Curcumin

Name	AC	CK
Oxidative Stress	315	696
Inflammation	191	582
Diabetes Mellitus: Type 2	65	239
Breast Cancer	146	215
Obesity	55	197
Alzheimer's Disease	108	194
Depression	35	187
Nonalcoholic fatty liver disease (NAFLD)	31	179
Ulcerative Colitis	33	154
Colorectal Cancer	70	132
Osteoarthritis	32	129
Cancers: All	121	128
Osteoarthritis: Knee	19	124
Lipid Peroxidation	44	111
Prostate Cancer	76	111
Colon Cancer	82	110
Liver Cancer	72	109
Chemically-Induced Liver Damage	50	100
Coronavirus Infection	34	100
Lipopolysaccharide-Induced Toxicity	70	99
Lung Cancer	80	99
Cancers: Drug Resistant	77	95
Insulin Resistance	29	91
Rheumatoid Arthritis	19	89
Wound Healing	53	89
Inflammatory Bowel Diseases	39	88
C-Reactive Protein	10	87
Chronic Kidney Disease (CKD)	14	82
DNA damage	47	82
Polycystic Ovary Syndrome	13	81
Neurodegenerative Diseases	55	79
Pancreatic Cancer	39	78
Oral Cancer	31	77
Melanoma	43	73
Parkinson's Disease	49	72
Hypertension	17	69
Brain Inflammation	44	68
Endothelial Dysfunction	20	67
Colitis	30	66
Aging	30	64
Oral Submucous Fibrosis	8	64
Multiple Myeloma	18	62
Chemotherapy-Induced Toxicity: Cisplatin	33	59
Cancer Metastasis	44	58
Glioblastoma	31	58
Hyperlipidemia	20	58
Skin Cancer	22	58
Liver Fibrosis	35	57
Periodontitis	13	56
Alcohol Toxicity	23	55
Atherosclerosis	25	53
Head and Neck Cancer	24	53
Hyperglycemia	15	53
Oral Mucositis	6	52
Arthritis	19	49
Epilepsy	19	49
Spinal Cord Injuries	14	49
Gastric Cancer	36	48
Helicobacter Pylori Infection	16	48
Cardiovascular Diseases	23	46
Metabolic Syndrome X	9	46
Muscle Damage: Exercise-Induced	8	45
Psoriasis	19	45
Cervical Cancer	39	44
Depressive Disorder	5	44
Diabetic Nephropathy	17	44
Myocardial Infarction	14	43
Dysmenorrhea	6	42
Radiation Induced Illness	24	42
Tumors	22	42
Asthma	20	41
Premenstrual syndrome	5	41
Arsenic Poisoning	13	39
Diabetic Complications	23	39
Proteinuria	7	39
Anxiety	9	38
Brain Injury: Traumatic	11	38
Cognitive Decline/Dysfunction	17	38
Fatty Liver	12	38
Brain: Oxidative Stress	11	37
Cholestasis	7	37
HIV Infections	20	37
Ovarian Cancer	34	37
Periodontal Diseases	8	37
Pesticide Toxicity	21	37
Breast Cancer: Triple Negative	25	36
High Fat Diet	18	36
Metabolic Diseases	13	36
Cancers: Multi-Drug Resistant	34	34
Diabetes Mellitus: Type 1	19	34
Glioma	24	34
Bladder Cancer	27	33
Leukemia	31	33
Thalassemia	6	33
Advanced Glycation End products (AGE)	8	32
Alcoholic Liver Disease	9	32
Chemical Weapon Agent Injury: Sulfur Mustard	4	32
Chemotherapy-Induced Toxicity: Doxorubicin	14	32
Diabetic Retinopathy	11	32
Headache: Migraine	4	32
Leukoplakia	5	32
Muscle Damage	3	32
Benzo[a]pyrene-induced Toxicity	19	31
Irritable Bowel Syndrome	9	31
Multiple Sclerosis	16	31
Myocardial Ischemia	13	31
Spondylitis: Ankylosing	2	31
Diabetes: Cardiovascular Illness	12	30
Human Papillomavirus (HPV)	15	30
Liver Damage	17	30
Memory Disorders	15	30
Squamous cell carcinoma	23	30
Sepsis	13	29
Aflatoxicosis	15	28
Brain Ischemia	15	28
Liver Damage: Drug-Induced	12	28
Pulmonary Fibrosis	15	28
Testicular Injury: Chemical/Metal Induced	14	28
Aluminum Toxicity	15	27
Lung Injury: Acute	14	27
Malaria	20	27
Systemic Lupus Erythematosus	5	27
Carcinoma: Non-Small-Cell Lung	21	26
Chemotherapy and Radiation Toxicity	5	26
Uveitis	6	26
Chronic Pain	9	25
Dry Eye Syndromes	5	25
Endometriosis	14	25
High Cholesterol	9	25
Cholesterol: Oxidation	11	24
Diabetic Neuropathy	3	24
Familial Adenomatous Polyposis	4	24
Gingivitis	6	24
Infertility: Male	8	24
Kidney Damage	12	24
Postmenopausal Disorders	4	24
Stress	8	24
Aging: Brain	8	23
Cerebral Ischemia	13	23
Colitis: Ulcerative	2	23
Dental Plaque	5	23
Oral Lichen Planus	3	23
Staphylococcus aureus infection	15	23
Cadmium Poisoning	12	22
Candidiasis	3	22
Macular Degeneration	12	22
Overweight	3	22
Prostatic Hyperplasia	2	22
Stroke: Ischemic	9	22
Acetaminophen (Tylenol) Toxicity	13	21
Bisphenol Toxicity	10	21
Dyslipidemias	7	21
Ischemia	12	21
Liver Steatosis	7	21
Cholesterol: LDL/HDL ratio	2	20
Colon Polyps	6	20
Crohn's Disease	9	20
HDL: Low	2	20
Hypercholesterolemia	6	20
Liver Cirrhosis	7	20
Postoperative Recovery	2	20
Smoldering multiple myeloma (SMM)	2	20
Chemotherapy-Induced Toxicity: Bleomycin	10	19
Cystic Fibrosis	9	19
Diabetes: Oxidative Stress	11	19
Liver Damage: Aflatoxin-Induced	10	19
Osteoporosis	13	19
Promyelocytic leukemia	19	19
Thrombosis	7	19
Brain Cancer	8	18
Cataract	11	18
Lung Damage	9	18
Neuropathic Pain	10	18
Nicotine/Tobacco Toxicity	11	18
Prediabetes	4	18
Anxiety Disorders	5	17
Coronavirus Disease (Covid-19)	8	17
Dementia	5	17
Endotoxemia	9	17
Hypoxia	12	17
Leukemia: Chronic myelogenous leukemia (CML)	7	17
Neuroblastoma	13	17
Radiation Induced Illness: Mucositis	5	17
Seizures	8	17
Stroke: Attenuation/Recovery	10	17
Chemotherapy-Induced Toxicity: Cyclophosphamide	10	16
Coronary Artery Disease	4	16
Dysbiosis	5	16
Esophageal Cancer	13	16
Gastric Ulcer	9	16
Iron Overload	7	16
Lymphoma	13	16
Pancreatitis	9	16
Triglycerides: Elevated	4	16
Allergies	12	15
Brain: Microglial Activation	12	15
Cholesterol: High	4	15
Chronic Obstructive Pulmonary Disease	6	15
Gastrointestinal Inflammation	8	15
Muscle Atrophy	9	15
Amyotrophic lateral sclerosis (ALS)	5	14
Dejerine-Sottas Disease	3	14
Depression	3	14
Fatigue: Excercise-Induced	3	14
Glaucoma	5	14
Hearing Loss	3	14
Leukemia: Chronic Lymphocytic Leukemia (CLL)	5	14
Muscle Soreness: Exercise-Induced	3	14
Peripheral Neuropathies	3	14
Prostatitis: Chronic	3	14
Vitiligo	5	14
Acne	3	13
Adiponectin: Low Levels	3	13
Arthritis: Rheumatoid	4	13
Chemotherapy-Induced Toxicity: Tamoxifen	3	13
Diabetes: Cognitive Dysfunction	7	13
Drug Toxicity: Methotrexate	7	13
Eye Diseases	4	13
Fibrosis	3	13
Gastrointestinal polyps	3	13
Heart Failure	8	13
Hyperalgesia	6	13
Mitochondrial Dysfunction	9	13
Myocardial Fibrosis	7	13
Osteosarcoma	11	13
Plasma Cell Dyscrasias	2	13
Sarcopenia	3	13
Thyroid Diseases	3	13
Acute Myeloid Leukemia	8	12
Allergic Rhinitis	2	12
Altitude Sickness	2	12
Chemical Exposure	7	12
Chemotherapy-Induced Toxicity	8	12
Chemotherapy-Induced Toxicity: Gentamicin	6	12
Cirrhosis	2	12
Drug-Induced Toxicity	6	12
Escherichia coli Infections	10	12
Insulin: Low	2	12
Left Ventricular Dysfunction	2	12
Liver Disease	7	12
Maculopathy: Age-Related	2	12
Middle Cerebral Artery Occlusion (MCAO)	6	12
Pain	6	12
Precancerous Conditions	2	12
Prostate: PSA Doubling	3	12
Allergic Airway Diseases	6	11
Autoimmune Diseases	11	11
Brain Injury: Hippocampal Damage	7	11
Dermatitis	2	11
Diabetes	2	11
Diabetes Mellitus: Type 2: Prevention	2	11
High Fructose Diet	6	11
Immune Disorders: Low Immune Function	6	11
Kidney Damage: Chemically-Induced	6	11
