Cordyceps Militaris

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25 Diseases Researched for Cordyceps Militaris
NameACCKFocus
Oxidative Stress36Locked
Glioblastoma15Locked
Diabetes Mellitus: Type 224Locked
Bisphenol Toxicity12Locked
Cancers: All22Locked
Cerebral Ischemia12Locked
Chemotherapy-Induced Toxicity: Bleomycin12Locked
Diabetes Mellitus: Type 2: Prevention12Locked
Fatigue12Locked
Glomerulosclerosis12Locked
High Fat Diet12Locked
Inflammation22Locked
Muscle Fatigue12Locked
Osteoporosis12Locked
Acute Myeloid Leukemia11Locked
Aging11Locked
Breast Cancer11Locked
Cancer Metastasis11Locked
Carcinoma: Non-Small-Cell Lung11Locked
Colorectal Cancer11Locked
Degenerative Disk Disease11Locked
Leukemia11Locked
Lipopolysaccharide-Induced Toxicity11Locked
Liver Cancer11Locked
Parkinson's Disease11Locked
23 Pharmacological Actions Researched for Cordyceps Militaris
NameACCKFocus
Antioxidants611Locked
Anti-Inflammatory Agents57Locked
Anti-metastatic26Locked
Apoptotic66Locked
Antiproliferative 44Locked
Hypoglycemic Agents24Locked
Hypolipidemic24Locked
Neuroprotective Agents23Locked
Anti-Apoptotic12Locked
Anticholesteremic Agents12Locked
Cell cycle arrest22Locked
Chemoprotective Agents12Locked
Cytoprotective12Locked
Hepatoprotective12Locked
Immunomodulatory12Locked
Osteoprotective 12Locked
Renoprotective12Locked
Tumor Suppressor Protein p53 Upregulation22Locked
Malondialdehyde Down-regulation11Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor11Locked
NF-kappaB Inhibitor11Locked
P21 Activation11Locked
Superoxide Dismutase Up-regulation11Locked

View the Evidence:
71 Abstracts with Cordyceps Militaris Research

[+]

Beneficial Effect of Cordyceps militaris on Exercise Performance via Promoting Cellular Energy Production.Nov 08, 2020

Pubmed Data : Mycobiology. 2020 Nov 9 ;48(6):512-517. Epub 2020 Nov 9. PMID: 33312018
Article Published Date : Nov 08, 2020
Study Type : Human Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Athletic Performance
Therapeutic Actions : Exercise
[+]

Cordycepin inhibited migration of human glioblastoma cells by affecting lysosomal degradation and protein phosphatase activation.Dec 28, 2016

Pubmed Data : J Nutr Biochem. 2016 Dec 29 ;41:109-116. Epub 2016 Dec 29. PMID: 28068557
Article Published Date : Dec 28, 2016
Study Type : Human In Vitro
Additional Links
Substances : Cordyceps Militaris
Diseases : Glioblastoma
Pharmacological Actions : Anti-metastatic
[+]

A novel extract from mulberry leaves fermented with Cordyceps militaris has anti-obesity effects. Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2019 Mar ;17(3):2185-2193. Epub 2019 Jan 21. PMID: 30867704
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris, Fermented Foods and Beverages, Mulberry
Diseases : High Fat Diet, Obesity
Additional Keywords : Anti-Obesity Agents
[+]

A residue polysaccharide of C. militaris might be used as a potential antihyperlipidemic, hepatoprotective and antioxidant product.Oct 19, 2015

Pubmed Data : Carbohydr Polym. 2015 Oct 20 ;131:355-62. Epub 2015 Jun 17. PMID: 26256194
Article Published Date : Oct 19, 2015
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective, Hypolipidemic
[+]

Cordycepin exhibits a suppressive effect on T cells through inhibiting TCR signalling cascade in CFA-induced inflammation Mice model.Mar 31, 2020

Pubmed Data : Immunopharmacol Immunotoxicol. 2020 Apr ;42(2):119-127. Epub 2020 Feb 27. PMID: 32105161
Article Published Date : Mar 31, 2020
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Inflammation
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-2 Downregulation
[+]

