Curcuminoids

Name	AC	CK
Oxidative Stress	279	659
Inflammation	181	556
Diabetes Mellitus: Type 2	63	223
Breast Cancer	131	192
Alzheimer's Disease	97	183
Depression	31	173
Obesity	47	136
Nonalcoholic fatty liver disease (NAFLD)	27	126
Ulcerative Colitis	25	122
Colorectal Cancer	56	117
Lipid Peroxidation	46	117
Cancers: All	104	113
Osteoarthritis	25	111
Colon Cancer	80	110
Lung Cancer	81	109
Prostate Cancer	73	109
Coronavirus Infection	35	105
Liver Cancer	68	105
Chemically-Induced Liver Damage	52	103
Lipopolysaccharide-Induced Toxicity	67	100
Glioblastoma	33	93
Osteoarthritis: Knee	14	89
Cancers: Drug Resistant	68	86
DNA damage	46	80
Rheumatoid Arthritis	18	80
Hyperglycemia	17	77
Inflammatory Bowel Diseases	35	77
Pancreatic Cancer	37	73
Wound Healing	41	73
Parkinson's Disease	46	69
C-Reactive Protein	8	67
Chronic Kidney Disease (CKD)	10	67
Neurodegenerative Diseases	45	67
Insulin Resistance	23	64
Oral Cancer	29	63
Colitis	28	62
Endothelial Dysfunction	21	61
Cancer Metastasis	44	60
Cardiovascular Diseases	25	60
Brain Inflammation	39	59
Glioma	26	57
Liver Fibrosis	35	57
Aging	22	56
Metabolic Diseases	12	55
Head and Neck Cancer	24	52
Hypertension	17	52
Multiple Myeloma	17	52
Alcohol Toxicity	20	51
Oral Mucositis	5	51
Tumors	22	50
Arthritis	16	47
Chemotherapy-Induced Toxicity: Cisplatin	32	47
Helicobacter Pylori Infection	15	47
Spinal Cord Injuries	12	47
Gastric Cancer	32	46
Melanoma	38	46
Metabolic Syndrome X	9	46
Cervical Cancer	36	45
Polycystic Ovary Syndrome	8	45
Depressive Disorder	5	44
Diabetic Nephropathy	16	44
Atherosclerosis	23	43
Chronic Pain	9	43
Diabetic Complications	21	43
Muscle Damage: Exercise-Induced	6	43
Radiation Induced Illness	24	43
Oral Submucous Fibrosis	6	42
Psoriasis	16	42
Brain Injury: Traumatic	13	41
Asthma	19	40
Periodontitis	9	40
Arsenic Poisoning	13	39
High Fat Diet	20	39
Ovarian Cancer	34	39
Proteinuria	7	39
Anxiety	8	38
Brain: Oxidative Stress	12	38
HIV Infections	21	38
Breast Cancer: Triple Negative	24	37
Cholestasis	7	37
Myocardial Infarction	14	37
Periodontal Diseases	8	37
Skin Cancer	21	37
Cancers: Multi-Drug Resistant	34	35
Cognitive Decline/Dysfunction	15	35
Stress	8	34
Bladder Cancer	27	33
Gingivitis	6	33
Leukemia	29	33
Thalassemia	6	33
Advanced Glycation End products (AGE)	8	32
Diabetes Mellitus: Type 1	18	32
Dyslipidemias	8	32
Headache: Migraine	4	32
Hyperlipidemia	16	32
Memory Disorders	14	32
Alcoholic Liver Disease	8	31
Dysmenorrhea	4	31
Leukoplakia	4	31
Multiple Sclerosis	16	31
Myocardial Ischemia	13	31
Premenstrual syndrome	4	31
Benzo[a]pyrene-induced Toxicity	18	30
Brain Ischemia	15	30
Carcinoma: Non-Small-Cell Lung	23	30
Chemical Weapon Agent Injury: Sulfur Mustard	3	30
Diabetes: Cardiovascular Illness	12	30
Human Papillomavirus (HPV)	15	30
Irritable Bowel Syndrome	8	30
Pesticide Toxicity	18	30
Squamous cell carcinoma	22	30
Lung Injury: Acute	15	29
Malaria	21	29
Fatty Liver	11	28
Iron Overload	9	28
Diabetes: Oxidative Stress	11	27
Epilepsy	16	27
Aflatoxicosis	14	26
Kidney Damage	12	26
Postmenopausal Disorders	4	26
High Cholesterol	9	25
Macular Degeneration	11	25
Pulmonary Fibrosis	13	25
Uveitis	5	25
Cerebral Ischemia	13	24
Cholesterol: Oxidation	11	24
Diabetic Neuropathy	3	24
Familial Adenomatous Polyposis	4	24
Testicular Injury: Chemical/Metal Induced	12	24
Aging: Brain	8	23
Cadmium Poisoning	12	23
Colitis: Ulcerative	2	23
Staphylococcus aureus infection	15	23
Dental Plaque	4	22
Diabetic Retinopathy	10	22
Infertility: Male	7	22
Acetaminophen (Tylenol) Toxicity	12	21
Aluminum Toxicity	12	21
Spondylitis: Ankylosing	1	21
Cholesterol: LDL/HDL ratio	2	20
Colon Polyps	6	20
Cystic Fibrosis	9	20
Dental Care	1	20
HDL: Low	2	20
Hypercholesterolemia	6	20
Ischemia	11	20
Lichen Sclerosus	1	20
Liver Cirrhosis	7	20
Liver Damage	12	20
Overweight	2	20
Postoperative Recovery	2	20
Smoldering multiple myeloma (SMM)	2	20
Bisphenol Toxicity	9	19
Promyelocytic leukemia	19	19
Allergies	13	18
Brain Cancer	8	18
Cataract	11	18
Chemotherapy-Induced Toxicity: Doxorubicin	11	18
Neuropathic Pain	10	18
Nicotine/Tobacco Toxicity	11	18
Stroke: Ischemic	7	18
Anxiety Disorders	5	17
Chemotherapy-Induced Toxicity: Cyclophosphamide	10	17
Dementia	5	17
Endotoxemia	9	17
Gastric Ulcer	8	17
Leukemia: Chronic myelogenous leukemia (CML)	7	17
Liver Damage: Aflatoxin-Induced	9	17
Neuroblastoma	13	17
Systemic Lupus Erythematosus	4	17
Chemotherapy and Radiation Toxicity	4	16
Chemotherapy-Induced Toxicity: Bleomycin	8	16
Coronary Artery Disease	4	16
Crohn's Disease	7	16
Non-Small-Cell Lung Carcinoma	10	16
Brain: Microglial Activation	12	15
Cholesterol: High	4	15
Esophageal Cancer	12	15
Fibrosis	3	15
Lymphoma	12	15
Muscle Atrophy	9	15
Osteoporosis	10	15
Radiation Induced Illness: Mucositis	4	15
Sepsis	10	15
Stroke: Attenuation/Recovery	9	15
Chronic Obstructive Pulmonary Disease	5	14
Dejerine-Sottas Disease	3	14
Depression	3	14
Dysbiosis	4	14
Endometriosis	12	14
Eye Diseases	5	14
Fatigue: Excercise-Induced	3	14
Gastrointestinal Inflammation	7	14
Glaucoma	5	14
Hypoxia	10	14
Lead Poisoning	6	14
Leukemia: Chronic Lymphocytic Leukemia (CLL)	5	14
Liver Damage: Drug-Induced	9	14
Muscle Soreness: Exercise-Induced	3	14
Peripheral Neuropathies	3	14
Prostatitis: Chronic	3	14
Acute Myeloid Leukemia	8	13
Allergic Rhinitis	3	13
Arthritis: Rheumatoid	4	13
Cardiac Hypertrophy	8	13
Chemotherapy-Induced Toxicity: Gentamicin	7	13
Diabetes: Cognitive Dysfunction	7	13
Gastrointestinal polyps	3	13
Heart Failure	8	13
Influenza	5	13
Mitochondrial Dysfunction	9	13
Myocardial Fibrosis	7	13
Pancreatitis	8	13
Phthalate Toxicity	7	13
Plasma Cell Dyscrasias	2	13
Sarcopenia	3	13
Thyroid Diseases	3	13
Brain Injury: Hippocampal Damage	7	12
Chemical Exposure	7	12
Chemotherapy-Induced Toxicity	8	12
Cirrhosis	2	12
Coronavirus Disease (Covid-19)	3	12
Diabetes Mellitus: Type 2: Prevention	2	12
Drug-Induced Toxicity	6	12
Escherichia coli Infections	10	12
High Fructose Diet	6	12
Influenza A	7	12
Insulin: Low	2	12
Left Ventricular Dysfunction	2	12
Liver Disease	7	12
Maculopathy: Age-Related	2	12
Middle Cerebral Artery Occlusion (MCAO)	6	12
Pain	6	12
Precancerous Conditions	2	12
Prostate: PSA Doubling	3	12
Prostatic Hyperplasia	2	12
Seizures	6	12
Vitiligo	3	12
Allergic Airway Diseases	6	11
Autoimmune Diseases	11	11
Diabetes	2	11
Dry Eye Syndromes	2	11
Hepatic Steatosis	6	11
Immune Disorders: Low Immune Function	6	11
Neurofibromatosis	2	11
Oral Lichen Planus	2	11
Osteosarcoma	9	11
Prostate Cancer: Metastatic	2	11
Pruritus	2	11
Schizophrenia	2	11
Stroke	7	11
Tendinopathy	2	11
