Crocin

Name	AC	CK
Depression	7	29
Anxiety	4	24
Hyperglycemia	3	24
Oxidative Stress	14	23
Diabetes Mellitus: Type 2	7	22
Hyperlipidemia	1	20
Hypoglycemia	1	20
Insulin Resistance	4	16
Parkinson's Disease	9	16
Alzheimer's Disease	8	12
Inflammation	8	12
Obsessive-Compulsive Disorder	2	12
Breast Cancer	9	11
Multiple Sclerosis	2	11
Burning Mouth Syndrome	1	10
Gastric Cancer	5	10
Diabetic Nephropathy	4	8
Neurodegenerative Diseases	6	8
Obesity	4	8
Cerebral Ischemia	5	7
Pesticide Toxicity	4	7
Asthma	4	6
Breast Cancer: Triple Negative	4	6
Chemotherapy-Induced Toxicity: Doxorubicin	3	6
Diabetes: Oxidative Stress	3	6
Kidney Damage	3	6
Lipopolysaccharide-Induced Toxicity	4	6
Liver Damage	3	6
Liver Fibrosis	3	6
Memory Disorders	3	6
Neuropathic Pain	3	6
Head and Neck Cancer	1	5
Hypertension	3	5
Rheumatoid Arthritis	3	5
Bisphenol Toxicity	2	4
Brain Inflammation	2	4
Brain: Oxidative Stress	2	4
Chemically-Induced Liver Damage	2	4
Colitis	2	4
DNA damage	2	4
Diabetic Complications	2	4
Hemorrhagic Shock	2	4
Hyperalgesia	2	4
Insomnia	2	4
Ischemia	2	4
Myocardial Infarction	2	4
Nonalcoholic fatty liver disease (NAFLD)	2	4
Pulmonary Fibrosis: Bleomycin-Induced	2	4
Sleep Disorders	2	4
Testicular Injury: Chemical/Metal Induced	2	4
Alcohol Toxicity	2	3
Cancers: All	3	3
Cervical Cancer	2	3
Chronic Obstructive Pulmonary Disease	2	3
Colorectal Cancer	2	3
Diabetes Mellitus: Type 1	2	3
Lipid Peroxidation	2	3
Liver Cancer	2	3
Pancreatic Cancer	2	3
Ulcerative Colitis	2	3
Aging	1	2
Aging: Liver	1	2
Alcohol Withdrawal	1	2
Alcoholic Liver Disease	1	2
Allergic Airway Diseases	1	2
Altitude Sickness	1	2
Anorexia: Stress-Induced	1	2
Atherosclerosis	2	2
Atopic Dermatitis	1	2
Breast Cancer: Chemically-Induced	1	2
Cardiomyopathy	1	2
Cardiovascular Diseases	1	2
Chemotherapy-Induced Kidney Damage	1	2
Chemotherapy-Induced Toxicity: Cyclophosphamide	1	2
Chemotherapy-Induced Toxicity: Gentamicin	1	2
Cognitive Decline/Dysfunction	1	2
Coronary Artery Disease	1	2
Delayed Sleep Phase Disorder	1	2
Diabetes: Memory Problems	1	2
Drug Toxicity: Isoprenaline	1	2
Drug Toxicity: Methotrexate	1	2
Endothelial Dysfunction	1	2
Gestational Hypertensive	1	2
Glaucoma	2	2
Hepatic Steatosis	1	2
High Fat Diet	1	2
Hydrogen Peroxide Induced Toxicity	1	2
Hypoxia	1	2
Infertility: Male	1	2
Kidney Damage: Chemically-Induced	1	2
Kidney Diseases	1	2
Learning disorders	1	2
Leishmaniasis	2	2
Liver Damage: Drug-Induced	1	2
Liver Injury: Ischemia/reperfusion	1	2
Low Back Pain	1	2
Melanoma	1	2
Memory Disorders: Sleep Deprivation Induced	1	2
Metabolic Syndrome X	1	2
Middle Cerebral Artery Occlusion (MCAO)	1	2
Mycotoxin Toxicity	1	2
Myocardial Fibrosis	1	2
Myocardial Ischemia	1	2
Nephropathy	1	2
Nicotine/Tobacco Toxicity	1	2
Osteoarthritis	1	2
Osteoporosis	1	2
Ovarian Cancer	2	2
Pancreatitis	1	2
Periodontitis	1	2
Pesticide-Induced Toxicity: Organophosphates	1	2
Radiation	1	2
Respiratory Distress Syndrome	1	2
Schizophrenia	1	2
Traumatic Brain Injury	1	2
Acute lymphoblastic leukemia (ALL)	1	1
Aluminum Toxicity	1	1
Aspergillosis	1	1
Autoimmune Diseases	1	1
Cancers: Drug Resistant	1	1
Cancers: Multi-Drug Resistant	1	1
Cardiotoxicity: Chemotherapy-Induced	1	1
Chronic Pain	1	1
Colon Cancer	1	1
Coronavirus Infection	1	1
Dementia	1	1
Dermatitis	1	1
Diabetic Retinopathy	1	1
Endothelial Damage	1	1
Epilepsy	1	1
Eye Diseases	1	1
HIV Infections	1	1
Helicobacter Pylori Infection	1	1
Herpes Simplex Virus Type 1	1	1
Leukemia: Chronic myelogenous leukemia (CML)	1	1
Lung Cancer	1	1
Macular Degeneration	1	1
Mitochondrial Dysfunction	1	1
Oral Cancer	1	1
Plasmodium Infections	1	1
Prostate Cancer	1	1
Retinoblastoma	1	1
Skin Cancer	1	1
Smoking	1	1
Squamous cell carcinoma	1	1
Thyroid Cancer	1	1

