DHEA (Dehydroepiandrosterone)

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48 Diseases Researched for DHEA (Dehydroepiandrosterone)
NameACCKFocus
Adrenal Insufficiency 440Locked
Lupus Erythematosus: Systemic440Locked
Systemic Lupus Erythematosus440Locked
Addison's Disease330Locked
Hypoadrenalism330Locked
Postmenopausal Disorders220Locked
Aging211Locked
Infertility: Female211Locked
Osteoporosis211Locked
Advanced Glycation End products (AGE)110Locked
Aging Skin110Locked
Atrichia pubis110Locked
Bone Fractures110Locked
Cancers: All110Locked
Depression110Locked
Diabetes Mellitus: Type 2110Locked
Elderly: Age Specific Diseases110Locked
Giant Cell Arteritis110Locked
Heroin Addiction/Withdrawal110Locked
Hot Flash110Locked
Hypoactive Sexual Desire Disorder110Locked
Metabolic Diseases110Locked
Polymyalgia Rheumatica110Locked
Schizophrenia110Locked
Sjogren's Syndrome110Locked
Substance Use Disorders110Locked
Hypoxia36Locked
Breast Cancer34Locked
Hypertension: Pulmonary24Locked
Excitotoxicity 23Locked
Mercury Poisoning23Locked
Arteriosclerosis12Locked
Diabetes Mellitus: Type 112Locked
Pulmonary Hypertension12Locked
Vaccine-induced Toxicity 12Locked
Adrenopause11Locked
Autism Spectrum Disorders11Locked
Common Cold11Locked
Dysmenorrhea11Locked
Inflammation11Locked
Influenza11Locked
Liver Cancer11Locked
Low DHEA11Locked
Osteoarthritis11Locked
Progesterone: Low11Locked
Crohn's Disease10Locked
Encephalitis: Japanese10Locked
Ulcerative Colitis10Locked
10 Pharmacological Actions Researched for DHEA (Dehydroepiandrosterone)
NameACCKFocus
Hypoglycemic Agents212Locked
Neuroprotective Agents212Locked
Antidepressive Agents110Locked
Dermatologic Agents110Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor110Locked
Chemopreventive23Locked
Vasodilator Agents12Locked
Antineoplastic Agents11Locked
Antiviral Agents11Locked
Osteoprotective 11Locked

View the Evidence:
43 Abstracts with DHEA (Dehydroepiandrosterone) Research

[+]

Dehydroepiandrosterone supplementation results in stabilization of BMI, waist circumference and fasting glycaemia values in schizophrenic patients treated with olanzapine.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Psychiatr Pol. 2015;49(2):363-376. PMID: 26093599
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Metabolic Diseases
Pharmacological Actions : Hypoglycemic Agents
[+]

DHEA administration counteracts oxidative imbalance and advanced glycation end product formation in type 2 diabetic patients. Mar 01, 2009

Pubmed Data : Phytother Res. 2009 Mar;23(3):303-7. PMID: 17704347
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Advanced Glycation End products (AGE), Diabetes Mellitus: Type 2
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

DHEA administration during rehabilitation may restore WM integrity in the corpus callosum among polysubstance use disorder individuals.Aug 31, 2023

Pubmed Data : J Addict Med. 2023 Sep-Oct 01;17(5):551-556. Epub 2023 May 11. PMID: 37788608
Article Published Date : Aug 31, 2023
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Substance Use Disorders
Pharmacological Actions : Neuroprotective Agents
[+]

DHEA administration in women with adrenal fatigue normalizes the circulating levels of androgens. Apr 01, 2005

Pubmed Data : Arch Pharm Res. 2005 Apr;28(4):469-75. PMID: 15049961
Article Published Date : Apr 01, 2005
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Addison's Disease, Adrenal Insufficiency , Hypoadrenalism
[+]

DHEA has a therapeutic effect on pubic hair growth and psychological well-being in adolescents.Apr 01, 2009

Pubmed Data : J Clin Endocrinol Metab. 2009 Apr;94(4):1182-90. Epub 2009 Jan 6. PMID: 19126625
Article Published Date : Apr 01, 2009
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Adrenal Insufficiency , Atrichia pubis
[+]

DHEA improves symptoms of systemic lupus erythematosus. Dec 01, 1998

Pubmed Data : J Rheumatol. 1998 Dec;25(12):2352-6. PMID: 9858429
Article Published Date : Dec 01, 1998
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Lupus Erythematosus: Systemic, Systemic Lupus Erythematosus
[+]

