EGCG (Epigallocatechin gallate)

Name	AC	CK
Obesity	32	121
Oxidative Stress	33	70
Breast Cancer	29	61
Cancers: All	39	59
Inflammation	32	55
Multiple Sclerosis	8	53
Alzheimer's Disease	29	37
Lung Cancer	28	37
Down Syndrome	8	34
Hypertension	5	32
Diabetes Mellitus: Type 2	13	30
Head and Neck Cancer	9	30
Inflammatory Bowel Diseases	7	28
Coronavirus Infection	24	26
High Fat Diet	13	26
Prostate Cancer	16	26
Breast Cancer: Triple Negative	6	25
Atherosclerosis	8	22
High Cholesterol	1	20
Liver Cancer	17	20
Neurodegenerative Diseases	16	20
Parkinson's Disease	15	20
Aging	6	19
Cancers: Drug Resistant	15	17
Metabolic Syndrome X	6	17
Wound Healing	5	16
Hyperlipidemia	4	15
Melanoma	11	15
Nonalcoholic fatty liver disease (NAFLD)	8	15
Pancreatic Cancer	12	15
Stroke: Attenuation/Recovery	4	15
Vitiligo	2	15
Esophageal Cancer	5	14
Lipid Peroxidation	3	14
Lipopolysaccharide-Induced Toxicity	10	14
Radiation	3	14
Arsenic Poisoning	7	13
Periodontal Diseases	3	13
Pre-Eclampsia	3	13
Brain Inflammation	9	12
Brain Ischemia	2	12
Cervical Cancer	13	12
Chemotherapy and Radiation Toxicity	2	12
Colorectal Cancer	7	12
Coronavirus Disease (Covid-19)	3	12
Diabetic Complications	8	12
Hepatitis C	3	12
Breast Cancer: Metastatic	2	11
MRSA	2	11
Ovarian Cancer	11	11
Scars	2	11
Staphylococcus aureus: Methicillin-resistant (MRSA)	2	11
Acne	1	10
Anogenital Warts	1	10
Bisphenol Toxicity	6	10
Cardiovascular Disease: Prevention	1	10
Cholesterol: High	1	10
Cystic Fibrosis	1	10
Dental Caries: Children	1	10
Dermatitis	1	10
Elderly: Age Specific Diseases	1	10
Genital Warts	1	10
Herpes Simplex Virus Type 1	1	10
Human Papillomavirus (HPV)	8	10
Insulin Resistance	5	10
Multiple Sclerosis: Relapsing-Remitting	1	10
Myocardial Ischemia	7	10
Overweight	1	10
Pneumonia	1	10
Prostate: PSA Doubling	1	10
Radiation Induced Illness: Mucositis	1	10
Radiotherapy	1	10
Rheumatoid Arthritis	7	10
Triglycerides: Elevated	1	10
Ulcerative Colitis	1	10
Cardiac Hypertrophy	5	9
Chemically-Induced Liver Damage	5	9
Colon Cancer	7	9
Endometriosis	7	9
Multiple Myeloma	6	9
Air Pollution Linked Toxicity	3	8
Bladder Cancer	6	8
Chemotherapy-Induced Toxicity: Doxorubicin	6	8
Diabetic Nephropathy	5	8
Kidney Damage	4	8
Myocardial Fibrosis	4	8
Periodontitis	5	8
Autoimmune Diseases	5	7
Cardiovascular Diseases	6	7
Escherichia coli Infections	7	7
Influenza A	6	7
Osteoporosis	4	7
Pseudomonas aeruginosa	6	7
Sjogren's Syndrome	5	7
Steptococcus Mutans Infections	7	7
Advanced Glycation End products (AGE)	4	6
Asthma	3	6
Cancer Metastasis	4	6
Chemotherapy-Induced Toxicity: Cisplatin	3	6
Diabetes Mellitus: Type 1	4	6
HIV Infections	6	6
Hyperglycemia	3	6
Hyperuricemia	3	6
Muscle Atrophy	3	6
Myocardial Infarction	3	6
Smoking	4	6
Alopecia	1	5
Amyotrophic Lateral Sclerosis	3	5
Brain: Oxidative Stress	4	5
Cadmium Poisoning	3	5
Cancers: Multi-Drug Resistant	5	5
Carcinoma: Non-Small-Cell Lung	4	5
Cataract	4	5
Chlamydia pneumoniae	1	5
Colitis	3	5
Coronary Artery Disease	3	5
Dysbiosis	3	5
Endotoxemia	3	5
Gastric Cancer	4	5
Glioblastoma	5	5
Hair Loss	1	5
Heart Failure	3	5
Kidney Damage: Chemically-Induced	3	5
Leiomyoma	3	5
Neuroblastoma	3	5
Oral Cancer	5	5
Prostatic Hyperplasia: Benign	3	5
Acetaminophen (Tylenol) Toxicity	2	4
Alcoholic Liver Disease	2	4
Anxiety	2	4
Chemotherapy-Induced Toxicity: Cyclophosphamide	2	4
Endometrial Cancer	4	4
Erectile Dysfunction	2	4
Hepatitis B	4	4
High Sugar Diet	3	4
Kidney Diseases	2	4
Liver Damage	2	4
Liver Damage: Drug-Induced	2	4
Liver Fibrosis	3	4
Lung Injury: Acute	2	4
Middle Cerebral Artery Occlusion (MCAO)	2	4
Nicotine/Tobacco Toxicity	2	4
Porphyromonas gingivalis	2	4
Salmonella Infections	3	4
Squamous cell carcinoma	3	4
Staphylococcus aureus infection	4	4
Acinetobacter baumannii infection	3	3
Acrylamide-induced toxicity	2	3
Anthrax	2	3
Atrial Fibrillation	2	3
Burns	2	3
Cachexia: Cancer	2	3
Cancer Stem Cells	3	3
Carcinoma: Small Cell Lung	2	3
Chemotherapy-Induced Toxicity: Gentamicin	2	3
Chronic Lymphocytic Leukemia	2	3
Clostridium Infections	2	3
Depression	2	3
Dry Eye Syndromes	2	3
Fatty Liver	2	3
Fibrosis	2	3
Fluoride Toxicity	2	3
High Fructose Diet	2	3
Hypoglycemia	2	3
Hypoxia	3	3
Infertility: Female	1	3
Iron Overload	2	3
Kidney Cancer	3	3
Kidney Fibrosis	3	3
Liver Cancer: Prevention	2	3
Lymphoma	2	3
Metabolic Diseases	2	3
Nasopharyngeal Cancer	2	3
Neuropathic Pain	2	3
Osteoarthritis	3	3
Osteosarcoma	3	3
Pulmonary Fibrosis	2	3
Skin Cancer	3	3
Stroke: Ischemic	2	3
Thyroid Cancer	2	3
Aging Skin	1	2
Alcohol Toxicity	1	2
Aluminum Toxicity	1	2
Aneurysm: Aortic	1	2
Arthritis	1	2
Arthritis: Rheumatoid	2	2
Asbestos Toxicity	2	2
Asthma: Bronchial	1	2