Name	AC	CK
Antioxidants	62	118
Anti-Inflammatory Agents	54	98
Hypoglycemic Agents	8	60
Neuroprotective Agents	31	52
Hypolipidemic	4	43
Tumor Necrosis Factor (TNF) Alpha Inhibitor	14	34
Antidepressive Agents	7	29
Anti-Apoptotic	16	25
Antiproliferative	17	25
Cardioprotective	14	25
Hepatoprotective	12	24
Anti-Anxiety Agents	3	22
Apoptotic	17	20
Interleukin-6 Downregulation	11	19
Nrf2 activation	10	18
NF-kappaB Inhibitor	10	16
Renoprotective	8	16
Interleukin-1 beta downregulation	9	15
Heme oxygenase-1 up-regulation	8	13
Anti-Fibrotic	6	12
Antihypertensive Agents	2	12
Insulin Sensitizers	2	12
Anti-metastatic	7	10
Chemopreventive	7	10
Interleukin-17 downregulation	1	10
MicroRNA modulator	5	10
Analgesics	4	8
Chemoprotective Agents	4	8
Pancreato Protective Agents	4	8
Malondialdehyde Down-regulation	4	7
Chemotherapeutic	5	6
Cytoprotective	3	6
Radioprotective	3	6
Radiosensitizer	2	6
Brain-derived neurotrophic factor modulator	3	5
Wnt/β-catenin signaling pathway modulation	3	5
Anticarcinogenic Agents	3	4
Bcl-2 protein down-regulation	4	4
Chemosensitizer	4	4
Cyclooxygenase 2 Inhibitors	3	4
Interleukin-4 downregulation	2	4
interleukin-13 down-regulation	2	4
Cell cycle arrest	3	3
Superoxide Dismutase Up-regulation	2	3
Angiogenesis Inducing Agents	1	2
Anti-Asthmatic Agents	1	2
Autophagy Inhibitors	1	2
Autophagy Up-regulation	1	2
Catalase Up-Regulation	1	2
Fertility Agents: Male	1	2
Gastroprotective	1	2
Immunomodulatory	2	2
Interferon Gamma Reducer	1	2
Interleukin-10 downregulation	1	2
Interleukin-5 downregulation	1	2
Matrix Metalloproteinase-7 (MMP-7) Inhibitor	1	2
Multidrug Resistance Gene Modulators	2	2
Osteoprotective	1	2
Postaglandin PGE2 downregulation	2	2
Prophylactic Agents	1	2
SIRT1 Activator	1	2
Telomerase Inhibitor	2	2
Transforming growth factor beta (TGF-β) inhibitor	1	2
Tumor Suppressor Protein p53 Upregulation	2	2
Vascular Endothelial Growth Factor A Enhancer	1	2
Angiogenesis Inhibitors	1	1
Angiotensin-Converting Enzyme Inhibitors	1	1
Anti-Bacterial Agents	1	1
Antineoplastic Agents	1	1
Antinoceceptive	1	1
Antiparasitic Agents	1	1
Antiviral Agents	1	1
Caspase-3 Activation	1	1
Cyclin D1 Down-Regulation	1	1
Interleukin-12 downregulation	1	1
Leishmanicidal	1	1
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	1
Matrix metalloproteinase-9 (MMP-9) inhibitor	1	1
STAT3 Inhibitor	1	1
Vasodilator Agents	1	1

