factor-1 (HIF-1) inhibitor11Locked
Immunomodulatory11Locked
Interleukin-10 upregulation11Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor11Locked
Neurominidase Inhibitor11Locked
Phase II Detoxification Enzyme Inducer11Locked
Radioprotective11Locked
Transforming growth factor beta (TGF-β) inhibitor11Locked

View the Evidence:
148 Abstracts with Chlorogenic Acid Research

[+]

The evidence suggests that chlorogenic acids intake causes statistically significant reductions in systolic and diastolic blood pressures.Jan 31, 2015

Pubmed Data : J Hum Hypertens. 2015 Feb ;29(2):77-81. Epub 2014 Jun 19. PMID: 24943289
Article Published Date : Jan 31, 2015
Study Type : Meta Analysis, Review
Additional Links
Substances : Chlorogenic Acid
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents
[+]

There is some evidence for the beneficial effects of regular coffee consumption on melanoma.Mar 31, 2016

Pubmed Data : Am J Clin Dermatol. 2016 Apr ;17(2):113-23. PMID: 26547919
Article Published Date : Mar 31, 2016
Study Type : Meta Analysis, Review
Additional Links
Substances : Chlorogenic Acid, Coffee
Diseases : Melanoma, Skin Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Factors
[+]

A combined nutraceutical showed to improve lipid and glucose metabolism, adipokines pattern, and systemic inflammation in dyslipidemic overweight subjects.Jul 31, 2019

Pubmed Data : Phytother Res. 2019 Aug ;33(8):2094-2101. Epub 2019 Jun 21. PMID: 31225673
Article Published Date : Jul 31, 2019
Study Type : Human Study
Additional Links
Substances : Artichoke, Bergamot, Chlorogenic Acid, Vitamin C
Diseases : Dyslipidemias
Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents, Hypolipidemic, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

A nutraceutical formula containing berberine, chlorogenic acid, and tocotrienols was found to improve a large number of metabolic and liver parameters in overweight subjects.Mar 28, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr J. 2015 Mar 28 ;14:30. Epub 2015 Mar 28. PMID: 25886384
Article Published Date : Mar 28, 2015
Study Type : Human Study
Additional Links
Substances : Berberine, Chlorogenic Acid, Tocotrienols
Diseases : Fatty Liver, Hyperlipidemia, Insulin Resistance
Problem Substances : Insulin
[+]

Altilix supplementation was a beneficial approach in the management of hepatic and cardiometabolic alterations in metabolic syndrome subjects.Oct 24, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Oct 25 ;11(11). Epub 2019 Oct 25. PMID: 31731527
Article Published Date : Oct 24, 2019
Study Type : Human Study
Additional Links
Substances : Chlorogenic Acid, Luteolin
Diseases : Cardiovascular Diseases, Metabolic Syndrome X, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Cardioprotective, Hepatoprotective
[+]

Bioactive yoghurt containing curcumin and chlorogenic acid reduces inflammation in postmenopausal women.Nov 01, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Nov 2 ;14(21). Epub 2022 Nov 2. PMID: 36364884
Article Published Date : Nov 01, 2022
Study Type : Human Study
Additional Links
Substances : Chlorogenic Acid, Curcumin, Yoghurt
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Black chokeberry juice lowered the incidence of Urinary tract infections by 55% and a reduction in antibiotics use in patients. May 31, 2014

Pubmed Data : Nutr Res. 2014 Jun ;34(6):518-25. Epub 2014 Jun 3. PMID: 25026919
Article Published Date : May 31, 2014
Study Type : Human Study
Additional Links
Substances : Anthocyanins, Chlorogenic Acid, Chokeberry
Diseases : Urinary Tract Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Natural Substances Versus Drugs, Proanthocyanidins
[+]

Chlorogenic acid increased insulin sensitivity and improved both anthropometric evaluations and the lipid profile.Dec 19, 2017

Pubmed Data : J Med Food. 2017 Dec 20. Epub 2017 Dec 20. PMID: 29261010
Article Published Date : Dec 19, 2017
Study Type : Human Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Insulin Resistance
Pharmacological Actions : Insulin Sensitizers
[+]

Chlorogenic acids-present in coffee, fruits, and vegetables-was associated with a lower incidence of breast cancer among postmenopausal women.Jan 21, 2020

Pubmed Data : J Acad Nutr Diet. 2020 Jan 22. Epub 2020 Jan 22. PMID: 31982373
Article Published Date : Jan 21, 2020
Study Type : Human Study
Additional Links
Substances : Chlorogenic Acid, Coffee, Fruit: All, Vegetables: All
Diseases : Breast Cancer
Pharmacological Actions : Chemopreventive
[+]

Coffee abundant in chlorogenic acids reduces abdominal fat in overweight adults.Jul 15, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Jul 16 ;11(7). Epub 2019 Jul 16. PMID: 31315279
Article Published Date : Jul 15, 2019
Study Type : Human Study
Additional Links
Substances : Chlorogenic Acid, Green Coffee Bean
Diseases : Obesity
Additional Keywords : Anti-Obesity Agents
[+]

Continuous intake of chlorogenic acids appears to improve attention and executive function among cognitive functions in mild cognitive impairment.Oct 28, 2019

Pubmed Data : J Alzheimers Dis. 2019 Oct 29. Epub 2019 Oct 29. PMID: 31683483
Article Published Date : Oct 28, 2019
Study Type : Human Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

These findings suggest that 2-week ingestion of chlorogenic acid-enriched green coffee bean extract may improve arterial stiffness.Oct 31, 2019

Pubmed Data : Int J Food Sci Nutr. 2019 Nov ;70(7):901-908. Epub 2019 Mar 25. PMID: 30907200
Article Published Date : Oct 31, 2019
Study Type : Human Study
Additional Links
Substances : Chlorogenic Acid, Green Coffee Bean
Diseases : Arteriosclerosis
Pharmacological Actions : Vasoprotective
[+]

These results allow us to conclude that maté traditional beverages are important dietary sources of chlorogenic acids.Nov 21, 2017

Pubmed Data : J Agric Food Chem. 2017 Nov 22 ;65(46):10093-10100. Epub 2017 Nov 7. PMID: 29056047
Article Published Date : Nov 21, 2017
Study Type : Human Study
Additional Links
Substances : Chlorogenic Acid, Yerba Mate
Additional Keywords : Plant Extracts
[+]

These results suggest that chlorogenic acids may improve some cognitive functions, which would help in the efficient performance of complex tasks.Sep 19, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Sep 20 ;10(10). Epub 2018 Sep 20. PMID: 30241302
Article Published Date : Sep 19, 2018
Study Type : Human Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

A combined dosage of tetrahydrocurcumin and chlorogenic acid protects against experimentally induced type 2 diabetes in rats.Aug 01, 2010

Pubmed Data : Mol Cell Biochem. 2010 Aug;341(1-2):109-17. Epub 2010 Mar 26. PMID: 20339905
Article Published Date : Aug 01, 2010
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid, Curcumin, Tetrahydrocurcumin
Diseases : Diabetes Mellitus: Type 2, Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

