Dandelion

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106 Diseases Researched for Dandelion
NameACCKFocus
Oxidative Stress1928Locked
Inflammation1825Locked
Lipopolysaccharide-Induced Toxicity1518Locked
Obesity517Locked
Colitis416Locked
Alcohol Toxicity 612Locked
Chemically-Induced Liver Damage612Locked
Depression212Locked
Cytomegalovirus Infections110Locked
Diarrhea110Locked
Dyspepsia110Locked
Tonsillitis110Locked
Water Retention110Locked
Acetaminophen (Tylenol) Toxicity 36Locked
Diabetes Mellitus: Type 256Locked
Hepatitis B 26Locked
Liver Cancer56Locked
Alcoholic Liver Disease35Locked
Colitis: Ulcerative15Locked
Lipid Peroxidation35Locked
Pancreatic Cancer15Locked
Staphylococcus aureus infection35Locked
Dysbiosis24Locked
Leukemia24Locked
Liver Damage24Locked
Liver Damage: Drug-Induced24Locked
Lung Injury: Acute24Locked
Rheumatoid Arthritis24Locked
Breast Cancer23Locked
Colorectal Cancer23Locked
Hyperglycemia33Locked
Hypoglycemia23Locked
Mastitis23Locked
Neurodegenerative Diseases33Locked
Prostate Cancer23Locked
Urolithiasis23Locked
Advanced Glycation End products (AGE)22Locked
Arthritis12Locked
Asthma12Locked
Brain Inflammation 22Locked
Breast Cancer: Chemically-Induced12Locked
Breast Cancer: Triple Negative 22Locked
Cancers: All12Locked
Carcinoma: Non-Small-Cell Lung22Locked
Cardiovascular Diseases22Locked
Chemotherapy-Induced Toxicity: Mitomycin-C12Locked
Colon Cancer12Locked
DNA damage12Locked
Depressive Disorder12Locked
Diabetes Mellitus: Type 112Locked
Escherichia coli Infections12Locked
Gastritis12Locked
Hepatic Steatosis12Locked
High Fat Diet12Locked
Hyperlipidemia12Locked
Infertility: Female12Locked
Inflammatory Bowel Diseases12Locked
Kidney Damage: Chemically-Induced12Locked
Kidney Damage: Drug-Induced12Locked
Kidney Stones22Locked
Klebsiella Infections12Locked
Lead Poisoning12Locked
Liver Failure: Acute12Locked
Liver Fibrosis12Locked
Lung Injury: Neutrophil-Induced12Locked
Mercury Poisoning12Locked
Pancreatitis12Locked
Postmenopausal Disorders: Weight Gain/Obesity12Locked
Prenatal Chemical Exposures12Locked
Prenatal Nutrition: Health of the Offspring12Locked
Skin Cancer12Locked
Ulcerative Colitis12Locked
Atherosclerosis11Locked
Bacillus Cereus infection11Locked
Bladder Stones11Locked
Brain: Microglial Activation11Locked
Brain: Oxidative Stress11Locked
Cancers: Drug Resistant11Locked
Candida Albicans11Locked
Cerebral Ischemia11Locked
Dengue11Locked
Diabetes Mellitus: Type 2: Prevention11Locked
Endocrine Diseases11Locked
Endocrine Imbalances11Locked
Fungal Infection11Locked
Gastric Cancer11Locked
Glutathione Deficiency 11Locked
Gram-Negative Bacterial Infections11Locked
Gram-Positive Bacterial Infections11Locked
Heavy Metal Toxicity11Locked
Hepatitis C11Locked
Hepatoma11Locked
Hydrogen Peroxide Induced Toxicity11Locked
Hypogonadism11Locked
Influenza11Locked
Ischemia11Locked
Kidney Damage11Locked
Leukemia: Multi-Drug Resistant11Locked
Lung Cancer11Locked
Lung Injury: Smoke-Induced11Locked
Melanoma11Locked
Neuroblastoma11Locked
Osteoarthritis11Locked
Prostatic Hyperplasia: Benign11Locked
Staphylococcus aureus: Methicillin-resistant (MRSA)11Locked
Ultraviolet Radiation Induced Damage11Locked
87 Pharmacological Actions Researched for Dandelion
NameACCKFocus
Anti-Inflammatory Agents3350Locked
Antioxidants3649Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor2034Locked
Hepatoprotective1223Locked
Interleukin-6 Downregulation1120Locked
Antiviral Agents619Locked
Interleukin-1 beta downregulation1219Locked
Apoptotic1117Locked
Antiproliferative 1013Locked
Enzyme Inhibitors313Locked
NF-kappaB Inhibitor1013Locked
Nrf2 activation913Locked
Antidepressive Agents212Locked
Diuretics211Locked
Brain-derived neurotrophic factor modulator110Locked
Enzyme Inhibitors: Pancreatic Lipase110Locked
Heme oxygenase-1 up-regulation610Locked
Cyclooxygenase 2 Inhibitors68Locked
Malondialdehyde Down-regulation48Locked
Hypoglycemic Agents67Locked
Hypolipidemic47Locked
Neuroprotective Agents67Locked
Superoxide Dismutase Up-regulation47Locked
Autophagy Up-regulation26Locked
Prostaglandin PGE2 downregulation46Locked
Alpha-glucosidase inhibitor 55Locked
Anti-metastatic45Locked
Chemopreventive25Locked
Cytoprotective15Locked
Immunomodulatory35Locked
Nitric Oxide Inhibitor45Locked
Renoprotective35Locked
Anti-Apoptotic34Locked
Gastrointestinal Agents24Locked
Interleukin-8 downregulation34Locked
Anticarcinogenic Agents23Locked
Antimicrobial33Locked
Chemosensitizer23Locked
Chemotherapeutic13Locked
Alpha-amylase inhibitor22Locked
Analgesics22Locked
Anti-Asthmatic Agents12Locked
Anti-Bacterial Agents12Locked
Anti-Fibrotic12Locked
Anti-Glycation Agents22Locked
Anti-Platelet22Locked
Anti-Ulcer Agents12Locked
Antimutagenic Agents12Locked
Antiurolithiatic12Locked
Cell cycle arrest22Locked
Contraceptive Agents: Male12Locked
ER alpha receptor up-regulation12Locked
ER beta receptor up-regulation12Locked
Estrogen Receptor Modulators12Locked
Follicle-stimulating hormone receptor (FSHR) up-regulation12Locked
Gastroprotective12Locked
Glutathione Upregulation 22Locked
Heme oxygenase-1 inducer22Locked
Interferon Gamma Reducer12Locked
MicroRNA modulator22Locked
Progesterone receptor (PR) up-regulation12Locked
Radioprotective12Locked
STAT3 Inhibitor12Locked
Angiogenesis Inhibitors11Locked
Anti-Allergic Agents11Locked
Anti-Angiogenic11Locked
Anticoagulants11Locked
Antifungal Agents11Locked
Antiparasitic Agents11Locked
Cardioprotective11Locked
Caspase-3 Activation11Locked
Caspase-8 activation11Locked
Cholagogues and Choleretics11Locked
Cyclooxygenase Inhibitors11Locked
Cytotoxic11Locked
Hypnotics and Sedatives11Locked
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor11Locked
Interleukin-1 alpha downregulation11Locked
Interleukin-1 alpha upregulation11Locked
Interleukin-10 downregulation11Locked
Intracellular adhesion molecule-1 (ICAM-1)11Locked
Matrix Metalloproteinase-13 (MMP-13) Inhibitor11Locked
Matrix metalloproteinase-1 (MMP-1) inhibitor11Locked
Matrix metalloproteinase-3 (MMP-3) inhibitor11Locked
Postaglandin PGE2 downregulation 11Locked
TRAIL sensitizer11Locked
Vascular Endothelial Growth Factor Inhibitors11Locked
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View the Evidence:
182 Abstracts with Dandelion Research

[+]

A Chinese herbal formula containing Paris polyphylla, Dandelion, Woad, and Licorice appears safe and effective in reducing cytomegalovirus infection activity in pregnant women. Apr 01, 2000

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2000 Apr;20(4):245-7. PMID: 11789257
Article Published Date : Apr 01, 2000
Study Type : Human Study
Additional Links
Substances : Dandelion , Licorice, Paris polyphylla, Woad
Diseases : Cytomegalovirus Infections
Pharmacological Actions : Antiviral Agents
[+]

A combination of artichoke leaf, dandelion root, turmeric root and rosemary essential oil has therapeutic actions in relieving symptoms in functional dyspepsia.Jun 01, 2010

Pubmed Data : Minerva Gastroenterol Dietol. 2010 Jun;56(2):93-9. PMID: 20485248
Article Published Date : Jun 01, 2010
Study Type : Human Study
Additional Links
Substances : Artichoke, Dandelion , Rosemary, Turmeric
Diseases : Dyspepsia
Additional Keywords : Plant Extracts
[+]

Dandelion has a diuretic effect in human subjects. Aug 01, 2009

Pubmed Data : J Altern Complement Med. 2009 Aug;15(8):929-34. PMID: 19678785
Article Published Date : Aug 01, 2009
Study Type : Human Study
Additional Links
Substances : Dandelion
Diseases : Water Retention
Pharmacological Actions : Diuretics
Additional Keywords : Plant Extracts
[+]

Dandelion has pancreatic lipase activity which may have a therapeutic role in obesity. Jan 01, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2008;2(4):200-3. Epub 2008 Dec 31. PMID: 20016719
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Substances : Dandelion
Diseases : Obesity
Pharmacological Actions : Enzyme Inhibitors, Enzyme Inhibitors: Pancreatic Lipase
[+]

