Cruciferous Vegetables

Name	AC	CK
Prostate Cancer: Prevention	7	138
Breast Cancer	52	114
Oxidative Stress	48	113
Prostate Cancer	42	75
Inflammation	27	68
Lung Cancer	24	64
Cancers: All	30	59
Pancreatic Cancer	22	59
Bladder Cancer	16	47
Ovarian Cancer	10	44
Diabetes Mellitus: Type 2: Prevention	2	40
Diabetes Mellitus: Type 2	16	38
Colon Cancer	18	37
Breast Cancer: Triple Negative	10	36
Autism Spectrum Disorders	6	33
Colorectal Cancer	8	33
Cardiovascular Disease: Prevention	3	31
DNA damage	10	31
Liver Cancer	20	27
Melanoma	13	27
Insulin Resistance	7	25
Lung Cancer: Prevention	4	23
Air Pollution Linked Toxicity	4	22
Systemic Lupus Erythematosus	3	22
Breast engorgement	2	20
Cancers: Drug Resistant	8	20
Cognitive Decline/Dysfunction	6	20
Digestive System Neoplasms	1	20
Glaucoma	1	20
Kidney Cancer: Prevention	1	20
Non-Hodgkin Lymphoma	1	20
Cardiovascular Diseases	9	19
Lipopolysaccharide-Induced Toxicity	13	18
Aging	3	17
Cancer Metastasis	11	17
Helicobacter Pylori Infection	5	17
Leukemia	7	17
Chemotherapy-Induced Toxicity: Cisplatin	7	16
Obesity	9	16
Breast Cancer: Prevention	4	15
Atherosclerosis	3	14
Alzheimer's Disease	6	13
Asthma	2	12
Autism	2	12
Chemotherapy-Induced Toxicity: Doxorubicin	8	12
Diabetes Mellitus: Type 1	6	12
Diesel Exhaust Particle Toxicity	3	12
Fatty Liver	2	12
Glutathione Deficiency	3	12
Hypercholesterolemia	2	12
Smoking	2	12
HDL: Low	2	11
Nasopharyngeal Cancer	7	11
Schizophrenia	2	11
Skin Diseases	2	11
Stomach Cancer	2	11
Anemia: Sickle Cell	1	10
Benzene Toxicity	1	10
Bladder Degeneration	1	10
COPD	1	10
Cholesterol: High	1	10
Cystic Fibrosis	1	10
Esophageal Cancer	1	10
Estrogen Dysregulation: 2/4/16 hydroxyestrone ratios	1	10
Fibroids: Uterine	1	10
Gastritis	1	10
High Cholesterol	1	10
Hyperinsulinism	1	10
Kidney Cancer	1	10
Lung Diseases	1	10
Lupus Erythematosus: Systemic	1	10
Magnesium Deficiency	1	10
Metabolic Syndrome X	1	10
Prostate: PSA Doubling	1	10
Psychiatric Disorders	1	10
Pulmonary Fibrosis	1	10
Radical Prostatectomy	1	10
Respiratory Diseases	1	10
Stroke: Ischemic	1	10
Wound Healing	1	10
Cadmium Poisoning	4	9
Cervical Cancer	7	9
Gastric Cancer	4	9
Ischemia	5	9
Cancers	4	8
Chemically-Induced Liver Damage	5	8
Endothelial Dysfunction	3	8
Neurodegenerative Diseases	6	8
Advanced Glycation End products (AGE)	4	7
Cancer Stem Cells	6	7
Cerebral Ischemia	4	7
Hypoxia	5	7
Skin Cancer	6	7
Adenomatous Polyposis Coli	3	6
Alcohol Toxicity	3	6
Breast Cancer: Lung Metastasis	2	6
Liver Damage	4	6
Liver Fibrosis	4	6
Parkinson's Disease	5	6
Skin Cancer: Prevention	3	6
Benzo[a]pyrene-induced Toxicity	4	5
Brain Damage	3	5
Brain Inflammation	3	5
Breast Cancer: Estrogen	1	5
Carcinoma: Non-Small-Cell Lung	4	5
Colorectal Cancer: Prevention	1	5
Diabetes: Oxidative Stress	3	5
Endothelial Damage	1	5
Female	1	5
Fetal Alcoholism	1	5
Gastric Cancer: Prevention	1	5
