Curcuminoids

Name	AC	CK
Oxidative Stress	336	783
Inflammation	206	652
Diabetes Mellitus: Type 2	78	308
Breast Cancer	154	240
Alzheimer's Disease	116	217
Obesity	63	212
Nonalcoholic fatty liver disease (NAFLD)	37	199
Depression	37	191
Ulcerative Colitis	36	167
Osteoarthritis: Knee	20	145
Osteoarthritis	33	141
Cancers: All	130	139
Colorectal Cancer	71	135
Lipopolysaccharide-Induced Toxicity	79	119
Lipid Peroxidation	46	117
Liver Cancer	78	117
Lung Cancer	88	116
Prostate Cancer	80	116
Colon Cancer	83	113
Coronavirus Infection	35	105
Chemically-Induced Liver Damage	53	104
Cancers: Drug Resistant	79	101
Hyperglycemia	20	100
Glioblastoma	37	98
Hypertension	22	97
Insulin Resistance	30	95
Rheumatoid Arthritis	20	92
Inflammatory Bowel Diseases	39	90
Wound Healing	53	89
C-Reactive Protein	10	87
Oral Cancer	33	87
Chronic Kidney Disease (CKD)	15	84
DNA damage	47	82
Neurodegenerative Diseases	55	82
Parkinson's Disease	53	81
Polycystic Ovary Syndrome	13	81
Pancreatic Cancer	40	77
Dyslipidemias	11	75
Melanoma	44	75
Brain Inflammation	46	72
Endothelial Dysfunction	22	71
Metabolic Diseases	18	70
Aging	31	68
Colitis	31	68
Periodontitis	14	66
Chemotherapy-Induced Toxicity: Cisplatin	37	65
Oral Submucous Fibrosis	9	65
Cancer Metastasis	47	63
Cardiovascular Diseases	27	62
Multiple Myeloma	18	62
Skin Cancer	25	62
Glioma	29	60
Hyperlipidemia	20	58
Liver Fibrosis	35	57
Alcohol Toxicity	23	55
Atherosclerosis	26	55
Cervical Cancer	45	55
Head and Neck Cancer	26	55
Arthritis	20	52
Oral Mucositis	6	52
Epilepsy	20	51
Gastric Cancer	37	51
Liver Damage	18	51
Spinal Cord Injuries	15	51
Tumors	22	50
Diabetic Complications	24	49
Anxiety	9	48
Helicobacter Pylori Infection	16	48
High Fat Diet	24	47
Myocardial Infarction	15	47
Diabetic Nephropathy	18	46
Metabolic Syndrome X	9	46
Psoriasis	20	46
Chronic Pain	10	45
Muscle Damage: Exercise-Induced	8	45
Depressive Disorder	5	44
Asthma	21	43
Brain Injury: Traumatic	14	43
Dysmenorrhea	7	43
Radiation Induced Illness	24	43
Cognitive Decline/Dysfunction	19	42
Ovarian Cancer	37	42
Premenstrual syndrome	6	42
Arsenic Poisoning	14	41
Breast Cancer: Triple Negative	27	41
Fatty Liver	13	40
Prediabetes	5	39
Proteinuria	7	39
Brain: Oxidative Stress	12	38
HIV Infections	21	38
Pesticide Toxicity	22	38
Cholestasis	7	37
Periodontal Diseases	8	37
Bladder Cancer	29	36
Cancers: Multi-Drug Resistant	35	36
Chronic Obstructive Pulmonary Disease	7	36
Leukemia	32	36
Stress	9	36
Chemotherapy-Induced Toxicity: Doxorubicin	15	34
Diabetes Mellitus: Type 1	19	34
Gingivitis	7	34
Memory Disorders	15	34
Oral Lichen Planus	4	33
Thalassemia	6	33
Advanced Glycation End products (AGE)	8	32
Alcoholic Liver Disease	9	32
Carcinoma: Non-Small-Cell Lung	25	32
Chemical Weapon Agent Injury: Sulfur Mustard	4	32
Diabetic Retinopathy	11	32
Headache: Migraine	4	32
Leukoplakia	5	32
Muscle Damage	3	32
Myocardial Ischemia	14	32
Squamous cell carcinoma	24	32
Benzo[a]pyrene-induced Toxicity	19	31
Irritable Bowel Syndrome	9	31
Multiple Sclerosis	16	31
Spondylitis: Ankylosing	2	31
Brain Ischemia	15	30
Diabetes: Cardiovascular Illness	12	30
Human Papillomavirus (HPV)	15	30
Sepsis	14	30
Testicular Injury: Chemical/Metal Induced	15	30
Diabetes: Oxidative Stress	12	29
Kidney Damage	14	29
Liver Damage: Drug-Induced	13	29
Lung Injury: Acute	15	29
Malaria	21	29
Aflatoxicosis	15	28
Iron Overload	9	28
Macular Degeneration	14	28
Pulmonary Fibrosis	15	28
Aluminum Toxicity	15	27
Systemic Lupus Erythematosus	5	27
Chemotherapy and Radiation Toxicity	5	26
Postmenopausal Disorders	4	26
Uveitis	6	26
Cadmium Poisoning	13	25
Dry Eye Syndromes	5	25
Endometriosis	14	25
High Cholesterol	9	25
Cerebral Ischemia	13	24
Cholesterol: Oxidation	11	24
Diabetic Neuropathy	3	24
Familial Adenomatous Polyposis	4	24
Hypercholesterolemia	8	24
Infertility: Male	8	24
Stroke: Ischemic	10	24
Acetaminophen (Tylenol) Toxicity	14	23
Aging: Brain	8	23
Colitis: Ulcerative	2	23
Dental Plaque	5	23
Ischemia	13	23
Staphylococcus aureus infection	15	23
Candidiasis	3	22
Liver Steatosis	8	22
Overweight	3	22
Bisphenol Toxicity	10	21
Pruritus	3	21
Cholesterol: LDL/HDL ratio	2	20
Colon Polyps	6	20
Crohn's Disease	9	20
Cystic Fibrosis	9	20
Dental Care	1	20
Gastric Ulcer	10	20
HDL: Low	2	20
Lichen Sclerosus	1	20
Liver Cirrhosis	7	20
Postoperative Recovery	2	20
Smoldering multiple myeloma (SMM)	2	20
Brain Cancer	9	19
Chemotherapy-Induced Toxicity: Cyclophosphamide	11	19
Chemotherapy-Induced Toxicity: Bleomycin	10	19
Liver Damage: Aflatoxin-Induced	10	19
Osteoporosis	13	19
Promyelocytic leukemia	19	19
Thrombosis	7	19
Allergies	13	18
Cataract	11	18
Lung Damage	9	18
Neuropathic Pain	10	18
Nicotine/Tobacco Toxicity	11	18
Anxiety Disorders	5	17
Coronavirus Disease (Covid-19)	8	17
Dementia	5	17
Endotoxemia	9	17
Esophageal Cancer	13	17
Hypoxia	12	17
Leukemia: Chronic myelogenous leukemia (CML)	7	17
Neuroblastoma	13	17
Non-Small-Cell Lung Carcinoma	11	17
Osteosarcoma	13	17
Radiation Induced Illness: Mucositis	5	17
Stroke: Attenuation/Recovery	10	17
Coronary Artery Disease	4	16
Dysbiosis	5	16
Lymphoma	13	16
Pancreatitis	9	16
Seizures	8	16
Brain: Microglial Activation	12	15
Cholesterol: High	4	15
Diabetes: Cognitive Dysfunction	8	15
Fibrosis	3	15
Gastrointestinal Inflammation	8	15
Mitochondrial Dysfunction	10	15
Muscle Atrophy	9	15
Altitude Sickness	3	14
Amyotrophic lateral sclerosis (ALS)	5	14
Dejerine-Sottas Disease	3	14
Depression	3	14
Eye Diseases	5	14
Fatigue: Excercise-Induced	3	14
Glaucoma	5	14
Hearing Loss	3	14
High Fructose Diet	7	14
Lead Poisoning	6	14
Leukemia: Chronic Lymphocytic Leukemia (CLL)	5	14
Muscle Soreness: Exercise-Induced	3	14
Peripheral Neuropathies	3	14
Prostatitis: Chronic	3	14
Vitiligo	5	14
Acne	3	13
Acute Myeloid Leukemia	8	13
Adiponectin: Low Levels	3	13
Allergic Rhinitis	3	13
Arthritis: Rheumatoid	4	13
Cardiac Hypertrophy	8	13
Chemotherapy-Induced Toxicity: Gentamicin	7	13
Chemotherapy-Induced Toxicity: Tamoxifen	3	13
Drug Toxicity: Methotrexate	7	13
Gastrointestinal polyps	3	13
Heart Failure	8	13
Hyperalgesia	6	13
Influenza	5	13
Kidney Damage: Chemically-Induced	7	13
Myocardial Fibrosis	7	13
Phthalate Toxicity	7	13
Plasma Cell Dyscrasias	2	13
Sarcopenia	3	13
Thyroid Diseases	3	13
Brain Injury: Hippocampal Damage	7	12
Chemical Exposure	7	12
Chemotherapy-Induced Toxicity	8	12
Cirrhosis	2	12
Diabetes Mellitus: Type 2: Prevention	2	12
Drug-Induced Toxicity	6	12
Escherichia coli Infections	10	12
Influenza A	7	12
Insulin: Low	2	12
Kidney Fibrosis	6	12
Left Ventricular Dysfunction	2	12
Liver Disease	7	12
Maculopathy: Age-Related	2	12