Cordycepin inhibits pancreatic cancer cell growth.Apr 30, 2020

Pubmed Data : Chin J Nat Med. 2020 May ;18(5):345-355. PMID: 32451092
Article Published Date : Apr 30, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative
[+]

Cordycepin protects against acute pancreatitis.Jun 14, 2020

Pubmed Data : Life Sci. 2020 Jun 15 ;251:117645. Epub 2020 Apr 5. PMID: 32268154
Article Published Date : Jun 14, 2020
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Inflammation, Pancreatitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cordycepin protects renal ischemia/reperfusion injury through regulating inflammation, apoptosis, and oxidative stress.Jan 16, 2020

Pubmed Data : Acta Biochim Biophys Sin (Shanghai). 2020 Jan 17. Epub 2020 Jan 17. PMID: 31951250
Article Published Date : Jan 16, 2020
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Ischemia
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Renoprotective
[+]

Cordyceps militaris could have the protective role from cognitive impairment and progression of Alzheimer's disease.May 31, 2019

Pubmed Data : Food Sci Biotechnol. 2019 Jun ;28(3):865-872. Epub 2018 Dec 4. PMID: 31093445
Article Published Date : May 31, 2019
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents, Nitric Oxide Inhibitor
[+]

Cordyceps militaris displayed antidiabetic and antinephritic activities in diet-STZ-induced diabetic rats.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2016 ;2016:9685257. Epub 2016 May 4. PMID: 27274781
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Plant Extracts
[+]

Cordyceps militaris extract had a protective against bisphenol A induced reproductive damage.Jun 16, 2016

Pubmed Data : Syst Biol Reprod Med. 2016 Jun 17:1-9. Epub 2016 Jun 17. PMID: 27315037
Article Published Date : Jun 16, 2016
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Bisphenol Toxicity
Pharmacological Actions : Cytoprotective
Problem Substances : Bisphenol A
[+]

Cordyceps militaris fraction inhibits the invasion and metastasis of lung cancer cellsNov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2018 Dec ;16(6):6930-6939. Epub 2018 Sep 27. PMID: 30546425
Article Published Date : Nov 30, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Lung Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Cordyceps militaris fruit body extract ameliorates membranous glomerulonephritis.Apr 19, 2016

Pubmed Data : Food Funct. 2016 Apr 20 ;7(4):2006-15. PMID: 27008597
Article Published Date : Apr 19, 2016
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Glomerulosclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Renoprotective
[+]

Cordyceps militaris grown on germinated soybean suppresses KRAS-driven colorectal cancer.Dec 20, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Dec 21 ;11(1). Epub 2018 Dec 21. PMID: 30577618
Article Published Date : Dec 20, 2018
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris, Fermented Foods and Beverages
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Cordyceps militaris polysaccharides effectively improved the immune function through protection against oxidative stress.Apr 30, 2016

Pubmed Data : Int J Biol Macromol. 2016 May ;86:594-8. Epub 2016 Feb 4. PMID: 26853825
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Immunomodulatory
[+]

Cordyceps militaris polysaccharides exerted protective effects on diabetic nephropathy in mice via regulation of autophagy.Jul 31, 2019

Pubmed Data : Food Funct. 2019 Aug 1 ;10(8):5102-5114. Epub 2019 Jul 31. PMID: 31363726
Article Published Date : Jul 31, 2019
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Inflammatory Agents, Autophagy Up-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
Additional Keywords : Polysaccharides
[+]

Cordyceps militaris protected against chronic kidney disease progression.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2019 ;2019:7850863. Epub 2019 Mar 31. PMID: 31049139
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cordyceps militaris treatment significantly alleviated the severity of bleomycin-induced acute lung injury in mice.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2015 ;36(5):2003-11. Epub 2015 Jul 17. PMID: 26202360
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Chemoprotective Agents
[+]