Abdominal Obesity (Midsection Fat)	1	10
Biliary Dyskinesia	1	10
Brain Damage	6	10
Breast Cancer: Metastatic	8	10
Bronchial Asthma	1	10
C-Reactive Protein: Diabetes-Associated	1	10
Canker Sore	1	10
Chemical Weapon Agent Injury	1	10
Chemotherapy	7	10
Coronary Bypass Surgery	1	10
Dementia with Lewy bodies (DLB)	1	10
Diabetes: Kidney Function	5	10
Diabetic Microangiopathy	1	10
Diarrhea	1	10
Dyspepsia	1	10
Gallbladder Disease	1	10
Gammopathy: Monoclonal	1	10
Gulf War Syndrome	1	10
Halitosis	1	10
Hemodialysis	1	10
Hemoglobinopathies	1	10
Hot Flash	1	10
Hyperalgesia	5	10
Insulin Disorders	1	10
Intestinal Polyps	5	10
Kidney Fibrosis	5	10
Leukemia: B-Cell	1	10
Lichen Planus	1	10
Lupus Erythematosus: Cutaneous	1	10
Maculopathy	1	10
Mastitis	1	10
Monoclonal Gammopathies	1	10
Muscle Damage	1	10
Obesity: Abdominal	1	10
Orbital Pseudotumor	1	10
Organ Transplantation: Kidney	1	10
Peptic Ulcer	1	10
Proctitis	1	10
Proctocolitis: Ulcerative	1	10
Quality of Life: Poor	1	10
Respiratory Infections: Infants & Children	1	10
Respiratory Tract Infections	1	10
Sciatic Nerve Crush Injury	5	10
Spinal Cord Inflammation	1	10
Stomatitis: Aphthous	1	10
T-Cell Lymphoma: Cutaneous	1	10
Ulcer: Aphthous	1	10
Urinary Tract Infections	1	10
Vertigo	1	10
Cachexia	5	9
Drug Toxicity: Methotrexate	5	9
Gastrointestinal Cancer	6	9
Gram-Negative Bacterial Infections	4	9
Kidney Damage: Chemically-Induced	5	9
Nasopharyngeal Cancer	8	9
Organ Transplantation	6	9
Parasitic Diseases	5	9
Thrombosis	6	9
Traumatic Brain Injury	5	9
Antibiotic Toxicity	3	8
Burns	4	8
Chemotherapy-Induced Kidney Damage	4	8
Copper Toxicity	5	8
Epileptic Seizures	4	8
Fluoride Toxicity	4	8
Herpes Simplex Virus Type 2	4	8
Kidney Damage: Drug-Induced	4	8
Leishmaniasis	8	8
Leukemia: Acute myelogenous leukemia (AML)	6	8
Lymphoma: B-Cell	8	8
Memory Disorders: Drug-Induced	4	8
Prediabetes	3	8
Pseudomonas aeruginosa	7	8
Sperm Quality: Low	4	8
Staphylococcus aureus: Methicillin-resistant (MRSA)	7	8
Testicular Diseases	4	8
Thyroid Cancer	8	8
Acute lymphoblastic leukemia (ALL)	5	7
Amyotrophic Lateral Sclerosis	6	7
Cancer Stem Cells	7	7
Cardiomyopathy	4	7
Chemotherapy-Induced Toxicity: 5-fluorouracil	4	7
Colon Cancer: Prevention	4	7
Colorectal Cancer: Prevention	4	7
Dengue	6	7
Drug-Induced Toxicity: Indomethacin	4	7
Endometrial Cancer	5	7
Epstein-Barr Virus Infections	4	7
Hypersensitivity	4	7
Liver Steatosis	4	7
Mesothelioma	5	7
Amyloidosis	3	6
Aneurysm: Aortic	3	6
Arteriosclerosis	4	6
Autism Spectrum Disorders	4	6
Brain Edema	3	6
Candida Infection	6	6
Cholangiocarcinoma	3	6
Cytomegalovirus Infections	4	6
Diabetes: Liver Disease	3	6
Excitotoxicity	6	6
Flukes	3	6
Fungal Infection	5	6
Homocysteine: Elevated	3	6
Huntington Disease	5	6
Immune Dysregulation: TH1/TH2 imbalance	3	6
Intestinal Cancer	3	6
Iron Poisoning	4	6
Leptin: Elevated Levels	4	6
Lung Damage	3	6
Memory Loss	3	6
Peripheral Nerve Diseases	3	6
Triglycerides: Elevated	3	6
Wound Healing: Delayed	3	6
Acute Myeloid Leukemia: Stem Cell	1	5
Acute T cell Leukemias	5	5
Atopic Dermatitis	3	5
Bacterial Vaginosis	1	5
Bone Diseases	2	5
Brain Diseases	4	5
Cholera	1	5
Chronic Myeloid Leukemia	5	5
Diabetes Mellitus: Type 1: Prevention	3	5
Dioxin Toxicity	3	5
Gallstones	3	5
Gastrointestinal Infections	1	5
Glomerulosclerosis	3	5
Hepatitis C	5	5
Intestinal Permeability	3	5
Intracerebral Hemorrhage	3	5
Klebsiella Infections	3	5
Leukemia: Monocytic	3	5
Liver Cancer: Prevention	3	5
Photooxidative Stress	1	5
Pituitary Tumours	4	5
Pneumonia	3	5
Radiation Associated Toxicity: Cobalt-60	1	5
Retinal Diseases	4	5
Retinoblastoma	5	5
Smoking	3	5
Yeast Infection: Vaginal	1	5
Aging Skin	2	4
Amyotrophic lateral sclerosis (ALS)	4	4
Angiostrongylus Cantonensis Infection	2	4
Anti-Malarial Drug Toxicity	2	4
Aortic Stenosis	2	4
Blood Sugar Problems	2	4
Blood-Brain-Barrier Disorders	2	4
Breast Cancer Stem Cells	4	4
Burkitt Lymphoma	3	4
Cachexia: Cancer	2	4
Charcot-Marie-Tooth Disease	2	4
Chemotherapy Induced Myelotoxicity	2	4
Chemotherapy-Induced Toxicity: Adriamycin	2	4
Chemotherapy-Induced Toxicity: Vincristine	2	4
Demyelinating Diseases	2	4
Diabetic Neuropathies	2	4
Drug-Induced Toxicity: Cyclosporine	2	4
Drug-Induced Toxicity: Haloperidol	2	4
Ebola	2	4
Encephalitis: Japanese	3	4
Encephalopathies	2	4
Enterococcus Infections	4	4
Eosinophilic Meningitis	2	4
Eye Damage	1	4
Fever	2	4
Fibrosarcoma	2	4
Fibrosis: Liver	2	4
Food Allergies	2	4
Fructose-Induced Toxicity	2	4
Gastritis	2	4
Giardiasis	3	4
Hearing Loss	2	4
Hepatitis B	4	4
Hepatitis: Lectin-Induced (concanavalin)	2	4
Hepatoma	3	4
Herbicide Toxicity	2	4
Hydrogen Peroxide Induced Toxicity	4	4
Hypercapnia	2	4
Hyperthyroidism	2	4
Insomnia	2	4
Intestinal Ischemia	2	4
Kidney Cancer	4	4
Learning disorders	2	4
Left Ventricular Hypertrophy	2	4
Leptin Resistance	2	4
Liver Diseases	4	4
Lung Cancer: Metastatic	3	4
Lung Inflammation	2	4
Lupus Erythematosus: Systemic	3	4
Morphine Tolerance/Dependence	2	4
Myelodysplastic Syndromes	2	4
Neuropathies	2	4
Oral Cancer: Prevention	3	4
Organ Transplantation: Heart	2	4
Organ Transplantation: Pancreatic Islet Cells	3	4
Ovarian Diseases	2	4
Peripheral Arterial Disease	2	4
Polycystic Kidney Diseases	2	4
Prenatal Chemical Exposures	2	4
Prion Diseases	3	4
Radiotherapy	2	4
Respiratory Syncytial Virus Infections	3	4
Retinitis Pigmentosa	3	4
Rhabdomyosarcoma	3	4
Sickle Cell Anemia	2	4
Tobacco Toxicity	2	4
Tongue Cancer	3	4
Acinetobacter baumannii infection	3	3
Acne	2	3
Acrylamide-induced toxicity	2	3
Adiponectin: Low Levels	2	3
Adult T-cell leukemia/lymphoma (ATL)	2	3
Anaphylaxis	2	3
Bacterial Infections and Mycoses	2	3
Bladder Cancer: Prevention	2	3
Brain Hypoxia	2	3
Candida Albicans	3	3
Cardiomegaly	2	3
Chemotherapy-Induced Toxicity: Mitomycin-C	2	3
Chemotherapy-Induced Toxicity: Tamoxifen	2	3
Circulating Free Fatty Acids: Elevated	2	3
Corticosteroid-Induced Toxicity	3	3
Cortisol: High	2	3
Degenerative Disk Disease	2	3
Diabetes: Cataract	2	3
Diabetes: Glycation/A1C	2	3
Endothelial Damage	2	3
Gastroenteritis	2	3
Glioblastoma Multiforme	3	3
Heavy Metal Toxicity	2	3
Hemangioendothelioma	1	3
Herpes Labialis	1	3
Human T-Cell Lymphotrophic Virus type 1 associated disease	2	3
Hypothyroidism	2	3
Hypoxia: Brain	2	3
Immune Dysregulation: TH1 dominance	2	3
Inflammation: Neutrophil-Mediated	2	3
Insect Bites: Repellent	1	3
Kidney Diseases	2	3
Leiomyosarcoma	3	3
Leukemia: Acute promyelocytic leukemia	2	3
Leukemia: T-cell acute Lymphoblastic	3	3
Lung Cancer Stem Cell	2	3
Mitochondrial Diseases	2	3
Mucositis	2	3
Mycobacterium abscessus	2	3
NSAID-induced toxicity	2	3