Autoimmune Thyroiditis	1	2
Benzo[a]pyrene-induced Toxicity	1	2
Bone Cancer	1	2
Brain Cancer	2	2
Brain Injury: Hippocampal Damage	1	2
C-Reactive Protein	1	2
Cancers	2	2
Cardiac Mortality	1	2
Cardiomyopathy: Restrictive	1	2
Cerebral Hypoperfusion	1	2
Cerebral Ischemia	1	2
Chemotherapy	1	2
Chemotherapy-Induced Kidney Damage	1	2
Chemotherapy-Induced Toxicity: Bleomycin	1	2
Chemotherapy-Induced Toxicity: Irinotecan	1	2
Chikungunya Virus	2	2
Cholangiocarcinoma	2	2
Cholecystitis	1	2
Chronic Fatigue Syndrome	1	2
Chronic Pain	1	2
Cognitive Decline/Dysfunction	1	2
Coronary Bypass Surgery	1	2
DNA damage	1	2
Dental Caries	2	2
Diabetes Mellitus: Type 1: Prevention	1	2
Diabetes: Cardiovascular Illness	1	2
Diabetes: Cataract	1	2
Diabetes: Oxidative Stress	1	2
Diabetic Retinopathy	2	2
Drug Toxicity: Methotrexate	1	2
Encephalomyelitis	2	2
Endothelial Dysfunction	2	2
Epilepsy	1	2
Fetal Origin of Adult Disease	1	2
Fibroid Tumor	1	2
Fibroids: Uterine	1	2
Fish Diseases	1	2
Gallbladder Inflammation	1	2
Gallstones	1	2
Gastrointestinal Inflammation	1	2
Gastrointestinal Stromal Tumors	1	2
Gestational Diabetes	1	2
Gingivitis	1	2
Glaucoma	1	2
Glioma	2	2
Glomerulonephritis	1	2
Gout	1	2
Graft vs Host Disease	1	2
H1N1 Infection	2	2
Halitosis	2	2
Herpes Simplex Virus Type 2	2	2
Huntington Disease	1	2
Hydrogen Peroxide Induced Toxicity	2	2
Infection: Antibiotic Resistant	2	2
Inflammation: Neutrophil-Mediated	1	2
Influenza	2	2
Influenza B	2	2
Ischemia	1	2
Learning disorders	1	2
Leiomyosarcoma	2	2
Leukemia: Acute promyelocytic leukemia	2	2
Leukemia: Chronic Lymphocytic Leukemia (CLL)	2	2
Leukemia: T-cell acute Lymphoblastic	2	2
Lung Damage	1	2
Lung Infection	1	2
Melanoma: Metastatic	1	2
Memory Loss	1	2
Microplastic Toxicity	1	2
Mitochondrial Dysfunction	2	2
Mobile Phone-Induced Oxidative Stress	1	2
Morphine Tolerance/Dependence	1	2
Muscular Dystrophies	1	2
Neural Tube Defects	1	2
Non-Hodgkin's lymphoma: B Cell	2	2
Obstructive Nephropathy	1	2
Pancreatitis	1	2
Peripheral Nerve Diseases	1	2
Puberty: Precocious	1	2
Respiratory Diseases	2	2
Retinal Diseases	1	2
Rhabdomyosarcoma	2	2
Sciatica	1	2
Sepsis	1	2
Silicosis	1	2
Skin Diseases: Photo-Aging	1	2
Tardive Dyskinesia	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Thyroiditis: Autoimmune	1	2
Tongue Cancer	1	2
Uveitis	1	2
Venous Thrombosis	1	2
Williams Syndrome	1	2
Wound Healing: Delayed	1	2
Xeroderma Pigmentosum	1	2
Acanthamoeba infection	1	1
Acid Reflux	1	1
Aflatoxicosis	1	1
Aging: Brain	1	1
Allergies	1	1
Amyloidosis	1	1
Animal Diseases: Porcine Circovirus Type 2 (PCV2)	1	1
Avian Influenza	1	1
Bacterial Infections	1	1
Bacterial Infections and Mycoses	1	1
Barrett Esophagus	1	1
Bile Duct Cancer	1	1
Breast Cancer Stem Cells	1	1
Burkitt Cell Leukemia	1	1
Candida Infection	1	1
Cerebral Stroke	1	1
Cholesterol: Oxidation	1	1
Choriocarcinoma	1	1
Chronic Myeloid Leukemia	1	1
Degenerative Disk Disease	1	1
Dengue	1	1
Dengue Fever	1	1
Diabetes: Liver Disease	1	1
Drug-Induced Toxicity: Gastrointestinal	1	1
Drug-Induced Toxicity: Indomethacin	1	1
Ebola Virus Infections	1	1
Encephalitis: Japanese	1	1
Enterovirus	1	1
Epstein-Barr Virus Infections	1	1
Eye Diseases	1	1
Fibrosis: Liver	1	1
Follicular Lymphoma	1	1
Food Allergies	1	1
Foodborne Pathogens: Prevention/Food Preservation	1	1
Fungal Infections: Biofilm Formation/Resistance	1	1
Gastrointestinal Diseases	1	1
H3N2 Infection	1	1
HSV-1	1	1
HSV-2	1	1
Hearing Loss	1	1
Helicobacter Pylori Infection	1	1
Human T-Cell Lymphotrophic Virus type 1 associated disease	1	1
Intestinal Permeability	1	1
Keloid	1	1
Klebsiella Infections	1	1
Leaky Gut Syndrome	1	1
Leukemia: Acute myelogenous leukemia (AML)	1	1
Leukemia: Chronic myelogenous leukemia (CML)	1	1
Liver Cancer: Metastatic	1	1
Liver Diseases	1	1
Lung Injury: Smoke-Induced	1	1
Mastocytoma	1	1
Medulloblastoma	1	1
Mesothelioma	1	1
Mitochondrial Diseases	1	1
Multiple System Atrophy (MSA)	1	1
Nasopharyngeal Cancer Stem Cells	1	1
Neurologic Disorders	1	1
Non-Small-Cell Lung Carcinoma	1	1
Norovirus	1	1
Osteomyelitis	1	1
Pesticide Toxicity	1	1
Pituitary Diseases	1	1
Polio	1	1
Pregnancy Complications	1	1
Promyelocytic leukemia	1	1
Prostate Cancer: Prevention	1	1
Rabies	1	1
Retinitis Pigmentosa	1	1
Ricin Toxicity	1	1
Salivary Gland Adenoid Cystic Carcinoma.	1	1
Spinal Cord Injuries	1	1
Staphylococcus epidermidis	1	1
Stomach Cancer	1	1
Streptococcus Infections	1	1
Streptococcus pneumoniae infection	1	1
Subarachnoid hemorrhage	1	1
Swine Flu Associated Virus	1	1
T-Cell Mediated Diseases	1	1
Testicular Cancer	1	1
Thrombocytopenia	1	1
Viral Infections	1	1
West Nile Fever	1	1
Zika Virus	1	1

