Curcumin

Name	AC	CK
Oxidative Stress	256	561
Inflammation	165	505
Diabetes Mellitus: Type 2	52	177
Breast Cancer	122	176
Depression	30	171
Alzheimer's Disease	91	164
Obesity	40	122
Colorectal Cancer	56	117
Nonalcoholic fatty liver disease (NAFLD)	22	109
Ulcerative Colitis	22	109
Colon Cancer	80	108
Lipid Peroxidation	42	108
Cancers: All	97	104
Prostate Cancer	69	104
Chemically-Induced Liver Damage	50	100
Coronavirus Infection	34	100
Osteoarthritis	24	99
Liver Cancer	64	97
Lung Cancer	73	92
Osteoarthritis: Knee	12	86
Lipopolysaccharide-Induced Toxicity	61	83
Cancers: Drug Resistant	65	80
DNA damage	46	80
Rheumatoid Arthritis	17	77
Pancreatic Cancer	36	74
Wound Healing	41	73
C-Reactive Protein	8	67
Chronic Kidney Disease (CKD)	9	65
Neurodegenerative Diseases	44	64
Inflammatory Bowel Diseases	33	63
Colitis	27	60
Insulin Resistance	22	60
Parkinson's Disease	42	60
Endothelial Dysfunction	19	57
Liver Fibrosis	35	57
Brain Inflammation	37	55
Cancer Metastasis	41	55
Oral Cancer	28	54
Glioblastoma	27	53
Multiple Myeloma	17	52
Aging	20	51
Alcohol Toxicity	20	51
Hyperglycemia	14	51
Oral Mucositis	5	51
Head and Neck Cancer	22	50
Helicobacter Pylori Infection	15	47
Melanoma	38	46
Metabolic Syndrome X	8	45
Polycystic Ovary Syndrome	8	45
Spinal Cord Injuries	11	45
Arthritis	15	44
Cardiovascular Diseases	21	44
Depressive Disorder	5	44
Hypertension	12	44
Gastric Cancer	31	43
Muscle Damage: Exercise-Induced	6	43
Chemotherapy-Induced Toxicity: Cisplatin	28	42
Diabetic Nephropathy	15	42
Oral Submucous Fibrosis	6	42
Psoriasis	16	42
Tumors	22	42
Atherosclerosis	22	41
Radiation Induced Illness	23	40
Periodontitis	8	39
Proteinuria	7	39
Asthma	18	38
Arsenic Poisoning	12	37
Brain: Oxidative Stress	11	37
Cholestasis	7	37
HIV Infections	20	37
Periodontal Diseases	8	37
Brain Injury: Traumatic	10	36
Skin Cancer	19	35
Cervical Cancer	30	34
Cancers: Multi-Drug Resistant	33	33
Cognitive Decline/Dysfunction	14	33
Diabetic Complications	20	33
Thalassemia	6	33
Advanced Glycation End products (AGE)	8	32
Breast Cancer: Triple Negative	22	32
Glioma	22	32
Headache: Migraine	4	32
Hyperlipidemia	16	32
Myocardial Infarction	12	32
Ovarian Cancer	29	32
Alcoholic Liver Disease	8	31
Dysmenorrhea	4	31
Leukoplakia	4	31
Multiple Sclerosis	16	31
Premenstrual syndrome	4	31
Benzo[a]pyrene-induced Toxicity	18	30
Bladder Cancer	25	30
Chemical Weapon Agent Injury: Sulfur Mustard	3	30
Diabetes Mellitus: Type 1	17	30
Diabetes: Cardiovascular Illness	12	30
High Fat Diet	15	30
Irritable Bowel Syndrome	8	30
Leukemia	28	30
Human Papillomavirus (HPV)	14	29
Myocardial Ischemia	11	29
Pesticide Toxicity	17	29
Squamous cell carcinoma	22	29
Anxiety	8	28
Brain Ischemia	15	28
Memory Disorders	14	28
Lung Injury: Acute	14	27
Malaria	20	27
Aflatoxicosis	14	26
Fatty Liver	10	26
Epilepsy	15	25
High Cholesterol	9	25
Pulmonary Fibrosis	13	25
Carcinoma: Non-Small-Cell Lung	19	24
Cholesterol: Oxidation	11	24
Diabetic Neuropathy	3	24
Familial Adenomatous Polyposis	4	24
Postmenopausal Disorders	4	24
Stress	8	24
Aging: Brain	8	23
Cerebral Ischemia	13	23
Chronic Pain	8	23
Colitis: Ulcerative	2	23
Gingivitis	5	23
Staphylococcus aureus infection	15	23
Dental Plaque	4	22
Diabetic Retinopathy	10	22
Kidney Damage	11	22
Prostatic Hyperplasia	2	22
Uveitis	4	22
Aluminum Toxicity	12	21
Spondylitis: Ankylosing	1	21
Cadmium Poisoning	11	20
Cholesterol: LDL/HDL ratio	2	20
Colon Polyps	6	20
HDL: Low	2	20
Infertility: Male	6	20
Liver Cirrhosis	7	20
Liver Damage	12	20
Macular Degeneration	10	20
Overweight	2	20
Postoperative Recovery	2	20
Smoldering multiple myeloma (SMM)	2	20
Testicular Injury: Chemical/Metal Induced	10	20
Acetaminophen (Tylenol) Toxicity	11	19
Bisphenol Toxicity	9	19
Cystic Fibrosis	9	19
Dyslipidemias	6	19
Metabolic Diseases	6	19
Promyelocytic leukemia	19	19
Cataract	11	18
Chemotherapy-Induced Toxicity: Doxorubicin	11	18
Hypercholesterolemia	5	18
Ischemia	10	18
Neuropathic Pain	10	18
Nicotine/Tobacco Toxicity	11	18
Anxiety Disorders	5	17
Brain Cancer	7	17
Dementia	5	17
Diabetes: Oxidative Stress	10	17
Endotoxemia	9	17
Leukemia: Chronic myelogenous leukemia (CML)	7	17
Liver Damage: Aflatoxin-Induced	9	17
Systemic Lupus Erythematosus	4	17
Chemotherapy and Radiation Toxicity	4	16
Chemotherapy-Induced Toxicity: Bleomycin	8	16
Coronary Artery Disease	4	16
Crohn's Disease	7	16
Iron Overload	7	16
Neuroblastoma	12	16
Stroke: Ischemic	6	16
Triglycerides: Elevated	4	16