Glioblastoma	4	5
Immune Disorders: Low Immune Function	3	5
Insulin Disorders	1	5
Lipid Peroxidation	1	5
Liver Damage: Aflatoxin-Induced	3	5
Rheumatoid Arthritis	3	5
Acetaminophen (Tylenol) Toxicity	2	4
Aflatoxicosis	3	4
Aspirin-Induced Toxicity	2	4
Autoimmune Diseases	2	4
Brain Injury: Traumatic	2	4
Brain: Microglial Activation	2	4
Breast Cancer: Bone Metastasis	1	4
Breast Cancer: Metastatic	3	4
Cancers: Multi-Drug Resistant	2	4
Cardiomyopathy	2	4
Cervical Dysplasia	2	4
Depression	2	4
Diabetic Complications	2	4
Dioxin Toxicity	1	4
Furan Toxicity	1	4
Head and Neck Cancer	4	4
High Fat Diet	2	4
Hydrogen Peroxide Induced Toxicity	4	4
Intestinal Polyps	2	4
Muscle Damage: Exercise-Induced	2	4
NSAID-induced toxicity	2	4
Nicotine/Tobacco Toxicity	2	4
Organ Transplantation: Pancreatic Islet Cells	2	4
Osteosarcoma	3	4
Spinal Cord Injuries	2	4
Stroke	2	4
Traumatic Brain Injury	2	4
Acute Myeloid Leukemia	2	3
Aging Skin	2	3
Bacterial Infections and Mycoses	2	3
Blood-Brain-Barrier Disorders	2	3
Brain Cancer	3	3
Chemotherapy-Induced Toxicity	2	3
Coronavirus Infection	2	3
Diabetes Mellitus: Type 1: Prevention	2	3
Diabetic Nephropathy	2	3
Drug-Induced Toxicity: Indomethacin	2	3
Gastric Ulcer	2	3
Glioma	3	3
Hyperglycemia	2	3
Intestinal Diseases	2	3
Liver Cancer: Prevention	2	3
Liver Disease	2	3
Low Disorders: Low TH1	2	3
Melanoma: Metastatic	2	3
Multiple Myeloma	2	3
Multiple Sclerosis	2	3
Myocardial Ischemia	2	3
Oral Cancer	2	3
Petroleum Exposure And Toxicity	2	3
Polycyclic aromatic hydrocarbon (PAH) toxicity	2	3
Skin Diseases: Photo-Aging	2	3
Tumors	2	3
Acute lymphoblastic leukemia (ALL)	1	2
Aging: Heart	1	2
Alcoholic Liver Disease	1	2
Amphetamine Addiction/Withdrawal	1	2
Anxiety Disorders	1	2
Atopic Dermatitis	1	2
Bisphenol Toxicity	1	2
Bladder Dysfunction	1	2
Bladder Outlet Obstruction	1	2
Brain Edema	1	2
Brain Hypoxia	2	2
Breast Cancer: BRCA1	2	2
C-Reactive Protein	1	2
Carbon Monoxide Poisoning	1	2
Cerebral Stroke	1	2
Chagas Disease	1	2
Chemical Exposure	1	2
Chemical Weapon Agent Injury	1	2
Chronic Kidney Disease (CKD)	1	2
Chronic Pain	1	2
Citrobacter Infection	1	2
Clostridium Infections	1	2
Colitis	1	2
Depressive Disorder	1	2
Diabetes: Cognitive Dysfunction	1	2
Diabetes: Kidney Function	1	2
Diabetes: Memory Problems	1	2
Drug Toxicity: Methotrexate	1	2
Duchenne's Muscular Dystrophy	1	2
Dysbiosis	1	2
Dyslipidemias	1	2
Endometriosis	1	2
Epstein-Barr Virus Infections	1	2
Escherichia coli Infections	1	2
Estrogen Dominance	2	2
Food Allergies	1	2
Fungal Infection	1	2
Gastrointestinal Cancer	1	2
Gout	1	2
Gram-Positive Bacterial Infections	2	2
Heart Failure	1	2
Heavy Metal Toxicity	1	2
High-Grade Prostatic Intraepithelial Neoplastic Lesions	1	2
Hyperlipidemia	1	2
Hypertension	1	2
Hypoglycemia	2	2
Hypogonadism	1	2
Immune Dysregulation: TH1/TH2 imbalance	1	2