Name	AC	CK
Anti-Inflammatory Agents	125	229
Antioxidants	120	208
Antiproliferative	105	166
Apoptotic	99	145
Neuroprotective Agents	70	119
Hypolipidemic	17	72
Antiviral Agents	51	70
Chemopreventive	49	69
Cardioprotective	33	60
Gastrointestinal Agents	19	60
Interleukin-6 Downregulation	19	60
Anti-Apoptotic	35	54
Tumor Necrosis Factor (TNF) Alpha Inhibitor	29	53
Interleukin-1 beta downregulation	18	52
MicroRNA modulator	34	48
Radioprotective	8	47
Anti-metastatic	28	43
Anticholesteremic Agents	4	42
Antihypertensive Agents	5	41
Hepatoprotective	23	41
Immunomodulatory	27	40
Nrf2 activation	23	39
Anticarcinogenic Agents	23	38
Anti-Bacterial Agents	26	37
Chemosensitizer	25	35
NF-kappaB Inhibitor	25	35
Chemotherapeutic	27	31
Renoprotective	15	27
Hypoglycemic Agents	9	25
Anti-Fibrotic	15	23
Heme oxygenase-1 up-regulation	12	21
Chemoprotective Agents	13	20
Antimicrobial	8	19
Angiogenesis Inhibitors	12	18
Matrix metalloproteinase-2 (MMP-2) inhibitor	7	18
Antineoplastic Agents	12	15
Autophagy Up-regulation	6	15
Anti-Anxiety Agents	3	14
Anti-Angiogenic	9	13
Cell cycle arrest	12	13
Matrix metalloproteinase-9 (MMP-9) inhibitor	3	13
Vascular Endothelial Growth Factor Inhibitors	6	13
Interleukin-8 downregulation	7	12
Vascular Endothelial Growth Factor Regulator	3	12
Radiosensitizer	2	11
Tumor Suppressor Protein p53 Upregulation	8	11
Dermatologic Agents	1	10
Hepatocyte growth factor (HGF) inhibitor	1	10
Thermogenic	1	10
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	5	9
Cyclooxygenase 2 Inhibitors	6	7
Anti-Glycation Agents	4	6
Immunomodulatory: Th17 downregulation	3	6
Multidrug Resistance Gene Modulators	6	6
Osteoprotective	4	6
Quorum Sensing Inhibition	5	6
Bcl-2 protein down-regulation	4	5
Gastroprotective	3	5
Interleukin-18 down-regulation	3	5
Malondialdehyde Down-regulation	3	5
NF-E2-Related Factor-2 (Nrf2) Modulator	3	5
Neuritogenic	4	5
Wnt/β-catenin signaling pathway modulation	4	5
Anti-Adipogenic	3	4
Anti-HIV Agents	4	4
Autophagy Inhibitors	3	4
Cytoprotective	3	4
Hypoxia-inducible factor-1 (HIF-1) inhibitor	2	4
Interleukin-10 upregulation	2	4
Interleukin-17 downregulation	2	4
P21 Activation	2	4
Prophylactic Agents	3	4
Regenerative	3	4
Telomerase Inhibitor	4	4
Uricosuric Agents	2	4
Anti-Cachexic Agents	2	3
Anti-Proliferative	3	3
Antidepressive Agents	2	3
Brain-derived neurotrophic factor modulator	2	3
Enzyme Inhibitors	3	3
Epidermal growth factor receptor (EGFR) inhibitor	2	3
Fertility Agents: Female	1	3
Gluconeogenesis Inhibitor	2	3
Glutathione Upregulation	2	3
STAT3 Inhibitor	2	3
Wnt/β-catenin pathway down-regulation	2	3
Aldose reductase inhibitor	1	2
Analgesics	2	2
Anti-Asthmatic Agents	1	2
Antinoceceptive	1	2
Appetite Depressants	1	2
Calcium Desensitizer	1	2
Detoxifier	1	2
Genoprotective	1	2
Histone deacetylase inhibitor	2	2
Immunostimulatory	1	2
Insecticidal	1	2
Insulin Sensitizers	1	2
Interleukin-2 Downregulation	1	2
Interleukin-4 downregulation	1	2
Matrix Metalloproteinases Inhibitors	1	2
Neurogenesis	1	2
Neurorestorative	1	2
Pancreato Protective Agents	2	2
Reverse Transcriptase Inhibitors	2	2
Superoxide Dismutase Up-regulation	1	2
Telomere Protective	1	2
Transforming growth factor beta (TGF-β) inhibitor	2	2
Tumor Necrosis Factor (TNF) Alpha Enhancer	1	2
Vascular Endothelial Growth Factor A Inhibitor	1	2
Vasodilator Agents	1	2
Viral Hemagglutinin Inhibitor	2	2
Xanthine oxidase inhibitor	1	2
AMP-activated protein kinase modulation	1	1
Adiponectin upregulation	1	1
Alpha-amylase inhibitor	1	1
Alpha-glucosidase inhibitor	1	1
Angiotensin-Converting Enzyme Inhibitors	1	1
Anti-Allergic Agents	1	1
Antifungal Agents	1	1
Antiparasitic Agents	1	1
Cell Differentiation Inducer	1	1
Chemotherapeuticm	1	1
Cyclooxygenase 1 Inhibitor	1	1
Drug synergy	1	1
Interleukin-10 downregulation	1	1
Ionophores	1	1
Iron Chelating Agents	1	1
Lactate Dehydrogenase A Inhibitor	1	1
Neurominidase Inhibitor	1	1
P38 Mitogen-Activated Protein Kinase Modulator	1	1
Prostaglandin Antagonists	1	1
Proteasome Inhibitors	1	1
Proton Pump Inhibitor	1	1
STAT3-NFκB Signaling: downregulation	1	1