Allergies	12	15
Brain: Microglial Activation	12	15
Cholesterol: High	4	15
Lymphoma	12	15
Osteoporosis	10	15
Radiation Induced Illness: Mucositis	4	15
Sepsis	10	15
Stroke: Attenuation/Recovery	9	15
Chronic Obstructive Pulmonary Disease	5	14
Dejerine-Sottas Disease	3	14
Depression	3	14
Dysbiosis	4	14
Endometriosis	12	14
Esophageal Cancer	12	14
Fatigue: Excercise-Induced	3	14
Gastrointestinal Inflammation	7	14
Glaucoma	5	14
Hypoxia	10	14
Leukemia: Chronic Lymphocytic Leukemia (CLL)	5	14
Muscle Soreness: Exercise-Induced	3	14
Peripheral Neuropathies	3	14
Prostatitis: Chronic	3	14
Arthritis: Rheumatoid	4	13
Chemotherapy-Induced Toxicity: Cyclophosphamide	8	13
Fibrosis	3	13
Gastric Ulcer	7	13
Gastrointestinal polyps	3	13
Heart Failure	8	13
Liver Damage: Drug-Induced	8	13
Muscle Atrophy	8	13
Myocardial Fibrosis	7	13
Pancreatitis	8	13
Plasma Cell Dyscrasias	2	13
Sarcopenia	3	13
Seizures	6	13
Thyroid Diseases	3	13
Acute Myeloid Leukemia	8	12
Allergic Rhinitis	2	12
Chemotherapy-Induced Toxicity	8	12
Chemotherapy-Induced Toxicity: Gentamicin	6	12
Cirrhosis	2	12
Coronavirus Disease (Covid-19)	3	12
Drug-Induced Toxicity	6	12
Escherichia coli Infections	10	12
Eye Diseases	3	12
Insulin: Low	2	12
Left Ventricular Dysfunction	2	12
Liver Disease	7	12
Maculopathy: Age-Related	2	12
Middle Cerebral Artery Occlusion (MCAO)	6	12
Pain	6	12
Precancerous Conditions	2	12
Prostate: PSA Doubling	3	12
Vitiligo	3	12
Allergic Airway Diseases	6	11
Autoimmune Diseases	11	11
Brain Injury: Hippocampal Damage	7	11
Chemical Exposure	6	11
Diabetes	2	11
Diabetes Mellitus: Type 2: Prevention	2	11
Diabetes: Cognitive Dysfunction	6	11
Dry Eye Syndromes	2	11
Immune Disorders: Low Immune Function	6	11
Mitochondrial Dysfunction	8	11
Neurofibromatosis	2	11
Phthalate Toxicity	6	11
Prostate Cancer: Metastatic	2	11
Pruritus	2	11
Schizophrenia	2	11
ALT: Elevated	1	10
Abdominal Obesity (Midsection Fat)	1	10
Biliary Dyskinesia	1	10
Brain Damage	6	10
Breast Cancer: Metastatic	8	10
Bronchial Asthma	1	10
C-Reactive Protein: Diabetes-Associated	1	10
Cardiac Hypertrophy	7	10
Chemical Weapon Agent Injury	1	10
Chemotherapy	7	10
Coronary Bypass Surgery	1	10
Dementia with Lewy bodies (DLB)	1	10
Dental Care	1	10
Diabetic Microangiopathy	1	10
Diarrhea	1	10
Dyspepsia	1	10
Epileptic Seizures	4	10
Gallbladder Disease	1	10
Gammopathy: Monoclonal	1	10
Gulf War Syndrome	1	10
Halitosis	1	10
Hemodialysis	1	10
Hemoglobinopathies	1	10
Hot Flash	1	10
Hyperalgesia	5	10
Influenza A	7	10
Insulin Disorders	1	10
Intestinal Polyps	5	10
Lead Poisoning	6	10
Leukemia: B-Cell	1	10
Lichen Planus	1	10
Lichen Sclerosus	1	10
Lupus Erythematosus: Cutaneous	1	10
Maculopathy	1	10
Mastitis	1	10
Monoclonal Gammopathies	1	10
Muscle Damage	1	10
Obesity: Abdominal	1	10
Orbital Pseudotumor	1	10
Organ Transplantation: Kidney	1	10
Peptic Ulcer	1	10
Plasma beta amyloid protein concentrations: elevated	1	10
Plasma catalase activities: elevated	1	10
Proctitis	1	10
Proctocolitis: Ulcerative	1	10
Quality of Life: Poor	1	10
Respiratory Infections: Infants & Children	1	10
Respiratory Tract Infections	1	10
Salivary amylase levels: elevated	1	10
Sciatic Nerve Crush Injury	5	10
Soluble cell adhesion molecules (sCAMs): elevated	1	10
Spinal Cord Inflammation	1	10
Stomatitis: Aphthous	1	10
Stroke	7	10
T-Cell Lymphoma: Cutaneous	1	10
Ulcer: Aphthous	1	10
Urinary Tract Infections	1	10
Vertigo	1	10
Cachexia	5	9
Drug Toxicity: Methotrexate	5	9
Gastrointestinal Cancer	6	9
Gram-Negative Bacterial Infections	4	9
Hepatic Steatosis	5	9
High Fructose Diet	5	9
Nasopharyngeal Cancer	8	9
Organ Transplantation	6	9
Parasitic Diseases	5	9
Thrombosis	6	9
Burns	4	8
Chemotherapy-Induced Kidney Damage	4	8
Copper Toxicity	5	8
Diabetes: Kidney Function	4	8
Fluoride Toxicity	4	8
Herpes Simplex Virus Type 2	4	8
Kidney Damage: Drug-Induced	4	8
Kidney Fibrosis	4	8
Leukemia: Acute myelogenous leukemia (AML)	6	8
Lymphoma: B-Cell	8	8
Memory Disorders: Drug-Induced	4	8
Prediabetes	3	8
Pseudomonas aeruginosa	7	8
Sperm Quality: Low	4	8
Testicular Diseases	4	8
Thyroid Cancer	8	8
Acute lymphoblastic leukemia (ALL)	5	7
Cancer Stem Cells	7	7
Chemotherapy-Induced Toxicity: 5-fluorouracil	4	7
Colon Cancer: Prevention	4	7
Colorectal Cancer: Prevention	4	7
Dengue	6	7
Drug-Induced Toxicity: Indomethacin	4	7
Endometrial Cancer	5	7
Hypersensitivity	4	7
Kidney Damage: Chemically-Induced	4	7
Leishmaniasis	7	7