Neurofibromatosis	2	11
Peptic Ulcer	2	11
Phthalate Toxicity	6	11
Prostate Cancer: Metastatic	2	11
Pruritus	2	11
Radiation	6	11
Schizophrenia	2	11
ALT: Elevated	1	10
Abdominal Obesity (Midsection Fat)	1	10
Biliary Dyskinesia	1	10
Brain Damage	6	10
Breast Cancer: Metastatic	8	10
Bronchial Asthma	1	10
C-Reactive Protein: Diabetes-Associated	1	10
Cardiac Hypertrophy	7	10
Chemical Weapon Agent Injury	1	10
Chemotherapy	7	10
Coronary Bypass Surgery	1	10
Dementia with Lewy bodies (DLB)	1	10
Dental Care	1	10
Depression: Postpartum	1	10
Diabetic Microangiopathy	1	10
Diarrhea	1	10
Dyspepsia	1	10
Epileptic Seizures	4	10
Fluoride Toxicity	5	10
Gallbladder Disease	1	10
Gammopathy: Monoclonal	1	10
Gram-Negative Bacterial Infections	5	10
Gulf War Syndrome	1	10
Halitosis	1	10
Hemodialysis	1	10
Hemoglobinopathies	1	10
Hot Flash	1	10
Influenza A	7	10
Insulin Disorders	1	10
Intestinal Polyps	5	10
Kidney Damage: Drug-Induced	5	10
Kidney Fibrosis	5	10
Lead Poisoning	6	10
Leukemia: Acute myelogenous leukemia (AML)	8	10
Leukemia: B-Cell	1	10
Lichen Planus	1	10
Lichen Sclerosus	1	10
Lupus Erythematosus: Cutaneous	1	10
Maculopathy	1	10
Mastitis	1	10
Monoclonal Gammopathies	1	10
Obesity: Abdominal	1	10
Orbital Pseudotumor	1	10
Organ Transplantation: Kidney	1	10
Plasma beta amyloid protein concentrations: elevated	1	10
Plasma catalase activities: elevated	1	10
Proctitis	1	10
Proctocolitis: Ulcerative	1	10
Pseudomonas aeruginosa	8	10
Quality of Life: Poor	1	10
Respiratory Infections: Infants & Children	1	10
Respiratory Tract Infections	1	10
Salivary amylase levels: elevated	1	10
Sciatic Nerve Crush Injury	5	10
Soluble cell adhesion molecules (sCAMs): elevated	1	10
Spinal Cord Inflammation	1	10
Stomatitis: Aphthous	1	10
Stroke	7	10
T-Cell Lymphoma: Cutaneous	1	10
Ulcer: Aphthous	1	10
Urinary Tract Infections	1	10
Vaginosis: Bacterial	1	10
Vertigo	1	10
Burns	5	9
Cachexia	5	9
Cholangiocarcinoma	5	9
Gastrointestinal Cancer	6	9
Heat Stroke	5	9
Hepatic Steatosis	5	9
Nasopharyngeal Cancer	8	9
Organ Transplantation	6	9
Parasitic Diseases	5	9
Testicular Diseases	5	9
Thyroid Cancer	9	9
Antibiotic Toxicity	4	8
Cardiomyopathy	5	8
Chemotherapy-Induced Kidney Damage	4	8
Copper Toxicity	5	8
Diabetes: Kidney Function	4	8
Endometrial Cancer	6	8
Herpes Simplex Virus Type 2	4	8
Leishmaniasis	8	8
Lymphoma: B-Cell	8	8
Memory Disorders: Drug-Induced	4	8
Sperm Quality: Low	4	8
Staphylococcus aureus: Methicillin-resistant (MRSA)	7	8
Acute lymphoblastic leukemia (ALL)	5	7
Cancer Stem Cells	7	7
Candida Infection	7	7
Chemotherapy-Induced Toxicity: 5-fluorouracil	4	7
Colon Cancer: Prevention	4	7
Colorectal Cancer: Prevention	4	7
Dengue	6	7
Drug-Induced Toxicity: Indomethacin	4	7
Huntington Disease	6	7
Hypersensitivity	4	7
Mesothelioma	5	7
Non-Small-Cell Lung Carcinoma	7	7
Subarachnoid hemorrhage	4	7
Amyloidosis	3	6
Amyotrophic Lateral Sclerosis	5	6
Aneurysm: Aortic	3	6
Arteriosclerosis	4	6
Autism Spectrum Disorders	4	6
Brain Edema	3	6
Cytomegalovirus Infections	4	6
Excitotoxicity	6	6
Flukes	3	6
Fungal Infection	5	6
Immune Dysregulation: TH1/TH2 imbalance	3	6
Influenza	4	6
Intestinal Cancer	3	6
Iron Poisoning	4	6
Leptin: Elevated Levels	4	6
Liver Diseases	5	6
Memory Loss	3	6
Mycobacterium abscessus	3	6
Peripheral Nerve Diseases	3	6
Smoking	4	6
Wound Healing: Delayed	3	6
Acute Myeloid Leukemia: Stem Cell	1	5
Acute T cell Leukemias	5	5
Bacterial Vaginosis	1	5
Bone Diseases	2	5
Brain Diseases	4	5
Cholera	1	5
Chronic Myeloid Leukemia	5	5
Degenerative Disk Disease	3	5
Diabetes Mellitus: Type 1: Prevention	3	5
Dioxin Toxicity	3	5
Epstein-Barr Virus Infections	4	5
Gallstones	3	5
Gastrointestinal Infections	1	5
Glomerulosclerosis	3	5
Hepatitis C	5	5
Homocysteine: Elevated	3	5
Intestinal Permeability	3	5
Intracerebral Hemorrhage	3	5
Klebsiella Infections	3	5
Leukemia: Monocytic	3	5
Liver Cancer: Prevention	3	5
Pituitary Tumours	4	5
Pneumonia	3	5
Radiation Associated Toxicity: Cobalt-60	1	5
Retinal Diseases	4	5
Retinoblastoma	5	5
Yeast Infection: Vaginal	1	5
Acinetobacter baumannii infection	4	4
Angiostrongylus Cantonensis Infection	2	4
Anti-Malarial Drug Toxicity	2	4
Aortic Stenosis	2	4
Blood Sugar Problems	2	4
Blood-Brain-Barrier Disorders	2	4
Breast Cancer Stem Cells	4	4
Burkitt Lymphoma	3	4
Cachexia: Cancer	2	4
Charcot-Marie-Tooth Disease	2	4
Chemotherapy Induced Myelotoxicity	2	4
Chemotherapy-Induced Toxicity: Adriamycin	2	4
Demyelinating Diseases	2	4
Diabetes: Liver Disease	2	4
Diabetic Neuropathies	2	4
Drug-Induced Toxicity: Cyclosporine	2	4
Drug-Induced Toxicity: Haloperidol	2	4
Drug-Induced Toxicity: Valproic Acid (Depakote)	2	4
Encephalitis: Japanese	3	4
Encephalopathies	2	4
Enterococcus Infections	4	4
Eosinophilic Meningitis	2	4
Fever	2	4
Fibrosis: Liver	2	4
Gastritis	2	4
Giardiasis	3	4
Hepatitis B	4	4
Hepatitis: Lectin-Induced (concanavalin)	2	4
Hepatoma	3	4
Herbicide Toxicity	2	4
Hydrogen Peroxide Induced Toxicity	4	4
Hypercapnia	2	4
Hyperthyroidism	2	4
Intestinal Ischemia	2	4
Learning disorders	2	4
Left Ventricular Hypertrophy	2	4
Leiomyoma	3	4
Leptin Resistance	2	4
Lung Inflammation	2	4
Lupus Erythematosus: Systemic	3	4
Morphine Tolerance/Dependence	2	4
Mucositis	3	4
Myelodysplastic Syndromes	2	4
Neuropathies	2	4
Oral Cancer: Prevention	3	4
Organ Transplantation: Heart	2	4
Organ Transplantation: Pancreatic Islet Cells	3	4
Ovarian Diseases	2	4
Pancreatic Cancer: Metastatic	1	4
Paraquat Toxicity	2	4
Peripheral Arterial Disease	2	4
Peripheral Nerve Damage	2	4
Polycystic Kidney Diseases	2	4
Post-Traumatic Stress Disorders (PTSD)	3	4
Prenatal Chemical Exposures	2	4
Prion Diseases	3	4
Respiratory Syncytial Virus Infections	3	4
Retinitis Pigmentosa	3	4
Rhabdomyosarcoma	3	4
Sciatica	2	4
Sickle Cell Anemia	2	4
Tendon Injury	2	4
Tobacco Toxicity	2	4
Tongue Cancer	3	4
Acrylamide-induced toxicity	2	3
Adult T-cell leukemia/lymphoma (ATL)	2	3
Air Pollution Linked Toxicity	2	3
Anaphylaxis	2	3
Animal Diseases: Infectious	1	3
Animal Diseases: Porcine Epidemic Diarrhea Virus (PEDV)	1	3
Bacterial Infections and Mycoses	2	3
Bladder Cancer: Prevention	2	3
Brain Hypoxia	2	3
Breast Cancer: Lung Metastasis	2	3
Candida Albicans	3	3
Cardiomegaly	2	3
Central Nervous System Diseases	3	3
Chemotherapy-Induced Toxicity: Mitomycin-C	2	3
Circulating Free Fatty Acids: Elevated	2	3
Corticosteroid-Induced Toxicity	3	3
Cortisol: High	2	3
Diabetes: Cataract	2	3
Diabetes: Glycation/A1C	2	3
Endothelial Damage	2	3
Fibrosarcoma	2	3
Fructose-Induced Toxicity	2	3
Gastroenteritis	2	3
Heavy Metal Toxicity	2	3
Hemangioendothelioma	1	3
Herpes Labialis	1	3
Human T-Cell Lymphotrophic Virus type 1 associated disease	2	3
Hypothyroidism	2	3