[+]

Consumption of green tea EGCG resulted in a significant reduction of low-density lipoprotein cholesterol.Jun 19, 2016

Click here to read the entire abstract

Pubmed Data : Int J Food Sci Nutr. 2016 Jun 20:1-8. Epub 2016 Jun 20. PMID: 27324590

Article Published Date : Jun 19, 2016

Study Type : Meta Analysis

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : High Cholesterol

Pharmacological Actions : Anticholesteremic Agents

[+]

Sulforaphane and EGCG restore estrogen receptor expression by modulating epigenetic events in the breast cancer cell line MDA-MB-231.Oct 17, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutrigenet Nutrigenomics. 2017 Oct 18 ;10(3-4):126-135. Epub 2017 Oct 18. PMID: 29040973

Article Published Date : Oct 17, 2017

Study Type : Meta Analysis, Review

Additional Links

Substances : EGCG (Epigallocatechin gallate), Sulforaphane

Diseases : Breast Cancer: Triple Negative

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Epigenetic Modification In Cancer

[+]

The effects of green tea on weight loss and weight maintenance.Aug 31, 2009

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2019 09 19 ;9(1):13593. Epub 2019 Sep 19. PMID: 31537880

Article Published Date : Jan 18, 2019

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Hepatitis C

Pharmacological Actions : Antiviral Agents

Additional Keywords : Natural Substance/Drug Synergy

[+]

Administration of polyphenon E resulted in a therapeutic benefit for patients who were refractory to 5-aminosalicylic and/or azathioprine.Jul 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Inflamm Bowel Dis. 2013 Aug ;19(9):1904-12. PMID: 23846486

Article Published Date : Jul 31, 2013

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Ulcerative Colitis

Pharmacological Actions : Gastrointestinal Agents

[+]

[+]

Decaffeinated green tea extract resulted in significant reductions in lesions located on the nose, perioral area and chin.Mar 31, 2016

Click here to read the entire abstract

Pubmed Data : Complement Ther Med. 2016 Apr ;25:159-63. Epub 2016 Mar 7. PMID: 27062963

Article Published Date : Mar 31, 2016

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Acne

Additional Keywords : Plant Extracts

[+]

Decreases in inflammatory levels in patients with multiple sclerosis after treatment with epigallocatechin gallate and coconut oil.Sep 15, 2021

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Pubmed Data : Nutrients. 2021 Sep 16 ;13(9). Epub 2021 Sep 16. PMID: 34579104

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2021 Nov 17 ;13(11). Epub 2021 Nov 17. PMID: 34836374

Article Published Date : Nov 16, 2021

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Hyperlipidemia

Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic

Additional Keywords : Plant Extracts

[+]

EGCG and coconut oil improve state anxiety and functional capacity in patients with multiple sclerosis.Jan 22, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Additional Keywords : Risk Reduction

[+]

Green tea catechins may have a therapeutic role in the treatment of metabolic syndrome. Jan 01, 2009

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Pubmed Data : Phytochemistry. 2009 Jan;70(1):11-24. Epub 2009 Jan 13. PMID: 19147161

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Metabolic Syndrome X

[+]

Green tea polyphenon E and erlotinib combination was well tolerated in patients with APLs of the head and neck.Jan 14, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Cancer Res. 2020 11 15 ;26(22):5860-5868. Epub 2020 Sep 17. PMID: 32943457

Article Published Date : Jan 14, 2020

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Head and Neck Cancer

Pharmacological Actions : Chemopreventive

[+]

High-dose green tea extract resulted in significant weight loss, reduced waist circumference, and a consistent decrease in total cholesterol and LDL plasma levels.May 28, 2015

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Pubmed Data : Clin Nutr. 2015 May 29. Epub 2015 May 29. PMID: 26093535

Pubmed Data : Am J Clin Nutr. 2016 Nov 2. Epub 2016 Aug 2. PMID: 27806972

Article Published Date : Nov 01, 2016

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Cardiovascular Disease: Prevention, Triglycerides: Elevated

Pharmacological Actions : Anticholesteremic Agents, Hypolipidemic

Additional Keywords : Natural Substance/Drug Antagonism, Plant Extracts

Problem Substances : Statin Drugs

[+]

Tea polyphenol has potential to be a therapeutic adjuvant against human metastatic breast cancer.Feb 01, 2012

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Pubmed Data : Curr Mol Med. 2012 Feb 1 ;12(2):163-76. PMID: 22280355

Topical epigallocatechin-3-gallate in the treatment of vitiligo.Jul 31, 2021

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Pubmed Data : Australas J Dermatol. 2021 Aug ;62(3):e404-e407. Epub 2021 May 28. PMID: 34046892

Click here to read the entire abstract

Pubmed Data : Complement Ther Med. 2019 Aug ;45:234-241. Epub 2019 Jul 2. PMID: 31331567

Article Published Date : Jul 31, 2019

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Down Syndrome

[+]

Combinations of EGCG and anticancer compounds induced synergistic anticancer effects in vitro and in vivo experiments, and showed an average reduction in tumor volume by 70.3 %.Aug 31, 2015

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Pubmed Data : J Cancer Res Clin Oncol. 2015 Sep ;141(9):1511-22. Epub 2014 Dec 28. PMID: 25544670

Article Published Date : Aug 31, 2015

Study Type : Animal Study, Human In Vitro

Additional Links

Substances : Catechin , EGCG (Epigallocatechin gallate), Green Tea

Diseases : Cancers: All

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Cancer Stem Cells, Natural Substance/Drug Synergy

[+]

EGCG protected against the effects of Dihydrotestosterone (DHT) by altering the miRNA expression profile in human dermal papilla cells.May 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Biomater Sci. 2023 Oct 10 ;11(20):6862-6870. Epub 2023 Oct 10. PMID: 37646313