Liver Steatosis	4	7
Mesothelioma	5	7
Non-Small-Cell Lung Carcinoma	7	7
Osteosarcoma	7	7
Staphylococcus aureus: Methicillin-resistant (MRSA)	6	7
Amyloidosis	3	6
Amyotrophic Lateral Sclerosis	5	6
Aneurysm: Aortic	3	6
Antibiotic Toxicity	3	6
Arteriosclerosis	4	6
Autism Spectrum Disorders	4	6
Brain Edema	3	6
Candida Infection	6	6
Cholangiocarcinoma	3	6
Cytomegalovirus Infections	4	6
Excitotoxicity	6	6
Flukes	3	6
Fungal Infection	5	6
Huntington Disease	5	6
Immune Dysregulation: TH1/TH2 imbalance	3	6
Influenza	4	6
Intestinal Cancer	3	6
Iron Poisoning	4	6
Leptin: Elevated Levels	4	6
Lung Damage	3	6
Memory Loss	3	6
Peripheral Nerve Diseases	3	6
Wound Healing: Delayed	3	6
Acute Myeloid Leukemia: Stem Cell	1	5
Acute T cell Leukemias	5	5
Bacterial Vaginosis	1	5
Bone Diseases	2	5
Brain Diseases	4	5
Cardiomyopathy	3	5
Cholera	1	5
Chronic Myeloid Leukemia	5	5
Diabetes Mellitus: Type 1: Prevention	3	5
Dioxin Toxicity	3	5
Epstein-Barr Virus Infections	4	5
Gallstones	3	5
Gastrointestinal Infections	1	5
Glomerulosclerosis	3	5
Hepatitis C	5	5
Homocysteine: Elevated	3	5
Intestinal Permeability	3	5
Intracerebral Hemorrhage	3	5
Klebsiella Infections	3	5
Leukemia: Monocytic	3	5
Liver Cancer: Prevention	3	5
Pituitary Tumours	4	5
Pneumonia	3	5
Radiation Associated Toxicity: Cobalt-60	1	5
Retinal Diseases	4	5
Retinoblastoma	5	5
Smoking	3	5
Yeast Infection: Vaginal	1	5
Amyotrophic lateral sclerosis (ALS)	4	4
Angiostrongylus Cantonensis Infection	2	4
Anti-Malarial Drug Toxicity	2	4
Aortic Stenosis	2	4
Blood Sugar Problems	2	4
Blood-Brain-Barrier Disorders	2	4
Breast Cancer Stem Cells	4	4
Burkitt Lymphoma	3	4
Cachexia: Cancer	2	4
Charcot-Marie-Tooth Disease	2	4
Chemotherapy Induced Myelotoxicity	2	4
Chemotherapy-Induced Toxicity: Adriamycin	2	4
Demyelinating Diseases	2	4
Diabetes: Liver Disease	2	4
Diabetic Neuropathies	2	4
Drug-Induced Toxicity: Cyclosporine	2	4
Drug-Induced Toxicity: Haloperidol	2	4
Encephalitis: Japanese	3	4
Encephalopathies	2	4
Eosinophilic Meningitis	2	4
Fever	2	4
Fibrosis: Liver	2	4
Gastritis	2	4
Giardiasis	3	4
Hearing Loss	2	4
Hepatitis B	4	4
Hepatitis: Lectin-Induced (concanavalin)	2	4
Hepatoma	3	4
Herbicide Toxicity	2	4
Hypercapnia	2	4
Hyperthyroidism	2	4
Intestinal Ischemia	2	4
Learning disorders	2	4
Left Ventricular Hypertrophy	2	4
Leptin Resistance	2	4
Liver Diseases	4	4
Lung Inflammation	2	4
Lupus Erythematosus: Systemic	3	4
Morphine Tolerance/Dependence	2	4
Myelodysplastic Syndromes	2	4
Neuropathies	2	4
Oral Cancer: Prevention	3	4
Organ Transplantation: Heart	2	4
Organ Transplantation: Pancreatic Islet Cells	3	4
Ovarian Diseases	2	4
Pancreatic Cancer: Metastatic	1	4
Peripheral Arterial Disease	2	4
Polycystic Kidney Diseases	2	4
Prenatal Chemical Exposures	2	4
Prion Diseases	3	4
Respiratory Syncytial Virus Infections	3	4
Retinitis Pigmentosa	3	4
Rhabdomyosarcoma	3	4
Sickle Cell Anemia	2	4
Tobacco Toxicity	2	4
Tongue Cancer	3	4
Acinetobacter baumannii infection	3	3
Acne	2	3
Acrylamide-induced toxicity	2	3
Adiponectin: Low Levels	2	3
Adult T-cell leukemia/lymphoma (ATL)	2	3
Anaphylaxis	2	3
Bacterial Infections and Mycoses	2	3
Bladder Cancer: Prevention	2	3
Brain Hypoxia	2	3
Candida Albicans	3	3
Cardiomegaly	2	3
Chemotherapy-Induced Toxicity: Mitomycin-C	2	3
Chemotherapy-Induced Toxicity: Tamoxifen	2	3
Circulating Free Fatty Acids: Elevated	2	3
Corticosteroid-Induced Toxicity	3	3
Cortisol: High	2	3
Degenerative Disk Disease	2	3
Diabetes: Cataract	2	3
Diabetes: Glycation/A1C	2	3
Endothelial Damage	2	3
Enterococcus Infections	3	3
Fibrosarcoma	2	3
Fructose-Induced Toxicity	2	3
Gastroenteritis	2	3
Heavy Metal Toxicity	2	3
Hemangioendothelioma	1	3
Human T-Cell Lymphotrophic Virus type 1 associated disease	2	3
Hydrogen Peroxide Induced Toxicity	3	3
Hypothyroidism	2	3
Immune Dysregulation: TH1 dominance	2	3
Inflammation: Neutrophil-Mediated	2	3
Kidney Cancer	3	3
Kidney Diseases	2	3
Leiomyosarcoma	3	3
Leukemia: Acute promyelocytic leukemia	2	3
Lung Cancer Stem Cell	2	3
Mitochondrial Diseases	2	3
Mucositis	2	3
Mycobacterium abscessus	2	3
NSAID-induced toxicity	2	3
Nerve Injuries	2	3
Obsessive-Compulsive Disorder	2	3
Organ Transplantation: Liver	2	3
Otitis media	2	3
Parkinsonism	2	3
Post-Traumatic Stress Disorders (PTSD)	2	3
Radiation	2	3
Respiratory Distress Syndrome	2	3
Schistosomiasis	2	3
Scleroderma	2	3
Sjogren's Syndrome	2	3
Skin Diseases: Photo-Aging	2	3
Subarachnoid hemorrhage	2	3

