EGCG (Epigallocatechin gallate)

Name	AC	CK
Obesity	31	111
Oxidative Stress	33	70
Breast Cancer	29	61
Cancers: All	39	59
Inflammation	32	55
Multiple Sclerosis	8	53
Alzheimer's Disease	29	37
Lung Cancer	28	37
Down Syndrome	8	34
Diabetes Mellitus: Type 2	13	30
Head and Neck Cancer	9	30
Inflammatory Bowel Diseases	7	28
Coronavirus Infection	24	26
High Fat Diet	13	26
Prostate Cancer	16	26
Breast Cancer: Triple Negative	6	25
Atherosclerosis	8	22
Hypertension	4	22
High Cholesterol	1	20
Liver Cancer	17	20
Neurodegenerative Diseases	16	20
Parkinson's Disease	15	20
Aging	6	19
Cancers: Drug Resistant	15	17
Metabolic Syndrome X	6	17
Wound Healing	5	16
Hyperlipidemia	4	15
Melanoma	11	15
Nonalcoholic fatty liver disease (NAFLD)	8	15
Pancreatic Cancer	12	15
Stroke: Attenuation/Recovery	4	15
Vitiligo	2	15
Esophageal Cancer	5	14
Lipid Peroxidation	3	14
Lipopolysaccharide-Induced Toxicity	10	14
Radiation	3	14
Arsenic Poisoning	7	13
Periodontal Diseases	3	13
Pre-Eclampsia	3	13
Brain Inflammation	9	12
Brain Ischemia	2	12
Cervical Cancer	13	12
Chemotherapy and Radiation Toxicity	2	12
Colorectal Cancer	7	12
Coronavirus Disease (Covid-19)	3	12
Diabetic Complications	8	12
Hepatitis C	3	12
Breast Cancer: Metastatic	2	11
MRSA	2	11
Ovarian Cancer	11	11
Scars	2	11
Staphylococcus aureus: Methicillin-resistant (MRSA)	2	11
Acne	1	10
Anogenital Warts	1	10
Bisphenol Toxicity	6	10
Cardiovascular Disease: Prevention	1	10
Cholesterol: High	1	10
Cystic Fibrosis	1	10
Dental Caries: Children	1	10
Dermatitis	1	10
Elderly: Age Specific Diseases	1	10
Genital Warts	1	10
Herpes Simplex Virus Type 1	1	10
Human Papillomavirus (HPV)	8	10
Insulin Resistance	5	10
Multiple Sclerosis: Relapsing-Remitting	1	10
Myocardial Ischemia	7	10
Overweight	1	10
Pneumonia	1	10
Prostate: PSA Doubling	1	10
Radiation Induced Illness: Mucositis	1	10
Radiotherapy	1	10
Rheumatoid Arthritis	7	10
Triglycerides: Elevated	1	10
Ulcerative Colitis	1	10
Cardiac Hypertrophy	5	9
Chemically-Induced Liver Damage	5	9
Colon Cancer	7	9
Endometriosis	7	9
Multiple Myeloma	6	9
Air Pollution Linked Toxicity	3	8
Bladder Cancer	6	8
Chemotherapy-Induced Toxicity: Doxorubicin	6	8
Diabetic Nephropathy	5	8
Kidney Damage	4	8
Myocardial Fibrosis	4	8
Autoimmune Diseases	5	7
Cardiovascular Diseases	6	7
Escherichia coli Infections	7	7
Influenza A	6	7
Osteoporosis	4	7
Periodontitis	4	7
Pseudomonas aeruginosa	6	7
Sjogren's Syndrome	5	7
Advanced Glycation End products (AGE)	4	6
Asthma	3	6
Cancer Metastasis	4	6
Chemotherapy-Induced Toxicity: Cisplatin	3	6
Diabetes Mellitus: Type 1	4	6
HIV Infections	6	6
Hyperglycemia	3	6
Hyperuricemia	3	6
Muscle Atrophy	3	6
Myocardial Infarction	3	6
Smoking	4	6
Steptococcus Mutans Infections	6	6
Alopecia	1	5
Amyotrophic Lateral Sclerosis	3	5
Brain: Oxidative Stress	4	5
Cadmium Poisoning	3	5
Cancers: Multi-Drug Resistant	5	5
Carcinoma: Non-Small-Cell Lung	4	5
Cataract	4	5
Chlamydia pneumoniae	1	5
Colitis	3	5
Coronary Artery Disease	3	5
Dysbiosis	3	5
Endotoxemia	3	5
Gastric Cancer	4	5
Glioblastoma	5	5
Hair Loss	1	5
Heart Failure	3	5
Kidney Damage: Chemically-Induced	3	5
Leiomyoma	3	5
Neuroblastoma	3	5
Oral Cancer	5	5
Prostatic Hyperplasia: Benign	3	5
Acetaminophen (Tylenol) Toxicity	2	4
Alcoholic Liver Disease	2	4
Anxiety	2	4
Chemotherapy-Induced Toxicity: Cyclophosphamide	2	4
Endometrial Cancer	4	4
Erectile Dysfunction	2	4
Hepatitis B	4	4
High Sugar Diet	3	4
Kidney Diseases	2	4
Liver Damage	2	4
Liver Damage: Drug-Induced	2	4
Liver Fibrosis	3	4
Lung Injury: Acute	2	4
Middle Cerebral Artery Occlusion (MCAO)	2	4
Nicotine/Tobacco Toxicity	2	4
Porphyromonas gingivalis	2	4
Salmonella Infections	3	4
Squamous cell carcinoma	3	4
Staphylococcus aureus infection	4	4
Acinetobacter baumannii infection	3	3
Acrylamide-induced toxicity	2	3
Anthrax	2	3
Atrial Fibrillation	2	3
Burns	2	3
Cachexia: Cancer	2	3
Cancer Stem Cells	3	3
Carcinoma: Small Cell Lung	2	3
Chemotherapy-Induced Toxicity: Gentamicin	2	3
Chronic Lymphocytic Leukemia	2	3
Clostridium Infections	2	3
Depression	2	3
Dry Eye Syndromes	2	3
Fatty Liver	2	3
Fibrosis	2	3
Fluoride Toxicity	2	3
High Fructose Diet	2	3
Hypoglycemia	2	3
Hypoxia	3	3
Infertility: Female	1	3
Iron Overload	2	3
Kidney Cancer	3	3
Kidney Fibrosis	3	3
Liver Cancer: Prevention	2	3
Lymphoma	2	3
Metabolic Diseases	2	3
Nasopharyngeal Cancer	2	3
Neuropathic Pain	2	3
Osteoarthritis	3	3
Osteosarcoma	3	3
Pulmonary Fibrosis	2	3
Skin Cancer	3	3
Stroke: Ischemic	2	3
Thyroid Cancer	2	3
Aging Skin	1	2
Alcohol Toxicity	1	2
Aluminum Toxicity	1	2
Aneurysm: Aortic	1	2
Arthritis	1	2
Arthritis: Rheumatoid	2	2
Asbestos Toxicity	2	2
Asthma: Bronchial	1	2
Autoimmune Thyroiditis	1	2
Benzo[a]pyrene-induced Toxicity	1	2
Bone Cancer	1	2
Brain Cancer	2	2
Brain Injury: Hippocampal Damage	1	2
C-Reactive Protein	1	2
Cancers	2	2
Cardiac Mortality	1	2
Cardiomyopathy: Restrictive	1	2
Cerebral Hypoperfusion	1	2
Cerebral Ischemia	1	2
Chemotherapy	1	2
Chemotherapy-Induced Kidney Damage	1	2
Chemotherapy-Induced Toxicity: Bleomycin	1	2
Chemotherapy-Induced Toxicity: Irinotecan	1	2
Chikungunya Virus	2	2
Cholangiocarcinoma	2	2
Cholecystitis	1	2
Chronic Fatigue Syndrome	1	2
Chronic Pain	1	2
Cognitive Decline/Dysfunction	1	2
Coronary Bypass Surgery	1	2
DNA damage	1	2
Diabetes Mellitus: Type 1: Prevention	1	2
Diabetes: Cardiovascular Illness	1	2
Diabetes: Cataract	1	2
Diabetes: Oxidative Stress	1	2
Diabetic Retinopathy	2	2
Drug Toxicity: Methotrexate	1	2
Encephalomyelitis	2	2
Endothelial Dysfunction	2	2
Epilepsy	1	2
Fetal Origin of Adult Disease	1	2
Fibroid Tumor	1	2
Fibroids: Uterine	1	2
Fish Diseases	1	2
Gallbladder Inflammation	1	2
Gallstones	1	2
Gastrointestinal Inflammation	1	2
Gastrointestinal Stromal Tumors	1	2
Gestational Diabetes	1	2
Gingivitis	1	2
Glaucoma	1	2
Glioma	2	2
Glomerulonephritis	1	2
Gout	1	2
Graft vs Host Disease	1	2
H1N1 Infection	2	2
Herpes Simplex Virus Type 2	2	2
Huntington Disease	1	2
Hydrogen Peroxide Induced Toxicity	2	2
Infection: Antibiotic Resistant	2	2
Inflammation: Neutrophil-Mediated	1	2
Influenza	2	2
Influenza B	2	2
Ischemia	1	2
Learning disorders	1	2
Leiomyosarcoma	2	2
Leukemia: Acute promyelocytic leukemia	2	2
Leukemia: Chronic Lymphocytic Leukemia (CLL)	2	2
Leukemia: T-cell acute Lymphoblastic	2	2
Lung Damage	1	2
Lung Infection	1	2
Melanoma: Metastatic	1	2
Memory Loss	1	2
Microplastic Toxicity	1	2
Mitochondrial Dysfunction	2	2
Mobile Phone-Induced Oxidative Stress	1	2
Morphine Tolerance/Dependence	1	2
Muscular Dystrophies	1	2
Neural Tube Defects	1	2
Non-Hodgkin's lymphoma: B Cell	2	2
Obstructive Nephropathy	1	2
Pancreatitis	1	2
Peripheral Nerve Diseases	1	2
Puberty: Precocious	1	2
Respiratory Diseases	2	2
Retinal Diseases	1	2
Rhabdomyosarcoma	2	2
Sciatica	1	2
Sepsis	1	2
Silicosis	1	2
Skin Diseases: Photo-Aging	1	2
Tardive Dyskinesia	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Thyroiditis: Autoimmune	1	2
Tongue Cancer	1	2
Uveitis	1	2
Venous Thrombosis	1	2
Williams Syndrome	1	2
Wound Healing: Delayed	1	2
Xeroderma Pigmentosum	1	2
Acanthamoeba infection	1	1
Acid Reflux	1	1
Aflatoxicosis	1	1
Aging: Brain	1	1
Allergies	1	1
Amyloidosis	1	1
Animal Diseases: Porcine Circovirus Type 2 (PCV2)	1	1
Avian Influenza	1	1
Bacterial Infections	1	1
Bacterial Infections and Mycoses	1	1
Barrett Esophagus	1	1
Bile Duct Cancer	1	1
Breast Cancer Stem Cells	1	1
Burkitt Cell Leukemia	1	1
Candida Infection	1	1
Cerebral Stroke	1	1
Cholesterol: Oxidation	1	1
Choriocarcinoma	1	1
Chronic Myeloid Leukemia	1	1
Degenerative Disk Disease	1	1
Dengue	1	1
Dengue Fever	1	1
Dental Caries	1	1
Diabetes: Liver Disease	1	1
Drug-Induced Toxicity: Gastrointestinal	1	1
Drug-Induced Toxicity: Indomethacin	1	1
Ebola Virus Infections	1	1
Encephalitis: Japanese	1	1
Enterovirus	1	1
Epstein-Barr Virus Infections	1	1
Eye Diseases	1	1
Fibrosis: Liver	1	1
Follicular Lymphoma	1	1
Food Allergies	1	1
Foodborne Pathogens: Prevention/Food Preservation	1	1
Fungal Infections: Biofilm Formation/Resistance	1	1
Gastrointestinal Diseases	1	1
H3N2 Infection	1	1
HSV-1	1	1
HSV-2	1	1
Halitosis	1	1
Hearing Loss	1	1
Helicobacter Pylori Infection	1	1
Human T-Cell Lymphotrophic Virus type 1 associated disease	1	1
Intestinal Permeability	1	1
Keloid	1	1
Klebsiella Infections	1	1
Leaky Gut Syndrome	1	1
Leukemia: Acute myelogenous leukemia (AML)	1	1
Leukemia: Chronic myelogenous leukemia (CML)	1	1
Liver Cancer: Metastatic	1	1
Liver Diseases	1	1
Lung Injury: Smoke-Induced	1	1
Mastocytoma	1	1
Medulloblastoma	1	1
Mesothelioma	1	1
Mitochondrial Diseases	1	1
Multiple System Atrophy (MSA)	1	1
Nasopharyngeal Cancer Stem Cells	1	1
Neurologic Disorders	1	1
Non-Small-Cell Lung Carcinoma	1	1
Norovirus	1	1
Osteomyelitis	1	1
Pesticide Toxicity	1	1
Pituitary Diseases	1	1
Polio	1	1
Pregnancy Complications	1	1
Promyelocytic leukemia	1	1
Prostate Cancer: Prevention	1	1
Rabies	1	1
Retinitis Pigmentosa	1	1
Ricin Toxicity	1	1
Salivary Gland Adenoid Cystic Carcinoma.	1	1
Spinal Cord Injuries	1	1
Staphylococcus epidermidis	1	1
Stomach Cancer	1	1
Streptococcus Infections	1	1
Streptococcus pneumoniae infection	1	1
Subarachnoid hemorrhage	1	1
Swine Flu Associated Virus	1	1
T-Cell Mediated Diseases	1	1
Testicular Cancer	1	1
Thrombocytopenia	1	1
Viral Infections	1	1
West Nile Fever	1	1
Zika Virus	1	1