Dandelion, St. Johns Wort, Melissa (Lemonbalm), Marigold, and Fennel have therpaeutic effects in treating colitis and diarrhea syndrome. Jan 01, 1981

Pubmed Data : Vutr Boles. 1981;20(6):51-4. PMID: 7336706
Article Published Date : Jan 01, 1981
Study Type : Human Study
Additional Links
Substances : Dandelion , Fennel, Marigold, Melissa (Lemonbalm), St. Johns Wort
Diseases : Colitis, Diarrhea
Additional Keywords : Plant Extracts
[+]

Imupret is a safe and effective product for treatment of acute non-bacterial tonsillitis in children aged 6-18 years.Oct 23, 2018

Pubmed Data : Am J Otolaryngol. 2018 Oct 24. Epub 2018 Oct 24. PMID: 30554882
Article Published Date : Oct 23, 2018
Study Type : Human Study
Additional Links
Substances : Dandelion , Horsetail, Marshmallow Root, Oak, Walnut, Yarrow
Diseases : Tonsillitis
Additional Keywords : Plant Extracts
[+]

T. officinale exerts significant antidepressant effects in a mouse model of depression.Jan 12, 2019

Pubmed Data : Med Sci Monit. 2019 Jan 13 ;25:389-394. Epub 2019 Jan 13. PMID: 30636257
Article Published Date : Jan 12, 2019
Study Type : Human Study
Additional Links
Substances : Dandelion
Diseases : Depression
Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator
[+]

Dandelion root extract can be an effective anti-colitis complex mixture.May 07, 2018

Pubmed Data : J Nat Med. 2018 May 8. Epub 2018 May 8. PMID: 29740735
Article Published Date : May 07, 2018
Study Type : Animal Study, Human In Vitro
Additional Links
Substances : Dandelion
Diseases : Colitis: Ulcerative
Pharmacological Actions : Cytoprotective
[+]

Dandelion root induces selective apoptosis and autophagy in human pancreatic cancer cells in a dose and time dependent manner.Sep 30, 2012

Pubmed Data : Pancreas. 2012 Oct ;41(7):1039-47. PMID: 22647733
Article Published Date : Sep 30, 2012
Study Type : Human In Vitro
Additional Links
Substances : Dandelion
Diseases : Pancreatic Cancer
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
Additional Keywords : Selective Cytotoxicity
[+]

The results demonstrate the potent antiviral effect of T. mongolicum against hepatitis B virus.Mar 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2014 Apr ;9(4):1381-7. Epub 2014 Jan 29. PMID: 24481875
Article Published Date : Mar 31, 2014
Study Type : Animal Study, Human In Vitro
Additional Links
Substances : Dandelion
Diseases : Hepatitis B
Pharmacological Actions : Antiviral Agents
Additional Keywords : Plant Extracts
[+]

Hyperthyroidism treatment by alternative therapies based on cupping and dietary-herbal supplementation.Aug 11, 2021

Pubmed Data : Drug Metab Pers Ther. 2021 Aug 12. Epub 2021 Aug 12. PMID: 34388334
Article Published Date : Aug 11, 2021
Study Type : Human: Case Report
Additional Links
Substances : Barley Grass, Dandelion , Fenugreek, Nettle, Royal Jelly, Turmeric
Diseases : Hyperthyroidism
Therapeutic Actions : Cupping
[+]

Induction of P-glycoprotein expression by dandelion in tumor and heart tissues: Impact on the anti-tumor activity and cardiotoxicity of doxorubicin.Jun 11, 2022

Pubmed Data : Phytomedicine. 2022 Jun 12 ;104:154275. Epub 2022 Jun 12. PMID: 35760022
Article Published Date : Jun 11, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Cardioprotective, Chemoprotective Agents
[+]

Taraxasterol prompted the anti-tumor effect in mice burden hepatocellular carcinoma by regulating T lymphocytes.May 15, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Death Discov. 2022 May 16 ;8(1):264. Epub 2022 May 16. PMID: 35577774
Article Published Date : May 15, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Immunomodulatory
[+]

The use of natural health products especially papaya leaf extract and dandelion root extract in previously untreated chronic myelomonocytic leukemia.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Case Rep Hematol. 2018 ;2018:7267920. Epub 2018 Dec 18. PMID: 30662779
Article Published Date : Dec 31, 2017
Study Type : Human: Case Report
Additional Links
Substances : Dandelion , Papaya
Diseases : Leukemia
Pharmacological Actions : Chemopreventive, Chemotherapeutic
Additional Keywords : Plant Extracts
[+]

A herbal preparation suppressed 80 % of DNA strand breaks in the liver, kidney, lung, brain and testicles of mice exposed to mitomycin C.Feb 09, 2015

Pubmed Data : J Nat Med. 2015 Feb 10. Epub 2015 Feb 10. PMID: 25666712
Article Published Date : Feb 09, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Barberry, Burdock, Dandelion
Diseases : Chemotherapy-Induced Toxicity: Mitomycin-C, DNA damage
Pharmacological Actions : Antimutagenic Agents
Additional Keywords : Drug: Mitomycin, Plant Extracts
[+]

A water extract of dandelion roots and leaves demonstrated antidepressant effects in an animal model.Jul 31, 2014

Pubmed Data : Pharm Biol. 2014 Aug ;52(8):1028-32. Epub 2014 Mar 10. PMID: 24611722
Article Published Date : Jul 31, 2014
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Depression, Depressive Disorder
Pharmacological Actions : Antidepressive Agents
Additional Keywords : Plant Extracts
[+]

A water extract of Taraxacum mongolicum had a protective effect on lipopolysaccharide induced acute lung injury in mice.Jun 19, 2015

Pubmed Data : J Ethnopharmacol. 2015 Jun 20 ;168:349-55. Epub 2015 Apr 8. PMID: 25861954
Article Published Date : Jun 19, 2015
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute, Lung Injury: Neutrophil-Induced
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

Administration of the herbal extracts and mixture with probiotics can enhance the body defense and contain protective factor against mercury neurotoxicity.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Rep. 2018 ;5:1069-1077. Epub 2018 Oct 27. PMID: 30425928
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Cilantro, Dandelion , Date Seeds, Probiotics
Diseases : Mercury Poisoning
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Mercury
[+]

An extract of natural herbals restores antitumor immunosurveillance and can be applied for prevention or treatment of inflammation-related cancers.Mar 21, 2018

Pubmed Data : Biomed Pharmacother. 2018 Mar 22 ;102:420-427. Epub 2018 Mar 22. PMID: 29574282
Article Published Date : Mar 21, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dandelion , Fig, Ginseng
Diseases : Cancers: All, Liver Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, NF-kappaB Inhibitor
[+]

Anti-inflammatory and anti-apoptosis activity of taraxasterol in ulcerative colitis in vitro and in vivo.Aug 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2019 Sep ;18(3):1745-1751. Epub 2019 Jul 5. PMID: 31410133
Article Published Date : Aug 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-inflammatory effects and mechanisms of dandelion.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:906927. Epub 2022 Aug 25. PMID: 36091818
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Antiurolithiatic effect of the taraxasterol on ethylene glycol induced kidney calculi.Nov 29, 2017

Pubmed Data : Urolithiasis. 2017 Nov 30. Epub 2017 Nov 30. PMID: 29189886
Article Published Date : Nov 29, 2017
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Alcohol Toxicity , Urolithiasis
Pharmacological Actions : Antiurolithiatic
[+]

Atractylodes macrocephala or Taraxacum herba extracts can be considered natural agents that can prevent inflammatory bowel disease relapse.Sep 14, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Gut Liver. 2017 Sep 15 ;11(5):655-666. PMID: 28651306
Article Published Date : Sep 14, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Bai Zhu, Dandelion
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts, Risk Reduction, Superiority of Natural Substances versus Drugs
[+]

Beneficial effect of Taraxacum coreanum Nakai via the activation of LKB1-AMPK signalling pathway on obesity.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:6655599. Epub 2021 Jan 17. PMID: 33531919
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Obesity
Pharmacological Actions : Hypolipidemic
[+]

Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis.Aug 08, 2022

Pubmed Data : Int Immunopharmacol. 2022 Aug 9 ;111:109129. Epub 2022 Aug 9. PMID: 35961266
Article Published Date : Aug 08, 2022
Study Type : Animal Study
Additional Links
Substances : Chicoric Acid, Dandelion
Diseases : Inflammation, Osteoarthritis
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Heme oxygenase-1 up-regulation, NF-kappaB Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Combination effects of metformin and a mixture of lemon balm and dandelion on high-fat diet-induced metabolic alterations.Mar 17, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2022 Mar 18 ;11(3). Epub 2022 Mar 18. PMID: 35326230
Article Published Date : Mar 17, 2022
Study Type : Animal Study
Additional Links
Substances : Dandelion , Lemon Balm
Diseases : High Fat Diet, Insulin Resistance, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Antioxidants, Hepatoprotective, Renoprotective
Additional Keywords : Natural Substance/Drug Synergy
[+]

Comparison of ameliorative effects of Taraxacum syriacum and N-acetylcysteine against acetaminophen-induced oxidative stress in the liver and kidney.Sep 23, 2020

