Toggle navigation
Research Tools
Research Dashboard
Search Abstracts
Search Articles
Search All Content (Google)
Topic Research Discovery
Diseases
Therapeutic Substances
Therapeutic Actions
Pharmacological Actions
Problem Substances
Problematic Actions
Adverse Pharmacological Actions
Trending Topics
Smart Search - Evidence Generator
Smart Search: Diseases
Smart Search: Therapeutic Substances
Smart Search: Pharmacological Actions
Articles
Most Recent
Most Popular
Find Articles
My Membership
Memberships
Compare Membership Plans
Join our Free Newsletter
Log in
or
Join us
x
This is a member's only feature.
Please
join or upgrade
x
This is a member's only feature.
Please
join or upgrade
Delta-tetrahydrocannabinol (THC)
Views 3467
Jump to
Abstracts
Focused Research Topics
Focus Your Research
Click any topic below to filter + focus research
328 Diseases Researched for Delta-tetrahydrocannabinol (THC)
Name
AC
CK
Focus
Multiple Sclerosis
46
318
Epilepsy
44
200
Neuropathic Pain
18
128
Anxiety
23
100
Inflammation
50
95
Tourette Syndrome
8
75
Parkinson's Disease
22
73
Cancers: All
43
68
Dravet syndrome
8
64
Inflammatory Bowel Diseases
13
59
Pain
8
57
Epilepsy: Childhood
6
56
Autism Spectrum Disorders
9
54
Morphine Tolerance/Dependence
6
50
Seizures
9
45
Glioma
21
44
Chronic Pain
13
43
Stroke
4
43
Glioblastoma Multiforme
12
40
Huntington Disease
10
40
Opioid Tolerance/Dependence
1
40
Stroke: Attenuation/Recovery
6
39
Neurodegenerative Diseases
24
38
Alzheimer's Disease
26
37
Spinal Cord Injuries
5
35
Breast Cancer
21
32
Muscle Spasticity
3
32
Depression
16
31
Diabetes Mellitus: Type 2
7
31
Brachial Plexus Neuropathies
2
30
Brain Inflammation
20
30
Anxiety Disorders
8
29
Schizophrenia
15
29
Oxidative Stress
14
28
Sleep Disorders
5
27
Lennox-Gastaut Syndrome
6
25
Amyotrophic lateral sclerosis (ALS)
4
24
Post-Traumatic Stress Disorders (PTSD)
9
24
Psychoses
6
24
Insomnia
3
23
Lipopolysaccharide-Induced Toxicity
13
23
Obsessive-Compulsive Disorder
4
23
Bladder Dysfunction
2
22
Lung Cancer
12
22
Marijuana Addiction/Withdrawal
3
22
Memory Disorders
5
22
Cancer Metastasis
11
21
Dementia
6
20
Fibromyalgia
2
20
Hypoglycemia
1
20
Overactive Bladder
1
20
Peripheral Nerve Diseases
1
20
Stroke: Ischemic
4
19
Brain Cancer
4
18
Glioblastoma
10
18
Nonalcoholic fatty liver disease (NAFLD)
4
18
Colitis
7
17
HIV Infections
5
17
Hyperalgesia
7
17
Cancer: Pain
5
16
Diabetic Neuropathies
3
16
Acne
2
15
Brain Ischemia
7
15
Ulcerative Colitis
2
15
Brain Injury: Traumatic
3
14
Brain: Microglial Activation
6
14
Astrocytoma
4
13
Brain Damage: Hypoxic Ischemic Insult
6
13
Chemotherapy-Induced Toxicity: Cisplatin
4
13
Encephalopathy
2
13
Cerebral Ischemia
5
12
Colon Cancer
8
12
Epileptic Seizures
2
12
Hypertension
2
12
Prostate Cancer
10
12
Amyotrophic Lateral Sclerosis
7
11
Endocannabinoid Disorders
2
11
Ovarian Cancer
2
11
Skin Cancer
5
11
Anorexia: Dementia-Associated
1
10
Attention Deficit Hyperactivity Disorder
1
10
Autoimmune Diseases
7
10
Cardiovascular Diseases
4
10
Child Behavior Disorders
1
10
Cocaine Addiction
1
10
Cognitive Decline/Dysfunction
5
10
Colorectal Cancer
7
10
Crack Addiction/Withdrawal
1
10
Delirium: Drug-Induced
1
10
Diabetic Complications
6
10
Dry Skin
1
10
Glaucoma
4
10
Impairment: Driving Related
1
10
Incontinence
1
10
Learning disorders
1
10
Nausea: Pregnancy-Associated
1
10
Neurogenic Bladder
1
10
Neuropathic Pain: HIV-associated
1
10
Neuropathy: HIV associated
1
10
Obesity
5
10
Organ Transplantation: Kidney
1
10
Pancreatitis: Chronic
1
10
Phantom Limb
1
10
Quality of Life: Poor
1
10
Social Anxiety Disorder (SAD)
1
10
Stress
1
10
Sturge-Weber Syndrome
1
10
Temporal Lobe Epilepsy (TLE)
1
10
Tuberous Sclerosis
1
10
Vaccine-induced Toxicity
1
10
Allodynia
5
9
Breast Cancer: Triple Negative
6
9
Lymphoma
4
9
Melanoma
5
9
Psychiatric Disorders
7
9
Endocannabinoid System
7
8
Middle Cerebral Artery Occlusion (MCAO)
4
8
Myocardial Infarction
3
8
Myocardial Ischemia
3
8
Traumatic Memory Formation
4
8
Aging: Brain
3
6
Astrocytoma: Grade IV
1
6
Brain: Oxidative Stress
3
6
Chemotherapy-Induced Toxicity: Doxorubicin
4
6
Coronavirus Infection
6
6
Diabetes Mellitus: Type 1
3
6
Emesis
1
6
Epidermolysis Bullosa
1
6
Osteoarthritis
5
6
Pancreatic Cancer
6
6
Vomiting
1
6
Acute Myeloid Leukemia
2
5
Alcohol Toxicity
3
5
Alcoholic Liver Disease
1
5
Asthma
3
5
Cachexia
3
5
Chemotherapy and Radiation Toxicity
2
5
Chemotherapy-Induced Toxicity: Paclitaxel
2
5
Cholangiocarcinoma
1
5
Diabetes Mellitus: Type 1: Prevention
3
5
Drug Abuse
3
5
Gastrointestinal Inflammation
2
5
Gliomas
3
5
Leukemia
4
5
Neuroblastoma
2
5
Psychiatric Disorder: Conditioned Fear
3
5
Psychotic Disorders
4
5
Acute Respiratory Distress Syndrome
2
4
Arteriosclerosis
1
4
Arthritis
3
4
Bladder Cancer
3
4
Brain Damage
3
4
Chemotherapy-Induced Nausea
3
4
Chemotherapy-Induced Toxicity: Oxaliplatin
1
4
Chemotherapy-Induced Toxicity: Vincristine
1
4
Cocaine Toxicity
2
4
Colon Cancer: Prevention
2
4
Dermatitis
1
4
Diabetes: Cataract
2
4
Endothelial Dysfunction
2
4
Endotoxemia
2
4
Eye Damage
1
4
Febrile Seizures
2
4
High Fat Diet
2
4
Hypersensitivity
2
4
Iron Overload
2
4
Ischemia
2
4
Liver Cancer
3
4
Metabolic Syndrome X
1
4
Psoriasis
4
4
Rhabdomyosarcoma
1
4
Thyroid Cancer
3
4
Acute T cell Leukemias
2
3
Acute lymphoblastic leukemia (ALL)
2
3
Aging
2
3
Allergic Airway Diseases
2
3
Attention Deficit Disorder with Hyperactivity
1
3
Autism
2
3
Bipolar Disorder
1
3
Cachexia: Cancer
3
3
Drug Addiction
2
3
Encephalomyelitis
2
3
Endometrial Cancer
1
3
Epilepsy: Infant
1
3
Epilepsy: Malignant Migrating Partial Seizures
1
3
Fibrosis
2
3
Gastric Cancer
3
3
Gastrointestinal Diseases
2
3
Immune Disorders
2
3
Liver Fibrosis
2
3
Multiple Myeloma
2
3
Neurologic Disorders
2
3
Oral Mucositis
2
3
Staphylococcus aureus infection
2
3
Tremor
2
3
Alcohol Addiction
2
2
Alcohol Withdrawal
1
2
Amphetamine Addiction/Withdrawal
1
2
Angelman Syndrome
1
2
Animal Diseases: Simian Immunodeficiency Virus (SIV)
1
2
Appetite Disorders: Loss/Lack of
1
2
Atopic Dermatitis
1
2
Bone Fractures
1
2
Brain Edema
1
2
Breast Cancer: Lung Metastasis
1
2
Breast Cancer: Metastatic
1
2
Breast Cancer: Prevention
1
2
Cachexia: Chemotherapy Induced
1
2
Cancers: Drug Resistant
2
2
Carcinoma: Non-Small-Cell Lung
1
2
Cardiac Arrhythmias
1
2
Cardiomyopathy
1
2
Cerebral Hypoperfusion
1
2
Chemotherapy-Induced Toxicity: 5-fluorouracil
1
2
Cocaine Withdrawal
1
2
Cough
1
2
Degenerative Disk Disease
1
2
Depression
1
2
Depressive Disorder
1
2
Dermatitis: Contact
1
2
Diabetes: Cardiovascular Illness
1
2
Diabetes: Memory Problems
1
2
Diabetes: Oxidative Stress
1
2
Diabetic Neuropathy
1
2
Diabetic Retinopathy
1
2
Drug-Induced Toxicity: Epilepsy Drugs
1
2
Epilepsy: Drug-Induced
1
2
Fatty Liver
1
2
Friedreich Ataxia
1
2
Fulminant Hepatic Failure
1
2
Gastroschisis
1
2
Head and Neck Cancer
1
2
Headache
2
2
Heart Attack
1
2
Hepatic Encephalopathy
1
2
Hepatitis C
2
2
Hydrogen Peroxide Induced Toxicity
2
2
Hypersensitivity: Type IV
1
2
Hypertension: Pulmonary
1
2
Hypothermia
1
2
Immune Dysregulation: TH1/TH2 imbalance
1
2
Infant Neurological Development
1
2
Inflammation: Neutrophil-Mediated
1
2
Insulin Resistance
1
2
Interstitial Lung Diseases
1
2
Liver Damage
1
2
Liver Disease
1
2
Liver Failure: Acute
1
2
Liver Injury: Ischemia/reperfusion
1
2
Lung Inflammation
1
2
Malaria
1
2
Memory Disorders: Drug-Induced
1
2
Metabolic Diseases
1
2
Mitochondrial Dysfunction
1
2
Mood Disorders
1
2
Muscle Soreness
1
2
Myocarditis: Autoimmune
1
2
Neonatal Stroke
1
2
Neuralgia
1
2
Oral Cancer
1
2
Osteoporosis
2
2
Periodontitis
1
2
Prion Diseases
1
2
Sciatic Nerve Crush Injury
1
2
Sepsis
1
2
Skin Diseases: Inflammatory
1
2
Spinal Cord Inflammation
1
2
Staphylococcus aureus: Methicillin-resistant (MRSA)
2
2
Tardive Dyskinesia
1
2
Traumatic Brain Injury
1
2
Ultraviolet Radiation Induced Damage
2
2
Urinary Bladder Diseases
1
2
Uveitis
1
2
AIDS
1
1
Acetaminophen (Tylenol) Toxicity
1
1
Acquired Immunodeficiency Syndrome
1
1
Allergies
1
1
Anorexia
1
1
Appetite Disorders
1
1
Arrhythmias: Cardiac
1
1
Arthritis: Rheumatoid
1
1
Atherosclerosis
1
1
Bone Diseases
1
1
Bronchial Diseases
1
1
Burkitt Lymphoma
1
1
Cadmium Poisoning
1
1
Cancers: Multi-Drug Resistant
1
1
Candida Albicans
1
1
Candida Infection
1
1
Central Nervous System Diseases
1
1
Cervical Cancer
1
1
Cirrhosis
1
1
Clostridium Infections
1
1
Diabetes: Cognitive Dysfunction
1
1
Dry Eye Syndromes
1
1
Dystonia
1
1
Ebola Virus Infections
1
1
Eczema
1
1
Escherichia coli Infections
1
1
Eye Diseases
1
1
Gram-Positive Bacterial Infections
1
1
Hepatitis
1
1
Hepatitis: Autoimmune
1
1
Herpes Simplex Virus Type 2
1
1
Herpes: Kaposi-Associated
1
1
Influenza
1
1
Intestinal Permeability
1
1
Irritable Bowel Syndrome
1
1
Kaposi Disease
1
1
Kidney Cancer
1
1
Kidney Damage
1
1
Leishmaniasis
1
1
Leukemia: T-cell acute Lymphoblastic
1
1
Lung Injury: Acute
1
1
Methicillin-resistant Staphylococcus aureus
1
1
Movement Disorders
1
1
Nausea: Chemotherapy-Induced
1
1
Neurological Conditions
1
1
Peripheral Neuropathies
1
1
Prostate: PSA Doubling
1
1
Pruritus
1
1
Pseudomonas aeruginosa
1
1
Rheumatoid Arthritis
1
1
Skin Diseases
1
1
Testicular Cancer
1
1
Tobacco Addiction/Withdrawal
1
1
Tumors
1
1
Wound Healing
1
1
124 Pharmacological Actions Researched for Delta-tetrahydrocannabinol (THC)
Name
AC
CK
Focus
Neuroprotective Agents
145
369
Anti-Inflammatory Agents
130
310
Anticonvulsants
52
283
Analgesics
45
225
Apoptotic
86
154
Antiproliferative
72
140
Anti-Anxiety Agents
30
124
Antioxidants
37
60
Antidepressive Agents
20
58
Immunomodulatory
28
54
Tumor Necrosis Factor (TNF) Alpha Inhibitor
24
49
Anti-metastatic
24
47
Angiogenesis Inhibitors
15
44
Antineoplastic Agents
26
38
Antinoceceptive
12
34
Vasodilator Agents
5
31
Chemotherapeutic
21
30
Hypoglycemic Agents
3
24
Anti-Apoptotic
12
23
Cyclooxygenase 2 Inhibitors
7
23
Antispasmodic
2
22
Autophagy Up-regulation
10
22
Vascular Endothelial Growth Factor Inhibitors
3
22
Immunosuppressive Agents
8
21
Chemopreventive
7
20
Cardioprotective
9
18
Hepatoprotective
9
18
Anti-Tumor
9
17
Antihypertensive Agents
4
17
Chemoprotective Agents
6
17
Interleukin-6 Downregulation
9
17
NF-kappaB Inhibitor
10
17
Cell cycle arrest
10
16
Neurogenesis
8
14
Antipsychotic Agents
8
12
Chemosensitizer
8
12
Interleukin-1 beta downregulation
7
12
Matrix metalloproteinase-9 (MMP-9) inhibitor
2
12
Anxiolytic
2
11
Interferon Gamma Reducer
5
11
Anticarcinogenic Agents
7
10
Brain-derived neurotrophic factor modulator
5
10
GABA Modulators
1
10
MicroRNA modulator
6
10
Superoxide Dismutase Up-regulation
4
10
Enzyme Inhibitors
3
9
Nitric Oxide Inhibitor
3
8
Cannabinoid Receptor Antagonist/Inverse Agonist
3
7
Gastrointestinal Agents
5
7
Hypolipidemic
2
7
P38 Mitogen-Activated Protein Kinase Modulator
2
7
Anti-Angiogenic
6
6
Anti-Bacterial Agents
6
6
Vascular Cell Adhesion Molecule-1 Inhibitor
2
6
Appetite Stimulants
3
5
Cytotoxic
3
5
Immunomodulatory: Th17 downregulation
3
5
Neuritogenic
3
5
Radiosensitizer
2
5
Anti-Fibrotic
3
4
Anti-atherogenic
1
4
Antiviral Agents
4
4
Caspase-3 Activation
3
4
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor
1
4
Interleukin-10 downregulation
2
4
Interleukin-17 downregulation
3
4
Interleukin-4 downregulation
2
4
Interleukin-8 downregulation
3
4
Matrix metalloproteinase-2 (MMP-2) inhibitor
2
4
Osteoprotective
3
4
Prostaglandin PGE2 downregulation
2
4
Vascular Endothelial Growth Factor A Inhibitor
2
4
Vascular Endothelial Growth Factor Regulator
2
4
Gastroprotective
2
3
Matrix metalloproteinase-1 (MMP-1) inhibitor
2
3
Prophylactic Agents
2
3
Renoprotective
2
3
Sedative effects
1
3
Vanilloid Receptor-1 Modulator
1
3
Aldose reductase inhibitor
1
2
Anti-Androgen
1
2
Anticholesteremic Agents
1
2
Antimicrobial
1
2
Calcium Channel Blockers
1
2
Catalase Up-Regulation
1
2
Cyclooxygenase Inhibitors
1
2
Enzyme Activators
1
2
Epidermal growth factor receptor (EGFR) inhibitor
1
2
Glycine Agents
1
2
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
2
2
Immunomodulatory: T-Cell down-regulation
1
2
Immunostimulatory
1
2
Interleukin-10 upregulation
1
2
Interleukin-12 downregulation
1
2
Interleukin-2 Downregulation
1
2
Interleukin-5 downregulation
1
2
Intracellular adhesion molecule-1 (ICAM-1)
1
2
Malondialdehyde Down-regulation
1
2
Neuroplasticity enhancement
1
2
Pancreato Protective Agents
1
2
Photoprotective
2
2
Redox Modulator
1
2
Topoisomerase II Inhibitor
2
2
interleukin-13 down-regulation
1
2
Acetylcholinesterase Inhibitor
1
1
Anti-Allergic Agents
1
1
Anti-Cachexic Agents
1
1
Anti-Infective Agents
1
1
Anti-Proliferative
1
1
Anti-Psychotic
1
1
Antifungal Agents
1
1
Caspase-8 activation
1
1
Caspase-9 Activation
1
1
Cyclooxygenase 1 Inhibitor
1
1
Interleukin-2 upregulation
1
1
NADPH Oxidase Inhibitors
1
1
Neuroimmunomodulation
1
1
Nrf2 activation
1
1
Paraptosis
1
1
Regenerative
1
1
Transient receptor potential vanilloid type-2 activation
1
1
Tumor Suppressor Protein p53 Upregulation
1
1
Wnt/β-catenin signaling pathway modulation
1
1
apoptosis
1
1
Research Articles
776
Cumulative Knowledge Score
1255
Overall Research Rating
EXCELLENT
Related Topics
Delta-tetrahydrocannabinol (THC) is a Sub of the following Topics
Marijuana
Cannabis
View the Evidence:
920 Abstracts with Delta-tetrahydrocannabinol (THC) Research
Filter by Study Type
Animal Study
Commentary
Human In Vitro
Human Study
Human: Case Report
In Vitro Study
Meta Analysis
Review
Transgenic Animal Study
Sort Abstracts
Limited to Members Only
By default, all articles on GreenMedInfo.com are sorted based on the content type which best reflects the data which most users are searching for. For instance, people viewing substances are generally most interested in viewing diseases that these substances have shown to have positive influences. This section is for allowing more advanced sorting methods. Currently, these advanced sorting methods are available for members only. If you are already a member, you can sign in by
clicking here
. If you do not currently have a user account, and would like to create one/become a member,
click here
to begin the singup process.