Cordyceps showed therapeutic effects through inhibiting cerebral ischemia-induced apoptosis in the hippocampus.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Exerc Rehabil. 2016 Apr ;12(2):69-78. Epub 2016 Apr 26. PMID: 27162767
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Dietary cordycepin can prevent bone loss caused by estrogen deficiency.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015 ;2015:423869. Epub 2015 Mar 22. PMID: 25874211
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Osteoporosis, Oxidative Stress
Pharmacological Actions : Antioxidants, Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Extracts from mulberry leaves fermented with Cordyceps militaris have lipolytic effects and could be used to treat obesity. Aug 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lab Anim Res. 2017 Sep ;33(3):270-279. Epub 2017 Sep 27. PMID: 29046704
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris, Fermented Foods and Beverages, White Mulberry
Diseases : Obesity
Pharmacological Actions : Lipolytic
Additional Keywords : Anti-Obesity Agents
[+]

Fermented Cordyceps militaris extract ameliorates hepatosteatosis.Mar 12, 2019

Pubmed Data : J Med Food. 2019 Mar 13. Epub 2019 Mar 13. PMID: 30864855
Article Published Date : Mar 12, 2019
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Hepatoprotective
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Fermented Cordyceps militaris extract prevents hepatosteatosis and adipocyte hypertrophy in high fat diet-fed mice.May 05, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 May 6 ;11(5). Epub 2019 May 6. PMID: 31064103
Article Published Date : May 05, 2019
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris, Fermented Foods and Beverages
Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Hepatoprotective, Hypolipidemic
[+]

Improvement of learning and memory induced by Cordyceps polypeptide treatment and the underlying mechanism.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:9419264. Epub 2018 Mar 15. PMID: 29736181
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Learning disorders, Memory Disorders
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotective and therapeutic effect of Cordyceps militaris on ischemia-induced neuronal death and cognitive impairments.Oct 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi J Biol Sci. 2019 Nov ;26(7):1352-1357. Epub 2018 Aug 17. PMID: 31762595
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Cerebral Ischemia, Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

Polysaccharide from C. militaris has an anti-fatigue effect in mice.Dec 31, 2015

Pubmed Data : Int J Med Mushrooms. 2016 ;18(12):1083-1092. PMID: 28094746
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Muscle Fatigue
Therapeutic Actions : Exercise
Additional Keywords : Polysaccharides
[+]

Study on the effect of regulation of Cordyceps militaris polypeptide on the immune function.Jul 21, 2020

Pubmed Data : Food Funct. 2020 Jul 22 ;11(7):6066-6077. PMID: 32558840
Article Published Date : Jul 21, 2020
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions : Immunomodulatory
[+]

These results indicate that CmNo1 could be a potential and economical therapeutic agent in the treatment of HFD-induced type 2 DM through hypoglycemic activity.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Diabetes Res. 2015 ;2015:723190. Epub 2015 Jul 16. PMID: 26258146
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Diabetes Mellitus: Type 2, Diabetes Mellitus: Type 2: Prevention, High Fat Diet
Pharmacological Actions : Anticholesteremic Agents, Hypoglycemic Agents
[+]

This data provides experimental evidence in supporting clinical use of Cordyceps militarisas an effective agent against fatigue.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:174616. Epub 2015 Aug 17. PMID: 26351509
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Fatigue
Pharmacological Actions : Antioxidants
[+]

Using Cordyceps militaris extracellular polysaccharides to prevent lead-induced liver and kidney toxicity.Oct 20, 2020

Pubmed Data : Food Funct. 2020 Oct 21 ;11(10):9226-9239. PMID: 33030475
Article Published Date : Oct 20, 2020
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced
Pharmacological Actions : Antioxidants, Hepatoprotective, Nrf2 activation, Renoprotective
[+]

Polysaccharides from Cordyceps miltaris cultured at different pH: Sugar composition and antioxidant activity.Jun 19, 2020

Pubmed Data : Int J Biol Macromol. 2020 Jun 20 ;162:349-358. Epub 2020 Jun 20. PMID: 32574745
Article Published Date : Jun 19, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

A methanolic extract of C. militaris at the concentration significantly inhibited cell proliferation and induced apoptosis of NCI-H460 cells.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2015 ;20(8):13927-40. Epub 2015 Jul 31. PMID: 26263965
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, P21 Activation, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Plant Extracts
[+]

