Curcumin

Name	AC	CK
Oxidative Stress	318	701
Inflammation	193	586
Diabetes Mellitus: Type 2	66	241
Breast Cancer	146	215
Obesity	56	199
Alzheimer's Disease	109	196
Depression	36	189
Nonalcoholic fatty liver disease (NAFLD)	31	179
Ulcerative Colitis	34	156
Osteoarthritis: Knee	20	145
Colorectal Cancer	71	133
Cancers: All	124	131
Osteoarthritis	32	129
Prostate Cancer	77	112
Colon Cancer	83	111
Lipid Peroxidation	44	111
Liver Cancer	74	111
Chemically-Induced Liver Damage	51	101
Lipopolysaccharide-Induced Toxicity	72	101
Coronavirus Infection	34	100
Lung Cancer	80	99
Cancers: Drug Resistant	77	95
Insulin Resistance	29	91
Rheumatoid Arthritis	19	89
Wound Healing	53	89
Inflammatory Bowel Diseases	39	88
C-Reactive Protein	10	87
Chronic Kidney Disease (CKD)	14	82
DNA damage	47	82
Polycystic Ovary Syndrome	13	81
Neurodegenerative Diseases	55	79
Oral Cancer	32	78
Pancreatic Cancer	39	78
Melanoma	44	75
Parkinson's Disease	49	72
Brain Inflammation	45	70
Hypertension	17	69
Endothelial Dysfunction	20	67
Colitis	30	66
Periodontitis	14	66
Oral Submucous Fibrosis	9	65
Aging	30	64
Multiple Myeloma	18	62
Skin Cancer	23	60
Chemotherapy-Induced Toxicity: Cisplatin	33	59
Cancer Metastasis	44	58
Glioblastoma	31	58
Hyperlipidemia	20	58
Liver Fibrosis	35	57
Alcohol Toxicity	23	55
Hyperglycemia	16	54
Atherosclerosis	25	53
Head and Neck Cancer	24	53
Oral Mucositis	6	52
Epilepsy	20	50
Arthritis	19	49
Spinal Cord Injuries	14	49
Gastric Cancer	36	48
Helicobacter Pylori Infection	16	48
Cardiovascular Diseases	23	46
Metabolic Syndrome X	9	46
Cervical Cancer	40	45
Muscle Damage: Exercise-Induced	8	45
Psoriasis	19	45
Depressive Disorder	5	44
Diabetic Nephropathy	17	44
Dysmenorrhea	7	43
Myocardial Infarction	14	43
Dyslipidemias	8	42
Premenstrual syndrome	6	42
Radiation Induced Illness	24	42
Tumors	22	42
Asthma	20	41
Cognitive Decline/Dysfunction	18	40
Arsenic Poisoning	13	39
Diabetic Complications	23	39
Proteinuria	7	39
Anxiety	9	38
Brain Injury: Traumatic	11	38
Fatty Liver	12	38
High Fat Diet	19	38
Brain: Oxidative Stress	11	37
Cholestasis	7	37
HIV Infections	20	37
Ovarian Cancer	34	37
Periodontal Diseases	8	37
Pesticide Toxicity	21	37
Breast Cancer: Triple Negative	25	36
Chronic Obstructive Pulmonary Disease	7	36
Metabolic Diseases	13	36
Cancers: Multi-Drug Resistant	34	34
Chemotherapy-Induced Toxicity: Doxorubicin	15	34
Diabetes Mellitus: Type 1	19	34
Glioma	24	34
Bladder Cancer	27	33
Leukemia	31	33
Thalassemia	6	33
Advanced Glycation End products (AGE)	8	32
Alcoholic Liver Disease	9	32
Chemical Weapon Agent Injury: Sulfur Mustard	4	32
Diabetic Retinopathy	11	32
Headache: Migraine	4	32
Leukoplakia	5	32
Muscle Damage	3	32
Benzo[a]pyrene-induced Toxicity	19	31
Irritable Bowel Syndrome	9	31
Multiple Sclerosis	16	31
Myocardial Ischemia	13	31
Spondylitis: Ankylosing	2	31
Squamous cell carcinoma	24	31
Diabetes: Cardiovascular Illness	12	30
Human Papillomavirus (HPV)	15	30
Liver Damage	17	30
Memory Disorders	15	30
Sepsis	14	30
Aflatoxicosis	15	28
Brain Ischemia	15	28
Liver Damage: Drug-Induced	12	28
Pulmonary Fibrosis	15	28
Testicular Injury: Chemical/Metal Induced	14	28
Aluminum Toxicity	15	27
Lung Injury: Acute	14	27
Malaria	20	27
Systemic Lupus Erythematosus	5	27
Carcinoma: Non-Small-Cell Lung	21	26
Chemotherapy and Radiation Toxicity	5	26
Stress	9	26
Uveitis	6	26
Chronic Pain	9	25
Dry Eye Syndromes	5	25
Endometriosis	14	25
High Cholesterol	9	25
Kidney Damage	13	25
Cholesterol: Oxidation	11	24
Diabetic Neuropathy	3	24
Familial Adenomatous Polyposis	4	24
Gingivitis	6	24
Infertility: Male	8	24
Postmenopausal Disorders	4	24
Aging: Brain	8	23
Cerebral Ischemia	13	23
Colitis: Ulcerative	2	23
Dental Plaque	5	23
Macular Degeneration	13	23
Oral Lichen Planus	3	23
Staphylococcus aureus infection	15	23
Cadmium Poisoning	12	22
Candidiasis	3	22
Hypercholesterolemia	7	22
Liver Steatosis	8	22
Overweight	3	22
Prostatic Hyperplasia	2	22
Stroke: Ischemic	9	22
Acetaminophen (Tylenol) Toxicity	13	21
Bisphenol Toxicity	10	21
Ischemia	12	21
Pruritus	3	21
Cholesterol: LDL/HDL ratio	2	20
Colon Polyps	6	20
Crohn's Disease	9	20
HDL: Low	2	20
Liver Cirrhosis	7	20
Postoperative Recovery	2	20
Smoldering multiple myeloma (SMM)	2	20
Chemotherapy-Induced Toxicity: Bleomycin	10	19
Cystic Fibrosis	9	19
Diabetes: Oxidative Stress	11	19
Liver Damage: Aflatoxin-Induced	10	19
Osteoporosis	13	19
Promyelocytic leukemia	19	19
Thrombosis	7	19
Brain Cancer	8	18
Cataract	11	18
Lung Damage	9	18
Neuropathic Pain	10	18
Nicotine/Tobacco Toxicity	11	18
Prediabetes	4	18
Anxiety Disorders	5	17
Coronavirus Disease (Covid-19)	8	17
Dementia	5	17
Endotoxemia	9	17
Hypoxia	12	17
Leukemia: Chronic myelogenous leukemia (CML)	7	17
Neuroblastoma	13	17
Radiation Induced Illness: Mucositis	5	17
Seizures	8	17
Stroke: Attenuation/Recovery	10	17
Chemotherapy-Induced Toxicity: Cyclophosphamide	10	16
Coronary Artery Disease	4	16
Dysbiosis	5	16
Esophageal Cancer	13	16
Gastric Ulcer	9	16
Iron Overload	7	16
Lymphoma	13	16
Pancreatitis	9	16
Triglycerides: Elevated	4	16
Allergies	12	15
Brain: Microglial Activation	12	15
Cholesterol: High	4	15
Gastrointestinal Inflammation	8	15
Muscle Atrophy	9	15
Amyotrophic lateral sclerosis (ALS)	5	14
Dejerine-Sottas Disease	3	14
Depression	3	14
Fatigue: Excercise-Induced	3	14
Glaucoma	5	14
Hearing Loss	3	14
Leukemia: Chronic Lymphocytic Leukemia (CLL)	5	14
Muscle Soreness: Exercise-Induced	3	14
Peripheral Neuropathies	3	14
Prostatitis: Chronic	3	14
Vitiligo	5	14
Acne	3	13
Adiponectin: Low Levels	3	13
Arthritis: Rheumatoid	4	13
Chemotherapy-Induced Toxicity: Tamoxifen	3	13
Diabetes: Cognitive Dysfunction	7	13
Drug Toxicity: Methotrexate	7	13
Eye Diseases	4	13
Fibrosis	3	13
Gastrointestinal polyps	3	13
Heart Failure	8	13
Hyperalgesia	6	13
Mitochondrial Dysfunction	9	13
Myocardial Fibrosis	7	13
Osteosarcoma	11	13
Plasma Cell Dyscrasias	2	13
Sarcopenia	3	13
Thyroid Diseases	3	13
Acute Myeloid Leukemia	8	12
Allergic Rhinitis	2	12
Altitude Sickness	2	12
Chemical Exposure	7	12
Chemotherapy-Induced Toxicity	8	12
Chemotherapy-Induced Toxicity: Gentamicin	6	12
Cirrhosis	2	12
Drug-Induced Toxicity	6	12
Escherichia coli Infections	10	12
Insulin: Low	2	12
Left Ventricular Dysfunction	2	12
Liver Disease	7	12
Maculopathy: Age-Related	2	12
Middle Cerebral Artery Occlusion (MCAO)	6	12
Pain	6	12
Precancerous Conditions	2	12
Prostate: PSA Doubling	3	12
Schizophrenia	3	12
Allergic Airway Diseases	6	11
Autoimmune Diseases	11	11
Brain Injury: Hippocampal Damage	7	11
Dermatitis	2	11
Diabetes	2	11
Diabetes Mellitus: Type 2: Prevention	2	11
High Fructose Diet	6	11
Immune Disorders: Low Immune Function	6	11