A natural compound mixture ameliorates psoriasis-like skin lesions.Dec 31, 2019

Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:9416962. Epub 2020 Oct 22. PMID: 33149756
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid, Emodin, Genipin, Ginsenosides
Diseases : Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.Dec 31, 2017

Pubmed Data : Int Immunopharmacol. 2018 Jan ;54:125-130. Epub 2017 Nov 9. PMID: 29128856
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Administration of chlorogenic acid alleviates spinal cord injury.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2018 Jan ;17(1):1340-1346. Epub 2017 Nov 6. PMID: 29115619
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Spinal Cord Injuries
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Analysis of anti-osteoporosis function of chlorogenic acid by gene microarray profiling in ovariectomy rat model.Jan 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Rep. 2018 08 31 ;38(4). Epub 2018 Aug 31. PMID: 30054432
Article Published Date : Jan 30, 2018
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Caffeic acid prevented dermatitis and pigmentation after UVB irradiation in mice.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Skin Pharmacol Physiol. 2017 ;30(1):24-35. Epub 2017 Feb 3. PMID: 28152530
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Caffeic Acid, Chlorogenic Acid, Coffee
Diseases : Dermatitis, Inflammation, Ultraviolet Radiation Induced Damage
Therapeutic Actions : Sunlight exposure
[+]

Cardio-protective and antioxidant properties of caffeic acid and chlorogenic acid.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Jan ;109:450-458. Epub 2018 Nov 3. PMID: 30399581
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Caffeic Acid, Chlorogenic Acid
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents, Antioxidants
[+]

Chlorogenic acid abates male reproductive dysfunction in arsenic-exposure.Nov 22, 2020

Pubmed Data : Chem Biol Interact. 2020 Nov 23:109333. Epub 2020 Nov 23. PMID: 33242462
Article Published Date : Nov 22, 2020
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Arsenic Poisoning, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Chlorogenic acid activates Nrf2/SKN-1 and prolongs the lifespan of Caenorhabditis elegans.Mar 11, 2022

Pubmed Data : J Gerontol A Biol Sci Med Sci. 2022 Mar 12. Epub 2022 Mar 12. PMID: 35279029
Article Published Date : Mar 11, 2022
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Aging
Pharmacological Actions : Antioxidants, Nrf2 activation
Additional Keywords : Gene Expression Regulation
[+]

Chlorogenic acid alleviated liver fibrosis in methionine and choline deficient diet-induced nonalcoholic steatohepatitis.Apr 22, 2022

Pubmed Data : J Nutr Biochem. 2022 Apr 23:109020. Epub 2022 Apr 23. PMID: 35472433
Article Published Date : Apr 22, 2022
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Liver Fibrosis, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Fibrotic, Hepatoprotective
[+]

Chlorogenic acid alleviates autophagy and insulin resistance by suppressing JNK pathway in a rat model of nonalcoholic fatty liver disease.May 31, 2018

Pubmed Data : J Biosci. 2018 Jun ;43(2):287-294. PMID: 29872017
Article Published Date : May 31, 2018
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Insulin Resistance, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Autophagy Inhibitors, Hypoglycemic Agents
[+]

Chlorogenic acid alleviates hyperglycemia-induced cardiac fibrosis.Nov 16, 2020

Pubmed Data : Mol Nutr Food Res. 2020 Nov 17:e2000810. Epub 2020 Nov 17. PMID: 33200558
Article Published Date : Nov 16, 2020
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Cardiomyopathy, Hyperglycemia, Myocardial Fibrosis
Pharmacological Actions : Anti-Fibrotic, Cardioprotective
[+]

Chlorogenic acid alleviates obesity and modulates gut microbiota in high-fat-fed mice.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2019 Feb ;7(2):579-588. Epub 2019 Jan 28. PMID: 30847137
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : High Fat Diet, Obesity
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Anti-Obesity Agents
[+]

Chlorogenic acid alleviates thioacetamide-induced toxicity and promotes liver development.Nov 20, 2021

Pubmed Data : Aquat Toxicol. 2021 Nov 21 ;242:106039. Epub 2021 Nov 21. PMID: 34856462
Article Published Date : Nov 20, 2021
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Hepatoprotective
[+]

Chlorogenic acid ameliorates alcohol-induced liver injuries through scavenging reactive oxygen species.Jun 30, 2018

Pubmed Data : Biochimie. 2018 Jul ;150:131-138. Epub 2018 May 19. PMID: 29787793
Article Published Date : Jun 30, 2018
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Alcohol Toxicity , Alcoholic Liver Disease, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hepatoprotective
[+]

Chlorogenic acid ameliorates colitis and alters colonic microbiota in a mouse model of dextran sulfate sodium-induced colitis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Physiol. 2019 ;10:325. Epub 2019 Mar 27. PMID: 30971953
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Chlorogenic acid ameliorates endothelial dysfunction in diabetes.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Int Med Res. 2021 Jan ;49(1):300060520985363. PMID: 33472479
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Diabetes: Oxidative Stress, Endothelial Dysfunction
Pharmacological Actions : Antioxidants, Nrf2 activation
[+]

Chlorogenic acid ameliorates experimental colitis.Oct 31, 2018

Pubmed Data : Food Chem Toxicol. 2018 Nov ;121:140-150. Epub 2018 Aug 27. PMID: 30165128
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Colitis, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents
[+]

Chlorogenic acid ameliorates high-fat and high-fructose diet-induced cognitive impairment.Feb 20, 2022

Pubmed Data : J Agric Food Chem. 2022 Feb 21. Epub 2022 Feb 21. PMID: 35188379
Article Published Date : Feb 20, 2022
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Cognitive Decline/Dysfunction, High Fat Diet, High Fructose Diet
Pharmacological Actions : Gastrointestinal Agents, Neuroprotective Agents
Additional Keywords : Gut-brain Axis
[+]

Chlorogenic acid ameliorates memory loss and hippocampal cell death after transient global ischemia.Aug 21, 2019

Pubmed Data : Eur J Neurosci. 2019 Aug 22. Epub 2019 Aug 22. PMID: 31437868
Article Published Date : Aug 21, 2019
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Brain Ischemia, Memory Loss
Pharmacological Actions : Neuroprotective Agents
[+]

Chlorogenic acid and Crataegus pinnatifida extracts prevented depressive behaviour and thereby have potential as natural antidepressants.Jun 11, 2018

Pubmed Data : Mol Nutr Food Res. 2018 Jun 12:e1800029. Epub 2018 Jun 12. PMID: 29893510
Article Published Date : Jun 11, 2018
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid, Hawthorn
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

Chlorogenic acid attenuates cadmium-induced intestinal injury in Sprague-Dawley rats.Oct 31, 2019

Pubmed Data : Food Chem Toxicol. 2019 Nov ;133:110751. Epub 2019 Aug 4. PMID: 31390532
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Cadmium Poisoning
Pharmacological Actions : Gastrointestinal Agents, Gastroprotective
Problem Substances : Cadmium
[+]