Infertility: Male	1	2
Intoxication	1	2
Kidney Diseases	1	2
Laryngeal Cancer	1	2
Lead Poisoning	1	2
Light Sensitivity	1	2
Liver Steatosis	1	2
Low Immune Function: Natural Killer Cells	1	2
Malathion Toxicity	1	2
Memory Disorders	1	2
Mercury Poisoning	1	2
Metabolic Diseases	1	2
Mitochondrial Dysfunction	1	2
Muscle Fatigue	1	2
Muscle Soreness	1	2
Musculoskeletal Diseases	1	2
Myocardial Infarction	1	2
Nephropathy	1	2
Neurologic Disorders	1	2
Neuropathic Pain	1	2
Nonalcoholic fatty liver disease (NAFLD)	1	2
Organ Transplantation	1	2
Osteoporosis	2	2
Pain	1	2
Pancreatitis	1	2
Papillomavirus Infections	1	2
Polycystic Ovary Syndrome	1	2
Prenatal Chemical Exposures	1	2
Promyelocytic leukemia	2	2
Pulmonary Hypertension	1	2
Radiation Induced Illness	1	2
Respiratory Syncytial Virus Infections	1	2
Respiratory Tract Infections	1	2
Salivary Gland Adenoid Cystic Carcinoma.	2	2
Salivary Gland Diseases	2	2
Schwannoma: Vestibular	1	2
Seizures	1	2
Serotonin Disorders	1	2
Sickle Cell Anemia	1	2
Staphylococcal Infections	1	2
Stroke: Recovery	1	2
Testicular Injury: Cadmium-Induced	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Ulcerative Colitis	1	2
Ultraviolet Radiation Induced Damage	2	2
Acne	1	1
Allergies	1	1
Androgen-Induced Diseases	1	1
Aortic Plaques	1	1
Arsenic Poisoning	1	1
Bone Destructive Diseases: Over-Active Osteoclasts	1	1
Brain Cancer Stem Cells	1	1
Brain Injury: Hippocampal Damage	1	1
Breast Cancer Stem Cells	1	1
Breast Cancer: HER-2 Overexpressed	1	1
Burkitt Lymphoma	1	1
Candida Albicans	1	1
Candida Infection	1	1
Candidiasis	1	1
Cardiac Hypertrophy	1	1
Cholesterol: LDL/HDL ratio	1	1
Chronic Lymphocytic Leukemia	1	1
Colon Cancer Stem Cells	1	1
Colon Cancer: Prevention	1	1
Colorectal Tumors	1	1
Dopamine Deficiency	1	1
Drug-Induced Toxicity	1	1
Dystrophic retinal detachment (DRD)	1	1
Encephalomyelitis	1	1
Endometrial Cancer	1	1
Excitotoxicity	1	1
Fibrosis	1	1
Gastrointestinal Diseases	1	1
Gram-Negative Bacterial Infections	1	1
HIV Infections	1	1
Hepatitis C	1	1
Heterocyclic Aromatic Amine Induced Toxicity	1	1
Human Papillomavirus (HPV)	1	1
IgE-Mediated Hypersensitivity	1	1
Keloid	1	1
Kidney Damage	1	1
Leukemia: Acute myelogenous leukemia (AML)	1	1
Leukemia: Acute promyelocytic leukemia	1	1
Liver Cancer Stem Cells	1	1
Liver Failure: Acute	1	1
Lymphoma	1	1
Macular Degeneration	1	1
Malignant Melanoma	1	1
Medulloblastoma	1	1
Melanism	1	1
Microcystis aeruginosa	1	1
Mitochondrial Diseases	1	1
Muscle Atrophy	1	1
Neurological Conditions	1	1
Oral Cancer: Prevention	1	1
Osteoarthritis	1	1
Osteoporosis: Over-active Osteoclasts	1	1
Pancreatic Cancer Stem Cell	1	1
Pesticide Toxicity	1	1
Prediabetes	1	1
Restenosis	1	1
Retinal Diseases	1	1
Schizophrenic Disorders	1	1
Squamous cell carcinoma	1	1
Striatonigral Degeneration: Autosomal Dominant	1	1
Sunburn	1	1
Tin Poisoning	1	1