Name	AC	CK
Anti-Inflammatory Agents	667	1786
Antioxidants	659	1407
Apoptotic	573	723
Neuroprotective Agents	365	696
Antiproliferative	494	684
Tumor Necrosis Factor (TNF) Alpha Inhibitor	215	537
Hepatoprotective	186	487
NF-kappaB Inhibitor	313	469
Antineoplastic Agents	321	439
Interleukin-6 Downregulation	119	327
Hypoglycemic Agents	56	283
Chemopreventive	168	282
Hypolipidemic	57	260
Immunomodulatory	107	239
Antidepressive Agents	36	207
Renoprotective	82	205
Cardioprotective	85	184
Gastrointestinal Agents	53	176
Chemoprotective Agents	59	165
Anti-Apoptotic	101	163
Enzyme Inhibitors	102	163
Anti-metastatic	124	162
Analgesics	32	153
Cell cycle arrest	128	151
Chemosensitizer	132	150
Interleukin-1 beta downregulation	73	150
Anti-Bacterial Agents	71	144
Anticarcinogenic Agents	93	144
Chemotherapeutic	84	129
Cyclooxygenase 2 Inhibitors	82	127
Superoxide Dismutase Up-regulation	33	127
Antiviral Agents	95	124
Malondialdehyde Down-regulation	28	114
Radioprotective	39	94
Anti-Fibrotic	37	83
Nrf2 activation	46	78
MicroRNA modulator	50	75
Tumor Suppressor Protein p53 Upregulation	55	74
Insulin Sensitizers	11	65
Interleukin-10 upregulation	15	61
Matrix metalloproteinase-2 (MMP-2) inhibitor	40	57
Anti-Angiogenic	37	53
Anti-Anxiety Agents	9	47
Antimicrobial	19	47
Interleukin-8 downregulation	20	47
Matrix metalloproteinase-9 (MMP-9) inhibitor	33	46
Osteoprotective	16	41
Anticholesteremic Agents	9	40
Heme oxygenase-1 up-regulation	23	39
Gastroprotective	19	38
Genoprotective	19	38
Nitric Oxide Inhibitor	20	38
Antifungal Agents	16	36
Antihypertensive Agents	14	36
Radiosensitizer	27	34
Cytoprotective	19	32
Angiogenesis Inhibitors	25	31
Wnt/β-catenin signaling pathway modulation	21	31
Cholagogues and Choleretics	3	30
Prophylactic Agents	10	30
Anticonvulsants	14	28
Interleukin-4 downregulation	7	28
Vascular Endothelial Growth Factor A Inhibitor	20	28
Anti-Ulcer Agents	11	27
Prostaglandin PGE2 downregulation	14	26
Anti-Infective Agents	5	25
Interleukin-17 downregulation	5	25
Pancreato Protective Agents	10	25
Vascular Endothelial Growth Factor Inhibitors	14	24
SIRT1 Activator	9	23
Anti-Tumor	10	22
Bcl-2 protein down-regulation	19	22
Adiponectin upregulation	3	21
Heat Shock Protein Inducer	13	20
Matrix metalloproteinase-3 (MMP-3) inhibitor	7	19
Chondroprotective	7	18
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	7	18
Regenerative	10	18
Anti-Proliferative	15	17
Antimutagenic Agents	14	17
Antinoceceptive	9	17
Epidermal growth factor receptor (EGFR) inhibitor	15	17
Histone deacetylase inhibitor	15	17
Proteasome Inhibitors	12	17
Anti-Glycation Agents	3	16
Antimalarials	14	16
Autophagy Up-regulation	14	16
P21 Activation	7	16
Vasoprotective	5	16
Immunostimulatory	10	15
Anti-Allergic Agents	10	14
Transforming growth factor beta (TGF-β) inhibitor	9	14
Anti-atherogenic	3	13
Antiparasitic Agents	9	13
Immunomodulatory: Th17 downregulation	3	13
Neurogenesis	8	13
Catalase Up-Regulation	2	12
Iron Chelating Agents	2	12
Nitric Oxide Enhancer	2	12
Transforming growth factor beta (TGF-β) upregulation	2	12
Caspase-3 Activation	7	11
Dermatologic Agents	2	11
STAT3 Inhibitor	9	11
Beta-Defensin-2 Up-Regulation	1	10
Cytotoxic	10	10
Immunosuppressive Agents	7	10
Interleukin-10 downregulation	6	10
Interleukin-22 Downregulation	1	10
Malonaldehyde (MDA) Down-Regulation	1	10
Phosphorylase Kinase Inhibitors	1	10
VEGFR3 inhibition	1	10
anti-inflammatory	1	10
Oncogene Suppressor	6	9
Acetylcholinesterase Inhibitor	5	8
Angiotensin-Converting Enzyme Inhibitors	5	8
Bax/Bcl2 ratio: Increase	4	8
Cyclooxygenase Inhibitors	7	8
Fertility Agents: Male	4	8
Leishmanicidal	8	8
Lipoxygenase Inhibitors	8	8
Multidrug Resistance Gene Modulators	7	8
Wnt/β-catenin pathway down-regulation	7	8
Anti-Asthmatic Agents	4	7
Autophagy Inhibitors	5	7
Brain-derived neurotrophic factor modulator	4	7
Cardiovascular Agents	4	7
Cyclooxygenase 1 Inhibitor	7	7
Detoxifier	5	7
Protein Kinase Inhibitors	6	7
Anti-Cachexic Agents	3	6
Neuritogenic	4	6
Telomerase Inhibitor	6	6
Vasodilator Agents	3	6
Adiponectin Down-Regulation	1	5
Anti-Platelet	4	5
Anti-Retroviral Agents	1	5
Bax/Bcl2 Ratio: Decrease	3	5
Heme oxygenase-1 inducer	4	5
Interferon Gamma Reducer	3	5
Interleukin-18 down-regulation	3	5
Interleukin-4 upregulation	3	5
Platelet Aggregation Inhibitors	3	5
Spermicidal Activity	1	5
Anti-pyretic	2	4
Antispasmodic	2	4
Cell Differentiation Inducer	3	4
Glutathione Upregulation	2	4
Interleukin-2 Downregulation	2	4
Monoaminergic	2	4