Chlorogenic acid attenuates dextran sodium sulfate-induced ulcerative colitis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2019 ;2019:6769789. Epub 2019 Apr 18. PMID: 31139644
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants
[+]

Chlorogenic acid attenuates high-carbohydrate, high-fat diet-induced cardiovascular, liver, and metabolic changes.Jan 31, 2019

Pubmed Data : Nutr Res. 2019 Feb ;62:78-88. Epub 2018 Nov 9. PMID: 30803509
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Cardiovascular Diseases, Diabetes Mellitus: Type 2
Pharmacological Actions : Cardioprotective, Hepatoprotective
[+]

Chlorogenic acid attenuates kidney ischemic/reperfusion injury.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2019 ;2019:5423703. Epub 2019 Sep 22. PMID: 31662982
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Inflammation, Ischemia, Kidney Damage, Kidney Fibrosis
Pharmacological Actions : Renoprotective
[+]

Chlorogenic acid attenuates the neuronal damage induced in alcohol exposed neonatal rat by decreasing the apoptosis of neuronal cells.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Transl Neurosci. 2017 ;8:176-181. Epub 2017 Nov 30. PMID: 29318034
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Alcohol Toxicity
Pharmacological Actions : Neuroprotective Agents
[+]

Chlorogenic acid could be a potential therapeutic to minimize sodium arsenite-induced hepatic injury.Jan 31, 2020

Pubmed Data : Mol Biol Rep. 2020 Feb ;47(2):1161-1171. Epub 2019 Dec 9. PMID: 31820315
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Apoptotic, Hepatoprotective
Problem Substances : Arsenic
[+]

Chlorogenic acid could be of benefit in glaucoma treatment. May 05, 2019

Pubmed Data : Cell Cycle. 2019 May 6. Epub 2019 May 6. PMID: 31055996
Article Published Date : May 05, 2019
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Glaucoma, Oxidative Stress
Pharmacological Actions : Antioxidants, Nrf2 activation
[+]

Chlorogenic acid decreases glutamate release from rat cortical nerve terminals by P/Q-Type Ca 2+ channel suppression.Oct 22, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2021 Oct 23 ;22(21). Epub 2021 Oct 23. PMID: 34768876
Article Published Date : Oct 22, 2021
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Neurological Conditions
Pharmacological Actions : Neuroprotective Agents
[+]

Chlorogenic acid enriched Green Coffee Ameliorated Renal InjurySep 30, 2020

Pubmed Data : Mymensingh Med J. 2020 Oct ;29(4):991-1000. PMID: 33116107
Article Published Date : Sep 30, 2020
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid, Green Coffee Bean
Diseases : Chemotherapy-Induced Kidney Damage, Chemotherapy-Induced Toxicity: Gentamicin
Pharmacological Actions : Chemoprotective Agents, Renoprotective
[+]

Chlorogenic acid has anxiolytic effects coupled with antioxidant activity.Nov 14, 2007

Pubmed Data : J Neurol Sci. 2007 Nov 15 ;262(1-2):77-84. Epub 2007 Aug 14. PMID: 17698084
Article Published Date : Nov 14, 2007
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Apple, Cherry: All Varieties, Chlorogenic Acid, Plum
Diseases : Anxiety, Neurodegenerative Diseases, Oxidative Stress
Pharmacological Actions : Anti-Anxiety Agents, Antioxidants
Additional Keywords : Plant Extracts
[+]

Chlorogenic acid has profound cardioprotective effects through inhibiting the activation of NF-κB and JNK pathway.Apr 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2019 Apr 29. Epub 2019 Apr 29. PMID: 31033175
Article Published Date : Apr 28, 2019
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Heart Failure, Inflammation
Pharmacological Actions : Cardioprotective
[+]

Chlorogenic acid improves glucose tolerance, lipid metabolism, inflammation and microbiota composition.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Endocrinol (Lausanne). 2022 ;13:1042044. Epub 2022 Nov 17. PMID: 36465648
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Inflammation, Insulin Resistance
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hypolipidemic, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Chlorogenic acid improves symptoms of inflammatory bowel disease in interleukin-10 knockout mice.Sep 30, 2020

Pubmed Data : J Med Food. 2020 Oct ;23(10):1043-1053. PMID: 33054539
Article Published Date : Sep 30, 2020
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Chlorogenic acid inhibits esophageal squamous cell carcinoma growth in vitro and in vivo.Nov 06, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Nov 7 ;121:109602. Epub 2019 Nov 7. PMID: 31707349
Article Published Date : Nov 06, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Esophageal Cancer
Pharmacological Actions : Antiproliferative
[+]

Chlorogenic acid inhibits forming of diabetes mellitus in rats induced by high-fat high-sucrose and streptozotocin.Apr 30, 2020

Pubmed Data : Pak J Pharm Sci. 2020 May ;33(3):1063-1072. PMID: 33191230
Article Published Date : Apr 30, 2020
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Diabetes Mellitus: Type 2, Diabetes Mellitus: Type 2: Prevention
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
[+]

Chlorogenic acid inhibits human glioma U373 cell progression.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2021 ;15:1369-1383. Epub 2021 Mar 30. PMID: 33833498
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Glioma
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Chlorogenic acid may have therapeutic value in type 2 diabetes. Jan 17, 1997

Pubmed Data : J Med Chem. 1997 Jan 17;40(2):137-45. PMID: 9003513
Article Published Date : Jan 17, 1997
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Diabetes Mellitus: Type 2
[+]

Chlorogenic acid might be a new anti-fibrosis agent that improves liver fibrosis.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:929. Epub 2017 Dec 19. PMID: 29311932
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic, Hepatoprotective
[+]

Chlorogenic acid modulates the ubiquitin-proteasome system in stroke animal model.Dec 20, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lab Anim Res. 2022 Dec 21 ;38(1):41. Epub 2022 Dec 21. PMID: 36539905
Article Published Date : Dec 20, 2022
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Stroke
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Chlorogenic acid prevents hyperuricemia nephropathy.Aug 10, 2022

Pubmed Data : J Agric Food Chem. 2022 Aug 11. Epub 2022 Aug 11. PMID: 35950815
Article Published Date : Aug 10, 2022
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Hyperuricemia, Nephropathy
Pharmacological Actions : Gastrointestinal Agents, Renoprotective
[+]

Chlorogenic acid prevents mice from S. aureus-induced renal abscess, resulting in a significant survival advantage.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Microbiol. 2015 ;6:1031. Epub 2015 Oct 16. PMID: 26528244
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Staphylococcus aureus infection
[+]

Chlorogenic acid protects against advanced alcoholic steatohepatitis.Nov 19, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Nov 20 ;13(11). Epub 2021 Nov 20. PMID: 34836410
Article Published Date : Nov 19, 2021
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Alcohol Toxicity , Liver Steatosis
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
[+]