Name	AC	CK
Anti-Inflammatory Agents	541	1468
Antioxidants	551	1176
Apoptotic	521	660
Antiproliferative	424	586
Neuroprotective Agents	304	585
Tumor Necrosis Factor (TNF) Alpha Inhibitor	187	450
NF-kappaB Inhibitor	290	432
Antineoplastic Agents	290	402
Hepatoprotective	160	367
Interleukin-6 Downregulation	96	249
Chemopreventive	156	248
Antidepressive Agents	32	183
Hypoglycemic Agents	41	179
Hypolipidemic	43	177
Renoprotective	71	177
Immunomodulatory	89	172
Enzyme Inhibitors	102	163
Analgesics	29	149
Cardioprotective	72	147
Cell cycle arrest	122	145
Anticarcinogenic Agents	93	144
Anti-metastatic	107	142
Chemosensitizer	119	135
Chemoprotective Agents	49	124
Cyclooxygenase 2 Inhibitors	78	122
Interleukin-1 beta downregulation	61	122
Antiviral Agents	90	115
Chemotherapeutic	73	114
Anti-Bacterial Agents	57	107
Anti-Apoptotic	68	106
Gastrointestinal Agents	28	101
Malondialdehyde Down-regulation	24	98
Superoxide Dismutase Up-regulation	24	85
Anti-Fibrotic	31	74
Radioprotective	31	72
MicroRNA modulator	45	69
Tumor Suppressor Protein p53 Upregulation	49	68
Nrf2 activation	40	66
Interleukin-10 upregulation	11	54
Anti-Angiogenic	37	53
Matrix metalloproteinase-2 (MMP-2) inhibitor	35	50
Antimicrobial	17	44
Genoprotective	19	38
Matrix metalloproteinase-9 (MMP-9) inhibitor	27	38
Anti-Anxiety Agents	8	37
Anticholesteremic Agents	7	37
Nitric Oxide Inhibitor	19	37
Interleukin-8 downregulation	17	34
Radiosensitizer	27	34
Cytoprotective	19	32
Cholagogues and Choleretics	3	30
Heme oxygenase-1 up-regulation	19	30
Prophylactic Agents	10	30
Angiogenesis Inhibitors	23	29
Interleukin-4 downregulation	7	28
Vascular Endothelial Growth Factor A Inhibitor	20	28
Gastroprotective	14	27
Wnt/β-catenin signaling pathway modulation	19	27
Prostaglandin PGE2 downregulation	14	26
Anti-Infective Agents	5	25
Anticonvulsants	12	25
Anti-Ulcer Agents	9	24
Interleukin-17 downregulation	4	24
Vascular Endothelial Growth Factor Inhibitors	14	24
Anti-Tumor	10	22
Bcl-2 protein down-regulation	19	22
Insulin Sensitizers	8	22
Antihypertensive Agents	8	20
Heat Shock Protein Inducer	13	20
SIRT1 Activator	7	20
Matrix metalloproteinase-3 (MMP-3) inhibitor	7	19
Pancreato Protective Agents	7	18
Regenerative	10	18
Anti-Proliferative	15	17
Antimutagenic Agents	14	17
Epidermal growth factor receptor (EGFR) inhibitor	15	17
Proteasome Inhibitors	12	17
Anti-Glycation Agents	3	16
Antimalarials	14	16
Antifungal Agents	14	15
Antinoceceptive	8	15
Immunostimulatory	10	15
P21 Activation	6	15
Vasoprotective	4	15
Anti-Allergic Agents	10	14
Anti-atherogenic	3	13
Autophagy Up-regulation	11	13
Histone deacetylase inhibitor	13	13
Antiparasitic Agents	8	12
Chondroprotective	3	12
Iron Chelating Agents	2	12
Nitric Oxide Enhancer	2	12
Transforming growth factor beta (TGF-β) inhibitor	7	12
Adiponectin upregulation	2	11
Caspase-3 Activation	7	11
Immunomodulatory: Th17 downregulation	2	11
Neurogenesis	7	11
STAT3 Inhibitor	9	11
Dermatologic Agents	1	10
Immunosuppressive Agents	7	10
Interleukin-10 downregulation	6	10
Interleukin-22 Downregulation	1	10
Osteoprotective	7	10
Phosphorylase Kinase Inhibitors	1	10
VEGFR3 inhibition	1	10
anti-inflammatory	1	10
Cytotoxic	9	9
Oncogene Suppressor	6	9
Acetylcholinesterase Inhibitor	5	8
Angiotensin-Converting Enzyme Inhibitors	5	8
Bax/Bcl2 ratio: Increase	4	8
Cyclooxygenase Inhibitors	7	8
Lipoxygenase Inhibitors	8	8
Multidrug Resistance Gene Modulators	7	8
Wnt/β-catenin pathway down-regulation	7	8
Cardiovascular Agents	4	7
Cyclooxygenase 1 Inhibitor	7	7
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	5	7
Leishmanicidal	7	7
Protein Kinase Inhibitors	6	7
Anti-Cachexic Agents	3	6
Autophagy Inhibitors	4	6
Detoxifier	4	6
Neuritogenic	4	6
Telomerase Inhibitor	6	6
Vasodilator Agents	3	6
Adiponectin Down-Regulation	1	5
Anti-Platelet	4	5
Anti-Retroviral Agents	1	5
Bax/Bcl2 Ratio: Decrease	3	5
Heme oxygenase-1 inducer	4	5
Interferon Gamma Reducer	3	5
Interleukin-18 down-regulation	3	5
Platelet Aggregation Inhibitors	3	5
Spermicidal Activity	1	5
Anti-Asthmatic Agents	2	4
Anti-pyretic	2	4
Antispasmodic	2	4
Cell Differentiation Inducer	3	4
Glutathione Upregulation	2	4
Interleukin-2 Downregulation	2	4
Interleukin-4 upregulation	2	4
Monoaminergic	2	4
Neurorestorative	2	4
Photosensitizing Agents	3	4
Vascular Cell Adhesion Molecule-1 Inhibitor	4	4
Vitamin D Receptor (VDR) Modulator	3	4
AMP-activated protein kinase modulation	2	3
Chelating Agents	2	3
Cyclin D1 Down-Regulation	3	3
Drug synergy	2	3
Estrogen Receptor Modulators	2	3
Excitatory Amino Acid Agonists	2	3
Interleukin-5 downregulation	2	3
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	3
Paraptosis	3	3
Postaglandin PGE2 downregulation	3	3
AKT-mammalian target of rapamycin (mTOR) pathway inhibitor	2	2
Adenosine deaminase inhibitor	1	2
Alpha-glucosidase inhibitor	2	2
Analgesics: Non-Narcotic	1	2
Analgesics: Opioid	1	2
Androgen Antagonists	1	2
Angiogenesis Inducing Agents	1	2
Angiogenesis Modulating Agents	1	2
Anti-Androgen	1	2
Anti-Inflammatory Agents: Non-Steroidal	1	2
Anti-thrombotic	1	2
Antigiardial agents	1	2
Antioxidant Effects	2	2
Anxiolytic	1	2
Calcium Channel Blockers	2	2
Catalase Up-Regulation	1	2
Cholinesterase Inhibitors	1	2
Fertility Agents: Male	1	2
Gluconeogenesis Inhibitor	2	2
Glutathione S-transferase Inhibitor	2	2
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor	2	2
HIV Protease Inhibitors	2	2
Heat Shock Protein Down-Regulation	2	2
High-mobility group box-1 (HMGB1) inhibitor	1	2
Histamine H2 Antagonists	2	2
Hypoxia-inducible factor-1 (HIF-1) inhibitor	1	2
Insulin Receptor Modulator	1	2
Insulin-Like Growth Factor Inhibition/Downregulation	2	2
Insulin-releasing	1	2
Interleukin-1 alpha downregulation	1	2
Interleukin-21 downregulation	1	2
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	1	2
Matrix Metalloproteinases Inhibitors	1	2
Metal Chelation: Copper	1	2
Muscarinic Agonists	1	2
Myorelaxant	1	2
NF-E2-Related Factor-2 (Nrf2) Modulator	2	2
Neuromodulatory	1	2
Phase II Detoxification Enzyme Inducer	1	2
Prostaglandin Antagonists	1	2
Proton Pump Inhibitor	1	2
Quorum Sensing Inhibition	2	2
Redox Modulator	1	2
Remyelination	1	2
Schistosomicides	1	2
Serotonin Agonists	1	2
Survivin Down-Regulation	2	2
Thromboxane (TXB) Inhibitors	1	2
Vascular Endothelial Growth Factor C Inhibitor	1	2
Vascular Endothelial Growth Factor Regulator	1	2
Vascular smooth muscle cell (VSMC) inhibitor	2	2
Xanthine oxidase inhibitor	2	2
Akt-SREBP-1 activater	1	1
Aldose reductase inhibitor	1	1
Alpha-amylase inhibitor	1	1
Anti Inflammatory	1	1
Anti-Adipogenic	1	1
Anti-HIV Agents	1	1
Anti-Infective Agents: Urinary	1	1
Anti-fungal effects	1	1
Antibiotics: Antifungal	1	1
Antidepressive Agents: Second-Generation	1	1
Antilipolytic	1	1
Antimycobacterial	1	1
Appetite Suppresant	1	1
Brain-derived neurotrophic factor modulator	1	1
Calcium/calmodulin dependent protein kinase II inhibitor	1	1
Cannabinoid Receptor Antagonist/Inverse Agonist	1	1
Carbonyl Reductase 1Inhibitor	1	1
Caspase-9 Activation	1	1
Enzyme Activators	1	1
Enzyme Inhibitors: Pancreatic Lipase	1	1
Eryptotic	1	1
Expectorants	1	1
Fatty Acid Synthesis Inhibitors	1	1
Glucose transporter-1 (GLUT1) expression down-regulation	1	1
Glucose transporter-2 (GLUT2) expression down-regulation	1	1
Glucose transporter-5 (GLUT5) expression down-regulation	1	1
Glyoxalase 1 inhibitor	1	1
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Inhibitor	1	1
Hypomethylating	1	1
Hypotensive	1	1
Inhibitor of Nuclear Factor Kappa-B Kinase (IKK)	1	1
Insect Repellents	1	1
Interferon-gamma (IFN-gamma) inducer	1	1
Interleukin-12 downregulation	1	1
Interleukin-6 upregulation	1	1
Intracellular adhesion molecule-1 (ICAM-1)	1	1
Leptin Down-Regulation	1	1
Leukotriene B4 downregulation	1	1
Leukotriene C4 Downregulation	1	1
Maspin (Protease Inhibitor) Up-Regulation	1	1
Mast Cell Activation Inhibitor	1	1
Matrix Metalloproteinase-7 (MMP-7) Inhibitor	1	1
Matrix metalloproteinase-14 (MMP-14) inhibitor	1	1
Matrix metalloproteinase-16 (MMP-16) inhibitor	1	1
Matrix metalloproteinase-17 (MMP-17) inhibitor	1	1
Neuroplasticity enhancement	1	1
Nonpeptidyl Inhibitors	1	1
Osteogenic	1	1
P-glycoprotein Inhibitors	1	1
P16 Activation	1	1
PI3K-AKT inhibitor	1	1
PRL-3 Down-Regulation	1	1
Palmitoylation Inhibitors	1	1
Phosphodiesterase Inhibitors	1	1
Phospholipase D Inhibitors	1	1
Proliferative	1	1
Protease Inhibitors	1	1
Reactive Oxygen Species (ROS) attenuation	1	1
Receptor activator of NF-κB (RANK) gene expression	1	1
S-phase kinase associated protein 2 inhibition	1	1
STAT3-NFκB Signaling: downregulation	1	1
Secretagogue	1	1
Transient Receptor Potential Melastatin 2 Inhibition	1	1
Trypanocidal Agents	1	1
Tumor Necrosis Factor (TNF) Alpha Enhancer	1	1
apoptosis	1	1