Name	AC	CK
Chemopreventive	96	318
Anticarcinogenic Agents	115	315
Antioxidants	108	254
Apoptotic	140	229
Antiproliferative	107	195
Anti-Inflammatory Agents	76	178
Nrf2 activation	73	142
Neuroprotective Agents	45	96
Cell cycle arrest	47	63
Interleukin-6 Downregulation	25	49
Tumor Necrosis Factor (TNF) Alpha Inhibitor	27	46
Phase II Detoxification Enzyme Inducer	17	44
Antioxidant Effects	14	43
Chemotherapeutic	26	43
NF-kappaB Inhibitor	30	42
Hepatoprotective	18	38
Anti-metastatic	22	33
Antineoplastic Agents	22	32
Cardioprotective	16	31
Chemosensitizer	23	30
Cyclooxygenase 2 Inhibitors	18	29
Interleukin-1 beta downregulation	17	29
Histone deacetylase inhibitor	16	26
MicroRNA modulator	20	25
Cytoprotective	6	23
Glutathione Upregulation	4	22
NF-E2-Related Factor-2 (Nrf2) Modulator	11	20
Anti-Apoptotic	10	19
Antioxidant	4	18
Enzyme Inhibitors	8	17
Chemoprotective Agents	9	15
Anti-Angiogenic	7	14
Heme oxygenase-1 up-regulation	10	14
Immunomodulatory	9	14
Superoxide Dismutase Up-regulation	5	13
Tumor Suppressor Protein p53 Upregulation	8	13
Anti-Allergic Agents	2	12
Detoxifier	3	12
Genoprotective	2	11
Matrix metalloproteinase-2 (MMP-2) inhibitor	6	11
Alpha-glucosidase inhibitor	1	10
Anti-atherogenic	1	10
Enzyme Inhibitors: Pancreatic Lipase	1	10
Insulin Down-Regulation	1	10
NADPH Oxidase Inhibitors	1	10
Insulin Sensitizers	3	9
Autophagy Up-regulation	4	8
Glucose Uptake Optimization	3	8
Matrix metalloproteinase-9 (MMP-9) inhibitor	6	8
Renoprotective	5	8
Angiogenesis Inhibitors	4	7
Anti-Tumor	2	7
Bcl-2 protein down-regulation	6	7
Gastrointestinal Agents	4	7
Anti Inflammatory	4	6
Anti-Fibrotic	5	6
Anti-Proliferative	2	6
Hypoglycemic Agents	4	6
Hypolipidemic	3	6
Immunomodulatory: Th17 downregulation	3	6
Wnt/β-catenin pathway down-regulation	2	6
Anti-Bacterial Agents	4	5
Anti-cancer	1	5
Antiviral Agents	4	5
HER-2 oncoprotein down-regulation	1	5
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	4	5
Hypoxia-inducible factor-1 (HIF-1) inhibitor	1	5
Immune Enhancing Properties	1	5
Prostaglandin E Synthase-1 (PGES-1) Down-Regulation	1	5
Regenerative	1	5
Telomerase Inhibitor	5	5
Antidepressive Agents	2	4
Antifungal Agents	3	4
Antinoceceptive	2	4
Catalase Up-Regulation	2	4
Interleukin-10 downregulation	2	4
Interleukin-18 down-regulation	2	4
Malondialdehyde Down-regulation	2	4
Nitric Oxide Inhibitor	2	4
Proteasome Inhibitors	3	4
Vascular Endothelial Growth Factor Inhibitors	2	4
Wnt/β-catenin signaling pathway modulation	4	4
Anti-Glycation Agents	2	3
Anti-Ulcer Agents	2	3
Interferon Gamma Reducer	2	3
Interleukin-10 upregulation	2	3
P21 Activation	2	3
Radioprotective	2	3
Anti-Anxiety Agents	1	2
Anti-Estrogenic	1	2
Anticholesteremic Agents	1	2
Anticonvulsants	1	2
Antimicrobial	1	2
Autophagy Inhibitors	1	2
Brain-derived neurotrophic factor modulator	1	2
Cytotoxic	2	2
Epidermal growth factor receptor (EGFR) inhibitor	1	2
Estrogen Receptor Modulators	2	2
Fertility Agents: Male	1	2
Gastroprotective	1	2
Heat Shock Protein Inducer	1	2
Hypotensive	1	2
Interleukin-17 downregulation	1	2
Interleukin-2 upregulation	1	2
Interleukin-23 Downregulation	1	2
Leptin Down-Regulation	1	2
Lipolytic	1	2
Malonaldehyde (MDA) Down-Regulation	1	2
Metallothionein Up-regulation	1	2
Neurogenesis	1	2
PI3K-AKT inhibitor	1	2
Pancreato Protective Agents	1	2
Peroxisome Proliferators	1	2
Phase I Detoxification Enzyme Inducer	1	2
Platelet aggregation inhibitor: collagen-induced aggregation	1	2
Prostaglandin PGE2 downregulation	1	2
Serotonergic	1	2
Antimitotic Agents	1	1
Beta-Defensin-2 Up-Regulation	1	1
Caspase-3 Activation	1	1
Cell Differentiation Inducer	1	1
DNA Repair Up-regulation	1	1
Interleukin-4 upregulation	1	1
Interleukin-8 downregulation	1	1
Multidrug Resistance Gene Modulators	1	1
Osteoprotective	1	1
Postaglandin PGE2 downregulation	1	1
Quinone Reductase-Inducer	1	1
Radiopharmaceuticals	1	1
Radiosensitizer	1	1
Survivin Down-Regulation	1	1
Vascular Cell Adhesion Molecule-1 Inhibitor	1	1
Vascular Endothelial Growth Factor Regulator	1	1
anti-inflammatory	1	1