Middle Cerebral Artery Occlusion (MCAO)	6	12
Pain	6	12
Precancerous Conditions	2	12
Prostate: PSA Doubling	3	12
Prostatic Hyperplasia	2	12
Schizophrenia	3	12
Allergic Airway Diseases	6	11
Autoimmune Diseases	11	11
Dermatitis	2	11
Diabetes	2	11
Hepatic Steatosis	6	11
Immune Disorders: Low Immune Function	6	11
Leukemia: Acute myelogenous leukemia (AML)	9	11
Migraines	2	11
Neurofibromatosis	2	11
Peptic Ulcer	2	11
Prostate Cancer: Metastatic	2	11
Pseudomonas aeruginosa	9	11
Radiation	6	11
Stroke	7	11
Tendinopathy	2	11
Abdominal Obesity (Midsection Fat)	1	10
Antibiotic Toxicity	4	10
Biliary Dyskinesia	1	10
Brain Damage	6	10
Breast Cancer: Metastatic	8	10
Bronchial Asthma	1	10
C-Reactive Protein: Diabetes-Associated	1	10
Canker Sore	1	10
Cardiomyopathy	6	10
Chemical Weapon Agent Injury	1	10
Chemotherapy	7	10
Coronary Bypass Surgery	1	10
Dementia with Lewy bodies (DLB)	1	10
Depression: Postpartum	1	10
Diabetes: Kidney Function	5	10
Diabetic Microangiopathy	1	10
Diarrhea	1	10
Dyspepsia	1	10
Fluoride Toxicity	5	10
Gallbladder Disease	1	10
Gammopathy: Monoclonal	1	10
Gram-Negative Bacterial Infections	5	10
Gulf War Syndrome	1	10
Halitosis	1	10
Hemodialysis	1	10
Hemoglobinopathies	1	10
Hot Flash	1	10
Insulin Disorders	1	10
Intestinal Polyps	5	10
Kidney Damage: Drug-Induced	5	10
Leukemia: B-Cell	1	10
Lichen Planus	1	10
Lupus Erythematosus: Cutaneous	1	10
Maculopathy	1	10
Mastitis	1	10
Monoclonal Gammopathies	1	10
Obesity: Abdominal	1	10
Orbital Pseudotumor	1	10
Organ Transplantation: Kidney	1	10
Proctitis	1	10
Proctocolitis: Ulcerative	1	10
Quality of Life: Poor	1	10
Respiratory Infections: Infants & Children	1	10
Respiratory Tract Infections	1	10
Sciatic Nerve Crush Injury	5	10
Spinal Cord Inflammation	1	10
Stomatitis: Aphthous	1	10
T-Cell Lymphoma: Cutaneous	1	10
Ulcer: Aphthous	1	10
Urinary Tract Infections	1	10
Vaginosis: Bacterial	1	10
Vertigo	1	10
Burns	5	9
Cachexia	5	9
Cholangiocarcinoma	5	9
Gastrointestinal Cancer	6	9
Heat Stroke	5	9
Leishmaniasis	9	9
Nasopharyngeal Cancer	8	9
Organ Transplantation	6	9
Parasitic Diseases	5	9
Staphylococcus aureus: Methicillin-resistant (MRSA)	8	9
Testicular Diseases	5	9
Thyroid Cancer	9	9
Traumatic Brain Injury	5	9
Chemotherapy-Induced Kidney Damage	4	8
Copper Toxicity	5	8
Endometrial Cancer	6	8
Epileptic Seizures	4	8
Herpes Simplex Virus Type 2	4	8
Lymphoma: B-Cell	8	8
Memory Disorders: Drug-Induced	4	8
Sperm Quality: Low	4	8
Acute lymphoblastic leukemia (ALL)	5	7
Amyotrophic Lateral Sclerosis	6	7
Bone Diseases	3	7
Cancer Stem Cells	7	7
Candida Infection	7	7
Chemotherapy-Induced Toxicity: 5-fluorouracil	4	7
Colon Cancer: Prevention	4	7
Colorectal Cancer: Prevention	4	7
Dengue	6	7
Drug-Induced Toxicity: Indomethacin	4	7
Epstein-Barr Virus Infections	4	7
Huntington Disease	6	7
Hypersensitivity	4	7
Mesothelioma	5	7
Subarachnoid hemorrhage	4	7
Amyloidosis	3	6
Aneurysm: Aortic	3	6
Arteriosclerosis	4	6
Atopic Dermatitis	4	6
Autism Spectrum Disorders	4	6
Brain Edema	3	6
Cytomegalovirus Infections	4	6
Diabetes: Liver Disease	3	6
Excitotoxicity	6	6
Flukes	3	6
Fungal Infection	5	6
Homocysteine: Elevated	3	6
Immune Dysregulation: TH1/TH2 imbalance	3	6
Intestinal Cancer	3	6
Iron Poisoning	4	6
Leptin: Elevated Levels	4	6
Liver Diseases	5	6
Memory Loss	3	6
Mycobacterium abscessus	3	6
Peripheral Nerve Diseases	3	6
Smoking	4	6
Triglycerides: Elevated	3	6
Wound Healing: Delayed	3	6
Acute Myeloid Leukemia: Stem Cell	1	5
Acute T cell Leukemias	5	5
Bacterial Vaginosis	1	5
Brain Diseases	4	5
Cholera	1	5
Chronic Myeloid Leukemia	5	5
Degenerative Disk Disease	3	5
Diabetes Mellitus: Type 1: Prevention	3	5
Dioxin Toxicity	3	5
Eye Damage	2	5
Gallstones	3	5
Gastrointestinal Infections	1	5
Glomerulosclerosis	3	5
Hepatitis C	5	5
Intestinal Permeability	3	5
Intracerebral Hemorrhage	3	5
Klebsiella Infections	3	5
Leukemia: Monocytic	3	5
Liver Cancer: Prevention	3	5
Photooxidative Stress	1	5
Pituitary Tumours	4	5
Pneumonia	3	5
Radiation Associated Toxicity: Cobalt-60	1	5
Retinal Diseases	4	5
Retinoblastoma	5	5
Ultraviolet Radiation Induced Damage	3	5
Yeast Infection: Vaginal	1	5
Acinetobacter baumannii infection	4	4
Aging Skin	2	4
Angiostrongylus Cantonensis Infection	2	4
Anti-Malarial Drug Toxicity	2	4
Aortic Stenosis	2	4
Blood Sugar Problems	2	4
Blood-Brain-Barrier Disorders	2	4
Breast Cancer Stem Cells	4	4
Burkitt Lymphoma	3	4
Cachexia: Cancer	2	4
Candida Albicans	4	4
Charcot-Marie-Tooth Disease	2	4
Chemotherapy Induced Myelotoxicity	2	4
Chemotherapy-Induced Toxicity: Adriamycin	2	4
Chemotherapy-Induced Toxicity: Vincristine	2	4
Demyelinating Diseases	2	4
Diabetic Neuropathies	2	4
Drug-Induced Toxicity: Cyclosporine	2	4
Drug-Induced Toxicity: Haloperidol	2	4
Drug-Induced Toxicity: Valproic Acid (Depakote)	2	4
Ebola	2	4
Encephalitis: Japanese	3	4
Encephalopathies	2	4
Enterococcus Infections	4	4
Eosinophilic Meningitis	2	4
Fever	2	4
Fibrosarcoma	2	4
Fibrosis: Liver	2	4
Food Allergies	2	4
Fructose-Induced Toxicity	2	4
Gastritis	2	4
Giardiasis	3	4
Hepatitis B	4	4
Hepatitis: Lectin-Induced (concanavalin)	2	4
Hepatoma	3	4
Herbicide Toxicity	2	4
Hydrogen Peroxide Induced Toxicity	4	4
Hypercapnia	2	4
Hyperthyroidism	2	4
Insomnia	2	4
Intestinal Ischemia	2	4
Kidney Cancer	4	4
Kidney Diseases	3	4
Learning disorders	2	4
Left Ventricular Hypertrophy	2	4
Leiomyoma	3	4
Leptin Resistance	2	4
Lung Cancer: Metastatic	3	4
Lung Inflammation	2	4
Lupus Erythematosus: Systemic	3	4
Morphine Tolerance/Dependence	2	4
Mucositis	3	4
Myelodysplastic Syndromes	2	4
Neuropathies	2	4
Oral Cancer: Prevention	3	4
Organ Transplantation: Heart	2	4
Organ Transplantation: Pancreatic Islet Cells	3	4
Ovarian Diseases	2	4
Paraquat Toxicity	2	4
Peripheral Arterial Disease	2	4
Peripheral Nerve Damage	2	4
Polycystic Kidney Diseases	2	4
Post-Traumatic Stress Disorders (PTSD)	3	4
Prenatal Chemical Exposures	2	4
Prion Diseases	3	4
Radiotherapy	2	4
Respiratory Syncytial Virus Infections	3	4
Retinitis Pigmentosa	3	4
Rhabdomyosarcoma	3	4
Sciatica	2	4
Sickle Cell Anemia	2	4
Tendon Injury	2	4
Tobacco Toxicity	2	4
Tongue Cancer	3	4
Acrylamide-induced toxicity	2	3
Adult T-cell leukemia/lymphoma (ATL)	2	3
Air Pollution Linked Toxicity	2	3
Anaphylaxis	2	3
Animal Diseases: Infectious	1	3
Animal Diseases: Porcine Epidemic Diarrhea Virus (PEDV)	1	3
Bacterial Infections and Mycoses	2	3
Bladder Cancer: Prevention	2	3
Brain Hypoxia	2	3
Breast Cancer: Lung Metastasis	2	3
Cardiomegaly	2	3
Central Nervous System Diseases	3	3
Chemotherapy-Induced Toxicity: Mitomycin-C	2	3
Circulating Free Fatty Acids: Elevated	2	3