Kidney Damage: Chemically-Induced	6	11
Leukemia: Acute myelogenous leukemia (AML)	9	11
Migraines	2	11
Neurofibromatosis	2	11
Peptic Ulcer	2	11
Phthalate Toxicity	6	11
Prostate Cancer: Metastatic	2	11
Radiation	6	11
ALT: Elevated	1	10
Abdominal Obesity (Midsection Fat)	1	10
Biliary Dyskinesia	1	10
Brain Damage	6	10
Breast Cancer: Metastatic	8	10
Bronchial Asthma	1	10
C-Reactive Protein: Diabetes-Associated	1	10
Cardiac Hypertrophy	7	10
Chemical Weapon Agent Injury	1	10
Chemotherapy	7	10
Coronary Bypass Surgery	1	10
Dementia with Lewy bodies (DLB)	1	10
Dental Care	1	10
Depression: Postpartum	1	10
Diabetic Microangiopathy	1	10
Diarrhea	1	10
Dyspepsia	1	10
Epileptic Seizures	4	10
Fluoride Toxicity	5	10
Gallbladder Disease	1	10
Gammopathy: Monoclonal	1	10
Gram-Negative Bacterial Infections	5	10
Gulf War Syndrome	1	10
Halitosis	1	10
Hemodialysis	1	10
Hemoglobinopathies	1	10
Hot Flash	1	10
Influenza A	7	10
Insulin Disorders	1	10
Intestinal Polyps	5	10
Kidney Damage: Drug-Induced	5	10
Kidney Fibrosis	5	10
Lead Poisoning	6	10
Leukemia: B-Cell	1	10
Lichen Planus	1	10
Lichen Sclerosus	1	10
Lupus Erythematosus: Cutaneous	1	10
Maculopathy	1	10
Mastitis	1	10
Monoclonal Gammopathies	1	10
Obesity: Abdominal	1	10
Orbital Pseudotumor	1	10
Organ Transplantation: Kidney	1	10
Plasma beta amyloid protein concentrations: elevated	1	10
Plasma catalase activities: elevated	1	10
Proctitis	1	10
Proctocolitis: Ulcerative	1	10
Pseudomonas aeruginosa	8	10
Quality of Life: Poor	1	10
Respiratory Infections: Infants & Children	1	10
Respiratory Tract Infections	1	10
Salivary amylase levels: elevated	1	10
Sciatic Nerve Crush Injury	5	10
Soluble cell adhesion molecules (sCAMs): elevated	1	10
Spinal Cord Inflammation	1	10
Stomatitis: Aphthous	1	10
Stroke	7	10
T-Cell Lymphoma: Cutaneous	1	10
Ulcer: Aphthous	1	10
Urinary Tract Infections	1	10
Vaginosis: Bacterial	1	10
Vertigo	1	10
Burns	5	9
Cachexia	5	9
Cholangiocarcinoma	5	9
Gastrointestinal Cancer	6	9
Heat Stroke	5	9
Hepatic Steatosis	5	9
Nasopharyngeal Cancer	8	9
Organ Transplantation	6	9
Parasitic Diseases	5	9
Testicular Diseases	5	9
Thyroid Cancer	9	9
Antibiotic Toxicity	4	8
Cardiomyopathy	5	8
Chemotherapy-Induced Kidney Damage	4	8
Copper Toxicity	5	8
Diabetes: Kidney Function	4	8
Endometrial Cancer	6	8
Herpes Simplex Virus Type 2	4	8
Leishmaniasis	8	8
Lymphoma: B-Cell	8	8
Memory Disorders: Drug-Induced	4	8
Non-Small-Cell Lung Carcinoma	8	8
Sperm Quality: Low	4	8
Staphylococcus aureus: Methicillin-resistant (MRSA)	7	8
Acute lymphoblastic leukemia (ALL)	5	7
Cancer Stem Cells	7	7
Candida Infection	7	7
Chemotherapy-Induced Toxicity: 5-fluorouracil	4	7
Colon Cancer: Prevention	4	7
Colorectal Cancer: Prevention	4	7
Dengue	6	7
Drug-Induced Toxicity: Indomethacin	4	7
Huntington Disease	6	7
Hypersensitivity	4	7
Mesothelioma	5	7
Subarachnoid hemorrhage	4	7
Amyloidosis	3	6
Amyotrophic Lateral Sclerosis	5	6
Aneurysm: Aortic	3	6
Arteriosclerosis	4	6
Autism Spectrum Disorders	4	6
Brain Edema	3	6
Cytomegalovirus Infections	4	6
Excitotoxicity	6	6
Flukes	3	6
Fungal Infection	5	6
Immune Dysregulation: TH1/TH2 imbalance	3	6
Influenza	4	6
Intestinal Cancer	3	6
Iron Poisoning	4	6
Leptin: Elevated Levels	4	6
Liver Diseases	5	6
Memory Loss	3	6
Mycobacterium abscessus	3	6
Peripheral Nerve Diseases	3	6
Smoking	4	6
Wound Healing: Delayed	3	6
Acute Myeloid Leukemia: Stem Cell	1	5
Acute T cell Leukemias	5	5
Bacterial Vaginosis	1	5
Bone Diseases	2	5
Brain Diseases	4	5
Cholera	1	5
Chronic Myeloid Leukemia	5	5
Degenerative Disk Disease	3	5
Diabetes Mellitus: Type 1: Prevention	3	5
Dioxin Toxicity	3	5
Epstein-Barr Virus Infections	4	5
Gallstones	3	5
Gastrointestinal Infections	1	5
Glomerulosclerosis	3	5
Hepatitis C	5	5
Homocysteine: Elevated	3	5
Intestinal Permeability	3	5
Intracerebral Hemorrhage	3	5
Klebsiella Infections	3	5
Leukemia: Monocytic	3	5
Liver Cancer: Prevention	3	5
Pituitary Tumours	4	5
Pneumonia	3	5
Radiation Associated Toxicity: Cobalt-60	1	5
Retinal Diseases	4	5
Retinoblastoma	5	5
Yeast Infection: Vaginal	1	5
Acinetobacter baumannii infection	4	4
Angiostrongylus Cantonensis Infection	2	4
Anti-Malarial Drug Toxicity	2	4
Aortic Stenosis	2	4
Blood Sugar Problems	2	4
Blood-Brain-Barrier Disorders	2	4
Breast Cancer Stem Cells	4	4
Burkitt Lymphoma	3	4
Cachexia: Cancer	2	4
Candida Albicans	4	4
Charcot-Marie-Tooth Disease	2	4
Chemotherapy Induced Myelotoxicity	2	4
Chemotherapy-Induced Toxicity: Adriamycin	2	4
Demyelinating Diseases	2	4
Diabetes: Liver Disease	2	4
Diabetic Neuropathies	2	4
Drug-Induced Toxicity: Cyclosporine	2	4
Drug-Induced Toxicity: Haloperidol	2	4
Drug-Induced Toxicity: Valproic Acid (Depakote)	2	4
Encephalitis: Japanese	3	4
Encephalopathies	2	4
Enterococcus Infections	4	4
Eosinophilic Meningitis	2	4
Fever	2	4
Fibrosis: Liver	2	4
Gastritis	2	4
Giardiasis	3	4
Hepatitis B	4	4
Hepatitis: Lectin-Induced (concanavalin)	2	4
Hepatoma	3	4
Herbicide Toxicity	2	4
Hydrogen Peroxide Induced Toxicity	4	4
Hypercapnia	2	4
Hyperthyroidism	2	4
Intestinal Ischemia	2	4
Kidney Diseases	3	4
Learning disorders	2	4
Left Ventricular Hypertrophy	2	4
Leiomyoma	3	4
Leptin Resistance	2	4
Lung Inflammation	2	4
Lupus Erythematosus: Systemic	3	4
Morphine Tolerance/Dependence	2	4
Mucositis	3	4
Myelodysplastic Syndromes	2	4
Neuropathies	2	4
Oral Cancer: Prevention	3	4
Organ Transplantation: Heart	2	4
Organ Transplantation: Pancreatic Islet Cells	3	4
Ovarian Diseases	2	4
Pancreatic Cancer: Metastatic	1	4
Paraquat Toxicity	2	4
Peripheral Arterial Disease	2	4
Peripheral Nerve Damage	2	4
Polycystic Kidney Diseases	2	4
Post-Traumatic Stress Disorders (PTSD)	3	4
Prenatal Chemical Exposures	2	4
Prion Diseases	3	4
Respiratory Syncytial Virus Infections	3	4
Retinitis Pigmentosa	3	4
Rhabdomyosarcoma	3	4
Sciatica	2	4
Sickle Cell Anemia	2	4
Tendon Injury	2	4
Tobacco Toxicity	2	4
Tongue Cancer	3	4
Acrylamide-induced toxicity	2	3
Adult T-cell leukemia/lymphoma (ATL)	2	3
Air Pollution Linked Toxicity	2	3
Anaphylaxis	2	3
Animal Diseases: Infectious	1	3
Animal Diseases: Porcine Epidemic Diarrhea Virus (PEDV)	1	3
Bacterial Infections and Mycoses	2	3
Bladder Cancer: Prevention	2	3
Brain Hypoxia	2	3
Breast Cancer: Lung Metastasis	2	3
Cardiomegaly	2	3
Central Nervous System Diseases	3	3
Chemotherapy-Induced Toxicity: Mitomycin-C	2	3
Circulating Free Fatty Acids: Elevated	2	3
Corticosteroid-Induced Toxicity	3	3
Cortisol: High	2	3
Diabetes: Cataract	2	3
Diabetes: Glycation/A1C	2	3
Endothelial Damage	2	3
Fibrosarcoma	2	3
Fructose-Induced Toxicity	2	3
Gastroenteritis	2	3
Heavy Metal Toxicity	2	3
Hemangioendothelioma	1	3
Herpes Labialis	1	3