[+]

Sulforaphane ameliorates lipid profile.Apr 07, 2021

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Pubmed Data : Prim Care Diabetes. 2016 Jan 6. Epub 2016 Jan 6. PMID: 26778708

Article Published Date : Jan 05, 2016

Study Type : Meta Analysis

Additional Links

Substances : Cruciferous Vegetables

Diseases : Diabetes Mellitus: Type 2: Prevention

Additional Keywords : Risk Reduction

[+]

Higher intake of fruits, vegetables or their fiber reduces the risk of type 2 diabetesDec 31, 2015

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Pubmed Data : J Diabetes Investig. 2016 Jan ;7(1):56-69. Epub 2015 Jun 22. PMID: 26816602

Article Published Date : Dec 31, 2015

Study Type : Meta Analysis

Additional Links

Substances : Berries: All, Cruciferous Vegetables, Fiber, Fruit: All, Green Leafy Vegetables

Diseases : Diabetes Mellitus: Type 2: Prevention

Additional Keywords : Risk Reduction

[+]

Sulforaphane and EGCG restore estrogen receptor expression by modulating epigenetic events in the breast cancer cell line MDA-MB-231.Oct 17, 2017

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Pubmed Data : Carcinogenesis. 2012 Jan ;33(1):101-7. Epub 2011 Nov 1. PMID: 22045030

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Pubmed Data : BMC Cancer. 2010 ;10:162. Epub 2010 Apr 27. PMID: 20423504

Article Published Date : Dec 31, 2009

Study Type : Human Study

Additional Links

Substances : Cruciferous Vegetables, Isothiocyanates

Diseases : Lung Cancer, Lung Cancer: Prevention, Smoking

Pharmacological Actions : Anticarcinogenic Agents

Additional Keywords : Risk Reduction

[+]

Consumption of broccoli sprouts modulated the excretion of biomarkers linked to inflammation and vascular reactions.Apr 14, 2015

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Pubmed Data : Food Chem. 2015 Apr 15 ;173:1187-94. Epub 2014 Nov 7. PMID: 25466142

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Pubmed Data : Nutrients. 2017 Mar 17 ;9(3). Epub 2017 Mar 17. PMID: 28304346

Article Published Date : Mar 16, 2017

Study Type : Human Study

Additional Links

Substances : Cruciferous Vegetables, Fiber, Fruit: All

Diseases : Cardiovascular Disease: Prevention, Cardiovascular Diseases

Pharmacological Actions : Cardioprotective

[+]

Cruciferous vegetable consumption was strongly associated with reduced risk of prostate cancer progression.Jun 30, 2012

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Pubmed Data : Int J Cancer. 2012 Jul 1 ;131(1):201-10. Epub 2011 Aug 30. PMID: 21823116

Article Published Date : Jun 30, 2012

Study Type : Human Study

Additional Links

Substances : Broccoli, Cruciferous Vegetables

Diseases : Prostate Cancer

Pharmacological Actions : Chemopreventive

Additional Keywords : Disease Progression, Risk Reduction

[+]

Cruciferous vegetable intake could influence breast cancer risk.Jul 31, 2017

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Pubmed Data : Br J Nutr. 2015 Apr ;113 Suppl 2:S102-10. PMID: 26148912

Article Published Date : Mar 31, 2015

Study Type : Human Study

Additional Links

Substances : Apples, Cruciferous Vegetables, Dietary Modification: Mediterranean Diet. , Fruit: All, Tomato, Vegetables: All

Diseases : Cancers: All

Additional Keywords : Risk Reduction

[+]

DIM improves the estrogen profile in postmenopausal women with a history of early-stage breast cancer. Jan 01, 2004

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Pubmed Data : Nutr Cancer. 2004;50(2):161-7. PMID: 15623462

Article Published Date : Jan 01, 2004

Study Type : Human Study

Additional Links

Substances : DIM (3,3'-diindolylmethane)

Diseases : Estrogen Dysregulation: 2/4/16 hydroxyestrone ratios

[+]