Article Published Date : Oct 09, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Coenzyme Q10, EGCG (Epigallocatechin gallate)

Diseases : Myocardial Infarction

Pharmacological Actions : Anti-Apoptotic, Cardioprotective

Additional Keywords : Natural Substance Synergy

[+]

The anti-cancer effect of epigallocatechin-3-O-gallate against multiple myeloma cells is potentiated by 5,7-dimethoxyflavone.Oct 31, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2024 Jul 20 ;16(14). Epub 2024 Jul 20. PMID: 39064787

Article Published Date : Jul 19, 2024

Study Type : Animal Study

Additional Links

Substances : Cryptoxanthin, EGCG (Epigallocatechin gallate)

Diseases : Obesity

Pharmacological Actions : Hepatoprotective

Additional Keywords : Anti-Obesity Agents, Natural Substance Synergy

[+]

The green tea polyphenol epigallocatechin-3-gallate attenuates age-associated muscle loss via regulation of miR-486-5p and myostatin.Jul 21, 2020

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Pubmed Data : Arch Biochem Biophys. 2020 Jul 22 ;692:108511. Epub 2020 Jul 22. PMID: 32710883

Pharmacological Actions : Bcl-2 protein down-regulation, Chemopreventive, Chemosensitizer

Additional Keywords : Natural Substance/Drug Synergy

[+]

Artificial tears containing epigallocatechin gallate and hyaluronic acid had a synergistic effect in the treatment of dry eye syndrome.Dec 31, 2015

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Pubmed Data : Phytother Res. 2019 Feb 11. Epub 2019 Feb 11. PMID: 30746789

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Efficacy of epigallocatechin gallate (EGCG) and its underlying mechanism in preventing bisphenol-A-induced metabolic disorders.May 04, 2024

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Pubmed Data : J Hazard Mater. 2024 May 5 ;469:134098. Epub 2024 Mar 21. PMID: 38522198

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Pubmed Data : PLoS One. 2017 ;12(1):e0169630. Epub 2017 Jan 19. PMID: 28103249

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Pubmed Data : Biochem Biophys Res Commun. 2019 Apr 16. Epub 2019 Apr 16. PMID: 31003767

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Pubmed Data : Food Chem Toxicol. 2016 May 8. Epub 2016 May 8. PMID: 27170490

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Pubmed Data : EMBO Rep. 2004 Apr ;5(4):418-22. Epub 2004 Mar 12. PMID: 15031715

Article Published Date : Mar 31, 2004

Study Type : Animal Study

Additional Links

Substances : Catechin , EGCG (Epigallocatechin gallate), Green Tea

Diseases : Anthrax

Pharmacological Actions : Anti-Apoptotic, Matrix Metalloproteinases Inhibitors

Additional Keywords : Anthrax Lethal Factor

[+]

EGCG could be useful for the prevention and treatment of rheumatoid arthritis and other inflammatory disorders.Dec 31, 2014

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Pubmed Data : Basic Clin Pharmacol Toxicol. 2015 Jan 27. Epub 2015 Jan 27. PMID: 25625183

Pubmed Data : Exp Ther Med. 2018 Jan ;15(1):1087-1092. Epub 2017 Nov 14. PMID: 29434699

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Autoimmune Thyroiditis, Thyroiditis: Autoimmune

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents

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EGCG has a protective effect on rat brain injury induced by middle cerebral artery occlusion.Dec 31, 2017

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Pubmed Data : Biomed Res Int. 2018 ;2018:6473580. Epub 2018 Mar 25. PMID: 29770336

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Middle Cerebral Artery Occlusion (MCAO)

Pharmacological Actions : Neuroprotective Agents

[+]

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EGCG inhibited SW780 bladder cancer tumor growth by down-regulation of NF-κB and MMP-9.Dec 19, 2016

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Pubmed Data : J Nutr Biochem. 2016 Dec 20 ;41:56-64. Epub 2016 Dec 20. PMID: 28040581

Article Published Date : Dec 19, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Bladder Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor

[+]

EGCG inhibits arsenic-induced inflammation and apoptosis through suppression of oxidative stress in mice.Apr 02, 2017

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Pubmed Data : Cell Physiol Biochem. 2017 Apr 3 ;41(5):1788-1800. Epub 2017 Apr 3. PMID: 28365685

Article Published Date : Apr 02, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Arsenic Poisoning

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Problem Substances : Arsenic

[+]

EGCG inhibits fibroid tumors in quail. Feb 01, 2008

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Pubmed Data : Nutr Res. 2008 Feb;28(2):92-7. PMID: 19083394

Article Published Date : Feb 01, 2008

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Fibroid Tumor, Fibroids: Uterine, Leiomyoma

Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

EGCG is a strong combination partner of gemcitabine reducing pancreatic cancer cell growth by suppressing glycolysis.Oct 04, 2019

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Pubmed Data : Cancers (Basel). 2019 Oct 5 ;11(10). Epub 2019 Oct 5. PMID: 31590367

Article Published Date : Oct 04, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Pancreatic Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Chemosensitizer

Additional Keywords : Cancer Glycolysis, Chemotherapeutic Synergy: Gemcitabine

[+]

EGCG is effective in inflammatory colitis because it reduces cellular and molecular inflammation, and reduces intestinal permeability.Jul 28, 2019

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Pubmed Data : Int J Mol Med. 2017 Nov 28. Epub 2017 Nov 28. PMID: 29207033

Article Published Date : Nov 27, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Asthma: Bronchial

Pharmacological Actions : Anti-Inflammatory Agents

[+]

EGCG may be useful for reducing hepatotoxicity associated with oxidative stressJun 20, 2017

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Pubmed Data : Oncotarget. 2017 Jun 21. Epub 2017 Jun 21. PMID: 28658663

Pubmed Data : Biomed Res. 2007 Oct;28(5):261-6. PMID: 16356650

Article Published Date : Oct 01, 2007

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Amyotrophic Lateral Sclerosis

[+]

EGCG may reduce atherosclerotic plaque and alleviate pathological damage in the cardiac tissue.Dec 31, 2021

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Pubmed Data : Contrast Media Mol Imaging. 2022 ;2022:8639139. Epub 2022 Jul 11. PMID: 35919501

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Coronary Artery Disease

Pharmacological Actions : Antioxidants, Cardioprotective, Heme oxygenase-1 up-regulation, Nrf2 activation

[+]

EGCG may regenerate the HOCl-production of MPO which is known to be impaired at chronic inflammatory diseases like RA.Dec 31, 2015