Name	AC	CK
Anti-Inflammatory Agents	720	1966
Antioxidants	708	1591
Apoptotic	615	820
Antiproliferative	534	766
Neuroprotective Agents	395	763
Tumor Necrosis Factor (TNF) Alpha Inhibitor	226	592
Hepatoprotective	201	542
NF-kappaB Inhibitor	324	488
Antineoplastic Agents	327	448
Interleukin-6 Downregulation	123	336
Hypoglycemic Agents	61	333
Hypolipidemic	66	323
Chemopreventive	171	290
Immunomodulatory	110	245
Renoprotective	94	228
Cardioprotective	93	213
Antidepressive Agents	38	211
Anti-metastatic	141	196
Gastrointestinal Agents	59	196
Analgesics	34	194
Anti-Apoptotic	114	190
Cell cycle arrest	140	179
Chemosensitizer	142	176
Chemoprotective Agents	66	175
Anticarcinogenic Agents	93	165
Enzyme Inhibitors	102	165
Interleukin-1 beta downregulation	76	157
Superoxide Dismutase Up-regulation	37	155
Chemotherapeutic	94	150
Anti-Bacterial Agents	73	146
Malondialdehyde Down-regulation	32	139
Cyclooxygenase 2 Inhibitors	86	138
Antiviral Agents	96	137
Radioprotective	40	96
Anti-Fibrotic	41	92
Nrf2 activation	52	90
Antihypertensive Agents	20	85
MicroRNA modulator	52	77
Tumor Suppressor Protein p53 Upregulation	57	76
Insulin Sensitizers	11	65
Anticholesteremic Agents	12	64
Matrix metalloproteinase-2 (MMP-2) inhibitor	46	64
Interleukin-10 upregulation	16	63
Anti-Anxiety Agents	10	59
Antimicrobial	21	59
Anti-Angiogenic	37	55
Matrix metalloproteinase-9 (MMP-9) inhibitor	37	51
Gastroprotective	23	48
Interleukin-8 downregulation	21	48
Heme oxygenase-1 up-regulation	26	43
Osteoprotective	17	43
Angiogenesis Inhibitors	30	40
Antifungal Agents	18	39
Genoprotective	19	38
Nitric Oxide Inhibitor	19	37
Radiosensitizer	28	37
Wnt/β-catenin signaling pathway modulation	22	33
Cytoprotective	19	32
Interleukin-4 downregulation	8	32
Anti-Ulcer Agents	12	31
Bcl-2 protein down-regulation	23	31
Cholagogues and Choleretics	3	30
Prophylactic Agents	10	30
Autophagy Up-regulation	19	28
Vascular Endothelial Growth Factor A Inhibitor	20	28
Vascular Endothelial Growth Factor Inhibitors	16	28
Anticonvulsants	15	27
Interleukin-17 downregulation	6	27
Anti-Infective Agents	5	25
Pancreato Protective Agents	10	25
Prostaglandin PGE2 downregulation	13	25
Matrix metalloproteinase-3 (MMP-3) inhibitor	8	23
SIRT1 Activator	9	23
Anti-Tumor	10	22
Adiponectin upregulation	3	21
P21 Activation	8	21
Heat Shock Protein Inducer	13	20
Antinoceceptive	10	19
Caspase-3 Activation	11	19
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	8	19
Anti-Allergic Agents	11	18
Antimalarials	15	18
Chondroprotective	7	18
Regenerative	10	18
Anti-Proliferative	15	17
Antimutagenic Agents	14	17
Epidermal growth factor receptor (EGFR) inhibitor	15	17
Histone deacetylase inhibitor	15	17
Immunostimulatory	10	17
Proteasome Inhibitors	12	17
Anti-Glycation Agents	3	16
Vasoprotective	5	16
Transforming growth factor beta (TGF-β) inhibitor	9	14
Transforming growth factor beta (TGF-β) upregulation	3	14
Anti-atherogenic	3	13
Antiparasitic Agents	9	13
Immunomodulatory: Th17 downregulation	3	13
Neurogenesis	8	13
Catalase Up-Regulation	2	12
Iron Chelating Agents	2	12
Acetylcholinesterase Inhibitor	6	11
Cytotoxic	11	11
Dermatologic Agents	2	11
STAT3 Inhibitor	9	11
Antipruritics	1	10
Beta-Defensin-2 Up-Regulation	1	10
Immunosuppressive Agents	7	10
Interleukin-10 downregulation	6	10
Interleukin-22 Downregulation	1	10
Malonaldehyde (MDA) Down-Regulation	1	10
Phosphorylase Kinase Inhibitors	1	10
Photoprotective	4	10
VEGFR3 inhibition	1	10
anti-inflammatory	1	10
Brain-derived neurotrophic factor modulator	5	9
Detoxifier	6	9
Leishmanicidal	9	9
Oncogene Suppressor	6	9
Vasodilator Agents	6	9
Wnt/β-catenin pathway down-regulation	7	9
Angiotensin-Converting Enzyme Inhibitors	5	8
Autophagy Inhibitors	5	8
Bax/Bcl2 ratio: Increase	4	8
Cyclooxygenase Inhibitors	7	8
Fertility Agents: Male	4	8
Lipoxygenase Inhibitors	8	8
Multidrug Resistance Gene Modulators	7	8
Anti-Asthmatic Agents	4	7
Cardiovascular Agents	4	7
Cyclooxygenase 1 Inhibitor	7	7
Protein Kinase Inhibitors	6	7
Alpha-glucosidase inhibitor	3	6
Anti-Cachexic Agents	3	6
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	2	6
Neuritogenic	4	6
Telomerase Inhibitor	6	6
Adiponectin Down-Regulation	1	5
Anti-Platelet	4	5
Anti-Retroviral Agents	1	5
Bax/Bcl2 Ratio: Decrease	3	5
Caspase-9 Activation	5	5
Cyclin D1 Down-Regulation	4	5
Heme oxygenase-1 inducer	4	5
Interferon Gamma Reducer	3	5
Interleukin-18 down-regulation	3	5
Interleukin-4 upregulation	3	5
Interleukin-5 downregulation	3	5
Photosensitizing Agents	4	5
Platelet Aggregation Inhibitors	3	5