Pubmed Data : J Biochem. 2020 Sep 24. Epub 2020 Sep 24. PMID: 32970799
Article Published Date : Sep 23, 2020
Study Type : Animal Study
Additional Links
Substances : Dandelion , NAC (N-acetyl-L-cysteine)
Diseases : Acetaminophen (Tylenol) Toxicity , Kidney Damage: Drug-Induced, Liver Damage: Drug-Induced
Pharmacological Actions : Antioxidants, Hepatoprotective, Renoprotective
Problem Substances : Acetaminophen, Paracetamol
[+]

Dandelion (Taraxacum officinale) decreases male rat fertility in vivo.Apr 26, 2011

Pubmed Data : J Ethnopharmacol. 2011 Apr 26;135(1):102-9. Epub 2011 Feb 24. PMID: 21354287
Article Published Date : Apr 26, 2011
Study Type : Animal Study
Additional Links
Substances : Dandelion
Pharmacological Actions : Contraceptive Agents: Male
[+]

Dandelion (Taraxacum officinale) protects rats from chemical induced pancreatitis.Jan 28, 2005

Pubmed Data : World J Gastroenterol. 2005 Jan 28;11(4):597-9. PMID: 15641154
Article Published Date : Jan 28, 2005
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Pancreatitis
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Dandelion and lemongrass extracts were able to significantly reduce the tumour burden in prostate cancer xenograft models.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:2951428. Epub 2019 Jul 17. PMID: 31391857
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Dandelion , Lemongrass
Diseases : Prostate Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer
Additional Keywords : Natural Substance/Drug Synergy, Selective Cytotoxicity
[+]

Dandelion contains compounds which protect against chemically-induced liver toxicity in mice.Jun 01, 2010

Pubmed Data : Acta Biol Hung. 2010 Jun;61(2):175-90. PMID: 20519172
Article Published Date : Jun 01, 2010
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Alcohol Toxicity , Chemically-Induced Liver Damage, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Hepatoprotective
Additional Keywords : Plant Extracts
[+]

Dandelion extract protects against acute, chemically-induced liver injury. Sep 01, 2010

Pubmed Data : Phytother Res. 2010 Sep;24(9):1347-53. PMID: 20812277
Article Published Date : Sep 01, 2010
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Chemically-Induced Liver Damage, Inflammation, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Dandelion extract relaxes mouse airway smooth muscle by blocking VDLCC and NSCC channels.Oct 27, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Biosci. 2020 Oct 28 ;10(1):125. Epub 2020 Oct 28. PMID: 33292472
Article Published Date : Oct 27, 2020
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Asthma
Pharmacological Actions : Anti-Asthmatic Agents
[+]

Dandelion extract up-regulates reproductive hormone receptor expression in mice.Sep 01, 2007

Pubmed Data : Int J Mol Med. 2007 Sep;20(3):287-92. PMID: 17671731
Article Published Date : Sep 01, 2007
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Infertility: Female
Pharmacological Actions : ER alpha receptor up-regulation, ER beta receptor up-regulation, Estrogen Receptor Modulators, Follicle-stimulating hormone receptor (FSHR) up-regulation, Progesterone receptor (PR) up-regulation
Additional Keywords : Estrogen Receptor Beta, Plant Extracts
[+]

Dandelion extracts pretreatment protects against acetaminophen-induced hepatic injury.Nov 23, 2021

Pubmed Data : Chin J Integr Med. 2021 Nov 24. Epub 2021 Nov 24. PMID: 34816363
Article Published Date : Nov 23, 2021
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage: Drug-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Acetaminophen, Paracetamol
[+]

Dandelion has antifibrotic activity in chemically-induced liver damage in mice.Aug 09, 2010

Pubmed Data : J Ethnopharmacol. 2010 Aug 9;130(3):569-77. Epub 2010 Jun 2. PMID: 20561925
Article Published Date : Aug 09, 2010
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Chemically-Induced Liver Damage, Liver Fibrosis, Oxidative Stress
Pharmacological Actions : Anti-Fibrotic, Hepatoprotective, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

Dandelion has hepatoprotective effects against alcoholic liver damage.Jun 01, 2010

Pubmed Data : Food Chem Toxicol. 2010 Jun;48(6):1632-7. Epub 2010 Mar 27. PMID: 20347918
Article Published Date : Jun 01, 2010
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Alcohol Toxicity , Chemically-Induced Liver Damage, Oxidative Stress
Pharmacological Actions : Hepatoprotective, Malondialdehyde Down-regulation
Additional Keywords : Plant Extracts
[+]

Dandelion has lipid lowering and antioxidant properties. Jan 01, 2010

Pubmed Data : Int J Mol Sci. 2010;11(1):67-78. Epub 2010 Jan 6. PMID: 20162002
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Hyperlipidemia, Oxidative Stress
Pharmacological Actions : Antioxidants, Hypolipidemic
[+]

Dandelion leaf and petal phenolic fractions, enriched with l-chicoric acid, are promising plant materials that may exert in vivo beneficial antioxidant effects. Feb 02, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Feb 3 ;9(2). Epub 2020 Feb 3. PMID: 32028583
Article Published Date : Feb 02, 2020
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Hypolipidemic
[+]

Dandelion polyphenols protect against acetaminophen-induced hepatotoxicity.Jan 31, 2020

Pubmed Data : Chin J Nat Med. 2020 Feb ;18(2):103-113. PMID: 32172946
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Substances : Dandelion , Polyphenols
Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage: Drug-Induced
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Hepatoprotective, Nrf2 activation
Problem Substances : Acetaminophen, Paracetamol
[+]

Dandelion polysaccharide can decrease the level of IL-6 in rats with ulcerative colitis.May 07, 2017

Pubmed Data : Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2017 May 8 ;33(5):422-425. PMID: 29926586
Article Published Date : May 07, 2017
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, STAT3 Inhibitor
Additional Keywords : Polysaccharides
[+]

Dandelion prevents chemical carcinogenesis.Jan 01, 2008

Pubmed Data : J Exp Ther Oncol. 2008;7(4):275-84. PMID: 10408234
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Skin Cancer
Pharmacological Actions : Anticarcinogenic Agents
Additional Keywords : Plant Extracts
[+]

Dandelion protects against lipopolysaccharide-induced acute lung injury in mice.Jul 20, 2010

Pubmed Data : J Ethnopharmacol. 2010 Jul 20;130(2):392-7. Epub 2010 May 25. PMID: 20510343
Article Published Date : Jul 20, 2010
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Dandelion root extract affects ESCC progression via regulating multiple signal pathways.Oct 03, 2021

Pubmed Data : Food Funct. 2021 Oct 4 ;12(19):9486-9502. Epub 2021 Oct 4. PMID: 34476429
Article Published Date : Oct 03, 2021
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Esophageal Cancer
Pharmacological Actions : Antiproliferative
[+]

Dandelion root extract is effective as anticancer herbal agent.Aug 19, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Rep. 2018 Aug 20. Epub 2018 Aug 20. PMID: 30126855
Article Published Date : Aug 19, 2018
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Breast Cancer, Breast Cancer: Chemically-Induced
Pharmacological Actions : Antiproliferative , Chemopreventive
[+]

Dandelion root extracts abolish MAPK pathways to ameliorate experimental mouse ulcerative colitis.Feb 16, 2022

Pubmed Data : Adv Clin Exp Med. 2022 Feb 17. Epub 2022 Feb 17. PMID: 35178902
Article Published Date : Feb 16, 2022
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Gastroprotective
[+]

Dandelion sterol improves diabetes mellitus-induced renal injury in in vitro and in vivo study.Aug 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2021 Sep ;9(9):5183-5197. Epub 2021 Jul 28. PMID: 34532027
Article Published Date : Aug 31, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Dietary dandelion extracts promoted intestine health by improving intestine morphology, immunity, antioxidant abilities and intestinal barrier.Dec 15, 2017

Pubmed Data : Fish Shellfish Immunol. 2017 Dec 16 ;73:197-206. Epub 2017 Dec 16. PMID: 29258755
Article Published Date : Dec 15, 2017
Study Type : Animal Study
Additional Links
Substances : Dandelion
Pharmacological Actions : Antioxidants, Gastrointestinal Agents, Immunomodulatory
Additional Keywords : Antioxidants, Dandelion, Gastrointestinal Agents, Gene Expression Regulation, Immunomodulatory
[+]

Differential effect of dandelion root extract on hepatic and testicular tissues of rats exposed to ionizing radiation.Jun 27, 2019

Pubmed Data : Mol Biol Rep. 2019 Jun 28. Epub 2019 Jun 28. PMID: 31254243
Article Published Date : Jun 27, 2019
Study Type : Animal Study
Additional Links
Substances : Dandelion
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Radioprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Anti Therapeutic Actions : Radation Exposure: Low-Dose
[+]

Effects of taraxasterol against ethanol and high-fat diet-induced liver injury.Nov 30, 2020

Pubmed Data : Life Sci. 2020 Dec 1 ;262:118546. Epub 2020 Oct 6. PMID: 33035580
Article Published Date : Nov 30, 2020
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Alcohol Toxicity , Alcoholic Liver Disease, High Fat Diet, Inflammation, Liver Damage, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, NF-kappaB Inhibitor, Nrf2 activation
[+]

Gastroprotective effects of the aqueous extract from Taraxacum officinale.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:8987232. Epub 2021 Dec 21. PMID: 34970327
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Gastrointestinal Agents, Gastroprotective
[+]

H. erinaceus has an anti-obesity effect during menopause because it decreases the ability to absorb lipids.Jun 30, 2017

Pubmed Data : J Nat Med. 2017 Jul ;71(3):482-491. Epub 2017 Feb 8. PMID: 28181079
Article Published Date : Jun 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Obesity, Postmenopausal Disorders: Weight Gain/Obesity
Additional Keywords : Anti-Obesity Agents
[+]