Currently Available Sorting Options
Article Published Date
- Sort all displayed articles by their published date
Quick Summary Fieldsets
- Sort alphabetically, rather than by Cumulative Knowledge
Cumulative Knowledge
- Default sorting method. Allows you to sort descendingly
Free Sample of Member-Only Features
Although all 30,000+ articles on GreenMedInfo.com are made entirely free to view as an educational service to the public, we provide a powerful set of enhanced data comprehension and retrieval tools for subscribing members. Above you are viewing a free preview, limited to 10000 rows, of the membership feature called "
Cumulative Knowledge
" (
learn more
).
The
Focus Article Feature
is not enabled.
Upgrading to the
Friend
membership gives you access to unlimited rows of Cumulative Knowledge data.
To Participate
Click here
to login
Click here
to order a membership
[+]
Efficacy, safety, and regulation of cannabidiol on chronic pain.
Jun 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cureus. 2022 Jul ;14(7):e26913. Epub 2022 Jul 16. PMID:
35860716
Article Published Date
: Jun 30, 2022
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Cannabidiol
Diseases
:
Chronic Pain
Pharmacological Actions
:
Analgesics
[+]
A review and meta-analysis of the efficacy and safety of cannabidiol in epilepsy.
Nov 02, 2018
Click here to read the entire abstract
Pubmed Data
: Drugs. 2018 Nov 3. Epub 2018 Nov 3. PMID:
30390221
Article Published Date
: Nov 02, 2018
Study Type
: Meta Analysis
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
A systematic review and meta-analysis off the effects of cannabinoids in Amyotrophic lateral sclerosis murine models.
Dec 05, 2018
Click here to read the entire abstract
Pubmed Data
: J Neurochem. 2018 Dec 6. Epub 2018 Dec 6. PMID:
30520038
Article Published Date
: Dec 05, 2018
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Cannabinoids
Diseases
:
Amyotrophic lateral sclerosis (ALS)
[+]
Adjunctive CBD resulted in a greater reduction in convulsive seizure frequency.
Feb 09, 2020
Click here to read the entire abstract
Pubmed Data
: CNS Drugs. 2020 Feb 10. Epub 2020 Feb 10. PMID:
32040850
Article Published Date
: Feb 09, 2020
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Cannabidiol
Diseases
:
Dravet syndrome
Pharmacological Actions
:
Anticonvulsants
[+]
Cannabinoids may have possible therapeutic properties for the management of the multiple sclerosis.
Nov 19, 2010
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2010 Nov 19. Epub 2010 Nov 19. PMID:
21094240
Article Published Date
: Nov 19, 2010
Study Type
: Meta Analysis
Additional Links
Substances
:
Cannabinoids
Diseases
:
Multiple Sclerosis
[+]
Cannabinoids significantly reduced infarct volume and improve functional outcome in experimental stroke models.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: J Cereb Blood Flow Metab. 2015 Mar ;35(3):348-58. Epub 2014 Dec 10. PMID:
25492113
Article Published Date
: Feb 28, 2015
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Cannabinoids
Diseases
:
Stroke
,
Stroke: Attenuation/Recovery
Pharmacological Actions
:
Neuroprotective Agents
[+]
Selective cannabinoids provide a small analgesic benefit in patients with chronic neuropathic pain.
May 18, 2017
Click here to read the entire abstract
Pubmed Data
: Anesth Analg. 2017 May 19. Epub 2017 May 19. PMID:
28537982
Article Published Date
: May 18, 2017
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Cannabinoids
Diseases
:
Neuropathic Pain
Pharmacological Actions
:
Analgesics
[+]
The median effective dose of morphine administered in combination with THC is 3.6 times lower than of morphine alone.
Mar 21, 2017
Click here to read the entire abstract
Pubmed Data
: Neuropsychopharmacology. 2017 Mar 22. Epub 2017 Mar 22. PMID:
28327548
Article Published Date
: Mar 21, 2017
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Cannabinoids
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Morphine Tolerance/Dependence
,
Opioid Tolerance/Dependence
Additional Keywords
:
Medication Reduction
[+]
This meta-analysis and systematic review has highlighted the haemodynamic effects of CBD.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2017 ;8:81. Epub 2017 Feb 24. PMID:
28286481
Article Published Date
: Dec 31, 2016
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Cannabidiol
Diseases
:
Stroke
Pharmacological Actions
:
Vasodilator Agents
[+]
Cannabidiol Treatment for Neurological, cognitive, and psychiatric symptoms in Sturge-Weber Syndrome.
Jan 31, 2023
Click here to read the entire abstract
Pubmed Data
: Pediatr Neurol. 2023 Feb ;139:24-34. Epub 2022 Nov 12. PMID:
36508880
Article Published Date
: Jan 31, 2023
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Migraines
,
Psychiatric Disorders
Pharmacological Actions
:
Anti-Anxiety Agents
[+]
A case report of a female patient who demonstrated disease response after declining standard therapy and taking a combination of Laetrile and CBD oil.
Jul 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Gynecol Oncol Rep. 2019 Aug ;29:10-12. Epub 2019 May 17. PMID:
31193514
Article Published Date
: Jul 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Amygdalin (laetrile)
,
Cannabidiol
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
[+]
A low dose of THC produces subjective stress-relieving effects in line with those commonly reported among cannabis users.
May 29, 2017
Click here to read the entire abstract
Pubmed Data
: Drug Alcohol Depend. 2017 May 30 ;177:136-144. Epub 2017 May 30. PMID:
28599212
Article Published Date
: May 29, 2017
Study Type
: Human Study
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
Diseases
:
Anxiety
,
Stress
Pharmacological Actions
:
Anti-Anxiety Agents
[+]
A phase-2 pilot study of a therapeutic combination of Δ 9-tetrahydracannabinol and palmitoylethanolamide for adults with Tourette's syndrome.
Aug 02, 2021
Click here to read the entire abstract
Pubmed Data
: J Neuropsychiatry Clin Neurosci. 2021 Aug 3:appineuropsych19080178. Epub 2021 Aug 3. PMID:
34340527
Article Published Date
: Aug 02, 2021
Study Type
: Human Study
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
,
Palmitoylethanolamide
Diseases
:
Tourette Syndrome
[+]
A positive THC screen is associated with decreased mortality in adult patients sustaining traumatic brain injury.
Sep 30, 2014
Click here to read the entire abstract
Pubmed Data
: Am Surg. 2014 Oct ;80(10):979-83. PMID:
25264643
Article Published Date
: Sep 30, 2014
Study Type
: Human Study
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
Diseases
:
Brain Injury: Traumatic
Additional Keywords
:
Mortality
,
Significant Treatment Outcome
[+]
A single dose of cannabidiol reduces blood pressure in healthy volunteers.
Jun 14, 2017
Click here to read the entire abstract
Pubmed Data
: JCI Insight. 2017 Jun 15 ;2(12). Epub 2017 Jun 15. PMID:
28614793
Article Published Date
: Jun 14, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
[+]
A single-dose treatment with Delta(9)-THC is effective and safe in treating tics and obsessive-compulsive disorder in Tourette Syndrome.
Sep 24, 2008
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2008 Sep 24;56(18):8601-8. Epub 2008 Aug 30. PMID:
11951146
Article Published Date
: Sep 24, 2008
Study Type
: Human Study
Additional Links
Substances
:
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Obsessive-Compulsive Disorder
,
Tourette Syndrome
[+]
A tetrahydrocannabinol:cannabidiol (THC:CBD) extract is efficacious for relief of pain in patients with advanced cancer pain not fully relieved by strong opioids.
Jul 01, 2009
Click here to read the entire abstract
Pubmed Data
: Hum Reprod. 2009 Jul;24(7):1717-25. Epub 2009 Mar 11. PMID:
19896326
Article Published Date
: Jul 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Cancers: All
,
Pain
Pharmacological Actions
:
Analgesics
[+]
Acute cannabidiol administration at a dose of 300 mg decreased anxiety in patients with Parkinson's disease.
Jan 06, 2020
Click here to read the entire abstract
Pubmed Data
: J Psychopharmacol. 2020 Jan 7:269881119895536. Epub 2020 Jan 7. PMID:
31909680
Article Published Date
: Jan 06, 2020
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Anxiety
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Anxiety Agents
[+]
Add-on cannabidiol may be an efficacious long-term treatment option for treatment-resistant epilepsies.
Jul 11, 2018
Click here to read the entire abstract
Pubmed Data
: Epilepsia. 2018 Jul 12. Epub 2018 Jul 12. PMID:
29998598
Article Published Date
: Jul 11, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
Artisanal cannabidiol-enriched cannabis may be an effective and safe long-term treatment for refractory epilepsy.
Jun 27, 2022
Click here to read the entire abstract
Pubmed Data
: Pediatr Neurol. 2022 Jun 28 ;136:15-19. Epub 2022 Jun 28. PMID:
36049378
Article Published Date
: Jun 27, 2022
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
Cannabidiol acts at 5-HT 1A receptors in the human brain: Relevance for treating temporal lobe epilepsy.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Behav Neurosci. 2020 ;14:611278. Epub 2020 Dec 15. PMID:
33384591
Article Published Date
: Dec 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Temporal Lobe Epilepsy (TLE)
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cannabidiol as a treatment for arthritis and joint pain.
Aug 23, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cannabis Res. 2022 Aug 24 ;4(1):47. Epub 2022 Aug 24. PMID:
35999581
Article Published Date
: Aug 23, 2022
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Arthritis
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
Additional Keywords
:
Medication Reduction
[+]
Cannabidiol as an adjuvant treatment in adults with drug-resistant focal epilepsy.
Jun 30, 2023
Click here to read the entire abstract
Pubmed Data
: Epilepsy Behav. 2023 Jul ;144:109210. Epub 2023 May 15. PMID:
37196452
Article Published Date
: Jun 30, 2023
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
Cannabidiol attenuates insular dysfunction during motivational salience processing in subjects at clinical high risk for psychosis.
Aug 21, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Transl Psychiatry. 2019 Aug 22 ;9(1):203. Epub 2019 Aug 22. PMID:
31439831
Article Published Date
: Aug 21, 2019
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Psychoses
Additional Keywords
:
Risk Reduction
[+]
Cannabidiol could be useful in Dravet syndrome treatments.
Mar 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmacol Res Perspect. 2016 Apr ;4(2):e00220. Epub 2016 Mar 5. PMID:
27069631
Article Published Date
: Mar 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Dravet syndrome
,
Endocannabinoid Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Endocannabinoid System
[+]
Cannabidiol could reduce severe behavioural problems in children and adolescents with intellectual disability.
May 31, 2020
Click here to read the entire abstract
Pubmed Data
: Br J Clin Pharmacol. 2020 Jun 1. Epub 2020 Jun 1. PMID:
32478863
Article Published Date
: May 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Child Behavior Disorders
,
Learning disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cannabidiol enhances verbal episodic memory in healthy young participants.
Sep 06, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Psychiatr Res. 2021 Sep 7 ;143:327-333. Epub 2021 Sep 7. PMID:
34536664
Article Published Date
: Sep 06, 2021
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cannabidiol for rapid eye movement sleep behavior disorder.