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Pubmed Data : Oncotarget. 2016 May 6. Epub 2016 May 6. PMID: 27167203

Article Published Date : May 05, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Colon Cancer

Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive

Additional Keywords : Dose Response, Epigenetic Modification In Cancer, Gene Expression Regulation

[+]

EGCG nanoparticles attenuate aluminum chloride induced neurobehavioral deficits.Dec 31, 2017

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Pubmed Data : Front Aging Neurosci. 2018 ;10:244. Epub 2018 Aug 13. PMID: 30150930

Pubmed Data : J Vet Sci. 2007 Jun;8(2):121-9. PMID: 17519564

Article Published Date : Jun 01, 2007

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cardiac Hypertrophy

[+]

EGCG promotes atherosclerotic lesion stability in apolipoprotein E-deficient mice.Jun 03, 2018

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Pubmed Data : Kardiol Pol. 2018 Jun 4. Epub 2018 Jun 4. PMID: 29862488

Article Published Date : Jun 03, 2018

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Coronary Artery Disease

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

EGCG promotes PRKCA expression to alleviate LPS-induced acute lung injury and inflammatory response.May 25, 2021

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Pubmed Data : Front Biosci (Landmark Ed). 2023 Dec 1 ;28(12):324. PMID: 38179734

Article Published Date : Nov 30, 2023

Study Type : Animal Study

Additional Links

Substances : Catechin , EGCG (Epigallocatechin gallate)

Diseases : Wound Healing

[+]

EGCG reversed GIO in rats by protecting osteoblasts by activating the Nrf2 signaling pathway.Dec 31, 2017

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Pubmed Data : Front Pharmacol. 2018 ;9:447. Epub 2018 May 9. PMID: 29867459

Article Published Date : Dec 31, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Osteoporosis

Pharmacological Actions : Antioxidants, Nrf2 activation, Osteoprotective

[+]

EGCG sensitizes breast cancer cells to paclitaxel in a mouse model of breast carcinoma.Jan 15, 2010

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Pubmed Data : Breast Cancer Res. 2010 Jan 15;12(1):R8. Epub 2010 Jan 15. PMID: 20078855

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Pubmed Data : Clin Exp Otorhinolaryngol. 2016 May 3. Epub 2016 May 3. PMID: 27136365

Article Published Date : May 02, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Chemotherapy and Radiation Toxicity

Pharmacological Actions : Radioprotective

Additional Keywords : Natural Substances Versus Drugs

[+]

EGCG treatment can decrease renal ischemia-reperfusion injury by suppressing inflammation and cell apoptosis.Jun 27, 2015

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Pubmed Data : Int Urol Nephrol. 2015 Jun 28. Epub 2015 Jun 28. PMID: 26122117

Pubmed Data : Cancer Res. 2006 May 15;66(10):5512-20. PMID: 16707481

Article Published Date : May 15, 2006

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Skin Diseases: Photo-Aging, Xeroderma Pigmentosum

[+]

EGCG, a green tea polyphenol, significantly interferes with androgen-independent prostate cancer in vivo. Jan 01, 2008

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Pubmed Data : Nutr Cancer. 2008;60(4):483-91. PMID: 18584482

Article Published Date : Jan 01, 2008

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Pubmed Data : Cancer Manag Res. 2019 ;11:2425-2439. Epub 2019 Mar 27. PMID: 30988640

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Pubmed Data : Viruses. 2021 12 17 ;13(12). Epub 2021 Dec 17. PMID: 34960802

Article Published Date : Jan 16, 2021

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Coronavirus Infection

Pharmacological Actions : Antiviral Agents

[+]

Epigallocatechin gallate alleviates high-fat diet-induced hepatic lipotoxicity.Dec 31, 2022

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Epigallocatechin gallate attenuates arsenic induced genotoxicity via regulation of oxidative stress.Jul 25, 2019

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Pubmed Data : Mol Biol Rep. 2019 Jul 26. Epub 2019 Jul 26. PMID: 31350662

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Epigallocatechin-3-gallate alleviates type 2 diabetes mellitus via β-cell function improvement and insulin resistance reduction.Mar 31, 2022

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Pubmed Data : Iran J Basic Med Sci. 2022 Apr ;25(4):483-488. PMID: 35656076

Article Published Date : Mar 31, 2022

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Diabetes Mellitus: Type 2, Insulin Resistance

Pharmacological Actions : Hypoglycemic Agents, Insulin Sensitizers

[+]

Epigallocatechin-3-gallate ameliorates atherosclerosis and modulates hepatic lipid metabolic gene expression.Dec 31, 2017

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Pubmed Data : Front Pharmacol. 2018 ;9:195. Epub 2018 Mar 9. PMID: 29593532

Epigallocatechin-3-gallate exerts protective effect on epithelial function.Jul 21, 2022

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Pubmed Data : Microvasc Res. 2022 Jul 22 ;144:104408. Epub 2022 Jul 22. PMID: 35878868

Article Published Date : Jul 21, 2022

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Venous Thrombosis

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants

[+]

Epigallocatechin-3-gallate improves cardiac hypertrophy and short-term memory deficits in a Williams-Beuren syndrome mouse model.Dec 31, 2017

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Pubmed Data : Molecules. 2023 Aug 30 ;28(17). Epub 2023 Aug 30. PMID: 37687170

Article Published Date : Aug 29, 2023

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cadmium Poisoning

Pharmacological Actions : Detoxifier

Problem Substances : Cadmium

[+]

Epigallocatechin-3-gallate reduces hepatic oxidative stress and lowers CYP-mediated bioactivation and toxicity of acetaminophen.Aug 09, 2019

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Pubmed Data : Food Chem Toxicol. 2024 Feb ;184:114340. Epub 2023 Dec 12. PMID: 38097001

Article Published Date : Jan 31, 2024

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : High Fat Diet, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants

[+]

Eriodictyol synergistically potentiates the anti-tumour effect of EGCG by amplifying 67LR-dependent signalling in MM cellsDec 31, 2014

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Green tea epigallocatechin-3-gallate attenuates Porphyromonas gingivalis-induced atherosclerosis.Jan 31, 2013

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Pubmed Data : Pathog Dis. 2013 Feb ;67(1):76-83. Epub 2012 Nov 15. PMID: 23620122

Article Published Date : Jan 31, 2013

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Atherosclerosis, Porphyromonas gingivalis