Herbal mixture of Carthamus tinctorius L. seed and Taraxacum coreanum attenuates amyloid beta-Induced cognitive dysfunction.Jan 05, 2022

Pubmed Data : Foods. 2022 Jan 6 ;11(2). Epub 2022 Jan 6. PMID: 35053874
Article Published Date : Jan 05, 2022
Study Type : Animal Study
Additional Links
Substances : Dandelion , Safflower
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Hypoglycemic effect of Taraxacum officinale root extract and its synergism with Radix Astragali extract.Mar 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2021 Apr ;9(4):2075-2085. Epub 2021 Feb 26. PMID: 33841825
Article Published Date : Mar 31, 2021
Study Type : Animal Study
Additional Links
Substances : Astragalus, Dandelion
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2, Hypoglycemia
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Natural Substance Synergy
[+]

Mechanistic role of methanolic extract of Taraxacum officinale roots as cardioprotective against ischemia-reperfusion injury-induced myocardial infarction.Jan 02, 2023

Pubmed Data : Appl Biochem Biotechnol. 2023 Jan 3. Epub 2023 Jan 3. PMID: 36595191
Article Published Date : Jan 02, 2023
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Myocardial Infarction, Myocardial Ischemia
Pharmacological Actions : Cardioprotective
[+]

Mulberry and dandelion extracts may have the potential to improve some of the pathologies associated with excess alcohol consumption.Jun 30, 2018

Pubmed Data : Exp Biol Med (Maywood). 2018 Jul ;243(11):882-894. PMID: 30105955
Article Published Date : Jun 30, 2018
Study Type : Animal Study
Additional Links
Substances : Dandelion , Mulberry
Diseases : Alcoholic Liver Disease, Chemically-Induced Liver Damage, Dysbiosis, Hepatic Steatosis
Pharmacological Actions : Hepatoprotective
[+]

Oral administration of dandelion root extract inhibited the growth of human colon xenograft models by more than 90%.Aug 21, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2016 Aug 22. Epub 2016 Aug 22. PMID: 27564258
Article Published Date : Aug 21, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Colon Cancer, Colorectal Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
Additional Keywords : Dose Response, Plant Extracts, Selective Cytotoxicity
[+]

Organic acid component from Taraxacum mongolicum alleviates inflammatory injury in lipopolysaccharide-induced acute tracheobronchitis.Apr 30, 2016

Pubmed Data : Int Immunopharmacol. 2016 May ;34:92-100. Epub 2016 Feb 28. PMID: 26930562
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Pharmacopuncture of Taraxacum platycarpum extract reduces localized fat by regulating the lipolytic pathway.Jul 09, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2021 Jul 10 ;141:111905. Epub 2021 Jul 10. PMID: 34328114
Article Published Date : Jul 09, 2021
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Obesity
Pharmacological Actions : Lipolytic
[+]

Polysaccharides from dandelion root have hepatoprotective effects.Aug 24, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2017 Aug 25 ;22(9). Epub 2017 Aug 25. PMID: 28841174
Article Published Date : Aug 24, 2017
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Acetaminophen (Tylenol) Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective, Nrf2 activation
Additional Keywords : Polysaccharides
Problem Substances : Acetaminophen, Paracetamol
[+]

Protective effect of dandelion leaf water extracts on APAP-induced liver injury in rats and its mechanism.May 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2022 May 31 ;68(5):24-33. Epub 2022 May 31. PMID: 36029509
Article Published Date : May 30, 2022
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage: Drug-Induced, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Hepatoprotective, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
Problem Substances : Acetaminophen, Paracetamol
[+]

Protective effect of the polysaccharides from Taraxacum mongolicum leaf by modulating the p53 signaling pathway in H22 tumor.Oct 23, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2022 Oct 24 ;11(21). Epub 2022 Oct 24. PMID: 36359953
Article Published Date : Oct 23, 2022
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-xL down-regulation, Cell cycle arrest, Immunomodulatory
Additional Keywords : Polysaccharides
[+]

Protective effects of dandelion root extract in experimental acute on chronic liver failure.Mar 23, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2021 Mar 24 ;10(4). Epub 2021 Mar 24. PMID: 33804908
Article Published Date : Mar 23, 2021
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Liver Failure: Acute
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Protective role of the dandelion extract against the blood-liver axis, cell membranes, and anemia disorder in sodium benzoate-exposure.Oct 08, 2022

Pubmed Data : Cell Biochem Funct. 2022 Oct 9. Epub 2022 Oct 9. PMID: 36210509
Article Published Date : Oct 08, 2022
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced
Pharmacological Actions : Hepatoprotective, Renoprotective
Additional Keywords : Blood Liver Axis
Problem Substances : Sodium Benzoate
[+]

Silybum marianum and Taraxacum officinale extracts had a protective effect against oxidative kidney injuries induced by carbon tetrachloride in rats.Nov 14, 2016

Pubmed Data : Ren Fail. 2016 Nov 15:1-6. Epub 2016 Nov 15. PMID: 27845613
Article Published Date : Nov 14, 2016
Study Type : Animal Study
Additional Links
Substances : Dandelion , Milk Thistle
Diseases : Kidney Damage: Chemically-Induced, Oxidative Stress
Pharmacological Actions : Enzyme Inhibitors, Malondialdehyde Down-regulation, Renoprotective
Additional Keywords : Plant Extracts
[+]

Supplementation of pregnant and lactating rats with dandelion protects their offspring against lead poisoning.Feb 27, 2017

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2017 Feb 28 ;63(2):67-75. Epub 2017 Feb 28. PMID: 28364786
Article Published Date : Feb 27, 2017
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Lead Poisoning, Prenatal Chemical Exposures, Prenatal Nutrition: Health of the Offspring
Pharmacological Actions : Antioxidants, Hepatoprotective
Additional Keywords : Risk Reduction, Significant Treatment Outcome
Problem Substances : Lead
[+]

Synergistic antidiabetic activity of Taraxacum officinale (L.) Weber ex F.H.Wigg and Momordica charantia L. polyherbal combination.Nov 12, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2021 Nov 13 ;145:112401. Epub 2021 Nov 13. PMID: 34785415
Article Published Date : Nov 12, 2021
Study Type : Animal Study
Additional Links
Substances : Bitter Melon, Dandelion
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Alpha-amylase inhibitor, Alpha-glucosidase inhibitor
Additional Keywords : Natural Substance Synergy
[+]

T. officinale flower water syrup possesses beneficial properties by regulating prostanoids and antioxidant status.Sep 13, 2020

Pubmed Data : J Ethnopharmacol. 2020 Sep 14 ;265:113393. Epub 2020 Sep 14. PMID: 32941970
Article Published Date : Sep 13, 2020
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Obesity
Pharmacological Actions : Antioxidants
[+]

T. officinale leaf extract possesses significant anti-oxidant effects.Aug 14, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2019 Aug 15 ;8(8). Epub 2019 Aug 15. PMID: 31443195
Article Published Date : Aug 14, 2019
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
Additional Keywords : Plant Extracts
[+]

Taraxacum officinale extract ameliorates dextran sodium sulphate-induced colitis.Sep 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2019 Sep 29. Epub 2019 Sep 29. PMID: 31565850
Article Published Date : Sep 28, 2019
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Colitis, Dysbiosis
Pharmacological Actions : Gastrointestinal Agents
[+]

Taraxasterol ameliorates dextran sodium sulfate-induced murine colitis via improving intestinal barrier and modulating gut microbiota dysbiosis.Mar 24, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Biochim Biophys Sin (Shanghai). 2022 Mar 25 ;54(3):340-349. PMID: 35538040
Article Published Date : Mar 24, 2022
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Colitis
Pharmacological Actions : Gastrointestinal Agents
[+]

Taraxasterol from dandelion prevents concanavalin A-induced acute hepatic injury.Nov 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):3929-3937. PMID: 31571510
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interferon Gamma Reducer, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Concanavalin A
[+]

taraxasterol has obvious in vivo anti-inflammatory effects against animal models.Dec 31, 2016

Pubmed Data : Afr J Tradit Complement Altern Med. 2017 ;14(1):43-51. Epub 2016 Nov 23. PMID: 28480383
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Taraxasterol has the potential protective effect against Freund's complete adjuvant induced arthritis in rats.Apr 20, 2016

Pubmed Data : J Ethnopharmacol. 2016 Apr 21. Epub 2016 Apr 21. PMID: 27109342
Article Published Date : Apr 20, 2016
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Arthritis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Taraxasterol inhibits inflammation in osteoarthritis .Nov 25, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Biochim Pol. 2022 Nov 26 ;69(4):811-818. PMID: 36440749
Article Published Date : Nov 25, 2022
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Inflammation, Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
[+]

Taraxasterol mitigates Con A-induced hepatitis in mice by suppressing interleukin-2 expression and its signaling in T lymphocytes.Nov 26, 2021

Pubmed Data : Int Immunopharmacol. 2021 Nov 27:108380. Epub 2021 Nov 27. PMID: 34848154
Article Published Date : Nov 26, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, NF-kappaB Inhibitor
[+]

Taraxasterol suppresses inflammation in IL-1β-induced rheumatoid arthritis fibroblast-like synoviocytes and rheumatoid arthritis progression.Mar 05, 2019

Pubmed Data : Int Immunopharmacol. 2019 Mar 6 ;70:274-283. Epub 2019 Mar 6. PMID: 30851708
Article Published Date : Mar 05, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