Name	AC	CK
Anti-Inflammatory Agents	593	1604
Antioxidants	605	1352
Apoptotic	557	752
Antiproliferative	459	660
Neuroprotective Agents	332	645
Tumor Necrosis Factor (TNF) Alpha Inhibitor	197	482
NF-kappaB Inhibitor	303	453
Antineoplastic Agents	292	407
Hepatoprotective	172	399
Interleukin-6 Downregulation	101	258
Chemopreventive	158	254
Hypoglycemic Agents	46	229
Hypolipidemic	49	198
Renoprotective	80	197
Antidepressive Agents	33	185
Immunomodulatory	92	178
Cardioprotective	81	175
Analgesics	31	171
Cell cycle arrest	132	170
Anti-metastatic	123	165
Anticarcinogenic Agents	93	165
Enzyme Inhibitors	102	165
Chemosensitizer	129	151
Chemotherapeutic	86	138
Cyclooxygenase 2 Inhibitors	83	134
Chemoprotective Agents	56	133
Anti-Apoptotic	83	131
Antiviral Agents	91	128
Gastrointestinal Agents	33	127
Interleukin-1 beta downregulation	62	125
Malondialdehyde Down-regulation	27	121
Anti-Bacterial Agents	59	109
Superoxide Dismutase Up-regulation	26	109
Anti-Fibrotic	33	81
Nrf2 activation	46	80
Radioprotective	32	74
Tumor Suppressor Protein p53 Upregulation	53	72
MicroRNA modulator	47	71
Interleukin-10 upregulation	13	57
Matrix metalloproteinase-2 (MMP-2) inhibitor	41	57
Antimicrobial	19	56
Anti-Angiogenic	37	55
Anti-Anxiety Agents	9	49
Matrix metalloproteinase-9 (MMP-9) inhibitor	32	44
Anticholesteremic Agents	8	39
Gastroprotective	19	39
Genoprotective	19	38
Nitric Oxide Inhibitor	19	37
Radiosensitizer	28	37
Angiogenesis Inhibitors	26	36
Heme oxygenase-1 up-regulation	22	36
Interleukin-8 downregulation	18	35
Cytoprotective	19	32
Interleukin-4 downregulation	8	32
Bcl-2 protein down-regulation	23	31
Cholagogues and Choleretics	3	30
Prophylactic Agents	10	30
Antihypertensive Agents	13	29
Anti-Ulcer Agents	10	28
Vascular Endothelial Growth Factor A Inhibitor	20	28
Vascular Endothelial Growth Factor Inhibitors	16	28
Wnt/β-catenin signaling pathway modulation	19	27
Interleukin-17 downregulation	5	26
Anti-Infective Agents	5	25
Autophagy Up-regulation	16	25
Prostaglandin PGE2 downregulation	13	25
Anticonvulsants	13	24
Matrix metalloproteinase-3 (MMP-3) inhibitor	8	23
Anti-Tumor	10	22
Insulin Sensitizers	8	22
Heat Shock Protein Inducer	13	20
P21 Activation	7	20
SIRT1 Activator	7	20
Caspase-3 Activation	11	19
Anti-Allergic Agents	11	18
Antifungal Agents	16	18
Antimalarials	15	18
Pancreato Protective Agents	7	18
Regenerative	10	18
Anti-Proliferative	15	17
Antimutagenic Agents	14	17
Antinoceceptive	9	17
Epidermal growth factor receptor (EGFR) inhibitor	15	17
Immunostimulatory	10	17
Proteasome Inhibitors	12	17
Anti-Glycation Agents	3	16
Vasoprotective	4	15
Transforming growth factor beta (TGF-β) inhibitor	9	14
Anti-atherogenic	3	13
Chondroprotective	4	13
Histone deacetylase inhibitor	13	13
Antiparasitic Agents	8	12
Iron Chelating Agents	2	12
Acetylcholinesterase Inhibitor	6	11
Adiponectin upregulation	2	11
Immunomodulatory: Th17 downregulation	2	11
Neurogenesis	7	11
STAT3 Inhibitor	9	11
Dermatologic Agents	1	10
Immunosuppressive Agents	7	10
Interleukin-10 downregulation	6	10
Interleukin-22 Downregulation	1	10
Osteoprotective	7	10
Phosphorylase Kinase Inhibitors	1	10
VEGFR3 inhibition	1	10
anti-inflammatory	1	10
Cytotoxic	9	9
Oncogene Suppressor	6	9
Vasodilator Agents	6	9
Wnt/β-catenin pathway down-regulation	7	9
Angiotensin-Converting Enzyme Inhibitors	5	8
Bax/Bcl2 ratio: Increase	4	8
Cyclooxygenase Inhibitors	7	8
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	6	8
Leishmanicidal	8	8
Lipoxygenase Inhibitors	8	8
Multidrug Resistance Gene Modulators	7	8
Photoprotective	3	8
Autophagy Inhibitors	4	7
Cardiovascular Agents	4	7
Cyclooxygenase 1 Inhibitor	7	7
Detoxifier	5	7
Protein Kinase Inhibitors	6	7
Alpha-glucosidase inhibitor	3	6
Anti-Cachexic Agents	3	6
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	2	6
Neuritogenic	4	6
Telomerase Inhibitor	6	6
Adiponectin Down-Regulation	1	5
Anti-Platelet	4	5
Anti-Retroviral Agents	1	5
Bax/Bcl2 Ratio: Decrease	3	5
Caspase-9 Activation	5	5
Cyclin D1 Down-Regulation	4	5
Heme oxygenase-1 inducer	4	5
Interferon Gamma Reducer	3	5
Interleukin-18 down-regulation	3	5
Interleukin-4 upregulation	3	5
Interleukin-5 downregulation	3	5
Photosensitizing Agents	4	5
Platelet Aggregation Inhibitors	3	5
Spermicidal Activity	1	5
Anti-Adipogenic	3	4
Anti-Asthmatic Agents	2	4
Anti-pyretic	2	4
Antispasmodic	2	4
Cell Differentiation Inducer	3	4
Excitatory Amino Acid Agonists	2	4
Fertility Agents: Male	2	4