Spermicidal Activity	1	5
Anti-Adipogenic	3	4
Anti-pyretic	2	4
Antispasmodic	2	4
Cell Differentiation Inducer	3	4
Excitatory Amino Acid Agonists	2	4
Glutathione Upregulation	2	4
Hypoxia-inducible factor-1 (HIF-1) inhibitor	2	4
Interleukin-2 Downregulation	2	4
Monoaminergic	2	4
Neurorestorative	2	4
Proton Pump Inhibitor	1	4
Vascular Cell Adhesion Molecule-1 Inhibitor	4	4
Vascular Endothelial Growth Factor Regulator	2	4
Vitamin D Receptor (VDR) Modulator	3	4
AMP-activated protein kinase modulation	2	3
Alpha-amylase inhibitor	2	3
Chelating Agents	2	3
Drug synergy	2	3
Estrogen Receptor Modulators	2	3
Insect Repellents	1	3
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	3
Paraptosis	3	3
Postaglandin PGE2 downregulation	3	3
Proliferative	2	3
AKT-mammalian target of rapamycin (mTOR) pathway inhibitor	2	2
Adenosine deaminase inhibitor	1	2
Analgesics: Non-Narcotic	1	2
Analgesics: Opioid	1	2
Androgen Antagonists	1	2
Angiogenesis Inducing Agents	1	2
Angiogenesis Modulating Agents	1	2
Anti-Androgen	1	2
Anti-Inflammatory Agents: Non-Steroidal	1	2
Anti-thrombotic	1	2
Antigiardial agents	1	2
Antioxidant Effects	2	2
Anxiolytic	1	2
Calcium Channel Blockers	2	2
Cholinesterase Inhibitors	1	2
Enzyme Inhibitors: Pancreatic Lipase	1	2
Fibroblast growth factor 21 upregulation	1	2
Gluconeogenesis Inhibitor	2	2
Glucose transporter-2 (GLUT2) expression down-regulation	1	2
Glucose transporter-5 (GLUT5) expression down-regulation	1	2
Glutathione S-transferase Inhibitor	2	2
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor	2	2
HIV Protease Inhibitors	2	2
Heat Shock Protein Down-Regulation	2	2
High-mobility group box-1 (HMGB1) inhibitor	1	2
Histamine H2 Antagonists	2	2
Insulin Receptor Modulator	1	2
Insulin-Like Growth Factor Inhibition/Downregulation	2	2
Insulin-releasing	1	2
Interleukin-1 alpha downregulation	1	2
Interleukin-21 downregulation	1	2
Matrix Metalloproteinases Inhibitors	1	2
Metal Chelation: Copper	1	2
Muscarinic Agonists	1	2
Myorelaxant	1	2
NF-E2-Related Factor-2 (Nrf2) Modulator	2	2
Neuromodulatory	1	2
Nitric Oxide Enhancer	1	2
Phase II Detoxification Enzyme Inducer	1	2
Prostaglandin Antagonists	1	2
Quorum Sensing Inhibition	2	2
Redox Modulator	1	2
Remyelination	1	2
Schistosomicides	1	2
Sedative effects	1	2
Serotonin Agonists	1	2
Survivin Down-Regulation	2	2
Thromboxane (TXB) Inhibitors	1	2
Vascular Endothelial Growth Factor C Inhibitor	1	2
Vascular smooth muscle cell (VSMC) inhibitor	2	2
Xanthine oxidase inhibitor	2	2
Akt-SREBP-1 activater	1	1
Aldose reductase inhibitor	1	1
Anti Inflammatory	1	1
Anti-HIV Agents	1	1
Anti-Infective Agents: Urinary	1	1
Anti-fungal effects	1	1
Antibiotics: Antifungal	1	1
Antidepressive Agents: Second-Generation	1	1
Antilipolytic	1	1
Antimycobacterial	1	1
Appetite Suppresant	1	1
Calcium/calmodulin dependent protein kinase II inhibitor	1	1
Cannabinoid Receptor Antagonist/Inverse Agonist	1	1
Carbonyl Reductase 1Inhibitor	1	1
Caspase-8 activation	1	1
Enzyme Activators	1	1
Enzyme Inhibitors: Pancreatic Amylase	1	1
Eryptotic	1	1
Expectorants	1	1
Fatty Acid Synthesis Inhibitors	1	1
Glucose transporter-1 (GLUT1) expression down-regulation	1	1
Glyoxalase 1 inhibitor	1	1
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Inhibitor	1	1
Hypomethylating	1	1
Hypotensive	1	1
Inhibitor of Nuclear Factor Kappa-B Kinase (IKK)	1	1
Interferon-gamma (IFN-gamma) inducer	1	1
Interleukin-12 downregulation	1	1
Interleukin-6 upregulation	1	1
Intracellular adhesion molecule-1 (ICAM-1)	1	1
Leptin Down-Regulation	1	1
Leukotriene B4 downregulation	1	1
Leukotriene C4 Downregulation	1	1
Maspin (Protease Inhibitor) Up-Regulation	1	1
Mast Cell Activation Inhibitor	1	1
Matrix Metalloproteinase-7 (MMP-7) Inhibitor	1	1
Matrix metalloproteinase-14 (MMP-14) inhibitor	1	1
Matrix metalloproteinase-16 (MMP-16) inhibitor	1	1
Matrix metalloproteinase-17 (MMP-17) inhibitor	1	1
Neuroplasticity enhancement	1	1
Nonpeptidyl Inhibitors	1	1
Osteogenic	1	1
P-glycoprotein Inhibitors	1	1
P16 Activation	1	1
PI3K-AKT inhibitor	1	1
PRL-3 Down-Regulation	1	1
Palmitoylation Inhibitors	1	1
Phosphodiesterase Inhibitors	1	1
Phospholipase D Inhibitors	1	1
Protease Inhibitors	1	1
Reactive Oxygen Species (ROS) attenuation	1	1
Receptor activator of NF-κB (RANK) gene expression	1	1
S-phase kinase associated protein 2 inhibition	1	1
STAT3-NFκB Signaling: downregulation	1	1
Secretagogue	1	1
Transient Receptor Potential Melastatin 2 Inhibition	1	1
Trypanocidal Agents	1	1
Tumor Necrosis Factor (TNF) Alpha Enhancer	1	1
apoptosis	1	1