Neurorestorative	2	4
Photosensitizing Agents	3	4
Vascular Cell Adhesion Molecule-1 Inhibitor	4	4
Vitamin D Receptor (VDR) Modulator	3	4
AMP-activated protein kinase modulation	2	3
Chelating Agents	2	3
Cyclin D1 Down-Regulation	3	3
Drug synergy	2	3
Estrogen Receptor Modulators	2	3
Excitatory Amino Acid Agonists	2	3
Interleukin-5 downregulation	2	3
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	3
Paraptosis	3	3
Postaglandin PGE2 downregulation	3	3
Proliferative	2	3
AKT-mammalian target of rapamycin (mTOR) pathway inhibitor	2	2
Adenosine deaminase inhibitor	1	2
Alpha-glucosidase inhibitor	2	2
Analgesics: Non-Narcotic	1	2
Analgesics: Opioid	1	2
Androgen Antagonists	1	2
Angiogenesis Inducing Agents	1	2
Angiogenesis Modulating Agents	1	2
Anti-Androgen	1	2
Anti-Inflammatory Agents: Non-Steroidal	1	2
Anti-thrombotic	1	2
Antigiardial agents	1	2
Antioxidant Effects	2	2
Anxiolytic	1	2
Calcium Channel Blockers	2	2
Cholinesterase Inhibitors	1	2
Fibroblast growth factor 21 upregulation	1	2
Gluconeogenesis Inhibitor	2	2
Glutathione S-transferase Inhibitor	2	2
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor	2	2
HIV Protease Inhibitors	2	2
Heat Shock Protein Down-Regulation	2	2
High-mobility group box-1 (HMGB1) inhibitor	1	2
Histamine H2 Antagonists	2	2
Hypoxia-inducible factor-1 (HIF-1) inhibitor	1	2
Insulin Receptor Modulator	1	2
Insulin-Like Growth Factor Inhibition/Downregulation	2	2
Insulin-releasing	1	2
Interleukin-1 alpha downregulation	1	2
Interleukin-21 downregulation	1	2
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	1	2
Matrix Metalloproteinases Inhibitors	1	2
Metal Chelation: Copper	1	2
Muscarinic Agonists	1	2
Myorelaxant	1	2
NF-E2-Related Factor-2 (Nrf2) Modulator	2	2
Neuromodulatory	1	2
Phase II Detoxification Enzyme Inducer	1	2
Photoprotective	1	2
Prostaglandin Antagonists	1	2
Proton Pump Inhibitor	1	2
Quorum Sensing Inhibition	2	2
Redox Modulator	1	2
Remyelination	1	2
Schistosomicides	1	2
Serotonin Agonists	1	2
Survivin Down-Regulation	2	2
Thromboxane (TXB) Inhibitors	1	2
Vascular Endothelial Growth Factor C Inhibitor	1	2
Vascular Endothelial Growth Factor Regulator	1	2
Vascular smooth muscle cell (VSMC) inhibitor	2	2
Xanthine oxidase inhibitor	2	2
Akt-SREBP-1 activater	1	1
Aldose reductase inhibitor	1	1
Alpha-amylase inhibitor	1	1
Anti Inflammatory	1	1
Anti-Adipogenic	1	1
Anti-HIV Agents	1	1
Anti-Infective Agents: Urinary	1	1
Anti-fungal effects	1	1
Antibiotics: Antifungal	1	1
Antidepressive Agents: Second-Generation	1	1
Antilipolytic	1	1
Antimycobacterial	1	1
Appetite Suppresant	1	1
Calcium/calmodulin dependent protein kinase II inhibitor	1	1
Cannabinoid Receptor Antagonist/Inverse Agonist	1	1
Carbonyl Reductase 1Inhibitor	1	1
Caspase-9 Activation	1	1
Enzyme Activators	1	1
Enzyme Inhibitors: Pancreatic Lipase	1	1
Eryptotic	1	1
Expectorants	1	1
Fatty Acid Synthesis Inhibitors	1	1
Glucose transporter-1 (GLUT1) expression down-regulation	1	1
Glucose transporter-2 (GLUT2) expression down-regulation	1	1
Glucose transporter-5 (GLUT5) expression down-regulation	1	1
Glyoxalase 1 inhibitor	1	1
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Inhibitor	1	1
Hypomethylating	1	1
Hypotensive	1	1
Inhibitor of Nuclear Factor Kappa-B Kinase (IKK)	1	1
Insect Repellents	1	1
Interferon-gamma (IFN-gamma) inducer	1	1
Interleukin-12 downregulation	1	1
Interleukin-6 upregulation	1	1
Intracellular adhesion molecule-1 (ICAM-1)	1	1
Leptin Down-Regulation	1	1
Leukotriene B4 downregulation	1	1
Leukotriene C4 Downregulation	1	1
Maspin (Protease Inhibitor) Up-Regulation	1	1
Mast Cell Activation Inhibitor	1	1
Matrix Metalloproteinase-7 (MMP-7) Inhibitor	1	1
Matrix metalloproteinase-14 (MMP-14) inhibitor	1	1
Matrix metalloproteinase-16 (MMP-16) inhibitor	1	1
Matrix metalloproteinase-17 (MMP-17) inhibitor	1	1
Neuroplasticity enhancement	1	1
Nonpeptidyl Inhibitors	1	1
Osteogenic	1	1
P-glycoprotein Inhibitors	1	1
P16 Activation	1	1
PI3K-AKT inhibitor	1	1
PRL-3 Down-Regulation	1	1
Palmitoylation Inhibitors	1	1
Phosphodiesterase Inhibitors	1	1
Phospholipase D Inhibitors	1	1
Protease Inhibitors	1	1
Reactive Oxygen Species (ROS) attenuation	1	1
Receptor activator of NF-κB (RANK) gene expression	1	1
S-phase kinase associated protein 2 inhibition	1	1
STAT3-NFκB Signaling: downregulation	1	1
Secretagogue	1	1
Transient Receptor Potential Melastatin 2 Inhibition	1	1
Trypanocidal Agents	1	1
Tumor Necrosis Factor (TNF) Alpha Enhancer	1	1
apoptosis	1	1