Mar 21, 2021
Click here to read the entire abstract
Pubmed Data
: Mov Disord. 2021 Mar 22. Epub 2021 Mar 22. PMID:
33754375
Article Published Date
: Mar 21, 2021
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Parkinson's Disease
[+]
Cannabidiol for the treatment of crack-cocaine craving.
Oct 29, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Braz J Psychiatry. 2020 Oct 30. Epub 2020 Oct 30. PMID:
33146345
Article Published Date
: Oct 29, 2020
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Cocaine Addiction
[+]
Cannabidiol for treating drug-resistant epilepsy in children.
Aug 12, 2018
Click here to read the entire abstract
Pubmed Data
: Med J Aust. 2018 Aug 13. Epub 2018 Aug 13. PMID:
30092753
Article Published Date
: Aug 12, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
[+]
Cannabidiol for treating Lennox-Gastaut Syndrome and Dravet Syndrome in Korea
Dec 27, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Korean Med Sci. 2020 Dec 28 ;35(50):e427. Epub 2020 Dec 28. PMID:
33372424
Article Published Date
: Dec 27, 2020
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Dravet syndrome
,
Lennox-Gastaut Syndrome
Pharmacological Actions
:
Anticonvulsants
[+]
Cannabidiol has antipsychotic properties which balance out the psychotomimetic effects of THC in cannabis.
Apr 01, 2008
Click here to read the entire abstract
Pubmed Data
: Br J Psychiatry. 2008 Apr;192(4):306-7. PMID:
18378995
Article Published Date
: Apr 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Delirium: Drug-Induced
,
Marijuana Addiction/Withdrawal
Additional Keywords
:
The Whole is Superior to the Monochemical Part
,
Whole Food Balance
[+]
Cannabidiol improves frequency and severity of seizures and reduces adverse events.
Aug 08, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Epilepsy Behav. 2018 Aug 9. Epub 2018 Aug 9. PMID:
30100226
Article Published Date
: Aug 08, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Seizures
Pharmacological Actions
:
Anticonvulsants
[+]
Cannabidiol in children with treatment-resistant epilepsy with myoclonic-atonic seizures.
May 31, 2023
Click here to read the entire abstract
Pubmed Data
: Epilepsy Behav. 2023 Jun ;143:109245. Epub 2023 May 12. PMID:
37182500
Article Published Date
: May 31, 2023
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
,
Seizures
,
Sturge-Weber Syndrome
Pharmacological Actions
:
Anticonvulsants
[+]
Cannabidiol in the treatment of post-traumatic stress disorder.
Dec 12, 2018
Click here to read the entire abstract
Pubmed Data
: J Altern Complement Med. 2018 Dec 13. Epub 2018 Dec 13. PMID:
30543451
Article Published Date
: Dec 12, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Post-Traumatic Stress Disorders (PTSD)
Additional Keywords
:
Significant Treatment Outcome
[+]
Cannabidiol levels in different strains of cannabis may determine the degree to which THC interferes with memory in users.
Oct 01, 2010
Click here to read the entire abstract
Pubmed Data
: Br J Psychiatry. 2010 Oct;197(4):285-90. PMID:
20884951
Article Published Date
: Oct 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Marijuana Addiction/Withdrawal
,
Memory Disorders
[+]
Cannabidiol may be an effective and well-tolerated treatment option for patients with refractory seizures in Tuberous sclerosis complex.
Sep 30, 2016
Click here to read the entire abstract
Pubmed Data
: Epilepsia. 2016 Oct ;57(10):1617-1624. Epub 2016 Aug 3. PMID:
27696387
Article Published Date
: Sep 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Tuberous Sclerosis
Pharmacological Actions
:
Anticonvulsants
[+]
Cannabidiol may hold benefit for anxiety-related disorders.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Perm J. 2019 ;23. PMID:
30624194
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Anxiety
Pharmacological Actions
:
Anti-Anxiety Agents
[+]
Cannabidiol might reduce seizure frequency and might have an adequate safety profile in children and young adults with treatment-resistant epilepsy.
Dec 22, 2015
Click here to read the entire abstract
Pubmed Data
: Lancet Neurol. 2015 Dec 23. Epub 2015 Dec 23. PMID:
26724101
Article Published Date
: Dec 22, 2015
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
,
Epilepsy: Childhood
Pharmacological Actions
:
Anticonvulsants
[+]
Cannabidiol reduces anxiety in social anxiety disorder through modulating the limbic and paralimbic brain areas.
Sep 09, 2010
Click here to read the entire abstract
Pubmed Data
: J Psychopharmacol. 2010 Sep 9. Epub 2010 Sep 9. PMID:
20829306
Article Published Date
: Sep 09, 2010
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Anxiety Disorders
,
Social Anxiety Disorder (SAD)
Pharmacological Actions
:
Anxiolytic
[+]
Cannabidiol resulted in a greater reduction in convulsive-seizure frequency among patients with Dravet syndrome.
Jan 24, 2017
Click here to read the entire abstract
Pubmed Data
: N Engl J Med. 2017 05 25 ;376(21):2011-2020. PMID:
28538134
Article Published Date
: Jan 24, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Dravet syndrome
Pharmacological Actions
:
Anticonvulsants
Additional Keywords
:
Significant Treatment Outcome
[+]
Cannabidiol treatment in children with treatment resistant epilepsies led to 42% of children reporting a greater than 80% reduction in seizure frequency and 32% reporting a 25-60% seizure reduction.
Nov 30, 2013
Click here to read the entire abstract
Pubmed Data
: Epilepsy Behav. 2013 Dec ;29(3):574-7. PMID:
24237632
Article Published Date
: Nov 30, 2013
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
,
Epilepsy: Childhood
,
Epileptic Seizures
Pharmacological Actions
:
Anticonvulsants
Additional Keywords
:
Treatment Resistant
[+]
Cannabidiol treatment yielded a significant positive effect on seizure load in patients with intractable epilepsy.
Jan 05, 2016
Click here to read the entire abstract
Pubmed Data
: Seizure. 2016 Jan 6 ;35:41-44. Epub 2016 Jan 6. PMID:
26800377
Article Published Date
: Jan 05, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Epilepsy
,
Epilepsy: Childhood
Pharmacological Actions
:
Anticonvulsants
Additional Keywords
:
Plant Extracts
,
Significant Treatment Outcome
[+]
Cannabinoid treatment for autism: a proof-of-concept randomized trial.
Feb 02, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Autism. 2021 Feb 3 ;12(1):6. Epub 2021 Feb 3. PMID:
33536055
Article Published Date
: Feb 02, 2021
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Autism Spectrum Disorders
[+]
Cannabinoids may have therapeutic value in the treatment of tics in Tourette syndrome.
Oct 01, 2003
Click here to read the entire abstract
Pubmed Data
: Expert Opin Pharmacother. 2003 Oct;4(10):1717-25. PMID:
14521482
Article Published Date
: Oct 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Tourette Syndrome
[+]
Cannabis and cannabinoids in cancer pain management.
May 31, 2020
Click here to read the entire abstract
Pubmed Data
: Curr Opin Support Palliat Care. 2020 Jun ;14(2):87-93. PMID:
32332209
Article Published Date
: May 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Cancer: Pain
Pharmacological Actions
:
Analgesics
[+]
Cannabis cigarettes may be effective at ameliorating neuropathic pain.
Jun 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Pain. 2008 Jun;9(6):506-21. Epub 2008 Apr 10. PMID:
18403272
Article Published Date
: Jun 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Marijuana
Diseases
:
Neuropathic Pain
[+]
Cannabis containing equivalent concentrations of delta-9-tetrahydrocannabinol and cannabidiol induces less state anxiety than THC-dominant cannabis.
Oct 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Psychopharmacology (Berl). 2022 Nov ;239(11):3731-3741. Epub 2022 Oct 13. PMID:
36227352
Article Published Date
: Oct 31, 2022
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Anxiety
Pharmacological Actions
:
Anti-Anxiety Agents
[+]
Cannabis could be potentially beneficial reduction in systemic inflammation and immune activation in the context of antiretroviral-treated HIV infection.
Feb 16, 2018
Click here to read the entire abstract
Pubmed Data
: Clin Infect Dis. 2018 Feb 17. Epub 2018 Feb 17. PMID:
29471387
Article Published Date
: Feb 16, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
HIV Infections
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Immunomodulatory
[+]
Cannabis extracts can be a useful and safe option for patients with MS with moderate to severe spasticity resistant to common antispastic drugs.
May 08, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neurol Neurosurg Psychiatry. 2016 May 9. Epub 2016 May 9. PMID:
27160523
Article Published Date
: May 08, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Multiple Sclerosis
Additional Keywords
:
Plant Extracts
[+]
Cannabis extracts can be considered an alternative in patients with spasticity associated with chronic spinal cord injury.
Sep 30, 2017
Click here to read the entire abstract
Pubmed Data
: Rev Neurol. 2017 Oct 1 ;65(7):295-302. PMID:
28929471
Article Published Date
: Sep 30, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Spinal Cord Injuries
Additional Keywords
:
Plant Extracts
[+]
Cannabis in ASD patients appears to be well tolerated, safe and effective option to relieve symptoms associated with ASD.
Jan 16, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2019 Jan 17 ;9(1):200. Epub 2019 Jan 17. PMID:
30655581
Article Published Date
: Jan 16, 2019
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Autism Spectrum Disorders
[+]
Cannabis is well tolerated and effective in the treatment of HIV-associated neuropathy
Feb 13, 2007
Click here to read the entire abstract
Pubmed Data
: Neurology. 2007 Feb 13;68(7):515-21. PMID:
17296917
Article Published Date
: Feb 13, 2007
Study Type
: Human Study
Additional Links
Substances
:
Marijuana
Diseases
:
Neuropathy: HIV associated
[+]
Cannabis is well-tolerated and efficacious in the treatment of neuropathic pain from brachial plexus avulsion.
Dec 01, 2004
Click here to read the entire abstract
Pubmed Data
: Pain. 2004 Dec;112(3):299-306. PMID:
15561385
Article Published Date
: Dec 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Brachial Plexus Neuropathies
,
Neuropathic Pain
Additional Keywords
:
Plant Extracts
[+]
Cannabis may have therapeutic value in the treatment of Tourette syndrome.
Dec 01, 1998
Click here to read the entire abstract
Pubmed Data
: Acta Psychiatr Scand. 1998 Dec;98(6):502-6. PMID:
9879795
Article Published Date
: Dec 01, 1998
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Obsessive-Compulsive Disorder
,
Tourette Syndrome
[+]
Cannabis may improve pain, mood and sleep in some patients with chronic pain.
Jun 01, 2002
Click here to read the entire abstract
Pubmed Data
: Pain Res Manag. 2002 Summer;7(2):95-9. PMID:
12185373
Article Published Date
: Jun 01, 2002
Study Type
: Human Study
Additional Links
Substances
:
Marijuana
Diseases
:
Insomnia
,
Pain
[+]
Cannabis, used with adequate precaution, appears to be moderately efficacious for the treatment of chronic pain.
Sep 01, 2009
Click here to read the entire abstract
Pubmed Data
: Pain Med. 2009 Sep 1. PMID:
19732371
Article Published Date
: Sep 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Marijuana
Diseases
:
Pain
Pharmacological Actions
:
Analgesics
[+]
Cannabis-based medicine is effective in reducing pain and sleep disturbance in patients with multiple sclerosis related central neuropathic pain and is mostly well tolerated.
Sep 27, 2005
Click here to read the entire abstract
Pubmed Data
: Neurology. 2005 Sep 27;65(6):812-9. PMID:
16186518
Article Published Date
: Sep 27, 2005
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Insomnia
,
Multiple Sclerosis
,
Pain
,
Sleep Disorders
Pharmacological Actions
:
Analgesics
[+]
Cannabis-based medicine may represent a useful new agent for treatment of the symptomatic relief of spasticity in MS.
Feb 28, 2007
Click here to read the entire abstract
Pubmed Data
: Eur J Neurol. 2007 Mar ;14(3):290-6. PMID:
17355549
Article Published Date
: Feb 28, 2007
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabinoids
,
Cannabis
Diseases
:
Multiple Sclerosis
Additional Keywords
:
Plant Extracts
[+]
CBD can reduce anxiety severity and has an adequate safety profile in young people with treatment-resistant anxiety disorders.
Jan 02, 2022
Click here to read the entire abstract
Pubmed Data
: J Clin Psychiatry. 2022 08 3 ;83(5). Epub 2022 Aug 3. PMID:
35921510
Article Published Date
: Jan 02, 2022
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Anxiety
Pharmacological Actions
:
Antidepressive Agents
[+]
CBD could be beneficial for the treatment of brain tumor-related epilepsy.
Oct 23, 2017
Click here to read the entire abstract
Pubmed Data
: Neurocase. 2017 Oct 24:1-5. Epub 2017 Oct 24. PMID:
29063814
Article Published Date
: Oct 23, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Brain Cancer
,
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
CBD enriched hemp oil could be beneficial in girls with adverse drug effects following human papillomavirus (HPV) vaccine.
Jan 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Isr Med Assoc J. 2017 Feb ;19(2):79-84. PMID:
28457055
Article Published Date
: Jan 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Hemp Seed
Diseases
:
Vaccine-induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antinoceceptive
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
Anti Therapeutic Actions
:
Vaccination: HPV (Gardasil)
[+]
CBD has anxiolytic properties in human volunteers submitted to a stressful situation.
Dec 31, 1992
Click here to read the entire abstract
Pubmed Data
: J Psychopharmacol. 1993 Jan ;7(1 Suppl):82-8. PMID:
22290374
Article Published Date
: Dec 31, 1992
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Anxiety
Pharmacological Actions
:
Anti-Anxiety Agents
[+]
CBD is a well supported co-medication and seems to prolong the survival of patients with glioblastoma multiforme.
Apr 30, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Diagn Progn. 2021 May-Jun;1(2):77-82. Epub 2021 May 3. PMID:
35403130
Article Published Date
: Apr 30, 2021
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Glioblastoma Multiforme
Pharmacological Actions
:
Chemotherapeutic
[+]
CBD may be effective, safe and well tolerated for the treatment of the psychosis in Parkinson's disease.
Oct 31, 2009
Click here to read the entire abstract
Pubmed Data
: J Psychopharmacol. 2009 Nov ;23(8):979-83. Epub 2008 Sep 18. PMID:
18801821
Article Published Date
: Oct 31, 2009
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Parkinson's Disease
,
Psychoses
[+]
CBD provides symptom relief in patients with gastroparesis and improves the tolerance of liquid nutrient intake.
Jul 21, 2023
Click here to read the entire abstract
Pubmed Data
: Clin Gastroenterol Hepatol. 2023 Jul 22. Epub 2023 Jul 22. PMID:
37482172
Article Published Date
: Jul 21, 2023
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Gastroparesis
Pharmacological Actions
:
Gastrointestinal Agents
[+]
CBD restores excitability and morphological impairment in epileptic models to pre-epilepsy control levels.