[+]

Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults.Mar 31, 2023

Click here to read the entire abstract

Pubmed Data : Cytokine. 2023 Apr ;164:156144. Epub 2023 Feb 15. PMID: 36804260

Article Published Date : Mar 31, 2023

Study Type : Meta Analysis, Review

Additional Links

Substances : Curcumin

Diseases : C-Reactive Protein, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Curcumin and Curcuma longa extract may improve symptoms and inflammation levels in people with arthritis.Dec 31, 2021

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Pubmed Data : Pharmacol Res. 2017 Sep 16. Epub 2017 Sep 16. PMID: 28928074

Article Published Date : Sep 15, 2017

Study Type : Meta Analysis, Review

Additional Links

Substances : Curcumin, Curcuminoids

Diseases : Hyperglycemia

Pharmacological Actions : Hypoglycemic Agents

[+]

Curcumin supplementation has favorable effect on metabolic markers and anthropometric parameters in patients with NAFLD.Dec 31, 2019

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Pubmed Data : Open Rheumatol J. 2014 ;8:77-81. Epub 2014 Oct 17. PMID: 25352926

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Pubmed Data : Nutrients. 2022 Sep 13 ;14(18). Epub 2022 Sep 13. PMID: 36145139

Article Published Date : Sep 12, 2022

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : C-Reactive Protein, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

[+]

A minor metabolite from Curcuma longa effective against metabolic syndrome.May 21, 2023

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[+]

Bioactive yoghurt containing curcumin and chlorogenic acid reduces inflammation in postmenopausal women.Nov 01, 2022

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Pubmed Data : Nutrients. 2022 Nov 2 ;14(21). Epub 2022 Nov 2. PMID: 36364884

Article Published Date : Nov 01, 2022

Study Type : Human Study

Additional Links

Substances : Chlorogenic Acid, Curcumin, Yoghurt

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Bioavailability Study: Piperine enhances the serum concentration, extent of absorption and bioavailability of curcumin in both rats and humans with no adverse effects.May 01, 1998

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Pubmed Data : Planta Med. 1998 May;64(4):353-6. PMID: 9619120

Article Published Date : May 01, 1998

Study Type : Human Study

Additional Links

Substances : Curcumin, Piperidines

[+]

Bioavailable turmeric extract is as effective as paracetamol in reducing pain and other symptoms of knee osteoarthritis.Jan 29, 2021

Click here to read the entire abstract

Pubmed Data : Trials. 2021 Jan 30 ;22(1):105. Epub 2021 Jan 30. PMID: 33516238

Article Published Date : Jan 29, 2021

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Natural Substances Versus Drugs, Plant Extracts

[+]

Bioflavonoid therapy with curcumin and quercetin improves cadaveric renal transplantation in humans. Dec 15, 2005

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Pubmed Data : Transplantation. 2005 Dec 15;80(11):1556-9. PMID: 16371925

Article Published Date : Dec 15, 2005

Study Type : Human Study

Additional Links

Substances : Bioflavonoids, Curcumin, Quercetin

Diseases : Organ Transplantation: Kidney

[+]

Black turmeric and Aloe vera in the management of oral submucous fibrosis.Nov 30, 2021

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Pubmed Data : Asian Pac J Cancer Prev. 2021 Dec 1 ;22(12):3941-3947. Epub 2021 Dec 1. PMID: 34967575

Article Published Date : Nov 30, 2021

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Oral Submucous Fibrosis

Pharmacological Actions : Anti-Fibrotic

Additional Keywords : Plant Extracts

[+]

C. longa and B. serrata resin can relieve symptoms in patients with hand osteoarthritis.Nov 30, 2022

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Pubmed Data : Nutr J. 2021 11 13 ;20(1):91. Epub 2021 Nov 13. PMID: 34774052

Article Published Date : Jan 12, 2021

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Inflammation, Overweight

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

[+]

Curcuma longa L. extract supplementation leads to an increase in IL-10 and decreased myoglobin in recreational male runners after a half-marathon race.Jun 30, 2020

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Pubmed Data : Eur J Appl Physiol. 2020 Jul ;120(7):1531-1540. Epub 2020 May 2. PMID: 32361773

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Pubmed Data : J Ethnopharmacol. 2010 Jan 18. Epub 2010 Jan 18. PMID: 20080166

Article Published Date : Jan 18, 2010

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Alcohol Toxicity , Alcoholic Liver Disease

Pharmacological Actions : Hepatoprotective

[+]

Curcumin and Boswellia serrate has beneficial effects on glycoxidation and lipid peroxidation in chronically exercising master athletes.Nov 20, 2016

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Pubmed Data : Nutrients. 2016 Nov 21 ;8(11). Epub 2016 Nov 21. PMID: 27879642

Article Published Date : Nov 20, 2016

Study Type : Human Study

Additional Links

Substances : Curcumin, Frankincense

Diseases : Advanced Glycation End products (AGE), Lipid Peroxidation, Oxidative Stress

Pharmacological Actions : Antioxidants

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Curcumin and capsaicin might represent an alternative approach to protect against vitiligo progression.Jan 19, 2010

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Pubmed Data : Antioxid Redox Signal. 2010 Jan 19. Epub 2010 Jan 19. PMID: 20085492