Name	AC	CK
Anti-Inflammatory Agents	125	229
Antioxidants	120	208
Antiproliferative	105	166
Apoptotic	99	145
Neuroprotective Agents	70	119
Hypolipidemic	17	72
Antiviral Agents	51	70
Chemopreventive	49	69
Cardioprotective	33	60
Gastrointestinal Agents	19	60
Interleukin-6 Downregulation	19	60
Anti-Apoptotic	35	54
Tumor Necrosis Factor (TNF) Alpha Inhibitor	29	53
Interleukin-1 beta downregulation	18	52
MicroRNA modulator	34	48
Radioprotective	8	47
Anti-metastatic	28	43
Anticholesteremic Agents	4	42
Hepatoprotective	23	41
Immunomodulatory	27	40
Nrf2 activation	23	39
Anticarcinogenic Agents	23	38
Anti-Bacterial Agents	25	36
Chemosensitizer	25	35
NF-kappaB Inhibitor	25	35
Antihypertensive Agents	4	31
Chemotherapeutic	27	31
Renoprotective	15	27
Hypoglycemic Agents	9	25
Anti-Fibrotic	15	23
Heme oxygenase-1 up-regulation	12	21
Chemoprotective Agents	13	20
Antimicrobial	8	19
Angiogenesis Inhibitors	12	18
Matrix metalloproteinase-2 (MMP-2) inhibitor	7	18
Antineoplastic Agents	12	15
Autophagy Up-regulation	6	15
Anti-Anxiety Agents	3	14
Anti-Angiogenic	9	13
Cell cycle arrest	12	13
Matrix metalloproteinase-9 (MMP-9) inhibitor	3	13
Vascular Endothelial Growth Factor Inhibitors	6	13
Interleukin-8 downregulation	7	12
Vascular Endothelial Growth Factor Regulator	3	12
Radiosensitizer	2	11
Tumor Suppressor Protein p53 Upregulation	8	11
Dermatologic Agents	1	10
Hepatocyte growth factor (HGF) inhibitor	1	10
Thermogenic	1	10
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	5	9
Cyclooxygenase 2 Inhibitors	6	7
Anti-Glycation Agents	4	6
Immunomodulatory: Th17 downregulation	3	6
Multidrug Resistance Gene Modulators	6	6
Osteoprotective	4	6
Quorum Sensing Inhibition	5	6
Bcl-2 protein down-regulation	4	5
Gastroprotective	3	5
Interleukin-18 down-regulation	3	5
Malondialdehyde Down-regulation	3	5
NF-E2-Related Factor-2 (Nrf2) Modulator	3	5
Neuritogenic	4	5
Wnt/β-catenin signaling pathway modulation	4	5
Anti-Adipogenic	3	4
Anti-HIV Agents	4	4
Autophagy Inhibitors	3	4
Cytoprotective	3	4
Hypoxia-inducible factor-1 (HIF-1) inhibitor	2	4
Interleukin-10 upregulation	2	4
Interleukin-17 downregulation	2	4
P21 Activation	2	4
Prophylactic Agents	3	4
Regenerative	3	4
Telomerase Inhibitor	4	4
Uricosuric Agents	2	4
Anti-Cachexic Agents	2	3
Anti-Proliferative	3	3
Antidepressive Agents	2	3
Brain-derived neurotrophic factor modulator	2	3
Enzyme Inhibitors	3	3
Epidermal growth factor receptor (EGFR) inhibitor	2	3
Fertility Agents: Female	1	3
Gluconeogenesis Inhibitor	2	3
Glutathione Upregulation	2	3
STAT3 Inhibitor	2	3
Wnt/β-catenin pathway down-regulation	2	3
Aldose reductase inhibitor	1	2
Analgesics	2	2
Anti-Asthmatic Agents	1	2
Antinoceceptive	1	2
Appetite Depressants	1	2
Calcium Desensitizer	1	2
Detoxifier	1	2
Genoprotective	1	2
Histone deacetylase inhibitor	2	2
Immunostimulatory	1	2
Insecticidal	1	2
Insulin Sensitizers	1	2
Interleukin-2 Downregulation	1	2
Interleukin-4 downregulation	1	2
Matrix Metalloproteinases Inhibitors	1	2
Neurogenesis	1	2
Neurorestorative	1	2
Pancreato Protective Agents	2	2
Reverse Transcriptase Inhibitors	2	2
Superoxide Dismutase Up-regulation	1	2
Telomere Protective	1	2
Transforming growth factor beta (TGF-β) inhibitor	2	2
Tumor Necrosis Factor (TNF) Alpha Enhancer	1	2
Vascular Endothelial Growth Factor A Inhibitor	1	2
Vasodilator Agents	1	2
Viral Hemagglutinin Inhibitor	2	2
Xanthine oxidase inhibitor	1	2
AMP-activated protein kinase modulation	1	1
Adiponectin upregulation	1	1
Alpha-amylase inhibitor	1	1
Alpha-glucosidase inhibitor	1	1
Angiotensin-Converting Enzyme Inhibitors	1	1
Anti-Allergic Agents	1	1
Antifungal Agents	1	1
Antiparasitic Agents	1	1
Cell Differentiation Inducer	1	1
Chemotherapeuticm	1	1
Cyclooxygenase 1 Inhibitor	1	1
Drug synergy	1	1
Interleukin-10 downregulation	1	1
Ionophores	1	1
Iron Chelating Agents	1	1
Lactate Dehydrogenase A Inhibitor	1	1
Neurominidase Inhibitor	1	1
P38 Mitogen-Activated Protein Kinase Modulator	1	1
Prostaglandin Antagonists	1	1
Proteasome Inhibitors	1	1
Proton Pump Inhibitor	1	1
STAT3-NFκB Signaling: downregulation	1	1

[+]

Consumption of green tea EGCG resulted in a significant reduction of low-density lipoprotein cholesterol.Jun 19, 2016

Click here to read the entire abstract

Pubmed Data : Int J Food Sci Nutr. 2016 Jun 20:1-8. Epub 2016 Jun 20. PMID: 27324590

Article Published Date : Jun 19, 2016

Study Type : Meta Analysis

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : High Cholesterol

Pharmacological Actions : Anticholesteremic Agents

[+]

Sulforaphane and EGCG restore estrogen receptor expression by modulating epigenetic events in the breast cancer cell line MDA-MB-231.Oct 17, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutrigenet Nutrigenomics. 2017 Oct 18 ;10(3-4):126-135. Epub 2017 Oct 18. PMID: 29040973

Article Published Date : Oct 17, 2017

Study Type : Meta Analysis, Review

Additional Links

Substances : EGCG (Epigallocatechin gallate), Sulforaphane

Diseases : Breast Cancer: Triple Negative

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Epigenetic Modification In Cancer

[+]

The effects of green tea on weight loss and weight maintenance.Aug 31, 2009

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Obes (Lond). 2009 Sep ;33(9):956-61. Epub 2009 Jul 14. PMID: 19597519

Article Published Date : Aug 31, 2009

Study Type : Meta Analysis

Additional Links

Substances : Catechin , EGCG (Epigallocatechin gallate), Green Tea

Diseases : Obesity

Additional Keywords : Anti-Obesity Agents

[+]

Therapeutic effects of epigallocatechin-3-gallate for inflammatory bowel disease.May 31, 2024

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2024 Jun ;128:155408. Epub 2024 Feb 2. PMID: 38503153

Article Published Date : May 31, 2024

Study Type : Meta Analysis

Additional Links

Substances : Catechin , EGCG (Epigallocatechin gallate)

Diseases : Inflammatory Bowel Diseases, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation

[+]

A presurgical study of lecithin formulation of green tea extract in women with early breast cancer.May 31, 2017

Click here to read the entire abstract

Pubmed Data : Cancer Prev Res (Phila). 2017 Jun ;10(6):363-370. Epub 2017 Apr 11. PMID: 28400479

Article Published Date : May 31, 2017

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Breast Cancer

Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative

Additional Keywords : Plant Extracts

[+]

Addition of epigallocatechin gallate 400 mg to sofosbuvir 400 mg + daclatisvir 60 mg in in treatment of patients with chronic hepatitis C.Jan 18, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2019 09 19 ;9(1):13593. Epub 2019 Sep 19. PMID: 31537880

Article Published Date : Jan 18, 2019

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Hepatitis C

Pharmacological Actions : Antiviral Agents

Additional Keywords : Natural Substance/Drug Synergy

[+]

Administration of polyphenon E resulted in a therapeutic benefit for patients who were refractory to 5-aminosalicylic and/or azathioprine.Jul 31, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Inflamm Bowel Dis. 2013 Aug ;19(9):1904-12. PMID: 23846486

Article Published Date : Jul 31, 2013

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Ulcerative Colitis

Pharmacological Actions : Gastrointestinal Agents

[+]

AverTeaX formulation containing lipophilic catechins effectively inhibited herpes simplex labialis infection with clinical significance.Nov 30, 2015

Click here to read the entire abstract

Pubmed Data : Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Dec ;120(6):717-24. Epub 2015 Sep 5. PMID: 26548726

Article Published Date : Nov 30, 2015

Study Type : Human Study

Additional Links

Substances : Catechin , EGCG (Epigallocatechin gallate)

Diseases : Herpes Simplex Virus Type 1

Pharmacological Actions : Antiviral Agents

[+]

Both both zonal priming and direct EGCG application in scar therapy has positive effects on scar thickness, erythema, hydration and elasticity.Feb 25, 2019

Click here to read the entire abstract

Pubmed Data : J Invest Dermatol. 2019 Feb 26. Epub 2019 Feb 26. PMID: 30822414

Article Published Date : Feb 25, 2019

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Scars, Wound Healing

[+]

Both EGCG and green tea could be used as alternatives to chlorhexidine-based mouthwashes.Apr 18, 2020

Click here to read the entire abstract

Pubmed Data : Arch Oral Biol. 2020 Apr 19 ;114:104727. Epub 2020 Apr 19. PMID: 32361019

Article Published Date : Apr 18, 2020

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Dental Caries: Children

Pharmacological Actions : Antimicrobial

Additional Keywords : Mouthwash

[+]

Cysteamine plus epigallocatechin gallate can be used for autophagy-dependent rescue of class II-mutated CFTR.Mar 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cell Death Differ. 2016 Apr 1. Epub 2016 Apr 1. PMID: 27035618

Article Published Date : Mar 31, 2016

Study Type : Animal Study, Human Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cystic Fibrosis

Pharmacological Actions : Anti-Inflammatory Agents, Autophagy Up-regulation

[+]

Decaffeinated green tea extract resulted in significant reductions in lesions located on the nose, perioral area and chin.Mar 31, 2016

Click here to read the entire abstract

Pubmed Data : Complement Ther Med. 2016 Apr ;25:159-63. Epub 2016 Mar 7. PMID: 27062963

Article Published Date : Mar 31, 2016

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Acne

Additional Keywords : Plant Extracts

[+]

Decreases in inflammatory levels in patients with multiple sclerosis after treatment with epigallocatechin gallate and coconut oil.Sep 15, 2021

Click here to read the entire abstract

Pubmed Data : Nutrients. 2021 Sep 16 ;13(9). Epub 2021 Sep 16. PMID: 34579104

Article Published Date : Sep 15, 2021

Study Type : Human Study

Additional Links

Substances : Coconut Oil, EGCG (Epigallocatechin gallate)

Diseases : Inflammation, Multiple Sclerosis, Obesity

Pharmacological Actions : Antioxidants

Additional Keywords : Anti-Obesity Agents

[+]

Efficacy and safety of EGCG oxygen nebulization inhalation in the treatment of COVID-19 pneumonia patients with cancer.Apr 16, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Cancer. 2024 Apr 17 ;24(1):486. Epub 2024 Apr 17. PMID: 38632501

Article Published Date : Apr 16, 2024

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cancers: All, Coronavirus Disease (Covid-19), Pneumonia

[+]

Efficacy of EGCG in preventing dermatitis in patients with breast cancer receiving postoperative radiotherapy.May 31, 2022

Click here to read the entire abstract

Pubmed Data : JAMA Dermatol. 2022 Jun 1. Epub 2022 Jun 1. PMID: 35648426

Article Published Date : May 31, 2022

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Breast Cancer, Dermatitis, Radiotherapy

Pharmacological Actions : Radioprotective

[+]

EGCG activated AMPK and insulin pathways, thereby promoting glycolysis, glycogen, and protein synthesis and inhibiting fatty acid and cholesterol synthesis.Nov 16, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2021 Nov 17 ;13(11). Epub 2021 Nov 17. PMID: 34836374

Article Published Date : Nov 16, 2021

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Hyperlipidemia

Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic

Additional Keywords : Plant Extracts

[+]

EGCG and coconut oil improve state anxiety and functional capacity in patients with multiple sclerosis.Jan 22, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2020 Jan 23 ;12(2). Epub 2020 Jan 23. PMID: 31979305

Article Published Date : Jan 22, 2020

Study Type : Human Study

Additional Links

Substances : Coconut Oil, EGCG (Epigallocatechin gallate)

Diseases : Multiple Sclerosis

Pharmacological Actions : Anti-Anxiety Agents, Anti-Inflammatory Agents, Interleukin-6 Downregulation

[+]

EGCG and cognitive training for 12 months led to an improving of visual recognition memory, inhibitory control, and adaptive behaviour.Jun 30, 2016

Click here to read the entire abstract

Pubmed Data : Lancet Neurol. 2016 Jul ;15(8):801-10. PMID: 27302362

Article Published Date : Jun 30, 2016

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Down Syndrome

Pharmacological Actions : Neuroprotective Agents

[+]

EGCG decreased skeletal muscle lactate concentrations in overweight individuals, suggesting a shift towards a more oxidative muscle phenotype.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2015 ;5:17896. Epub 2015 Dec 9. PMID: 26647963

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Additional Keywords : Supplementation

[+]

EGCG enhances fat oxidation in men and may contribute to the anti-obesity effects of green tea. Oct 22, 2010

Click here to read the entire abstract

Pubmed Data : J Biol Chem. 2010 Oct 22;285(43):33520-8. Epub 2010 Aug 18. PMID: 17906192

Article Published Date : Oct 22, 2010

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Obesity, Overweight

Pharmacological Actions : Thermogenic

[+]

EGCG given to patients with multiple sclerosis over 12 weeks improved muscle metabolism during moderate exercise to a greater extent in men than in women.Feb 28, 2015

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2015 Mar ;101(3):487-95. Epub 2015 Jan 14. PMID: 25733633

Article Published Date : Feb 28, 2015

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Multiple Sclerosis, Multiple Sclerosis: Relapsing-Remitting

Therapeutic Actions : Exercise

Additional Keywords : Significant Treatment Outcome

[+]

EGCG supplementation may be improved blood pressure, lipid profile, AIP, and oxidative status in patients with T2DM.Dec 24, 2020