DHEA is well tolerated and can reduce hot flashes. Jan 01, 2006

Pubmed Data : Support Cancer Ther. 2006 Jan 1;3(2):91-7. PMID: 18632445
Article Published Date : Jan 01, 2006
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Hot Flash
[+]

DHEA is well-tolerated and significantly reduces the number of SLE flares in women with mild-to-moderate systemic lupus erythematosus. Nov 01, 2002

Pubmed Data : Arthritis Rheum. 2002 Nov;46(11):2924-7. PMID: 12428233
Article Published Date : Nov 01, 2002
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Lupus Erythematosus: Systemic, Systemic Lupus Erythematosus
[+]

DHEA may be effective as a treatment for women with hypoactive sexual desire disorder.Jul 31, 2013

Pubmed Data : Eur Neuropsychopharmacol. 2013 Aug ;23(8):910-8. Epub 2012 Oct 18. PMID: 23084789
Article Published Date : Jul 31, 2013
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Hypoactive Sexual Desire Disorder
[+]

DHEA may be helpful in female patients with hypoadrenalism, mainly in restoring androgen levels. Sep 01, 2004

Pubmed Data : J Endocrinol Invest. 2004 Sep;27(8):736-41. PMID: 15636426
Article Published Date : Sep 01, 2004
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Addison's Disease, Adrenal Insufficiency , Hypoadrenalism
[+]

DHEA replacement is well-tolerated and effective in improving steroid deficiency and psychological function in patients with Addison's disease. Oct 01, 1995

Pubmed Data : Bioorg Med Chem. 1995 Oct;3(10):1345-8. PMID: 11134123
Article Published Date : Oct 01, 1995
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Addison's Disease, Adrenal Insufficiency , Hypoadrenalism
[+]

DHEA restores concentrations of sex steroids in primary Sjogren's syndrome. Jun 01, 2009

Pubmed Data : J Clin Endocrinol Metab. 2009 Jun;94(6):2044-51. Epub 2009 Mar 24. PMID: 19318446
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Sjogren's Syndrome
[+]

DHEA significantly reduces serum levels of proinflammatory cytokines in women witih systemic lupus erythematosus. Dec 01, 2004

Pubmed Data : Ann Rheum Dis. 2004 Dec;63(12):1623-6. PMID: 15547086
Article Published Date : Dec 01, 2004
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Lupus Erythematosus: Systemic, Systemic Lupus Erythematosus
[+]

DHEA supplementation augments ovarian stimulation in poor responders. Apr 01, 1998

Pubmed Data : Carcinogenesis. 1998 Apr;19(4):611-6. PMID: 11006185
Article Published Date : Apr 01, 1998
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Infertility: Female
[+]

DHEA supplementation improved lower extremity strength and function in older, frail women involved in a gentle exercise program of chair aerobics or yoga.Oct 25, 2008

Pubmed Data : Pharmacol Biochem Behav. 2008 Oct 25. [Epub ahead of print] PMID: 20863330
Article Published Date : Oct 25, 2008
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Elderly: Age Specific Diseases, Osteoporosis
Additional Keywords : Sex Hormone-Binding Globulin
[+]

DHEA supplementation improves symptoms in patients with system lupus erythematosus. Sep 01, 1994

Pubmed Data : Arthritis Rheum. 1994 Sep;37(9):1305-10. PMID: 7945493
Article Published Date : Sep 01, 1994
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Lupus Erythematosus: Systemic, Systemic Lupus Erythematosus
[+]

DHEA supplementation may improve the negative, depressive and anxiety symptoms of patients with schizophrenia. Feb 01, 2003

Pubmed Data : 1: Arch Gen Psychiatry. 2003 Feb;60(2):133-41. PMID:12578430
Article Published Date : Feb 01, 2003
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Schizophrenia
[+]

DHEA supplementation results in an improvement of symptoms in women experiencing early and late postmenopause.Nov 01, 2004

Pubmed Data : Epidemiology. 2004 Nov;15(6):653-9. PMID: 11109974
Article Published Date : Nov 01, 2004
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Postmenopausal Disorders
Additional Keywords : Sex Hormone-Binding Globulin
[+]

DHEA treatment may be therapeutic in treating heroin addiction. Jun 01, 2008

Pubmed Data : Eur Neuropsychopharmacol. 2008 Jun;18(6):406-13. Epub 2008 Mar 17. PMID: 18346881
Article Published Date : Jun 01, 2008
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Heroin Addiction/Withdrawal
[+]

DHEA, in appropriate dosages, may have significant anti-aging and anti-cancer activity. Jan 01, 2005