Chlorogenic acid relieves lead-induced cognitive impairments and hepato-renal damage.Feb 19, 2019

Pubmed Data : Food Funct. 2019 Feb 20 ;10(2):681-690. PMID: 30657151
Article Published Date : Feb 19, 2019
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Lead Poisoning
Pharmacological Actions : Antioxidants, Hepatoprotective, Neuroprotective Agents, Renoprotective
Problem Substances : Lead
[+]

Chlorogenic acid supplementation may be favourable to avoid aluminium induced hematotoxicity and hepatotoxicity for humans.Jul 31, 2017

Pubmed Data : Chem Biol Interact. 2017 Aug 1 ;273:125-132. Epub 2017 Jun 13. PMID: 28623112
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Aluminum Toxicity
Pharmacological Actions : Anti-Apoptotic, Hepatoprotective
Problem Substances : Aluminum
[+]

Chlorogenic acid supplementation shows its therapeutic ability by reducing the oxidative stress and neuroinflammation in MPTP-intoxicated mice.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:757. Epub 2018 Aug 6. PMID: 30127737
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Chlorogenic acid, quercetin, coenzyme Q10 and silymarin protect against thioacetamide-induced acute liver toxicity.Mar 30, 2021

Pubmed Data : Life Sci. 2021 Mar 31 ;277:119460. Epub 2021 Mar 31. PMID: 33811899
Article Published Date : Mar 30, 2021
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid, Coenzyme Q10, Quercetin
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
[+]

Combined treatment of tetrahydrocurcumin and chlorogenic acid exerts potential antihyperglycemic effect on type 1 diabetic rats.Mar 01, 2010

Pubmed Data : Gen Physiol Biophys. 2010 Mar;29(1):23-30. PMID: 20371877
Article Published Date : Mar 01, 2010
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid, Curcumin
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Natural Substance Synergy
[+]

Dietary chlorogenic acid regulates gut microbiota, serum-free amino acids and colonic serotonin levels in growing pigs.Nov 14, 2017

Pubmed Data : Int J Food Sci Nutr. 2017 Nov 15:1-8. Epub 2017 Nov 15. PMID: 29141471
Article Published Date : Nov 14, 2017
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Microbiota
[+]

Different protective capability of chlorogenic acid and quercetin against indomethacin-induced gastrointestinal ulceration.Jan 06, 2023

Pubmed Data : J Pharm Pharmacol. 2023 Jan 7. Epub 2023 Jan 7. PMID: 36617303
Article Published Date : Jan 06, 2023
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid, Quercetin
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective
Problem Substances : Indomethacin
[+]

Geniposide and chlorogenic acid combination ameliorates non-alcoholic steatohepatitis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1399. Epub 2018 Dec 11. PMID: 30618733
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

In vivo protective effects of chlorogenic acid against triptolide-induced hepatotoxicity and its mechanism.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2018 Dec ;56(1):626-631. PMID: 31070533
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective, Nrf2 activation
[+]

Modulation of gut microbiota by chlorogenic acid pretreatment on rats with adrenocorticotropic hormone induced depression-like behavior.May 09, 2019

Pubmed Data : Food Funct. 2019 May 10. Epub 2019 May 10. PMID: 31073553
Article Published Date : May 09, 2019
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Neuroprotective effect of chlorogenic acid in global cerebral ischemia-reperfusion rat model.Sep 30, 2019

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2019 Oct ;392(10):1293-1309. Epub 2019 Jun 12. PMID: 31190087
Article Published Date : Sep 30, 2019
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
[+]

Pentaherbs formula can ameliorate allergic inflammation and attenuate the activation of eosinophils.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2016 ;21(4). Epub 2016 Apr 20. PMID: 27104513
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Berberine, Chlorogenic Acid, Gallic Acid
Diseases : Atopic Dermatitis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation
[+]

Protective effects of chlorogenic acid on cerebral ischemia/reperfusion injury.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2020 ;14:51-60. Epub 2020 Jan 7. PMID: 32021091
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Cerebral Ischemia
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Protective effects of rutin and chlorogenic acid against antihypoxic conditions.Aug 31, 2021

Pubmed Data : Pak J Pharm Sci. 2021 Sep ;34(5):1679-1683. PMID: 34803002
Article Published Date : Aug 31, 2021
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid, Rutin
Diseases : Hypoxia
[+]

Protective effects of α-lipoic acid and chlorogenic acid on cadmium-induced liver injury.May 28, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Animals (Basel). 2021 May 29 ;11(6). Epub 2021 May 29. PMID: 34072384
Article Published Date : May 28, 2021
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid, Chlorogenic Acid
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective
Problem Substances : Cadmium
[+]

Sustained release of chlorogenic acid-loaded nanomicelles alleviates bone loss in mouse periodontitis.Aug 16, 2022

Pubmed Data : Biomater Sci. 2022 Aug 17. Epub 2022 Aug 17. PMID: 35975567
Article Published Date : Aug 16, 2022
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Periodontitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Osteoprotective
[+]

Synergistic effect of chlorogenic acid and levofloxacin against Klebsiella pneumonia infection.Jan 16, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2020 11 17 ;10(1):20013. Epub 2020 Nov 17. PMID: 33203903
Article Published Date : Jan 16, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Klebsiella Infections, Klesiella Pneumonia Infection
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substance/Drug Synergy
[+]

The beneficial effects of coffee on diabetes may be due to the action of chlorogenic acid. Dec 31, 2011

Pubmed Data : PLoS One. 2012 ;7(3):e32718. Epub 2012 Mar 7. PMID: 22412912
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid, Coffee
Diseases : Diabetes Mellitus: Type 2
[+]

The combination of lapatinib and chlorogenic acid can effectively inhibit macrophage M2 polarization and metastasis of breast cancer.May 24, 2015

Pubmed Data : Zhejiang Da Xue Xue Bao Yi Xue Ban. 2015 May 25 ;44(5):493-499. PMID: 26713522
Article Published Date : May 24, 2015
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Breast Cancer
Pharmacological Actions : Anti-metastatic
Additional Keywords : Gene Expression Regulation
[+]

These data indicated that chlorogenic acid may play a potential treatment strategy for lead toxicity.Apr 30, 2019

Pubmed Data : Biol Trace Elem Res. 2019 May ;189(1):109-117. Epub 2018 Sep 9. PMID: 30196488
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Kidney Damage: Chemically-Induced
Pharmacological Actions : Antioxidants, Renoprotective
Problem Substances : Lead
[+]

These finding indicate that chlorogenic acid is able to be a good candidate for preventive approach for neurodegenerative disorders.Sep 30, 2018

Pubmed Data : Neurotox Res. 2018 Oct ;34(3):559-573. Epub 2018 Jul 13. PMID: 30006682
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

These results suggest that chlorogenic acid could be used to treat type 1 diabetes-induced inflammation.Dec 01, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lab Anim Res. 2022 Dec 2 ;38(1):37. Epub 2022 Dec 2. PMID: 36461118
Article Published Date : Dec 01, 2022
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The chemistry of chlorogenic acid from green coffee and its role in attenuation of obesity and diabetes Jul 06, 2020