Click here to read the entire abstract

Pubmed Data : J Complement Integr Med. 2020 Dec 25 ;18(2):405-411. Epub 2020 Dec 25. PMID: 34187117

Article Published Date : Dec 24, 2020

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Diabetes Mellitus: Type 2, Hypertension

Pharmacological Actions : Antihypertensive Agents, Antioxidants, Hypolipidemic

[+]

Epigallocatechin gallate could potentially be used as a supplement of traditional rt-PA treatment among stroke patients.Dec 08, 2016

Click here to read the entire abstract

Pubmed Data : Clin Neuropharmacol. 2016 Dec 9. Epub 2016 Dec 9. PMID: 27941526

Article Published Date : Dec 08, 2016

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Brain Ischemia, Stroke: Attenuation/Recovery

Pharmacological Actions : Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Neuroprotective Agents

[+]

Epigallocatechin gallate decreases plasma triglyceride, blood pressure, and serum kisspeptin in obese human subjects.Jan 11, 2020

Click here to read the entire abstract

Pubmed Data : Exp Biol Med (Maywood). 2020 10 12:1535370220962708. Epub 2020 Oct 12. PMID: 33045853

Article Published Date : Jan 11, 2020

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Obesity

Pharmacological Actions : Antihypertensive Agents, Hypolipidemic

[+]

Epigallocatechin gallate enhances treatment efficacy of oral nifedipine against pregnancy-induced severe pre-eclampsia.Jan 31, 2018

Click here to read the entire abstract

Pubmed Data : J Clin Pharm Ther. 2018 Feb ;43(1):21-25. Epub 2017 Jul 20. PMID: 28726273

Article Published Date : Jan 31, 2018

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Hypertension, Pre-Eclampsia

Pharmacological Actions : Antihypertensive Agents

[+]

Epigallocatechin-3-gallate mouthwash protects mucosa from radiation-induced mucositis in head and neck cancer patients.Dec 31, 2019

Click here to read the entire abstract

Pubmed Data : Invest New Drugs. 2020 08 ;38(4):1129-1136. Epub 2019 Nov 7. PMID: 31701429

Article Published Date : Dec 31, 2019

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Head and Neck Cancer, Radiation Induced Illness: Mucositis

Pharmacological Actions : Radioprotective

[+]

Green tea catechins are effective in reducing atherosclerosis risk associated with oxidative stress.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr Res. 2016 Jan ;36(1):16-23. Epub 2015 Nov 3. PMID: 26773777

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Catechin , EGCG (Epigallocatechin gallate), Green Tea

Diseases : Atherosclerosis, Lipid Peroxidation

Pharmacological Actions : Antioxidants, Cardioprotective

Additional Keywords : Risk Reduction

[+]

Green tea catechins may have a therapeutic role in the treatment of metabolic syndrome. Jan 01, 2009

Click here to read the entire abstract

Pubmed Data : Phytochemistry. 2009 Jan;70(1):11-24. Epub 2009 Jan 13. PMID: 19147161

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Metabolic Syndrome X

[+]

Green tea polyphenon E and erlotinib combination was well tolerated in patients with APLs of the head and neck.Jan 14, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Cancer Res. 2020 11 15 ;26(22):5860-5868. Epub 2020 Sep 17. PMID: 32943457

Article Published Date : Jan 14, 2020

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Head and Neck Cancer

Pharmacological Actions : Chemopreventive

[+]

High-dose green tea extract resulted in significant weight loss, reduced waist circumference, and a consistent decrease in total cholesterol and LDL plasma levels.May 28, 2015

Click here to read the entire abstract

Pubmed Data : Clin Nutr. 2015 May 29. Epub 2015 May 29. PMID: 26093535

Article Published Date : May 28, 2015

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Cholesterol: High, Obesity

Pharmacological Actions : Anticholesteremic Agents

Additional Keywords : Anti-Obesity Agents, Significant Treatment Outcome

[+]

Improvements in gait and balance in patients with multiple sclerosis after treatment with coconut oil and epigallocatechin gallate.Jan 22, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Food Funct. 2023 Jan 23 ;14(2):1062-1071. Epub 2023 Jan 23. PMID: 36594273

Article Published Date : Jan 22, 2023

Study Type : Human Study

Additional Links

Substances : Coconut Oil, EGCG (Epigallocatechin gallate)

Diseases : Multiple Sclerosis

[+]

It appears that EGCG should be taken without food in order to maximise its systemic absorption.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxidants (Basel). 2015 ;4(2):373-93. Epub 2015 May 27. PMID: 26783711

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Additional Keywords : Bioavailability

[+]

Phase II trial of epigallocatechin-3-gallate in acute radiation-induced esophagitis for esophagus cancer.Dec 31, 2019

Click here to read the entire abstract

Pubmed Data : J Med Food. 2020 Jan ;23(1):43-49. Epub 2019 Nov 20. PMID: 31747326

Article Published Date : Dec 31, 2019

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Esophageal Cancer, Radiation

Pharmacological Actions : Radioprotective

[+]

Supplementation with green tea extract significantly reduced circulating triglycerides and LDL-cholesterol concentrations.Nov 01, 2016

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2016 Nov 2. Epub 2016 Aug 2. PMID: 27806972

Article Published Date : Nov 01, 2016

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Cardiovascular Disease: Prevention, Triglycerides: Elevated

Pharmacological Actions : Anticholesteremic Agents, Hypolipidemic

Additional Keywords : Natural Substance/Drug Antagonism, Plant Extracts

Problem Substances : Statin Drugs

[+]

Tea polyphenol has potential to be a therapeutic adjuvant against human metastatic breast cancer.Feb 01, 2012

Click here to read the entire abstract

Pubmed Data : Curr Mol Med. 2012 Feb 1 ;12(2):163-76. PMID: 22280355

Article Published Date : Feb 01, 2012

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Breast Cancer, Breast Cancer: Metastatic

Pharmacological Actions : Anti-metastatic, Radiosensitizer

Additional Keywords : Drug Synergy

[+]

Tea polyphenols (primarily EGCG), significantly reduce PSA, Hepatocyte growth factor, VEG in men with prostate cancer. Jul 01, 2009

Click here to read the entire abstract

Pubmed Data : Cancer Prev Res (Phila Pa). 2009 Jul;2(7):673-82. Epub 2009 Jun 19. PMID: 19542190

Article Published Date : Jul 01, 2009

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea, Polyphenols

Diseases : Prostate: PSA Doubling, Prostate Cancer

Pharmacological Actions : Hepatocyte growth factor (HGF) inhibitor, Vascular Endothelial Growth Factor Regulator

[+]

The administration of EGCG and coconut oil seems to decrease blood triglyceride levels.Oct 10, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Foods. 2023 Oct 11 ;12(20). Epub 2023 Oct 11. PMID: 37893623

Article Published Date : Oct 10, 2023

Study Type : Human Study

Additional Links

Substances : Coconut Oil, EGCG (Epigallocatechin gallate)

Diseases : Multiple Sclerosis

Pharmacological Actions : Hypolipidemic

[+]

The association between green and black tea consumption on successful aging.May 14, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2019 May 15 ;24(10). Epub 2019 May 15. PMID: 31096548

Article Published Date : May 14, 2019

Study Type : Human Study

Additional Links

Substances : Black Tea, Coffee, EGCG (Epigallocatechin gallate), Green Tea

Diseases : Aging

[+]

The effect of (-)-epigallocatechin gallate as an adjunct to non-surgical periodontal treatment.May 02, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Trials. 2022 May 3 ;23(1):368. Epub 2022 May 3. PMID: 35505441

Article Published Date : May 02, 2022

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Periodontal Diseases

[+]

The inhalation of tea catechin appears to suppress MRSA infection in the elderly. Feb 01, 2006

Click here to read the entire abstract

Pubmed Data : J Am Med Dir Assoc. 2006 Feb;7(2):79-83. Epub 2005 Jul 22. PMID: 16461248

Article Published Date : Feb 01, 2006

Study Type : Human Study

Additional Links

Substances : Catechin , EGCG (Epigallocatechin gallate)

Diseases : Elderly: Age Specific Diseases, MRSA, Staphylococcus aureus: Methicillin-resistant (MRSA)

Pharmacological Actions : Anti-Bacterial Agents

[+]

Topical EGCG may be an effective treatment for radiation-induced dermatitis and has acceptable toxicity.May 19, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2016 May 20. Epub 2016 May 20. PMID: 27224910

Article Published Date : May 19, 2016

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Chemotherapy and Radiation Toxicity

Pharmacological Actions : Radioprotective

[+]

Topical epigallocatechin-3-gallate in the treatment of vitiligo.Jul 31, 2021

Click here to read the entire abstract

Pubmed Data : Australas J Dermatol. 2021 Aug ;62(3):e404-e407. Epub 2021 May 28. PMID: 34046892

Article Published Date : Jul 31, 2021

Study Type : Human Study

Additional Links

Substances : Catechin , EGCG (Epigallocatechin gallate)

Diseases : Vitiligo

Pharmacological Actions : Dermatologic Agents

[+]

Topical green tea extract appears safe and effective in treating external anogenital warts. Jan 01, 2006

Click here to read the entire abstract

Pubmed Data : Arterioscler Thromb Vasc Biol. 2006 Jan;26(1):85-90. Epub 2005 Oct 20. PMID: 21294779

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Anogenital Warts, Genital Warts

[+]

Twelve weeks of EGCG and resveratrol supplementation increased mitochondrial capacity and stimulated fat oxidation.May 17, 2016

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2016 May 18. Epub 2016 May 18. PMID: 27194304

Article Published Date : May 17, 2016

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Resveratrol

Diseases : Obesity

Additional Keywords : Anti-Obesity Agents

[+]

Usage of and attitudes about green tea extract and epigallocathechin-3-gallate as a therapy in individuals with Down syndrome.Jul 31, 2019

Click here to read the entire abstract

Pubmed Data : Complement Ther Med. 2019 Aug ;45:234-241. Epub 2019 Jul 2. PMID: 31331567

Article Published Date : Jul 31, 2019

Study Type : Human Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Down Syndrome

[+]

Combinations of EGCG and anticancer compounds induced synergistic anticancer effects in vitro and in vivo experiments, and showed an average reduction in tumor volume by 70.3 %.Aug 31, 2015

Click here to read the entire abstract

Pubmed Data : J Cancer Res Clin Oncol. 2015 Sep ;141(9):1511-22. Epub 2014 Dec 28. PMID: 25544670

Article Published Date : Aug 31, 2015

Study Type : Animal Study, Human In Vitro

Additional Links

Substances : Catechin , EGCG (Epigallocatechin gallate), Green Tea

Diseases : Cancers: All

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Cancer Stem Cells, Natural Substance/Drug Synergy

[+]

EGCG protected against the effects of Dihydrotestosterone (DHT) by altering the miRNA expression profile in human dermal papilla cells.May 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ann Dermatol. 2016 Jun ;28(3):327-34. Epub 2016 May 25. PMID: 27274631

Article Published Date : May 31, 2016

Study Type : Human In Vitro

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Alopecia, Hair Loss

Pharmacological Actions : Anti-Apoptotic, MicroRNA modulator

[+]

Epigallocatechin gallate suppresses Chlamydia pneumoniae mediated IgE responses.Jun 15, 2016

Click here to read the entire abstract

Pubmed Data : Minerva Med. 2016 Jun 16. Epub 2016 Jun 16. PMID: 27309037

Article Published Date : Jun 15, 2016

Study Type : Human In Vitro

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Chlamydia pneumoniae

Pharmacological Actions : Immunomodulatory

[+]

Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome.Jan 01, 2013

Click here to read the entire abstract

Pubmed Data : Biochim Biophys Acta. 2013 Jan 2. Epub 2013 Jan 2. PMID: 23291000

Article Published Date : Jan 01, 2013

Study Type : Human In Vitro

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Down Syndrome

Additional Keywords : Mitochondrial Biogenesis

[+]

Panaxadiol and Epigallocatechin Gallate have a synergistic apoptotic effect on human colorectal cancer cells.May 08, 2012

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2012 May 8. Epub 2012 May 8. PMID: 22566066

Article Published Date : May 08, 2012

Study Type : Human In Vitro

Additional Links

Substances : Catechin , EGCG (Epigallocatechin gallate), Ginseng, Green Tea, Panaxadiol

Diseases : Colorectal Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer

Additional Keywords : Natural Substance Synergy

[+]

Punicalagin and EGCG can rescue keratinocyte viability and attenuate the inflammatory responses of cells due to airborne particles.Mar 21, 2018

Click here to read the entire abstract

Pubmed Data : Skin Pharmacol Physiol. 2018 Mar 22 ;31(3):134-143. Epub 2018 Mar 22. PMID: 29566388

Article Published Date : Mar 21, 2018

Study Type : Human In Vitro

Additional Links

Substances : EGCG (Epigallocatechin gallate), Punicalagin

Diseases : Air Pollution Linked Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

These results provide new evidence for the effectiveness of EGCG in vitiligo treatment.Sep 03, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biol Pharm Bull. 2015 Sep 4. Epub 2015 Sep 4. PMID: 26345342

Article Published Date : Sep 03, 2015

Study Type : Human In Vitro

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Vitiligo

Pharmacological Actions : Anti-Inflammatory Agents

[+]

VEGF is a key molecular target for specific polyphenols found in tea, apples and cocoa which potently inhibit VEGF signalling and angiogenesis at physiological concentrations.Feb 28, 2015

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2015 Mar ;59(3):401-12. Epub 2015 Jan 22. PMID: 25546248

Article Published Date : Feb 28, 2015

Study Type : Human In Vitro

Additional Links

Substances : Apple Polyphenols, EGCG (Epigallocatechin gallate), Polyphenols

Diseases : Cancers: All

Pharmacological Actions : Angiogenesis Inhibitors, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Diet

[+]

A case of complete and durable molecular remission of chronic lymphocytic leukemia following treatment with epigallocatechin-3-gallate.Dec 31, 2014

Click here to read the entire abstract

Pubmed Data : Cureus. 2015 ;7(12):e441. Epub 2015 Dec 29. PMID: 26858922

Article Published Date : Dec 31, 2014

Study Type : Human: Case Report

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Chronic Lymphocytic Leukemia