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Pharm Res. 2017 ;16(1):230-237. PMID: 28496478

Article Published Date : Dec 31, 2016

Study Type : Human In Vitro

Additional Links

Substances : Crocin

Diseases : Head and Neck Cancer

Pharmacological Actions : Radiosensitizer

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Pathogenesis and anti-proliferation mechanisms of crocin in human gastric carcinoma cells.Dec 31, 2019

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Pubmed Data : Int J Fertil Steril. 2020 Jan ;13(4):307-314. Epub 2019 Nov 11. PMID: 31710192

Article Published Date : Dec 31, 2019

Study Type : Animal Study

Additional Links

Substances : Crocin

Diseases : Infertility: Male, Oxidative Stress, Pesticide Toxicity

Pharmacological Actions : Antioxidants

Problem Substances : Paraquat

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Ameliorative effects of crocin on paraquat-induced oxidative stress in testis.Nov 30, 2019

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Pubmed Data : Int J Reprod Biomed (Yazd). 2019 Dec ;17(11):807-818. Epub 2019 Dec 26. PMID: 31911963

Article Published Date : Nov 30, 2019

Study Type : Animal Study

Additional Links

Substances : Crocin

Diseases : Pesticide Toxicity , Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Malondialdehyde Down-regulation

Problem Substances : Paraquat

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Ameliorative effects of crocin on tartrazine dye-induced pancreatic adverse effects.Aug 31, 2020

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Pubmed Data : Environ Sci Pollut Res Int. 2020 Sep 1. Epub 2020 Sep 1. PMID: 32870427

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Pubmed Data : Pharmacol Rep. 2019 Aug ;71(4):746-752. Epub 2019 Apr 16. PMID: 31220735

Article Published Date : Jul 31, 2019

Study Type : Animal Study

Additional Links

Substances : Crocin

Diseases : Drug Toxicity: Methotrexate, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Problem Substances : Methotrexate

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Crocin and crocetin showed a significant protective effect against the N-methyl-N-nitrosourea induced breast cancer in rats.Mar 31, 2017

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Pubmed Data : Drug Chem Toxicol. 2019 Feb 3:1-8. Epub 2019 Feb 3. PMID: 30714419

Article Published Date : Feb 02, 2019

Study Type : Animal Study

Additional Links

Substances : Crocin

Diseases : Colitis

Pharmacological Actions : Anti-Inflammatory Agents

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Crocin at a dose of 60 mg/kg for six weeks could be effective in preventing nitrosative stress in hemiparkinsonian rats.Oct 31, 2016

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Pubmed Data : J Diabetes Metab Disord. 2020 Dec ;19(2):1517-1525. Epub 2020 Nov 18. PMID: 33553037

Article Published Date : Nov 30, 2020

Study Type : Animal Study

Additional Links

Substances : Crocin

Diseases : Myocardial Infarction

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective

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Crocin can improve oxidative stress in pancreatic cells by potentiating the anti-oxidant defense system.May 31, 2019

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Pubmed Data : Adv Exp Med Biol. 2021 ;1328:275-285. PMID: 34981484

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Carotenoids, Crocin

Diseases : Diabetes: Oxidative Stress

Pharmacological Actions : Antioxidants, Superoxide Dismutase Up-regulation

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Crocin improves insulin sensitivity and ameliorates adiposity.Dec 31, 2019

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Pubmed Data : Biomed Res Int. 2020 ;2020:9136282. Epub 2020 Jun 6. PMID: 32596392

Article Published Date : Dec 31, 2019

Study Type : Animal Study

Additional Links

Substances : Crocin

Diseases : Insulin Resistance, Obesity

Pharmacological Actions : Insulin Sensitizers

Additional Keywords : Anti-Obesity Agents

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Crocin improves nicotine-induced adverse effects on reproductive parameters in male mice.Mar 31, 2016

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Pubmed Data : J Exp Pharmacol. 2020 ;12:97-106. Epub 2020 Apr 28. PMID: 32431552

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Pubmed Data : Nutrients. 2020 06 26 ;12(6). Epub 2020 Jun 26. PMID: 32604971