A review on the effects of current chemotherapy drugs and natural agents in treating non-small cell lung cancer.Nov 30, 2017

Pubmed Data : Biomedicine (Taipei). 2017 Dec ;7(4):23. Epub 2017 Nov 13. PMID: 29130448
Article Published Date : Nov 30, 2017
Study Type : Review
Additional Links
Substances : Berberine, Cordyceps Militaris, Resveratrol
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Chemotherapeutic
[+]

An ethanol extract of Cordyceps militaris was highly cytotoxic to human colorectal carcinoma RKO cells and inhibited the growth of tumor in xenograft model.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Daru. 2015 ;23:35. Epub 2015 Jul 4. PMID: 26141646
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation
[+]

Anti-tumor and anti-metastatic roles of cordycepin, one bioactive compound of Cordyceps militaris.Jun 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi J Biol Sci. 2018 Jul ;25(5):991-995. Epub 2018 May 14. PMID: 30108453
Article Published Date : Jun 30, 2018
Study Type : Review
Additional Links
Substances : Cordyceps Militaris
Diseases : Bladder Cancer, Liver Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative
Additional Keywords : Cancer Stem Cells, Tumor Microenvironment
[+]

Antiproliferative effects of cordycepin-rich ethanol extract from brown rice-cultivated Cordyceps militaris mycelium on breast cancer cell lines.Dec 31, 2018

Pubmed Data : Int J Med Mushrooms. 2019 ;21(7):657-669. PMID: 31679300
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Breast Cancer
Pharmacological Actions : Antioxidants, Antiproliferative
[+]

C. militaris concentrate and cordycepin exhibited significant anticancer effects through their ability to induce apoptosis in breast cancer cells.Aug 25, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2019 Aug 26 ;9(9). Epub 2019 Aug 26. PMID: 31454995
Article Published Date : Aug 25, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

C. militaris could have anti-inflammatory activity mediated by cordycepin-induced suppression of AKT.Jun 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Mag. 2015 Jul-Sep;11(43):477-85. PMID: 26246722
Article Published Date : Jun 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
[+]

C. militaris was beneficial for treatment hyperuricemia.Jan 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicines (Basel). 2019 Jan 29 ;6(1). Epub 2019 Jan 29. PMID: 30699961
Article Published Date : Jan 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Bacillus subtilis infections, Escherichia coli Infections, Hyperuricemia, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents, Antioxidants, Xanthine oxidase inhibitor
[+]

Chemical structure and inhibition on α-glucosidase of the polysaccharides from Cordyceps militaris with different developmental stages.Jan 19, 2020

Pubmed Data : Int J Biol Macromol. 2020 Jan 20 ;148:722-736. Epub 2020 Jan 20. PMID: 31972201
Article Published Date : Jan 19, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Hyperglycemia
Pharmacological Actions : Alpha-glucosidase inhibitor , Antihypertensive Agents
Additional Keywords : Polysaccharides
[+]

Comparisons of the anti-tumor activity of polysaccharides from fermented mycelia and cultivated fruiting bodies of Cordyceps militaris in vitro.May 31, 2019

Pubmed Data : Int J Biol Macromol. 2019 Jun 1 ;130:307-314. Epub 2019 Feb 27. PMID: 30825564
Article Published Date : May 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Non-Small-Cell Lung Carcinoma
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Tumor Suppressor Protein p53 Upregulation
[+]

Cordycepin can control tumor cell proliferation and also induce cancer cell apoptosis.Jul 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2015 Aug ;10(2):595-599. Epub 2015 May 27. PMID: 26622539
Article Published Date : Jul 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Cancers: All
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Cordycepin effectively resensitizes cisplatin-resistant bladder cancer cells to cisplatin.Mar 01, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2020 Mar 2 ;21(5). Epub 2020 Mar 2. PMID: 32131547
Article Published Date : Mar 01, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Bladder Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

Cordycepin induces apoptosis in human bladder cancer T24 cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Trends. 2019 ;13(4):324-333. PMID: 31527329
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Bladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase
[+]

Cordycepin inhibits cancer cell proliferation and angiogenesis in cholangiocarcinoma. Apr 30, 2020