These findings suggest that taraxasterol possesses the potential protective effects against ethanol-induced liver injury.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:8284107. Epub 2018 Sep 23. PMID: 30344887
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Alcohol Toxicity , Liver Damage
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, NF-kappaB Inhibitor, Nrf2 activation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

These results suggest that dandelion extracts have potential as antibacterial uropathogenic disease agents.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:2706417. Epub 2018 Jan 1. PMID: 29507587
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Escherichia coli Infections, Klebsiella Infections, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Anti-Bacterial Agents, Dandelion, Escherichia coli Infections, Klebsiella Infections, Staphylococcus aureus infection
[+]

This highlighted a potential action mechanism for the anti-inflammatory activity of dandelion in treating inflammation-related disorders.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2021 ;12:632606. Epub 2021 Feb 17. PMID: 33679781
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

This study comprehensively demonstrates the multi-target mechanisms of dandelion against triple-negative breast cancer.Feb 10, 2022

Pubmed Data : Phytomedicine. 2022 Feb 11 ;99:153986. Epub 2022 Feb 11. PMID: 35183931
Article Published Date : Feb 10, 2022
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative , Cell cycle arrest
[+]

This study suggests that T. mongolicum protects against S. aureus-infected mastitis.Nov 15, 2020

Pubmed Data : J Ethnopharmacol. 2020 Nov 16:113595. Epub 2020 Nov 16. PMID: 33212175
Article Published Date : Nov 15, 2020
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Mastitis, Staphylococcus aureus infection
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Treatment with taraxasterol significantly increased the pain thresholds and reduced the clinical arthritic scores of mice.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2016 Dec ;12(6):4035-4040. Epub 2016 Nov 2. PMID: 28101182
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Water extracts of Taraxacum coreanum Nakai acutely and chronically protected against gastritis and gastric ulcer.Jul 03, 2017

Pubmed Data : J Ethnopharmacol. 2017 Jul 4. Epub 2017 Jul 4. PMID: 28687507
Article Published Date : Jul 03, 2017
Study Type : Animal Study
Additional Links
Substances : Dandelion
Diseases : Alcohol Toxicity , Gastritis
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Gastroprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Mechanistic study on inhibition of porcine pancreatic α-amylase using the flavonoids from dandelion.Nov 11, 2020

Pubmed Data : Food Chem. 2020 Nov 12:128610. Epub 2020 Nov 12. PMID: 33221105
Article Published Date : Nov 11, 2020
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Hyperglycemia
Pharmacological Actions : Alpha-amylase inhibitor, Hypoglycemic Agents
[+]

A leaf extract of Dandelion and its main compound activated nuclear factor erythroid 2-related factor 2 and induced heme oxygenase 1.Dec 26, 2016

Pubmed Data : J Med Food. 2016 Dec 27. Epub 2016 Dec 27. PMID: 28026992
Article Published Date : Dec 26, 2016
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Heme oxygenase-1 inducer, Nrf2 activation
Additional Keywords : Antioxidants, Dandelion, Heme oxygenase-1 inducer, Nrf2 activation, oxidative stress, Plant Extracts
[+]

A methanol extract of dandelion could attenuate LPS-induced endothelial activation by inhibiting the NF-κB pathway.Nov 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Nov 29 ;17(1):508. Epub 2017 Nov 29. PMID: 29187173
Article Published Date : Nov 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Atherosclerosis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

A organic acid component from Taraxacum mongolicum can reduce LPS-induced inflammation.Aug 22, 2016

Pubmed Data : J Ethnopharmacol. 2016 Aug 23. Epub 2016 Aug 23. PMID: 27566210
Article Published Date : Aug 22, 2016
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

A water extract of dandelion exhibits anti-influenza activity. Dec 14, 2011

Pubmed Data : Virol J. 2011 Dec 14 ;8(1):538. Epub 2011 Dec 14. PMID: 22168277
Article Published Date : Dec 14, 2011
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Influenza
Pharmacological Actions : Antiviral Agents
Additional Keywords : Science Confirms Tradition, Science Confirms Traditional Chinese Medicine
[+]

Active ingredients and molecular targets of Taraxacum mongolicum against hepatocellular carcinoma.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PeerJ. 2022 ;10:e13737. Epub 2022 Jul 18. PMID: 35873910
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative
[+]

Alleviated oxidative damage by Taraxacum officinale.Jul 17, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2019 Jul 18 ;9(7). Epub 2019 Jul 18. PMID: 31323756
Article Published Date : Jul 17, 2019
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation
[+]

Ameliorative effect of dandelion peptides on benzo(a)pyrene-induced oxidative stress and inflammation in human umbilical vein endothelial cells.Aug 07, 2022

Pubmed Data : J Pept Sci. 2022 Aug 8:e3447. Epub 2022 Aug 8. PMID: 35940823
Article Published Date : Aug 07, 2022
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Benzo[a]pyrene-induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
Problem Substances : Benzo(a)pyrene
[+]

An extract of dandelion leaves potentially blocked the viral replication and NS5B gene expression in HCV infections.Aug 07, 2016

Pubmed Data : Biomed Pharmacother. 2016 Aug 8 ;83:881-891. Epub 2016 Aug 8. PMID: 27513212
Article Published Date : Aug 07, 2016
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Hepatitis C
Pharmacological Actions : Antiviral Agents
[+]

Anti-obesity attributes of Taraxacum officinale.Oct 25, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Oct 26 ;25(21). Epub 2020 Oct 26. PMID: 33114490
Article Published Date : Oct 25, 2020
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Obesity
Pharmacological Actions : Hypolipidemic
Additional Keywords : Anti-Obesity Agents
[+]

Antibiofilm activity against Staphylococcus aureus and content analysis of Taraxacum Officinale phenolic extract.May 31, 2021

Pubmed Data : Pol J Vet Sci. 2021 Jun ;24(2):243-251. PMID: 34250777
Article Published Date : May 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation
[+]

Anticancer effects of taraxacum via cell cycle arrest, necrosis, apoptosis, and endoplasmic reticulum stress.Feb 02, 2022

Pubmed Data : Am J Chin Med. 2022 Feb 3:1-19. Epub 2022 Feb 3. PMID: 35114910
Article Published Date : Feb 02, 2022
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Cervical Cancer, Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Antioxidant property of Taraxacum formosanum Kitam and its antitumor activity in non-small-cell lung cancer cells.Sep 30, 2018

Pubmed Data : Phytomedicine. 2018 Oct 1 ;49:1-10. Epub 2018 Jun 14. PMID: 30217255
Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Anti-metastatic, Antioxidants, Antiproliferative
[+]

Antioxidant sources from leaves of Russian dandelion.Jun 27, 2019

Pubmed Data : Chem Biodivers. 2019 Jun 28. Epub 2019 Jun 28. PMID: 31250533
Article Published Date : Jun 27, 2019
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Apigetrin as a natural compound might have potential for treating liver cancer.Aug 31, 2022

Pubmed Data : Cells. 2022 Sep 1 ;11(17). Epub 2022 Sep 1. PMID: 36078142
Article Published Date : Aug 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Dandelion , Flavonoids
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Assessment of effects of phenolic fractions from leaves and petals of dandelion in selected components of hemostasis.Apr 30, 2018

Pubmed Data : Food Res Int. 2018 May ;107:605-612. Epub 2018 Mar 5. PMID: 29580525
Article Published Date : Apr 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Cardiovascular Diseases
Pharmacological Actions : Anti-Platelet, Antioxidants, Cardioprotective
Additional Keywords : Plant Extracts
[+]

Bauerane inhibited the proliferation of A549 lung cancer cells in vitro and induced cell apoptosis and cell cycle arrest in a dose-dependent manner.Jan 31, 2020

Pubmed Data : Med Sci Monit. 2020 Feb 1 ;26:e919558. Epub 2020 Feb 1. PMID: 32005795
Article Published Date : Jan 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Dose Response
[+]

Botanical formulation HX109 ameliorates TP-induced benign prostate hyperplasia. Dec 06, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Dec 7 ;10(12). Epub 2018 Dec 7. PMID: 30544543
Article Published Date : Dec 06, 2018
Study Type : In Vitro Study
Additional Links
Substances : Dandelion , Lotus
Diseases : Prostatic Hyperplasia: Benign
Additional Keywords : Plant Extracts
[+]

Chemical composition, antioxidant and antiproliferative activities of Taraxacum officinale essential oil.Sep 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2022 Oct 1 ;27(19). Epub 2022 Oct 1. PMID: 36235013
Article Published Date : Sep 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Acetaminophen (Tylenol) Toxicity , Cervical Cancer
Pharmacological Actions : Antioxidants, Antiproliferative , Hepatoprotective, Malondialdehyde Down-regulation, Renoprotective, Superoxide Dismutase Up-regulation
Additional Keywords : Essential Oils
Problem Substances : Acetaminophen, Paracetamol
[+]

Chemical constituents from Taraxacum officinale have α-glucosidase inhibitory activities.Dec 07, 2017

Pubmed Data : Bioorg Med Chem Lett. 2017 Dec 8. Epub 2017 Dec 8. PMID: 29254644
Article Published Date : Dec 07, 2017
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Hypoglycemia
Pharmacological Actions : Alpha-glucosidase inhibitor
[+]

Dandelion (Taraxacum officinale) has anti-angiogenic, anti-inflammatory and anti-nociceptive (pain-killing) activities.May 01, 2008

Pubmed Data : Int J Oncol. 2008 May;32(5):1085-90. PMID: 17949929
Article Published Date : May 01, 2008
Study Type : Review
Additional Links
Substances : Dandelion
Diseases : Inflammation
Pharmacological Actions : Analgesics, Anti-Angiogenic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors
[+]