Name	AC	CK
Anti-Inflammatory Agents	683	1829
Antioxidants	666	1437
Apoptotic	580	731
Neuroprotective Agents	369	703
Antiproliferative	503	694
Tumor Necrosis Factor (TNF) Alpha Inhibitor	219	544
Hepatoprotective	189	491
NF-kappaB Inhibitor	314	471
Antineoplastic Agents	325	443
Interleukin-6 Downregulation	122	332
Hypoglycemic Agents	56	283
Chemopreventive	168	282
Hypolipidemic	59	282
Immunomodulatory	107	239
Antidepressive Agents	37	209
Renoprotective	85	208
Cardioprotective	86	186
Gastrointestinal Agents	54	178
Analgesics	33	174
Chemoprotective Agents	60	167
Anti-Apoptotic	102	164
Anti-metastatic	125	163
Enzyme Inhibitors	102	163
Interleukin-1 beta downregulation	76	155
Cell cycle arrest	130	153
Chemosensitizer	132	150
Anti-Bacterial Agents	71	144
Anticarcinogenic Agents	93	144
Chemotherapeutic	85	130
Superoxide Dismutase Up-regulation	34	129
Cyclooxygenase 2 Inhibitors	82	127
Antiviral Agents	95	124
Malondialdehyde Down-regulation	28	114
Radioprotective	39	94
Anti-Fibrotic	39	85
Nrf2 activation	47	79
MicroRNA modulator	50	75
Tumor Suppressor Protein p53 Upregulation	55	74
Insulin Sensitizers	11	65
Interleukin-10 upregulation	16	63
Matrix metalloproteinase-2 (MMP-2) inhibitor	40	57
Anti-Angiogenic	37	53
Antimicrobial	20	48
Anti-Anxiety Agents	9	47
Interleukin-8 downregulation	20	47
Matrix metalloproteinase-9 (MMP-9) inhibitor	33	46
Anticholesteremic Agents	10	42
Osteoprotective	16	41
Heme oxygenase-1 up-regulation	23	39
Gastroprotective	19	38
Genoprotective	19	38
Nitric Oxide Inhibitor	20	38
Antifungal Agents	16	36
Antihypertensive Agents	14	36
Radiosensitizer	27	34
Angiogenesis Inhibitors	27	33
Wnt/β-catenin signaling pathway modulation	22	33
Cytoprotective	19	32
Cholagogues and Choleretics	3	30
Prophylactic Agents	10	30
Anticonvulsants	15	29
Interleukin-4 downregulation	7	28
Vascular Endothelial Growth Factor A Inhibitor	20	28
Anti-Ulcer Agents	11	27
Prostaglandin PGE2 downregulation	14	26
Anti-Infective Agents	5	25
Interleukin-17 downregulation	5	25
Pancreato Protective Agents	10	25
Vascular Endothelial Growth Factor Inhibitors	14	24
SIRT1 Activator	9	23
Anti-Tumor	10	22
Bcl-2 protein down-regulation	19	22
Adiponectin upregulation	3	21
Heat Shock Protein Inducer	13	20
Matrix metalloproteinase-3 (MMP-3) inhibitor	7	19
Chondroprotective	7	18
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	7	18
Regenerative	10	18
Anti-Proliferative	15	17
Antimutagenic Agents	14	17
Antinoceceptive	9	17
Epidermal growth factor receptor (EGFR) inhibitor	15	17
Histone deacetylase inhibitor	15	17
Proteasome Inhibitors	12	17
Anti-Glycation Agents	3	16
Antimalarials	14	16
Autophagy Up-regulation	14	16
P21 Activation	7	16
Vasoprotective	5	16
Immunostimulatory	10	15
Anti-Allergic Agents	10	14
Transforming growth factor beta (TGF-β) inhibitor	9	14
Transforming growth factor beta (TGF-β) upregulation	3	14
Anti-atherogenic	3	13
Antiparasitic Agents	9	13
Immunomodulatory: Th17 downregulation	3	13
Neurogenesis	8	13
Catalase Up-Regulation	2	12
Iron Chelating Agents	2	12
Nitric Oxide Enhancer	2	12
Caspase-3 Activation	7	11
Cytotoxic	11	11
Dermatologic Agents	2	11
STAT3 Inhibitor	9	11
Antipruritics	1	10
Beta-Defensin-2 Up-Regulation	1	10
Immunosuppressive Agents	7	10
Interleukin-10 downregulation	6	10
Interleukin-22 Downregulation	1	10
Malonaldehyde (MDA) Down-Regulation	1	10
Phosphorylase Kinase Inhibitors	1	10
VEGFR3 inhibition	1	10
anti-inflammatory	1	10
Detoxifier	6	9
Oncogene Suppressor	6	9
Acetylcholinesterase Inhibitor	5	8
Angiotensin-Converting Enzyme Inhibitors	5	8
Bax/Bcl2 ratio: Increase	4	8
Cyclooxygenase Inhibitors	7	8
Fertility Agents: Male	4	8
Leishmanicidal	8	8
Lipoxygenase Inhibitors	8	8
Multidrug Resistance Gene Modulators	7	8
Wnt/β-catenin pathway down-regulation	7	8
Anti-Asthmatic Agents	4	7
Autophagy Inhibitors	5	7
Brain-derived neurotrophic factor modulator	4	7
Cardiovascular Agents	4	7
Cyclooxygenase 1 Inhibitor	7	7
Protein Kinase Inhibitors	6	7
Anti-Cachexic Agents	3	6
Neuritogenic	4	6
Telomerase Inhibitor	6	6
Vasodilator Agents	3	6
Adiponectin Down-Regulation	1	5
Anti-Platelet	4	5
Anti-Retroviral Agents	1	5
Bax/Bcl2 Ratio: Decrease	3	5
Heme oxygenase-1 inducer	4	5
Interferon Gamma Reducer	3	5
Interleukin-18 down-regulation	3	5
Interleukin-4 upregulation	3	5
Platelet Aggregation Inhibitors	3	5
Spermicidal Activity	1	5
Anti-pyretic	2	4
Antispasmodic	2	4
Cell Differentiation Inducer	3	4
Glutathione Upregulation	2	4
Interleukin-2 Downregulation	2	4