Pubmed Data : Prep Biochem Biotechnol. 2020 Jul 7:1-10. Epub 2020 Jul 7. PMID: 32633686
Article Published Date : Jul 06, 2020
Study Type : Review
Additional Links
Substances : Chlorogenic Acid, Coffee: Green/Unroasted
Diseases : Obesity
Additional Keywords : Anti-Obesity Agents
[+]

Adaptive immunoregulation of luteolin and chlorogenic acid in lipopolysaccharide-induced interleukin-10 expression.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ci Ji Yi Xue Za Zhi. 2019 Apr-Jun;32(2):186-192. Epub 2019 Jun 24. PMID: 32269953
Article Published Date : Mar 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Luteolin
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-10 upregulation
[+]

An in vitro study of anti-inflammatory activity of standardised Andrographis paniculata extracts and pure andrographolide.Feb 06, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2015 Feb 7 ;15:18. Epub 2015 Feb 7. PMID: 25888070
Article Published Date : Feb 06, 2015
Study Type : In Vitro Study
Additional Links
Substances : Andrographis, Andrographolide, Chlorogenic Acid, Flavonoids
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Anti-cancer effects of green tea epigallocatchin-3-gallate and coffee chlorogenic acid.Oct 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Oct 5 ;25(19). Epub 2020 Oct 5. PMID: 33027981
Article Published Date : Oct 04, 2020
Study Type : Review
Additional Links
Substances : Chlorogenic Acid, EGCG (Epigallocatechin gallate)
Diseases : Cancers: All
Pharmacological Actions : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Apoptotic, MicroRNA modulator
Additional Keywords : Epigenetic Modification In Cancer
[+]

Anti-inflammatory effect of astragalin and chlorogenic acid on Escherichia coli-induced inflammation of sheep endometrial epithelium cells.Dec 31, 2019

Pubmed Data : Front Vet Sci. 2020 ;7:201. Epub 2020 Apr 30. PMID: 32426380
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Flavonoids, Moringa oleifera
Diseases : Escherichia coli Infections, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Antimicrobial activity of Tunisian quince pulp and peel polyphenolic extracts.Feb 06, 2007

Pubmed Data : J Agric Food Chem. 2007 Feb 7 ;55(3):963-9. PMID: 17263500
Article Published Date : Feb 06, 2007
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Quince
Diseases : Bacterial Infections
Pharmacological Actions : Antimicrobial, Antioxidants
Additional Keywords : Plant Extracts
[+]

Antimicrobial mechanism of reaction products of Morus notabilis polyphenol oxidases and chlorogenic acid.Jun 30, 2019

Pubmed Data : Phytochemistry. 2019 Jul ;163:1-10. Epub 2019 Apr 8. PMID: 30974396
Article Published Date : Jun 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Mulberry
Diseases : Escherichia coli Infections, Pseudomonas aeruginosa, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents, Antifungal Agents, Antimicrobial
[+]

Aronia melanocarpa fruits as a rich dietary source of chlorogenic acids and anthocyanins.Jul 14, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Jul 15 ;25(14). Epub 2020 Jul 15. PMID: 32679898
Article Published Date : Jul 14, 2020
Study Type : In Vitro Study
Additional Links
Substances : Anthocyanins, Chlorogenic Acid, Chokeberry
[+]

Beneficial effects of epigallocatechin-3- O-gallate, chlorogenic acid, resveratrol, and curcumin on neurodegenerative diseases.Jan 13, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Jan 14 ;26(2). Epub 2021 Jan 14. PMID: 33466849
Article Published Date : Jan 13, 2021
Study Type : Review
Additional Links
Substances : Chlorogenic Acid, Curcumin, EGCG (Epigallocatechin gallate), Resveratrol
Diseases : Alzheimer's Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Burdock root extract and its component chlorogenic acid have potential use in antibiofilm strategies against persistent K. pneumoniae infections.Mar 27, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Microbiol Biotechnol. 2017 Mar 28 ;27(3):542-551. PMID: 27974734
Article Published Date : Mar 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Burdock, Chlorogenic Acid
Diseases : Candida Albicans, Escherichia coli Infections, Klebsiella Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Biofilm, Plant Extracts
[+]

CGA has been shown to reduce inflammation and modulate inflammatory and neuropathic pain in animal models.Oct 20, 2019

Pubmed Data : Curr Neuropharmacol. 2019 Oct 21. Epub 2019 Oct 21. PMID: 31631820
Article Published Date : Oct 20, 2019
Study Type : Review
Additional Links
Substances : Chlorogenic Acid
Diseases : Inflammation, Neuropathic Pain
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Chlorogenic acid activates ERK1/2 and inhibits proliferation of osteosarcoma cells.Oct 09, 2019

Pubmed Data : J Cell Physiol. 2019 Oct 10. Epub 2019 Oct 10. PMID: 31602671
Article Published Date : Oct 09, 2019
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Osteosarcoma
Pharmacological Actions : Antiproliferative
[+]

Chlorogenic acid attenuates glucotoxicity in H9c2 cells.Mar 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Apr ;100:467-477. Epub 2018 Feb 23. PMID: 29477910
Article Published Date : Mar 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Advanced Glycation End products (AGE), Cardiomyopathy, Hyperglycemia
Pharmacological Actions : Antioxidants, Cardioprotective
[+]

Chlorogenic acid attenuates virulence factors and pathogenicity of Pseudomonas aeruginosa by regulating quorum sensing.Dec 31, 2018

Pubmed Data : Appl Microbiol Biotechnol. 2019 Jan ;103(2):903-915. Epub 2018 Nov 12. PMID: 30421108
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Pseudomonas aeruginosa
Pharmacological Actions : Quorum Sensing Inhibition
[+]

Chlorogenic acid can regulate theapoptosis of non-small lung cancer through Notch pathway.Aug 19, 2017

Pubmed Data : Zhongguo Fei Ai Za Zhi. 2017 Aug 20 ;20(8):555-561. PMID: 28855037
Article Published Date : Aug 19, 2017
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, MicroRNA modulator, Vascular Endothelial Growth Factor Inhibitors
[+]

Chlorogenic acid could regulate glucose metabolism by directly targeting protein kinase B.Sep 22, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Sep 23 ;10(10). Epub 2018 Sep 23. PMID: 30249058
Article Published Date : Sep 22, 2018
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Plant Extracts
[+]

Chlorogenic acid depresses cellular bioenergetics to suppress pancreatic carcinoma.Nov 29, 2020

Pubmed Data : Phytother Res. 2020 Nov 30. Epub 2020 Nov 30. PMID: 33258205
Article Published Date : Nov 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative
[+]