Dandelion (Taraxacum officinale) has anticancer activity against prostate and breast cancer cells.May 01, 2008

Pubmed Data : Int J Oncol. 2008 May;32(5):1085-90. PMID:18425335
Article Published Date : May 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Breast Cancer, Prostate Cancer
[+]

Dandelion (Taraxacum officinale) has potent antioxidant activity attributable to its phenolic content.Aug 01, 2005

Pubmed Data : 1: Phytomedicine. 2005 Aug;12(8):588-97. PMID: 16121519
Article Published Date : Aug 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Dandelion as a source of biologically active compounds supporting the therapy of co-existing diseases in metabolic syndrome.Sep 14, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2022 Sep 15 ;11(18). Epub 2022 Sep 15. PMID: 36140985
Article Published Date : Sep 14, 2022
Study Type : Review
Additional Links
Substances : Dandelion
Diseases : Atherosclerosis, Diabetes Mellitus: Type 2, Metabolic Syndrome X
Pharmacological Actions : Antioxidants, Hypolipidemic
[+]

Dandelion chloroform extract could be a new hypoglycemic agent for the treatment of type 2 diabetes mellitus.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:1709587. Epub 2018 Nov 7. PMID: 30524480
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
[+]

Dandelion contains compounds with antioxidant and anti-inflammatory properties. Oct 01, 2004

Pubmed Data : Mol Cell Biochem. 2004 Oct;265(1-2):107-13. PMID: 15543940
Article Published Date : Oct 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
Additional Keywords : Plant Extracts
[+]

Dandelion extract alleviated lipopolysaccharide-induced oxidative stress.Jul 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxins (Basel). 2020 Aug 1 ;12(8). Epub 2020 Aug 1. PMID: 32752301
Article Published Date : Jul 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Antioxidants, Nrf2 activation
[+]

Dandelion extract can enhance the proliferation and activity of rat skeletal muscle cells.Jul 19, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med J (Engl). 2018 Jul 20 ;131(14):1724-1731. PMID: 29998893
Article Published Date : Jul 19, 2018
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Dandelion extract inhibits lipopolysaccharide-induced oxidative stress and nitric oxide production associated with inflammation. Jan 27, 2011

Pubmed Data : J Ethnopharmacol. 2011 Jan 27;133(2):834-42. Epub 2010 Nov 11. PMID: 21075189
Article Published Date : Jan 27, 2011
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Glutathione Deficiency , Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Glutathione Upregulation , NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
[+]

Dandelion extract inhibits triple-negative breast cancer cell proliferation.Dec 31, 2021

Pubmed Data : Front Pharmacol. 2022 ;13:942996. Epub 2022 Sep 6. PMID: 36147318
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative
[+]

Dandelion extracts at the concentration could significantly inhibit both TNF-α and ICAM-1 expression.Jan 10, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Jan 11 ;17(1):38. Epub 2017 Jan 11. PMID: 28077102
Article Published Date : Jan 10, 2017
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Mastitis
Pharmacological Actions : Anti-Inflammatory Agents, Intracellular adhesion molecule-1 (ICAM-1), Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Dandelion extracts especially leaf and flower extracts are potent protective agents against UVB damage.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2015 ;2015:619560. Epub 2015 Oct 20. PMID: 26576225
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Ultraviolet Radiation Induced Damage
Pharmacological Actions : Antioxidants, Glutathione Upregulation
Additional Keywords : Plant Extracts
[+]

Dandelion extracts exhibit promising in vitro antimicrobial activity relevant for controlling fungi and gram-positive and negative bacteria.Jul 23, 2018

Pubmed Data : Phytother Res. 2018 Jul 24. Epub 2018 Jul 24. PMID: 30039597
Article Published Date : Jul 23, 2018
Study Type : Review
Additional Links
Substances : Dandelion
Diseases : Gram-Negative Bacterial Infections, Gram-Positive Bacterial Infections
Pharmacological Actions : Antimicrobial
[+]

Dandelion extracts with their antioxidant activity may be beneficial for diseases-associated with oxidative stress, and with changes of hemostasis.Jan 24, 2017

Pubmed Data : Chem Biol Interact. 2017 Jan 25 ;262:29-37. Epub 2016 Dec 5. PMID: 27923645
Article Published Date : Jan 24, 2017
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Hydrogen Peroxide Induced Toxicity, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Antioxidants, Dandelion, Hydrogen Peroxide Induced Toxicity, Lipid Peroxidation, oxidative stress, Plant Extracts
[+]

Dandelion improves the therapeutic efficiency of praziquantel in experimental Schistosomiasis.Jan 23, 2022

Pubmed Data : Acta Parasitol. 2022 Jan 24. Epub 2022 Jan 24. PMID: 35067863
Article Published Date : Jan 23, 2022
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
Additional Keywords : Natural Substance/Drug Synergy
[+]

Dandelion induces cytotoxicity in human hepatoma cells. Jan 16, 2004

Pubmed Data : Life Sci. 2004 Jan 16;74(9):1149-57. PMID: 14687655
Article Published Date : Jan 16, 2004
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Hepatoma
Pharmacological Actions : Apoptotic, Interleukin-1 alpha upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Dandelion inhibits inflammation in rat astrocytes, indicating it may have antiinflammatory activity in the central nervous system. Aug 01, 2000

Pubmed Data : Immunopharmacol Immunotoxicol. 2000 Aug;22(3):519-30. PMID: 10946829
Article Published Date : Aug 01, 2000
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Brain: Microglial Activation, Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Interleukin-1 alpha downregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Dandelion leaves have an anti-inflammatory effect on lipopolysaccharide-induced inflammation. Aug 01, 2010

Pubmed Data : J Med Food. 2010 Aug;13(4):870-8. PMID: 20673058
Article Published Date : Aug 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation
Additional Keywords : Plant Extracts
[+]

Dandelion may serve as a promising therapeutic strategy for TNBC by modulating tumor immune microenvironment.Mar 10, 2021

Pubmed Data : J Ethnopharmacol. 2021 Mar 11 ;274:113978. Epub 2021 Mar 11. PMID: 33716082
Article Published Date : Mar 10, 2021
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative , Immunomodulatory, Interleukin-10 downregulation
Additional Keywords : Tumor Microenvironment
[+]

Dandelion polysaccharide is a promising anti-cancer drug candidate for treating liver cancer.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:460. Epub 2020 Apr 8. PMID: 32322211
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Liver Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Vascular Endothelial Growth Factor Inhibitors
Additional Keywords : Polysaccharides
[+]

Dandelion Root Extract effectively induces apoptosis in highly aggressive and resistant Chronic Myelomonocytic Leukemia (CMML) cell linesJan 01, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2012 ;7(2):e30604. Epub 2012 Feb 17. PMID: 22363452
Article Published Date : Jan 01, 2012
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Leukemia, Leukemia: Multi-Drug Resistant
Pharmacological Actions : Apoptotic, Autophagy Up-regulation, Caspase-3 Activation, Caspase-8 activation
Additional Keywords : Chronic Myelomonocytic Leukemia, Dose Response, Selective Cytotoxicity
[+]

Dandelion root extract suppressed gastric cancer cells proliferation and migration.Jul 13, 2017

Pubmed Data : Biomed Pharmacother. 2017 Jul 14 ;93:1010-1017. Epub 2017 Jul 14. PMID: 28724210
Article Published Date : Jul 13, 2017
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Gastric Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative
Additional Keywords : Plant Extracts
[+]

Dandelion root has a potent action against chemoresistant melanoma without toxicity to healthy cells.Jan 01, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2011 ;2011:129045. Epub 2010 Dec 30. PMID: 21234313
Article Published Date : Jan 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Cancers: Drug Resistant, Melanoma
Pharmacological Actions : Apoptotic, Chemosensitizer
Additional Keywords : Chemoresistance, Selective Cytotoxicity
[+]

Dandelion roots are a safe and valuable source of different class natural compounds possessing antioxidant, anticoagulant and anti-platelet activities.Feb 20, 2019

Pubmed Data : Food Chem Toxicol. 2019 Feb 21. Epub 2019 Feb 21. PMID: 30797873
Article Published Date : Feb 20, 2019
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Pharmacological Actions : Anti-Platelet, Anticoagulants, Antioxidants
[+]

Dandelion seed extract affects tumor progression and enhances the sensitivity of cisplatin in esophageal squamous cell carcinoma.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:897465. Epub 2022 May 20. PMID: 35668940
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Squamous cell carcinoma
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

Dandelion seeds exhibit antifungal activity. Nov 01, 2009

Pubmed Data : Protein Pept Lett. 2009 Nov 1. Epub 2009 Nov 1. PMID: 19594427
Article Published Date : Nov 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Fungal Infection
Pharmacological Actions : Antifungal Agents
[+]

Effect of dandelion extracts on the proliferation of ovarian granulosa cells and expression of hormone receptors.Jul 19, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med J (Engl). 2018 Jul 20 ;131(14):1694-1701. PMID: 29998889
Article Published Date : Jul 19, 2018
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Endocrine Diseases, Endocrine Imbalances
[+]

Exploration and validation of Taraxacum mongolicum anti-cancer effect.Jul 05, 2022