[+]

Click here to read the entire abstract

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Pubmed Data : Health Sci Rep. 2025 Mar ;8(3):e70525. Epub 2025 Mar 2. PMID: 40041784

Article Published Date : Feb 28, 2025

Study Type : Meta Analysis, Review

Additional Links

Substances : Curcumin

Diseases : Polycystic Ovary Syndrome

Pharmacological Actions : Hypoglycemic Agents, Insulin Sensitizers

[+]

Curcumin supplementation significantly reduces anthropometric indices.Apr 30, 2023

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Pubmed Data : Biomedicine (Taipei). 2019 Dec ;9(4):23. Epub 2019 Nov 14. PMID: 31724938

Article Published Date : Nov 30, 2019

Study Type : Meta Analysis

Additional Links

Substances : Curcumin

Diseases : Brain: Oxidative Stress

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation

[+]

A review of the beneficial effects of antioxidants on Helicobacter pylori eradication.Nov 30, 2018

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Pubmed Data : Helicobacter. 2018 Dec ;23(6):e12535. Epub 2018 Sep 6. PMID: 30191635

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Pubmed Data : Pharmacol Res. 2017 Sep 16. Epub 2017 Sep 16. PMID: 28928074

Article Published Date : Sep 15, 2017

Study Type : Meta Analysis, Review

Additional Links

Substances : Curcumin, Curcuminoids

Diseases : Hyperglycemia

Pharmacological Actions : Hypoglycemic Agents

[+]

Curcumin supplementation has favorable effect on metabolic markers and anthropometric parameters in patients with NAFLD.Dec 31, 2019

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Pubmed Data : Iran J Kidney Dis. 2022 May ;16(3):153-161. PMID: 35714209

Article Published Date : Apr 30, 2022

Study Type : Meta Analysis

Additional Links

Substances : Curcumin

Diseases : Chronic Kidney Disease (CKD), Proteinuria

Pharmacological Actions : Renoprotective

[+]

Impact of exercise intervention with or without curcumin supplementation on body fat composition, glucose, and lipid metabolism in obese adults.Feb 28, 2025

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Pubmed Data : Lipids. 2025 Mar ;60(2):65-75. Epub 2024 Nov 7. PMID: 39508270

Article Published Date : Feb 28, 2025

Study Type : Meta Analysis

Additional Links

Substances : Curcumin

Diseases : Obesity

Therapeutic Actions : Exercise

Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic

Additional Keywords : Anti-Obesity Agents

[+]

Influence of phytosomal curcumin on anthropometric indices for nonalcoholic fatty liver disease.Dec 26, 2024

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Pubmed Data : Medicine (Baltimore). 2024 Dec 27 ;103(52):e40538. PMID: 39969338

Article Published Date : Dec 26, 2024

Study Type : Meta Analysis

Additional Links

Substances : Curcumin

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

Meta-analysis of randomized controlled trials of 4 weeks or longer suggest that curcumin may afford some protection against oxidative stress.Jan 11, 2018

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Pubmed Data : Nutr Res. 2018 12 ;60:1-12. Epub 2018 Sep 4. PMID: 30527253

Article Published Date : Jan 11, 2018

Study Type : Meta Analysis

Additional Links

Substances : Curcumin

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation

[+]

Click here to read the entire abstract

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Pubmed Data : Open Rheumatol J. 2014 ;8:77-81. Epub 2014 Oct 17. PMID: 25352926

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Pubmed Data : Nutrients. 2022 Sep 13 ;14(18). Epub 2022 Sep 13. PMID: 36145139

Article Published Date : Sep 12, 2022

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : C-Reactive Protein, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

[+]

A minor metabolite from Curcuma longa effective against metabolic syndrome.May 21, 2023

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Pubmed Data : Nutrients. 2022 Jan 18 ;14(3). Epub 2022 Jan 18. PMID: 35276778

Article Published Date : Jan 17, 2022

Study Type : Human Study

Additional Links

Substances : Curcumin, Frankincense

Diseases : Dysbiosis, Irritable Bowel Syndrome

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

[+]

Bioactive yoghurt containing curcumin and chlorogenic acid reduces inflammation in postmenopausal women.Nov 01, 2022

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Pubmed Data : Nutrients. 2022 Nov 2 ;14(21). Epub 2022 Nov 2. PMID: 36364884

Article Published Date : Nov 01, 2022

Study Type : Human Study

Additional Links

Substances : Chlorogenic Acid, Curcumin, Yoghurt

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Bioavailability Study: Piperine enhances the serum concentration, extent of absorption and bioavailability of curcumin in both rats and humans with no adverse effects.May 01, 1998

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Pubmed Data : Planta Med. 1998 May;64(4):353-6. PMID: 9619120

Article Published Date : May 01, 1998

Study Type : Human Study

Additional Links

Substances : Curcumin, Piperidines

[+]

Bioavailable turmeric extract is as effective as paracetamol in reducing pain and other symptoms of knee osteoarthritis.Jan 29, 2021

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Pubmed Data : Trials. 2021 Jan 30 ;22(1):105. Epub 2021 Jan 30. PMID: 33516238

Article Published Date : Jan 29, 2021

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Natural Substances Versus Drugs, Plant Extracts

[+]

Bioflavonoid therapy with curcumin and quercetin improves cadaveric renal transplantation in humans. Dec 15, 2005

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Pubmed Data : Transplantation. 2005 Dec 15;80(11):1556-9. PMID: 16371925

Article Published Date : Dec 15, 2005

Study Type : Human Study

Additional Links

Substances : Bioflavonoids, Curcumin, Quercetin

Diseases : Organ Transplantation: Kidney

[+]

Black turmeric and Aloe vera in the management of oral submucous fibrosis.Nov 30, 2021

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Pubmed Data : Asian Pac J Cancer Prev. 2021 Dec 1 ;22(12):3941-3947. Epub 2021 Dec 1. PMID: 34967575

Article Published Date : Nov 30, 2021

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Oral Submucous Fibrosis

Pharmacological Actions : Anti-Fibrotic

Additional Keywords : Plant Extracts

[+]

C. longa and B. serrata resin can relieve symptoms in patients with hand osteoarthritis.Nov 30, 2022

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Pubmed Data : Nutr J. 2021 11 13 ;20(1):91. Epub 2021 Nov 13. PMID: 34774052

Article Published Date : Jan 12, 2021

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Inflammation, Overweight

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

[+]

Curcuma longa L. extract supplementation leads to an increase in IL-10 and decreased myoglobin in recreational male runners after a half-marathon race.Jun 30, 2020

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Pubmed Data : Eur J Appl Physiol. 2020 Jul ;120(7):1531-1540. Epub 2020 May 2. PMID: 32361773

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2010 Jan 18. Epub 2010 Jan 18. PMID: 20080166

Article Published Date : Jan 18, 2010

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Alcohol Toxicity , Alcoholic Liver Disease

Pharmacological Actions : Hepatoprotective

[+]

Curcumin and Boswellia serrate has beneficial effects on glycoxidation and lipid peroxidation in chronically exercising master athletes.Nov 20, 2016

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Pubmed Data : Nutrients. 2016 Nov 21 ;8(11). Epub 2016 Nov 21. PMID: 27879642

Article Published Date : Nov 20, 2016

Study Type : Human Study

Additional Links

Substances : Curcumin, Frankincense

Diseases : Advanced Glycation End products (AGE), Lipid Peroxidation, Oxidative Stress

Pharmacological Actions : Antioxidants

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Curcumin and capsaicin might represent an alternative approach to protect against vitiligo progression.Jan 19, 2010

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Pubmed Data : Antioxid Redox Signal. 2010 Jan 19. Epub 2010 Jan 19. PMID: 20085492

Article Published Date : Jan 19, 2010

Study Type : Human Study

Additional Links

Substances : Capsaicin, Curcumin

Diseases : Vitiligo

[+]

Curcumin and lycopene treatment led to significant improvements in patients suffering from oral submucous fibrosis.Jul 29, 2018

Curcumin can effectively decrease the pathological results of osteoarthritis.Apr 21, 2022

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Pubmed Data : Altern Ther Health Med. 2022 Apr 22. Epub 2022 Apr 22. PMID: 35452417