Article Published Date : Jan 19, 2010

Study Type : Human Study

Additional Links

Substances : Capsaicin, Curcumin

Diseases : Vitiligo

[+]

Curcumin and lycopene treatment led to significant improvements in patients suffering from oral submucous fibrosis.Jul 29, 2018

[+]

Curcumin could reverse the development of depression and enhance the outcome of antidepressants treatment in major depressive disorder.Jul 31, 2015

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Pubmed Data : J Clin Psychopharmacol. 2015 Aug ;35(4):406-10. PMID: 26066335

Article Published Date : Jul 31, 2015

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Depression

Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Natural Substance/Drug Synergy, Significant Treatment Outcome

Problem Substances : Antidepressants

[+]

Curcumin exhibits anti-pre-cancer activity by increasing levels of vitamins C and E, and preventing lipid peroxidation and DNA damage.Jan 01, 2010

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Pubmed Data : J Oral Sci. 2010;52(2):251-6. PMID: 20587949

Article Published Date : Jan 01, 2010

Study Type : Human Study

Additional Links

Substances : Curcumin, Vitamin C, Vitamin E

Diseases : DNA damage, Leukoplakia, Lichen Planus, Oxidative Stress, Precancerous Conditions

Pharmacological Actions : Antioxidants

[+]

Curcumin extract improves beta cell functions in obese patients with type 2 diabetes.Sep 30, 2024

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Pubmed Data : Nutr J. 2024 Oct 1 ;23(1):119. Epub 2024 Oct 1. PMID: 39354480

Article Published Date : Sep 30, 2024

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Hypoglycemic Agents, Pancreato Protective Agents

Additional Keywords : Plant Extracts

[+]

Curcumin gel and Aloe Vera gel are effective in improving oral submucous fibrosis symptoms.Jan 31, 2021

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Pubmed Data : Int J Clin Pharmacol Ther Toxicol. 1986 Dec;24(12):651-4. PMID: 3546166

Article Published Date : Dec 01, 1986

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Inflammation, Postoperative Recovery

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Curcumin has gall-bladder emptying properties. Jan 01, 2002

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Pubmed Data : Asia Pac J Clin Nutr. 2002;11(4):314-8. PMID: 12495265

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Pharm Investig. 2014 Jul ;4(3):138-41. PMID: 25126527

Article Published Date : Jun 30, 2014

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Stomatitis: Aphthous

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Antioxidants, Immunomodulatory

[+]

Curcumin has therapeutic effects in idiopathic inflammatory orbital pseudotumours.Sep 01, 2000

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Pubmed Data : Phytother Res. 2000 Sep;14(6):443-7. PMID: 10960899

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Diagn Res. 2014 Aug ;8(8):HC19-24. Epub 2014 Aug 20. PMID: 25302215

Article Published Date : Jul 31, 2014

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Bronchial Asthma

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Curcumin holds good promise in the treatment of oral submucous fibrosis in future.Apr 30, 2015

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Pubmed Data : J Oral Maxillofac Pathol. 2015 May-Aug;19(2):145-152. PMID: 26604488

Article Published Date : Apr 30, 2015

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Leukoplakia

[+]

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Pubmed Data : J Oral Rehabil. 2018 Jun 16. Epub 2018 Jun 16. PMID: 29908031

Article Published Date : Jun 15, 2018

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Postoperative Recovery

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents

[+]

Curcumin is safe and efficacious in treating major depressive disorder.Jul 05, 2013

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

Curcumin protects DNA damage in a chronically arsenic-exposed population of West Bengal.Jan 07, 2010

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Pubmed Data : Hum Exp Toxicol. 2010 Jan 7. Epub 2010 Jan 7. PMID: 20056736

Article Published Date : Jan 07, 2010

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Arsenic Poisoning

[+]

Curcumin reduces arsenic-induced DNA damage in human subjects. Mar 01, 2011

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Pubmed Data : Eur J Cancer Prev. 2011 Mar;20(2):123-31. PMID: 21332098

Click here to read the entire abstract

Pubmed Data : Int J Sports Med. 2014 Jun ;35(6):469-75. Epub 2013 Oct 28. PMID: 24165958

Article Published Date : May 31, 2014

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Oxidative Stress

Therapeutic Actions : Exercise

Pharmacological Actions : Antioxidants, Superoxide Dismutase Up-regulation

[+]

Curcumin supplementation effectively mitigates inflammation in patients suffering from chronic SM-induced cutaneous complications. Oct 31, 2012

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Pubmed Data : Ann Clin Biochem. 2012 Nov ;49(Pt 6):580-8. Epub 2012 Oct 4. PMID: 23038702

Pubmed Data : Arch Pharm Res. 2024 Dec ;47(12):924-939. Epub 2024 Nov 28. PMID: 39607647

Article Published Date : Nov 30, 2024

Study Type : Human Study

Additional Links

Substances : Curcumin

Pharmacological Actions : Hypolipidemic, Renoprotective

[+]

Click here to read the entire abstract

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Effectiveness of Curcuma longa extract for the treatment of symptoms and effusion-synovitis of knee osteoarthritis.Nov 30, 2020

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Pubmed Data : Ann Intern Med. 2020 Dec 1 ;173(11):861-869. Epub 2020 Sep 15. PMID: 32926799

Click here to read the entire abstract

Pubmed Data : J Cell Physiol. 2020 Dec 28. Epub 2020 Dec 28. PMID: 33372280

Article Published Date : Dec 27, 2020

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Coronavirus Infection

Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation

[+]

Improvement of sulphur mustard-induced chronic pruritus, quality of life and antioxidant status by curcumin: results of a randomised, double-blind, placebo-controlled trial.Sep 30, 2012

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Pubmed Data : Br J Nutr. 2012 Oct ;108(7):1272-9. Epub 2011 Nov 18. PMID: 22099425

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Pubmed Data : Front Pharmacol. 2021 ;12:669362. Epub 2021 May 28. PMID: 34122090

Article Published Date : Dec 31, 2020

Study Type : Human Study

Additional Links

Substances : Curcumin, Piperine

Diseases : Coronavirus Infection

Additional Keywords : Morbidity, Mortality, Risk Reduction

[+]

[+]

Reduction of atherogenic risk in patients with type 2 diabetes by curcuminoid extract: a randomized controlled trial.Jan 31, 2014

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Pubmed Data : J Nutr Biochem. 2014 Feb ;25(2):144-50. Epub 2013 Nov 6. PMID: 24445038

Article Published Date : Jan 31, 2014

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Abdominal Obesity (Midsection Fat), C-Reactive Protein: Diabetes-Associated, Diabetes, Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2: Prevention, HDL: Low, Inflammation, Insulin Resistance, Obesity, Obesity: Abdominal

Pharmacological Actions : Anti-atherogenic, Anti-Inflammatory Agents

[+]

Regular endurance exercise combined with daily curcumin ingestion may reduce LV afterload to a greater extent than monotherapy with either intervention alone in postmenopausal women.May 31, 2012

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Pubmed Data : Am J Hypertens. 2012 Jun ;25(6):651-6. Epub 2012 Mar 15. PMID: 22421908

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Pubmed Data : Phytother Res. 2016 Jun 8. Epub 2016 Jun 8. PMID: 27270872

Article Published Date : Jun 07, 2016

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Pubmed Data : Clin Lab. 2024 Jan 1 ;70(1). PMID: 38213217