Pubmed Data : Comput Biol Med. 2022 Jul 6 ;148:105819. Epub 2022 Jul 6. PMID: 35810695
Article Published Date : Jul 05, 2022
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Cancers: All
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Extraction and identification of new flavonoid compounds in dandelion Taraxacum mongolicum Hand.-Mazz. with evaluation of antioxidant activities.Feb 06, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2023 Feb 7 ;13(1):2166. Epub 2023 Feb 7. PMID: 36750602
Article Published Date : Feb 06, 2023
Study Type : Review
Additional Links
Substances : Dandelion , Flavonoids
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Extraction and isolation of the active ingredients of dandelion and its antifungal activity against Candida albicans.Nov 05, 2019

Pubmed Data : Mol Med Rep. 2019 Nov 6. Epub 2019 Nov 6. PMID: 31746416
Article Published Date : Nov 05, 2019
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Candida Albicans
Pharmacological Actions : Antimicrobial
[+]

Flavonoid preparations from Taraxacum officinale a phytochemical, antioxidant and hemostasis study.Nov 17, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Nov 18 ;25(22). Epub 2020 Nov 18. PMID: 33218202
Article Published Date : Nov 17, 2020
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Cardiovascular Diseases
Pharmacological Actions : Antioxidants
[+]

Heavy metals induce antibiotic resistance and dandelion root extracts and taraxasterol could be used to help reverse bacterial resistance to antibiotics.Jun 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Microbiol. 2020 Jun 30. Epub 2020 Jun 30. PMID: 32602832
Article Published Date : Jun 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Heavy Metal Toxicity
Additional Keywords : Antibiotic Resistance, Plant Extracts
Problem Substances : Heavy Metals
[+]

hese findings suggest that the potent anti-inflammatory activity of T. officinale, possibly through the regulation of Nrf2/HO-1 and NF-κB signaling pathway.Mar 04, 2020

Pubmed Data : Am J Chin Med. 2020 Mar 5:1-18. Epub 2020 Mar 5. PMID: 32138531
Article Published Date : Mar 04, 2020
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Nrf2 activation
[+]

In vitro effect of Taraxacum officinale leaf aqueous extract on the interaction between ACE2 cell surface receptor and SARS-CoV-2 spike protein D614 and four mutants.Oct 16, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2021 Oct 17 ;14(10). Epub 2021 Oct 17. PMID: 34681279
Article Published Date : Oct 16, 2021
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Coronavirus Infection
Pharmacological Actions : Antiviral Agents
Additional Keywords : SARS-CoV-2 Spike Protein
[+]

In vitro inhibition effects of hepatitis B virus by dandelion and taraxasterolDec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Infect Agent Cancer. 2020 ;15:44. Epub 2020 Jul 6. PMID: 32647534
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Hepatitis B
Pharmacological Actions : Antiviral Agents
[+]

Lemon balm and dandelion leaf extract synergistically alleviate ethanol-induced hepatotoxicity.Jun 03, 2020

Pubmed Data : J Food Biochem. 2020 Jun 4:e13232. Epub 2020 Jun 4. PMID: 32497278
Article Published Date : Jun 03, 2020
Study Type : In Vitro Study
Additional Links
Substances : Dandelion , Lemon Balm
Diseases : Alcoholic Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
Additional Keywords : Natural Substance Synergy
[+]

Luteolin and chicoric acid, two abundant constituents of the common dandelion inhibit lipopolysaccharide-induced toxicity. Apr 15, 2011

Pubmed Data : Eur J Pharmacol. 2011 Apr 15. Epub 2011 Apr 15. PMID: 21513709
Article Published Date : Apr 15, 2011
Study Type : In Vitro Study
Additional Links
Substances : Chicoric Acid, Dandelion , Luteolin
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor
[+]

Nano-dandelion had good cellular penetration and tumor cytotoxicity.Nov 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Deliv. 2019 Dec ;26(1):1265-1279. PMID: 31777307
Article Published Date : Nov 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Cytotoxic
[+]

Nematicidal potential of Taraxacum officinale.Aug 08, 2018

Pubmed Data : Environ Sci Pollut Res Int. 2018 Aug 9. Epub 2018 Aug 9. PMID: 30094666
Article Published Date : Aug 08, 2018
Study Type : In Vitro Study
Additional Links
Substances : Dandelion , Tomato
Pharmacological Actions : Antiparasitic Agents
[+]

Nettle, dandelion, mistletoe and especially myrtle inhibit the enzyme alpha-glucosidase, which may have therapeutic value in diabetes type 2. Jan 01, 2005

Pubmed Data : Prep Biochem Biotechnol. 2005;35(1):29-36. PMID: 15704495
Article Published Date : Jan 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Dandelion , Mistletoe, Myrtle, Nettle
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Alpha-glucosidase inhibitor , Hypoglycemic Agents
Additional Keywords : Plant Extracts
[+]

New perspectives on the effect of dandelion, its food products and other preparations on the cardiovascular system and its diseases.Mar 23, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Mar 24 ;14(7). Epub 2022 Mar 24. PMID: 35405963
Article Published Date : Mar 23, 2022
Study Type : Review
Additional Links
Substances : Dandelion
Diseases : Cardiovascular Diseases
Pharmacological Actions : Antioxidants, Cardioprotective
Additional Keywords : Plant Extracts
[+]

Polysaccharide extracted from Taraxacum platycarpum root exerts immunomodulatory activity via MAPK and NF-κB pathways in RAW264.7 cells.Aug 11, 2021

Pubmed Data : J Ethnopharmacol. 2021 Aug 12 ;281:114519. Epub 2021 Aug 12. PMID: 34390795
Article Published Date : Aug 11, 2021
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Pharmacological Actions : Immunomodulatory, Immunostimulatory
Additional Keywords : Polysaccharides
[+]

Polysaccharides from dandelion (Taraxacum mongolicum) leaves: Insights into innovative drying techniques on their structural characteristics and biological activities.Nov 10, 2020

Pubmed Data : Int J Biol Macromol. 2020 Nov 11. Epub 2020 Nov 11. PMID: 33188812
Article Published Date : Nov 10, 2020
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Advanced Glycation End products (AGE), Hyperglycemia
Pharmacological Actions : Alpha-glucosidase inhibitor , Anti-Glycation Agents, Antioxidants, Hypnotics and Sedatives
Additional Keywords : Polysaccharides
[+]

Potential Epha2 receptor blockers involved in cerebral malaria. Nov 03, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pathogens. 2022 Nov 4 ;11(11). Epub 2022 Nov 4. PMID: 36365047
Article Published Date : Nov 03, 2022
Study Type : In Vitro Study
Additional Links
Substances : Basil, Dandelion , Guduchi , Rosemary
Diseases : Malaria
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Protective effect of taraxasterol on ischemia/reperfusion-induced acute kidney injury.Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int Immunopharmacol. 2020 Dec ;89(Pt A):107169. Epub 2020 Nov 10. PMID: 33183976
Article Published Date : Nov 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Ischemia, Kidney Damage
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Renoprotective
[+]

Reparative effects of dandelion fermentation broth on UVB-induced skin inflammation.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Cosmet Investig Dermatol. 2022 ;15:471-482. Epub 2022 Mar 15. PMID: 35313537
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Dandelion , Fermented Foods and Beverages
Diseases : Inflammation, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation
[+]

Research on the mechanisms of taraxerol for the treatment of gastric cancer effect based on network pharmacology.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Immunopathol Pharmacol. 2022 Jan-Dec;36:20587384211063962. PMID: 34986036
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Gastric Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Results suggest that a dandelion polysaccharide possesses efficacious antioxidant and hypoglycemic properties.Apr 14, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Apr 15 ;24(8). Epub 2019 Apr 15. PMID: 30991766
Article Published Date : Apr 14, 2019
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Hyperglycemia, Oxidative Stress
Pharmacological Actions : Alpha-amylase inhibitor, Alpha-glucosidase inhibitor , Antioxidants, Hypoglycemic Agents
Additional Keywords : Polysaccharides
[+]

Revealing the metabolic mechanism of dandelion extract against A549 cells using UPLC-QTOF MS.Nov 01, 2021

Pubmed Data : Biomed Chromatogr. 2021 Nov 2:e5272. Epub 2021 Nov 2. PMID: 34727378
Article Published Date : Nov 01, 2021
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative
[+]

Review: the phytochemical and pharmacological profile of dandelion (Taraxacum). Oct 11, 2006

Pubmed Data : J Ethnopharmacol. 2006 Oct 11;107(3):313-23. Epub 2006 Jul 22. PMID: 16950583
Article Published Date : Oct 11, 2006
Study Type : Review
Additional Links
Substances : Dandelion
Pharmacological Actions : Analgesics, Anti-Allergic Agents, Anti-Inflammatory Agents, Anticarcinogenic Agents, Antioxidants, Cholagogues and Choleretics, Diuretics, Hypoglycemic Agents
Additional Keywords : Plant Extracts
[+]

Steroidogenic effects of Taraxacum officinale extract on the levels of steroidogenic enzymes in mouse Leydig cells.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anim Cells Syst (Seoul). 2018 ;22(6):407-414. Epub 2018 Nov 8. PMID: 30533263
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Hypogonadism
Pharmacological Actions : Enzyme Inhibitors, MicroRNA modulator
[+]

T. coreanum exhibits a promising function in preventionof neurodegeneration.Mar 31, 2017

Pubmed Data : Mol Med Rep. 2017 Apr ;15(4):2347-2352. Epub 2017 Feb 22. PMID: 28260050
Article Published Date : Mar 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
[+]