Glutathione Upregulation	2	4
Hypoxia-inducible factor-1 (HIF-1) inhibitor	2	4
Interleukin-2 Downregulation	2	4
Monoaminergic	2	4
Neurorestorative	2	4
Proton Pump Inhibitor	1	4
Vascular Cell Adhesion Molecule-1 Inhibitor	4	4
Vitamin D Receptor (VDR) Modulator	3	4
AMP-activated protein kinase modulation	2	3
Alpha-amylase inhibitor	2	3
Brain-derived neurotrophic factor modulator	2	3
Chelating Agents	2	3
Drug synergy	2	3
Estrogen Receptor Modulators	2	3
Insect Repellents	1	3
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	3
Paraptosis	3	3
Postaglandin PGE2 downregulation	3	3
AKT-mammalian target of rapamycin (mTOR) pathway inhibitor	2	2
Adenosine deaminase inhibitor	1	2
Analgesics: Non-Narcotic	1	2
Analgesics: Opioid	1	2
Androgen Antagonists	1	2
Angiogenesis Inducing Agents	1	2
Angiogenesis Modulating Agents	1	2
Anti-Androgen	1	2
Anti-Inflammatory Agents: Non-Steroidal	1	2
Anti-thrombotic	1	2
Antigiardial agents	1	2
Antioxidant Effects	2	2
Anxiolytic	1	2
Calcium Channel Blockers	2	2
Catalase Up-Regulation	1	2
Cholinesterase Inhibitors	1	2
Enzyme Inhibitors: Pancreatic Lipase	1	2
Gluconeogenesis Inhibitor	2	2
Glucose transporter-2 (GLUT2) expression down-regulation	1	2
Glucose transporter-5 (GLUT5) expression down-regulation	1	2
Glutathione S-transferase Inhibitor	2	2
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor	2	2
HIV Protease Inhibitors	2	2
Heat Shock Protein Down-Regulation	2	2
High-mobility group box-1 (HMGB1) inhibitor	1	2
Histamine H2 Antagonists	2	2
Insulin Receptor Modulator	1	2
Insulin-Like Growth Factor Inhibition/Downregulation	2	2
Insulin-releasing	1	2
Interleukin-1 alpha downregulation	1	2
Interleukin-21 downregulation	1	2
Matrix Metalloproteinases Inhibitors	1	2
Metal Chelation: Copper	1	2
Muscarinic Agonists	1	2
Myorelaxant	1	2
NF-E2-Related Factor-2 (Nrf2) Modulator	2	2
Neuromodulatory	1	2
Nitric Oxide Enhancer	1	2
Phase II Detoxification Enzyme Inducer	1	2
Prostaglandin Antagonists	1	2
Quorum Sensing Inhibition	2	2
Redox Modulator	1	2
Remyelination	1	2
Schistosomicides	1	2
Sedative effects	1	2
Serotonin Agonists	1	2
Survivin Down-Regulation	2	2
Thromboxane (TXB) Inhibitors	1	2
Vascular Endothelial Growth Factor C Inhibitor	1	2
Vascular Endothelial Growth Factor Regulator	1	2
Vascular smooth muscle cell (VSMC) inhibitor	2	2
Xanthine oxidase inhibitor	2	2
Akt-SREBP-1 activater	1	1
Aldose reductase inhibitor	1	1
Anti Inflammatory	1	1
Anti-HIV Agents	1	1
Anti-Infective Agents: Urinary	1	1
Anti-fungal effects	1	1
Antibiotics: Antifungal	1	1
Antidepressive Agents: Second-Generation	1	1
Antilipolytic	1	1
Antimycobacterial	1	1
Appetite Suppresant	1	1
Calcium/calmodulin dependent protein kinase II inhibitor	1	1
Cannabinoid Receptor Antagonist/Inverse Agonist	1	1
Carbonyl Reductase 1Inhibitor	1	1
Caspase-8 activation	1	1
Enzyme Activators	1	1
Enzyme Inhibitors: Pancreatic Amylase	1	1
Eryptotic	1	1
Expectorants	1	1
Fatty Acid Synthesis Inhibitors	1	1
Glucose transporter-1 (GLUT1) expression down-regulation	1	1
Glyoxalase 1 inhibitor	1	1
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Inhibitor	1	1
Hypomethylating	1	1
Hypotensive	1	1
Inhibitor of Nuclear Factor Kappa-B Kinase (IKK)	1	1
Interferon-gamma (IFN-gamma) inducer	1	1
Interleukin-12 downregulation	1	1
Interleukin-6 upregulation	1	1
Intracellular adhesion molecule-1 (ICAM-1)	1	1
Leptin Down-Regulation	1	1
Leukotriene B4 downregulation	1	1
Leukotriene C4 Downregulation	1	1
Maspin (Protease Inhibitor) Up-Regulation	1	1
Mast Cell Activation Inhibitor	1	1
Matrix Metalloproteinase-7 (MMP-7) Inhibitor	1	1
Matrix metalloproteinase-14 (MMP-14) inhibitor	1	1
Matrix metalloproteinase-16 (MMP-16) inhibitor	1	1
Matrix metalloproteinase-17 (MMP-17) inhibitor	1	1
Neuroplasticity enhancement	1	1
Nonpeptidyl Inhibitors	1	1
Osteogenic	1	1
P-glycoprotein Inhibitors	1	1
P16 Activation	1	1
PI3K-AKT inhibitor	1	1
PRL-3 Down-Regulation	1	1
Palmitoylation Inhibitors	1	1
Phosphodiesterase Inhibitors	1	1
Phospholipase D Inhibitors	1	1
Proliferative	1	1
Protease Inhibitors	1	1
Reactive Oxygen Species (ROS) attenuation	1	1
Receptor activator of NF-κB (RANK) gene expression	1	1
S-phase kinase associated protein 2 inhibition	1	1
STAT3-NFκB Signaling: downregulation	1	1
Secretagogue	1	1
Transient Receptor Potential Melastatin 2 Inhibition	1	1
Trypanocidal Agents	1	1
Tumor Necrosis Factor (TNF) Alpha Enhancer	1	1
apoptosis	1	1