Pubmed Data : Acupunct Electrother Res. 2005;30(3-4):219-61. PMID: 16617690
Article Published Date : Jan 01, 2005
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Aging, Cancers: All
[+]

Due to the relatively low levels of DHEA found in patients with untreated polymyalgia rheumatica/giant cell arteritis, it may have therapeutic value in their treatment. Dec 01, 2010

Pubmed Data : J Endocrinol. 2010 Dec;207(3):319-28. Epub 2010 Sep 24. PMID: 16783861
Article Published Date : Dec 01, 2010
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Giant Cell Arteritis, Polymyalgia Rheumatica
[+]

Higher testosterone levels in both genders and higher DHEA-S levels in women predicted a more than 60% lower risk of falling. Sep 01, 2008

Pubmed Data : Osteoporos Int. 2008 Sep;19(9):1307-14. Epub 2008 Mar 20. PMID: 18351428
Article Published Date : Sep 01, 2008
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone), Testosterone
Diseases : Bone Fractures
[+]

Oral dehydroepiandrosterone restores ß-endorphin response to OGTT in early and late postmenopause.Aug 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Gynecol Endocrinol. 2019 Sep ;35(9):767-771. Epub 2019 Apr 2. PMID: 30935252
Article Published Date : Aug 31, 2019
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Postmenopausal Disorders
[+]

Plasma levels of androsterone may contribute to the antidepressant effects of DHEA.Jun 24, 2015

Pubmed Data : Psychopharmacology (Berl). 2015 Jun 25. Epub 2015 Jun 25. PMID: 26105109
Article Published Date : Jun 24, 2015
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

These data suggest the possibility that topical DHEA could be used as an efficient and physiological antiageing skin agent.Oct 31, 2010

Pubmed Data : Br J Dermatol. 2010 Nov ;163(5):968-76. PMID: 20698844
Article Published Date : Oct 31, 2010
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Aging Skin
Pharmacological Actions : Dermatologic Agents
[+]

Dehydroepiandrosterone (DHEA) prevents and reverses chronic hypoxic pulmonary hypertension.Aug 05, 2003

Pubmed Data : Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9488-93. Epub 2003 Jul 23. PMID: 12878719
Article Published Date : Aug 05, 2003
Study Type : Animal Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Hypertension: Pulmonary, Hypoxia
[+]

Dehydroepiandrosterone sulphate reduces chronic hypoxic pulmonary hypertension in rats.Mar 01, 1997

Pubmed Data : Biol Pharm Bull. 1997 Mar;20(3):243-8. PMID: 12765434
Article Published Date : Mar 01, 1997
Study Type : Animal Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Hypoxia, Pulmonary Hypertension
[+]

Dehydroepiandrosterone upregulates inhibits hypoxic pulmonary hypertension.Jun 01, 2007

Pubmed Data : Cardiovasc Res. 2007 Jun 1;74(3):377-87. Epub 2007 Feb 12. PMID: 17346686
Article Published Date : Jun 01, 2007
Study Type : Animal Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Hypertension: Pulmonary, Hypoxia
Pharmacological Actions : Vasodilator Agents
[+]

DHEA attenuates the cardiac impairment induced by a high-fat diet in rabbits. Jul 03, 2009

Pubmed Data : Life Sci. 2009 Jul 3;85(1-2):77-84. Epub 2009 May 7. PMID: 19427326
Article Published Date : Jul 03, 2009
Study Type : Animal Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Arteriosclerosis
[+]

DHEA intake protects against chemically-induced mammary tumor development in obese rats. Aug 01, 2010

Pubmed Data : Oncol Rep. 2010 Aug;24(2):357-62. PMID: 20596621
Article Published Date : Aug 01, 2010
Study Type : Animal Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Breast Cancer
Pharmacological Actions : Chemopreventive
[+]

Diosgenin-induced increase in the DHEA level may contribute to the improvement of hyperglycemia.Aug 31, 2014

Pubmed Data : J Steroid Biochem Mol Biol. 2014 Sep ;143:152-9. Epub 2014 Mar 7. PMID: 24607838
Article Published Date : Aug 31, 2014
Study Type : Animal Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Hypoglycemic Agents
[+]

Neonatal exposure to thimerosal-containing vaccines might induce excitotoxic brain injuries, leading to neurodevelopmental disorders. DHEA may protect against mercury-induced neurotoxicity. Oct 21, 2011

Pubmed Data : Neurochem Res. 2011 Oct 21. Epub 2011 Oct 21. PMID: 22015977
Article Published Date : Oct 21, 2011
Study Type : Animal Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Excitotoxicity , Mercury Poisoning, Vaccine-induced Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Mercury, Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