Pharmacological Actions : Anti-Inflammatory Agents, Heme oxygenase-1 up-regulation, MicroRNA modulator

Additional Keywords : Gene Expression Regulation

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Green tea extracts reversed the striatal oxidative stress and immunohistochemistry alterations in rats.Dec 31, 2014

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Pubmed Data : Oxid Med Cell Longev. 2017 ;2017:9032792. Epub 2017 Jul 26. PMID: 28814987

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : High Fat Diet, Kidney Damage

Pharmacological Actions : Renoprotective

[+]

Green tea polyphenols reduce autoimmune symptoms in a mouse model for human Sjogren's syndrome. Mar 01, 2007

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Pubmed Data : Autoimmunity. 2007 Mar;40(2):138-47. PMID: 17364504

Article Published Date : Mar 01, 2007

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Sjogren's Syndrome

[+]

Green tea polyphenols rescue of brain defects induced by overexpression of DYRK1A.Dec 31, 2008

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Pubmed Data : PLoS One. 2009 ;4(2):e4606. Epub 2009 Feb 26. PMID: 19242551

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Pubmed Data : Int J Radiat Biol. 2010 Sep 1. Epub 2010 Sep 1. PMID: 20807176

Article Published Date : Sep 01, 2010

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), NAC (N-acetyl-L-cysteine)

Diseases : Mobile Phone-Induced Oxidative Stress

Pharmacological Actions : Antioxidants

[+]

Neuroprotective effect of green tea extract (-)-epigallocatechin-3-gallate in a preformed fibril-induced mouse model of Parkinson's disease.Apr 02, 2024

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Pubmed Data : Neuroreport. 2024 Apr 3 ;35(6):421-430. Epub 2024 Mar 7. PMID: 38526966

Article Published Date : Apr 02, 2024

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Neurodegenerative Diseases, Parkinson's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

[+]

Obesity may increase susceptibility to chronic pain often due to poor diet.Dec 31, 2017

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Pubmed Data : Eur J Pain. 2018 08 ;22(7):1203-1213. Epub 2018 Mar 2. PMID: 29436058

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Curcumin, EGCG (Epigallocatechin gallate), Ginseng, Resveratrol, Sulforaphane

Diseases : Chronic Pain, Inflammation, Obesity

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Inflammatory Diet, Risk Factors

[+]

Oral consumption of the green tea polyphenol EGCG improves disease paramaters in a mouse model of human Sjogren's syndrome. Oct 24, 2008

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Pubmed Data : Life Sci. 2008 Oct 24;83(17-18):581-8. Epub 2008 Sep 6. PMID: 18809413

Article Published Date : Oct 24, 2008

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Sjogren's Syndrome

[+]

Oral intake of green tea extract or its catechin constituents attenuates sodium iodate-induced retinal degeneration.Dec 31, 2015

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Pubmed Data : Int J Mol Sci. 2021 Feb 20 ;22(4). Epub 2021 Feb 20. PMID: 33672782

Article Published Date : Feb 19, 2021

Study Type : Animal Study

Pubmed Data : Phytomedicine. 2021 Nov ;92:153754. Epub 2021 Sep 14. PMID: 34607205

Pubmed Data : Nutrients. 2017 Jul 19 ;9(7). Epub 2017 Jul 19. PMID: 28753942

Article Published Date : Jul 18, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea, Quercetin

Diseases : High Fat Diet, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Gene Expression Regulation

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Consumption of green tea EGCG resulted in a significant reduction of low-density lipoprotein cholesterol.Jun 19, 2016

Sulforaphane and EGCG restore estrogen receptor expression by modulating epigenetic events in the breast cancer cell line MDA-MB-231.Oct 17, 2017

The effects of green tea on weight loss and weight maintenance.Aug 31, 2009

Therapeutic effects of epigallocatechin-3-gallate for inflammatory bowel disease.May 31, 2024

A presurgical study of lecithin formulation of green tea extract in women with early breast cancer.May 31, 2017

Addition of epigallocatechin gallate 400 mg to sofosbuvir 400 mg + daclatisvir 60 mg in in treatment of patients with chronic hepatitis C.Jan 18, 2019

Administration of polyphenon E resulted in a therapeutic benefit for patients who were refractory to 5-aminosalicylic and/or azathioprine.Jul 31, 2013

AverTeaX formulation containing lipophilic catechins effectively inhibited herpes simplex labialis infection with clinical significance.Nov 30, 2015

Both both zonal priming and direct EGCG application in scar therapy has positive effects on scar thickness, erythema, hydration and elasticity.Feb 25, 2019

Both EGCG and green tea could be used as alternatives to chlorhexidine-based mouthwashes.Apr 18, 2020

Cysteamine plus epigallocatechin gallate can be used for autophagy-dependent rescue of class II-mutated CFTR.Mar 31, 2016

Decaffeinated green tea extract resulted in significant reductions in lesions located on the nose, perioral area and chin.Mar 31, 2016

Decreases in inflammatory levels in patients with multiple sclerosis after treatment with epigallocatechin gallate and coconut oil.Sep 15, 2021

Efficacy and safety of EGCG oxygen nebulization inhalation in the treatment of COVID-19 pneumonia patients with cancer.Apr 16, 2024

Efficacy of EGCG in preventing dermatitis in patients with breast cancer receiving postoperative radiotherapy.May 31, 2022

EGCG activated AMPK and insulin pathways, thereby promoting glycolysis, glycogen, and protein synthesis and inhibiting fatty acid and cholesterol synthesis.Nov 16, 2021

EGCG and coconut oil improve state anxiety and functional capacity in patients with multiple sclerosis.Jan 22, 2020

EGCG and cognitive training for 12 months led to an improving of visual recognition memory, inhibitory control, and adaptive behaviour.Jun 30, 2016

EGCG decreased skeletal muscle lactate concentrations in overweight individuals, suggesting a shift towards a more oxidative muscle phenotype.Dec 31, 2014

EGCG enhances fat oxidation in men and may contribute to the anti-obesity effects of green tea. Oct 22, 2010

EGCG given to patients with multiple sclerosis over 12 weeks improved muscle metabolism during moderate exercise to a greater extent in men than in women.Feb 28, 2015

EGCG supplementation may be improved blood pressure, lipid profile, AIP, and oxidative status in patients with T2DM.Dec 24, 2020

Epigallocatechin gallate could potentially be used as a supplement of traditional rt-PA treatment among stroke patients.Dec 08, 2016