Article Published Date : Apr 21, 2022

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Osteoarthritis

Pharmacological Actions : Anti-Inflammatory Agents, Chondroprotective

[+]

Curcumin can improve the mental health and quality of life of primiparous women postpartum due to its efficacy in reducing postpartum anxiety and depression.Apr 24, 2025

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Pubmed Data : J Clin Psychopharmacol. 2015 Aug ;35(4):406-10. PMID: 26066335

Article Published Date : Jul 31, 2015

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Depression

Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Natural Substance/Drug Synergy, Significant Treatment Outcome

Problem Substances : Antidepressants

[+]

Curcumin exhibits anti-pre-cancer activity by increasing levels of vitamins C and E, and preventing lipid peroxidation and DNA damage.Jan 01, 2010

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Pubmed Data : J Oral Sci. 2010;52(2):251-6. PMID: 20587949

Article Published Date : Jan 01, 2010

Study Type : Human Study

Additional Links

Substances : Curcumin, Vitamin C, Vitamin E

Diseases : DNA damage, Leukoplakia, Lichen Planus, Oxidative Stress, Precancerous Conditions

Pharmacological Actions : Antioxidants

[+]

Curcumin extract improves beta cell functions in obese patients with type 2 diabetes.Sep 30, 2024

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Pubmed Data : Nutr J. 2024 Oct 1 ;23(1):119. Epub 2024 Oct 1. PMID: 39354480

Article Published Date : Sep 30, 2024

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Hypoglycemic Agents, Pancreato Protective Agents

Additional Keywords : Plant Extracts

[+]

Curcumin gel and Aloe Vera gel are effective in improving oral submucous fibrosis symptoms.Jan 31, 2021

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Pubmed Data : Int J Clin Pharmacol Ther Toxicol. 1986 Dec;24(12):651-4. PMID: 3546166

Article Published Date : Dec 01, 1986

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Inflammation, Postoperative Recovery

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Curcumin has comparable efficacy to metronidazole in treating bacterial vaginosis while demonstrating superior effectiveness and fewer adverse effects in alleviating symptoms.Mar 02, 2025

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Pubmed Data : Sci Rep. 2025 Mar 3 ;15(1):7479. Epub 2025 Mar 3. PMID: 40032905

Article Published Date : Mar 02, 2025

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Vaginosis: Bacterial

Pharmacological Actions : Anti-Bacterial Agents

Additional Keywords : Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs

[+]

Curcumin has gall-bladder emptying properties. Jan 01, 2002

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Pubmed Data : Asia Pac J Clin Nutr. 2002;11(4):314-8. PMID: 12495265

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Pharm Investig. 2014 Jul ;4(3):138-41. PMID: 25126527

Article Published Date : Jun 30, 2014

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Stomatitis: Aphthous

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Antioxidants, Immunomodulatory

[+]

Curcumin has therapeutic effects in idiopathic inflammatory orbital pseudotumours.Sep 01, 2000

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Pubmed Data : Phytother Res. 2000 Sep;14(6):443-7. PMID: 10960899

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Diagn Res. 2014 Aug ;8(8):HC19-24. Epub 2014 Aug 20. PMID: 25302215

Article Published Date : Jul 31, 2014

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Bronchial Asthma

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Curcumin holds good promise in the treatment of oral submucous fibrosis in future.Apr 30, 2015

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Pubmed Data : J Oral Maxillofac Pathol. 2015 May-Aug;19(2):145-152. PMID: 26604488

Article Published Date : Apr 30, 2015

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Leukoplakia

[+]

Click here to read the entire abstract

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Pubmed Data : Eur J Appl Physiol. 2015 Sep ;115(9):1949-57. Epub 2015 Apr 29. PMID: 25921600

Article Published Date : Aug 31, 2015

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Muscle Damage: Exercise-Induced

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Curcumin is a safe and tolerable adjunct to FOLFOX chemotherapy in patients with metastatic colorectal cancer.May 26, 2019

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Pubmed Data : J Nutr. 2019 May 27. Epub 2019 May 27. PMID: 31132111

Article Published Date : May 26, 2019

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Cancer Metastasis, Colorectal Cancer

Pharmacological Actions : Chemotherapeutic

[+]

[+]

Curcumin is safe in humans up to 8,000 mg/day when take by mouth for 3 months and has chemopreventive properties. Jul 01, 2001

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Pubmed Data : Anticancer Res. 2001 Jul-Aug;21(4B):2895-900. PMID: 11712783

Article Published Date : Jul 01, 2001

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Tumors

Pharmacological Actions : Chemopreventive

Additional Keywords : Curcumin Safety, Herb Safety

[+]

Curcumin may be a safe and effective therapy for maintenance of remission in quiescent UC when given as adjunctive therapy along with mesalamine or sulfasalazine. Dec 31, 2011

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Pubmed Data : Cochrane Database Syst Rev. 2012 ;10:CD008424. Epub 2012 Oct 17. PMID: 23076948

Article Published Date : Dec 31, 2011

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Ulcerative Colitis

Additional Keywords : Complementary Alternative Medicine, Natural Substance/Drug Synergy, Randomized Controlled Trials As Topic

Problem Substances : Mesalamine, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

[+]

Curcumin may be effective in the improvement of cardiac injury after MI through immunomodulatory mechanisms.Dec 31, 2024

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Pubmed Data : J Clin Diagn Res. 2015 Aug ;9(8):ZC59-62. Epub 2015 Aug 1. PMID: 26436049

Article Published Date : Jul 31, 2015

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Radiation Induced Illness: Mucositis, Wound Healing

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Chemical: Chlorhexidine, Natural Substances Versus Chemicals, Significant Treatment Outcome

[+]

Curcumin phytosome has a beneficial effect in diabetic microangiopathy. Sep 01, 2011

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Pubmed Data : Panminerva Med. 2011 Sep ;53(3 Suppl 1):43-9. PMID: 22108476

Article Published Date : Sep 01, 2011

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Diabetic Microangiopathy

[+]

Therapeutic Actions : Exercise

Pharmacological Actions : Antioxidants, Superoxide Dismutase Up-regulation

[+]

Curcumin supplementation combined with high intensity interval training modulates serum irisin and lipid profile in obese women.Mar 31, 2025

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Pubmed Data : Contemp Clin Trials Commun. 2025 Apr ;44:101464. Epub 2025 Feb 21. PMID: 40092644

Pubmed Data : Int Urol Nephrol. 2022 Mar 26. Epub 2022 Mar 26. PMID: 35347555

Article Published Date : Mar 25, 2022

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Hemodialysis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Curcumin supplementation influences several biomarkers that may be associated with its antidepressant mechanisms of action.Dec 31, 2014

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Pubmed Data : Eur Neuropsychopharmacol. 2015 Jan ;25(1):38-50. Epub 2014 Dec 5. PMID: 25523883

Pubmed Data : Arch Pharm Res. 2024 Dec ;47(12):924-939. Epub 2024 Nov 28. PMID: 39607647

Article Published Date : Nov 30, 2024

Study Type : Human Study

Additional Links

Substances : Curcumin

Pharmacological Actions : Hypolipidemic, Renoprotective

[+]

[+]

Curcuminoids could be coadjuvants that might help fight breast cancer upon regular consumption.May 31, 2021

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Pubmed Data : J Assoc Physicians India. 2003 Nov ;51:1055-60. PMID: 15260388

Article Published Date : Oct 31, 2003

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Oral Cancer, Oral Submucous Fibrosis

Additional Keywords : Curcumin Safety, Plant Extracts

[+]

Click here to read the entire abstract

Pubmed Data : Eur J Dermatol. 2015 Jun 12. Epub 2015 Jun 12. PMID: 26066761

Article Published Date : Jun 11, 2015

Study Type : Human Study

Additional Links

Substances : Curcumin

Therapeutic Actions : Photodynamic therapy

[+]

[+]

Efficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter study.Dec 31, 2013

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Pubmed Data : Clin Interv Aging. 2014 ;9:451-8. Epub 2014 Mar 20. PMID: 24672232