Pharmacological Actions : Chemopreventive

Additional Keywords : Cancer Remission, Significant Treatment Outcome

[+]

Co-delivery of EGCG and melittin with self-assembled fluoro-nanoparticles for enhanced cancer therapy.Jun 04, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Aging (Albany NY). 2023 Jun 5 ;15(11):4875-4888. Epub 2023 Jun 5. PMID: 37277118

Article Published Date : Jun 04, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Bee Venom, EGCG (Epigallocatechin gallate)

Diseases : Cancers: All

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

EGCG disrupts the LIN28B/Let-7 interaction and reduces neuroblastoma aggressiveness.Apr 26, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2024 Apr 27 ;25(9). Epub 2024 Apr 27. PMID: 38732012

Article Published Date : Apr 26, 2024

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Neuroblastoma

Pharmacological Actions : Antiproliferative

[+]

Epicatechin gallate blocked cellular foam formation in atherosclerosis.Mar 05, 2023

Click here to read the entire abstract

Pubmed Data : Food Funct. 2023 Mar 6 ;14(5):2444-2458. Epub 2023 Mar 6. PMID: 36786689

Article Published Date : Mar 05, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Atherosclerosis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, NF-kappaB Inhibitor, Nrf2 activation

[+]

Epigallocatechin-3-gallate improves the quality of maternally aged oocytes.Nov 26, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cell Prolif. 2023 Nov 27:e13575. Epub 2023 Nov 27. PMID: 38010042

Article Published Date : Nov 26, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Infertility: Female

Pharmacological Actions : Fertility Agents: Female

[+]

Synergetic EGCG and coenzyme Q10 DSPC liposome nanoparticles protect against myocardial infarction.Oct 09, 2023

Click here to read the entire abstract

Pubmed Data : Biomater Sci. 2023 Oct 10 ;11(20):6862-6870. Epub 2023 Oct 10. PMID: 37646313

Article Published Date : Oct 09, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Coenzyme Q10, EGCG (Epigallocatechin gallate)

Diseases : Myocardial Infarction

Pharmacological Actions : Anti-Apoptotic, Cardioprotective

Additional Keywords : Natural Substance Synergy

[+]

The anti-cancer effect of epigallocatechin-3-O-gallate against multiple myeloma cells is potentiated by 5,7-dimethoxyflavone.Oct 31, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : FEBS Open Bio. 2023 Nov ;13(11):2147-2156. Epub 2023 Sep 25. PMID: 37730921

Article Published Date : Oct 31, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Multiple Myeloma

Pharmacological Actions : Apoptotic

[+]

Epigallocatechin gallate but not catechin prevents nonalcoholic steatohepatitis in mice similar to green tea extract while differentially affecting the gut microbiota.Jun 19, 2020

Click here to read the entire abstract

Pubmed Data : J Nutr Biochem. 2020 Jun 20 ;84:108455. Epub 2020 Jun 20. PMID: 32688217

Article Published Date : Jun 19, 2020

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective

[+]

Sex-specific oxidative damage effects induced by BPA and its analogs on primary hippocampal neurons attenuated by EGCG.Sep 27, 2020

Click here to read the entire abstract

Pubmed Data : Chemosphere. 2020 Sep 28 ;264(Pt 1):128450. Epub 2020 Sep 28. PMID: 33007573

Article Published Date : Sep 27, 2020

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Bisphenol Toxicity

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Neurotoxic

[+]

Synergistic Effect of β-cryptoxanthin and epigallocatechin gallate on obesity reduction. Jul 19, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2024 Jul 20 ;16(14). Epub 2024 Jul 20. PMID: 39064787

Article Published Date : Jul 19, 2024

Study Type : Animal Study

Additional Links

Substances : Cryptoxanthin, EGCG (Epigallocatechin gallate)

Diseases : Obesity

Pharmacological Actions : Hepatoprotective

Additional Keywords : Anti-Obesity Agents, Natural Substance Synergy

[+]

The green tea polyphenol epigallocatechin-3-gallate attenuates age-associated muscle loss via regulation of miR-486-5p and myostatin.Jul 21, 2020

Click here to read the entire abstract

Pubmed Data : Arch Biochem Biophys. 2020 Jul 22 ;692:108511. Epub 2020 Jul 22. PMID: 32710883

Article Published Date : Jul 21, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Muscle Atrophy

Pharmacological Actions : MicroRNA modulator

[+]

"Amelioration of influenza virus-induced reactive oxygen species formation by epigallocatechin gallate derived from green tea."Nov 30, 2012

Click here to read the entire abstract

Pubmed Data : Acta Pharmacol Sin. 2012 Dec ;33(12):1533-41. Epub 2012 Sep 3. PMID: 22941291

Article Published Date : Nov 30, 2012

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Influenza A

[+]

"Green tea catechins ameliorates adipose Insulin resistance by improving oxidative stress."Feb 11, 2012

Click here to read the entire abstract

Pubmed Data : Free Radic Biol Med. 2012 Feb 11. Epub 2012 Feb 11. PMID: 22330066

Article Published Date : Feb 11, 2012

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Insulin Resistance

Pharmacological Actions : Antioxidants

[+]

"Green tea epigallocatechin-3-gallate (EGCG) promotes neural progenitor cell proliferation and sonic hedgehog pathway activation during adult hippocampal neurogenesis."Jul 31, 2012

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2012 Aug ;56(8):1292-303. Epub 2012 Jun 13. PMID: 22692966

Article Published Date : Jul 31, 2012

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Brain Injury: Hippocampal Damage

Pharmacological Actions : Neuritogenic

[+]

"Green tea epigallocatechin-3-gallate attenuates Porphyromonas gingivalis-induced atherosclerosis."Sep 10, 2012

Click here to read the entire abstract

Pubmed Data : FEMS Immunol Med Microbiol. 2012 Sep 11. Epub 2012 Sep 11. PMID: 22966806

Article Published Date : Sep 10, 2012

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Atherosclerosis, Porphyromonas gingivalis

Pharmacological Actions : Cardioprotective

[+]

(-)-Epigallocatechin-3-gallate (EGCG) can inhibit the proliferation and invasiveness and induce apoptosis in nasopharyngeal carcinoma cells.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2015 ;16(2):2530-58. Epub 2015 Jan 23. PMID: 25625511

Article Published Date : Dec 31, 2014

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Nasopharyngeal Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic

[+]

A combination of nutrients improves cognitive functioning while decreasing Alzheimer disease neuropathology in an animal model.Jan 01, 2010

Click here to read the entire abstract

Pubmed Data : PLoS One. 2010;5(11):e14015. Epub 2010 Nov 17. PMID: 21103342

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Substances : Alpha-Lipoic Acid, B-complex, Curcumin, EGCG (Epigallocatechin gallate), Folic Acid , NAC (N-acetyl-L-cysteine), Piperine, Vitamin C

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

A major metabolite of EGCG increased the activity of CD4(+) T cells and enhanced the cytotoxic activity of NK cells in vivo.May 10, 2016

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Pubmed Data : J Agric Food Chem. 2016 May 11 ;64(18):3591-7. Epub 2016 May 2. PMID: 27112424

Article Published Date : May 10, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Pharmacological Actions : Immunostimulatory

Additional Keywords : Metabolites

[+]

A quercetin, EGCG and apple polyphenol concentrate improved disorders of lipid metabolism and pro-oxidant-antioxidant homeostasis.Dec 31, 2016

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Pubmed Data : Wiad Lek. 2017;70(2):200-204. PMID: 28511159

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Apple Polyphenols, Catechin , EGCG (Epigallocatechin gallate), Quercetin

Diseases : Insulin Resistance

Pharmacological Actions : Antioxidants

Additional Keywords : Natural Substance Synergy, Plant Extracts

[+]

Administration of Epigallocatechin-3-gallate resulted in a significant reduction in bone loss.Sep 06, 2015

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Pubmed Data : Int Immunopharmacol. 2015 Sep 7. Epub 2015 Sep 7. PMID: 26359545

Article Published Date : Sep 06, 2015

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Gingivitis, Periodontitis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

All these findings suggest that EGCG can resist skin senility effectively.Mar 22, 2017

Click here to read the entire abstract

Pubmed Data : Mech Ageing Dev. 2017 Mar 23. Epub 2017 Mar 23. PMID: 28343910

Article Published Date : Mar 22, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Aging Skin, Oxidative Stress

Pharmacological Actions : Antioxidants

[+]

Alleviation effects of epigallocatechin-3-gallate against acute kidney injury following severe burns.Oct 16, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Exp Nephrol. 2023 Oct 17. Epub 2023 Oct 17. PMID: 37847436

Article Published Date : Oct 16, 2023

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Burns, Kidney Damage

Pharmacological Actions : Renoprotective

[+]

Anti-alzheimer activity of combinations of cocoa with vinpocetine or other nutraceuticals.Jul 30, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pharmaceutics. 2023 Jul 31 ;15(8). Epub 2023 Jul 31. PMID: 37631278

Article Published Date : Jul 30, 2023

Study Type : Animal Study

Additional Links

Substances : Cocoa, Coenzyme Q10, EGCG (Epigallocatechin gallate), Vinpocetine

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Anti-angiogenic effects of green tea catechin on an experimental endometriosis model.Feb 28, 2009

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Hum Reprod. 2009 Mar ;24(3):608-18. Epub 2008 Dec 16. PMID: 19088106

Article Published Date : Feb 28, 2009

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Endometriosis

Pharmacological Actions : Anti-Angiogenic, Antiproliferative

[+]

Antimicrobial effect of Licochalcone A and Epigallocatechin-3-gallate against Salmonella Typhimurium isolated from poultry flocks.Jan 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Microbiol. 2018 Feb ;10(1):51-58. PMID: 29922419

Article Published Date : Jan 31, 2018

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Licorice

Diseases : Salmonella Infections

Pharmacological Actions : Antimicrobial

[+]

Antitumor effect of epigallocatechin gallate and vincristine in mice with L5178Y lymphoma.Nov 01, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Plants (Basel). 2023 Nov 2 ;12(21). Epub 2023 Nov 2. PMID: 37960113

Article Published Date : Nov 01, 2023

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Lymphoma

Pharmacological Actions : Bcl-2 protein down-regulation, Chemopreventive, Chemosensitizer

Additional Keywords : Natural Substance/Drug Synergy

[+]

Artificial tears containing epigallocatechin gallate and hyaluronic acid had a synergistic effect in the treatment of dry eye syndrome.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2016;11(6):e0157982. Epub 2016 Jun 23. PMID: 27336157

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Dry Eye Syndromes

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Natural Substance Synergy

[+]

Attenuation of methotrexate induced hepatotoxicity by epigallocatechin 3-gallate.Jun 13, 2022

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Pubmed Data : Drug Chem Toxicol. 2022 Jun 14:1-9. Epub 2022 Jun 14. PMID: 35698845

Article Published Date : Jun 13, 2022

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Chemically-Induced Liver Damage, Drug Toxicity: Methotrexate

Pharmacological Actions : Hepatoprotective

Problem Substances : Methotrexate

[+]

Beneficial impact of epigallocatechingallate on LDL-C through PCSK9/LDLR pathway by blocking HNF1α and activating FoxO3a.May 11, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Transl Med. 2020 May 12 ;18(1):195. Epub 2020 May 12. PMID: 32398139

Article Published Date : May 11, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cardiovascular Diseases

Pharmacological Actions : Anticholesteremic Agents, Cardioprotective, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

[+]

Caffeine and EGCG alleviate high-trans fatty acid and high-carbohydrate diet-induced NASH.Dec 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Nutr. 2021 ;8:784354. Epub 2021 Nov 22. PMID: 34881283

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Caffeine, EGCG (Epigallocatechin gallate)

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

Catechin and EGCG could repair liver injury and regulate lipid metabolism of hepatocytes in alcoholic fatty liver disease mice models.Nov 05, 2021

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Pubmed Data : Zhonghua Yu Fang Yi Xue Za Zhi. 2021 Nov 6 ;55(11):1305-1310. PMID: 34749473

Article Published Date : Nov 05, 2021

Study Type : Animal Study

Additional Links

Substances : Catechin , EGCG (Epigallocatechin gallate)

Diseases : Alcoholic Liver Disease

Pharmacological Actions : Hepatoprotective

[+]

Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging.Mar 19, 2023

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Pubmed Data : Food Funct. 2023 Mar 20 ;14(6):2684-2697. Epub 2023 Mar 20. PMID: 36752162

Article Published Date : Mar 19, 2023

Study Type : Animal Study

Additional Links

Substances : Chlorogenic Acid, EGCG (Epigallocatechin gallate)

Diseases : Aging

Pharmacological Actions : Antioxidants

[+]

Chronic treatment of diabetic rats with EGCG could prevent the abnormal functional changes in vascular reactivity in diabetic rats.Dec 01, 1975

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Pubmed Data : Am J Med Technol. 1975 Dec;41(12):457-62. PMID: 2010

Article Published Date : Dec 01, 1975

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Diabetes: Cardiovascular Illness

Pharmacological Actions : Cardioprotective

[+]

Co-administration of EGCG and doxorubicin has potential as a feasible strategy to mitigate the drugs cardiotoxicity.Dec 08, 2016

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Pubmed Data : Life Sci. 2016 Dec 9. Epub 2016 Dec 9. PMID: 27956351

Article Published Date : Dec 08, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Antiproliferative , Apoptotic, Cardioprotective, Chemoprotective Agents

Additional Keywords : Chemotherapeutic Synergy: Doxorubicin

[+]

Coadministration of epigallocatechin-3-gallate and caffeine in low dose ameliorates obesity and nonalcoholic fatty liver disease in obese rats.Feb 10, 2019

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Pubmed Data : Phytother Res. 2019 Feb 11. Epub 2019 Feb 11. PMID: 30746789

Article Published Date : Feb 10, 2019

Study Type : Animal Study

Additional Links

Substances : Caffeine, EGCG (Epigallocatechin gallate)

Diseases : Nonalcoholic fatty liver disease (NAFLD), Obesity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Anti-Obesity Agents

[+]

Combined treatment with the phenolics (-)-epigallocatechin-3-gallate and ferulic acid improves cognition and reduces Alzheimer-like pathology.Jan 21, 2019

Click here to read the entire abstract

Pubmed Data : J Biol Chem. 2019 02 22 ;294(8):2714-2731. Epub 2018 Dec 18. PMID: 30563837