Chlorogenic acid exerts anti-proliferative effects and apoptosis in human colon cancer caco-2 cells.Mar 02, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 Mar 3 ;19(3). Epub 2018 Mar 3. PMID: 29510500
Article Published Date : Mar 02, 2018
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Chlorogenic acid has neuroprotective effects against aluminium-induced cytotoxicity by chelation and antioxidant activation.Jul 25, 2017

Pubmed Data : Food Funct. 2017 Jul 26. Epub 2017 Jul 26. PMID: 28745369
Article Published Date : Jul 25, 2017
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Aluminum Toxicity
Pharmacological Actions : Antioxidants, Chelating Agents, Neuroprotective Agents
Problem Substances : Aluminum
[+]

Chlorogenic acid has potential utility in the treatment of the influenza virus infection.Apr 09, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Apr 10 ;7:45723. Epub 2017 Apr 10. PMID: 28393840
Article Published Date : Apr 09, 2017
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Influenza A
Pharmacological Actions : Antiviral Agents, Neurominidase Inhibitor
Additional Keywords : Antiviral Agents, Chlorogenic Acid, Influenza A, Neurominidase Inhibitor
[+]

Chlorogenic acid improves food allergy through the AMPK/ACC/CPT-1 pathway.Nov 30, 2022

Pubmed Data : J Food Biochem. 2022 Dec ;46(12):e14505. Epub 2022 Dec 1. PMID: 36455237
Article Published Date : Nov 30, 2022
Study Type : Review
Additional Links
Substances : Chlorogenic Acid
Diseases : Food Allergies
Pharmacological Actions : Anti-Allergic Agents
[+]

Chlorogenic acid improves the regorafenib effects in human hepatocellular carcinoma cells.May 18, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 May 19 ;19(5). Epub 2018 May 19. PMID: 29783729
Article Published Date : May 18, 2018
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Liver Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Cell cycle arrest
Additional Keywords : Natural Substance/Drug Synergy
[+]

Chlorogenic acid inhibition of esophageal squamous cell carcinoma metastasis.Jun 30, 2022

Pubmed Data : Anticancer Res. 2022 Jul ;42(7):3389-3402. PMID: 35790282
Article Published Date : Jun 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Cancer Metastasis, Esophageal Cancer
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Chlorogenic acid inhibits epithelial-mesenchymal transition and invasion of breast cancer.Nov 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacol Exp Ther. 2022 Dec 1. Epub 2022 Dec 1. PMID: 36456194
Article Published Date : Nov 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Breast Cancer
Pharmacological Actions : Anti-metastatic
[+]

Chlorogenic acid inhibits osteosarcoma carcinogenesis via suppressing the STAT3/Snail pathway.May 31, 2019

Pubmed Data : J Cell Biochem. 2019 Jun ;120(6):10342-10350. Epub 2018 Dec 23. PMID: 30582213
Article Published Date : May 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Osteosarcoma
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Chemopreventive
[+]

Chlorogenic acid inhibits proliferation and induces apoptosis in A498 human kidney cancer cells.Apr 14, 2019

Pubmed Data : J Pharm Pharmacol. 2019 Apr 15. Epub 2019 Apr 15. PMID: 30989669
Article Published Date : Apr 14, 2019
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Kidney Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Chlorogenic acid may act as a chemosensitizing agent leading to cancer growth suppression.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Evid Based Integr Med. 2018 Jan-Dec;23:2515690X18789628. PMID: 30051721
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Lung Cancer
Pharmacological Actions : Chemosensitizer, Hypoxia-inducible factor-1 (HIF-1) inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

Chlorogenic acid may contribute to the polyphenolic anti-cancer effect associated with consumption of vegetables and fruits.Sep 04, 2017

Pubmed Data : Mol Cell Biochem. 2017 Sep 5. Epub 2017 Sep 5. PMID: 28875417
Article Published Date : Sep 04, 2017
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive
Additional Keywords : Cancer Stem Cells
[+]

Chlorogenic acid may provide effective defenses against oxidative stress.Nov 30, 2017

Pubmed Data : Int J Mol Med. 2017 Dec 1. Epub 2017 Dec 1. PMID: 29207051
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Hydrogen Peroxide Induced Toxicity, Oxidative Stress
[+]

Chlorogenic acid might be an effective neuroprotective compound that mitigates oxidative stress and endoplasmic reticulum stress in Parkinson's disease.Jan 14, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2019 Jan 15 ;25:453-459. Epub 2019 Jan 15. PMID: 30645211
Article Published Date : Jan 14, 2019
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Brain: Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

Chlorogenic acid prevents paraquat-induced apoptosis via Sirt1-mediated regulation of redox and mitochondrial function.May 31, 2019

Pubmed Data : Free Radic Res. 2019 Jun ;53(6):680-693. Epub 2019 Jun 4. PMID: 31106605
Article Published Date : May 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Nrf2 activation
Problem Substances : Paraquat
[+]

Chlorogenic acid promoted the Nrf2/HO-1 anti-oxidative pathway by activating p21 to prevent Dex-induced mitochondrial apoptosis in osteoblastic cells.Apr 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Free Radic Biol Med. 2019 Apr 17 ;137:1-12. Epub 2019 Apr 17. PMID: 31004750
Article Published Date : Apr 16, 2019
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
Problem Substances : Dexamethasone
[+]

Chlorogenic acid promotes autophagy and alleviates Salmonella typhimurium infection.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Dev Biol. 2020 ;8:552020. Epub 2020 Nov 5. PMID: 33240872
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Salmonella Infections
Pharmacological Actions : Anti-Bacterial Agents, Autophagy Up-regulation
[+]

Chlorogenic acid protects against aluminum toxicity.Dec 31, 2018

Pubmed Data : J Inorg Biochem. 2019 Jan ;190:113-120. Epub 2018 Nov 7. PMID: 30428426
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Aluminum Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants
[+]

Chlorogenic acid reduces plasma glucose in the oral glucose test.Apr 01, 2008

Pubmed Data : Cell Biochem Funct. 2008 Apr;26(3):320-8. PMID: 17990295
Article Published Date : Apr 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Gluconeogenesis Inhibitor
[+]

Chlorogenic acid regulates the proliferation and migration of high-grade serous ovarian cancer cells.Dec 11, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Biochim Pol. 2022 Dec 12 ;69(4):855-864. PMID: 36508480
Article Published Date : Dec 11, 2022
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Ovarian Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, MicroRNA modulator
Additional Keywords : miRNA-199
[+]

Chlorogenic acid, curcumin and beta-carotene protect against gamma-radiation-induced in vivo chromosomal damage.Jan 01, 2009

Pubmed Data : Lipids Health Dis. 2009;8:39. Epub 2009 Oct 5. PMID: 7694126
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : beta-Carotene, Carotenoids, Chlorogenic Acid, Curcumin
Diseases : DNA damage, Radiation Induced Illness
Pharmacological Actions : Genoprotective, Radioprotective
[+]