Mar 24, 2018
Click here to read the entire abstract
Pubmed Data
: Br J Pharmacol. 2018 Mar 25. Epub 2018 Mar 25. PMID:
29574880
Article Published Date
: Mar 24, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Neuroprotective Agents
[+]
CBD was found to have potential benefits as add-on therapy for refractory childhood epilepsies.
Mar 07, 2018
Click here to read the entire abstract
Pubmed Data
: Epilepsy Behav. 2018 Mar 8. Epub 2018 Mar 8. PMID:
29526578
Article Published Date
: Mar 07, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
CBD-rich botanical extract may be beneficial for symptomatic treatment of ulcerative colitis.
Mar 09, 2018
Click here to read the entire abstract
Pubmed Data
: Inflamm Bowel Dis. 2018 Mar 10. Epub 2018 Mar 10. PMID:
29538683
Article Published Date
: Mar 09, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Childbearing women have used marihuana medicinally to treat severe naseau and vomitng during pregnancy.
Nov 01, 2009
Click here to read the entire abstract
Pubmed Data
: Complement Ther Clin Pract. 2009 Nov;15(4):242-6. Epub 2009 Aug 15. PMID:
16401527
Article Published Date
: Nov 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Marijuana
Diseases
:
Nausea: Pregnancy-Associated
[+]
Chronic pain treatment with cannabidiol in kidney transplant patients in Uruguay.
Feb 28, 2018
Click here to read the entire abstract
Pubmed Data
: Transplant Proc. 2018 Mar ;50(2):461-464. PMID:
29579828
Article Published Date
: Feb 28, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Chronic Pain
,
Organ Transplantation: Kidney
Pharmacological Actions
:
Analgesics
[+]
Cognitive and behavioral effects of cannabidiol in patients with treatment-resistant epilepsy.
Nov 23, 2020
Click here to read the entire abstract
Pubmed Data
: Epilepsy Behav. 2020 Nov 24:107558. Epub 2020 Nov 24. PMID:
33246899
Article Published Date
: Nov 23, 2020
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Neuroprotective Agents
[+]
Delta-9-tetrahydrocannabinol appears to be therapeutic for nighttime agitation in severe dementia.
Apr 30, 2006
Click here to read the entire abstract
Pubmed Data
: Psychopharmacology (Berl). 2006 May ;185(4):524-8. Epub 2006 Mar 7. PMID:
16521031
Article Published Date
: Apr 30, 2006
Study Type
: Human Study
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
Diseases
:
Dementia
,
Sleep Disorders
[+]
Delta-tetrahydrocannabinol (THC) and cannabidiol have therapeutic value in the management of spasticity associated wtih multiple sclerosis.
Aug 01, 1996
Click here to read the entire abstract
Pubmed Data
: J Nutr Sci Vitaminol (Tokyo). 1996 Aug;42(4):325-37. PMID:
21456949
Article Published Date
: Aug 01, 1996
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Multiple Sclerosis
,
Muscle Spasticity
Pharmacological Actions
:
Antispasmodic
[+]
Delta9-tetrahydrocannabinol administration led to the inhibition of the VEGF Pathway in Two Patients with Glioblastoma Multiforme.
Aug 14, 2004
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Res. 2004 Aug 15 ;64(16):5617-23. PMID:
15313899
Article Published Date
: Aug 14, 2004
Study Type
: Animal Study, Human Study
Additional Links
Substances
:
Cannabinoids
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Glioblastoma Multiforme
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Gene Expression Regulation
[+]
Drivers under the influence of synthetic cannabinoids were more frequently impaired with confusion, disorientation, and incoherent, slurred speech than drivers under the influence of marijuana in this population evaluated by drug recognition experts.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Clin Toxicol (Phila). 2016 ;54(1):14-9. PMID:
26653952
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Impairment: Driving Related
Additional Keywords
:
Natural Versus Synthetics
,
Plant Extracts
Problem Substances
:
Synthetic Cannabinoids
[+]
Dronabinol is a safe long-term treatment option for neuropathic pain patients.
Oct 25, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur Neurol. 2017 Oct 26 ;78(5-6):320-329. Epub 2017 Oct 26. PMID:
29073592
Article Published Date
: Oct 25, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Multiple Sclerosis
,
Neuropathic Pain
Pharmacological Actions
:
Analgesics
[+]
Effect of cannabidiol on interictal epileptiform activity and sleep architecture in children with intractable epilepsy.
Jan 10, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: CNS Drugs. 2021 11 ;35(11):1207-1215. Epub 2021 Oct 22. PMID:
34687005
Article Published Date
: Jan 10, 2021
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
Effectiveness of cannabidiol in a prospective cohort of children with drug-resistant epileptic encephalopathy.
Jun 05, 2020
Click here to read the entire abstract
Pubmed Data
: Seizure. 2020 Jun 6 ;80:75-80. Epub 2020 Jun 6. PMID:
32544657
Article Published Date
: Jun 05, 2020
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Encephalopathy
Pharmacological Actions
:
Anticonvulsants
[+]
Effects of cannabidiol on brain excitation and inhibition systems.
Feb 05, 2019
Click here to read the entire abstract
Pubmed Data
: Neuropsychopharmacology. 2019 Feb 6. Epub 2019 Feb 6. PMID:
30758329
Article Published Date
: Feb 05, 2019
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Autism Spectrum Disorders
Pharmacological Actions
:
GABA Modulators
[+]
Effects of cannabidiol supplementation on skeletal muscle regeneration after intensive resistance training.
Aug 29, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2021 Aug 30 ;13(9). Epub 2021 Aug 30. PMID:
34578906
Article Published Date
: Aug 29, 2021
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Muscle Damage: Exercise-Induced
Therapeutic Actions
:
Exercise: Resistance Training
[+]
Efficacy and tolerance of cannabidiol in the treatment of epilepsy in patients with Rett syndrome.
Jul 23, 2023
Click here to read the entire abstract
Pubmed Data
: Epilepsia Open. 2023 Jul 24. Epub 2023 Jul 24. PMID:
37485779
Article Published Date
: Jul 23, 2023
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
,
Rett Syndrome
Pharmacological Actions
:
Anticonvulsants
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Efficacy of cannabidiol in convulsive and nonconvulsive seizure types associated with treatment-resistant epilepsies.
May 25, 2023
Click here to read the entire abstract
Pubmed Data
: Epilepsia. 2023 May 26. Epub 2023 May 26. PMID:
37243404
Article Published Date
: May 25, 2023
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
Eighty five percent of all parents reported a reduction in seizure frequency and 14% reported complete seizure freedom.
Apr 28, 2015
Click here to read the entire abstract
Pubmed Data
: Epilepsy Behav. 2015 Apr 29. Epub 2015 Apr 29. PMID:
25935511
Article Published Date
: Apr 28, 2015
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Epilepsy
,
Epilepsy: Childhood
Pharmacological Actions
:
Anticonvulsants
Additional Keywords
:
Plant Extracts
[+]
Evaluating cannabidiol expectancy effects on acute stress and anxiety in healthy adults.
Apr 03, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Psychopharmacology (Berl). 2021 Apr 4. Epub 2021 Apr 4. PMID:
33813611
Article Published Date
: Apr 03, 2021
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Anxiety
Pharmacological Actions
:
Anti-Anxiety Agents
[+]
Fibromyalgia patients saw many benefits from using CBD across multiple symptoms domains.
Jan 01, 2021
Click here to read the entire abstract
Pubmed Data
: J Pain. 2021 Jan 2. Epub 2021 Jan 2. PMID:
33400996
Article Published Date
: Jan 01, 2021
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Fibromyalgia
[+]
Highly purified cannabidiol in the treatment of drug-resistant epilepsies.
Sep 30, 2023
Click here to read the entire abstract
Pubmed Data
: Epilepsy Behav. 2023 Oct ;147:109409. Epub 2023 Sep 6. PMID:
37677907
Article Published Date
: Sep 30, 2023
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
In patients suffering from Tourette syndrome, treatment with Delta(9)-THC causes neither acute nor long-term cognitive deficits.
Feb 01, 2003
Click here to read the entire abstract
Pubmed Data
: Neuropsychopharmacology. 2003 Feb;28(2):384-8. PMID:
12589392
Article Published Date
: Feb 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Tourette Syndrome
[+]
In this trial cannabis induced a clinical remission in 50% of patients with long standing Crohn's disease with 80% nonresponse or intolerance to anti–TNF-α treatment.
Sep 30, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Gastroenterol Hepatol. 2013 Oct ;11(10):1276-1280.e1. Epub 2013 May 4. PMID:
23648372
Article Published Date
: Sep 30, 2013
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Natural Substances Versus Drugs
,
Significant Treatment Outcome
[+]
Inhaled cannabis demonstrated a dose dependent reduction in diabetic peripheral neuropathy pain in patients with treatment refractory pain.
Jun 30, 2015
Click here to read the entire abstract
Pubmed Data
: J Pain. 2015 Jul ;16(7):616-27. Epub 2015 Apr 3. PMID:
25843054
Article Published Date
: Jun 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Diabetic Neuropathies
Pharmacological Actions
:
Analgesics
Additional Keywords
:
Dose Response
,
Significant Treatment Outcome
[+]
Long-term add-on CBD treatment had an acceptable safety profile in patients with Lennox-Gastaut syndrome and led to sustained reductions in seizures.
Feb 10, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Epilepsia. 2019 Feb 11. Epub 2019 Feb 11. PMID:
30740695
Article Published Date
: Feb 10, 2019
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Lennox-Gastaut Syndrome
Pharmacological Actions
:
Anticonvulsants
[+]
Long-term cannabidiol treatment in patients with Dravet syndrome.
Dec 22, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Epilepsia. 2018 Dec 23. Epub 2018 Dec 23. PMID:
30582156
Article Published Date
: Dec 22, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Dravet syndrome
[+]
Long-term efficacy and safety of cannabidiol in patients with treatment-resistant epilepsies.
Feb 28, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Epilepsia. 2023 Mar ;64(3):619-629. Epub 2023 Jan 10. PMID:
36537757
Article Published Date
: Feb 28, 2023
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
,
Seizures
Pharmacological Actions
:
Anticonvulsants
[+]
Marihuana may have therapeutic value in overcoming crack addiction.
Oct 01, 1999
Click here to read the entire abstract
Pubmed Data
: J Psychoactive Drugs. 1999 Oct-Dec;31(4):451-5. PMID:
10681113
Article Published Date
: Oct 01, 1999
Study Type
: Human Study
Additional Links
Substances
:
Marijuana
Diseases
:
Crack Addiction/Withdrawal
[+]
Observations from this study suggest that cannabis use is associated with lower prevalence of NAFLD.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(4):e0176416. Epub 2017 Apr 25. PMID:
28441459
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Additional Keywords
:
Risk Reduction
,
Significant Treatment Outcome
[+]
Orally administered cannabis extract may provide a therapeutic option to other drugs in the treatment of spasticity in patients with multiple sclerosis
Aug 01, 2004
Click here to read the entire abstract
Pubmed Data
: Mult Scler. 2004 Aug;10(4):417-24. PMID:
15327040
Article Published Date
: Aug 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Multiple Sclerosis
,
Muscle Spasticity
[+]
Palmitoylethanolamide and cannabidiol prevent inflammation-induced hyperpermeability of the human gut.
Jan 03, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Inflamm Bowel Dis. 2019 05 4 ;25(6):1006-1018. PMID:
31054246
Article Published Date
: Jan 03, 2019
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Palmitoylethanolamide
Diseases
:
Inflammation
,
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastroprotective
[+]
Parents' reports suggest that cannabidiol may improve autism spectrum disorder comorbidity symptoms.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2018 ;9:1521. Epub 2019 Jan 9. PMID:
30687090
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
Diseases
:
Autism Spectrum Disorders
[+]
Phytocannabinoids can be a low-cost and well-tolerated therapy to reduce symptoms and increase the quality of life of patients with fibromyalgia.
Sep 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pain Med. 2020 Oct 1 ;21(10):2212-2218. PMID:
33118602
Article Published Date
: Sep 30, 2020
Study Type
: Human Study
Additional Links
Substances
:
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Fibromyalgia
Pharmacological Actions
:
Antidepressive Agents
[+]
Prolonged CBD treatment appears to have promising therapeutic effects for improving psychological symptoms and cognition in regular cannabis users.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cannabis Cannabinoid Res. 2018 ;3(1):21-34. Epub 2018 Mar 1. PMID:
29607408
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Pharmacological Actions
:
Neuroprotective Agents
[+]
Purified pharmaceutical CBD may be an effective and safe adjunctive therapy in refractory epileptic spasms.
Mar 09, 2020
Click here to read the entire abstract
Pubmed Data
: Epilepsy Behav. 2020 Mar 10 ;106:106988. Epub 2020 Mar 10. PMID:
32169600
Article Published Date
: Mar 09, 2020
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
Safety and tolerability of cannabidiol in Parkinson disease.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cannabis Cannabinoid Res. 2020 ;5(4):326-336. Epub 2020 Dec 15. PMID:
33381646
Article Published Date
: Dec 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Sativex is safe and well tolerated in patients with HD, with no severe adverse events or clinical worsening.
May 08, 2016
Click here to read the entire abstract
Pubmed Data
: J Neurol. 2016 May 9. Epub 2016 May 9. PMID:
27159993
Article Published Date
: May 08, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Huntington Disease
Additional Keywords
:
Plant Extracts
,
Safety of Natural Substances
[+]
Smoked medicinal cannabis is well tolerated and effective in treating neuropathic pain in patients with HIV.
Feb 01, 2009
Click here to read the entire abstract
Pubmed Data
: Neuropsychopharmacology. 2009 Feb;34(3):672-80. Epub 2008 Aug 6. PMID:
18688212
Article Published Date
: Feb 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Marijuana
Diseases
:
Neuropathic Pain: HIV-associated
[+]
Tetrahydrocannabivarin could represent a new therapeutic agent in glycemic control in subjects with type 2 diabetes.
Aug 28, 2016
Click here to read the entire abstract
Pubmed Data
: Diabetes Care. 2016 Aug 29. Epub 2016 Aug 29. PMID:
27573936
Article Published Date
: Aug 28, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabinoids
Diseases
:
Diabetes Mellitus: Type 2
,
Hypoglycemia
Pharmacological Actions
:
Hypoglycemic Agents
[+]
THC and CBD was effective in select patients with central neuropathic pain and multiple sclerosis.
Aug 31, 2007
Click here to read the entire abstract
Pubmed Data
: Clin Ther. 2007 Sep ;29(9):2068-79. PMID:
18035205
Article Published Date
: Aug 31, 2007
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Multiple Sclerosis
,
Neuropathic Pain
Pharmacological Actions
:
Analgesics
Additional Keywords
:
Plant Extracts
[+]
THC appears therapeutic for anorexia and disturbed behavior in patients with Alzheimer's disease.
Aug 31, 1997
Click here to read the entire abstract
Pubmed Data
: Int J Geriatr Psychiatry. 1997 Sep ;12(9):913-9. PMID:
9309469
Article Published Date
: Aug 31, 1997
Study Type
: Human Study
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
Diseases
:
Anorexia: Dementia-Associated
Pharmacological Actions
:
Antidepressive Agents
[+]
THC is effective and safe in the treatment of tics.