Monoaminergic	2	4
Neurorestorative	2	4
Photosensitizing Agents	3	4
Vascular Cell Adhesion Molecule-1 Inhibitor	4	4
Vascular Endothelial Growth Factor Regulator	2	4
Vitamin D Receptor (VDR) Modulator	3	4
AMP-activated protein kinase modulation	2	3
Chelating Agents	2	3
Cyclin D1 Down-Regulation	3	3
Drug synergy	2	3
Estrogen Receptor Modulators	2	3
Excitatory Amino Acid Agonists	2	3
Interleukin-5 downregulation	2	3
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	3
Paraptosis	3	3
Postaglandin PGE2 downregulation	3	3
Proliferative	2	3
AKT-mammalian target of rapamycin (mTOR) pathway inhibitor	2	2
Adenosine deaminase inhibitor	1	2
Alpha-glucosidase inhibitor	2	2
Analgesics: Non-Narcotic	1	2
Analgesics: Opioid	1	2
Androgen Antagonists	1	2
Angiogenesis Inducing Agents	1	2
Angiogenesis Modulating Agents	1	2
Anti-Androgen	1	2
Anti-Inflammatory Agents: Non-Steroidal	1	2
Anti-thrombotic	1	2
Antigiardial agents	1	2
Antioxidant Effects	2	2
Anxiolytic	1	2
Calcium Channel Blockers	2	2
Cholinesterase Inhibitors	1	2
Fibroblast growth factor 21 upregulation	1	2
Gluconeogenesis Inhibitor	2	2
Glutathione S-transferase Inhibitor	2	2
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor	2	2
HIV Protease Inhibitors	2	2
Heat Shock Protein Down-Regulation	2	2
High-mobility group box-1 (HMGB1) inhibitor	1	2
Histamine H2 Antagonists	2	2
Hypoxia-inducible factor-1 (HIF-1) inhibitor	1	2
Insulin Receptor Modulator	1	2
Insulin-Like Growth Factor Inhibition/Downregulation	2	2
Insulin-releasing	1	2
Interleukin-1 alpha downregulation	1	2
Interleukin-21 downregulation	1	2
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	1	2
Matrix Metalloproteinases Inhibitors	1	2
Metal Chelation: Copper	1	2
Muscarinic Agonists	1	2
Myorelaxant	1	2
NF-E2-Related Factor-2 (Nrf2) Modulator	2	2
Neuromodulatory	1	2
Phase II Detoxification Enzyme Inducer	1	2
Photoprotective	1	2
Prostaglandin Antagonists	1	2
Proton Pump Inhibitor	1	2
Quorum Sensing Inhibition	2	2
Redox Modulator	1	2
Remyelination	1	2
Schistosomicides	1	2
Serotonin Agonists	1	2
Survivin Down-Regulation	2	2
Thromboxane (TXB) Inhibitors	1	2
Vascular Endothelial Growth Factor C Inhibitor	1	2
Vascular smooth muscle cell (VSMC) inhibitor	2	2
Xanthine oxidase inhibitor	2	2
Akt-SREBP-1 activater	1	1
Aldose reductase inhibitor	1	1
Alpha-amylase inhibitor	1	1
Anti Inflammatory	1	1
Anti-Adipogenic	1	1
Anti-HIV Agents	1	1
Anti-Infective Agents: Urinary	1	1
Anti-fungal effects	1	1
Antibiotics: Antifungal	1	1
Antidepressive Agents: Second-Generation	1	1
Antilipolytic	1	1
Antimycobacterial	1	1
Appetite Suppresant	1	1
Calcium/calmodulin dependent protein kinase II inhibitor	1	1
Cannabinoid Receptor Antagonist/Inverse Agonist	1	1
Carbonyl Reductase 1Inhibitor	1	1
Caspase-9 Activation	1	1
Enzyme Activators	1	1
Enzyme Inhibitors: Pancreatic Lipase	1	1
Eryptotic	1	1
Expectorants	1	1
Fatty Acid Synthesis Inhibitors	1	1
Glucose transporter-1 (GLUT1) expression down-regulation	1	1
Glucose transporter-2 (GLUT2) expression down-regulation	1	1
Glucose transporter-5 (GLUT5) expression down-regulation	1	1
Glyoxalase 1 inhibitor	1	1
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Inhibitor	1	1
Hypomethylating	1	1
Hypotensive	1	1
Inhibitor of Nuclear Factor Kappa-B Kinase (IKK)	1	1
Insect Repellents	1	1
Interferon-gamma (IFN-gamma) inducer	1	1
Interleukin-12 downregulation	1	1
Interleukin-6 upregulation	1	1
Intracellular adhesion molecule-1 (ICAM-1)	1	1
Leptin Down-Regulation	1	1
Leukotriene B4 downregulation	1	1
Leukotriene C4 Downregulation	1	1
Maspin (Protease Inhibitor) Up-Regulation	1	1
Mast Cell Activation Inhibitor	1	1
Matrix Metalloproteinase-7 (MMP-7) Inhibitor	1	1
Matrix metalloproteinase-14 (MMP-14) inhibitor	1	1
Matrix metalloproteinase-16 (MMP-16) inhibitor	1	1
Matrix metalloproteinase-17 (MMP-17) inhibitor	1	1
Neuroplasticity enhancement	1	1
Nonpeptidyl Inhibitors	1	1
Osteogenic	1	1
P-glycoprotein Inhibitors	1	1
P16 Activation	1	1
PI3K-AKT inhibitor	1	1
PRL-3 Down-Regulation	1	1
Palmitoylation Inhibitors	1	1
Phosphodiesterase Inhibitors	1	1
Phospholipase D Inhibitors	1	1
Protease Inhibitors	1	1
Reactive Oxygen Species (ROS) attenuation	1	1
Receptor activator of NF-κB (RANK) gene expression	1	1
S-phase kinase associated protein 2 inhibition	1	1
STAT3-NFκB Signaling: downregulation	1	1
Secretagogue	1	1
Transient Receptor Potential Melastatin 2 Inhibition	1	1
Trypanocidal Agents	1	1
Tumor Necrosis Factor (TNF) Alpha Enhancer	1	1
apoptosis	1	1