Article Published Date : Jan 21, 2019

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Ferulic acid

Diseases : Alzheimer's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

[+]

Consumption of green tea may be beneficial in alleviating some of the deleterious aspects of aging and immunosenescence in elderly.Mar 23, 2017

Click here to read the entire abstract

Pubmed Data : Biogerontology. 2017 Mar 24. Epub 2017 Mar 24. PMID: 28341876

Article Published Date : Mar 23, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Aging

Pharmacological Actions : Antioxidants, Immunomodulatory, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Curcumin as a permeability enhancer enhanced the antihyperlipidemic activity of dietary green tea extract.Jun 12, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Complement Altern Med. 2019 Jun 13 ;19(1):129. Epub 2019 Jun 13. PMID: 31196040

Article Published Date : Jun 12, 2019

Study Type : Animal Study

Additional Links

Substances : Catechin , Curcumin, EGCG (Epigallocatechin gallate)

Diseases : Hyperlipidemia

Pharmacological Actions : Antioxidants, Hypolipidemic

Additional Keywords : Natural Substance Synergy

[+]

Curcumin, resveratrol, and EGCG, repolarizes tumor-associated macrophages and triggers an immune response to cause suppression of HPV+ tumors.Feb 15, 2018

Click here to read the entire abstract

Pubmed Data : Cancer Immunol Immunother. 2018 Feb 16. Epub 2018 Feb 16. PMID: 29453519

Article Published Date : Feb 15, 2018

Study Type : Animal Study

Additional Links

Substances : Curcumin, EGCG (Epigallocatechin gallate), Resveratrol

Diseases : Head and Neck Cancer, Human Papillomavirus (HPV)

Pharmacological Actions : Immunomodulatory

Additional Keywords : Natural Substance Synergy

[+]

Daily consumption of EGCG might be effective in the prevention and treatment of secondary damage related to peripheral nerve injury.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Turk Neurosurg. 2015 ;25(3):453-60. PMID: 26037187

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Lipid Peroxidation, Peripheral Nerve Diseases, Sciatica

Pharmacological Actions : Antioxidants

[+]

Diallyl disulfide potentiates anti-obesity effect of green tea in high-fat/high-sucrose diet-induced obesity.Dec 31, 2018

Click here to read the entire abstract

Pubmed Data : J Nutr Biochem. 2019 02 ;64:152-161. Epub 2018 Nov 3. PMID: 30504007

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : High Fat Diet, High Sugar Diet, Obesity

Additional Keywords : Anti-Obesity Agents, Natural Substance Synergy

[+]

Diet supplementation with green tea extract epigallocatechin gallate prevents progression to glucose intolerance in mice.Feb 14, 2012

Click here to read the entire abstract

Pubmed Data : Nutr Metab (Lond). 2012 Feb 14 ;9(1):11. Epub 2012 Feb 14. PMID: 22333133

Article Published Date : Feb 14, 2012

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Diabetes Mellitus: Type 2

Additional Keywords : Beta Cell Protection

[+]

Diet supplemented with phytochemical epigallocatechin gallate and probiotic Lactobacillus fermentum confers second generation synbiotic effects.Jan 02, 2019

Click here to read the entire abstract

Pubmed Data : Eur J Nutr. 2019 Jan 3. Epub 2019 Jan 3. PMID: 30607562

Article Published Date : Jan 02, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Lactobacillus fermentum

Diseases : Aging

Pharmacological Actions : Antioxidants

[+]

Dietary supplementation of a high-temperature-processed green tea extract attenuates cognitive impairment.Aug 28, 2019

Click here to read the entire abstract

Pubmed Data : Biosci Biotechnol Biochem. 2019 Aug 29:1-8. Epub 2019 Aug 29. PMID: 31462168

Article Published Date : Aug 28, 2019

Study Type : Transgenic Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Drinking green tea may reduce the toxic potential of acute high oral doses of EGCG supplementation. Jan 31, 2015

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2015 Feb ;76:103-8. Epub 2014 Dec 17. PMID: 25528115

Article Published Date : Jan 31, 2015

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Pharmacological Actions : Hepatoprotective

Additional Keywords : Bioavailability, Natural Substance Synergy, Supplementation

[+]

ECG may be used as an anti-invasion agent for the adjuvant treatment and metastasis control of human lung cancer cells.Jul 31, 2016

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2016 Aug ;94:1-10. Epub 2016 May 17. PMID: 27224248

Article Published Date : Jul 31, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Lung Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor

Additional Keywords : Fibronectin

[+]

Effect of a cyclooxygenase-2 inhibitor in combination with (-)-epigallocatechin gallate or polyphenon E on cisplatin-induced lung tumorigenesis.Jan 31, 2023

Click here to read the entire abstract

Pubmed Data : Acta Med Okayama. 2023 Feb ;77(1):65-70. PMID: 36849147

Article Published Date : Jan 31, 2023

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Lung Cancer

Pharmacological Actions : Chemotherapeutic, Cyclooxygenase 2 Inhibitors

[+]

Effect of epigallocatechin gallate in green tea on preventing lens opacity and αB-crystallin aggregation.Dec 31, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Ophthalmol. 2023 ;16(3):342-347. Epub 2023 Mar 18. PMID: 36935798

Article Published Date : Dec 31, 2022

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Diabetes: Cataract

[+]

Effects of epigallocatechin gallate, caffeine, and their combination on fat accumulation in high-glucose diet-fed Caenorhabditis elegans.Jul 23, 2023

Click here to read the entire abstract

Pubmed Data : Biosci Biotechnol Biochem. 2023 Jul 24 ;87(8):898-906. PMID: 37363872

Article Published Date : Jul 23, 2023

Study Type : Animal Study

Additional Links

Substances : Caffeine, EGCG (Epigallocatechin gallate)

Diseases : Obesity

Additional Keywords : Anti-Obesity Agents

[+]

Effects of epigallocatechin-3-gallate on oxidative stress, inflammation, and bone loss in a rat periodontitis model.Sep 30, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Dent Sci. 2023 Oct ;18(4):1567-1575. Epub 2023 Mar 11. PMID: 37799898

Article Published Date : Sep 30, 2023

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Oxidative Stress, Periodontitis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Effects of flavonoids and Its derivatives on immune cell responses.Dec 31, 2018

Click here to read the entire abstract

Pubmed Data : Recent Pat Inflamm Allergy Drug Discov. 2019 ;13(2):84-104. PMID: 31814545

Article Published Date : Dec 31, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Apigenin, EGCG (Epigallocatechin gallate), Flavonoids, Quercetin

Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-1 beta downregulation, Interleukin-2 Downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Effects of green tea polyphenol epigallocatechin-3-gallate on markers of inflammation and fibrosis in a model of pulmonary silicosis.Jan 16, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2023 Jan 17 ;24(3). Epub 2023 Jan 17. PMID: 36768179

Article Published Date : Jan 16, 2023

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Polyphenols

Diseases : Inflammation, Silicosis

Pharmacological Actions : Anti-Apoptotic, Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants

[+]

Efficacy of epigallocatechin gallate (EGCG) and its underlying mechanism in preventing bisphenol-A-induced metabolic disorders.May 04, 2024

Click here to read the entire abstract

Pubmed Data : J Hazard Mater. 2024 May 5 ;469:134098. Epub 2024 Mar 21. PMID: 38522198

Article Published Date : May 04, 2024

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Bisphenol Toxicity, Dysbiosis, Metabolic Diseases

Pharmacological Actions : Gastrointestinal Agents

Problem Substances : Bisphenol A

[+]

EGCG administration had neurorestorative effects after bilateral common carotid artery occlusion.Apr 10, 2016

Click here to read the entire abstract

Pubmed Data : Restor Neurol Neurosci. 2016 Apr 11 ;34(3):367-77. PMID: 27080069

Article Published Date : Apr 10, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cerebral Hypoperfusion

Pharmacological Actions : Neurorestorative

[+]

EGCG alleviates obesity-exacerbated lung cancer progression.Jul 12, 2023

Click here to read the entire abstract

Pubmed Data : J Nutr Biochem. 2023 Jul 13 ;120:109416. Epub 2023 Jul 13. PMID: 37451475

Article Published Date : Jul 12, 2023

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Lung Cancer, Obesity

Pharmacological Actions : Gastrointestinal Agents

[+]

EGCG alleviates obesity-induced myocardial fibrosis.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Cardiovasc Med. 2022 ;9:869279. Epub 2022 Apr 29. PMID: 35571212

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Myocardial Fibrosis

Pharmacological Actions : Anti-Fibrotic, Cardioprotective

[+]

EGCG ameliorates lethal graft versus host disease and reduces related target organ damage.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2017 ;12(1):e0169630. Epub 2017 Jan 19. PMID: 28103249

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Graft vs Host Disease

Pharmacological Actions : Antioxidants, Immunomodulatory

Additional Keywords : Antioxidants, EGCG (Epigallocatechin gallate), Graft vs Host Disease, Hematopoietic Stem Cells, Immunomodulatory, Risk Reduction

[+]

EGCG and CoQ10 ameliorate cisplatin induced nephrotoxicity.Jun 01, 2016

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2016 Jun 2. Epub 2016 Jun 2. PMID: 27265264

Article Published Date : Jun 01, 2016

Study Type : Animal Study

Additional Links

Substances : Coenzyme Q10, EGCG (Epigallocatechin gallate)

Diseases : Chemotherapy-Induced Toxicity: Cisplatin

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents

[+]

EGCG and ellagic acid have protective effects on cataract development via the inhibition of oxidative stress.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Ophthalmol. 2017 ;10(4):499-506. Epub 2017 Apr 18. PMID: 28503419

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Ellagic Acid

Diseases : Cataract

Pharmacological Actions : Antioxidants

[+]

EGCG appears to attenuate cardiopulmonary bypass-associated lung injury.Mar 31, 2016

Click here to read the entire abstract

Pubmed Data : J Surg Res. 2016 Apr ;201(2):313-25. Epub 2015 Nov 11. PMID: 27020813

Article Published Date : Mar 31, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Coronary Bypass Surgery, Lung Injury: Acute

Additional Keywords : Risk Reduction

[+]

EGCG attenuated abdominal aortic aneurysm progression in a rat model by preserving the aortic thickness and elastin content of the medial layer.May 31, 2017

Click here to read the entire abstract

Pubmed Data : J Vasc Surg. 2017 Jun ;65(6):1803-1812.e2. Epub 2016 Jul 26. PMID: 27473778

Article Published Date : May 31, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Aneurysm: Aortic

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Matrix metalloproteinase-2 (MMP-2) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Phytotherapy, Plant Extracts

[+]

EGCG attenuates CA1 neuronal death in the rat hippocampus following status epilepticus.Apr 19, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxidants (Basel). 2023 Apr 20 ;12(4). Epub 2023 Apr 20. PMID: 37107343

Article Published Date : Apr 19, 2023

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Epilepsy

Pharmacological Actions : Neuroprotective Agents

[+]

EGCG can attenuate high-fat-induced hypothalamic inflammation.Oct 12, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2019 Oct 13 ;20(20). Epub 2019 Oct 13. PMID: 31614951

Article Published Date : Oct 12, 2019

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Brain Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

EGCG can be developed into a potential agent for the prevention and treatment of smoking‑associated NSCLC.May 31, 2015

Click here to read the entire abstract

Pubmed Data : Oncol Rep. 2015 Jun ;33(6):2972-80. Epub 2015 Mar 31. PMID: 25845434

Article Published Date : May 31, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Carcinoma: Small Cell Lung, Nicotine/Tobacco Toxicity

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Hypoxia-inducible factor-1 (HIF-1) inhibitor, Vascular Endothelial Growth Factor Inhibitors

[+]

EGCG can decrease obesity and epididymal white adipose tissue weight in mice.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2018 ;9:1366. Epub 2018 Nov 22. PMID: 30524290

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Obesity

Additional Keywords : Anti-Obesity Agents

[+]

EGCG can reduce lung injury and airway remodelling in air pollution-exposed asthmatic rats.Apr 15, 2019

Click here to read the entire abstract

Pubmed Data : Biochem Biophys Res Commun. 2019 Apr 16. Epub 2019 Apr 16. PMID: 31003767

Article Published Date : Apr 15, 2019

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Air Pollution Linked Toxicity, Asthma

Pharmacological Actions : Anti-Inflammatory Agents

[+]

EGCG consumption prevented diabetes-induced loss of cavernous smooth muscle.May 11, 2016

Click here to read the entire abstract

Pubmed Data : Int J Impot Res. 2016 May 12. Epub 2016 May 12. PMID: 27169491

Article Published Date : May 11, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Diabetes Mellitus: Type 1, Diabetic Complications, Erectile Dysfunction

[+]

EGCG could attenuate cadmium induced chronic renal injury.Jul 25, 2016

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2016 Jul 26. Epub 2016 Jul 26. PMID: 27474435

Article Published Date : Jul 25, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cadmium Poisoning , Kidney Damage: Chemically-Induced

Pharmacological Actions : MicroRNA modulator, Renoprotective

[+]

EGCG could attenuate Sodium arsenite-induced cardiotoxicity.May 07, 2016

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2016 May 8. Epub 2016 May 8. PMID: 27170490

Article Published Date : May 07, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Arsenic Poisoning

Pharmacological Actions : Cardioprotective

Problem Substances : Arsenite

[+]

EGCG could attenuate testosterone-induced benign prostatic hyperplasia and fibrosis.Aug 31, 2018

Click here to read the entire abstract

Pubmed Data : Int Immunopharmacol. 2018 Sep 1 ;64:162-169. Epub 2018 Sep 1. PMID: 30179845

Article Published Date : Aug 31, 2018

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Prostatic Hyperplasia: Benign

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

[+]

EGCG could be coadministered with rt-PA, to extend its therapeutic window in treating acute brain ischemia.Mar 31, 2016

Click here to read the entire abstract

Pubmed Data : J Stroke Cerebrovasc Dis. 2016 Apr ;25(4):990-7. Epub 2016 Feb 3. PMID: 26851971

Article Published Date : Mar 31, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Brain Ischemia, Stroke: Attenuation/Recovery

Pharmacological Actions : Neuroprotective Agents

[+]

EGCG could be used in the prevention or in the therapy of anthrax infections. Mar 31, 2004