Apr 01, 2003
Click here to read the entire abstract
Pubmed Data
: J Clin Psychiatry. 2003 Apr;64(4):459-65. PMID:
12716250
Article Published Date
: Apr 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Tourette Syndrome
[+]
THC/CBD oromucosal spray has shown to be effective in improving overactive bladder symptoms in multiple sclerosis patients.
Oct 18, 2017
Click here to read the entire abstract
Pubmed Data
: Neurol Sci. 2017 Oct 19. Epub 2017 Oct 19. PMID:
29052091
Article Published Date
: Oct 18, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Multiple Sclerosis
,
Overactive Bladder
[+]
THC/CBD spray was beneficial for the majority of patients with PNP associated with diabetes or allodynia.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: J Neurol. 2015 Jan ;262(1):27-40. Epub 2014 Sep 30. PMID:
25270679
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Neuropathic Pain
,
Peripheral Nerve Diseases
Pharmacological Actions
:
Analgesics
[+]
THC:CBD oromucosal spray provided symptomatic relief of MS spasticity with good tolerability in a relevant number of previously resistant patients.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Eur Neurol. 2015 ;74(3-4):178-85. Epub 2015 Nov 17. PMID:
26571097
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Multiple Sclerosis
Additional Keywords
:
Plant Extracts
[+]
THC:CBD oromucosal spray provided symptomatic relief of MSS and related troublesome symptoms.
Oct 12, 2016
Click here to read the entire abstract
Pubmed Data
: Eur Neurol. 2016 Oct 13 ;76(5-6):216-226. Epub 2016 Aug 13. PMID:
27732980
Article Published Date
: Oct 12, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Multiple Sclerosis
[+]
The anti-inflammatory activity of Cannabis extracts on colon epithelial cells derives from a fraction of the extract that contains THCA.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cannabis Cannabinoid Res. 2017 ;2(1):167-182. Epub 2017 Jul 1. PMID:
29082314
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
The anxiolytic effect of Cannabidiol has a U shaped dose response curve.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Front Pharmacol. 2017 ;8:259. Epub 2017 May 11. PMID:
28553229
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Anxiety
Pharmacological Actions
:
Anti-Anxiety Agents
[+]
The findings are suggestive of a clinical effect of cannabis on incontinence episodes in patients with MS.
Oct 31, 2006
Click here to read the entire abstract
Pubmed Data
: Int Urogynecol J Pelvic Floor Dysfunct. 2006 Nov ;17(6):636-41. Epub 2006 Mar 22. PMID:
16552618
Article Published Date
: Oct 31, 2006
Study Type
: Human Study
Additional Links
Substances
:
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Incontinence
,
Multiple Sclerosis
[+]
The present study confirms the efficacy of cannabinoids in reducing spasticity in patients with multiple sclerosis.
Mar 20, 2016
Click here to read the entire abstract
Pubmed Data
: Int Clin Psychopharmacol. 2016 Mar 21. Epub 2016 Mar 21. PMID:
27003093
Article Published Date
: Mar 20, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Multiple Sclerosis
[+]
The present study suggests that THC does not selectively affect limbic regions, but rather interferes with sensory processing.
Oct 29, 2015
Click here to read the entire abstract
Pubmed Data
: Neuropsychopharmacology. 2015 Oct 30. Epub 2015 Oct 30. PMID:
26514581
Article Published Date
: Oct 29, 2015
Study Type
: Human Study
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
Diseases
:
Chronic Pain
Pharmacological Actions
:
Analgesics
[+]
The results indicate that CBD could be a useful option to treat social anxiety.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Psychol. 2019 ;10:2466. Epub 2019 Nov 8. PMID:
31787910
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Anxiety
Pharmacological Actions
:
Anti-Anxiety Agents
[+]
The results indicate that CBD could be a useful option to treat social anxiety.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Psychol. 2019 ;10:2466. Epub 2019 Nov 8. PMID:
31787910
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Anxiety
Pharmacological Actions
:
Anti-Anxiety Agents
[+]
The results reported here are very promising and indicate that CBD-enriched cannabis extract may ameliorate multiple autism spectrum disorders symptoms.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Neurol. 2019 ;10:1145. Epub 2019 Oct 31. PMID:
31736860
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Autism Spectrum Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
The results suggest that CBD may have beneficial effects on patient quality of life, distinct from its seizure-reducing effects.
Jun 14, 2017
Click here to read the entire abstract
Pubmed Data
: Epilepsia. 2017 Jun 15. Epub 2017 Jun 15. PMID:
28617940
Article Published Date
: Jun 14, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy: Childhood
,
Quality of Life: Poor
Pharmacological Actions
:
Anticonvulsants
[+]
The use of cannabidiol in patients with low back pain caused by lumbar spinal stenosis.
Aug 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cureus. 2022 Sep ;14(9):e29196. Epub 2022 Sep 15. PMID:
36507111
Article Published Date
: Aug 31, 2022
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Low Back Pain
Pharmacological Actions
:
Analgesics
[+]
These findings suggest that CBD has beneficial effects in patients with schizophrenia.
Dec 14, 2017
Click here to read the entire abstract
Pubmed Data
: Am J Psychiatry. 2017 Dec 15:appiajp201717030325. Epub 2017 Dec 15. PMID:
29241357
Article Published Date
: Dec 14, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Schizophrenia
[+]
These findings support efficacy of artisanal CBD preparations in seizure reduction with few significant side effects.
Feb 07, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Epilepsy Behav. 2018 Feb 8. Epub 2018 Feb 8. PMID:
29429908
Article Published Date
: Feb 07, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
These results confirm the clinical benefit of cannabis extracts on spastic hypertonia.
Nov 14, 2016
Click here to read the entire abstract
Pubmed Data
: J Neurol Sci. 2016 Nov 15 ;370:263-268. Epub 2016 Aug 28. PMID:
27772772
Article Published Date
: Nov 14, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Multiple Sclerosis
Additional Keywords
:
Plant Extracts
,
Significant Treatment Outcome
[+]
These results indicate that in cannabis smokers, men exhibit greater cannabis-induced analgesia relative to women.
Aug 04, 2016
Click here to read the entire abstract
Pubmed Data
: Drug Alcohol Depend. 2016 Aug 5. Epub 2016 Aug 5. PMID:
27522535
Article Published Date
: Aug 04, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Pain
Pharmacological Actions
:
Analgesics
[+]
These results reveal an immunosuppressive effect of cannabinoid preparations.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Mol Neurosci. 2017 ;10:14. Epub 2017 Jan 24. PMID:
28174520
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
Diseases
:
Inflammation
,
Pancreatitis: Chronic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Immunosuppressive Agents
Additional Keywords
:
Anti-Inflammatory Agents
,
Cannabinoids
,
Immunosuppressive Agents
,
Inflammation
,
Pancreatitis: Chronic
[+]
These results suggest that CBD has anxiolytic properties.
Jan 31, 2004
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neuropsychopharmacology. 2004 Feb ;29(2):417-26. PMID:
14583744
Article Published Date
: Jan 31, 2004
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Anxiety Disorders
Pharmacological Actions
:
Anti-Anxiety Agents
Additional Keywords
:
Anti-Anxiety Agents
,
Anxiety Disorders
,
Cannabidiol
[+]
This presents the first analysis of Italian clinical practice of the use of cannabinoids for a large variety of chronic pain syndromes.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pain Res. 2017 ;10:1217-1224. Epub 2017 May 22. PMID:
28579820
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Chronic Pain
Pharmacological Actions
:
Analgesics
[+]
This study found that cannabinoid positive patients had milder intracerebral haemorrhage presentation and less disability at discharge.
Jan 28, 2016
Click here to read the entire abstract
Pubmed Data
: Cerebrovasc Dis. 2016 Jan 29 ;41(5-6):248-255. Epub 2016 Jan 29. PMID:
26820826
Article Published Date
: Jan 28, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Stroke: Attenuation/Recovery
,
Stroke: Ischemic
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
This study may support the experimental and biological evidence for a neuroprotective effect by the endocannabinoid system in MS.
Dec 23, 2014
Click here to read the entire abstract
Pubmed Data
: J Neuroimmune Pharmacol. 2014 Dec 24. Epub 2014 Dec 24. PMID:
25537576
Article Published Date
: Dec 23, 2014
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids: Synthetic
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Multiple Sclerosis
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Dose Response
[+]
This study provides preliminary evidence supporting the self-medication theory of cannabis use in ADHD.
May 29, 2017
Click here to read the entire abstract
Pubmed Data
: Eur Neuropsychopharmacol. 2017 May 30. Epub 2017 May 30. PMID:
28576350
Article Published Date
: May 29, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Attention Deficit Hyperactivity Disorder
Additional Keywords
:
Endocannabinoid System
,
Plant Extracts
[+]
This study suggests that cannabidiol may be well tolerated as adjunctive medication for seizure management.
Feb 21, 2017
Click here to read the entire abstract
Pubmed Data
: Pediatr Neurol. 2017 Feb 22. Epub 2017 Feb 22. PMID:
28454984
Article Published Date
: Feb 21, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Seizures
,
Sturge-Weber Syndrome
Pharmacological Actions
:
Anticonvulsants
[+]
This work further confirms the anticonvulsant efficacy of CBD and supports its application in the treatment of human seizure disorders.
Jun 14, 2017
Click here to read the entire abstract
Pubmed Data
: Epilepsy Behav. 2017 Jun 15 ;73:111-118. Epub 2017 Jun 15. PMID:
28624721
Article Published Date
: Jun 14, 2017
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Seizures
Pharmacological Actions
:
Anticonvulsants
[+]
Topical 0.1% CBD reduced ulcer size and accelerated ulcer healing without side effects.
Feb 19, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Med Ther. 2023 Feb 20 ;23(1):57. Epub 2023 Feb 20. PMID:
36803360
Article Published Date
: Feb 19, 2023
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Ulcer: Aphthous
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
[+]
Treatment with THC/CBD spray appears to be a valid answer to some of the unmet needs in patients with multiple sclerosis.
Nov 25, 2015
Click here to read the entire abstract
Pubmed Data
: J Clin Pharmacol. 2015 Nov 26. Epub 2015 Nov 26. PMID:
26608223
Article Published Date
: Nov 25, 2015
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Bladder Dysfunction
,
Multiple Sclerosis
Additional Keywords
:
Plant Extracts
[+]
White matter integrity after cannabidiol administration for treatment resistant epilepsy.
Mar 07, 2021
Click here to read the entire abstract
Pubmed Data
: Epilepsy Res. 2021 Mar 8 ;172:106603. Epub 2021 Mar 8. PMID:
33725662
Article Published Date
: Mar 07, 2021
Study Type
: Human Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
[+]
Whole-plant cannabis extract can improve intractable neurogenic symptoms.
Feb 01, 2003
Click here to read the entire abstract
Pubmed Data
: Clin Rehabil. 2003 Feb;17(1):21-9. PMID:
12617376
Article Published Date
: Feb 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Marijuana
Diseases
:
Brachial Plexus Neuropathies
,
Multiple Sclerosis
,
Neurogenic Bladder
,
Phantom Limb
,
Spinal Cord Injuries
[+]
Anandamide is a potent and selective inhibitor of the proliferation of breast cancer cells.
Jul 06, 1998
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Proc Natl Acad Sci U S A. 1998 Jul 7 ;95(14):8375-80. PMID:
9653194
Article Published Date
: Jul 06, 1998
Study Type
: Human In Vitro
Additional Links
Substances
:
Anandamide
,
Cannabinoids
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Cannabinoid Receptors
,
Dose Response
[+]
Cannabidiol causes vasorelaxation of the human mesenteric artery.
Aug 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cardiovasc Res. 2015 Sep 1 ;107(4):568-78. Epub 2015 Jun 19. PMID:
26092099
Article Published Date
: Aug 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Cannabidiol
Diseases
:
Cardiovascular Diseases
Pharmacological Actions
:
Vasodilator Agents
Additional Keywords
:
Cannabinoid Receptors
[+]
Cannabidiol has anti-inflammatory effects in the acutely inflamed human colon.
Sep 26, 2017
Click here to read the entire abstract
Pubmed Data
: Clin Sci (Lond). 2017 Sep 27. Epub 2017 Sep 27. PMID:
28954820
Article Published Date
: Sep 26, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Cannabidiol
Diseases
:
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Cannabidiol has potential as a promising therapeutic agent for the treatment of acne vulgaris.
Aug 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Invest. 2014 Sep ;124(9):3713-24. Epub 2014 Jul 25. PMID:
25061872
Article Published Date
: Aug 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Cannabidiol
Diseases
:
Acne
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Cannabidiol induces autophagy via ERK1/2 activation in neural cells.
Mar 07, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2021 Mar 8 ;11(1):5434. Epub 2021 Mar 8. PMID:
33686185
Article Published Date
: Mar 07, 2021
Study Type
: Human In Vitro
Additional Links
Substances
:
Cannabidiol
Diseases
:
Neurodegenerative Diseases
Pharmacological Actions
:
Autophagy Up-regulation
,
Neuroprotective Agents
[+]
Cannabidiol protects adipose-derived mesenchymal stem cells against endoplasmic reticulum stress.
Aug 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Environ Res Public Health. 2022 Aug 31 ;19(17). Epub 2022 Aug 31. PMID:
36078578
Article Published Date
: Aug 30, 2022
Study Type
: Human In Vitro
Additional Links
Substances
:
Cannabidiol
Diseases
:
Metabolic Diseases
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis.
Dec 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2011 ;6(12):e28159. Epub 2011 Dec 6. PMID:
22163000
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Cannabidiol
Diseases
:
Inflammation
,
Inflammatory Bowel Diseases
,
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
CBD improved alcohol-induced hepatic metabolic dysregulation and steatosis.
Sep 20, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Sep 21 ;7(1):12064. Epub 2017 Sep 21. PMID:
28935932
Article Published Date
: Sep 20, 2017
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Cannabidiol
Diseases
:
Alcoholic Liver Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hypolipidemic
[+]
Data suggest that activity at the BBB could represent an as yet unrecognised mechanism of CBD-induced neuroprotection in ischaemic stroke
Oct 23, 2015
Click here to read the entire abstract
Pubmed Data
: Br J Pharmacol. 2015 Oct 24. Epub 2015 Oct 24. PMID:
26497782
Article Published Date
: Oct 23, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Cannabidiol
Diseases
:
Stroke: Attenuation/Recovery
,
Stroke: Ischemic
Pharmacological Actions
:
Neuroprotective Agents
,
Vascular Cell Adhesion Molecule-1 Inhibitor
Additional Keywords
:
Blood Brain Barrier
[+]
Human skin permeation of Delta8-tetrahydrocannabinol, cannabidiol and cannabinol.
Feb 29, 2004
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharmacol. 2004 Mar ;56(3):291-7. PMID:
15025853
Article Published Date
: Feb 29, 2004
Study Type
: Human In Vitro
Additional Links
Substances
:
Cannabidiol
,
Cannabinoids
[+]
Phytocannabinoids could be efficient and safe novel treatments in the management of cutaneous inflammations.
Apr 19, 2016
Click here to read the entire abstract
Pubmed Data
: Exp Dermatol. 2016 Apr 20. Epub 2016 Apr 20. PMID:
27094344
Article Published Date
: Apr 19, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Cannabidiol
,
Cannabidivarin
,
Cannabigerol
,
Cannabigerovarin
,
Cannabinoids
Diseases
:
Acne
,
Dry Skin
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
THC exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease.