[+]

Turmeric and curcumin are therapeutic as topical agents in cancer therapy. Feb 28, 1987

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Pubmed Data : Tumori. 1987 Feb 28;73(1):29-31. PMID: 2435036

Article Published Date : Feb 28, 1987

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Skin Cancer

[+]

Turmeric has the ability to reduce weight, decrease body fat percentage, lower systolic blood pressure, and relieve anxiety for young, obese and overweight females.Feb 20, 2020

Pubmed Data : Curr Mol Pharmacol. 2024 Jan 26. Epub 2024 Jan 26. PMID: 38284733

Article Published Date : Jan 25, 2024

Study Type : Human In Vitro

Additional Links

Substances : Berberine, Curcumin

Diseases : Systemic Lupus Erythematosus

Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory

[+]

Curcumin and citral in combination may be a useful therapeutic intervention for breast cancer.Aug 31, 2015

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Pubmed Data : Mol Med Rep. 2015 Dec 28. Epub 2015 Dec 28. PMID: 26718010

Article Published Date : Dec 27, 2015

Study Type : Human In Vitro

Additional Links

Substances : Curcumin

Diseases : Advanced Glycation End products (AGE), Endothelial Dysfunction, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Glycation Agents, Anti-Inflammatory Agents, Antioxidants

[+]

Article Published Date : Aug 29, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Curcumin, Moringa oleifera

Diseases : Epilepsy

Pharmacological Actions : Anticonvulsants

[+]

Co-delivery of docetaxel and curcumin functionalized mixed micelles for the treatment of drug-resistant breast cancer.Dec 31, 2023

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Pubmed Data : Int J Nanomedicine. 2024 ;19:8603-8620. Epub 2024 Aug 22. PMID: 39188859

Article Published Date : Dec 31, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Curcumin, Vitamin E

Diseases : Breast Cancer, Cancers: Drug Resistant

Pharmacological Actions : Apoptotic

Additional Keywords : Chemotherapeutic Synergy: Docetaxel

[+]

Co-embedding of curcumin and gold nanoparticles with ZIF-8 nanoparticles for the treatment of liver cancer and its impact on metabolomics.Aug 31, 2025

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Pubmed Data : Sichuan Da Xue Xue Bao Yi Xue Ban. 2024 Sep 20 ;55(5):1159-1165. PMID: 39507956

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Pubmed Data : Int J Pharm Compd. 2018 May-Jun;22(3):196-202. PMID: 29878887

Article Published Date : Apr 30, 2018

Study Type : Human: Case Report

Additional Links

Substances : Curcumin, Green Tea

Diseases : Human Papillomavirus (HPV)

Pharmacological Actions : Antiviral Agents

[+]

Therapeutic effects of curcumin liposomes and nanocrystals on inflammatory osteolysis.May 31, 2023

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Pubmed Data : Nutr Res Pract. 2020 Oct ;14(5):438-452. Epub 2020 Aug 6. PMID: 33029285

Article Published Date : Sep 30, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Curcumin, Flavonoids

Diseases : Neurodegenerative Diseases

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

Doxycycline and curcumin can inhibit MMP expression and activity in chemically exposed corneal cells.Dec 31, 2023

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Pubmed Data : J Ophthalmic Vis Res. 2024 ;19(3):273-283. Epub 2024 Sep 16. PMID: 39359528

[+]

A combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis.Jan 01, 2010

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Pubmed Data : Food Chem Toxicol. 2010 Jan;48(1):390-5. Epub 2009 Oct 25. PMID: 19861145

Pubmed Data : J Alzheimers Dis. 2017 Feb 7. Epub 2017 Feb 7. PMID: 28222524

Article Published Date : Feb 06, 2017

Study Type : Animal Study

Additional Links

Substances : Curcumin, Resveratrol

Diseases : Aluminum Toxicity , Brain Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

Additional Keywords : Natural Substance Synergy

Problem Substances : Aluminum Chloride

[+]

A combination strategy of thymoquinone and curcumin might be considered as a potential antidote in combating liver injury induced by acetaminophen.Mar 04, 2019

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Pubmed Data : Folia Morphol (Warsz). 2019 Mar 5. Epub 2019 Mar 5. PMID: 30835338

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Pubmed Data : Diabetol Metab Syndr. 2013 ;5(1):75. Epub 2013 Nov 26. PMID: 24279645

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Pubmed Data : Int Immunopharmacol. 2024 Dec 5 ;142(Pt A):112953. Epub 2024 Sep 2. PMID: 39226828

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Pubmed Data : Avicenna J Phytomed. 2015 Nov-Dec;5(6):576-86. PMID: 26693415

Article Published Date : Oct 31, 2015

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Ischemia, Oxidative Stress

Pharmacological Actions : Renoprotective

[+]