[+]

Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults.Mar 31, 2023

Click here to read the entire abstract

Pubmed Data : Cytokine. 2023 Apr ;164:156144. Epub 2023 Feb 15. PMID: 36804260

Article Published Date : Mar 31, 2023

Study Type : Meta Analysis, Review

Additional Links

Substances : Curcumin

Diseases : C-Reactive Protein, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Curcumin and Curcuma longa extract may improve symptoms and inflammation levels in people with arthritis.Dec 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Pharmacol Res. 2017 Sep 16. Epub 2017 Sep 16. PMID: 28928074

Article Published Date : Sep 15, 2017

Study Type : Meta Analysis, Review

Additional Links

Substances : Curcumin, Curcuminoids

Diseases : Hyperglycemia

Pharmacological Actions : Hypoglycemic Agents

[+]

Curcumin supplementation has favorable effect on metabolic markers and anthropometric parameters in patients with NAFLD.Dec 31, 2019

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Pubmed Data : Am J Med Sci. 2018 10 ;356(4):350-356. PMID: 30360803

Article Published Date : Jan 09, 2018

Study Type : Meta Analysis, Review

Additional Links

Substances : Curcumin

Diseases : Ulcerative Colitis

Additional Keywords : Significant Treatment Outcome

Problem Substances : Mesalamine

[+]

Cancer stem cells as a prognostic biomarker and therapeutic target using curcumin/ piperine extract for multiple myeloma.Sep 30, 2022

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Pubmed Data : Open Rheumatol J. 2014 ;8:77-81. Epub 2014 Oct 17. PMID: 25352926

Click here to read the entire abstract

Pubmed Data : Nutrients. 2022 Sep 13 ;14(18). Epub 2022 Sep 13. PMID: 36145139

Article Published Date : Sep 12, 2022

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : C-Reactive Protein, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

[+]

A minor metabolite from Curcuma longa effective against metabolic syndrome.May 21, 2023

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[+]

Bioactive yoghurt containing curcumin and chlorogenic acid reduces inflammation in postmenopausal women.Nov 01, 2022

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Pubmed Data : Nutrients. 2022 Nov 2 ;14(21). Epub 2022 Nov 2. PMID: 36364884

Article Published Date : Nov 01, 2022

Study Type : Human Study

Additional Links

Substances : Chlorogenic Acid, Curcumin, Yoghurt

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Bioavailability Study: Piperine enhances the serum concentration, extent of absorption and bioavailability of curcumin in both rats and humans with no adverse effects.May 01, 1998

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Pubmed Data : Planta Med. 1998 May;64(4):353-6. PMID: 9619120

Article Published Date : May 01, 1998

Study Type : Human Study

Additional Links

Substances : Curcumin, Piperidines

[+]

Bioavailable turmeric extract is as effective as paracetamol in reducing pain and other symptoms of knee osteoarthritis.Jan 29, 2021

Click here to read the entire abstract

Pubmed Data : Trials. 2021 Jan 30 ;22(1):105. Epub 2021 Jan 30. PMID: 33516238

Article Published Date : Jan 29, 2021

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Natural Substances Versus Drugs, Plant Extracts

[+]

Bioflavonoid therapy with curcumin and quercetin improves cadaveric renal transplantation in humans. Dec 15, 2005

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr J. 2021 11 13 ;20(1):91. Epub 2021 Nov 13. PMID: 34774052

Article Published Date : Jan 12, 2021

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Inflammation, Overweight

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

[+]

Curcuma longa L. extract supplementation leads to an increase in IL-10 and decreased myoglobin in recreational male runners after a half-marathon race.Jun 30, 2020

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Pubmed Data : Eur J Appl Physiol. 2020 Jul ;120(7):1531-1540. Epub 2020 May 2. PMID: 32361773

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2010 Jan 18. Epub 2010 Jan 18. PMID: 20080166

Article Published Date : Jan 18, 2010

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Alcohol Toxicity , Alcoholic Liver Disease

Pharmacological Actions : Hepatoprotective

[+]

Curcumin and Boswellia serrate has beneficial effects on glycoxidation and lipid peroxidation in chronically exercising master athletes.Nov 20, 2016

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Pubmed Data : Nutrients. 2016 Nov 21 ;8(11). Epub 2016 Nov 21. PMID: 27879642

Article Published Date : Nov 20, 2016

Study Type : Human Study

Additional Links

Substances : Curcumin, Frankincense

Diseases : Advanced Glycation End products (AGE), Lipid Peroxidation, Oxidative Stress

Pharmacological Actions : Antioxidants

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Curcumin and capsaicin might represent an alternative approach to protect against vitiligo progression.Jan 19, 2010

Click here to read the entire abstract

Pubmed Data : Antioxid Redox Signal. 2010 Jan 19. Epub 2010 Jan 19. PMID: 20085492

Article Published Date : Jan 19, 2010

Study Type : Human Study

Additional Links

Substances : Capsaicin, Curcumin

Diseases : Vitiligo

[+]

Curcumin and lycopene treatment led to significant improvements in patients suffering from oral submucous fibrosis.Jul 29, 2018

[+]

Curcumin could reverse the development of depression and enhance the outcome of antidepressants treatment in major depressive disorder.Jul 31, 2015

Click here to read the entire abstract

Pubmed Data : J Clin Psychopharmacol. 2015 Aug ;35(4):406-10. PMID: 26066335

Article Published Date : Jul 31, 2015

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Depression

Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Natural Substance/Drug Synergy, Significant Treatment Outcome

