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22 Diseases Researched for Choline

Name	AC	CK
Diabetes Mellitus: Type 2	2	20
Breast Cancer	2	12
Cardiovascular Diseases	1	10
Cognitive Decline/Dysfunction	1	10
Colorectal Cancer	1	10
Colorectal Cancer: Prevention	1	10
Cystic Fibrosis	1	10
Obesity	1	10
Alcohol Toxicity	1	2
Brain Inflammation	1	2
Chemically-Induced Liver Damage	1	2
Down Syndrome	1	2
Endothelial Dysfunction	1	2
Fetal Alcoholism	1	2
Liver Damage	1	2
Nonalcoholic fatty liver disease (NAFLD)	1	2
Traumatic Brain Injury	1	2
Infant Nutrition	1	1
Liver Cancer	1	1
Neurodegenerative Diseases	1	1
Prenatal Nutrition	1	1
Hyperhomocysteinemia	1	0

11 Pharmacological Actions Researched for Choline

Name	AC	CK
Chemopreventive	2	20
Neuroprotective Agents	3	13
Anticarcinogenic Agents	1	10
Hypolipidemic	1	10
Hepatoprotective	3	6
Antioxidants	2	4
Anti-Inflammatory Agents	2	3
Interleukin-8 downregulation	1	2
Malondialdehyde Down-regulation	1	2
Tumor Necrosis Factor (TNF) Alpha Inhibitor	1	2
Prostaglandin PGE2 downregulation	1	1

Research Articles 18
Cumulative Knowledge Score 29
Overall Research Rating GOOD

View the Evidence:
18 Abstracts with Choline Research

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View the Evidence: 18 Abstracts with Choline Research

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A greater intake of choline and lutein and zeaxanthin was associated with faster performance on a cognitive flexibility task in overweight people.Jan 14, 2021

Choline, betaine, and choline-containing compounds was inversely associated with colorectal cancer risk.Dec 31, 2014

Choline-related supplements may improve status of children with Cystic FibrosisMar 01, 2007

Dietary choline and betaine consumption could significantly reduce the risk of breast cancer. Jan 31, 2013

Dietary intake of choline and phosphatidylcholine could reduce the risk of type 2 diabetes in men.Mar 19, 2020

Egg consumption in U.S. children is associated with greater daily nutrient intakes.May 21, 2019

Supplementation of magnesium and choline is more effective than either magnesium or choline alone to improve coagulation in subjects with T2DM.Aug 04, 2019

Adolescent choline supplementation can attenuate some of the behavioural deficits associated with early developmental alcohol exposure.Mar 31, 2016

Dietary choline supplementation improves behavioral, histological, and neurochemical outcomes in a rat model of traumatic brain injury.Aug 01, 2008

Hepatotoxicity and endothelial dysfunction induced by high choline diet and the protective effects of phloretin in mice.Jul 31, 2016

These results support the lifelong attentional benefits of maternal choline supplementation for Ts65Dn and 2N offspring.Nov 09, 2016

Treatment of non-alcoholic steatosis using a nutraceutical multitarget formulation.Jun 17, 2020

Ursolic acid could protect against liver damage from high intake of choline. Aug 23, 2016

Choline attenuates inflammatory hyperalgesia activating nitric oxide/cGMP/ATP-sensitive potassium channels pathway.Nov 25, 2019

Deficiency of dietary sources of methyl groups (e.g. methionine, choline, b12, folate, sam-e) reduce DNA methylation in the liver which leads to liver cancer.Aug 01, 2003

Neuroprotective effects of choline and other methyl donors.Dec 05, 2019

There is evidence of increased choline needs in pre- and postnatal health. Aug 01, 2010

Choline may prevent increased homocysteine concentrations which may reduce cardiovascular risk.Jul 01, 2005

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Choline

View the Evidence:
18 Abstracts with Choline Research