Advantages of Curcuma longa in preventing male infertility caused by thioacetamide.Jun 30, 2024

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Pubmed Data : Open Vet J. 2024 Jul ;14(7):1585-1595. Epub 2024 Jul 31. PMID: 39175971

Article Published Date : Jun 30, 2024

Study Type : Animal Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Chemical Exposure, Infertility: Male

Pharmacological Actions : Antioxidants, Fertility Agents: Male

Additional Keywords : Plant Extracts

[+]

An isocaloric carbohydrate restriction diet and natural AMPK activating agents induce synergistic anticancer effects.Mar 18, 2015

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Pubmed Data : Eur J Cancer Prev. 2015 Mar 19. Epub 2015 Mar 19. PMID: 25747515

Article Published Date : Mar 18, 2015

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Curr Res Food Sci. 2022 ;5:1148-1157. Epub 2022 Jul 16. PMID: 35875345

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Fatigue: Excercise-Induced

Therapeutic Actions : Exercise: Swimming

Pharmacological Actions : Antioxidants

[+]

Anti-fibrotic effects of curcumin and some of its analogues in the heart.Sep 10, 2019

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Pubmed Data : Heart Fail Rev. 2019 Sep 11. Epub 2019 Sep 11. PMID: 31512150

Article Published Date : Sep 10, 2019

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Cardiovascular Diseases, Myocardial Fibrosis

Pharmacological Actions : Anti-Fibrotic, Cardioprotective

[+]

Anti-inflammatory effect of combined tetramethylpyrazine, resveratrol and curcumin in vivo.Apr 26, 2017

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Pubmed Data : BMC Complement Altern Med. 2017 Apr 27 ;17(1):233. Epub 2017 Apr 27. PMID: 28449676

Article Published Date : Apr 26, 2017

Study Type : Animal Study

Additional Links

Substances : Curcumin, Ligustrazine, Resveratrol

Diseases : Arthritis, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Anti-inflammatory effect of different curcumin preparations on adjuvant-induced arthritis.Jan 20, 2021

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Pubmed Data : Medicina (Kaunas). 2025 Mar 17 ;61(3). Epub 2025 Mar 17. PMID: 40142326

Article Published Date : Mar 16, 2025

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Pseudomonas aeruginosa, Wound Healing

Pharmacological Actions : Anti-Bacterial Agents, Antioxidants

[+]

Anticonvulsant effect of turmeric and resveratrol in lithium/pilocarpine-induced status epilepticus.Jun 13, 2022

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Pubmed Data : IUBMB Life. 2014 Jul ;66(7):496-506. Epub 2014 Jun 27. PMID: 24975030

Article Published Date : Jun 30, 2014

Study Type : Insect Study

Additional Links

Substances : Artemisinin, Curcumin

Diseases : Brain Cancer

Pharmacological Actions : Antineoplastic Agents

Additional Keywords : Natural Substance Synergy

[+]

Astragaloside IV and curcumin alone and in combination significantly reduced mean tumor weight compared to vehicle control.Dec 31, 2016

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Pubmed Data : Anticancer Res. 2017 02 ;37(2):465-473. PMID: 28179291

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Astragaloside, Curcumin

Diseases : Liver Cancer

Pharmacological Actions : Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, MicroRNA modulator, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Natural Substance Synergy

[+]

Behavioral and morphological effects of resveratrol and curcumin in rats submitted to doxorubicin-induced cognitive impairment.Oct 31, 2021

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Pubmed Data : Res Vet Sci. 2021 Nov ;140:242-250. Epub 2021 Sep 10. PMID: 34536813

Article Published Date : Oct 31, 2021

Study Type : Animal Study

Additional Links

Substances : Curcumin, Resveratrol

Diseases : Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Chemoprotective Agents

[+]

[+]

Biomimetic Curcumin-Loaded Liposomes for the Treatment of Dry Eyes and Meibomian Gland Dysfunction.Oct 26, 2024

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Pubmed Data : J Clin Med. 2024 Oct 27 ;13(21). Epub 2024 Oct 27. PMID: 39518574

Article Published Date : Oct 26, 2024

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Dry Eye Syndromes, Meibomian gland dysfunction

[+]

Bisdemethoxycurcumin and curcumin alleviate inflammatory bowel disease.Feb 11, 2025

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Pubmed Data : J Agric Food Chem. 2025 Feb 12 ;73(6):3494-3506. Epub 2025 Jan 28. PMID: 39873626

Article Published Date : Feb 11, 2025

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin

Diseases : Inflammatory Bowel Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective, NF-kappaB Inhibitor

[+]

Black seed oil-based curcumin nanoformulations ameliorated cuprizone-induced demyelination in the mouse hippocampus.Jun 17, 2024

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Pubmed Data : Mol Neurobiol. 2024 Jun 18. Epub 2024 Jun 18. PMID: 38890237

Article Published Date : Jun 17, 2024

Study Type : Animal Study

Additional Links

Substances : Curcumin, Nigella sativa (aka Black Seed)

Diseases : Multiple Sclerosis

Pharmacological Actions : Antioxidants

[+]

Boswellic acid and curcumin have chemopreventive properties on chemically-induced oral cancer. Nov 01, 2011

Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:6462956. Epub 2020 Feb 13. PMID: 32148546

Article Published Date : Dec 31, 2019

Study Type : Animal Study

Additional Links

Substances : Curcumin, St. Johns Wort

Diseases : Burns, Wound Healing

[+]

Both curcumin and its metabolite tetrahydrocurcumin exert neuroprotection against chemically-induced neurotoxicity.Apr 01, 2008

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Pubmed Data : Inflammopharmacology. 2008 Apr;16(2):96-9. PMID: 18408903

Article Published Date : Apr 01, 2008

Study Type : Animal Study

Additional Links

Substances : Curcumin, Flavonoids, Polyphenols, Tetrahydrocurcumin

Diseases : Neurodegenerative Diseases, Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Both curcumin and resveratrol show promise as anti-cachexia agents, whereas resveratrol performed better in this study.Nov 01, 2004

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Pubmed Data : Br J Cancer. 2004 Nov 1;91(9):1742-50. PMID: 15477867

Article Published Date : Nov 01, 2004

Study Type : Animal Study

Additional Links

Substances : Curcumin, Resveratrol

Diseases : Cachexia, Muscle Atrophy

Pharmacological Actions : Enzyme Inhibitors, NF-kappaB Inhibitor, Proteasome Inhibitors

Additional Keywords : Stilbenes

[+]

[+]

Cisplatin and curcumin co-loaded nano-liposomes for the treatment of hepatocellular carcinoma.Jul 09, 2018

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Pubmed Data : Int J Pharm. 2018 Jul 10 ;545(1-2):261-273. Epub 2018 May 3. PMID: 29730175

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Pubmed Data : Int J Nanomedicine. 2020 ;15:9703-9715. Epub 2020 Dec 3. PMID: 33299312

Article Published Date : Dec 31, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Ovarian Cancer

Pharmacological Actions : Apoptotic

Additional Keywords : Chemotherapeutic Synergy: Docetaxel

[+]

Coenzyme Q10 and curcumin administration improves retinal histology by reversing the pathological changes due to chronic methanol and establish a morphologically normal retina.Mar 31, 2012

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Pubmed Data : J Med Assoc Thai. 2012 Apr ;95 Suppl 4:S76-81. PMID: 22696856