Epigallocatechin gallate decreases plasma triglyceride, blood pressure, and serum kisspeptin in obese human subjects.Jan 11, 2020

Epigallocatechin gallate enhances sympathetic heart rate variability and decreases blood pressure in obese subjects.Sep 15, 2024

Epigallocatechin gallate enhances treatment efficacy of oral nifedipine against pregnancy-induced severe pre-eclampsia.Jan 31, 2018

Epigallocatechin-3-gallate mouthwash protects mucosa from radiation-induced mucositis in head and neck cancer patients.Dec 31, 2019

Green tea catechins are effective in reducing atherosclerosis risk associated with oxidative stress.Dec 31, 2015

Green tea catechins may have a therapeutic role in the treatment of metabolic syndrome. Jan 01, 2009

Green tea polyphenon E and erlotinib combination was well tolerated in patients with APLs of the head and neck.Jan 14, 2020

High-dose green tea extract resulted in significant weight loss, reduced waist circumference, and a consistent decrease in total cholesterol and LDL plasma levels.May 28, 2015

Improvements in gait and balance in patients with multiple sclerosis after treatment with coconut oil and epigallocatechin gallate.Jan 22, 2023

It appears that EGCG should be taken without food in order to maximise its systemic absorption.Dec 31, 2014

Phase II trial of epigallocatechin-3-gallate in acute radiation-induced esophagitis for esophagus cancer.Dec 31, 2019

Supplementation with green tea extract significantly reduced circulating triglycerides and LDL-cholesterol concentrations.Nov 01, 2016

Tea polyphenol has potential to be a therapeutic adjuvant against human metastatic breast cancer.Feb 01, 2012

Tea polyphenols (primarily EGCG), significantly reduce PSA, Hepatocyte growth factor, VEG in men with prostate cancer. Jul 01, 2009

The administration of EGCG and coconut oil seems to decrease blood triglyceride levels.Oct 10, 2023

The association between green and black tea consumption on successful aging.May 14, 2019

The effect of (-)-epigallocatechin gallate as an adjunct to non-surgical periodontal treatment.May 02, 2022

The inhalation of tea catechin appears to suppress MRSA infection in the elderly. Feb 01, 2006

Topical EGCG may be an effective treatment for radiation-induced dermatitis and has acceptable toxicity.May 19, 2016

Topical epigallocatechin-3-gallate in the treatment of vitiligo.Jul 31, 2021

Topical green tea extract appears safe and effective in treating external anogenital warts. Jan 01, 2006

Twelve weeks of EGCG and resveratrol supplementation increased mitochondrial capacity and stimulated fat oxidation.May 17, 2016

Usage of and attitudes about green tea extract and epigallocathechin-3-gallate as a therapy in individuals with Down syndrome.Jul 31, 2019

Combinations of EGCG and anticancer compounds induced synergistic anticancer effects in vitro and in vivo experiments, and showed an average reduction in tumor volume by 70.3 %.Aug 31, 2015

EGCG protected against the effects of Dihydrotestosterone (DHT) by altering the miRNA expression profile in human dermal papilla cells.May 31, 2016

Epigallocatechin gallate suppresses Chlamydia pneumoniae mediated IgE responses.Jun 15, 2016

Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome.Jan 01, 2013

Panaxadiol and Epigallocatechin Gallate have a synergistic apoptotic effect on human colorectal cancer cells.May 08, 2012

Punicalagin and EGCG can rescue keratinocyte viability and attenuate the inflammatory responses of cells due to airborne particles.Mar 21, 2018

These results provide new evidence for the effectiveness of EGCG in vitiligo treatment.Sep 03, 2015

VEGF is a key molecular target for specific polyphenols found in tea, apples and cocoa which potently inhibit VEGF signalling and angiogenesis at physiological concentrations.Feb 28, 2015

A case of complete and durable molecular remission of chronic lymphocytic leukemia following treatment with epigallocatechin-3-gallate.Dec 31, 2014

Co-delivery of EGCG and melittin with self-assembled fluoro-nanoparticles for enhanced cancer therapy.Jun 04, 2023

EGCG disrupts the LIN28B/Let-7 interaction and reduces neuroblastoma aggressiveness.Apr 26, 2024

Epicatechin gallate blocked cellular foam formation in atherosclerosis.Mar 05, 2023

Epigallocatechin-3-gallate improves the quality of maternally aged oocytes.Nov 26, 2023

Synergetic EGCG and coenzyme Q10 DSPC liposome nanoparticles protect against myocardial infarction.Oct 09, 2023

The anti-cancer effect of epigallocatechin-3-O-gallate against multiple myeloma cells is potentiated by 5,7-dimethoxyflavone.Oct 31, 2023

Epigallocatechin gallate but not catechin prevents nonalcoholic steatohepatitis in mice similar to green tea extract while differentially affecting the gut microbiota.Jun 19, 2020

Sex-specific oxidative damage effects induced by BPA and its analogs on primary hippocampal neurons attenuated by EGCG.Sep 27, 2020

Synergistic Effect of β-cryptoxanthin and epigallocatechin gallate on obesity reduction. Jul 19, 2024

The green tea polyphenol epigallocatechin-3-gallate attenuates age-associated muscle loss via regulation of miR-486-5p and myostatin.Jul 21, 2020

"Amelioration of influenza virus-induced reactive oxygen species formation by epigallocatechin gallate derived from green tea."Nov 30, 2012

"Green tea catechins ameliorates adipose Insulin resistance by improving oxidative stress."Feb 11, 2012

"Green tea epigallocatechin-3-gallate (EGCG) promotes neural progenitor cell proliferation and sonic hedgehog pathway activation during adult hippocampal neurogenesis."Jul 31, 2012

"Green tea epigallocatechin-3-gallate attenuates Porphyromonas gingivalis-induced atherosclerosis."Sep 10, 2012

(-)-Epigallocatechin-3-gallate (EGCG) can inhibit the proliferation and invasiveness and induce apoptosis in nasopharyngeal carcinoma cells.Dec 31, 2014

A combination of nutrients improves cognitive functioning while decreasing Alzheimer disease neuropathology in an animal model.Jan 01, 2010

A major metabolite of EGCG increased the activity of CD4(+) T cells and enhanced the cytotoxic activity of NK cells in vivo.May 10, 2016

EGCG (Epigallocatechin gallate)

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820 Abstracts with EGCG (Epigallocatechin gallate) Research