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Pubmed Data : Drugs Context. 2025 ;14. Epub 2025 Jul 9. PMID: 40661790

Article Published Date : Dec 31, 2024

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Acne

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Evaluation of efficacy of curcumin along with lycopene and piperine in the management of oral submucous fibrosis.Jun 30, 2019

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Pubmed Data : Contemp Clin Dent. 2019 Jul-Sep;10(3):531-541. PMID: 32308333

Article Published Date : Jun 30, 2019

Study Type : Human Study

Additional Links

Substances : Curcumin, Lycopene, Piperine

Diseases : Fibrosis

Pharmacological Actions : Anti-Fibrotic

[+]

[+]

Improvement of sulphur mustard-induced chronic pruritus, quality of life and antioxidant status by curcumin: results of a randomised, double-blind, placebo-controlled trial.Sep 30, 2012

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Pubmed Data : Br J Nutr. 2012 Oct ;108(7):1272-9. Epub 2011 Nov 18. PMID: 22099425

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Pubmed Data : Phytother Res. 2020 Apr ;34(4):896-903. Epub 2019 Dec 1. PMID: 31788880

Article Published Date : Mar 31, 2020

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Anxiety, Depression, Peripheral Neuropathies

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Nanocurcumin has a potentiating anti-inflammatory effect when combined with standard COVID-19 treatment.Dec 31, 2022

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Pubmed Data : J Clin Gastroenterol. 2021 Sep 1 ;55(8):702-708. PMID: 32889959

Article Published Date : Aug 31, 2021

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Ulcerative Colitis

Pharmacological Actions : Gastrointestinal Agents

Additional Keywords : Natural Substance/Drug Synergy

[+]

Optimized curcumin, pomegranate extract, and methylsulfonylmethane reduce acute, systemic inflammatory response to a half-marathon race. Jun 30, 2020

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Pubmed Data : Altern Ther Health Med. 2020 Jul 1. Epub 2020 Jul 1. PMID: 32619204

Click here to read the entire abstract

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Pubmed Data : Front Pharmacol. 2021 ;12:669362. Epub 2021 May 28. PMID: 34122090

Article Published Date : Dec 31, 2020

Study Type : Human Study

Additional Links

Substances : Curcumin, Piperine

Diseases : Coronavirus Infection

Additional Keywords : Morbidity, Mortality, Risk Reduction

[+]

[+]

Reduction of atherogenic risk in patients with type 2 diabetes by curcuminoid extract: a randomized controlled trial.Jan 31, 2014

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Pubmed Data : J Nutr Biochem. 2014 Feb ;25(2):144-50. Epub 2013 Nov 6. PMID: 24445038

Article Published Date : Jan 31, 2014

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Abdominal Obesity (Midsection Fat), C-Reactive Protein: Diabetes-Associated, Diabetes, Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2: Prevention, HDL: Low, Inflammation, Insulin Resistance, Obesity, Obesity: Abdominal

Pharmacological Actions : Anti-atherogenic, Anti-Inflammatory Agents

[+]

Regular endurance exercise combined with daily curcumin ingestion may reduce LV afterload to a greater extent than monotherapy with either intervention alone in postmenopausal women.May 31, 2012

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Pubmed Data : Am J Hypertens. 2012 Jun ;25(6):651-6. Epub 2012 Mar 15. PMID: 22421908

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Pubmed Data : Phytother Res. 2016 Jun 8. Epub 2016 Jun 8. PMID: 27270872

Article Published Date : Jun 07, 2016

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Pubmed Data : Clin Lab. 2024 Jan 1 ;70(1). PMID: 38213217

Article Published Date : Dec 31, 2023

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Thalassemia

Additional Keywords : Gene Expression Regulation

[+]

Synergistic effects of turmeric, strawberry and broccoli in improving lipid profile in adult patients with hypercholesterolemia.Oct 31, 2024

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Pubmed Data : Pak J Biol Sci. 2024 Nov ;27(12):587-593. PMID: 39731428

Article Published Date : Oct 31, 2024

Study Type : Human Study

Additional Links

Substances : Broccoli, Curcumin, Strawberry

Diseases : Hypercholesterolemia

Additional Keywords : Natural Substance Synergy

[+]

Targeting inflammation through diet in patients after spinal cord injury could help with depressive symptoms. Dec 31, 2014

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Pubmed Data : J Neuroinflammation. 2015 ;12(1):204. Epub 2015 Nov 6. PMID: 26545369

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Pubmed Data : J Neuropathol Exp Neurol. 2022 May 13. Epub 2022 May 13. PMID: 35556131

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Pubmed Data : Adv Exp Med Biol. 2021 ;1308:25-35. PMID: 33861434

Article Published Date : Dec 31, 2020

Study Type : Human Study

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Substances : Curcumin

Diseases : Diabetes Mellitus: Type 2, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

The effect of curcumin supplementation on clinical outcomes and inflammatory markers in patients with ulcerative colitis.Apr 30, 2020

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Pubmed Data : Phytother Res. 2020 May ;34(5):1123-1133. Epub 2019 Dec 4. PMID: 31802559

The findings support the potential efficacy of curcumin for the treatment of osteoarthritis of the knee.Dec 22, 2021

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Pubmed Data : Nutrients. 2021 Dec 23 ;14(1). Epub 2021 Dec 23. PMID: 35010916

Article Published Date : Dec 22, 2021

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Analgesics

Additional Keywords : Medication Reduction

[+]

The immunomodulatory effects of curcumin on forkhead box O1 and microRNA-873 in patients with osteoarthritis.Oct 05, 2024

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Pubmed Data : Cancer Invest. 2025 Mar ;43(3):173-182. Epub 2025 Mar 27. PMID: 40145664

Article Published Date : Feb 28, 2025

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Breast Cancer, Chemotherapy and Radiation Toxicity, Dermatitis

Pharmacological Actions : Radioprotective

[+]

Theracurmin Super effectively reduced oxidative stress before and after exercise.Feb 28, 2025

Twelve-week use of curcumin complex or its combination with boswellic acid reduces pain-related symptoms in patients with osteoarthritis.Jan 08, 2018

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Pubmed Data : BMC Complement Altern Med. 2018 Jan 9 ;18(1):7. Epub 2018 Jan 9. PMID: 29316908

Article Published Date : Jan 08, 2018

Study Type : Human Study

Additional Links

Substances : Curcumin, Frankincense

Diseases : Osteoarthritis

Pharmacological Actions : Analgesics

Additional Keywords : Natural Substance Synergy

[+]

Vitamin D3 and curcuminoids (turmeric) stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients. Jul 01, 2009

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Pubmed Data : J Alzheimers Dis. 2009 Jul;17(3):703-17. PMID: 19433889

Article Published Date : Jul 01, 2009

Study Type : Human Study

Additional Links

Substances : Curcumin, Vitamin D

Diseases : Alzheimer's Disease

Additional Keywords : Disease Regression

[+]

Whey protein, omega-3 fatty acids and polyphenols with electrical muscle stimulation increases muscle strength in elderly adults with limited mobility.Jun 22, 2020

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Pubmed Data : Nutrients. 2020 Jun 23 ;12(6). Epub 2020 Jun 23. PMID: 32585837

Article Published Date : Jun 22, 2020

Study Type : Human Study

Additional Links

Substances : Curcumin, Omega-3 Fatty Acids, Polyphenols, Rutin, Whey

Diseases : Sarcopenia

Therapeutic Actions : Electric Stimulation

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Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults.Mar 31, 2023

Comparing efficacy of curcumin with other treatment modalities in oral submucous fibrosis management.Dec 31, 2023

Curcumin and Curcuma longa extract may improve symptoms and inflammation levels in people with arthritis.Dec 31, 2021

Curcumin in the treatment of inflammation and oxidative stress responses in traumatic brain injury.Dec 31, 2023

Curcumin is likely to be of benefit in mild-to-moderate COVID-19 patients.Jan 13, 2023