Pubmed Data : J Pharmacol Exp Ther. 2020 May ;373(2):279-289. Epub 2020 Feb 26. PMID: 32102917
Article Published Date : Apr 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative
[+]

Cordycepin inhibits human ovarian cancer by inducing autophagy and apoptosis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(11):6890-6906. Epub 2019 Nov 15. PMID: 31814895
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Ovarian Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation
[+]

Cordycepin may be a potential treatment for intervertebral disc degeneration in the future.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PeerJ. 2016 ;4:e1992. Epub 2016 May 10. PMID: 27190710
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Degenerative Disk Disease
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Cordycepin protects PC12 cells against 6-OHDA-induced neurotoxicity.Jun 30, 2016

Pubmed Data : Biomed Pharmacother. 2016 Jul ;81:7-14. Epub 2016 Apr 6. PMID: 27261571
Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Parkinson's Disease
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents, Superoxide Dismutase Up-regulation
[+]

Cordycepin suppresses the migration and invasion of human liver cancer cells by downregulating the expression of CXCR4.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2020 Jan ;45(1):141-150. Epub 2019 Oct 31. PMID: 31746344
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Liver Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , NF-kappaB Inhibitor
[+]

Cordycepin: a bioactive metabolite of C ordyceps militaris and polyadenylation inhibitor with therapeutic potential against COVID-19.Nov 22, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Biomol Struct Dyn. 2020 Nov 23:1-8. Epub 2020 Nov 23. PMID: 33225826
Article Published Date : Nov 22, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Coronavirus Infection
Pharmacological Actions : Antiviral Agents
[+]

Cordyceps militaris contains polysaccharides which have a protective effect on mitochondria and anti-aging activity.Jan 01, 2010

Pubmed Data : Am J Chin Med. 2010;38(6):1093-106. PMID: 21061463
Article Published Date : Jan 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Aging
[+]

Cordyceps militaris exerts anticancer effect on non–small cell lung cancer.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2020 Jan-Dec;19:1534735420923756. PMID: 32456485
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Lung Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation
[+]

Cordyceps militaris fraction exhibited strong anticancer activity against oral squamous carcinoma KB cells.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Mag. 2018 Jan-Mar;14(53):116-123. Epub 2018 Feb 20. PMID: 29576711
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Oral Cancer, Squamous cell carcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Cordyceps militaris fruit body extract decreases testosterone catabolism and testosterone-stimulated prostate hypertrophy.Dec 25, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Dec 26 ;13(1). Epub 2020 Dec 26. PMID: 33375244
Article Published Date : Dec 25, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Prostatic Hyperplasia: Benign
Pharmacological Actions : Enzyme Activators
[+]

Cordyceps militaris fungus extracts-mediated nanoemulsion for improvement antioxidant, antimicrobial, and anti-inflammatory activities.Dec 03, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Dec 4 ;25(23). Epub 2020 Dec 4. PMID: 33291776
Article Published Date : Dec 03, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antimicrobial, Antioxidants
[+]

Cordyceps militaris induces immunogenic cell death and enhances antitumor immunogenic response in breast cancer.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:9053274. Epub 2020 Sep 3. PMID: 32963576
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Immunomodulatory
[+]

Cordyceps militaris possesses antitumor effects in liver cancer and breast cancer cells.May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2016 Jun ;13(6):5132-40. Epub 2016 Apr 25. PMID: 27109250
Article Published Date : May 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Breast Cancer, Liver Cancer
Pharmacological Actions : Apoptotic
[+]

Efficacy of ethyl acetate fraction of Cordyceps militaris for cancer-related fatigue.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2020 Jan-Dec;19:1534735420932635. PMID: 32571104
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Cancer: Fatigue, Liver Cancer
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Sorafenib
[+]

Gold nanoparticles with C. Militaris would be an efficient chemotherapeutic treatment against the hepatocellular carcinoma cells.Nov 30, 2019

Pubmed Data : Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):2737-2745. PMID: 31304798
Article Published Date : Nov 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris, Gold (nanoparticles)
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation
[+]