Article Published Date : Dec 31, 2023

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Thalassemia

Additional Keywords : Gene Expression Regulation

[+]

Synergistic effects of turmeric, strawberry and broccoli in improving lipid profile in adult patients with hypercholesterolemia.Oct 31, 2024

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Pubmed Data : Pak J Biol Sci. 2024 Nov ;27(12):587-593. PMID: 39731428

Article Published Date : Oct 31, 2024

Study Type : Human Study

Additional Links

Substances : Broccoli, Curcumin, Strawberry

Diseases : Hypercholesterolemia

Additional Keywords : Natural Substance Synergy

[+]

Targeting inflammation through diet in patients after spinal cord injury could help with depressive symptoms. Dec 31, 2014

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Pubmed Data : J Neuroinflammation. 2015 ;12(1):204. Epub 2015 Nov 6. PMID: 26545369

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Pubmed Data : J Neuropathol Exp Neurol. 2022 May 13. Epub 2022 May 13. PMID: 35556131

Pubmed Data : J Strength Cond Res. 2020 Oct 9. Epub 2020 Oct 9. PMID: 33044367

Article Published Date : Oct 08, 2020

Study Type : Human Study

Additional Links

Substances : Curcumin, Fenugreek, Fiber

Diseases : Fatigue: Excercise-Induced

Therapeutic Actions : Exercise

[+]

This study produced additional data on curcumin as a treatment for cancer, with a high response rate and good tolerability.Jan 15, 2016

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Pubmed Data : Oncology. 2016 Jan 16. Epub 2016 Jan 16. PMID: 26771576

Article Published Date : Jan 15, 2016

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Prostate Cancer, Prostate Cancer: Metastatic

Pharmacological Actions : Chemoprotective Agents, Chemotherapeutic

Additional Keywords : Drug: Docetaxel

Problem Substances : Prednisone

[+]

This study provides preliminary evidence that curcumin and maritime pine may help alleviate symptoms of Gulf War Illness.Jan 02, 2021

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Pubmed Data : Int J Environ Res Public Health. 2021 03 3 ;18(5). Epub 2021 Mar 3. PMID: 33802272

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2019 Jun 28 ;238:111882. Epub 2019 Apr 13. PMID: 30991137

Article Published Date : Jun 27, 2019

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Asthma

Additional Keywords : Medication Reduction, Phytotherapy

[+]

Turmeric and curcumin are therapeutic as topical agents in cancer therapy. Feb 28, 1987

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Pubmed Data : Tumori. 1987 Feb 28;73(1):29-31. PMID: 2435036

Article Published Date : Feb 28, 1987

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Skin Cancer

[+]

Turmeric has the ability to reduce weight, decrease body fat percentage, lower systolic blood pressure, and relieve anxiety for young, obese and overweight females.Feb 20, 2020

Pubmed Data : Curr Mol Pharmacol. 2024 Jan 26. Epub 2024 Jan 26. PMID: 38284733

Article Published Date : Jan 25, 2024

Study Type : Human In Vitro

Additional Links

Substances : Berberine, Curcumin

Diseases : Systemic Lupus Erythematosus

Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory

[+]

Curcumin and citral in combination may be a useful therapeutic intervention for breast cancer.Aug 31, 2015

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Pubmed Data : Mol Med Rep. 2015 Dec 28. Epub 2015 Dec 28. PMID: 26718010

Article Published Date : Dec 27, 2015

Study Type : Human In Vitro

Additional Links

Substances : Curcumin

Diseases : Advanced Glycation End products (AGE), Endothelial Dysfunction, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Glycation Agents, Anti-Inflammatory Agents, Antioxidants

[+]

Article Published Date : Aug 29, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Curcumin, Moringa oleifera

Diseases : Epilepsy

Pharmacological Actions : Anticonvulsants

[+]

Combination of curcumin and ginkgolide B inhibits cystogenesis by regulating multiple signaling pathways.Feb 28, 2021

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Pubmed Data : Mol Med Rep. 2021 Mar ;23(3). Epub 2021 Jan 26. PMID: 33495815

Article Published Date : Feb 28, 2021

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Curcumin, Ginkgo biloba

Diseases : Polycystic Kidney Diseases

Pharmacological Actions : Renoprotective

Additional Keywords : Natural Substance Synergy

[+]

Combination of curcumin and piperine synergistically improves pain-like behaviors in mouse models of pain.Oct 22, 2022

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Pubmed Data : Int J Dermatol. 2011 Sep ;50(9):1058-66. PMID: 22126865

Article Published Date : Aug 31, 2011

Study Type : Human: Case Report

Additional Links

Substances : Curcumin

Diseases : Wound Healing

Pharmacological Actions : Regenerative

[+]

Use of curcumin in multiple myeloma patients intolerant of steroid therapy.Mar 31, 2020

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Pubmed Data : Clin Case Rep. 2020 Apr ;8(4):739-744. Epub 2020 Feb 25. PMID: 32274049

Click here to read the entire abstract

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[+]

A combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis.Jan 01, 2010

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Pubmed Data : Food Chem Toxicol. 2010 Jan;48(1):390-5. Epub 2009 Oct 25. PMID: 19861145

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Substances : Catechin , Curcumin, Green Tea

Diseases : Colon Cancer, Colorectal Cancer

Pharmacological Actions : Anticarcinogenic Agents, Apoptotic, Chemopreventive

Additional Keywords : Drug Synergy

[+]

A combination of curcumin with piperine exhibited profound cardioprotection compared to curcumin alone-treated group.Dec 31, 2016

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Pubmed Data : Indian J Pharmacol. 2017 Jan-Feb;49(1):65-70. PMID: 28458425

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Curcumin, Piperine

Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide

Pharmacological Actions : Cardioprotective, Chemoprotective Agents

[+]

A combination of nutrients improves cognitive functioning while decreasing Alzheimer disease neuropathology in an animal model.Jan 01, 2010

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Pubmed Data : PLoS One. 2010;5(11):e14015. Epub 2010 Nov 17. PMID: 21103342

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Substances : Alpha-Lipoic Acid, B-complex, Curcumin, EGCG (Epigallocatechin gallate), Folic Acid , NAC (N-acetyl-L-cysteine), Piperine, Vitamin C

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

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Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults.Mar 31, 2023

Curcumin and Curcuma longa extract may improve symptoms and inflammation levels in people with arthritis.Dec 31, 2021

Curcumin in the treatment of inflammation and oxidative stress responses in traumatic brain injury.Dec 31, 2023

Curcumin is likely to be of benefit in mild-to-moderate COVID-19 patients.Jan 13, 2023

Curcumin supplementation significantly reduces anthropometric indices.Apr 30, 2023

The effects of curcumin plus piperine co-administration on inflammation and oxidative stress.Mar 28, 2024

These findings suggest that curcumin may be used as an adjunct therapy in individuals with oxidative stress.Nov 30, 2019

A review of the beneficial effects of antioxidants on Helicobacter pylori eradication.Nov 30, 2018

Anti-inflammatory effects of oral supplementation with curcumin.Aug 08, 2021

Curcumin administration reduces depressive symptoms in patients with major depression.Nov 26, 2015

Curcumin as an ajuvant treatment of depression: mechanisms of action and application prospects.Dec 31, 2019

Curcumin for depression: a meta-analysis.Aug 18, 2019

Curcumin is a safe, natural bioactive substance that can effectively prevent and treat oral mucositis.Dec 31, 2020