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : EMBO Rep. 2004 Apr ;5(4):418-22. Epub 2004 Mar 12. PMID: 15031715

Article Published Date : Mar 31, 2004

Study Type : Animal Study

Additional Links

Substances : Catechin , EGCG (Epigallocatechin gallate), Green Tea

Diseases : Anthrax

Pharmacological Actions : Anti-Apoptotic, Matrix Metalloproteinases Inhibitors

Additional Keywords : Anthrax Lethal Factor

[+]

EGCG could be useful for the prevention and treatment of rheumatoid arthritis and other inflammatory disorders.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Inflamm (Lond). 2015 ;12:53. Epub 2015 Sep 15. PMID: 26379475

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Rheumatoid Arthritis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Immunomodulatory, NF-E2-Related Factor-2 (Nrf2) Modulator

[+]

EGCG could have beneficial effects on neurogenesis and stroke recovery. May 19, 2016

Click here to read the entire abstract

Pubmed Data : Mol Neurobiol. 2016 May 20. Epub 2016 May 20. PMID: 27206430

Article Published Date : May 19, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Stroke: Attenuation/Recovery

Pharmacological Actions : Neurogenesis

[+]

EGCG could mitigate the teratogenic effects of hyperglycemia on the developing embryo and prevent diabetes-induced neural tube defects.Mar 11, 2016

Click here to read the entire abstract

Pubmed Data : Am J Obstet Gynecol. 2016 Mar 12. Epub 2016 Mar 12. PMID: 26979632

Article Published Date : Mar 11, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Gestational Diabetes, Hyperglycemia, Neural Tube Defects

Additional Keywords : Hypomethylation, Methylation Downregulation, Risk Reduction

[+]

EGCG could potentially serve as an additional therapeutic intervention in the arsenal against obesity.Feb 08, 2018

Click here to read the entire abstract

Pubmed Data : Food Funct. 2018 Feb 9. Epub 2018 Feb 9. PMID: 29423494

Article Published Date : Feb 08, 2018

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : High Fat Diet, Insulin Resistance, Obesity, Oxidative Stress

Pharmacological Actions : Antioxidants, Nrf2 activation

Additional Keywords : Anti-Obesity Agents

[+]

EGCG could restore unilateral ureteral obstruction induced kidney weight loss and renal dysfunction in a mice model.Jan 26, 2015

Click here to read the entire abstract

Pubmed Data : Basic Clin Pharmacol Toxicol. 2015 Jan 27. Epub 2015 Jan 27. PMID: 25625183

Article Published Date : Jan 26, 2015

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Obstructive Nephropathy, Oxidative Stress

Pharmacological Actions : Antioxidants, Nrf2 activation, Renoprotective

Additional Keywords : Disease Reversal

[+]

EGCG decreased the arthritis index and showed protective effects against joint destruction in collagen-induced arthritis mice.Mar 07, 2016

Click here to read the entire abstract

Pubmed Data : J Leukoc Biol. 2016 Mar 8. Epub 2016 Mar 8. PMID: 26957211

Article Published Date : Mar 07, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Rheumatoid Arthritis

Pharmacological Actions : Heme oxygenase-1 up-regulation, Immunomodulatory: Th17 downregulation, NF-E2-Related Factor-2 (Nrf2) Modulator, STAT3 Inhibitor

[+]

EGCG decreases colonic inflammation and permeability in a mouse model of colitis, but reduces macronutrient digestion.May 23, 2016

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2016 May 24. Epub 2016 May 24. PMID: 27218415

Article Published Date : May 23, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Colitis, Gastrointestinal Inflammation, Inflammatory Bowel Diseases

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Macronutrient

[+]

EGCG decreases ovariectomy-induced bone loss via inhibition of osteoclasts.Mar 21, 2012

Click here to read the entire abstract

Pubmed Data : Calcif Tissue Int. 2012 Mar 21. Epub 2012 Mar 21. PMID: 22434366

Article Published Date : Mar 21, 2012

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Osteoporosis

Additional Keywords : Ovariectomy-Induced Changes

[+]

EGCG dose-dependently improves insulin resistance in NAFLD miceApr 30, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Acta Pharmacol Sin. 2015 May ;36(5):597-605. Epub 2015 Apr 20. PMID: 25891086

Article Published Date : Apr 30, 2015

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Hyperlipidemia, Hypoglycemia, Insulin Resistance

Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic

Additional Keywords : Phytotherapy

[+]

EGCG enhanced the anti-tumor effect of doxorubicine in bladder cancer.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Cell Dev Biol. 2020 ;8:606123. Epub 2020 Dec 23. PMID: 33425912

Article Published Date : Dec 31, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Bladder Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Chemosensitizer, P21 Activation, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Chemotherapeutic Synergy: Doxorubicin

[+]

EGCG enhances 5FU sensitivity in chemoresistant colorectal cancer by targeting cancer stem cells.Mar 28, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2016 Mar 29 ;7(13):16158-71. PMID: 26930714

Article Published Date : Mar 28, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cancers: Drug Resistant, Colorectal Cancer

Pharmacological Actions : Antiproliferative , Chemosensitizer, MicroRNA modulator

Additional Keywords : Cancer Stem Cells, Chemothapeutic Synergy: 5-flourouracil

[+]

EGCG exerts a neuroprotective effect on experimental autoimmune thyroiditis.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2018 Jan ;15(1):1087-1092. Epub 2017 Nov 14. PMID: 29434699

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Autoimmune Thyroiditis, Thyroiditis: Autoimmune

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents

[+]

EGCG exerts anti-inflammatory effect against monosodium urate induced acute gout attack.May 27, 2016

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2016 May 28. Epub 2016 May 28. PMID: 27234527

Article Published Date : May 27, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Gout

Pharmacological Actions : Anti-Inflammatory Agents

[+]

EGCG exhibits anti-fibrotic effects in a rat model of pulmonary fibrosis. Jul 15, 2009

Click here to read the entire abstract

Pubmed Data : Chem Biol Interact. 2009 Jul 15;180(2):271-80. Epub 2009 Mar 20. PMID: 19497426

Article Published Date : Jul 15, 2009

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis

[+]

EGCG from gestation to adulthood suppressed 3R-tau expression and rescued anxiety and memory deficits in Ts65Dn mouse brains.Apr 03, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2017 Apr 4 ;7(1):619. Epub 2017 Apr 4. PMID: 28377597

Article Published Date : Apr 03, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Down Syndrome

Pharmacological Actions : Neuroprotective Agents

[+]

EGCG has a beneficial effect on impaired adult neurogenesis caused by lipopolysaccharide induced neuro-inflammation.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Korean J Physiol Pharmacol. 2016 Jan ;20(1):41-51. Epub 2015 Dec 31. PMID: 26807022

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

[+]

EGCG has a protective effect on rat brain injury induced by middle cerebral artery occlusion.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2018 ;2018:6473580. Epub 2018 Mar 25. PMID: 29770336

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Middle Cerebral Artery Occlusion (MCAO)

Pharmacological Actions : Neuroprotective Agents

[+]

EGCG has an antiarthritic effect by regulating the oxidative-antioxidant balance and cytokine levels.Nov 18, 2019

Click here to read the entire abstract

Pubmed Data : Biotechnol Appl Biochem. 2019 Nov 19. Epub 2019 Nov 19. PMID: 31746064

Article Published Date : Nov 18, 2019

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Arthritis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Immunomodulatory: Th17 downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

EGCG has multifunctional therapeutic effects in the mouse model of ALSOct 01, 2006

Click here to read the entire abstract

Pubmed Data : Neurochem Res. 2006 Oct;31(10):1263-9. Epub 2006 Oct 5. PMID: 17021948

Article Published Date : Oct 01, 2006

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Amyotrophic Lateral Sclerosis

[+]

EGCG has significant antipathogenic effects on C. difficile.Nov 30, 2015

Click here to read the entire abstract

Pubmed Data : J Food Sci. 2015 Dec ;80(12):M2925-31. Epub 2015 Nov 10. PMID: 26556797

Article Published Date : Nov 30, 2015

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Clostridium Infections

Pharmacological Actions : Antimicrobial, Gastroprotective

Additional Keywords : Gene Expression Regulation

[+]

EGCG has strong pharmacological activity against the development of morphine dependence. Sep 01, 2007

Click here to read the entire abstract

Pubmed Data : Arch Pharm Res. 2007 Sep;30(9):1111-5. PMID: 17958328

Article Published Date : Sep 01, 2007

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Morphine Tolerance/Dependence

[+]

EGCG has the potential to ameliorate high fat and high fructose diet-triggered learning and memory loss.Jul 23, 2017

Click here to read the entire abstract

Pubmed Data : FASEB J. 2017 Jul 24. Epub 2017 Jul 24. PMID: 28739640

Article Published Date : Jul 23, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : High Fat Diet, High Fructose Diet, Memory Loss

Pharmacological Actions : Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

EGCG has the potential to help control hyperglycemia, reduce weight, and alleviate diabetes complications.Dec 28, 2016

Click here to read the entire abstract

Pubmed Data : Biomed Pharmacother. 2016 Dec 29 ;87:73-81. Epub 2016 Dec 29. PMID: 28040599

Article Published Date : Dec 28, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Advanced Glycation End products (AGE), Diabetic Complications, Hyperglycemia

Pharmacological Actions : Anti-Glycation Agents, Hypoglycemic Agents, Hypolipidemic

[+]

EGCG improved lung damage in P. aeruginosa infection by inhibiting the production.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Microbiol. 2022 ;13:874354. Epub 2022 Apr 25. PMID: 35547130

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Lung Damage, Pseudomonas aeruginosa

Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-4 downregulation, Interleukin-6 Downregulation, Quorum Sensing Inhibition, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

EGCG induced a reduction in Aβ accumulation and elevated neprilysin expression in vitro.May 14, 2015

Click here to read the entire abstract

Pubmed Data : Exp Cell Res. 2015 May 15 ;334(1):136-45. Epub 2015 Apr 14. PMID: 25882496

Article Published Date : May 14, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Pharmacological Actions : Neuroprotective Agents

[+]

EGCG induces miRNA profile changes in the NNK-induced A/J mouse lung tumor.Dec 31, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Genomics. 2014 ;15 Suppl 11:S3. Epub 2014 Dec 16. PMID: 25559244

Article Published Date : Dec 31, 2013

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Lung Cancer

Pharmacological Actions : Anticarcinogenic Agents, MicroRNA modulator, NF-kappaB Inhibitor

Additional Keywords : Gene Expression Regulation

[+]

EGCG inhibited SW780 bladder cancer tumor growth by down-regulation of NF-κB and MMP-9.Dec 19, 2016

Click here to read the entire abstract

Pubmed Data : J Nutr Biochem. 2016 Dec 20 ;41:56-64. Epub 2016 Dec 20. PMID: 28040581

Article Published Date : Dec 19, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Bladder Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor

[+]

EGCG inhibits arsenic-induced inflammation and apoptosis through suppression of oxidative stress in mice.Apr 02, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cell Physiol Biochem. 2017 Apr 3 ;41(5):1788-1800. Epub 2017 Apr 3. PMID: 28365685

Article Published Date : Apr 02, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Arsenic Poisoning

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Problem Substances : Arsenic

[+]

EGCG inhibits fibroid tumors in quail. Feb 01, 2008

Click here to read the entire abstract

Pubmed Data : Nutr Res. 2008 Feb;28(2):92-7. PMID: 19083394

Article Published Date : Feb 01, 2008

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Fibroid Tumor, Fibroids: Uterine, Leiomyoma

Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

EGCG is a strong combination partner of gemcitabine reducing pancreatic cancer cell growth by suppressing glycolysis.Oct 04, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancers (Basel). 2019 Oct 5 ;11(10). Epub 2019 Oct 5. PMID: 31590367

Article Published Date : Oct 04, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Pancreatic Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Chemosensitizer

Additional Keywords : Cancer Glycolysis, Chemotherapeutic Synergy: Gemcitabine

[+]

EGCG is effective in inflammatory colitis because it reduces cellular and molecular inflammation, and reduces intestinal permeability.Jul 28, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2019 Jul 29 ;11(8). Epub 2019 Jul 29. PMID: 31362373

Article Published Date : Jul 28, 2019

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Colitis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

EGCG may ameliorate diet-induced metabolic misalignment by regulating the rhythmic expression of the circadian clock genes in the liver and fat.May 31, 2017

Click here to read the entire abstract

Pubmed Data : Biochim Biophys Acta. 2017 Jun ;1863(6):1575-1589. Epub 2017 Apr 12. PMID: 28412321

Article Published Date : May 31, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Metabolic Syndrome X, Obesity

Additional Keywords : Anti-Obesity Agents, Circadian Clock Proteins, Gene Expression Regulation

[+]

EGCG may be a useful adjuvant therapeutic agent for the treatment of breast cancer.Apr 12, 2017

Click here to read the entire abstract

Pubmed Data : Pharmacol Rep. 2017 Apr 13 ;69(5):924-928. Epub 2017 Apr 13. PMID: 28646740

Article Published Date : Apr 12, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Breast Cancer

Pharmacological Actions : Apoptotic, Chemotherapeutic

Additional Keywords : Gene Expression Regulation, Natural Substances Versus Drugs

[+]

EGCG may be useful as an adjuvant therapy for bronchial asthma.Nov 27, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Med. 2017 Nov 28. Epub 2017 Nov 28. PMID: 29207033

Article Published Date : Nov 27, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Asthma: Bronchial

Pharmacological Actions : Anti-Inflammatory Agents

[+]

EGCG may be useful for reducing hepatotoxicity associated with oxidative stressJun 20, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2017 Jun 21. Epub 2017 Jun 21. PMID: 28658663

Article Published Date : Jun 20, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Arsenic Poisoning, Oxidative Stress

Pharmacological Actions : Antioxidants, Hepatoprotective, Nrf2 activation

Problem Substances : Arsenic

[+]

EGCG may possible have a clinically relevant therapeutic effect in preventing, delaying or even treating tardive dyskinesia.Mar 31, 2015

Click here to read the entire abstract

Pubmed Data : Pharmacol Biochem Behav. 2015 Apr ;131:71-6. Epub 2015 Feb 8. PMID: 25668129

Article Published Date : Mar 31, 2015

Study Type : Animal Study

Additional Links

Substances : Catechin , EGCG (Epigallocatechin gallate)