Effect of a sulforaphane supplement on muscle soreness and damage induced by eccentric exercise.Jan 11, 2021

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Pubmed Data : J Am Heart Assoc. 2018 Apr 4 ;7(8). Epub 2018 Apr 4. PMID: 29618474

[+]

Oral sulforaphane safely and effectively induces mucosal Phase II enzyme expression in the upper airway of human subjects. Mar 01, 2009

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Pubmed Data : Clin Immunol. 2009 Mar;130(3):244-51. Epub 2008 Nov 22. PMID: 19028145

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Pubmed Data : Front Nutr. 2021 ;8:778031. Epub 2021 Nov 24. PMID: 34901122

Pubmed Data : Am J Clin Nutr. 2019 Jul 3. Epub 2019 Jul 3. PMID: 31268126

Article Published Date : Jul 03, 2019

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Pubmed Data : Phytother Res. 2003 Jan;17(1):66-9. PMID: 20810543

Article Published Date : Jan 01, 2003

Study Type : Human Study

Additional Links

Substances : Sulforaphane

Diseases : Bladder Cancer, Bladder Degeneration, DNA damage

Pharmacological Actions : Chemopreventive, Genoprotective

[+]

Sulforaphane treatment resulted in a significant reduction in specific airway resistance and also increased small airway luminal area.Dec 31, 2014

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Pubmed Data : Clin Psychopharmacol Neurosci. 2015 Apr 30 ;13(1):62-7. PMID: 25912539

Article Published Date : Apr 29, 2015

Study Type : Human Study

Additional Links

Substances : Broccoli Sprouts, Sulforaphane

Diseases : Schizophrenia

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Plant Extracts, Significant Treatment Outcome

[+]

Supplementation with sulforaphane rich broccoli sprout extract could improve liver function through reduction of oxidative stress.Nov 20, 2015

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Pubmed Data : World J Gastroenterol. 2015 Nov 21 ;21(43):12457-67. PMID: 26604653

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Pubmed Data : Nutr Cancer. 2015 Sep 23:1-13. Epub 2015 Sep 23. PMID: 26399169

Article Published Date : Sep 22, 2015

Study Type : Human In Vitro

Additional Links

Substances : Cabbage

Diseases : Breast Cancer, Breast Cancer: Triple Negative

Pharmacological Actions : Chemopreventive, NF-E2-Related Factor-2 (Nrf2) Modulator

Additional Keywords : Vegetable Juice

[+]

Combination of epigallocatechin gallate and sulforaphane dounteracts In Vitro oxidative stress and delays stemness loss of amniotic fluid stem cells.Jan 01, 2018

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Pubmed Data : FEBS Open Bio. 2018 Dec ;8(12):2022-2034. Epub 2018 Nov 14. PMID: 30524952

Article Published Date : Dec 01, 2018

Study Type : Human In Vitro

Additional Links

Substances : Sulforaphane

Diseases : Breast Cancer: Estrogen

Additional Keywords : Estrogen Positive Breast Cancer, Folate, Methylation

[+]

Sulforaphane prevents hepatic insulin resistance through a ceramide-dependent mechanism.May 27, 2019

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Pubmed Data : Nutrients. 2019 May 27 ;11(5). Epub 2019 May 27. PMID: 31137828

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Pubmed Data : Curr Pharm Des. 2012 Aug 23. Epub 2012 Aug 23. PMID: 22950492

Article Published Date : Aug 22, 2012

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Aspirin-Induced Toxicity , NSAID-induced toxicity

[+]

3,3'-Diindolylmethane inhibits angiogenesis and the growth of transplantable human breast carcinoma in athymic mice.Apr 01, 2005

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Pubmed Data : Carcinogenesis. 2005 Apr;26(4):771-8. Epub 2005 Jan 20. PMID: 15661811

Article Published Date : Apr 01, 2005

Study Type : Animal Study

Additional Links

Substances : Cruciferous Vegetables

Diseases : Breast Cancer, Breast Cancer: Metastatic

Pharmacological Actions : Anti-Angiogenic, Anticarcinogenic Agents

[+]

A phenolic rich extract of wild cabbage has the potential to form a multi-component drug to target diabetes and its related complications.Dec 31, 2014

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Pubmed Data : Springerplus. 2015 ;4:212. Epub 2015 May 3. PMID: 26020019

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Cabbage

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Hypoglycemic Agents, Hypolipidemic, Superoxide Dismutase Up-regulation

Additional Keywords : Plant Extracts

[+]