Sep 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neuropathol Appl Neurobiol. 2012 Oct ;38(6):535-47. PMID:
22236282
Article Published Date
: Sep 30, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
Diseases
:
Oxidative Stress
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
THC inhibited cell proliferation, migration and invasion, and induced cell apoptosis in cholangiocarcinoma cells.
Apr 30, 2010
Click here to read the entire abstract
Pubmed Data
: Cancer Invest. 2010 May ;28(4):357-63. PMID:
19916793.
Article Published Date
: Apr 30, 2010
Study Type
: Human In Vitro
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
Diseases
:
Cancer Metastasis
,
Cholangiocarcinoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Dose Response
[+]
The present data suggest that targeting CB(1)/CB(2) may have therapeutic potential for the treatment of mantle cell lymphoma.
Oct 31, 2006
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Pharmacol. 2006 Nov ;70(5):1612-20. Epub 2006 Aug 25. PMID:
16936228
Article Published Date
: Oct 31, 2006
Study Type
: Human In Vitro
Additional Links
Substances
:
Cannabinoids
,
Cannabinoids: Synthetic
Diseases
:
Lymphoma
Pharmacological Actions
:
Apoptotic
,
P38 Mitogen-Activated Protein Kinase Modulator
Additional Keywords
:
Selective Cytotoxicity
[+]
The proapoptotic effect of cannabinoids on tumor cells is mediated by a ceramide dependent upregulation of the stress protein p8.
Mar 31, 2006
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Cell. 2006 Apr ;9(4):301-12. PMID:
16616335
Article Published Date
: Mar 31, 2006
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Cannabinoids
Diseases
:
Astrocytoma
,
Cancers: All
,
Glioblastoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Altered Protein Expression
,
Gene Expression Regulation
[+]
These findings describe a mechanism by which THC can promote the autophagic death of human and mouse cancer cells.
Apr 30, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Invest. 2009 May ;119(5):1359-72. PMID:
19425170
Article Published Date
: Apr 30, 2009
Study Type
: Animal Study, Human In Vitro, In Vitro Study
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
Diseases
:
Glioblastoma Multiforme
,
Glioma
Pharmacological Actions
:
Apoptotic
,
Autophagy Up-regulation
,
Enzyme Inhibitors
[+]
All three patients reported improved pain scores, reduced pruritus and reduction in overall analgesic drug intake.
Oct 21, 2018
Click here to read the entire abstract
Pubmed Data
: Br J Dermatol. 2018 Oct 22. Epub 2018 Oct 22. PMID:
30347109
Article Published Date
: Oct 21, 2018
Study Type
: Human: Case Report
Additional Links
Substances
:
Cannabidiol
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Epidermolysis Bullosa
Pharmacological Actions
:
Analgesics
Additional Keywords
:
Medication Reduction
[+]
Report of a 6-month-old Asian infant with early infantile epileptic encephalopathy whose seizures were eliminated by cannabidiol.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Epilepsy Behav Rep. 2020 ;14:100373. Epub 2020 Jun 8. PMID:
32695984
Article Published Date
: Dec 31, 2019
Study Type
: Human: Case Report
Additional Links
Substances
:
Cannabidiol
Diseases
:
Encephalopathy
,
Epilepsy
Pharmacological Actions
:
Anticonvulsants
Additional Keywords
:
Significant Treatment Outcome
[+]
A 10-month-old boy with malignant migrating partial seizures in infancy made developmental gains and sustained seizure reduction with the addition of cannabidiol to his antiepileptic regimen.
Apr 30, 2015
Click here to read the entire abstract
Pubmed Data
: Pediatr Neurol. 2015 May ;52(5):544-7. Epub 2015 Feb 19. PMID:
25882081
Article Published Date
: Apr 30, 2015
Study Type
: Human: Case Report
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy: Infant
,
Epilepsy: Malignant Migrating Partial Seizures
Pharmacological Actions
:
Anticonvulsants
[+]
A case of oral Delta 9-tetrahydrocannabinol (THC) improving refractory Gilles de la Tourette Syndrome and comordid ADHD has been reported.
Apr 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Clin Psychopharmacol. 2010 Apr;30(2):190-2. PMID:
20520294
Article Published Date
: Apr 01, 2010
Study Type
: Human: Case Report
Additional Links
Substances
:
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Attention Deficit Disorder with Hyperactivity
,
Tourette Syndrome
[+]
A case report of the clinical outcome and image response of two patients with secondary high-grade glioma.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Oncol. 2018 ;8:643. Epub 2019 Jan 18. PMID:
30713832
Article Published Date
: Dec 31, 2017
Study Type
: Human: Case Report
Additional Links
Substances
:
Cannabidiol
Diseases
:
Glioma
Pharmacological Actions
:
Chemotherapeutic
[+]
Cannabidiol Has Potential As A Treatment for Febrile Infection-Related Epilepsy Syndrome (FIRES) in the Acute and Chronic Phases.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: J Child Neurol. 2017 Jan ;32(1):35-40. Epub 2016 Sep 29. PMID:
27655472
Article Published Date
: Dec 31, 2016
Study Type
: Human: Case Report
Additional Links
Substances
:
Cannabidiol
Diseases
:
Febrile Seizures
[+]
Cannabidiol in treatment of autism spectrum disorder: A case study.
Jul 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cureus. 2022 Aug ;14(8):e28442. Epub 2022 Aug 26. PMID:
36176817
Article Published Date
: Jul 31, 2022
Study Type
: Human: Case Report
Additional Links
Substances
:
Cannabidiol
Diseases
:
Autism Spectrum Disorders
[+]
Cannabidiol oil could be used as a safe treatment for reducing anxiety and improving sleep in posttraumatic stress disorders.
Oct 11, 2016
Click here to read the entire abstract
Pubmed Data
: Perm J. 2016 Oct 12 ;20(4). Epub 2016 Aug 12. PMID:
27768570
Article Published Date
: Oct 11, 2016
Study Type
: Human: Case Report
Additional Links
Substances
:
Cannabidiol
Diseases
:
Anxiety Disorders
,
Insomnia
,
Post-Traumatic Stress Disorders (PTSD)
Pharmacological Actions
:
Anti-Anxiety Agents
[+]
Cannabinoids are a safe and effective treatment for Tourette syndrome and should be considered in treatment-resistant cases.
Aug 23, 2016
Click here to read the entire abstract
Pubmed Data
: Australas Psychiatry. 2016 Aug 24. Epub 2016 Aug 24. PMID:
27558217
Article Published Date
: Aug 23, 2016
Study Type
: Human: Case Report
Additional Links
Substances
:
Cannabidiol
,
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Tourette Syndrome
Additional Keywords
:
Plant Extracts
[+]
Cannabinoids inhibit glioma (brain cancer) through the down-regulation of Tissue Inhibitors of Metalloproteinases (TIMPs).
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Neuropharmacology. 2008 Jan;54(1):235-43. Epub 2007 Jul 1. PMID:
17675107
Article Published Date
: Jan 01, 2008
Study Type
: Human: Case Report, In Vitro Study
Additional Links
Substances
:
Cannabinoids
,
Marijuana
Diseases
:
Astrocytoma
,
Astrocytoma: Grade IV
,
Brain Cancer
,
Glioma
Additional Keywords
:
Tissue Inhibitors of Metalloproteinases (TIMPs)
[+]
Cutaneous squamous cell carcinoma and Lichen simplex chronicus successfully treated with topical cannabinoid oil.
Mar 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cureus. 2022 Apr ;14(4):e23850. Epub 2022 Apr 5. PMID:
35530920
Article Published Date
: Mar 31, 2022
Study Type
: Human: Case Report
Additional Links
Substances
:
Cannabidiol
Diseases
:
Lichenoid Dermatitis
,
Squamous cell carcinoma
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
[+]
Four patients treated with CBD had prompt and substantial reduction in the frequency of REM sleep behaviour disorder related events without side effects.
Sep 30, 2014
Click here to read the entire abstract
Pubmed Data
: J Clin Pharm Ther. 2014 Oct ;39(5):564-6. Epub 2014 May 21. PMID:
24845114
Article Published Date
: Sep 30, 2014
Study Type
: Human: Case Report
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Sleep Disorders
Additional Keywords
:
Phytotherapy
,
Significant Treatment Outcome
[+]
Further research may be appropriate to elucidate the increasingly recognized effect of cannabis/cannabinoids on gliomas.
Mar 31, 2011
Click here to read the entire abstract
Pubmed Data
: Childs Nerv Syst. 2011 Apr ;27(4):671-9. Epub 2011 Feb 20. PMID:
21336992
Article Published Date
: Mar 31, 2011
Study Type
: Human: Case Report
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Glioma
Additional Keywords
:
Cannabinoids
,
Cannabis
,
Glioma
,
Spontaneous Tumor Regression
[+]
Potential role of cannabidiol for seizure control in a patient with recurrent glioma.
Dec 13, 2019
Click here to read the entire abstract
Pubmed Data
: J Clin Neurosci. 2019 Dec 14. Epub 2019 Dec 14. PMID:
31848037
Article Published Date
: Dec 13, 2019
Study Type
: Human: Case Report
Additional Links
Substances
:
Cannabidiol
Diseases
:
Glioma
,
Seizures
Pharmacological Actions
:
Anticonvulsants
,
Chemotherapeutic
[+]
Successful use of pure cannabidiol for the treatment of super-refractory status epilepticus.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Epilepsy Behav Case Rep. 2018 ;10:141-144. Epub 2018 Jul 17. PMID:
30596011
Article Published Date
: Dec 31, 2017
Study Type
: Human: Case Report
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
THC combined with CBD led to a rapid and highly significant improvement in a patient with Tourette syndrome.
Jul 29, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Psychiatry Med. 2018 Jul 30:91217418791455. Epub 2018 Jul 30. PMID:
30058466
Article Published Date
: Jul 29, 2018
Study Type
: Human: Case Report
Additional Links
Substances
:
Cannabidiol
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Tourette Syndrome
[+]
The data presented here may indicate that CBD led to a partial tumour response in a patient with histologically proven adenocarcinoma of the lung.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: SAGE Open Med Case Rep. 2019 ;7:2050313X19832160. Epub 2019 Feb 21. PMID:
30815264
Article Published Date
: Dec 31, 2018
Study Type
: Human: Case Report, Review
Additional Links
Substances
:
Cannabidiol
Diseases
:
Lung Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Immunomodulatory
[+]
These cases support pre-clinical and preliminary clinical evidence suggesting that CBD may be effective for some patients with epilepsy.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2016 ;7:359. Epub 2016 Aug 30. PMID:
27746737
Article Published Date
: Dec 31, 2015
Study Type
: Human: Case Report
Additional Links
Substances
:
Cannabidiol
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Epilepsy: Childhood
Pharmacological Actions
:
Anticonvulsants
[+]
CBD exhibits anti-seizure properties in acute seizure models.
May 05, 2017
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2017 May 6. Epub 2017 May 6. PMID:
28478594
Article Published Date
: May 05, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
Insights on cannabidiol's antiallodynic and anxiolytic mechanisms of action in a model of neuropathic pain.
Aug 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pain Rep. 2019 Sep-Oct;4(5):e774. Epub 2019 Aug 13. PMID:
32766463
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Neuropathic Pain
Pharmacological Actions
:
Anti-Anxiety Agents
,
Antinoceceptive
[+]
Δ9-Tetrahydrocannabinolic Acid markedly alleviates liver fibrosis and inflammation.
Nov 29, 2020
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2020 Nov 30 ;81:153426. Epub 2020 Nov 30. PMID:
33341026
Article Published Date
: Nov 29, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Inflammation
,
Liver Fibrosis
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
A cannabigerol enriched cannabis extract could be used as an appetite stimulant.
Jan 24, 2017
Click here to read the entire abstract
Pubmed Data
: Behav Pharmacol. 2017 Jan 25. Epub 2017 Jan 25. PMID:
28125508
Article Published Date
: Jan 24, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Appetite Disorders: Loss/Lack of
Pharmacological Actions
:
Appetite Stimulants
Additional Keywords
:
Plant Extracts
[+]
A cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis.
Aug 07, 2006
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2006 Aug 7;542(1-3):100-5. Epub 2006 May 20. PMID:
16781706
Article Published Date
: Aug 07, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Cannabinoids
Diseases
:
Amyotrophic Lateral Sclerosis
Pharmacological Actions
:
Neuroprotective Agents
[+]
A cannabis extract with high content in cannabidiol attenuated chemically-induced intestinal inflammation.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2016 ;7:341. Epub 2016 Aug 4. PMID:
27757083
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Cannabinoids
,
Cannabis
Diseases
:
Colitis
,
Gastrointestinal Inflammation
,
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
A chronic low dose of Δ9-tetrahydrocannabinol (THC) restores cognitive function in old mice.
May 07, 2017
Click here to read the entire abstract
Pubmed Data
: Nat Med. 2017 May 8. Epub 2017 May 8. PMID:
28481360
Article Published Date
: May 07, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
Diseases
:
Aging: Brain
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Cannabinoid Receptors
[+]
A combination of Cannabichromene and Delta-tetrahydrocannabinol leads to enhanced tetrad and anti-inflammatory actions.
Oct 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Alcohol Depend. 2010 Nov 1 ;112(1-2):126-33. PMID:
20619971
Article Published Date
: Oct 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
A nanoformulation of THC revealed a statistically significant selective cytotoxic effect towards lung cancer cell lines.
Jun 19, 2015
Click here to read the entire abstract
Pubmed Data
: Int J Pharm. 2015 Jun 20 ;487(1-2):205-12. Epub 2015 Apr 18. PMID:
25899283
Article Published Date
: Jun 19, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
Diseases
:
Lung Cancer
Pharmacological Actions
:
Cytotoxic
Additional Keywords
:
Nanoparticles
,
Selective Cytotoxicity
[+]
A single ultra-low dose of THC before ischemia is a safe and effective treatment that reduces myocardial ischemic damage.
May 31, 2013
Click here to read the entire abstract
Pubmed Data
: Biochem Pharmacol. 2013 Jun 1 ;85(11):1626-33. Epub 2013 Mar 26. PMID:
23537701
Article Published Date
: May 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Cannabinoids
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Myocardial Infarction
,
Myocardial Ischemia
Pharmacological Actions
:
Cardioprotective
,
Neuroprotective Agents
[+]
A synthetic cannabinoid inhibited CXCL12-induced migration and invasive properties of breast cancer cells.
Dec 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2011 ;6(9):e23901. Epub 2011 Sep 7. PMID:
21915267
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cannabinoids
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
Additional Keywords
:
Cannabinoid Receptors
,
Synthetic Cannabinoids
[+]
Abnormal cannabidiol ameliorates inflammation preserving pancreatic beta cells.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2022 Jan ;145:112361. Epub 2021 Dec 3. PMID:
34872800
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Diabetes Mellitus: Type 1
Pharmacological Actions
:
Pancreato Protective Agents
[+]
Activation of cannabinoid receptors could be a new therapeutic approach for the treatment of skin tumors.