Diseases : Lipid Peroxidation, Oxidative Stress, Tardive Dyskinesia

Pharmacological Actions : Antioxidants

[+]

EGCG may potentially inhibit aging-induced cardiac hypertrophy, fibrosis, and apoptosis, thereby preserving cardiac function.Jan 31, 2018

Click here to read the entire abstract

Pubmed Data : J Cardiovasc Pharmacol. 2018 Feb ;71(2):65-75. PMID: 29419571

Article Published Date : Jan 31, 2018

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cardiac Hypertrophy

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

EGCG may provide a potential therapeutic candidate for ALS as a disease-modifying agent. Oct 01, 2007

Click here to read the entire abstract

Pubmed Data : Biomed Res. 2007 Oct;28(5):261-6. PMID: 16356650

Article Published Date : Oct 01, 2007

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Amyotrophic Lateral Sclerosis

[+]

EGCG may reduce atherosclerotic plaque and alleviate pathological damage in the cardiac tissue.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Contrast Media Mol Imaging. 2022 ;2022:8639139. Epub 2022 Jul 11. PMID: 35919501

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Coronary Artery Disease

Pharmacological Actions : Antioxidants, Cardioprotective, Heme oxygenase-1 up-regulation, Nrf2 activation

[+]

EGCG may regenerate the HOCl-production of MPO which is known to be impaired at chronic inflammatory diseases like RA.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2016 ;11(3):e0152518. Epub 2016 Mar 29. PMID: 27023113

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Rheumatoid Arthritis

Pharmacological Actions : Anti-Inflammatory Agents

[+]

EGCG may serve as a promising compound for regulating glucose homeostasis.Apr 02, 2019

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2019 Apr 3 ;67(13):3651-3661. Epub 2019 Mar 21. PMID: 30875211

Article Published Date : Apr 02, 2019

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Hyperglycemia

Pharmacological Actions : Hypoglycemic Agents

[+]

EGCG might be regarded as a prospective therapeutic candidate in modulating diabetic nephropathy.Aug 20, 2017

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2017 Aug 21. Epub 2017 Aug 21. PMID: 28823168

Article Published Date : Aug 20, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Diabetic Nephropathy

Pharmacological Actions : Anti-Apoptotic, Anti-Fibrotic, Hypoglycemic Agents

[+]

EGCG might represent a new potential therapeutic or preventive approach to control white spot syndrome.Jun 21, 2017

Click here to read the entire abstract

Pubmed Data : Fish Shellfish Immunol. 2017 Jun 22. Epub 2017 Jun 22. PMID: 28648884

Article Published Date : Jun 21, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Fish Diseases

Additional Keywords : Gene Expression Regulation

[+]

EGCG modulates the composition of the gut microbiota to protect against radiation-induced intestinal injury.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Oncol. 2022 ;12:848107. Epub 2022 Apr 11. PMID: 35480105

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Radiation

Pharmacological Actions : Gastroprotective, Radioprotective

[+]

EGCG modulates the reversal of gene silencing involved in colon carcinogenesis.May 05, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2016 May 6. Epub 2016 May 6. PMID: 27167203

Article Published Date : May 05, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Colon Cancer

Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive

Additional Keywords : Dose Response, Epigenetic Modification In Cancer, Gene Expression Regulation

[+]

EGCG nanoparticles attenuate aluminum chloride induced neurobehavioral deficits.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Aging Neurosci. 2018 ;10:244. Epub 2018 Aug 13. PMID: 30150930

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Aluminum Toxicity , Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Aluminum Chloride

[+]

EGCG possesses potent activity to attenuate lung injury during acute pancreatitis progression by inhibiting NLRP3 inflammasome activation.May 20, 2021

Click here to read the entire abstract

Pubmed Data : Food Funct. 2021 May 21. Epub 2021 May 21. PMID: 34018522

Article Published Date : May 20, 2021

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Lung Injury: Acute, Pancreatitis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

EGCG potentially abrogates fluoride induced oxidative lung injury in rats.Jul 25, 2016

Click here to read the entire abstract

Pubmed Data : Int Immunopharmacol. 2016 Jul 26 ;39:128-139. Epub 2016 Jul 26. PMID: 27472294

Article Published Date : Jul 25, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Fluoride Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Nrf2 activation

[+]

EGCG prevents cardiac hypertrophy induced by pressuer overload in rats. Jun 01, 2007

Click here to read the entire abstract

Pubmed Data : J Vet Sci. 2007 Jun;8(2):121-9. PMID: 17519564

Article Published Date : Jun 01, 2007

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cardiac Hypertrophy

[+]

EGCG promotes atherosclerotic lesion stability in apolipoprotein E-deficient mice.Jun 03, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Kardiol Pol. 2018 Jun 4. Epub 2018 Jun 4. PMID: 29862488

Article Published Date : Jun 03, 2018

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Coronary Artery Disease

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

EGCG promotes PRKCA expression to alleviate LPS-induced acute lung injury and inflammatory response.May 25, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2021 May 26 ;11(1):11014. Epub 2021 May 26. PMID: 34040072

Article Published Date : May 25, 2021

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Infection

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

EGCG protected against myocardial I/RI by modulating Gm4419/DUSP5/ERK1/2-mediated autophagy.Nov 01, 2021

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Pubmed Data : Toxicol Appl Pharmacol. 2021 Nov 2 ;433:115782. Epub 2021 Nov 2. PMID: 34740634

Article Published Date : Nov 01, 2021

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Myocardial Ischemia

Pharmacological Actions : Anti-Apoptotic, Cardioprotective

[+]

EGCG protected outer hair cells from gentamicin toxicity in a cochlear explant model.Sep 30, 2016

Click here to read the entire abstract

Pubmed Data : Otol Neurotol. 2016 Oct ;37(9):1449-56. PMID: 27631653

Article Published Date : Sep 30, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Chemotherapy-Induced Toxicity: Gentamicin

Pharmacological Actions : Antioxidants, Chemoprotective Agents

[+]

EGCG protects against muscle wasting disease, in a mouse model. Apr 14, 2010

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Pubmed Data : J Agric Food Chem. 2010 Apr 14;58(7):4523-8. PMID: 19322813

Article Published Date : Apr 14, 2010

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Muscle Atrophy , Muscular Dystrophies

Pharmacological Actions : Glutathione Upregulation

[+]

EGCG protects the kidney in diabetic mice via anti-oxidative stress pathway.May 09, 2016

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Pubmed Data : Zhonghua Yi Xue Za Zhi. 2016 May 10 ;96(17):1330-5. PMID: 27180749

Article Published Date : May 09, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Diabetes: Oxidative Stress, Diabetes Mellitus: Type 2

Pharmacological Actions : Antioxidants, Renoprotective

[+]

EGCG protects the mouse brain against cerebral ischemia/reperfusion injury.Dec 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2022 ;13:921394. Epub 2022 Sep 6. PMID: 36147330

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cerebral Ischemia, Stroke: Ischemic

Pharmacological Actions : Autophagy Inhibitors, Neuroprotective Agents

[+]

EGCG reduces the susceptibility to cholesterol gallstone formation through the regulation of inflammation.Dec 01, 2008

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Pubmed Data : Biomed Pharmacother. 2008 Dec;62(10):677-83. Epub 2008 Jan 30. PMID: 18374538

Article Published Date : Dec 01, 2008

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cholecystitis, Gallbladder Inflammation, Gallstones

[+]

EGCG reduces the testicular oxidative stress induced by arsenic poisoning and thereby protect the reproductive system.Oct 12, 2017

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Pubmed Data : Biomed Pharmacother. 2017 Oct 13 ;96:685-694. Epub 2017 Oct 13. PMID: 29040955

Article Published Date : Oct 12, 2017

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Arsenic Poisoning, Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Antioxidants

[+]

EGCG restores keratinocyte autophagy to promote diabetic wound healing.Nov 30, 2023

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Pubmed Data : Front Biosci (Landmark Ed). 2023 Dec 1 ;28(12):324. PMID: 38179734

Article Published Date : Nov 30, 2023

Study Type : Animal Study

Additional Links

Substances : Catechin , EGCG (Epigallocatechin gallate)

Diseases : Wound Healing

[+]

EGCG reversed GIO in rats by protecting osteoblasts by activating the Nrf2 signaling pathway.Dec 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2018 ;9:447. Epub 2018 May 9. PMID: 29867459

Article Published Date : Dec 31, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Osteoporosis

Pharmacological Actions : Antioxidants, Nrf2 activation, Osteoprotective

[+]

EGCG sensitizes breast cancer cells to paclitaxel in a mouse model of breast carcinoma.Jan 15, 2010

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Pubmed Data : Breast Cancer Res. 2010 Jan 15;12(1):R8. Epub 2010 Jan 15. PMID: 20078855

Article Published Date : Jan 15, 2010

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Breast Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Drug: Paclitaxel

[+]

EGCG significantly inhibited gastric tumour growth in vivo by inhibiting Wnt/β-catenin signalling. Jun 23, 2016

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Pubmed Data : Int J Food Sci Nutr. 2016 Jun 24:1-10. Epub 2016 Jun 24. PMID: 27338284

Article Published Date : Jun 23, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Gastric Cancer

Pharmacological Actions : Antiproliferative , Chemopreventive, Wnt/β-catenin pathway down-regulation

[+]

EGCG supplement specifically counteracts daytime overeating induced by high fat diet in mice.Jul 27, 2016

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Pubmed Data : Mol Nutr Food Res. 2016 Jul 28. Epub 2016 Jul 28. PMID: 27468160

Article Published Date : Jul 27, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : High Fat Diet

Pharmacological Actions : Appetite Depressants

Additional Keywords : Gene Expression Regulation

[+]

EGCG supplementation before radioiodine therapy could protect from RI-induced SG damage in a manner comparable to amifostine.May 02, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Exp Otorhinolaryngol. 2016 May 3. Epub 2016 May 3. PMID: 27136365

Article Published Date : May 02, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Chemotherapy and Radiation Toxicity

Pharmacological Actions : Radioprotective

Additional Keywords : Natural Substances Versus Drugs

[+]

EGCG treatment can decrease renal ischemia-reperfusion injury by suppressing inflammation and cell apoptosis.Jun 27, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int Urol Nephrol. 2015 Jun 28. Epub 2015 Jun 28. PMID: 26122117

Article Published Date : Jun 27, 2015

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Kidney Damage, Kidney Diseases

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Renoprotective

Additional Keywords : Significant Treatment Outcome

[+]

EGCG treatment led to a significant decrease in the protein levels of three Alzheimer’s disease relevant phospho-tau epitopes.Jul 23, 2015

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Pubmed Data : Nutr Neurosci. 2015 Jul 24. Epub 2015 Jul 24. PMID: 26207957

Article Published Date : Jul 23, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Alzheimer's Disease

Pharmacological Actions : MicroRNA modulator, Neuroprotective Agents

[+]

EGCG treatment was able to prevent the decreased locomotor activity as well as improve the learning and memory in SRs.Jun 26, 2015

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Pubmed Data : Neurosci Lett. 2015 Jun 27 ;602:27-32. Epub 2015 Jun 27. PMID: 26126814

Article Published Date : Jun 26, 2015

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Learning disorders, Oxidative Stress

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

EGCG was able to exert anti-benign prostatic hyperplasia activities in metabolic syndrome rats.Jun 14, 2016

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Pubmed Data : Environ Toxicol Pharmacol. 2016 Jun 15 ;45:315-320. Epub 2016 Jun 15. PMID: 27348728

Article Published Date : Jun 14, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Metabolic Syndrome X, Prostatic Hyperplasia: Benign

Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents, Hypolipidemic

[+]

EGCG, a green tea polyphenol, inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer in vivo. Jan 01, 2008

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Pubmed Data : Front Biosci. 2008 Jan 1;13:440-52. PMID: 17981559

Article Published Date : Jan 01, 2008

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Pancreatic Cancer

Pharmacological Actions : Anti-Angiogenic

[+]

EGCG, a green tea polyphenol, prevents photocarcinogenesis in mice by enhancing DNA repair. May 15, 2006

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Pubmed Data : Cancer Res. 2006 May 15;66(10):5512-20. PMID: 16707481

Article Published Date : May 15, 2006

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Skin Diseases: Photo-Aging, Xeroderma Pigmentosum

[+]

EGCG, a green tea polyphenol, significantly interferes with androgen-independent prostate cancer in vivo. Jan 01, 2008

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Pubmed Data : Nutr Cancer. 2008;60(4):483-91. PMID: 18584482

Article Published Date : Jan 01, 2008

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Prostate Cancer

Pharmacological Actions : Anti-Angiogenic, Apoptotic

Additional Keywords : Androgen-Independent Prostate Cancer

[+]

EGCG, a polyphenol from green tea, ameloriates chronic fatigue syndrome in mice. Jul 27, 2009

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Pubmed Data : Behav Brain Res. 2009 Jul 27. PMID: 19643148

Article Published Date : Jul 27, 2009

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Chronic Fatigue Syndrome

[+]

EGCG-containing supplements may be important in correcting skeletal deficits associated with Down syndrome.Jan 08, 2016

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Pubmed Data : Mol Nutr Food Res. 2016 Jan 9. Epub 2016 Jan 9. PMID: 26748562

Article Published Date : Jan 08, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Down Syndrome

Additional Keywords : Gene Expression Regulation

[+]

EGCG-induced vascular normalization in human lung adenocarcinoma may be a novel modality for enhancing chemotherapy effects.Dec 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancer Manag Res. 2019 ;11:2425-2439. Epub 2019 Mar 27. PMID: 30988640

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Lung Cancer

Pharmacological Actions : Chemotherapeutic

Additional Keywords : Chemotherapeutic Synergy: Cisplatin

[+]

EGCG3''Me supplemented diet produces promising effects on gut micro-ecology by enhancing beneficial microbial populations.May 14, 2018

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Pubmed Data : Mol Nutr Food Res. 2018 May 15:e1800274. Epub 2018 May 15. PMID: 29762899

Article Published Date : May 14, 2018

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Obesity

Pharmacological Actions : Gastrointestinal Agents

[+]

Encapsulation of EGCG in transferrin-bearing vesicles is a promising therapeutic strategy.Jan 31, 2013

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Pubmed Data : Nanomedicine (Lond). 2013 Feb ;8(2):181-92. Epub 2012 Aug 14. PMID: 22891867