A variety of vegetables reduce the absorption and enhance excretion of dioxin and furan toxins. May 01, 1999

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Pubmed Data : Br J Pharmacol. 2018 08 ;175(16):3333-3346. Epub 2018 Jul 3. PMID: 29797311

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Pubmed Data : Carcinogenesis. 2010 Feb ;31(2):239-45. Epub 2009 Jul 22. PMID: 19625346

Article Published Date : Jan 31, 2010

Study Type : Animal Study

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Substances : Indole-3-Carbinol, Myo-inositol

Diseases : Lung Cancer

Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Cyclooxygenase 2 Inhibitors

Problem Substances : Vinyl Carbamate

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Brassica rapa (Mustard Greens) have a protective effect on cisplatin-induced nephrotoxicity in cells and rats. Dec 01, 2006

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Pubmed Data : Biol Pharm Bull. 2006 Dec;29(12):2436-41. PMID: 17142978

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Pubmed Data : J Agric Food Chem. 2018 Jun 6 ;66(22):5574-5580. Epub 2018 May 23. PMID: 29730925

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Pubmed Data : Carcinogenesis. 1990 Jul;11(7):1159-63. PMID: 2372873

Article Published Date : Jul 01, 1990

Study Type : Animal Study

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Substances : Cabbage, Red Cabbage

Diseases : Breast Cancer: Prevention

Pharmacological Actions : Chemopreventive

[+]

Characterization of juice fermented with Lactobacillus plantarum EM and its cholesterol-lowering effects on rats fed a high-fat and high-cholesterol diet.Oct 31, 2019

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Pubmed Data : Eur J Nutr. 2020 Jul 10. Epub 2020 Jul 10. PMID: 32651764

Article Published Date : Jul 09, 2020

Study Type : Animal Study, In Vitro Study

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Substances : Broccoli, Sulforaphane

Diseases : Escherichia coli Infections

Pharmacological Actions : Antimicrobial

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Continuous exposure of pancreatic cancer cells to dietary bioactive agents does not induce drug resistance unlike chemotherapy.Dec 31, 2015

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Pubmed Data : Cell Death Dis. 2016 ;7(6):e2246. Epub 2016 Jun 2. PMID: 27253410

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Pubmed Data : Nutrients. 2020 Oct 15 ;12(10). Epub 2020 Oct 15. PMID: 33076301

Article Published Date : Oct 14, 2020

Study Type : Animal Study

Additional Links

Substances : Indole-3-Carbinol

Diseases : Citrobacter Infection

Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

dietary intake of SFN-rich broccoli sprouts during the juvenile and adolescence may prevent the onset of psychosis at adulthood. Dec 31, 2014

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Pubmed Data : PLoS One. 2015 ;10(6):e0127244. Epub 2015 Jun 24. PMID: 26107664

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Pubmed Data : J Nutr. 2009 Oct 28. PMID: 19864400

Article Published Date : Oct 28, 2009

Study Type : Animal Study

Additional Links

Substances : DIM (3,3'-diindolylmethane)

Diseases : Breast Cancer, Breast Cancer: Lung Metastasis

Pharmacological Actions : Anti-metastatic

[+]

Enhanced inhibition of lung adenocarcinoma by combinatorial treatment with indole-3-carbinol and silibinin.Mar 31, 2011

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Pubmed Data : Carcinogenesis. 2011 Apr ;32(4):561-7. Epub 2011 Jan 27. PMID: 21273642

Article Published Date : Mar 31, 2011

Study Type : Animal Study

Additional Links

Substances : Indole-3-Carbinol, Silibinin

Diseases : Lung Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive

Additional Keywords : Natural Substance Synergy

[+]

Glucoraphanin supplementation attenuated weight gain, decreased hepatic steatosis, and improved glucose tolerance and insulin sensitivity.Feb 15, 2017

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Pubmed Data : Diabetes. 2017 Feb 16. Epub 2017 Feb 16. PMID: 28209760

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Pubmed Data : Cancer Res. 1996 Feb 1;56(3):574-81. PMID: 8564974

Article Published Date : Feb 01, 1996

Study Type : Animal Study

Additional Links

Substances : Indole-3-Carbinol

Diseases : Cancers: Multi-Drug Resistant, Melanoma

[+]

Indole-3 carbinol, a compound found in cabbage, may prevent and treat breast cancer bone metastasis. Nov 01, 2006