[+]

Antihypertensive effects of curcumin/turmeric supplementation in prediabetes and diabetes.Dec 31, 2025

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PeerJ. 2024 ;12:e18492. Epub 2024 Nov 15. PMID: 39559334

Article Published Date : Dec 31, 2023

Study Type : Meta Analysis, Review

Additional Links

Substances : Curcumin

Diseases : Oral Cancer, Oral Lichen Planus

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomedicine (Taipei). 2019 Dec ;9(4):23. Epub 2019 Nov 14. PMID: 31724938

Article Published Date : Nov 30, 2019

Study Type : Meta Analysis

Additional Links

Substances : Curcumin

Diseases : Brain: Oxidative Stress

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation

[+]

A review of the beneficial effects of antioxidants on Helicobacter pylori eradication.Nov 30, 2018

Click here to read the entire abstract

Pubmed Data : Helicobacter. 2018 Dec ;23(6):e12535. Epub 2018 Sep 6. PMID: 30191635

Click here to read the entire abstract

Pubmed Data : Pharmacol Res. 2017 Sep 16. Epub 2017 Sep 16. PMID: 28928074

Article Published Date : Sep 15, 2017

Study Type : Meta Analysis, Review

Additional Links

Substances : Curcumin, Curcuminoids

Diseases : Hyperglycemia

Pharmacological Actions : Hypoglycemic Agents

[+]

Curcumin supplementation has favorable effect on metabolic markers and anthropometric parameters in patients with NAFLD.Dec 31, 2019

Click here to read the entire abstract

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Pubmed Data : Iran J Kidney Dis. 2022 May ;16(3):153-161. PMID: 35714209

Article Published Date : Apr 30, 2022

Study Type : Meta Analysis

Additional Links

Substances : Curcumin

Diseases : Chronic Kidney Disease (CKD), Proteinuria

Pharmacological Actions : Renoprotective

[+]

Impact of exercise intervention with or without curcumin supplementation on body fat composition, glucose, and lipid metabolism in obese adults.Feb 28, 2025

Click here to read the entire abstract

Pubmed Data : Lipids. 2025 Mar ;60(2):65-75. Epub 2024 Nov 7. PMID: 39508270

Article Published Date : Feb 28, 2025

Study Type : Meta Analysis

Additional Links

Substances : Curcumin

Diseases : Obesity

Therapeutic Actions : Exercise

Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic

Additional Keywords : Anti-Obesity Agents

[+]

Influence of phytosomal curcumin on anthropometric indices for nonalcoholic fatty liver disease.Dec 26, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Medicine (Baltimore). 2024 Dec 27 ;103(52):e40538. PMID: 39969338

Article Published Date : Dec 26, 2024

Study Type : Meta Analysis

Additional Links

Substances : Curcumin

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

Meta-analysis of randomized controlled trials of 4 weeks or longer suggest that curcumin may afford some protection against oxidative stress.Jan 11, 2018

Click here to read the entire abstract

Pubmed Data : Nutr Res. 2018 12 ;60:1-12. Epub 2018 Sep 4. PMID: 30527253

Article Published Date : Jan 11, 2018

Study Type : Meta Analysis

Additional Links

Substances : Curcumin

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation

[+]

Click here to read the entire abstract

Pubmed Data : Am J Med Sci. 2018 10 ;356(4):350-356. PMID: 30360803

Article Published Date : Jan 09, 2018

Study Type : Meta Analysis, Review

Additional Links

Substances : Curcumin

Diseases : Ulcerative Colitis

Additional Keywords : Significant Treatment Outcome

Problem Substances : Mesalamine

[+]

Cancer stem cells as a prognostic biomarker and therapeutic target using curcumin/ piperine extract for multiple myeloma.Sep 30, 2022

Click here to read the entire abstract

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Pubmed Data : Open Rheumatol J. 2014 ;8:77-81. Epub 2014 Oct 17. PMID: 25352926

Click here to read the entire abstract

Pubmed Data : Nutrients. 2022 Sep 13 ;14(18). Epub 2022 Sep 13. PMID: 36145139

Article Published Date : Sep 12, 2022

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : C-Reactive Protein, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

[+]

A minor metabolite from Curcuma longa effective against metabolic syndrome.May 21, 2023

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Pubmed Data : Nutrients. 2022 Jan 18 ;14(3). Epub 2022 Jan 18. PMID: 35276778

Article Published Date : Jan 17, 2022

Study Type : Human Study

Additional Links

Substances : Curcumin, Frankincense

Diseases : Dysbiosis, Irritable Bowel Syndrome

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

[+]

Bioactive yoghurt containing curcumin and chlorogenic acid reduces inflammation in postmenopausal women.Nov 01, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2022 Nov 2 ;14(21). Epub 2022 Nov 2. PMID: 36364884

Article Published Date : Nov 01, 2022

Study Type : Human Study

Additional Links

Substances : Chlorogenic Acid, Curcumin, Yoghurt

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Bioavailability Study: Piperine enhances the serum concentration, extent of absorption and bioavailability of curcumin in both rats and humans with no adverse effects.May 01, 1998

Click here to read the entire abstract

Pubmed Data : Planta Med. 1998 May;64(4):353-6. PMID: 9619120

Article Published Date : May 01, 1998

Study Type : Human Study

Additional Links

Substances : Curcumin, Piperidines

[+]

Bioavailable turmeric extract is as effective as paracetamol in reducing pain and other symptoms of knee osteoarthritis.Jan 29, 2021

Click here to read the entire abstract

Pubmed Data : Trials. 2021 Jan 30 ;22(1):105. Epub 2021 Jan 30. PMID: 33516238

Article Published Date : Jan 29, 2021

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Natural Substances Versus Drugs, Plant Extracts

[+]