Autism spectrum disorders are associated with immunoexcitotoxicity. Jan 01, 2009

Pubmed Data : Altern Ther Health Med. 2009 Jan-Feb;15(1):60-7. PMID: 19161050
Article Published Date : Jan 01, 2009
Study Type : Commentary
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Autism Spectrum Disorders, Excitotoxicity , Inflammation, Mercury Poisoning
Additional Keywords : Diseases that are Linked
[+]

Colds and influenza: a review of diagnosis and conventional, botanical, and nutritional considerations.Feb 28, 2007

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Altern Med Rev. 2007 Mar ;12(1):25-48. PMID: 17397266
Article Published Date : Feb 28, 2007
Study Type : Review
Additional Links
Substances : Astragalus, DHEA (Dehydroepiandrosterone), Elderberry, NAC (N-acetyl-L-cysteine), Olive leaf extract, Onion, Vitamin A, Vitamin C
Diseases : Common Cold, Influenza
Pharmacological Actions : Antiviral Agents
Additional Keywords : Phytotherapy
[+]

Dehydroepiandrosterone (DHEA) inhibits liver cancer cell growth.Nov 01, 2008

Pubmed Data : Int J Oncol. 2008 Nov;33(5):969-77. PMID: 18949359
Article Published Date : Nov 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Liver Cancer
[+]

Dehydroepiandrosterone (DHEA) significantly reduces the growth of estrogen and progesterone-receptor-negative breast cancers.May 01, 2007

Pubmed Data : World J Surg. 2007 May;31(5):1041-6. PMID: 17429562
Article Published Date : May 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Breast Cancer
[+]

Dehydroepiandrosterone and experimental osteoarthritis.Dec 31, 2017

Pubmed Data : Vitam Horm. 2018 ;108:367-384. Epub 2018 Feb 19. PMID: 30029735
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

DHEA levels decline with age and low levels are associated with a variety of adverse health consequences.Jul 01, 2008

Pubmed Data : Pol Merkur Lekarski. 2008 Jul;25(145):77-82. PMID: 18839621
Article Published Date : Jul 01, 2008
Study Type : Review
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Adrenopause, Aging, Low DHEA
[+]

Review on natural supplements for treating osteoporosis.May 01, 2006

Pubmed Data : Ann Pharmacother. 2006 May;40(5):836-49. Epub 2006 May 2. PMID: 16670364
Article Published Date : May 01, 2006
Study Type : Review
Additional Links
Substances : DHEA (Dehydroepiandrosterone), phytoestrogens, Vitamin K
Diseases : Osteoporosis
Additional Keywords : Vitamin K2
[+]

These data suggest that cinnamaldehyde selectively induced progesterone production and inhibited production of testosterone and dehydroepiandrosterone in human adrenal cells, which may confirm its traditional use for menstrual pain and infertility. Jun 05, 2010

Pubmed Data : Life Sci. 2010 Jun 5;86(23-24):894-8. Epub 2010 Apr 25. PMID: 20423713
Article Published Date : Jun 05, 2010
Study Type : In Vitro Study
Additional Links
Substances : Cinnamaldehyde, DHEA (Dehydroepiandrosterone), Progesterone
Diseases : Dysmenorrhea, Infertility: Female, Progesterone: Low
Additional Keywords : Science Confirms Tradition
[+]

Various plant substances inhibit chemically-induced mammary gland tumor promotion. Mar 01, 2008

Pubmed Data : Nutr Cancer. 2008 Mar-Apr;60(2):227-34. PMID: 1905902
Article Published Date : Mar 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Beta Sitosterol, Curcumin, D-Limonene, DHEA (Dehydroepiandrosterone), Silymarin
Diseases : Breast Cancer
Pharmacological Actions : Antineoplastic Agents, Chemopreventive
[+]

Dehydroepiandrosterone (DHEA) was demonstrated to be safe and effective in patients with refractory Crohn's disease or ulcerative colitis.Feb 01, 2003

Pubmed Data : Aliment Pharmacol Ther. 2003 Feb;17(3):409-14. PMID: 12562454
Article Published Date : Feb 01, 2003
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Crohn's Disease, Ulcerative Colitis
[+]

DHEA has antiviral effects against Japanese encephalitis virus infection.Sep 01, 2005

Pubmed Data : J Gen Virol. 2005 Sep;86(Pt 9):2513-23. PMID: 16099910
Article Published Date : Sep 01, 2005
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Encephalitis: Japanese

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