Chlorogenic acid: Potential source of natural drugs for the therapeutics of fibrosis and cancer.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Transl Oncol. 2022 Jan ;15(1):101294. Epub 2021 Nov 30. PMID: 34861551
Article Published Date : Dec 31, 2021
Study Type : Review
Additional Links
Substances : Chlorogenic Acid
Diseases : Cancers: All, Fibrosis
Pharmacological Actions : Anti-Fibrotic, Chemotherapeutic
[+]

Chlorogenic acids inhibit adipogenesis: implications of Wnt/ β-catenin signaling pathway.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Endocrinol. 2021 ;2021:2215274. Epub 2021 Nov 20. PMID: 34845409
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Obesity
Pharmacological Actions : Anti-Adipogenic
Additional Keywords : Anti-Obesity Agents
[+]

Chlorogenic-induced inhibition of non-small cancer cells occurs through regulation of histone deacetylase 6.Jul 29, 2018

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2018 Jul 30 ;64(10):134-139. Epub 2018 Jul 30. PMID: 30084806
Article Published Date : Jul 29, 2018
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Enzyme Inhibitors, Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]

Coffee and chlorogenic acid amplified specific bacterial populations could be beneficial to host health.Apr 27, 2015

Pubmed Data : Br J Nutr. 2015 Apr 28 ;113(8):1220-7. Epub 2015 Mar 26. PMID: 25809126
Article Published Date : Apr 27, 2015
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Coffee
Diseases : Dysbiosis, Dysbiosis: Bifidobacteria Deficiency
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Microbiota
[+]

Coffee contains a number of substances with anti-hepatitis B virus activity. Aug 01, 2009

Pubmed Data : Antiviral Res. 2009 Aug;83(2):186-90. Epub 2009 May 20. PMID: 19463857
Article Published Date : Aug 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Caffeic Acid, Chlorogenic Acid, Coffee, Quinic acid
Diseases : Hepatitis B
Pharmacological Actions : Antiviral Agents
[+]

Coffee contains compounds which stimulate dopamine release.Oct 13, 2011

Pubmed Data : Food Chem Toxicol. 2011 Oct 13. Epub 2011 Oct 13. PMID: 22019894
Article Published Date : Oct 13, 2011
Study Type : In Vitro Study
Additional Links
Substances : 5-hydroxytryptamides, Caffeine, Catechols, Chlorogenic Acid, Coffee, N-methylpyridinium, Pyrogallol, Trigonelline
Diseases : Dopamine Deficiency
Pharmacological Actions : Dopaminergic
[+]

Combinatorial effects of the natural products arctigenin, chlorogenic acid, and cinnamaldehyde commit oxidation assassination on breast cancer cells.Mar 19, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2022 Mar 20 ;11(3). Epub 2022 Mar 20. PMID: 35326241
Article Published Date : Mar 19, 2022
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin, Chlorogenic Acid, Cinnamaldehyde
Diseases : Breast Cancer
Pharmacological Actions : Apoptotic
[+]

Consumption of green coffee and the risk of chronic diseases. Dec 31, 2018

Pubmed Data : Crit Rev Food Sci Nutr. 2019 ;59(16):2573-2585. Epub 2018 May 3. PMID: 29624417
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Chlorogenic Acid, Green Coffee Bean
Diseases : Cardiovascular Diseases
Pharmacological Actions : Antihypertensive Agents, Antioxidants, Hypoglycemic Agents, Hypolipidemic
[+]

Effect of Lactobacillus acidophilus fermentation on the composition of chlorogenic acids and anti-hyperuricemia activity of Artemisia selengensis.Nov 13, 2022

Pubmed Data : Food Funct. 2022 Nov 14 ;13(22):11780-11793. Epub 2022 Nov 14. PMID: 36300542
Article Published Date : Nov 13, 2022
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Fermented Foods and Beverages, Lactobacillus Acidophilus, Mugwort
Diseases : Hyperuricemia
Pharmacological Actions : Uricosuric Agents
[+]

Effects of chlorogenic acid on antimicrobial, antivirulence, and anti-quorum sensing of carbapenem-resistant Klebsiella pneumoniae.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Microbiol. 2022 ;13:997310. Epub 2022 Dec 13. PMID: 36583040
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Klebsiella Infections
Pharmacological Actions : Antimicrobial, Quorum Sensing Inhibition
[+]

Green coffee extract could be useful as an adjuvant in combating multidrug resistance strains of Pseudomonas aeruginosa.May 31, 2019

Pubmed Data : Daru. 2019 Jun ;27(1):35-42. Epub 2019 Jun 12. PMID: 31187452
Article Published Date : May 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Green Coffee Bean
Diseases : Infection: Antibiotic Resistant, Pseudomonas aeruginosa
Pharmacological Actions : Antimicrobial, Quorum Sensing Inhibition
[+]

Hesperidin and chlorogenic acid synergistically inhibit the growth of breast cancer cells.Sep 09, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Life (Basel). 2021 Sep 10 ;11(9). Epub 2021 Sep 10. PMID: 34575098
Article Published Date : Sep 09, 2021
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Hesperidin
Diseases : Breast Cancer
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Natural Substance Synergy
[+]

In silico study of plant polyphenols' interactions with VP24-Ebola Virus membrane-associated protein.Dec 31, 2014

Pubmed Data : Acta Chim Slov. 2015 ;62(3):555-64. PMID: 26454589
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, EGCG (Epigallocatechin gallate), Oleuropein, Polyphenols
Diseases : Ebola Virus Infections
Pharmacological Actions : Antiviral Agents
[+]

In vitro antioxidant activities of Lonicera japonica flowering bud.Mar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacognosy Res. 2017 Apr-Jun;9(2):128-132. PMID: 28539735
Article Published Date : Mar 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Honeysuckle
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Inhibition of the SARS-CoV-2 3CL pro main protease by plant polyphenols.Mar 29, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Chem. 2022 Mar 30 ;373(Pt B):131594. Epub 2021 Nov 14. PMID: 34838409
Article Published Date : Mar 29, 2022
Study Type : In Vitro Study
Additional Links
Substances : Caffeic Acid, Chlorogenic Acid, Curcumin, EGCG (Epigallocatechin gallate), Ellagic Acid, Ferulic acid, Polyphenols, Resveratrol
Diseases : Coronavirus Infection
Pharmacological Actions : Antiviral Agents
[+]

Inhibitory activity of the flower buds of Lonicera japonica Thunb. against histamine production and L-histidine decarboxylase in human keratinocytes.Jun 16, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2014 Jun 17 ;19(6):8212-9. Epub 2014 Jun 17. PMID: 24941343
Article Published Date : Jun 16, 2014
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Honeysuckle
Diseases : Histamine: Elevated
Pharmacological Actions : Histamine down-regulation
Additional Keywords : Plant Extracts
[+]

Modulatory effect of chlorogenic acid and coffee extracts on Wnt/β-catenin pathway in colorectal cancer cells.Nov 17, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Nov 18 ;14(22). Epub 2022 Nov 18. PMID: 36432565
Article Published Date : Nov 17, 2022
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Coffee
Diseases : Colorectal Cancer
Pharmacological Actions : Chemopreventive
[+]