Bioflavonoid therapy with curcumin and quercetin improves cadaveric renal transplantation in humans. Dec 15, 2005

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr J. 2021 11 13 ;20(1):91. Epub 2021 Nov 13. PMID: 34774052

Article Published Date : Jan 12, 2021

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Inflammation, Overweight

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

[+]

Curcuma longa L. extract supplementation leads to an increase in IL-10 and decreased myoglobin in recreational male runners after a half-marathon race.Jun 30, 2020

Click here to read the entire abstract

Pubmed Data : Eur J Appl Physiol. 2020 Jul ;120(7):1531-1540. Epub 2020 May 2. PMID: 32361773

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2010 Jan 18. Epub 2010 Jan 18. PMID: 20080166

Article Published Date : Jan 18, 2010

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Alcohol Toxicity , Alcoholic Liver Disease

Pharmacological Actions : Hepatoprotective

[+]

Curcumin and Boswellia serrate has beneficial effects on glycoxidation and lipid peroxidation in chronically exercising master athletes.Nov 20, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2016 Nov 21 ;8(11). Epub 2016 Nov 21. PMID: 27879642

Article Published Date : Nov 20, 2016

Study Type : Human Study

Additional Links

Substances : Curcumin, Frankincense

Diseases : Advanced Glycation End products (AGE), Lipid Peroxidation, Oxidative Stress

Pharmacological Actions : Antioxidants

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Curcumin and capsaicin might represent an alternative approach to protect against vitiligo progression.Jan 19, 2010

Click here to read the entire abstract

Pubmed Data : Antioxid Redox Signal. 2010 Jan 19. Epub 2010 Jan 19. PMID: 20085492

Article Published Date : Jan 19, 2010

Study Type : Human Study

Additional Links

Substances : Capsaicin, Curcumin

Diseases : Vitiligo

[+]

Curcumin and lycopene treatment led to significant improvements in patients suffering from oral submucous fibrosis.Jul 29, 2018

Curcumin can effectively decrease the pathological results of osteoarthritis.Apr 21, 2022

Click here to read the entire abstract

Pubmed Data : Altern Ther Health Med. 2022 Apr 22. Epub 2022 Apr 22. PMID: 35452417

Article Published Date : Apr 21, 2022

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Osteoarthritis

Pharmacological Actions : Anti-Inflammatory Agents, Chondroprotective

[+]

Curcumin can improve the mental health and quality of life of primiparous women postpartum due to its efficacy in reducing postpartum anxiety and depression.Apr 24, 2025

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : J Clin Psychopharmacol. 2015 Aug ;35(4):406-10. PMID: 26066335

Article Published Date : Jul 31, 2015

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Depression

Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Natural Substance/Drug Synergy, Significant Treatment Outcome

Problem Substances : Antidepressants

[+]

Curcumin exhibits anti-pre-cancer activity by increasing levels of vitamins C and E, and preventing lipid peroxidation and DNA damage.Jan 01, 2010

Click here to read the entire abstract

Pubmed Data : J Oral Sci. 2010;52(2):251-6. PMID: 20587949

Article Published Date : Jan 01, 2010

Study Type : Human Study

Additional Links

Substances : Curcumin, Vitamin C, Vitamin E

Diseases : DNA damage, Leukoplakia, Lichen Planus, Oxidative Stress, Precancerous Conditions

Pharmacological Actions : Antioxidants

[+]

Curcumin extract improves beta cell functions in obese patients with type 2 diabetes.Sep 30, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr J. 2024 Oct 1 ;23(1):119. Epub 2024 Oct 1. PMID: 39354480

Article Published Date : Sep 30, 2024

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Hypoglycemic Agents, Pancreato Protective Agents

Additional Keywords : Plant Extracts

[+]

Curcumin gel and Aloe Vera gel are effective in improving oral submucous fibrosis symptoms.Jan 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Int J Clin Pharmacol Ther Toxicol. 1986 Dec;24(12):651-4. PMID: 3546166

Article Published Date : Dec 01, 1986

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Inflammation, Postoperative Recovery

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Curcumin has comparable efficacy to metronidazole in treating bacterial vaginosis while demonstrating superior effectiveness and fewer adverse effects in alleviating symptoms.Mar 02, 2025

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2025 Mar 3 ;15(1):7479. Epub 2025 Mar 3. PMID: 40032905

Article Published Date : Mar 02, 2025

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Vaginosis: Bacterial

Pharmacological Actions : Anti-Bacterial Agents

Additional Keywords : Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs

[+]

Curcumin has gall-bladder emptying properties. Jan 01, 2002

Click here to read the entire abstract

Pubmed Data : Asia Pac J Clin Nutr. 2002;11(4):314-8. PMID: 12495265

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Pharm Investig. 2014 Jul ;4(3):138-41. PMID: 25126527

Article Published Date : Jun 30, 2014

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Stomatitis: Aphthous

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Antioxidants, Immunomodulatory

[+]

Curcumin has therapeutic effects in idiopathic inflammatory orbital pseudotumours.Sep 01, 2000

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2000 Sep;14(6):443-7. PMID: 10960899

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Diagn Res. 2014 Aug ;8(8):HC19-24. Epub 2014 Aug 20. PMID: 25302215

Article Published Date : Jul 31, 2014

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Bronchial Asthma

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Curcumin holds good promise in the treatment of oral submucous fibrosis in future.Apr 30, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Oral Maxillofac Pathol. 2015 May-Aug;19(2):145-152. PMID: 26604488

Article Published Date : Apr 30, 2015

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Leukoplakia

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Eur J Appl Physiol. 2015 Sep ;115(9):1949-57. Epub 2015 Apr 29. PMID: 25921600

Article Published Date : Aug 31, 2015

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Muscle Damage: Exercise-Induced

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Curcumin is a safe and tolerable adjunct to FOLFOX chemotherapy in patients with metastatic colorectal cancer.May 26, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutr. 2019 May 27. Epub 2019 May 27. PMID: 31132111

Article Published Date : May 26, 2019

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Cancer Metastasis, Colorectal Cancer

Pharmacological Actions : Chemotherapeutic

[+]

[+]

Curcumin is safe in humans up to 8,000 mg/day when take by mouth for 3 months and has chemopreventive properties. Jul 01, 2001

Click here to read the entire abstract

Pubmed Data : Anticancer Res. 2001 Jul-Aug;21(4B):2895-900. PMID: 11712783

Article Published Date : Jul 01, 2001

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Tumors

Pharmacological Actions : Chemopreventive

Additional Keywords : Curcumin Safety, Herb Safety

[+]

Curcumin may be a safe and effective therapy for maintenance of remission in quiescent UC when given as adjunctive therapy along with mesalamine or sulfasalazine. Dec 31, 2011

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cochrane Database Syst Rev. 2012 ;10:CD008424. Epub 2012 Oct 17. PMID: 23076948

Article Published Date : Dec 31, 2011

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Ulcerative Colitis

Additional Keywords : Complementary Alternative Medicine, Natural Substance/Drug Synergy, Randomized Controlled Trials As Topic

Problem Substances : Mesalamine, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

[+]

Curcumin may be effective in the improvement of cardiac injury after MI through immunomodulatory mechanisms.Dec 31, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Clin Diagn Res. 2015 Aug ;9(8):ZC59-62. Epub 2015 Aug 1. PMID: 26436049

Therapeutic Actions : Exercise

Pharmacological Actions : Antioxidants, Superoxide Dismutase Up-regulation

[+]

curcumin supplementation can improve serum levels of inflammatory cytokines in subjects with NAFLD.Feb 29, 2020