Dec 31, 2002
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Invest. 2003 Jan ;111(1):43-50. PMID:
12511587
Article Published Date
: Dec 31, 2002
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cannabinoids
Diseases
:
Skin Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Antineoplastic Agents
,
Apoptotic
,
Vascular Endothelial Growth Factor A Inhibitor
,
Vascular Endothelial Growth Factor Regulator
Additional Keywords
:
Cannabinoid Receptors
[+]
Activation of cannabinoid system may have protective actions on both liver and brain induced by cocaine, minimizing inflammatory injury promoted by cocaine.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2015 ;2015:523418. Epub 2015 Apr 27. PMID:
25999668
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Cocaine Toxicity
,
Drug Abuse
Pharmacological Actions
:
Hepatoprotective
,
Neuroprotective Agents
[+]
Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion.
Jul 01, 2010
Click here to read the entire abstract
Pubmed Data
: Br J Pharmacol. 2010 Jul;160(5):1234-42. PMID:
20590615
Article Published Date
: Jul 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Cardiac Arrhythmias
,
Myocardial Infarction
,
Myocardial Ischemia
Pharmacological Actions
:
Cardioprotective
[+]
Administration of synthetic 2-AG to mice after CHI led to significant reduction of brain oedema, better clinical recovery, reduced infarct volume and reduced hippocampal cell death compared with controls.
Oct 03, 2001
Click here to read the entire abstract
Pubmed Data
: Nature. 2001 Oct 4 ;413(6855):527-31. PMID:
11586361
Article Published Date
: Oct 03, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Cannabinoids
,
Endocannabinoids
Diseases
:
Brain Edema
,
Brain Inflammation
,
Traumatic Brain Injury
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
Additional Keywords
:
Significant Treatment Outcome
[+]
Administration of THC was observed to enhance the neurogenesis in the brain
Sep 20, 2017
Click here to read the entire abstract
Pubmed Data
: Neurotox Res. 2017 Sep 21. Epub 2017 Sep 21. PMID:
28933048
Article Published Date
: Sep 20, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
Diseases
:
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neurogenesis
[+]
Amphirregulin is a factor for resistance of glioma cells to THC-induced apoptosis.
Sep 30, 2009
Click here to read the entire abstract
Pubmed Data
: Glia. 2009 Oct ;57(13):1374-85. PMID:
19229996
Article Published Date
: Sep 30, 2009
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
Diseases
:
Gliomas
Pharmacological Actions
:
Antineoplastic Agents
,
Apoptotic
[+]
Analgesic and anti-inflammatory effects of 1% topical cannabidiol gel in animal models.
Sep 04, 2023
Click here to read the entire abstract
Pubmed Data
: Cannabis Cannabinoid Res. 2023 Sep 5. Epub 2023 Sep 5. PMID:
37669453
Article Published Date
: Sep 04, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Inflammation
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
[+]
Antiapoptotic effects of cannabidiol in an experimental model of cognitive decline induced by brain iron overload.
Sep 02, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Transl Psychiatry. 2018 Sep 3 ;8(1):176. Epub 2018 Sep 3. PMID:
30177808
Article Published Date
: Sep 02, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Cognitive Decline/Dysfunction
,
Iron Overload
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Anticonvulsant and neuroprotective effects of cannabidiol during the juvenile period.
Aug 27, 2018
Click here to read the entire abstract
Pubmed Data
: J Neuropathol Exp Neurol. 2018 Aug 28. Epub 2018 Aug 28. PMID:
30169677
Article Published Date
: Aug 27, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
Anticonvulsive properties of cannabidiol in a model of generalized seizure are transient receptor potential vanilloid 1 dependent.
May 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cannabis Cannabinoid Res. 2020 Jun 1 ;5(2):145-149. Epub 2020 Jun 5. PMID:
32656346
Article Published Date
: May 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Lennox-Gastaut Syndrome
Pharmacological Actions
:
Anticonvulsants
[+]
Antidepressant-like effect induced by cannabidiol is dependent on brain serotonin levels.
Jun 05, 2018
Click here to read the entire abstract
Pubmed Data
: Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jun 6. Epub 2018 Jun 6. PMID:
29885468
Article Published Date
: Jun 05, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
[+]
Antinociceptive and anti-inflammatory properties of cannabidiol alone and in combination with standardized bioflavonoid composition.
Feb 09, 2021
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2021 Feb 10. Epub 2021 Feb 10. PMID:
33570460
Article Published Date
: Feb 09, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Bioflavonoids
,
Cannabidiol
Diseases
:
Chronic Pain
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antinoceceptive
[+]
Antitumor effects of cannabinoids in human pancreatic ductal adenocarcinoma cell line.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Vet Sci. 2022 ;9:867575. Epub 2022 Jul 22. PMID:
35937289
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Cannabinoids
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Avidekel cannabis extracts and cannabidiol are as efficient as copaxone in suppressing experimental autoimmune encephalomyelitis in mice.
Oct 04, 2018
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2018 Oct 5. Epub 2018 Oct 5. PMID:
30291491
Article Published Date
: Oct 04, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Multiple Sclerosis
Pharmacological Actions
:
Immunomodulatory
Additional Keywords
:
Natural Substances Versus Drugs
[+]
Cannabichromene could be considered for clinical experimentation in inflammatory bowel disease patients.
Apr 30, 2013
Click here to read the entire abstract
Pubmed Data
: Biochem Pharmacol. 2013 May 1 ;85(9):1306-16. Epub 2013 Feb 12. PMID:
23415610
Article Published Date
: Apr 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Cannabigerol
,
Cannabinoids
Diseases
:
Colitis
,
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 downregulation
,
Interleukin-1 beta downregulation
,
Nitric Oxide Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Cannabichromene raises the viability of NSPCs while inhibiting their differentiation into astroglia.
Oct 31, 2013
Click here to read the entire abstract
Pubmed Data
: Neurochem Int. 2013 Nov ;63(5):432-7. Epub 2013 Aug 11. PMID:
23941747
Article Published Date
: Oct 31, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cannabinoids
Additional Keywords
:
Neural Stem Cells
[+]
Cannabichromene selectively reduces inflammation-induced hypermotility in vivo.
May 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Pharmacol. 2012 Jun ;166(4):1444-60. PMID:
22300105
Article Published Date
: May 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Cannabidiol acts in the dorsal striatum to improve haloperidol-induced catalepsy.
Apr 26, 2016
Click here to read the entire abstract
Pubmed Data
: Behav Brain Res. 2016 Apr 27 ;309:22-28. Epub 2016 Apr 27. PMID:
27131780
Article Published Date
: Apr 26, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Pharmacological Actions
:
Neuroprotective Agents
Problem Substances
:
Antipsychotic Drugs
[+]
Cannabidiol administration after hypoxia-ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function.
Sep 30, 2012
Click here to read the entire abstract
Pubmed Data
: Neuropharmacology. 2012 Oct ;63(5):776-83. Epub 2012 May 30. PMID:
22659086
Article Published Date
: Sep 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Brain Damage: Hypoxic Ischemic Insult
,
Brain Ischemia
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cannabidiol alleviates right ventricular fibrosis by inhibiting the transforming growth factor β pathway.
Jul 31, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biochim Biophys Acta Mol Basis Dis. 2023 Aug ;1869(6):166753. Epub 2023 May 13. PMID:
37187449
Article Published Date
: Jul 31, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Heart Failure
,
Hypertension: Pulmonary
,
Myocardial Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Transforming growth factor beta (TGF-β) inhibitor
[+]
Cannabidiol ameliorates cognitive function via regulation of IL-33 and TREM2 upregulation.
Feb 16, 2021
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2021 Feb 17. Epub 2021 Feb 17. PMID:
33612548
Article Published Date
: Feb 16, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cannabidiol ameliorates inflammatory response partly by AGE-RAGE pathway in diabetic mice.
Oct 31, 2023
Click here to read the entire abstract
Pubmed Data
: Drug Dev Res. 2023 Nov ;84(7):1427-1436. Epub 2023 Jul 24. PMID:
37486107
Article Published Date
: Oct 31, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Diabetic Complications
,
Hyperglycemia
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hypoglycemic Agents
,
Interleukin-1 beta downregulation
[+]
Cannabidiol ameliorates monocrotaline-induced pulmonary hypertension in rats.
Sep 24, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2020 Sep 25 ;21(19). Epub 2020 Sep 25. PMID:
32992900
Article Published Date
: Sep 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Hypertension: Pulmonary
Pharmacological Actions
:
Antihypertensive Agents
[+]
Cannabidiol ameliorates the anxiogenic and compulsive-like behaviors induced by chronic consumption of a high-carbohydrate diet.
Aug 29, 2022
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2022 Aug 30. Epub 2022 Aug 30. PMID:
36040711
Article Published Date
: Aug 29, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Obesity
,
Psychiatric Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Anti-Obesity Agents
[+]
Cannabidiol and abnormal cannabidiol reduced the infarct volume.
Apr 30, 2005
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Stroke. 2005 May ;36(5):1077-82. Epub 2005 Apr 21. PMID:
15845890
Article Published Date
: Apr 30, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Middle Cerebral Artery Occlusion (MCAO)
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Cannabidiol
,
Middle Cerebral Artery Occlusion (MCAO)
,
Neuroprotective Agents
[+]
Cannabidiol and beta-caryophyllene in combination: A therapeutic functional interaction.
Dec 06, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2022 Dec 7 ;23(24). Epub 2022 Dec 7. PMID:
36555111
Article Published Date
: Dec 06, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Beta-Caryophyllene
,
Cannabidiol
,
Cannabinoids
,
Cannabis
Diseases
:
Chronic Pain
Pharmacological Actions
:
Analgesics
Additional Keywords
:
Natural Substance Synergy
[+]
Cannabidiol and cannabigerol, non-psychotropic cannabinoids, as analgesics that effectively manage bone fracture pain and promote healing.
Aug 18, 2023
Click here to read the entire abstract
Pubmed Data
: J Bone Miner Res. 2023 Aug 19. Epub 2023 Aug 19. PMID:
37597163
Article Published Date
: Aug 18, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Cannabigerol
Diseases
:
Bone Fractures
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
[+]
Cannabidiol anticonvulsant effect is mediated by the PI3Kγ pathway.
Jun 19, 2020
Click here to read the entire abstract
Pubmed Data
: Neuropharmacology. 2020 Jun 20:108156. Epub 2020 Jun 20. PMID:
32574650
Article Published Date
: Jun 19, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
Cannabidiol antidepressant-like effect in the lipopolysaccharide model in mice: modulation of inflammatory pathways.
Jan 25, 2021
Click here to read the entire abstract
Pubmed Data
: Biochem Pharmacol. 2021 Jan 26:114433. Epub 2021 Jan 26. PMID:
33513342
Article Published Date
: Jan 25, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-6 Downregulation
[+]
Cannabidiol attenuates behavioral changes in a rodent model of schizophrenia through 5-HT1A, but not CB1 and CB2 receptors.
Mar 05, 2020
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2020 Mar 6 ;156:104749. Epub 2020 Mar 6. PMID:
32151683
Article Published Date
: Mar 05, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Schizophrenia
Pharmacological Actions
:
Antidepressive Agents
[+]
Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy.
Dec 14, 2010
Click here to read the entire abstract
Pubmed Data
: J Am Coll Cardiol. 2010 Dec 14;56(25):2115-25. PMID:
21144973
Article Published Date
: Dec 14, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Cardiomyopathy
,
Cardiovascular Diseases
,
Diabetes: Cardiovascular Illness
[+]
Cannabidiol attenuates delayed-type hypersensitivity reactions.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Acta Pharmacol Sin. 2010 Dec;31(12):1611-7. Epub 2010 Nov 1. PMID:
21042286
Article Published Date
: Dec 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Hypersensitivity
,
Hypersensitivity: Type IV
[+]
Cannabidiol attenuates hypersensitivity and oxidative stress after traumatic spinal cord injury.
Jan 24, 2022
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2022 09 25 ;788:136855. Epub 2022 Aug 23. PMID:
36028005
Article Published Date
: Jan 24, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Oxidative Stress
,
Spinal Cord Injuries
Pharmacological Actions
:
Analgesics
,
Antioxidants
[+]
Cannabidiol attenuates mechanical allodynia in streptozotocin-induced diabeties.
Mar 17, 2019
Click here to read the entire abstract
Pubmed Data
: Brain Res. 2019 Mar 18. Epub 2019 Mar 18. PMID:
30898678
Article Published Date
: Mar 17, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Allodynia
,
Diabetic Neuropathy
Pharmacological Actions
:
Analgesics
[+]
Cannabidiol attenuates MK-80-induced cognitive smptoms of schizophrenia in the passive avoidance test.
Oct 01, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2021 Oct 2 ;26(19). Epub 2021 Oct 2. PMID:
34641522
Article Published Date
: Oct 01, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Memory Disorders
,
Schizophrenia
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cannabidiol attenuates seizures and EEG abnormalities in Angelman syndrome model mice.
Sep 09, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Invest. 2019 Sep 10. Epub 2019 Sep 10. PMID:
31503547
Article Published Date
: Sep 09, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Angelman Syndrome
,
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome.
Oct 01, 2017
Click here to read the entire abstract
Pubmed Data
: Proc Natl Acad Sci U S A. 2017 Oct 2. Epub 2017 Oct 2. PMID:
28973916
Article Published Date
: Oct 01, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Autism
,
Dravet syndrome
,
Seizures
Pharmacological Actions
:
Anticonvulsants
[+]
Cannabidiol blocks opioid reward suggests that this compound may be useful in addiction treatment settings.
Aug 08, 2017
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2017 Aug 9. Epub 2017 Aug 9. PMID:
28793355
Article Published Date
: Aug 08, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Morphine Tolerance/Dependence
[+]
Cannabidiol can possibly be used as a therapeutic agent for treatment of type 1 diabetes.
Dec 31, 2007
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neuropharmacology. 2008 Jan ;54(1):244-9. Epub 2007 Jul 17. PMID:
17714746
Article Published Date
: Dec 31, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Diabetes Mellitus: Type 1: Prevention
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
,
Interleukin-12 downregulation
[+]
cannabidiol confers cardioprotection in diabetic rats independent of glycemic control.
Dec 19, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2017 Dec 20 ;820:256-264. Epub 2017 Dec 20. PMID:
29274332
Article Published Date
: Dec 19, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Diabetic Complications
Pharmacological Actions
:
Cardioprotective
[+]
Cannabidiol confers neuroprotection in a model of transient global cerebral ischemia.
Jul 23, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Neurobiol. 2021 Jul 24. Epub 2021 Jul 24. PMID:
34302281
Article Published Date
: Jul 23, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cannabidiol controls the exaggerated inflammatory response observed in an animal model of asthma.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2015 ;2015:538670. Epub 2015 May 25. PMID:
26101464
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Asthma
Pharmacological Actions
:
Anti-Inflammatory Agents
,
interleukin-13 down-regulation
,
Interleukin-4 downregulation
,
Interleukin-5 downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cannabidiol could be used to prevent experimental colitis in mice.
Oct 31, 2009
Click here to read the entire abstract
Pubmed Data
: J Mol Med (Berl). 2009 Nov ;87(11):1111-21. Epub 2009 Aug 20. PMID:
19690824
Article Published Date
: Oct 31, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Colitis
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-10 downregulation
,
Interleukin-1 beta downregulation
[+]
Cannabidiol could represent a novel fast antidepressant drug, via enhancing both serotonergic and glutamate cortical signalling.