Problem Substances : Antidepressants

[+]

Curcumin exhibits anti-pre-cancer activity by increasing levels of vitamins C and E, and preventing lipid peroxidation and DNA damage.Jan 01, 2010

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Pubmed Data : J Oral Sci. 2010;52(2):251-6. PMID: 20587949

Article Published Date : Jan 01, 2010

Study Type : Human Study

Additional Links

Substances : Curcumin, Vitamin C, Vitamin E

Diseases : DNA damage, Leukoplakia, Lichen Planus, Oxidative Stress, Precancerous Conditions

Pharmacological Actions : Antioxidants

[+]

Curcumin extract improves beta cell functions in obese patients with type 2 diabetes.Sep 30, 2024

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr J. 2024 Oct 1 ;23(1):119. Epub 2024 Oct 1. PMID: 39354480

Article Published Date : Sep 30, 2024

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Hypoglycemic Agents, Pancreato Protective Agents

Additional Keywords : Plant Extracts

[+]

Curcumin gel and Aloe Vera gel are effective in improving oral submucous fibrosis symptoms.Jan 31, 2021

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Pubmed Data : Int J Clin Pharmacol Ther Toxicol. 1986 Dec;24(12):651-4. PMID: 3546166

Article Published Date : Dec 01, 1986

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Inflammation, Postoperative Recovery

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Curcumin has gall-bladder emptying properties. Jan 01, 2002

Click here to read the entire abstract

Pubmed Data : Asia Pac J Clin Nutr. 2002;11(4):314-8. PMID: 12495265

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Pharm Investig. 2014 Jul ;4(3):138-41. PMID: 25126527

Article Published Date : Jun 30, 2014

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Stomatitis: Aphthous

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Antioxidants, Immunomodulatory

[+]

Curcumin has therapeutic effects in idiopathic inflammatory orbital pseudotumours.Sep 01, 2000

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2000 Sep;14(6):443-7. PMID: 10960899

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Diagn Res. 2014 Aug ;8(8):HC19-24. Epub 2014 Aug 20. PMID: 25302215

Article Published Date : Jul 31, 2014

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Bronchial Asthma

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Curcumin holds good promise in the treatment of oral submucous fibrosis in future.Apr 30, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Oral Maxillofac Pathol. 2015 May-Aug;19(2):145-152. PMID: 26604488

Article Published Date : Apr 30, 2015

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Leukoplakia

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Oral Rehabil. 2018 Jun 16. Epub 2018 Jun 16. PMID: 29908031

Article Published Date : Jun 15, 2018

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Postoperative Recovery

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents

[+]

Curcumin is safe and efficacious in treating major depressive disorder.Jul 05, 2013

[+]

Curcumin oral gel can bring about clinical improvements in patients with oral lichen planus.Mar 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Diagn Res. 2017 Apr ;11(4):ZC89-ZC93. Epub 2017 Apr 1. PMID: 28571271

Article Published Date : Mar 31, 2017

Study Type : Human Study

Additional Links

Substances : Curcuminoids

Diseases : Oral Lichen Planus

Therapeutic Actions : Integrative Medicine

[+]

Curcumin phytosome has a beneficial effect in diabetic microangiopathy. Sep 01, 2011

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Pubmed Data : Panminerva Med. 2011 Sep ;53(3 Suppl 1):43-9. PMID: 22108476

Article Published Date : Sep 01, 2011

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Diabetic Microangiopathy

[+]

[+]

Curcumin supplementation can attenuate exercise-induced oxidative stress by increasing blood antioxidant capacity.May 31, 2014

Click here to read the entire abstract

Pubmed Data : Int J Sports Med. 2014 Jun ;35(6):469-75. Epub 2013 Oct 28. PMID: 24165958

Click here to read the entire abstract

Pubmed Data : Int Urol Nephrol. 2022 Mar 26. Epub 2022 Mar 26. PMID: 35347555

Article Published Date : Mar 25, 2022

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Hemodialysis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Curcumin supplementation influences several biomarkers that may be associated with its antidepressant mechanisms of action.Dec 31, 2014

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Pubmed Data : Eur Neuropsychopharmacol. 2015 Jan ;25(1):38-50. Epub 2014 Dec 5. PMID: 25523883

Pubmed Data : Arch Pharm Res. 2024 Dec ;47(12):924-939. Epub 2024 Nov 28. PMID: 39607647

Article Published Date : Nov 30, 2024

Study Type : Human Study

Additional Links

Substances : Curcumin

Pharmacological Actions : Hypolipidemic, Renoprotective

[+]

Curcuminoids represent an effective and safe alternative treatment for OA.Oct 31, 2014

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2014 Nov ;28(11):1625-31. Epub 2014 May 22. PMID: 24853120

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Pubmed Data : Am J Epidemiol. 2006 Nov 1;164(9):898-906. Epub 2006 Jul 26. PMID: 16870699

Article Published Date : Nov 01, 2006

Study Type : Human Study

Additional Links

Substances : Curcumin, Curry Spice

Diseases : Dementia

Pharmacological Actions : Neuroprotective Agents

[+]

Dietary supplementation with curcumin reduce circulating levels of glycogen synthase kinase-3β and islet amyloid polypeptide,Apr 08, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2020 Apr 9 ;12(4). Epub 2020 Apr 9. PMID: 32283762

Effectiveness of Curcuma longa extract for the treatment of symptoms and effusion-synovitis of knee osteoarthritis.Nov 30, 2020

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Pubmed Data : Ann Intern Med. 2020 Dec 1 ;173(11):861-869. Epub 2020 Sep 15. PMID: 32926799

Click here to read the entire abstract

Pubmed Data : J Cell Physiol. 2020 Dec 28. Epub 2020 Dec 28. PMID: 33372280

Article Published Date : Dec 27, 2020

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Coronavirus Infection

Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation

[+]

Improvement of sulphur mustard-induced chronic pruritus, quality of life and antioxidant status by curcumin: results of a randomised, double-blind, placebo-controlled trial.Sep 30, 2012

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Pubmed Data : Br J Nutr. 2012 Oct ;108(7):1272-9. Epub 2011 Nov 18. PMID: 22099425

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2021 ;12:669362. Epub 2021 May 28. PMID: 34122090

Article Published Date : Dec 31, 2020

Study Type : Human Study

Additional Links

Substances : Curcumin, Piperine

Diseases : Coronavirus Infection

Additional Keywords : Morbidity, Mortality, Risk Reduction

[+]

[+]

Reduction of atherogenic risk in patients with type 2 diabetes by curcuminoid extract: a randomized controlled trial.Jan 31, 2014

Click here to read the entire abstract

Pubmed Data : J Nutr Biochem. 2014 Feb ;25(2):144-50. Epub 2013 Nov 6. PMID: 24445038

Article Published Date : Jan 31, 2014

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Abdominal Obesity (Midsection Fat), C-Reactive Protein: Diabetes-Associated, Diabetes, Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2: Prevention, HDL: Low, Inflammation, Insulin Resistance, Obesity, Obesity: Abdominal

Pharmacological Actions : Anti-atherogenic, Anti-Inflammatory Agents

[+]

Regular endurance exercise combined with daily curcumin ingestion may reduce LV afterload to a greater extent than monotherapy with either intervention alone in postmenopausal women.May 31, 2012