Article Published Date : Jan 25, 2020

Study Type : Animal Study

Additional Links

Substances : Crocin

Diseases : Liver Damage, Pancreatic Cancer, Radiation

Pharmacological Actions : Radioprotective

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Effects of crocin on spatial or aversive learning and memory impairments induced by lipopolysaccharide.Dec 31, 2020

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Pubmed Data : Avicenna J Phytomed. 2021 Jan-Feb;11(1):79-90. PMID: 33628722

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Crocin

Diseases : Learning disorders, Lipopolysaccharide-Induced Toxicity, Memory Disorders

Pharmacological Actions : Neuroprotective Agents

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Exercise and crocin prevent adolescent-stress induced impairment of spatial navigation and dendritic retraction in the hippocampal CA3 area.Feb 28, 2021

Pubmed Data : Hum Exp Toxicol. 2020 Oct 6:960327120954521. Epub 2020 Oct 6. PMID: 33021114

Article Published Date : Oct 05, 2020

Study Type : Animal Study

Additional Links

Substances : Crocin, Quercetin

Diseases : Diabetes Mellitus: Type 2, Kidney Damage, Obesity

Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic, Renoprotective

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Saffron (Crocus sativus) aqueous extract and its constituent crocin reduces stress-induced anorexia in mice.Dec 01, 2011

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Pubmed Data : Phytother Res. 2011 Dec ;25(12):1833-8. Epub 2011 Apr 19. PMID: 21503997

Article Published Date : Dec 01, 2011

Study Type : Animal Study

Additional Links

Substances : Crocin, Saffron

Diseases : Anorexia: Stress-Induced

Additional Keywords : Plant Extracts

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Saffron and its active constituent crocin can prevent chronic stress-induced oxidative stress damage of the brain, liver and kidneys.Nov 30, 2014

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Additional Keywords : Cardioprotective, Cardiovascular Diseases, Crocin, exercise, MicroRNA modulator

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Crocin: A fighter against inflammation and pain.Jul 04, 2020

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Pubmed Data : Food Chem Toxicol. 2020 Jul 5 ;143:111521. Epub 2020 Jul 5. PMID: 32640351

Article Published Date : Jul 04, 2020

Study Type : Review

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Substances : Crocin

Diseases : Chronic Pain, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Antinoceceptive , NF-kappaB Inhibitor

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Pubmed Data : J Thorac Dis. 2019 Nov ;11(11):4464-4473. PMID: 31903234

Article Published Date : Oct 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Crocin

Diseases : Breast Cancer, Breast Cancer: Triple Negative

Pharmacological Actions : Angiogenesis Inhibitors, Apoptotic, Cell cycle arrest

Additional Keywords : Dose Response

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Beneficial effects of crocin against depression.Dec 31, 2019

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Pubmed Data : Anticancer Agents Med Chem. 2018 Dec 30. Epub 2018 Dec 30. PMID: 30599111

Article Published Date : Dec 29, 2018

Study Type : Review

Additional Links

Substances : Crocetin, Crocin, Saffron

Diseases : Cancers: All

Pharmacological Actions : Chemopreventive, Chemotherapeutic

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Crocetin and crocins activate different mechanisms involved in the vasoconstriction pathway in hypertension.Dec 31, 2014

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Pubmed Data : Curr Drug Deliv. 2018 ;15(5):698-704. PMID: 29189153

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Pubmed Data : West Indian Med J. 2016 Apr 18. Epub 2016 Apr 18. PMID: 27398676

Article Published Date : Apr 17, 2016

Study Type : In Vitro Study

Additional Links

Substances : Crocin

Diseases : Acute lymphoblastic leukemia (ALL)

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Dose Response

[+]

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Pubmed Data : Asian Pac J Cancer Prev. 2020 07 1 ;21(7):1959-1967. Epub 2020 Jul 1. PMID: 32711421

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Pubmed Data : J Pharm Pharmacol. 2021 Feb 1. Epub 2021 Feb 1. PMID: 33793778

Article Published Date : Jan 31, 2021

Study Type : In Vitro Study

Additional Links

Substances : Crocin

Diseases : Aluminum Toxicity , Oxidative Stress

Pharmacological Actions : Antioxidants, Cardioprotective

Problem Substances : Aluminum

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Basic Med Sci. 2019 Apr ;22(4):334-344. PMID: 31223464

Article Published Date : Mar 31, 2019

Study Type : Review

Additional Links

Substances : Crocetin, Crocin, Saffron

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Immunomodulatory, Interleukin-12 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor

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In vitro antileishmanial effects of saffron compounds, crocin and stigmasterol, on Iranian strain of Leishmania major.Dec 31, 2020

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Pubmed Data : Iran J Parasitol. 2021 Jan-Mar;16(1):151-158. PMID: 33786057

Article Published Date : Dec 31, 2020

Study Type : In Vitro Study

Additional Links

Substances : Crocin, Saffron, Stigmasterol

Diseases : Leishmaniasis

Pharmacological Actions : Leishmanicidal

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View the Evidence: 215 Abstracts with Crocin Research

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Saffron and crocin may modulate the serum lipid profile in patient with metabolic disorders.Feb 03, 2020

The effect of crocin supplementation on lipid concentrations and fasting blood glucose.Jul 31, 2020

Crocin considerably seems to be effective for relieving symptoms of CIPN in cancer patients receiving chemotherapy agents.Aug 10, 2021

The findings indicate that crocin supplementation can improve glycemic control and insulin resistance in patients with T2D.Dec 31, 2019

A pilot study of the effects of crocin on high-density lipoprotein cholesterol uptake capacity in patients with metabolic syndrome.Oct 04, 2021

Crocin alleviates cognitive impairment associated with atherosclerosis.Jan 26, 2022

Crocin can be considered for treatment of burning mouth syndrome.Oct 31, 2019

Crocin is effective in treatment of patients with mild to moderate OCD with possibly fewer adverse effects compared to fluoxetine.Feb 17, 2021

Inflammatory markers response to crocin supplementation in patients with type 2 diabetes mellitus.Apr 14, 2021

These results demonstrated the effect of crocin in depression and could be administered in treatment of MDD patients.Mar 14, 2015

These results suggest the beneficial and therapeutic effects of crocin in multiple sclerosis.Oct 15, 2019

Crocin can be considered as a potential drug and sensitizer in cancer treatment. Dec 31, 2016

Pathogenesis and anti-proliferation mechanisms of crocin in human gastric carcinoma cells.Dec 31, 2019

Crocin ameliorates oxidative stress and suppresses renal damage in streptozotocin induced diabetic male rats.Aug 23, 2020

Administering crocin ameliorates anxiety-like behaviors and reduces the inflammatory response in amyloid-beta induced neurotoxicity.Mar 07, 2021

Administration of crocin reduced d-galactose-induced aging.Dec 31, 2017

Ameliorative effect of crocin on sperm parameters and in vitro fertilization in mice under oxidative stress induced by paraquat.Dec 31, 2019

Ameliorative effects of crocin on paraquat-induced oxidative stress in testis.Nov 30, 2019

Ameliorative effects of crocin on tartrazine dye-induced pancreatic adverse effects.Aug 31, 2020

Anti-metastatic properties of a potent herbal combination in cell and mice models of triple negative breast cancer.Feb 14, 2020

Antidepressant activity of crocin-I is associated with amelioration of neuroinflammation and attenuates oxidative damage induced by corticosterone.Oct 11, 2019

Antifibrotic effects of crocin on thioacetamide-induced liver fibrosis in mice.Apr 30, 2018

Antioxidant and anti-inflammatory effects of crocin ameliorate doxorubicin-induced nephrotoxicity.Dec 31, 2020

Cognitive protective mechanism of crocin pretreatment in rat submitted to acute high-altitude hypoxia exposure.Dec 31, 2019

Crocetin and crocin are potential natural biomedicines for the management of diseases associated with abnormal blood vessel growth.Dec 31, 2020

Crocin administration could protect the liver damage induced by morphine.Feb 29, 2016

Crocin administration may reduce inflammation-driven tissue damage in patients with hemorrhagic shock.Apr 27, 2017

Crocin alleviates lipopolysaccharide-induced acute respiratory distress syndrome.Jan 09, 2020

Crocin alleviates the inflammation and oxidative stress responses associated with diabetic nephropathy.Apr 25, 2021

Crocin ameliorates atherosclerosis.Dec 31, 2021

Crocin ameliorates atopic dermatitis symptoms by down regulation of the Th2 cells-mediated immune response.Nov 01, 2018

Crocin ameliorates chronic obstructive pulmonary disease-induced depression.Sep 02, 2019

Crocin ameliorates hepatic steatosis through activation of AMPK signalling.Jan 07, 2019

Crocin ameliorates methotrexate-induced liver injury via inhibition of oxidative stress and inflammation.Jul 31, 2019