Dec 18, 2015
Click here to read the entire abstract
Pubmed Data
: Neuropharmacology. 2015 Dec 19. Epub 2015 Dec 19. PMID:
26711860
Article Published Date
: Dec 18, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
[+]
Cannabidiol decreases intestinal inflammation in the ovariectomized murine model of postmenopause.
Dec 27, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomedicines. 2022 Dec 28 ;11(1). Epub 2022 Dec 28. PMID:
36672582
Article Published Date
: Dec 27, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Inflammation
,
Postmenopausal Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Cannabidiol disrupts conditioned fear expression and cannabidiolic acid reduces trauma-induced anxiety-related behaviour.
May 28, 2020
Click here to read the entire abstract
Pubmed Data
: Behav Pharmacol. 2020 May 29. Epub 2020 May 29. PMID:
32483052
Article Published Date
: May 28, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Anxiety
Pharmacological Actions
:
Anti-Anxiety Agents
[+]
Cannabidiol disrupts the consolidation of specific and generalized fear memories.
Jul 24, 2017
Click here to read the entire abstract
Pubmed Data
: Neuropharmacology. 2017 Jul 25. Epub 2017 Jul 25. PMID:
28754373
Article Published Date
: Jul 24, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Traumatic Memory Formation
[+]
Cannabidiol does not display drug abuse potential in mice behavior.
Jul 17, 2018
Click here to read the entire abstract
Pubmed Data
: Acta Pharmacol Sin. 2018 Jul 18. Epub 2018 Jul 18. PMID:
30022153
Article Published Date
: Jul 17, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Psychiatric Disorders
Additional Keywords
:
Safety of Natural Substances
[+]
Cannabidiol effect in pentylenetetrazole-induced seizures depends on PI3K.
Sep 15, 2022
Click here to read the entire abstract
Pubmed Data
: Pharmacol Rep. 2022 Sep 16. Epub 2022 Sep 16. PMID:
36112318
Article Published Date
: Sep 15, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
Pharmacological Actions
:
Anticonvulsants
[+]
Cannabidiol enhanced the ability of THC to inhibit cell proliferation, induce cell cycle arrest and apoptosis.
Dec 31, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Cancer Ther. 2010 Jan ;9(1):180-9. Epub 2010 Jan 6. PMID:
20053780
Article Published Date
: Dec 31, 2009
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cannabidiol
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Cancer Metastasis
,
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
Additional Keywords
:
Cannabinoid Receptors
,
Natural Substance Synergy
[+]
Cannabidiol enhanced the hippocampal immune response and autophagy of APP/PS1 Alzheimer's mice.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2021 Jan 1 ;264:118624. Epub 2020 Oct 21. PMID:
33096116
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Immunostimulatory
,
Neuroprotective Agents
[+]
Cannabidiol enhances cytotoxicity of anti-cancer drugs in human head and neck squamous cell carcinoma.
Jan 25, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2020 11 26 ;10(1):20622. Epub 2020 Nov 26. PMID:
33244087
Article Published Date
: Jan 25, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Head and Neck Cancer
Pharmacological Actions
:
Apoptotic
,
Chemosensitizer
Additional Keywords
:
Chemothapeutic Synergy: 5-flourouracil
,
Chemothapeutic Synergy: Paclitaxel
,
Chemotherapeutic Synergy: Cisplatin
[+]
Cannabidiol enhances the antinociceptive effects of morphine and attenuates opioid-induced tolerance in the chronic constriction injury model.
Oct 27, 2022
Click here to read the entire abstract
Pubmed Data
: Behav Brain Res. 2022 Oct 28 ;435:114076. Epub 2022 Aug 24. PMID:
36028000
Article Published Date
: Oct 27, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Morphine Tolerance/Dependence
Pharmacological Actions
:
Analgesics
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Cannabidiol exhibits an anticonvulsive effect in the rats with chronic epilepsy.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Clin Exp Med. 2015 ;8(6):8820-7. Epub 2015 Jun 15. PMID:
26309534
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Epilepsy
,
Epilepsy: Drug-Induced
Pharmacological Actions
:
Anticonvulsants
,
Neuroprotective Agents
[+]
Cannabidiol exhibits an antipsychotic-like profile without inducing extrapyramidal-like effects.
Apr 10, 2005
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2005 Apr 11 ;512(2-3):199-205. PMID:
15840405
Article Published Date
: Apr 10, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Pharmacological Actions
:
Antipsychotic Agents
Additional Keywords
:
Antipsychotic Agents
,
Cannabidiol
,
Natural Substances Versus Drugs
[+]
Cannabidiol exhibits therapeutic activity in a mouse model of obsessive-compulsive disorder.
Feb 01, 2006
Click here to read the entire abstract
Pubmed Data
: Platelets. 2006 Feb;17(1):37-41. PMID:
20695034
Article Published Date
: Feb 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Obsessive-Compulsive Disorder
[+]
Cannabidiol exhibits therapeutic potential against ischemia/reperfusion liver injury in rats.
Nov 16, 2011
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2011 Nov 16 ;670(1):216-23. Epub 2011 Sep 14. PMID:
21930120
Article Published Date
: Nov 16, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Liver Damage
,
Liver Injury: Ischemia/reperfusion
Pharmacological Actions
:
Hepatoprotective
[+]
Cannabidiol has a neuroprotective and blood-retinal-preserving effect in experimental diabetes.
Jan 01, 2004
Click here to read the entire abstract
Pubmed Data
: Int Urol Nephrol. 2004;36(4):591-8. PMID:
16400026
Article Published Date
: Jan 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Diabetes: Cataract
,
Diabetes Mellitus: Type 1
,
Diabetes Mellitus: Type 2
,
Oxidative Stress
Pharmacological Actions
:
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vascular Endothelial Growth Factor A Inhibitor
[+]
Cannabidiol has a neuroprotective effect in endotoxin-induced uveitis.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Mol Vis. 2008;14:2190-203. Epub 2008 Dec 3. PMID:
19052649
Article Published Date
: Jan 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Brain: Microglial Activation
,
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
,
Uveitis
Pharmacological Actions
:
Enzyme Inhibitors
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cannabidiol has a neuroprotective property in newborn rodent hypoxic ischemic insult.
Sep 26, 2016
Click here to read the entire abstract
Pubmed Data
: CNS Neurol Disord Drug Targets. 2016 Sep 27. Epub 2016 Sep 27. PMID:
27686886
Article Published Date
: Sep 26, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Brain Ischemia
,
Infant Neurological Development
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cannabidiol has a pharmacological profile which is compatible with that of an atypical antipsychotic agent.
Dec 31, 1990
Click here to read the entire abstract
Pubmed Data
: Psychopharmacology (Berl). 1991 ;104(2):260-4. PMID:
1678894
Article Published Date
: Dec 31, 1990
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Psychotic Disorders
Pharmacological Actions
:
Antipsychotic Agents
[+]
Cannabidiol has suppressive effects on antigen-specific antibody production.
May 31, 2007
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2007 Jun ;7(6):773-80. Epub 2007 Feb 15. PMID:
17466911
Article Published Date
: May 31, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Pharmacological Actions
:
Interferon Gamma Reducer
,
Interleukin-2 Downregulation
,
Interleukin-4 downregulation
[+]
Cannabidiol impairs fear memory reconsolidation in female rats through dorsal hippocampus CB1 but not CB2 receptor interaction.
Aug 28, 2022
Click here to read the entire abstract
Pubmed Data
: Eur Neuropsychopharmacol. 2022 Aug 29 ;64:7-18. Epub 2022 Aug 29. PMID:
36049316
Article Published Date
: Aug 28, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Post-Traumatic Stress Disorders (PTSD)
,
Psychiatric Disorder: Conditioned Fear
[+]
Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice.
Dec 23, 2010
Click here to read the entire abstract
Pubmed Data
: Br J Pharmacol. 2010 Dec 23. Epub 2010 Dec 23. PMID:
21182490
Article Published Date
: Dec 23, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Fulminant Hepatic Failure
,
Hepatic Encephalopathy
,
Liver Failure: Acute
Pharmacological Actions
:
Hepatoprotective
,
Neuroprotective Agents
[+]
Cannabidiol improves haloperidol-induced motor dysfunction in zebrafish.
Mar 03, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cannabis Res. 2023 Mar 4 ;5(1):6. Epub 2023 Mar 4. PMID:
36871008
Article Published Date
: Mar 03, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cannabidiol improves metabolic dysfunction in middle-aged diabetic rats submitted to a chronic cerebral hypoperfusion.
Sep 05, 2019
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2019 Sep 6:108819. Epub 2019 Sep 6. PMID:
31499052
Article Published Date
: Sep 05, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Cerebral Ischemia
,
Diabetic Complications
Pharmacological Actions
:
Anticholesteremic Agents
,
Hypolipidemic
,
Neuroprotective Agents
[+]
Cannabidiol improves muscular lipid profile by affecting the expression of fatty acid transporters and inhibiting de novo lipogenesis.
Mar 05, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2023 Mar 6 ;13(1):3694. Epub 2023 Mar 6. PMID:
36879113
Article Published Date
: Mar 05, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Diabetes Mellitus: Type 2
,
Obesity
Pharmacological Actions
:
Hypolipidemic
[+]
Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1.
Sep 04, 2019
Click here to read the entire abstract
Pubmed Data
: Redox Biol. 2019 Sep 5 ;28:101321. Epub 2019 Sep 5. PMID:
31518892
Article Published Date
: Sep 04, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Atopic Dermatitis
,
Skin Diseases: Inflammatory
Pharmacological Actions
:
Antioxidants
[+]
Cannabidiol induces apoptosis and perturbs mitochondrial function in human and canine glioma cells.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2021 ;12:725136. Epub 2021 Aug 11. PMID:
34456736
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Cancers: Canine
Pharmacological Actions
:
Apoptotic
[+]
Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1.
Apr 01, 2012
Click here to read the entire abstract
Pubmed Data
: FASEB J. 2012 Apr ;26(4):1535-48. Epub 2011 Dec 23. PMID:
22198381
Article Published Date
: Apr 01, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Intracellular adhesion molecule-1 (ICAM-1)
[+]
Cannabidiol inhibits symptoms of multiple sclerosis-like disease in mice.
Mar 30, 2011
Click here to read the entire abstract
Pubmed Data
: Br J Pharmacol. 2011 Mar 30. Epub 2011 Mar 30. PMID:
21449980
Article Published Date
: Mar 30, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Brain: Microglial Activation
,
Multiple Sclerosis
Pharmacological Actions
:
Immunomodulatory
,
Immunomodulatory: T-Cell down-regulation
[+]
Cannabidiol is a potential candidate for Parkinson's disease therapy.
Jan 20, 2022
Click here to read the entire abstract
Pubmed Data
: Neuroscience. 2022 08 21 ;498:64-72. Epub 2022 Jul 2. PMID:
35792194
Article Published Date
: Jan 20, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Neurodegenerative Diseases
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cannabidiol is a potential therapeutic for the affective-motivational dimension of incision pain in rats.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2017 ;8:391. Epub 2017 Jun 21. PMID:
28680401
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Allodynia
Pharmacological Actions
:
Analgesics
Additional Keywords
:
Dose Response
[+]
Cannabidiol is able to attenuate motor and cognitive impairments induced by reserpine.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2016 ;7:343. Epub 2016 Aug 28. PMID:
27733830
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Memory Disorders: Drug-Induced
,
Parkinson's Disease
,
Tardive Dyskinesia
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis.
Aug 14, 2000
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Proc Natl Acad Sci U S A. 2000 Aug 15 ;97(17):9561-6. PMID:
10920191
Article Published Date
: Aug 14, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Arthritis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Immunosuppressive Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cannabidiol may be a safe and useful therapeutic agent for treating Osteoarthritis joint neuropathic pain.
Aug 31, 2017
Click here to read the entire abstract
Pubmed Data
: Pain. 2017 Sep 1. Epub 2017 Sep 1. PMID:
28885454
Article Published Date
: Aug 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
Prophylactic Agents
Additional Keywords
:
Risk Reduction
[+]
Cannabidiol may be clinically useful in attenuating the rewarding effects of opioids.
Feb 28, 2013
Click here to read the entire abstract
Pubmed Data
: Addict Biol. 2013 Mar ;18(2):286-96. Epub 2012 Aug 2. PMID:
22862835
Article Published Date
: Feb 28, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Morphine Tolerance/Dependence
Problem Substances
:
Analgesic: Non-opioid
[+]
Cannabidiol may have potential as a preventative treatment for Alzheimer's disease.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2014 ;42(4):1383-96. PMID:
25024347
Article Published Date
: Dec 31, 2013
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Cannabidiol may represent a good candidate to normalize motility in patients with inflammatory bowel disease.
Jun 30, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Pharmacol. 2008 Jul ;154(5):1001-8. Epub 2008 May 12. PMID:
18469842
Article Published Date
: Jun 30, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Inflammatory Bowel Diseases
Pharmacological Actions
:
Enzyme Inhibitors
Problem Substances
:
Croton oil
[+]
Cannabidiol may represent a promising new protective strategy against cisplatin-induced nephrotoxicity.
Feb 28, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pharmacol Exp Ther. 2009 Mar ;328(3):708-14. Epub 2008 Dec 12. PMID:
19074681
Article Published Date
: Feb 28, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Chemoprotective Agents
[+]
Cannabidiol might be of therapeutic value in sleep disorders such as excessive somnolence.
Aug 06, 2006
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: FEBS Lett. 2006 Aug 7 ;580(18):4337-45. Epub 2006 Jul 10. PMID:
16844117
Article Published Date
: Aug 06, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Sleep Disorders
[+]
Cannabidiol might become a useful therapeutic tool for the attenuation and treatment of inflammatory lung diseases.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Immunopharmacol Immunotoxicol. 2015 Feb ;37(1):35-41. Epub 2014 Oct 30. PMID:
25356537
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Interstitial Lung Diseases
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cannabidiol modulates chronic neuropathic pain aversion behavior.
Aug 23, 2023
Click here to read the entire abstract
Pubmed Data
: Behav Brain Res. 2023 Aug 24 ;452:114588. Epub 2023 Jul 18. PMID:
37474023
Article Published Date
: Aug 23, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Neuropathic Pain
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
[+]
Cannabidiol modulates fear memory formation through Interactions with serotonergic transmission.
Jun 13, 2016
Click here to read the entire abstract
Pubmed Data
: Neuropsychopharmacology. 2016 Jun 14. Epub 2016 Jun 14. PMID:
27296152
Article Published Date
: Jun 13, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Psychiatric Disorder: Conditioned Fear
,
Traumatic Memory Formation
[+]
Cannabidiol modulates serotonergic transmission and prevents allodynia and anxiety-like behavior in a model of neuropathic pain.
Aug 26, 2018
Click here to read the entire abstract
Pubmed Data
: Pain. 2018 Aug 27. Epub 2018 Aug 27. PMID:
30157131
Article Published Date
: Aug 26, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Allodynia
,
Neuropathic Pain
Pharmacological Actions
:
Analgesics
,
Anti-Anxiety Agents
1
2
3
4
next ›
last »