Natural products may interfere With SARS-CoV-2 attachment to the host cell.May 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Biomol Struct Dyn. 2020 May 5:1-10. Epub 2020 May 5. PMID: 32340551
Article Published Date : May 04, 2020
Study Type : In Vitro Study
Additional Links
Substances : Alpha Linolenic Acid, Biochanin A, Caffeic Acid, Caffeic acid phenethyl ester, Chlorogenic Acid, Cinnamaldehyde, Formononetin, Genistein, Hydroxytyrosol, Thymoquinone
Diseases : Coronavirus Infection
Pharmacological Actions : Antiviral Agents
[+]

P. major possess antiviral activities and are mainly derived from its phenolic compounds.Jun 30, 2002

Pubmed Data : Antiviral Res. 2002 Jul ;55(1):53-62. PMID: 12076751
Article Published Date : Jun 30, 2002
Study Type : In Vitro Study
Additional Links
Substances : Caffeic Acid, Chlorogenic Acid, Plantago
Diseases : Adenoviridae Infections, Herpes Simplex Virus Type 2
Pharmacological Actions : Antiviral Agents
Additional Keywords : Plant Extracts
[+]

Polyphenols as inhibitors of antibiotic resistant bacteria-mechanisms underlying rutin interference with bacterial virulence.Mar 20, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2022 Mar 21 ;15(3). Epub 2022 Mar 21. PMID: 35337182
Article Published Date : Mar 20, 2022
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Citrus naringin, Ferulic acid, Gallic Acid, Hesperidin, Naringenin , P-Coumaric Acid, Rutin
Diseases : Pseudomonas aeruginosa
Pharmacological Actions : Anti-Bacterial Agents
[+]

Polyphenols were capable of inhibiting the formation of both total fluorescent AGEs and nonfluorescent carboxymethyllysine (CML).Sep 30, 2014

Pubmed Data : Food Funct. 2014 Oct ;5(10):2656-61. Epub 2014 Sep 11. PMID: 25208810
Article Published Date : Sep 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Epicatechin, Naringenin , Phloretin, Polyphenols, Rosmarinic acid
Diseases : Advanced Glycation End products (AGE), Oxidative Stress
Pharmacological Actions : Antioxidants, Cytoprotective
[+]

Review: Antihypertensive effects and mechanisms of chlorogenic acids.Mar 31, 2012

Pubmed Data : Hypertens Res. 2012 Apr ;35(4):370-4. Epub 2011 Nov 10. PMID: 22072103
Article Published Date : Mar 31, 2012
Study Type : Review
Additional Links
Substances : Chlorogenic Acid
Diseases : Hypertension, Oxidative Stress
Pharmacological Actions : Antihypertensive Agents, Antioxidants
[+]

Study on the anticancer effect of an astragaloside and chlorogenic acid-containing herbal medicine (RLT-03) in breast cancer.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:1515081. Epub 2020 Jun 10. PMID: 32595723
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Astragaloside, Chlorogenic Acid
Diseases : Breast Cancer
Pharmacological Actions : Apoptotic, Transforming growth factor beta (TGF-β) inhibitor, Vascular Endothelial Growth Factor Inhibitors
Additional Keywords : Tumor Microenvironment
[+]

Tart cherry extract inhibits the mitochondrial apoptotic cell death elicited by airborne PM 10 in human epidermal keratinocytes.Mar 12, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2021 Mar 13 ;10(3). Epub 2021 Mar 13. PMID: 33805724
Article Published Date : Mar 12, 2021
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Kaempferol, Quercetin, Tart Cherry
Diseases : Air Pollution Linked Toxicity
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

The inhibitory mechanism of chlorogenic acid and its acylated derivatives on α-amylase and α-glucosidase.Mar 14, 2022

Pubmed Data : Food Chem. 2022 Mar 15 ;372:131334. Epub 2021 Oct 5. PMID: 34638063
Article Published Date : Mar 14, 2022
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Hyperglycemia
Pharmacological Actions : Alpha-amylase inhibitor, Alpha-glucosidase inhibitor , Hypnotics and Sedatives
[+]

The multifaceted mechanisms for coffee's anti-tumorigenic effect on liver.Oct 31, 2008

Pubmed Data : Med Hypotheses. 2008 Nov ;71(5):730-6. Epub 2008 Aug 12. PMID: 18701223
Article Published Date : Oct 31, 2008
Study Type : Review
Additional Links
Substances : Chlorogenic Acid, Coffee, Kahweol
Diseases : Liver Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antioxidants, Chemopreventive, Nrf2 activation, Phase II Detoxification Enzyme Inducer
[+]

The results evidenced the antiophidic potential of both compounds, which showed higher efficiency than antivenom serum.Mar 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 Apr ;148:112766. Epub 2022 Mar 2. PMID: 35247716
Article Published Date : Mar 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Rosemaric Acid
Diseases : Snake Bite: Venom Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective, Renoprotective
[+]

Therapeutic promises of Chlorogenic acid with special emphasis on its anti-obesity property.Jul 15, 2019

Pubmed Data : Curr Mol Pharmacol. 2019 Jul 16. Epub 2019 Jul 16. PMID: 31333144
Article Published Date : Jul 15, 2019
Study Type : Review
Additional Links
Substances : Chlorogenic Acid
Diseases : Obesity
Additional Keywords : Anti-Obesity Agents
[+]

These results demonstrate that chlorogenic acid induces bacterial apoptosis in Escherichia coli.Apr 30, 2018

Pubmed Data : Free Radic Res. 2018 May ;52(5):605-615. Epub 2018 Apr 19. PMID: 29580121
Article Published Date : Apr 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Escherichia coli Infections
Pharmacological Actions : Anti-Bacterial Agents, Apoptotic
[+]

These results suggest that chlorogenic acid ameliorates LPS-PG-induced inflammatory responses.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mediators Inflamm. 2022 ;2022:2127642. Epub 2022 Apr 9. PMID: 35437426
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Periodontal Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor
[+]

This review highlights the cellular and molecular mechanisms that explain the pharmacological benefits of consuming CGA-containing beverages.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2015 ;8(1). Epub 2015 Dec 25. PMID: 26712785
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Chlorogenic Acid
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

This study provides evidence for an antimalarial potential of caffeic acid derivatives.Jul 21, 2018

Pubmed Data : J Pharm Pharmacol. 2018 Jul 22. Epub 2018 Jul 22. PMID: 30033538
Article Published Date : Jul 21, 2018
Study Type : In Vitro Study
Additional Links
Substances : Caffeic Acid, Chlorogenic Acid
Diseases : Malaria
Pharmacological Actions : Antimalarials

Chlorogenic Acid Related Articles

Benefits of Chlorogenic Acids Found in Coffee
Written by GreenMedInfo Research Group
Intake of coffee and other foods that contain chlorogenic acids has an inverse association with obesity-related chronic diseases. New evidence also shows that these phenolic compounds may also reduce the risk of breast cancer in post-menopausal women

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