Crocin and crocetin showed a significant protective effect against the N-methyl-N-nitrosourea induced breast cancer in rats.Mar 31, 2017

Crocin and crocetin significantly increased the total time of non-rapid eye movement (non-REM) sleep after the administration.Jan 31, 2012

Crocin and Metformin suppress metastatic breast cancer progression.Apr 29, 2021

Crocin and voluntary exercise promote heart angiogenesis through Akt and ERK1/2 signalling in type 2 diabetic rats.Dec 31, 2017

Crocin as a novel therapeutic agent against colitis.Feb 02, 2019

Crocin at a dose of 60 mg/kg for six weeks could be effective in preventing nitrosative stress in hemiparkinsonian rats.Oct 31, 2016

Crocin attenuates CCl 4-induced liver fibrosis via PPAR-γ mediated modulation of inflammation and fibrogenesis in rats.Nov 30, 2020

Crocin attenuates cyclophosphamide induced testicular toxicity by preserving glutathione redox system.Apr 30, 2018

Crocin attenuates inflammation of lung tissue in ovalbumin-sensitized mice.Nov 30, 2021

Crocin attenuates isoprenaline-induced myocardial fibrosis.Aug 06, 2019

Crocin attenuates lung inflammation and pulmonary vascular dysfunction in a rat model of bleomycin-induced pulmonary fibrosis.Aug 25, 2019

Crocin attenuates metabolic syndrome-induced osteoporosis.Jun 30, 2019

Crocin attenuates osteoarthritis symptoms through alleviating oxidative stress and inflammation.Aug 06, 2017

Crocin attenuates oxidative and inflammatory stress-related periodontitis in cardiac tissues.May 10, 2021

Crocin attenuates oxidative stress and inflammation in myocardial infarction induced by isoprenaline.Nov 30, 2020

Crocin can improve oxidative stress in pancreatic cells by potentiating the anti-oxidant defense system.May 31, 2019

Crocin can improve the synaptic loss and neuronal death.Jun 09, 2020

Crocin combined with voluntary exercise improved insulin resistance and reduced glucose levels in diabetic rats.Apr 18, 2016

Crocin contributed to the alleviation of some complications of diabetes.Nov 30, 2020

Crocin could attenuate hyperalgesia induced by sleep deprivation.Apr 30, 2020

Crocin could be potentially used as an adjuvant treatment in combination with Dox to reduce cardiotoxicity.Dec 31, 2020

Crocin could contribute to the development of phytotherapeutic approaches in the treatment of obesity and diabetes.Nov 16, 2016

Crocin could significantly decrease the side effects caused by cyclophosphamide chemotherapy in mice ovarian tissue.Dec 31, 2020

Crocin demonstrates good prospects in the treatment of Alzheimer's disease through the oxidative stress associated apoptosis signalling pathway.Dec 17, 2018

Crocin exhibits an antihypertensive effect in a rat model of gestational hypertension and activates the Nrf-2/HO-1 signaling pathway.Jan 12, 2021

Crocin had a superior effect compared to sitagliptin on blood sugar level, β-islets diameter and insulin immune-reactivity.Jul 30, 2019

Crocin has a cardioprotective effect against DOX-induced cardiomayopathy.Mar 04, 2016

Crocin has a paradoxical protective effect by regulating both the induction and inhibition of autophagy in ischemia and reperfusion injury.Apr 23, 2016

Crocin has a protective effect of on gastric mucosal lesions induced by ischemia-reperfusion injury in rats.Dec 31, 2015

Crocin has a protective effect on diabetes induced oxidative stress in testicular tissue.Dec 31, 2020

Crocin has a renoprotective effects against the development of oxidative stress and inflammation in the kidney of old rats.Jun 08, 2016

Crocin has a role in attenuation of induced ulcerative colitis in rats.Jan 31, 2019

Crocin has anti-inflammatory and protective effects in ischemia-reperfusion induced renal injuries.Jun 30, 2017

Crocin has exerted neuroprotective effects in the rat model of MK-801-elicited schizophrenia.Sep 29, 2020

Crocin has potential for use as a therapuetic strategy in the treatment of lower back pain. Oct 31, 2015

Crocin has protective activities against ethanol toxic effects in the liver and kidney.Dec 31, 2019

Crocin has protective effects against gentamicin-induced nephrotoxicity in rats.Feb 29, 2016

Crocin improved memory under unpredictable stress conditions.Dec 31, 2017

Crocin

View the Evidence:
215 Abstracts with Crocin Research