Curcumin led to a decrease in the serum CRP and TNF-alpha levels in patients with knee osteoarthritis.Jul 03, 2025

Curcumin may have the potential to enhance cardiometabolic health by reducing hyperglycemia, insulin resistance, and serum TC levels in women with PCOS.Feb 28, 2025

Curcumin supplementation significantly reduces anthropometric indices.Apr 30, 2023

Evaluating the efficacy of curcumin in the management of oral potentially malignant disorders.Dec 31, 2023

Safety and efficacy of curcumin in the treatment of ulcerative colitis.Dec 31, 2024

The effect of highly bioavailable forms of curcumin on lipoprotein(a) plasma levels.Apr 16, 2025

The effectiveness of curcumin, resveratrol, and silymarin on MASLD.Nov 30, 2024

The effects of curcumin plus piperine co-administration on inflammation and oxidative stress.Mar 28, 2024

The efficacy of curcumin application to melanoma in mice.Jul 31, 2024

The findings of this systematic review and meta-analysis support the potential effect of curcumin on the management of NAFLD.Dec 31, 2024

These findings suggest that curcumin may be used as an adjunct therapy in individuals with oxidative stress.Nov 30, 2019

A review of the beneficial effects of antioxidants on Helicobacter pylori eradication.Nov 30, 2018

Anti-inflammatory effects of oral supplementation with curcumin.Aug 08, 2021

Curcumin administration reduces depressive symptoms in patients with major depression.Nov 26, 2015

Curcumin as an ajuvant treatment of depression: mechanisms of action and application prospects.Dec 31, 2019

Curcumin for depression: a meta-analysis.Aug 18, 2019

Curcumin is a safe, natural bioactive substance that can effectively prevent and treat oral mucositis.Dec 31, 2020

Curcumin may provide great potential effects against diabetic kidney disease. Dec 31, 2020

Curcumin or combined curcuminoids are effective in lowering the fasting blood glucose concentrations of individuals with dysglycemia.Sep 15, 2017

Curcumin supplementation has favorable effect on metabolic markers and anthropometric parameters in patients with NAFLD.Dec 31, 2019

Curcuminoids may have some beneficial effects on knee pain and quality of life in patients with knee osteoarthritis.Mar 31, 2017

Effects of Curcuma as an adjunct therapy on periodontal disease.Oct 31, 2021

Efficacy and safety of adjuvant curcumin therapy in ulcerative colitisJan 24, 2022

Efficacy and safety of dietary polyphenols in rheumatoid arthritis.Dec 31, 2022

Efficacy and safety of turmeric dietary supplementation on proteinuria in CKD.Apr 30, 2022

Impact of exercise intervention with or without curcumin supplementation on body fat composition, glucose, and lipid metabolism in obese adults.Feb 28, 2025

Influence of phytosomal curcumin on anthropometric indices for nonalcoholic fatty liver disease.Dec 26, 2024

Meta-analysis of randomized controlled trials of 4 weeks or longer suggest that curcumin may afford some protection against oxidative stress.Jan 11, 2018

Meta-analysis of the effect of curcumin supplementation on skeletal muscle damage status.Dec 31, 2023

Meta-analysis: curcumin down-regulates inteleukin-6. Jul 04, 2016

Photodynamic therapy for oral candidiasis in human clinical trials.Jul 31, 2025

Potential therapeutic effects of curcumin on glycemic and lipid profile in uncomplicated type 2 diabetes.Jan 26, 2021

Protective effects of curcumin on epileptic rodent models by alleviating oxidative stress and inflammation.Dec 31, 2024

The effect of curcumin as an adjunct in the treatment of chronic periodontitis.Oct 31, 2021

The potential of curcumin for treating spinal cord injury.May 03, 2022

The results of this study suggest that the administration of curcumin supplements may be a beneficial intervention for enhancing glycemic indices.Nov 30, 2024

These RCTs provide scientific evidence that supports the efficacy of turmeric extract and curcumin in the treatment of arthritis.Jul 31, 2016

This meta-analysis of RCTs suggested a significant effect of curcumin in lowering circulating TNF-α concentration.Mar 25, 2016

Use of curcumin in achieving clinical and endoscopic remission in ulcerative colitis.Jan 09, 2018

Cancer stem cells as a prognostic biomarker and therapeutic target using curcumin/ piperine extract for multiple myeloma.Sep 30, 2022

A bioavailable form of curcumin is well-tolerated and can positively influence weight management in overweight people.Oct 31, 2015

A combination of curcumin and fennel essential oil significantly improved symptoms and quality of life in IBS patients over 30 days.May 31, 2016

A combination of curcumin and melatonin supplemented using an oral cosmetic vehicle has the capacity to decrease the level of periodontal pathogenic bacteria.Oct 30, 2024

A combination of hydroxytyrosol, omega-3 fatty acids and curcumin improves pain and inflammation among early stage breast cancer patients.Mar 31, 2019

A combination of Saw Palmetto, Nettle, Curcumin and Quercetin significantly improves treatment outcome of prulifloxacin in bacterial prostatitis patients. Jun 01, 2009

A complex of curcumin and phosphatidylcholine is effective in reducing the symptoms of ostearthritis.Dec 01, 2010

A curcumin extract is appropriate for the care of patients with joint problems and may also contribute to the regeneration of cartilage.Dec 31, 2013

A curcumin formula decreased the median polyp number in familial adenomatous polyposis patients. Nov 21, 2022

A daily dose of 3.6 g curcumin achieves pharmacologically efficacious levels in the colorectum with negligible distribution of curcumin outside the gut.Jan 01, 2005

A hot water extract of C. longa may help to improve systemic glucose metabolism in people with chronic low-grade inflammation.Sep 12, 2022

A minor metabolite from Curcuma longa effective against metabolic syndrome.May 21, 2023

A pilot study to examine the effects of an anti-inflammatory supplement on eicosanoid derivatives in patients with chronic kidney disease.Jul 31, 2017

A polyherbal cream application of curcumin had a HPV clearance rate of 81.3%. Dec 31, 2012

A standardized preparation of curcuminoids compares favorably with atorvastatin on endothelial dysfunction in association with reductions in inflammatory cytokines and markers of oxidative stress. Jan 01, 2008

A supplement containing huperzine A and curcumin in dementia patients and individuals with mild cognitive impairment had beneficial effects.Dec 31, 2017

A topical preparation of curcumin successfully decreased the markers of lactational mastitis such as pain, breast tension and erythema within 72 hours of administration.Aug 31, 2014

Add-on treatment with curcumin has antidepressive effects in thai patients with major depression.Dec 31, 2017

Addition of curcumin on top of the standard anti-helicobacter regimen in patients with PU is safe and improves dyspepsia symptoms.Jun 27, 2016

Addition of curcumin to mesalamine therapy was superior to placebo and mesalamine in inducing clinical and endoscopic remission in patients with mild-to-moderate active UC.Jul 31, 2015

Adiponectin levels in myeloma patients after curcumin supplementation.Dec 31, 2024

An exclusion diet and nutraceutical therapy has significant therapeutic effects in juvenile Crohn's disease. Jun 01, 2009

Beneficial effects of curcumin supplementation were observed in decreasing disease activity scores and severity of cirrhosis in patients with cirrhosis.Feb 02, 2020

Beneficial effects on abdominal bloating with an innovative food-grade formulation of Curcuma longa and Boswellia serrata extracts in subjects with irritable bowel syndrome.Jan 17, 2022

Bioactive yoghurt containing curcumin and chlorogenic acid reduces inflammation in postmenopausal women.Nov 01, 2022

Bioavailability Study: Piperine enhances the serum concentration, extent of absorption and bioavailability of curcumin in both rats and humans with no adverse effects.May 01, 1998

Bioavailable turmeric extract is as effective as paracetamol in reducing pain and other symptoms of knee osteoarthritis.Jan 29, 2021

Bioflavonoid therapy with curcumin and quercetin improves cadaveric renal transplantation in humans. Dec 15, 2005

Curcumin

View the Evidence:
3743 Abstracts with Curcumin Research