Medical mushrooms and phytochemicals represent useful approaches to target tissue invasion and metastasis as well as other hallmark areas of cancer.Apr 08, 2015

Pubmed Data : Semin Cancer Biol. 2015 Apr 9. Epub 2015 Apr 9. PMID: 25865774
Article Published Date : Apr 08, 2015
Study Type : Review
Additional Links
Substances : Agaricus Blazei, Cordyceps Militaris, Medicinal Mushrooms, Milk Thistle, Poria cocos, Reishi Mushroom
Diseases : Cancer Metastasis, Cancers: All
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Natural cordycepin induces apoptosis and suppresses metastasis in breast cancer cells.Mar 25, 2020

Pubmed Data : Food Funct. 2020 Mar 26 ;11(3):2107-2116. PMID: 32163051
Article Published Date : Mar 25, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Breast Cancer
Pharmacological Actions : Anti-metastatic, Apoptotic
[+]

Polysaccharides obtained from mycelia of Cordyceps militaris attenuated doxorubicin-induced cytotoxic effects in chemotherapy.May 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Afr Health Sci. 2019 Jun ;19(2):2156-2163. PMID: 31656500
Article Published Date : May 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Chemoprotective Agents
Additional Keywords : Polysaccharides
[+]

Protective effect of Cordyceps militaris against hydrogen peroxide-induced oxidative stress in vitro.Jul 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2019 Aug ;13(4):279-285. Epub 2019 Jul 10. PMID: 31388403
Article Published Date : Jul 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Hydrogen Peroxide Induced Toxicity
Pharmacological Actions : Antioxidants
[+]

Selenium enriched Cordyceps militaris has anti-cancer effects in non-small cell lung cancer.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Onco Targets Ther. 2019 ;12:8751-8763. Epub 2019 Oct 23. PMID: 31749621
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris, Selenium
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Structure and hypoglycemic activity of a novel exopolysaccharide of Cordyceps militaris.Dec 31, 2020

Pubmed Data : Int J Biol Macromol. 2021 Jan 1 ;166:496-508. Epub 2020 Oct 28. PMID: 33129900
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents
[+]

The extract of Cordyceps Militaris inhibited the proliferation of cisplatin-resistant A549 lung cancer cells.Jul 31, 2019

Pubmed Data : J Med Food. 2019 Aug ;22(8):823-832. Epub 2019 Jul 16. PMID: 31313945
Article Published Date : Jul 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Cancers: Drug Resistant, Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

The inhibitory effect of cordycepin on the proliferation of MCF-7 breast cancer cells, and its mechanism.Aug 22, 2019

Pubmed Data : Biomolecules. 2019 Aug 23 ;9(9). Epub 2019 Aug 23. PMID: 31450828
Article Published Date : Aug 22, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase
[+]

These results suggest that CM-mediated leukemia cell death occurs through the activation of the p38 MAPK pathway.Jul 23, 2015

Pubmed Data : Am J Chin Med. 2015 Jul 24:1-15. Epub 2015 Jul 24. PMID: 26205966
Article Published Date : Jul 23, 2015
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Leukemia
Pharmacological Actions : Apoptotic
[+]

These results suggest that cordycepin possesses a synergistic cytotoxic effect with Cordyceps militaris-mediated apoptosis in human leukemia cells.Oct 14, 2014

Pubmed Data : Phytomedicine. 2014 Oct 15 ;21(12):1516-24. Epub 2014 Aug 28. PMID: 25442260
Article Published Date : Oct 14, 2014
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Acute Myeloid Leukemia
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Natural Substance Synergy
[+]

This is the first study on the isolation of cerebrosides with anti-inflammatory activity from this TCM.Feb 23, 2016

Pubmed Data : J Agric Food Chem. 2016 Feb 24 ;64(7):1540-8. Epub 2016 Feb 15. PMID: 26853111
Article Published Date : Feb 23, 2016
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Trends in the Immunomodulatory Effects of Cordyceps militaris.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:575704. Epub 2020 Nov 30. PMID: 33328984
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Substances : Cordyceps Militaris
Pharmacological Actions : Immunomodulatory
Additional Keywords : Polysaccharides

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