Pubmed Data : BMC Biol. 2014 Sep 12 ;12:72. Epub 2014 Sep 12. PMID: 25209720

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Pubmed Data : Ann Surg. 2016 Jun 8. Epub 2016 Jun 8. PMID: 27280500

Article Published Date : Jun 07, 2016

Study Type : Animal Study

Additional Links

Substances : Indole-3-Carbinol

Diseases : Clostridium Infections

[+]

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Pubmed Data : Toxicol Appl Pharmacol. 2022 01 15 ;435:115853. Epub 2021 Dec 30. PMID: 34973289

Article Published Date : Jan 14, 2022

Study Type : Animal Study

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Substances : Indole-3-Carbinol

Diseases : Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Obesity may increase susceptibility to chronic pain often due to poor diet.Dec 31, 2017

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Pubmed Data : Eur J Pain. 2018 08 ;22(7):1203-1213. Epub 2018 Mar 2. PMID: 29436058

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Curcumin, EGCG (Epigallocatechin gallate), Ginseng, Resveratrol, Sulforaphane

Diseases : Chronic Pain, Inflammation, Obesity

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Inflammatory Diet, Risk Factors

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Oncogenic c-Myc is a target of sulforaphane to prevent and eliminate the onset of human prostate cancer.Mar 14, 2016

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Pubmed Data : J Cell Biochem. 2016 Mar 15. Epub 2016 Mar 15. PMID: 26990292

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Pubmed Data : J Surg Res. 2016 Jun 15 ;203(2):348-59. Epub 2016 Mar 24. PMID: 27363643

Article Published Date : Jun 14, 2016

Study Type : Animal Study

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Substances : Sulforaphane, Thymoquinone

Diseases : Gastric Ulcer

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Anti-Ulcer Agents, Antioxidants, Gastroprotective

[+]

Profile of insulin resistance in adipose tissue of diet induced obese mice in response to anti-obesity treatment.Apr 30, 2022

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Pubmed Data : FASEB J. 2022 May ;36 Suppl 1. PMID: 35559539

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Pubmed Data : Saudi J Biol Sci. 2020 Nov ;27(11):3145-3149. Epub 2020 Jul 14. PMID: 33100876

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Pubmed Data : Front Pharmacol. 2022 ;13:811257. Epub 2022 Mar 1. PMID: 35300301

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Retinitis Pigmentosa

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

[+]

Sulforaphane alleviated vascular remodeling in hypoxic pulmonary hypertension.Dec 31, 2022

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Pubmed Data : J Nutr Biochem. 2023 Jan ;111:109182. Epub 2022 Oct 9. PMID: 36220525

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Pubmed Data : J Neurosurg. 2017 Jan 6:1-12. Epub 2017 Jan 6. PMID: 28059653

Article Published Date : Jan 05, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Sulforaphane

Diseases : Glioblastoma

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Antiproliferative, Apoptotic, Cancer Stem Cells, glioblastoma (GBM), Sulforaphane

[+]

Sulforaphane alter the microbiota and mitigate colitis severity on mice ulcerative colitis induced by DSS.Jul 02, 2020

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Pubmed Data : Curr Pharm Des. 2017 Feb 6. Epub 2017 Feb 6. PMID: 28176666

Article Published Date : Feb 05, 2017

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Aspirin-Induced Toxicity , Drug-Induced Toxicity: Indomethacin, Helicobacter Pylori Infection, NSAID-induced toxicity

Pharmacological Actions : Antioxidants

Problem Substances : Aspirin , Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

[+]

Sulforaphane could ameliorate the progression of hyperuricemia.Nov 09, 2022

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Pubmed Data : J Adv Res. 2022 Nov 10. Epub 2022 Nov 10. PMID: 36371056

Article Published Date : Nov 09, 2022

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Hyperuricemia

Pharmacological Actions : Gastrointestinal Agents

[+]

Sulforaphane could inhibit inflammation in human umbilical vein ECs exposed to advanced glycation end products.Apr 20, 2016

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Pubmed Data : Nutr Metab Cardiovasc Dis. 2016 Apr 21. Epub 2016 Apr 21. PMID: 27212619

Article Published Date : Apr 20, 2016

Study Type : Animal Study, In Vitro Study

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Substances :

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Sulforaphane ameliorates lipid profile.Apr 07, 2021

Combined fruit and vegetable consumption was associated with decreased non-Hodgkin lymphoma risk.Jan 31, 2018

Consumption of cruciferous vegetables may reduce the risk of ovarian cancer.Dec 31, 2014

Cruciferous vegetable intake might be inversely associated with the incidence of pancreatic cancer. Dec 31, 2014