Article Published Date : Mar 31, 2012

Study Type : Animal Study

Additional Links

Substances : Coenzyme Q10, Curcumin

Diseases : Methanol Toxicity

Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

[+]

Cognitive decline prevention in offspring of Pb +2 exposed mice by maternal aerobic training and Cur/CaCO 3@Cur supplementations.Jan 31, 2021

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Pubmed Data : Ecotoxicol Environ Saf. 2021 Feb ;209:111785. Epub 2020 Dec 18. PMID: 33348254

Article Published Date : Jan 31, 2021

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Fetal Origin of Adult Disease, Prenatal Chemical Exposures

Therapeutic Actions : Exercise: Aerobic

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Plant Extracts

Problem Substances : Lead

[+]

Colon targeted curcumin microspheres laden with ascorbic acid for bioavailability enhancement.Jul 15, 2018

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Pubmed Data : J Microencapsul. 2018 Jul 16:1-28. Epub 2018 Jul 16. PMID: 30010458

Article Published Date : Jul 15, 2018

Study Type : Animal Study

Additional Links

Substances : Curcumin, Vitamin C

Diseases : Colon Cancer

Additional Keywords : Increased Bioavailability

[+]

Colon tumors in Pirc rats were significantly reduced by 3,3'-diindolylmethane and curcumin.Dec 31, 2014

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Pubmed Data : J Med Assoc Thai. 2016 Jul ;99 Suppl 4:S23-31. PMID: 29916670

Article Published Date : Jun 30, 2016

Study Type : Animal Study

Additional Links

Substances : Curcumin, Tetrahydrocurcumin

Diseases : Cervical Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Anti-Angiogenic, Apoptotic, Cyclooxygenase 2 Inhibitors

Additional Keywords : Natural Substance/Drug Synergy

[+]

Combined curcumin and luteolin synergistically inhibit colon cancer.Jun 17, 2022

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Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2010;56(1):68-71. PMID: 20354349

Cur/Se nanoparticles could increase the bioactivity of curcumin and improve cancer therapy by regulating the gut microbiota.Dec 31, 2023

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Pubmed Data : Int J Nanomedicine. 2024 ;19:13653-13669. Epub 2024 Dec 20. PMID: 39720218

Article Published Date : Dec 31, 2023

Study Type : Animal Study

Additional Links

Substances : Curcumin, Selenium

Diseases : Cervical Cancer

Pharmacological Actions : Antiproliferative , Gastrointestinal Agents

Additional Keywords : Natural Substance Synergy

[+]

Curcuma longa (curcumin) decreases in vivo cisplatin-induced ototoxicity through heme oxygenase-1 induction.May 31, 2014

Article Published Date : May 01, 2009

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Breast Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, NF-kappaB Inhibitor

Additional Keywords : Drug-Plant-Vitamin Synergies

[+]

Curcumin (a special preparation) prevents dopamine-induced toxicity in rat brain synaptosomes.Mar 30, 2015

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Pubmed Data : Int J Pharm. 2015 Mar 31. Epub 2015 Mar 31. PMID: 25839414

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Pubmed Data : Mol Cancer Ther. 2009 Apr;8(4):959-70. PMID: 19372569

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Pubmed Data : J Invest Surg. 2023 Dec ;36(1):2164813. PMID: 36603844

Article Published Date : Nov 30, 2023

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Inflammation, Liver Damage, Liver Injury: Ischemia/reperfusion

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective

[+]

Curcumin alleviates high-fat diet-induced hepatic steatosis and obesity.Apr 30, 2021

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Pubmed Data : Food Res Int. 2021 May ;143:110270. Epub 2021 Mar 9. PMID: 33992371

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Pubmed Data : Cell Signal. 2025 Oct ;134:111909. Epub 2025 May 27. PMID: 40441470

Article Published Date : Sep 30, 2025

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Damage

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Curcumin alleviates macrophage activation and lung inflammation induced by influenza virus infection.Dec 31, 2016

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Pubmed Data : J Infect Dev Ctries. 2014 Jul ;8(7):838-44. Epub 2014 Jul 14. PMID: 25022293

Article Published Date : Jun 30, 2014

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Klebsiella Infections, Klesiella Pneumonia Infection

Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory

[+]

Curcumin alters the phase II distribution of resveratrol through inhibiting efflux transporters including MRP2 and BCRP.Oct 25, 2015

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Pubmed Data : Pharm Res. 2015 Oct 26. Epub 2015 Oct 26. PMID: 26502886

Article Published Date : Oct 25, 2015

Study Type : Animal Study

Additional Links

Substances : Curcumin, Resveratrol

Additional Keywords : Increased Bioavailability, Metabolites

[+]

Click here to read the entire abstract

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Pubmed Data : Chem Biodivers. 2022 May 10. Epub 2022 May 10. PMID: 35538560

Article Published Date : May 09, 2022

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Diabetic Nephropathy

Pharmacological Actions : Renoprotective

[+]

Curcumin ameliorates white matter injury after ischemic stroke.Dec 31, 2020

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Pubmed Data : Oxid Med Cell Longev. 2021 ;2021:1552127. Epub 2021 Sep 30. PMID: 34630845

Click here to read the entire abstract

Pubmed Data : Carcinogenesis. 2000 May;21(5):921-7. PMID: 10783313

Article Published Date : May 01, 2000

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester, Curcumin

Diseases : Familial Adenomatous Polyposis, Intestinal Polyps

Pharmacological Actions : Antiproliferative

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Turmeric and curcumin are therapeutic as topical agents in cancer therapy. Feb 28, 1987

Turmeric has the ability to reduce weight, decrease body fat percentage, lower systolic blood pressure, and relieve anxiety for young, obese and overweight females.Feb 20, 2020

Turmeric root extract supplementation improves pre-frontal cortex oxygenation and blood volume in older males and females.Feb 28, 2022

Twelve-week use of curcumin complex or its combination with boswellic acid reduces pain-related symptoms in patients with osteoarthritis.Jan 08, 2018

Vitamin D3 and curcuminoids (turmeric) stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients. Jul 01, 2009

Whey protein, omega-3 fatty acids and polyphenols with electrical muscle stimulation increases muscle strength in elderly adults with limited mobility.Jun 22, 2020

Zinc and curcumin supplementation exerted a beneficial effect on several key glycemic parameters.Apr 22, 2021

ω-3 fatty acids and curcumin supplementation can be considered as a new promising approach in migraine management.May 31, 2017

Consumption of curcumin may be a plausible way to prevent quinoxaline 1,4-dioxides-mediated oxidative stress and genotoxicity in human or animals.Apr 30, 2015

Cucurbitacin B in the combination with curcumin could serve as a novel, promising approach for human hepatoma.Oct 05, 2015

Curcumin and berberine arrest maturation and activation of dendritic cells derived from Lupus erythematosus patients.Jan 25, 2024

Curcumin and citral in combination may be a useful therapeutic intervention for breast cancer.Aug 31, 2015

Curcumin as a promising candidate for the intervention of BPA-induced insulin resistance.Mar 10, 2017

Curcumin can suppress the proliferation of keratinocytes with IL-22 or without IL-22 treatment. Dec 31, 2014

Curcumin could modulate hepatocyte epithelial-mesenchymal transition implicated in treatment of liver fibrosis.Aug 23, 2015