T. coreanum has potential use as a cost-effective phytopharmaceutical in complementary therapy against type-2 diabetes and its complications.Aug 26, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Aug 27 ;23(9). Epub 2018 Aug 27. PMID: 30150550
Article Published Date : Aug 26, 2018
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Advanced Glycation End products (AGE), Diabetes Mellitus: Type 2
Pharmacological Actions : Alpha-glucosidase inhibitor , Anti-Glycation Agents
[+]

T. mongolicum showed cytotoxicity against all three tested breast cancer cell lines in this study.Oct 06, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Oct 7 ;23(19). Epub 2022 Oct 7. PMID: 36233219
Article Published Date : Oct 06, 2022
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Apoptotic
[+]

Taraxacum officinale and Urtica dioica extracts inhibit dengue virus serotype 2 replication in vitroMar 15, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2018 Mar 16 ;18(1):95. Epub 2018 Mar 16. PMID: 29548293
Article Published Date : Mar 15, 2018
Study Type : In Vitro Study
Additional Links
Substances : Dandelion , Nettle
Diseases : Dengue
Pharmacological Actions : Antiviral Agents
[+]

Taraxacum officinale extract shows antitumor effects on pediatric cancer cells and enhances mistletoe therapy.Sep 30, 2018

Pubmed Data : Complement Ther Med. 2018 Oct ;40:158-164. Epub 2018 Mar 13. PMID: 30219442
Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Dandelion , Mistletoe
Diseases : Neuroblastoma
Pharmacological Actions : Anti-metastatic, Apoptotic
Additional Keywords : Natural Substance Synergy
[+]

Taraxacum officinale F.H. was found to be a novel TRAIL sensitizer for cancer therapy.Feb 02, 2015

Pubmed Data : Mol Carcinog. 2015 Feb 3. Epub 2015 Feb 3. PMID: 25647515
Article Published Date : Feb 02, 2015
Study Type : In Vitro Study
Additional Links
Substances : Chicoric Acid, Dandelion
Diseases : Liver Cancer
Pharmacological Actions : TRAIL sensitizer
[+]

Taraxacum officinale fruit extract has a protective effect against cellular death induced by sodium nitroprusside.Apr 06, 2012

Pubmed Data : Pharm Biol. 2012 Apr 6. Epub 2012 Apr 6. PMID: 22480378
Article Published Date : Apr 06, 2012
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
Problem Substances : Nitroprusside
[+]

Taraxasterol acetate targets RNF31 to inhibit RNF31/p53 axis-driven cell proliferation in colorectal cancer.Apr 05, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Death Discov. 2021 Apr 6 ;7(1):66. Epub 2021 Apr 6. PMID: 33824292
Article Published Date : Apr 05, 2021
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative
[+]

Taraxasterol attenuates melanoma progression via inactivation of reactive oxygen species-mediated PI3K/Akt signaling pathway.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Hum Exp Toxicol. 2022 Jan-Dec;41:9603271211069034. PMID: 35128947
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Melanoma
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
[+]

Taraxasterol could alleviate deoxynivalenol-induced damage to MAC-T cells.Jan 14, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxins (Basel). 2022 03 15 ;14(3). Epub 2022 Mar 15. PMID: 35324708
Article Published Date : Jan 14, 2022
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Mycotoxin Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants
Problem Substances : Mycotoxin
[+]

Taraxasterol had protective effects against cigarette smoke induced lung inflammation.Jul 27, 2016

Pubmed Data : Eur J Pharmacol. 2016 Jul 28. Epub 2016 Jul 28. PMID: 27477353
Article Published Date : Jul 27, 2016
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Inflammation, Lung Injury: Smoke-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Taraxasterol inhibited vascular inflammation through activating LXRα.Sep 30, 2018

Pubmed Data : Inflammation. 2018 Oct ;41(5):1755-1761. PMID: 29951871
Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-8 downregulation, NF-kappaB Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Taraxasterol inhibits TGF-β1-induced epithelial-to-mesenchymal transition in papillary thyroid cancer cells.Jul 04, 2021

Pubmed Data : Hum Exp Toxicol. 2021 Jul 5:9603271211023792. Epub 2021 Jul 5. PMID: 34219514
Article Published Date : Jul 04, 2021
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Thyroid Cancer
Pharmacological Actions : Anti-metastatic, Transforming growth factor beta (TGF-β) inhibitor, Wnt/β-catenin signaling pathway modulation
[+]

Taraxasterol may be a useful agent for prevention and treatment of osteoarthritis.Jun 04, 2015

Pubmed Data : Eur J Pharmacol. 2015 Jun 5 ;756:38-42. Epub 2015 Mar 20. PMID: 25797286
Article Published Date : Jun 04, 2015
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Matrix metalloproteinase-1 (MMP-1) inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation
[+]

Taraxasterol protects hippocampal neurons from oxygen-glucose deprivation-induced injury.Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Artif Cells Nanomed Biotechnol. 2020 Dec ;48(1):252-258. PMID: 31851841
Article Published Date : Nov 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Brain: Oxidative Stress, Cerebral Ischemia
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

Taraxasterol suppresses cell proliferation and boosts cell apoptosis via inhibiting GPD2-mediated glycolysis in gastric cancer.Nov 30, 2021

Pubmed Data : Cytotechnology. 2021 Dec ;73(6):815-825. Epub 2021 Oct 18. PMID: 34776631
Article Published Date : Nov 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Gastric Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Taraxasterol suppresses the growth of human liver cancer by upregulating Hint1 expression.Jun 30, 2018

Pubmed Data : J Mol Med (Berl). 2018 Jul ;96(7):661-672. Epub 2018 May 27. PMID: 29806073
Article Published Date : Jun 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

The antimicrobial efficacy of dandelion root extracts in this study support the use of dandelion root as a source of natural antimicrobial compounds.Jan 20, 2015

Pubmed Data : Phytother Res. 2015 Jan 21. Epub 2015 Jan 21. PMID: 25644491
Article Published Date : Jan 20, 2015
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Bacillus Cereus infection, Staphylococcus aureus: Methicillin-resistant (MRSA), Staphylococcus aureus infection
Pharmacological Actions : Antimicrobial
Additional Keywords : Plant Extracts
[+]

The current observations clearly demonstrated the potency of methanolic extracts of dandelion root against liver cancer.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:875. Epub 2017 Nov 28. PMID: 29234282
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Plant Extracts
[+]

The potential of dandelion in the fight against gastrointestinal diseases.Apr 07, 2022

Pubmed Data : J Ethnopharmacol. 2022 Apr 8:115272. Epub 2022 Apr 8. PMID: 35405251
Article Published Date : Apr 07, 2022
Study Type : Review
Additional Links
Substances : Dandelion
Diseases : Gastrointestinal Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Gastrointestinal Agents
[+]

These findings support dandelion extract might be a potential therapeutic approach to treat triple-negative breast cancer.Apr 27, 2017

Pubmed Data : J Ethnopharmacol. 2017 Apr 28. Epub 2017 Apr 28. PMID: 28461119
Article Published Date : Apr 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Apoptotic, Cell cycle arrest, MicroRNA modulator
Additional Keywords : Gene Expression Regulation, Plant Extracts
[+]

These results suggested that taraxasterol inhibits LPS-induced inflammatory response in BV2 microglia cells.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:278. Epub 2018 Apr 4. PMID: 29670526
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

This research indicated that taraxasterol and dandelion extract has anti-crystallization activities.Oct 31, 2018

Pubmed Data : Ren Fail. 2018 Nov ;40(1):298-305. PMID: 29619876
Article Published Date : Oct 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Kidney Stones
[+]

This review recapitulates previous work on dandelion and its potential for the treatment and prevention of T2D.May 31, 2016

Pubmed Data : Rev Diabet Stud. 2016 Summer-Fall;13(2-3):113-131. Epub 2016 Aug 10. PMID: 28012278
Article Published Date : May 31, 2016
Study Type : Review
Additional Links
Substances : Dandelion
Diseases : Diabetes Mellitus: Type 2, Diabetes Mellitus: Type 2: Prevention
Additional Keywords : Dandelion, Diabetes mellitus: Type 2, Diabetes Mellitus: Type 2: Prevention, Risk Reduction
[+]

This study supports the idea that Taraxacum officinale Wigg. is a promising agent for preventing neurodegenerative diseases.Jul 18, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Jul 19 ;10(7). Epub 2018 Jul 19. PMID: 30029533
Article Published Date : Jul 18, 2018
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Antioxidants, Heme oxygenase-1 inducer, Neuroprotective Agents, Nrf2 activation
Additional Keywords : Plant Extracts
[+]

Total flavonoids of Taraxacum mongolicum inhibit non-small cell lung cancer by regulating immune function.Aug 08, 2021

Pubmed Data : J Ethnopharmacol. 2021 Aug 9 ;281:114514. Epub 2021 Aug 9. PMID: 34384846
Article Published Date : Aug 08, 2021
Study Type : In Vitro Study
Additional Links
Substances : Dandelion , Flavonoids
Diseases : Non-Small-Cell Lung Carcinoma
Pharmacological Actions : Antiproliferative , Immunomodulatory
[+]

Various herbs may have a therapeutic role in preventing and treating kidney and bladder stone formation. Jan 01, 1994

Pubmed Data : Int Urol Nephrol. 1994;26(5):507-11. PMID: 7860196
Article Published Date : Jan 01, 1994
Study Type : Review
Additional Links
Substances : Burdock, Dandelion , Horsetail, Lithospermum officinale, Silene saxifraga, Uva Ursi (aka Bearberry), Verbena officinalis
Diseases : Bladder Stones, Kidney Stones, Urolithiasis

Copyright: marilyna / 123RF Stock Photo

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