Curcumin may provide great potential effects against diabetic kidney disease. Dec 31, 2020

Curcumin or combined curcuminoids are effective in lowering the fasting blood glucose concentrations of individuals with dysglycemia.Sep 15, 2017

Curcumin supplementation has favorable effect on metabolic markers and anthropometric parameters in patients with NAFLD.Dec 31, 2019

Curcuminoids may have some beneficial effects on knee pain and quality of life in patients with knee osteoarthritis.Mar 31, 2017

Effects of Curcuma as an adjunct therapy on periodontal disease.Oct 31, 2021

Efficacy and safety of adjuvant curcumin therapy in ulcerative colitisJan 24, 2022

Efficacy and safety of dietary polyphenols in rheumatoid arthritis.Dec 31, 2022

Efficacy and safety of turmeric dietary supplementation on proteinuria in CKD.Apr 30, 2022

Meta-analysis of randomized controlled trials of 4 weeks or longer suggest that curcumin may afford some protection against oxidative stress.Jan 11, 2018

Meta-analysis: curcumin down-regulates inteleukin-6. Jul 04, 2016

Potential therapeutic effects of curcumin on glycemic and lipid profile in uncomplicated type 2 diabetes.Jan 26, 2021

The effect of curcumin as an adjunct in the treatment of chronic periodontitis.Oct 31, 2021

The potential of curcumin for treating spinal cord injury.May 03, 2022

These RCTs provide scientific evidence that supports the efficacy of turmeric extract and curcumin in the treatment of arthritis.Jul 31, 2016

This meta-analysis of RCTs suggested a significant effect of curcumin in lowering circulating TNF-α concentration.Mar 25, 2016

Use of curcumin in achieving clinical and endoscopic remission in ulcerative colitis.Jan 09, 2018

Cancer stem cells as a prognostic biomarker and therapeutic target using curcumin/ piperine extract for multiple myeloma.Sep 30, 2022

A bioavailable form of curcumin is well-tolerated and can positively influence weight management in overweight people.Oct 31, 2015

A combination of curcumin and fennel essential oil significantly improved symptoms and quality of life in IBS patients over 30 days.May 31, 2016

A combination of hydroxytyrosol, omega-3 fatty acids and curcumin improves pain and inflammation among early stage breast cancer patients.Mar 31, 2019

A combination of Saw Palmetto, Nettle, Curcumin and Quercetin significantly improves treatment outcome of prulifloxacin in bacterial prostatitis patients. Jun 01, 2009

A complex of curcumin and phosphatidylcholine is effective in reducing the symptoms of ostearthritis.Dec 01, 2010

A curcumin extract is appropriate for the care of patients with joint problems and may also contribute to the regeneration of cartilage.Dec 31, 2013

A curcumin formula decreased the median polyp number in familial adenomatous polyposis patients. Nov 21, 2022

A daily dose of 3.6 g curcumin achieves pharmacologically efficacious levels in the colorectum with negligible distribution of curcumin outside the gut.Jan 01, 2005

A hot water extract of C. longa may help to improve systemic glucose metabolism in people with chronic low-grade inflammation.Sep 12, 2022

A minor metabolite from Curcuma longa effective against metabolic syndrome.May 21, 2023

A pilot study to examine the effects of an anti-inflammatory supplement on eicosanoid derivatives in patients with chronic kidney disease.Jul 31, 2017

A polyherbal cream application of curcumin had a HPV clearance rate of 81.3%. Dec 31, 2012

A standardized preparation of curcuminoids compares favorably with atorvastatin on endothelial dysfunction in association with reductions in inflammatory cytokines and markers of oxidative stress. Jan 01, 2008

A supplement containing huperzine A and curcumin in dementia patients and individuals with mild cognitive impairment had beneficial effects.Dec 31, 2017

A topical preparation of curcumin successfully decreased the markers of lactational mastitis such as pain, breast tension and erythema within 72 hours of administration.Aug 31, 2014

Add-on treatment with curcumin has antidepressive effects in thai patients with major depression.Dec 31, 2017

Addition of curcumin on top of the standard anti-helicobacter regimen in patients with PU is safe and improves dyspepsia symptoms.Jun 27, 2016

Addition of curcumin to mesalamine therapy was superior to placebo and mesalamine in inducing clinical and endoscopic remission in patients with mild-to-moderate active UC.Jul 31, 2015

An exclusion diet and nutraceutical therapy has significant therapeutic effects in juvenile Crohn's disease. Jun 01, 2009

Beneficial effects of curcumin supplementation were observed in decreasing disease activity scores and severity of cirrhosis in patients with cirrhosis.Feb 02, 2020

Beneficial effects on abdominal bloating with an innovative food-grade formulation of Curcuma longa and Boswellia serrata extracts in subjects with irritable bowel syndrome.Jan 17, 2022

Bioactive yoghurt containing curcumin and chlorogenic acid reduces inflammation in postmenopausal women.Nov 01, 2022

Bioavailability Study: Piperine enhances the serum concentration, extent of absorption and bioavailability of curcumin in both rats and humans with no adverse effects.May 01, 1998

Bioavailable turmeric extract is as effective as paracetamol in reducing pain and other symptoms of knee osteoarthritis.Jan 29, 2021

Bioflavonoid therapy with curcumin and quercetin improves cadaveric renal transplantation in humans. Dec 15, 2005

Black turmeric and Aloe vera in the management of oral submucous fibrosis.Nov 30, 2021

C. longa and B. serrata resin can relieve symptoms in patients with hand osteoarthritis.Nov 30, 2022

Chelidonium and turmeric root extract have a therapeutic effect on upper abdominal pain due to functional disorders of the biliary system. Aug 15, 1999

Chemopreventive synergism between green tea extract and curcumin in patients with potentially malignant oral disorders.Apr 30, 2020

Co-administration of iron and bioavailable curcumin reduces levels of systemic markers of inflammation and oxidative stress.Feb 07, 2022

Combining nano-curcumin with catechin improves COVID-19-infected patient's inflammatory conditions.Aug 31, 2023

Curcuma longa extract improves serum inflammatory markers and mental health in healthy participants who are overweight.Jan 12, 2021

Curcuma longa L. extract supplementation leads to an increase in IL-10 and decreased myoglobin in recreational male runners after a half-marathon race.Jun 30, 2020

Curcuma-based nutritional supplements and risk of age-related macular degeneration.Oct 23, 2024

Curcumin acts as an adjuvant to imatinib in decreasing the NO levels and may help in the treatment of CML patients.Aug 15, 2011

Curcumin alleviates ethanol-induced oxidative damage in liver cells. Jan 18, 2010

Curcumin and Boswellia serrate has beneficial effects on glycoxidation and lipid peroxidation in chronically exercising master athletes.Nov 20, 2016

Curcumin and capsaicin might represent an alternative approach to protect against vitiligo progression.Jan 19, 2010

Curcumin and lycopene treatment led to significant improvements in patients suffering from oral submucous fibrosis.Jul 29, 2018

Curcumin and piperine supplementation before and after exercise can attenuate some, but not all, aspects of muscle damage.Feb 28, 2017

Curcumin appears safe and effective in maintaining remission in patients with quiescent ulcerative colitis. Dec 01, 2006

Curcumin appears to be a complementary treatment option for COVID-19 patients.Dec 31, 2022

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