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Pubmed Data : Am J Hypertens. 2012 Jun ;25(6):651-6. Epub 2012 Mar 15. PMID: 22421908

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Pubmed Data : Clin Nutr. 2015 Jan 7. Epub 2015 Jan 7. PMID: 25618800

Article Published Date : Jan 06, 2015

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2016 Jun 8. Epub 2016 Jun 8. PMID: 27270872

Article Published Date : Jun 07, 2016

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective, Hypolipidemic

Additional Keywords : Significant Treatment Outcome

[+]

Short-term supplementation with curcuminoids attenuates systemic oxidative stress in patients with osteoarthritis. Feb 16, 2015

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Pubmed Data : J Diet Suppl. 2015 Feb 17. Epub 2015 Feb 17. PMID: 25688638

Targeting inflammation through diet in patients after spinal cord injury could help with depressive symptoms. Dec 31, 2014

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Pubmed Data : J Neuroinflammation. 2015 ;12(1):204. Epub 2015 Nov 6. PMID: 26545369

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Pubmed Data : J Neuropathol Exp Neurol. 2022 May 13. Epub 2022 May 13. PMID: 35556131

Click here to read the entire abstract

Pubmed Data : Adv Exp Med Biol. 2021 ;1308:1-11. PMID: 33861432

Article Published Date : Dec 31, 2020

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Hypertension, Metabolic Syndrome X

Pharmacological Actions : Vasoprotective

[+]

The effect of nanomicelle curcumin supplementation and Nigella sativa oil on the expression level of miRNA-21, miRNA-422a, and miRNA-503 gene in postmenopausal women.Oct 31, 2021

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Pubmed Data : Phytother Res. 2021 Nov ;35(11):6216-6227. Epub 2021 Sep 8. PMID: 34496087

Article Published Date : Oct 31, 2021

Study Type : Human Study

Additional Links

Substances : Curcumin, Nigella sativa (aka Black Seed)

Diseases : Osteoarthritis

Pharmacological Actions : MicroRNA modulator

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Strength Cond Res. 2020 Oct 9. Epub 2020 Oct 9. PMID: 33044367

Article Published Date : Oct 08, 2020

Study Type : Human Study

Additional Links

Substances : Curcumin, Fenugreek, Fiber

Diseases : Fatigue: Excercise-Induced

Therapeutic Actions : Exercise

[+]

This study produced additional data on curcumin as a treatment for cancer, with a high response rate and good tolerability.Jan 15, 2016

Click here to read the entire abstract

Pubmed Data : Oncology. 2016 Jan 16. Epub 2016 Jan 16. PMID: 26771576

Article Published Date : Jan 15, 2016

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Prostate Cancer, Prostate Cancer: Metastatic

Pharmacological Actions : Chemoprotective Agents, Chemotherapeutic

Additional Keywords : Drug: Docetaxel

Problem Substances : Prednisone

[+]

This study provides preliminary evidence that curcumin and maritime pine may help alleviate symptoms of Gulf War Illness.Jan 02, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Environ Res Public Health. 2021 03 3 ;18(5). Epub 2021 Mar 3. PMID: 33802272

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2019 Jun 28 ;238:111882. Epub 2019 Apr 13. PMID: 30991137

Article Published Date : Jun 27, 2019

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Asthma

Additional Keywords : Medication Reduction, Phytotherapy

[+]

Turmeric and curcumin are therapeutic as topical agents in cancer therapy. Feb 28, 1987

Click here to read the entire abstract

Pubmed Data : Tumori. 1987 Feb 28;73(1):29-31. PMID: 2435036

Article Published Date : Feb 28, 1987

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Skin Cancer

[+]

Turmeric has the ability to reduce weight, decrease body fat percentage, lower systolic blood pressure, and relieve anxiety for young, obese and overweight females.Feb 20, 2020

Pubmed Data : Curr Mol Pharmacol. 2024 Jan 26. Epub 2024 Jan 26. PMID: 38284733

Article Published Date : Jan 25, 2024

Study Type : Human In Vitro

Additional Links

Substances : Berberine, Curcumin

Diseases : Systemic Lupus Erythematosus

Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory

[+]

Curcumin and citral in combination may be a useful therapeutic intervention for breast cancer.Aug 31, 2015

Click here to read the entire abstract

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Pubmed Data : Mol Med Rep. 2015 Dec 28. Epub 2015 Dec 28. PMID: 26718010

Article Published Date : Dec 27, 2015

Study Type : Human In Vitro

Additional Links

Substances : Curcumin

Diseases : Advanced Glycation End products (AGE), Endothelial Dysfunction, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Glycation Agents, Anti-Inflammatory Agents, Antioxidants

[+]

Click here to read the entire abstract

Pubmed Data : Spectrochim Acta A Mol Biomol Spectrosc. 2016 Feb 15 ;155:88-94. Epub 2015 Nov 7. PMID: 26583522

Article Published Date : Feb 14, 2016

Study Type : Human In Vitro

Additional Links

Substances : Curcumin, Rutin

Additional Keywords : Bioavailability

[+]

Tetrahydrocurcumin exhibited significant cell growth inhibition by inducing MCF-7 cells to undergo mitochondrial apoptosis and G2/M arrest.Apr 30, 2014

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2014 May ;67:193-200. Epub 2014 Mar 1. PMID: 24593988

Article Published Date : Apr 30, 2014

Study Type : Human In Vitro

Additional Links

Substances : Curcumin: Degradiation byproducts, Tetrahydrocurcumin

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Caspase-3 Activation, Cell cycle arrest, P21 Activation

[+]

The anti-cancer effect of four curcumin analogues on human glioma cells.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Onco Targets Ther. 2021 ;14:4345-4359. Epub 2021 Aug 4. PMID: 34376999

Article Published Date : Dec 31, 2020

Study Type : Human In Vitro

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin, Curcuminoids, Demethoxycurcumin

Diseases : Glioma

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Turmeric extract and its curcuminoids provided significant protection against photooxidative damage and apoptosis retinal cells.Feb 28, 2017

Click here to read the entire abstract

Pubmed Data : J Pharm Pharmacol. 2017 Mar ;69(3):334-340. Epub 2017 Feb 3. PMID: 28155996

Article Published Date : Feb 28, 2017

Study Type : Human In Vitro

Additional Links

Substances : Curcuminoids, Turmeric

Diseases : Macular Degeneration, Photooxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Photoprotective

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Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults.Mar 31, 2023

Curcumin and Curcuma longa extract may improve symptoms and inflammation levels in people with arthritis.Dec 31, 2021

Curcumin in the treatment of inflammation and oxidative stress responses in traumatic brain injury.Dec 31, 2023

Curcumin is likely to be of benefit in mild-to-moderate COVID-19 patients.Jan 13, 2023

Curcumin supplementation significantly reduces anthropometric indices.Apr 30, 2023

The effects of curcumin plus piperine co-administration on inflammation and oxidative stress.Mar 28, 2024

These findings suggest that curcumin may be used as an adjunct therapy in individuals with oxidative stress.Nov 30, 2019

A review of the beneficial effects of antioxidants on Helicobacter pylori eradication.Nov 30, 2018

Anti-inflammatory effects of oral supplementation with curcumin.Aug 08, 2021

Curcumin administration reduces depressive symptoms in patients with major depression.Nov 26, 2015

Curcumin as an ajuvant treatment of depression: mechanisms of action and application prospects.Dec 31, 2019