Click here to read the entire abstract

Pubmed Data : Complement Ther Med. 2020 Mar ;49:102322. Epub 2020 Jan 21. PMID: 32147075

Article Published Date : Feb 29, 2020

Study Type : Human Study

Additional Links

Substances : Curcuminoids

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Curcumin supplementation combined with high intensity interval training modulates serum irisin and lipid profile in obese women.Mar 31, 2025

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Contemp Clin Trials Commun. 2025 Apr ;44:101464. Epub 2025 Feb 21. PMID: 40092644

Pubmed Data : Int Urol Nephrol. 2022 Mar 26. Epub 2022 Mar 26. PMID: 35347555

Article Published Date : Mar 25, 2022

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Hemodialysis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Curcumin supplementation influences several biomarkers that may be associated with its antidepressant mechanisms of action.Dec 31, 2014

Click here to read the entire abstract

Pubmed Data : Eur Neuropsychopharmacol. 2015 Jan ;25(1):38-50. Epub 2014 Dec 5. PMID: 25523883

Pubmed Data : Arch Pharm Res. 2024 Dec ;47(12):924-939. Epub 2024 Nov 28. PMID: 39607647

Article Published Date : Nov 30, 2024

Study Type : Human Study

Additional Links

Substances : Curcumin

Pharmacological Actions : Hypolipidemic, Renoprotective

[+]

Curcuminoids represent an effective and safe alternative treatment for OA.Oct 31, 2014

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2014 Nov ;28(11):1625-31. Epub 2014 May 22. PMID: 24853120

Click here to read the entire abstract

Pubmed Data : Am J Epidemiol. 2006 Nov 1;164(9):898-906. Epub 2006 Jul 26. PMID: 16870699

Article Published Date : Nov 01, 2006

Study Type : Human Study

Additional Links

Substances : Curcumin, Curry Spice

Diseases : Dementia

Pharmacological Actions : Neuroprotective Agents

[+]

Dietary supplementation with curcumin reduce circulating levels of glycogen synthase kinase-3β and islet amyloid polypeptide,Apr 08, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2020 Apr 9 ;12(4). Epub 2020 Apr 9. PMID: 32283762

Click here to read the entire abstract

Pubmed Data : J Assoc Physicians India. 2003 Nov ;51:1055-60. PMID: 15260388

Article Published Date : Oct 31, 2003

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Oral Cancer, Oral Submucous Fibrosis

Additional Keywords : Curcumin Safety, Plant Extracts

[+]

Click here to read the entire abstract

Pubmed Data : Eur J Dermatol. 2015 Jun 12. Epub 2015 Jun 12. PMID: 26066761

Article Published Date : Jun 11, 2015

Study Type : Human Study

Additional Links

Substances : Curcumin

Therapeutic Actions : Photodynamic therapy

[+]

Effects of curcumin supplementation on vitamin D levels in women with premenstrual syndrome and dysmenorrhea.Jan 21, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Drugs Context. 2025 ;14. Epub 2025 Jul 9. PMID: 40661790

Article Published Date : Dec 31, 2024

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Acne

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Evaluation of efficacy of curcumin along with lycopene and piperine in the management of oral submucous fibrosis.Jun 30, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Contemp Clin Dent. 2019 Jul-Sep;10(3):531-541. PMID: 32308333

Article Published Date : Jun 30, 2019

Study Type : Human Study

Additional Links

Substances : Curcumin, Lycopene, Piperine

Diseases : Fibrosis

Pharmacological Actions : Anti-Fibrotic

[+]

[+]

Improvement of sulphur mustard-induced chronic pruritus, quality of life and antioxidant status by curcumin: results of a randomised, double-blind, placebo-controlled trial.Sep 30, 2012

Click here to read the entire abstract

Pubmed Data : Br J Nutr. 2012 Oct ;108(7):1272-9. Epub 2011 Nov 18. PMID: 22099425

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2020 Apr ;34(4):896-903. Epub 2019 Dec 1. PMID: 31788880

Article Published Date : Mar 31, 2020

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Anxiety, Depression, Peripheral Neuropathies

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Nanocurcumin has a potentiating anti-inflammatory effect when combined with standard COVID-19 treatment.Dec 31, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Clin Gastroenterol. 2021 Sep 1 ;55(8):702-708. PMID: 32889959

Article Published Date : Aug 31, 2021

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Ulcerative Colitis

Pharmacological Actions : Gastrointestinal Agents

Additional Keywords : Natural Substance/Drug Synergy

[+]

Optimized curcumin, pomegranate extract, and methylsulfonylmethane reduce acute, systemic inflammatory response to a half-marathon race. Jun 30, 2020

Click here to read the entire abstract

Pubmed Data : Altern Ther Health Med. 2020 Jul 1. Epub 2020 Jul 1. PMID: 32619204

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2021 ;12:669362. Epub 2021 May 28. PMID: 34122090

Article Published Date : Dec 31, 2020

Study Type : Human Study

Additional Links

Substances : Curcumin, Piperine

Diseases : Coronavirus Infection

Additional Keywords : Morbidity, Mortality, Risk Reduction

[+]

oral intake of curcumin and vitamin E significantly reduced hot flashes in postmenopausal women.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Physiol. 2021 ;12:712731. Epub 2021 Aug 31. PMID: 34531760

Role of nano curcumin on superoxide dismutase levels in leukoplakia.Dec 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Clin Nutr. 2015 Jan 7. Epub 2015 Jan 7. PMID: 25618800

Article Published Date : Jan 06, 2015

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2016 Jun 8. Epub 2016 Jun 8. PMID: 27270872

Article Published Date : Jun 07, 2016

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective, Hypolipidemic

Additional Keywords : Significant Treatment Outcome

[+]

Short-term supplementation with curcuminoids attenuates systemic oxidative stress in patients with osteoarthritis. Feb 16, 2015

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Pubmed Data : J Diet Suppl. 2015 Feb 17. Epub 2015 Feb 17. PMID: 25688638

Targeting inflammation through diet in patients after spinal cord injury could help with depressive symptoms. Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Neuroinflammation. 2015 ;12(1):204. Epub 2015 Nov 6. PMID: 26545369

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Neuropathol Exp Neurol. 2022 May 13. Epub 2022 May 13. PMID: 35556131

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Pubmed Data : Adv Exp Med Biol. 2021 ;1308:25-35. PMID: 33861434

Article Published Date : Dec 31, 2020

Study Type : Human Study

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Substances : Curcumin

Diseases : Diabetes Mellitus: Type 2, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

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The effect of curcumin supplementation on clinical outcomes and inflammatory markers in patients with ulcerative colitis.Apr 30, 2020

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Pubmed Data : Phytother Res. 2020 May ;34(5):1123-1133. Epub 2019 Dec 4. PMID: 31802559

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View the Evidence: 3984 Abstracts with Curcuminoids Research

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Antihypertensive effects of curcumin/turmeric supplementation in prediabetes and diabetes.Dec 31, 2025

Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults.Mar 31, 2023

Comparing efficacy of curcumin with other treatment modalities in oral submucous fibrosis management.Dec 31, 2023

Curcumin and Curcuma longa extract may improve symptoms and inflammation levels in people with arthritis.Dec 31, 2021

Curcumin and salidroside can improve the course of COPD by regulating blood pressure, inflammation, and the coagulation pathway.Dec 31, 2024

Curcumin in the treatment of inflammation and oxidative stress responses in traumatic brain injury.Dec 31, 2023