Article Published Date : Jan 31, 2013

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Melanoma, Squamous cell carcinoma

Pharmacological Actions : Antiproliferative

[+]

Epigallocatechin gallate (EGCG) alleviates inflammation and endothelial dysfunction and improves pregnancy outcomes in preeclampsia.May 21, 2024

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Pubmed Data : J Reprod Immunol. 2024 May 22 ;164:104263. Epub 2024 May 22. PMID: 38838579

Article Published Date : May 21, 2024

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Pre-Eclampsia

Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation

[+]

Epigallocatechin gallate (EGCG) alleviates the inflammatory response and recovers oral microbiota in acetic acid-induced oral inflammation.Nov 12, 2023

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Pubmed Data : Food Funct. 2023 Nov 13 ;14(22):10069-10082. Epub 2023 Nov 13. PMID: 37867423

Article Published Date : Nov 12, 2023

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Epigallocatechin gallate (EGCG) alters body fat and lean mass through sex-dependent metabolic mechanisms in Drosophila melanogaster.Apr 21, 2019

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Pubmed Data : Int J Food Sci Nutr. 2019 Apr 22:1-11. Epub 2019 Apr 22. PMID: 31010351

Article Published Date : Apr 21, 2019

Study Type : Insect Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Obesity

Additional Keywords : Anti-Obesity Agents

[+]

Epigallocatechin gallate (EGCG) attenuates myocardial hypertrophy and fibrosis induced by transverse aortic constriction via inhibiting the Akt/mTOR pathway.Nov 30, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pharm Biol. 2021 Dec ;59(1):1305-1313. PMID: 34607503

Article Published Date : Nov 30, 2021

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cardiac Hypertrophy, Myocardial Fibrosis

Pharmacological Actions : Anti-Fibrotic, Cardioprotective

[+]

Epigallocatechin gallate (EGCG) reduces coronavirus replication.Jan 16, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Viruses. 2021 12 17 ;13(12). Epub 2021 Dec 17. PMID: 34960802

Article Published Date : Jan 16, 2021

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Coronavirus Infection

Pharmacological Actions : Antiviral Agents

[+]

Epigallocatechin gallate alleviates high-fat diet-induced hepatic lipotoxicity.Dec 31, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2023 ;14:1148814. Epub 2023 Mar 21. PMID: 37025486

Article Published Date : Dec 31, 2022

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : High Fat Diet, Liver Damage, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Antioxidants, Hepatoprotective, Hypolipidemic

[+]

Epigallocatechin gallate alleviates non-alcoholic fatty liver disease.Jun 18, 2024

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Pubmed Data : Clin Nutr. 2024 Jun 19 ;43(8):1769-1780. Epub 2024 Jun 19. PMID: 38936303

Article Published Date : Jun 18, 2024

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Hypolipidemic

[+]

Epigallocatechin gallate alleviates osteoporosis by regulating the gut microbiota and serum metabolites.Nov 26, 2023

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Pubmed Data : Food Funct. 2023 Nov 27 ;14(23):10564-10580. Epub 2023 Nov 27. PMID: 37953732

Article Published Date : Nov 26, 2023

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Osteoporosis

Pharmacological Actions : Gastrointestinal Agents, Osteoprotective

[+]

Epigallocatechin gallate ameliorates airway inflammation by regulating Treg/Th17 imbalance in an asthmatic mouse model.Apr 24, 2019

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Pubmed Data : Int Immunopharmacol. 2019 Apr 25 ;72:422-428. Epub 2019 Apr 25. PMID: 31030098

Article Published Date : Apr 24, 2019

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Asthma

Pharmacological Actions : Immunomodulatory, Interleukin-10 upregulation

[+]

Epigallocatechin gallate ameliorates nicotine withdrawal conditions-induced somatic and affective behavior changes.Dec 31, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Behav Neurol. 2023 ;2023:5581893. Epub 2023 Jun 13. PMID: 37346971

Article Published Date : Dec 31, 2022

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Nicotine/Tobacco Toxicity

Pharmacological Actions : MicroRNA modulator

[+]

Epigallocatechin gallate and coenzyme Q10 attenuate cisplatin-induced hepatotoxicity.Jan 03, 2021

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Pubmed Data : J Biochem Mol Toxicol. 2021 Jan 4:e22701. Epub 2021 Jan 4. PMID: 33393703

Article Published Date : Jan 03, 2021

Study Type : Animal Study

Additional Links

Substances : Coenzyme Q10, EGCG (Epigallocatechin gallate)

Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Liver Damage: Drug-Induced

Pharmacological Actions : Chemoprotective Agents, Hepatoprotective

[+]

Epigallocatechin gallate and epicatechin gallate inhibited the cytotoxicity of acrylamide in PC12 cells.Oct 25, 2017

Click here to read the entire abstract

Pubmed Data : Drug Chem Toxicol. 2017 Oct 26:1-8. Epub 2017 Oct 26. PMID: 29072525

Article Published Date : Oct 25, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Epicatechin

Diseases :

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View the Evidence: 818 Abstracts with EGCG (Epigallocatechin gallate) Research

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Consumption of green tea EGCG resulted in a significant reduction of low-density lipoprotein cholesterol.Jun 19, 2016

Sulforaphane and EGCG restore estrogen receptor expression by modulating epigenetic events in the breast cancer cell line MDA-MB-231.Oct 17, 2017

The effects of green tea on weight loss and weight maintenance.Aug 31, 2009

Therapeutic effects of epigallocatechin-3-gallate for inflammatory bowel disease.May 31, 2024

A presurgical study of lecithin formulation of green tea extract in women with early breast cancer.May 31, 2017

Addition of epigallocatechin gallate 400 mg to sofosbuvir 400 mg + daclatisvir 60 mg in in treatment of patients with chronic hepatitis C.Jan 18, 2019

Administration of polyphenon E resulted in a therapeutic benefit for patients who were refractory to 5-aminosalicylic and/or azathioprine.Jul 31, 2013

AverTeaX formulation containing lipophilic catechins effectively inhibited herpes simplex labialis infection with clinical significance.Nov 30, 2015

Both both zonal priming and direct EGCG application in scar therapy has positive effects on scar thickness, erythema, hydration and elasticity.Feb 25, 2019

Both EGCG and green tea could be used as alternatives to chlorhexidine-based mouthwashes.Apr 18, 2020

Cysteamine plus epigallocatechin gallate can be used for autophagy-dependent rescue of class II-mutated CFTR.Mar 31, 2016

Decaffeinated green tea extract resulted in significant reductions in lesions located on the nose, perioral area and chin.Mar 31, 2016

Decreases in inflammatory levels in patients with multiple sclerosis after treatment with epigallocatechin gallate and coconut oil.Sep 15, 2021

Efficacy and safety of EGCG oxygen nebulization inhalation in the treatment of COVID-19 pneumonia patients with cancer.Apr 16, 2024

Efficacy of EGCG in preventing dermatitis in patients with breast cancer receiving postoperative radiotherapy.May 31, 2022

EGCG activated AMPK and insulin pathways, thereby promoting glycolysis, glycogen, and protein synthesis and inhibiting fatty acid and cholesterol synthesis.Nov 16, 2021

EGCG and coconut oil improve state anxiety and functional capacity in patients with multiple sclerosis.Jan 22, 2020

EGCG and cognitive training for 12 months led to an improving of visual recognition memory, inhibitory control, and adaptive behaviour.Jun 30, 2016

EGCG decreased skeletal muscle lactate concentrations in overweight individuals, suggesting a shift towards a more oxidative muscle phenotype.Dec 31, 2014

EGCG enhances fat oxidation in men and may contribute to the anti-obesity effects of green tea. Oct 22, 2010

EGCG given to patients with multiple sclerosis over 12 weeks improved muscle metabolism during moderate exercise to a greater extent in men than in women.Feb 28, 2015

EGCG supplementation may be improved blood pressure, lipid profile, AIP, and oxidative status in patients with T2DM.Dec 24, 2020

Epigallocatechin gallate could potentially be used as a supplement of traditional rt-PA treatment among stroke patients.Dec 08, 2016

Epigallocatechin gallate decreases plasma triglyceride, blood pressure, and serum kisspeptin in obese human subjects.Jan 11, 2020

Epigallocatechin gallate enhances treatment efficacy of oral nifedipine against pregnancy-induced severe pre-eclampsia.Jan 31, 2018

Epigallocatechin-3-gallate mouthwash protects mucosa from radiation-induced mucositis in head and neck cancer patients.Dec 31, 2019

Green tea catechins are effective in reducing atherosclerosis risk associated with oxidative stress.Dec 31, 2015

Green tea catechins may have a therapeutic role in the treatment of metabolic syndrome. Jan 01, 2009

Green tea polyphenon E and erlotinib combination was well tolerated in patients with APLs of the head and neck.Jan 14, 2020

High-dose green tea extract resulted in significant weight loss, reduced waist circumference, and a consistent decrease in total cholesterol and LDL plasma levels.May 28, 2015

Improvements in gait and balance in patients with multiple sclerosis after treatment with coconut oil and epigallocatechin gallate.Jan 22, 2023

It appears that EGCG should be taken without food in order to maximise its systemic absorption.Dec 31, 2014

Phase II trial of epigallocatechin-3-gallate in acute radiation-induced esophagitis for esophagus cancer.Dec 31, 2019

Supplementation with green tea extract significantly reduced circulating triglycerides and LDL-cholesterol concentrations.Nov 01, 2016

Tea polyphenol has potential to be a therapeutic adjuvant against human metastatic breast cancer.Feb 01, 2012

Tea polyphenols (primarily EGCG), significantly reduce PSA, Hepatocyte growth factor, VEG in men with prostate cancer. Jul 01, 2009

The administration of EGCG and coconut oil seems to decrease blood triglyceride levels.Oct 10, 2023

The association between green and black tea consumption on successful aging.May 14, 2019

The effect of (-)-epigallocatechin gallate as an adjunct to non-surgical periodontal treatment.May 02, 2022

The inhalation of tea catechin appears to suppress MRSA infection in the elderly. Feb 01, 2006

Topical EGCG may be an effective treatment for radiation-induced dermatitis and has acceptable toxicity.May 19, 2016

Topical epigallocatechin-3-gallate in the treatment of vitiligo.Jul 31, 2021

Topical green tea extract appears safe and effective in treating external anogenital warts. Jan 01, 2006

Twelve weeks of EGCG and resveratrol supplementation increased mitochondrial capacity and stimulated fat oxidation.May 17, 2016

Usage of and attitudes about green tea extract and epigallocathechin-3-gallate as a therapy in individuals with Down syndrome.Jul 31, 2019

Combinations of EGCG and anticancer compounds induced synergistic anticancer effects in vitro and in vivo experiments, and showed an average reduction in tumor volume by 70.3 %.Aug 31, 2015

EGCG protected against the effects of Dihydrotestosterone (DHT) by altering the miRNA expression profile in human dermal papilla cells.May 31, 2016

Epigallocatechin gallate suppresses Chlamydia pneumoniae mediated IgE responses.Jun 15, 2016

Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome.Jan 01, 2013

Panaxadiol and Epigallocatechin Gallate have a synergistic apoptotic effect on human colorectal cancer cells.May 08, 2012

Punicalagin and EGCG can rescue keratinocyte viability and attenuate the inflammatory responses of cells due to airborne particles.Mar 21, 2018

These results provide new evidence for the effectiveness of EGCG in vitiligo treatment.Sep 03, 2015

VEGF is a key molecular target for specific polyphenols found in tea, apples and cocoa which potently inhibit VEGF signalling and angiogenesis at physiological concentrations.Feb 28, 2015

A case of complete and durable molecular remission of chronic lymphocytic leukemia following treatment with epigallocatechin-3-gallate.Dec 31, 2014

Co-delivery of EGCG and melittin with self-assembled fluoro-nanoparticles for enhanced cancer therapy.Jun 04, 2023

EGCG disrupts the LIN28B/Let-7 interaction and reduces neuroblastoma aggressiveness.Apr 26, 2024

Epicatechin gallate blocked cellular foam formation in atherosclerosis.Mar 05, 2023

Epigallocatechin-3-gallate improves the quality of maternally aged oocytes.Nov 26, 2023

Synergetic EGCG and coenzyme Q10 DSPC liposome nanoparticles protect against myocardial infarction.Oct 09, 2023

The anti-cancer effect of epigallocatechin-3-O-gallate against multiple myeloma cells is potentiated by 5,7-dimethoxyflavone.Oct 31, 2023

Epigallocatechin gallate but not catechin prevents nonalcoholic steatohepatitis in mice similar to green tea extract while differentially affecting the gut microbiota.Jun 19, 2020

Sex-specific oxidative damage effects induced by BPA and its analogs on primary hippocampal neurons attenuated by EGCG.Sep 27, 2020

Synergistic Effect of β-cryptoxanthin and epigallocatechin gallate on obesity reduction. Jul 19, 2024

The green tea polyphenol epigallocatechin-3-gallate attenuates age-associated muscle loss via regulation of miR-486-5p and myostatin.Jul 21, 2020

"Amelioration of influenza virus-induced reactive oxygen species formation by epigallocatechin gallate derived from green tea."Nov 30, 2012

"Green tea catechins ameliorates adipose Insulin resistance by improving oxidative stress."Feb 11, 2012

"Green tea epigallocatechin-3-gallate (EGCG) promotes neural progenitor cell proliferation and sonic hedgehog pathway activation during adult hippocampal neurogenesis."Jul 31, 2012

"Green tea epigallocatechin-3-gallate attenuates Porphyromonas gingivalis-induced atherosclerosis."Sep 10, 2012

(-)-Epigallocatechin-3-gallate (EGCG) can inhibit the proliferation and invasiveness and induce apoptosis in nasopharyngeal carcinoma cells.Dec 31, 2014

A combination of nutrients improves cognitive functioning while decreasing Alzheimer disease neuropathology in an animal model.Jan 01, 2010

A major metabolite of EGCG increased the activity of CD4(+) T cells and enhanced the cytotoxic activity of NK cells in vivo.May 10, 2016

A quercetin, EGCG and apple polyphenol concentrate improved disorders of lipid metabolism and pro-oxidant-antioxidant homeostasis.Dec 31, 2016

EGCG (Epigallocatechin gallate)

View the Evidence:
818 Abstracts with EGCG (Epigallocatechin gallate) Research