Curcumin exhibits a spermicidal and broad-spectrum microbicidal activity against several species of bacteria and yeast involved in vaginal infections.Dec 31, 2015

Curcumin extract for prevention of type 2 diabetes.Oct 31, 2012

Curcumin inhibited proliferation and induced apoptosis in both KG-1 and U937 cells.Jun 30, 2016

Curcumin inhibited the migratory and invasive ability of A549 cells via the inhibition of adiponectin expression.Dec 31, 2014

Curcumin inhibits Aβ-induced neuronal damage and cell death involving the prevention from intracellular Ca2+ elevation mediated by the NMDA receptor.Jun 07, 2015

Curcumin may offer a viable alternative for the prevention or control of HIV replication in the female genital tract.Dec 31, 2014

Curcumin might prevent early bacterial or virus infection into the lumen of the intestine or reduce the degree of the infection by inhibiting the inflammatory response.Mar 31, 2015

Curcumin reduced Akt expression, cell proliferation, and migration in MDA-MB-231 breast cancer cells.Dec 31, 2015

Curcumin significantly inhibited the formation of advanced glycation end products (AGEs). Dec 27, 2015

Curcumin treatment causes a rapid increase in reactive oxygen species and a decrease in the mitochondrial membrane potential-events leading to apoptosis activation.Nov 30, 2014

Curcumin, piperine and taurine combination enhances the efficacy of transarterial chemoembolization therapy.Apr 30, 2024

Effects of thymoquinone and the curcumin analog EF-24 on the activity of the enzyme paraoxonase-1 in human glioblastoma cells U87MG.Nov 30, 2024

Inhibition of oncoprotein cell division cycle 20 by curcumin could be useful for the treatment of pancreatic cancer.Feb 03, 2017

Liposomes augment biological benefits of curcumin for multitargeted skin therapy.Oct 31, 2019

Radioprotective activity of curcumin-encapsulated liposomes against genotoxicity caused by gamma cobalt-60 irradiation in human blood cells.Jan 10, 2017

Rutin and baicalin could increase the binding affinity of curcumin with human serum albumin.Feb 14, 2016

The anti-cancer effect of four curcumin analogues on human glioma cells.Dec 31, 2020

Administered curcumin to a patient with laryngeal amyloidosis and smoldering myeloma and found that the patient has shown a lack of progression of his disease for a period of five years.Dec 31, 2014

Ameliorative effect of ethanolic extract of Moringa oleifera leaves in combination with curcumin against PTZ-induced kindled epilepsy.Aug 29, 2023

Co-delivery of docetaxel and curcumin functionalized mixed micelles for the treatment of drug-resistant breast cancer.Dec 31, 2023

Co-embedding of curcumin and gold nanoparticles with ZIF-8 nanoparticles for the treatment of liver cancer and its impact on metabolomics.Aug 31, 2025

Combination of curcumin and ginkgolide B inhibits cystogenesis by regulating multiple signaling pathways.Feb 28, 2021

Combination of curcumin and piperine synergistically improves pain-like behaviors in mouse models of pain.Oct 22, 2022

Curcumin activates the JAK-STAT signaling pathway to enhance the innate immune response against porcine epidemic diarrhea virus infection in vivo and in vitro.May 31, 2025

Curcumin alleviates DON-induced intestinal epithelial barrier disruption.Mar 31, 2025

Curcumin alleviates the aggressiveness of breast cancer through inhibiting cell adhesion mediated by TEAD4-fibronectin axis.Jan 31, 2025

Curcumin ameliorates cerulein‑induced chronic pancreatitis through Nrf‑2/HO‑1 signaling.Apr 30, 2025

Curcumin analog WZ26 induces ROS and cell death.Dec 30, 2023

Curcumin encapsulation in geranium oil microemulsion elevates its antibacterial, antioxidant, anti-inflammatory, and anticancer activities.Feb 05, 2024

Curcumin enhances bedaquiline's efficacy against Mycobacterium abscessus.Mar 17, 2025

Curcumin has been used to successfully treat infantile hemangioendothelioma of the liver.Aug 01, 2010

Curcumin inhibits the proliferation and migration of osteosarcoma.Apr 27, 2024

Curcumin may offer a promising therapeutic approach for improving outcomes following subarachnoid hemorrhage.Feb 28, 2025

Curcumin prevents neurodegeneration by blocking HDAC6-NLRP3 pathway-dependent neuroinflammation in Parkinson's disease.Jan 26, 2025

Curcumin relieves CFA-induced inflammatory pain.Dec 31, 2024

Curcumin-loaded gelatin nanoparticles cross the blood-brain barrier to treat ischemic stroke.Dec 31, 2023

Curcumin-QingDai combination as treatment for Crohn's disease.Dec 31, 2024

Enhanced breast cancer therapy using multifunctional lipid-coated nanoparticles combining curcumin chemotherapy and nitric oxide.Aug 04, 2024

Ethosome-based delivery of betanin and curcumin for improved anti-inflammatory efficacy.Sep 17, 2025

Evaluation of efficacy of curcumin and caffeic acid phenethyl ester in breast cancer by preclinical studies.Mar 20, 2024

Experimental study on biomimetic curcumin-mediated sonodynamic therapy of melanoma.Sep 19, 2024

Exploring the anti-inflammatory effects of curcumin encapsulated within ferritin nanocages: a comprehensive in vivo and in vitro study in Alzheimer's disease.Nov 16, 2024

Hyaluronic acid-curcumin nanoparticles for preventing the progression of experimental autoimmune uveitis.Feb 06, 2025

Inhibitory effect of curcumin on duck tembusu virus.Jul 31, 2025

Investigating a curcumin-loaded PLGA-PEG-PLGA thermo-sensitive hydrogel for the prevention of Alzheimer's disease.Apr 06, 2022

Network pharmacology and metabolomics reveal anti-ferroptotic effects of curcumin in acute kidney injury.Dec 31, 2023

Photodynamic therapy mediated by curcumin and blue light for recurrent Herpes labialis.Jan 31, 2025

Radioprotection and enhanced efficacy by curcumin-loaded chitosan nanoparticles in mitigating radiation-induced liver injury.Mar 18, 2025

Synergistic therapy with celastrol-curcumin multifunctional nanomedicine: Anti-hepatocellular carcinoma and reduced hepatotoxicity.Feb 24, 2025

The successful results obtained in this case study confirm the beneficial properties of green tea extract and curcumin against human papillomavirus.Apr 30, 2018

Therapeutic effects of curcumin liposomes and nanocrystals on inflammatory osteolysis.May 31, 2023

This paper discusses key mechanisms that lead to scar tissue formation in human skin and treatment modalities, including curcumin gel, which may result in essentially perfect skin regeneration.Aug 31, 2011

Use of curcumin in multiple myeloma patients intolerant of steroid therapy.Mar 31, 2020

[Curcumin add-on therapy for ulcerative colitis].Dec 31, 2014

BHBA, a curcumin analogue with improved Nrf2-activating and chemopreventive activities both in vitro and in vivo, could be developed into a chemoprotective pharmacological agent.Apr 18, 2015

Curcumin and hesperetin attenuate D-galactose-induced brain senescence in vitro and in vivo Sep 30, 2020

Doxycycline and curcumin can inhibit MMP expression and activity in chemically exposed corneal cells.Dec 31, 2023

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3787 Abstracts with Curcumin Research