Curcumin is likely to be of benefit in mild-to-moderate COVID-19 patients.Jan 13, 2023

Curcumin led to a decrease in the serum CRP and TNF-alpha levels in patients with knee osteoarthritis.Jul 03, 2025

Curcumin may have the potential to enhance cardiometabolic health by reducing hyperglycemia, insulin resistance, and serum TC levels in women with PCOS.Feb 28, 2025

Curcumin supplementation significantly reduces anthropometric indices.Apr 30, 2023

Effects of curcumin on dyslipidemia and body mass index in metabolic disorders.Dec 31, 2024

Effects of curcuminoids plus piperine co-supplementation on liver enzymes and inflammation in adults.Jun 30, 2025

Evaluating the efficacy and safety of Curcuma longa, Boswellia serrata, and their mixed formulation in treating knee osteoarthritis.Oct 11, 2025

Evaluating the efficacy of curcumin in the management of oral potentially malignant disorders.Dec 31, 2023

Safety and efficacy of curcumin in the treatment of ulcerative colitis.Dec 31, 2024

The effect of highly bioavailable forms of curcumin on lipoprotein(a) plasma levels.Apr 16, 2025

The effectiveness of curcumin, resveratrol, and silymarin on MASLD.Nov 30, 2024

The effects of curcumin plus piperine co-administration on inflammation and oxidative stress.Mar 28, 2024

The efficacy of curcumin application to melanoma in mice.Jul 31, 2024

The findings of this systematic review and meta-analysis support the potential effect of curcumin on the management of NAFLD.Dec 31, 2024

These findings suggest that curcumin may be used as an adjunct therapy in individuals with oxidative stress.Nov 30, 2019

A review of the beneficial effects of antioxidants on Helicobacter pylori eradication.Nov 30, 2018

Anti-inflammatory effects of oral supplementation with curcumin.Aug 08, 2021

Curcumin administration reduces depressive symptoms in patients with major depression.Nov 26, 2015

Curcumin as an ajuvant treatment of depression: mechanisms of action and application prospects.Dec 31, 2019

Curcumin for depression: a meta-analysis.Aug 18, 2019

Curcumin is a safe, natural bioactive substance that can effectively prevent and treat oral mucositis.Dec 31, 2020

Curcumin may provide great potential effects against diabetic kidney disease. Dec 31, 2020

Curcumin or combined curcuminoids are effective in lowering the fasting blood glucose concentrations of individuals with dysglycemia.Sep 15, 2017

Curcumin supplementation has favorable effect on metabolic markers and anthropometric parameters in patients with NAFLD.Dec 31, 2019

Curcuminoids may have some beneficial effects on knee pain and quality of life in patients with knee osteoarthritis.Mar 31, 2017

Curcuminoids supplements may be a safe and effective strategy to improve pain severity.Dec 13, 2015

Effect of curcumin plus piperine co-supplementation on glycemic control in adults.Nov 30, 2025

Effects of Curcuma as an adjunct therapy on periodontal disease.Oct 31, 2021

Effects of curcuminoids plus piperine co-supplementation on serum lipid profile in adults.Dec 31, 2025

Efficacy and safety of adjuvant curcumin therapy in ulcerative colitisJan 24, 2022

Efficacy and safety of dietary polyphenols in rheumatoid arthritis.Dec 31, 2022

Efficacy and safety of turmeric dietary supplementation on proteinuria in CKD.Apr 30, 2022

Impact of exercise intervention with or without curcumin supplementation on body fat composition, glucose, and lipid metabolism in obese adults.Feb 28, 2025

Influence of phytosomal curcumin on anthropometric indices for nonalcoholic fatty liver disease.Dec 26, 2024

Meta-analysis of randomized controlled trials of 4 weeks or longer suggest that curcumin may afford some protection against oxidative stress.Jan 11, 2018

Meta-analysis of the effect of curcumin supplementation on skeletal muscle damage status.Dec 31, 2023

Meta-analysis: curcumin down-regulates inteleukin-6. Jul 04, 2016

Photodynamic therapy for oral candidiasis in human clinical trials.Jul 31, 2025

Potential therapeutic effects of curcumin on glycemic and lipid profile in uncomplicated type 2 diabetes.Jan 26, 2021

Protective effects of curcumin on epileptic rodent models by alleviating oxidative stress and inflammation.Dec 31, 2024

The effect of curcumin as an adjunct in the treatment of chronic periodontitis.Oct 31, 2021

The potential of curcumin for treating spinal cord injury.May 03, 2022

The results of this study suggest that the administration of curcumin supplements may be a beneficial intervention for enhancing glycemic indices.Nov 30, 2024

These RCTs provide scientific evidence that supports the efficacy of turmeric extract and curcumin in the treatment of arthritis.Jul 31, 2016

This meta-analysis of RCTs suggested a significant effect of curcumin in lowering circulating TNF-α concentration.Mar 25, 2016

Turmeric and curcuminiods ameliorate disorders of glycometabolism among subjects with metabolic diseases.Feb 06, 2022

Use of curcumin in achieving clinical and endoscopic remission in ulcerative colitis.Jan 09, 2018

Cancer stem cells as a prognostic biomarker and therapeutic target using curcumin/ piperine extract for multiple myeloma.Sep 30, 2022

A bioavailable form of curcumin is well-tolerated and can positively influence weight management in overweight people.Oct 31, 2015

A combination of curcumin and fennel essential oil significantly improved symptoms and quality of life in IBS patients over 30 days.May 31, 2016

A combination of curcumin and melatonin supplemented using an oral cosmetic vehicle has the capacity to decrease the level of periodontal pathogenic bacteria.Oct 30, 2024

A combination of hydroxytyrosol, omega-3 fatty acids and curcumin improves pain and inflammation among early stage breast cancer patients.Mar 31, 2019

A combination of Saw Palmetto, Nettle, Curcumin and Quercetin significantly improves treatment outcome of prulifloxacin in bacterial prostatitis patients. Jun 01, 2009

A complex of curcumin and phosphatidylcholine is effective in reducing the symptoms of ostearthritis.Dec 01, 2010

A curcumin extract is appropriate for the care of patients with joint problems and may also contribute to the regeneration of cartilage.Dec 31, 2013

A curcumin formula decreased the median polyp number in familial adenomatous polyposis patients. Nov 21, 2022

A daily dose of 3.6 g curcumin achieves pharmacologically efficacious levels in the colorectum with negligible distribution of curcumin outside the gut.Jan 01, 2005

A hot water extract of C. longa may help to improve systemic glucose metabolism in people with chronic low-grade inflammation.Sep 12, 2022

A minor metabolite from Curcuma longa effective against metabolic syndrome.May 21, 2023

A pilot study to examine the effects of an anti-inflammatory supplement on eicosanoid derivatives in patients with chronic kidney disease.Jul 31, 2017

A polyherbal cream application of curcumin had a HPV clearance rate of 81.3%. Dec 31, 2012

A standardized preparation of curcuminoids compares favorably with atorvastatin on endothelial dysfunction in association with reductions in inflammatory cytokines and markers of oxidative stress. Jan 01, 2008

A supplement containing huperzine A and curcumin in dementia patients and individuals with mild cognitive impairment had beneficial effects.Dec 31, 2017

A topical preparation of curcumin successfully decreased the markers of lactational mastitis such as pain, breast tension and erythema within 72 hours of administration.Aug 31, 2014

Add-on treatment with curcumin has antidepressive effects in thai patients with major depression.Dec 31, 2017

Curcuminoids

View the Evidence:
3984 Abstracts with Curcuminoids Research