Curcumin for depression: a meta-analysis.Aug 18, 2019

Curcumin is a safe, natural bioactive substance that can effectively prevent and treat oral mucositis.Dec 31, 2020

Curcumin may provide great potential effects against diabetic kidney disease. Dec 31, 2020

Curcumin or combined curcuminoids are effective in lowering the fasting blood glucose concentrations of individuals with dysglycemia.Sep 15, 2017

Curcumin supplementation has favorable effect on metabolic markers and anthropometric parameters in patients with NAFLD.Dec 31, 2019

Curcuminoids may have some beneficial effects on knee pain and quality of life in patients with knee osteoarthritis.Mar 31, 2017

Curcuminoids supplements may be a safe and effective strategy to improve pain severity.Dec 13, 2015

Effects of Curcuma as an adjunct therapy on periodontal disease.Oct 31, 2021

Efficacy and safety of adjuvant curcumin therapy in ulcerative colitisJan 24, 2022

Efficacy and safety of dietary polyphenols in rheumatoid arthritis.Dec 31, 2022

Efficacy and safety of turmeric dietary supplementation on proteinuria in CKD.Apr 30, 2022

Meta-analysis of randomized controlled trials of 4 weeks or longer suggest that curcumin may afford some protection against oxidative stress.Jan 11, 2018

Meta-analysis: curcumin down-regulates inteleukin-6. Jul 04, 2016

Potential therapeutic effects of curcumin on glycemic and lipid profile in uncomplicated type 2 diabetes.Jan 26, 2021

The effect of curcumin as an adjunct in the treatment of chronic periodontitis.Oct 31, 2021

The potential of curcumin for treating spinal cord injury.May 03, 2022

These RCTs provide scientific evidence that supports the efficacy of turmeric extract and curcumin in the treatment of arthritis.Jul 31, 2016

This meta-analysis of RCTs suggested a significant effect of curcumin in lowering circulating TNF-α concentration.Mar 25, 2016

Turmeric and curcuminiods ameliorate disorders of glycometabolism among subjects with metabolic diseases.Feb 06, 2022

Use of curcumin in achieving clinical and endoscopic remission in ulcerative colitis.Jan 09, 2018

Cancer stem cells as a prognostic biomarker and therapeutic target using curcumin/ piperine extract for multiple myeloma.Sep 30, 2022

A bioavailable form of curcumin is well-tolerated and can positively influence weight management in overweight people.Oct 31, 2015

A combination of curcumin and fennel essential oil significantly improved symptoms and quality of life in IBS patients over 30 days.May 31, 2016

A combination of hydroxytyrosol, omega-3 fatty acids and curcumin improves pain and inflammation among early stage breast cancer patients.Mar 31, 2019

A combination of Saw Palmetto, Nettle, Curcumin and Quercetin significantly improves treatment outcome of prulifloxacin in bacterial prostatitis patients. Jun 01, 2009

A complex of curcumin and phosphatidylcholine is effective in reducing the symptoms of ostearthritis.Dec 01, 2010

A curcumin extract is appropriate for the care of patients with joint problems and may also contribute to the regeneration of cartilage.Dec 31, 2013

A curcumin formula decreased the median polyp number in familial adenomatous polyposis patients. Nov 21, 2022

A daily dose of 3.6 g curcumin achieves pharmacologically efficacious levels in the colorectum with negligible distribution of curcumin outside the gut.Jan 01, 2005

A hot water extract of C. longa may help to improve systemic glucose metabolism in people with chronic low-grade inflammation.Sep 12, 2022

A minor metabolite from Curcuma longa effective against metabolic syndrome.May 21, 2023

A pilot study to examine the effects of an anti-inflammatory supplement on eicosanoid derivatives in patients with chronic kidney disease.Jul 31, 2017

A polyherbal cream application of curcumin had a HPV clearance rate of 81.3%. Dec 31, 2012

A standardized preparation of curcuminoids compares favorably with atorvastatin on endothelial dysfunction in association with reductions in inflammatory cytokines and markers of oxidative stress. Jan 01, 2008

A supplement containing huperzine A and curcumin in dementia patients and individuals with mild cognitive impairment had beneficial effects.Dec 31, 2017

A topical preparation of curcumin successfully decreased the markers of lactational mastitis such as pain, breast tension and erythema within 72 hours of administration.Aug 31, 2014

Add-on treatment with curcumin has antidepressive effects in thai patients with major depression.Dec 31, 2017

Addition of curcumin on top of the standard anti-helicobacter regimen in patients with PU is safe and improves dyspepsia symptoms.Jun 27, 2016

Addition of curcumin to mesalamine therapy was superior to placebo and mesalamine in inducing clinical and endoscopic remission in patients with mild-to-moderate active UC.Jul 31, 2015

An exclusion diet and nutraceutical therapy has significant therapeutic effects in juvenile Crohn's disease. Jun 01, 2009

Beneficial effects of curcumin supplementation were observed in decreasing disease activity scores and severity of cirrhosis in patients with cirrhosis.Feb 02, 2020

Beneficial effects on abdominal bloating with an innovative food-grade formulation of Curcuma longa and Boswellia serrata extracts in subjects with irritable bowel syndrome.Jan 17, 2022

Bioactive yoghurt containing curcumin and chlorogenic acid reduces inflammation in postmenopausal women.Nov 01, 2022

Bioavailability Study: Piperine enhances the serum concentration, extent of absorption and bioavailability of curcumin in both rats and humans with no adverse effects.May 01, 1998

Bioavailable turmeric extract is as effective as paracetamol in reducing pain and other symptoms of knee osteoarthritis.Jan 29, 2021

Bioflavonoid therapy with curcumin and quercetin improves cadaveric renal transplantation in humans. Dec 15, 2005

Bisdemethoxycurcumin loaded H-ferritin-nanocages mediate the regulation of inflammation in Alzheimer's disease.Aug 16, 2022

Black turmeric and Aloe vera in the management of oral submucous fibrosis.Nov 30, 2021

C. longa and B. serrata resin can relieve symptoms in patients with hand osteoarthritis.Nov 30, 2022

Chelidonium and turmeric root extract have a therapeutic effect on upper abdominal pain due to functional disorders of the biliary system. Aug 15, 1999

Chemopreventive synergism between green tea extract and curcumin in patients with potentially malignant oral disorders.Apr 30, 2020

Co-administration of iron and bioavailable curcumin reduces levels of systemic markers of inflammation and oxidative stress.Feb 07, 2022

Combining nano-curcumin with catechin improves COVID-19-infected patient's inflammatory conditions.Aug 31, 2023

Curcuma longa extract improves serum inflammatory markers and mental health in healthy participants who are overweight.Jan 12, 2021

Curcuma longa L. extract supplementation leads to an increase in IL-10 and decreased myoglobin in recreational male runners after a half-marathon race.Jun 30, 2020

Curcuma-based nutritional supplements and risk of age-related macular degeneration.Oct 23, 2024

Curcumin acts as an adjuvant to imatinib in decreasing the NO levels and may help in the treatment of CML patients.Aug 15, 2011

Curcumin alleviates ethanol-induced oxidative damage in liver cells. Jan 18, 2010

Curcumin and Boswellia serrate has beneficial effects on glycoxidation and lipid peroxidation in chronically exercising master athletes.Nov 20, 2016

Curcumin and capsaicin might represent an alternative approach to protect against vitiligo progression.Jan 19, 2010

Curcuminoids

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3498 Abstracts with Curcuminoids Research