Endocannabinoids

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35 Diseases Researched for Endocannabinoids
NameACCKFocus
Anorexia110Locked
Endocannabinoid Disorders110Locked
Cancers: All89Locked
Colorectal Cancer15Locked
Cancer Metastasis34Locked
Inflammation34Locked
Diabetes Mellitus: Type 1: Prevention23Locked
Endocannabinoid System33Locked
Bladder Cancer12Locked
Brain Edema12Locked
Brain Inflammation 12Locked
Cachexia22Locked
Melanoma: Metastasis12Locked
Prostate Cancer22Locked
Traumatic Brain Injury12Locked
Acne11Locked
Allergies11Locked
Alzheimer's Disease11Locked
Amyotrophic lateral sclerosis (ALS)11Locked
Asthma11Locked
Breast Cancer11Locked
Cancer: Pain 11Locked
Cardiovascular Diseases11Locked
Chronic Pain11Locked
Depression11Locked
Dermatitis11Locked
Diabetes Mellitus: Type 211Locked
Dry Skin 11Locked
Glioma11Locked
Immune Disorders11Locked
Multiple Sclerosis11Locked
Obesity11Locked
Psoriasis11Locked
Seborrheic Keratosis11Locked
Skin Cancer11Locked
16 Pharmacological Actions Researched for Endocannabinoids
NameACCKFocus
Antiproliferative 56Locked
Apoptotic56Locked
Neuroprotective Agents45Locked
Anti-Inflammatory Agents23Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor23Locked
Anti-metastatic22Locked
Anticarcinogenic Agents22Locked
Immunomodulatory12Locked
Analgesics11Locked
Angiogenesis Inhibitors11Locked
Anti-Apoptotic11Locked
Antineoplastic Agents11Locked
Cannabinoid Receptor Antagonist/Inverse Agonist11Locked
Chemotherapeutic11Locked
Immunosuppressive Agents11Locked
Neuritogenic11Locked

View the Evidence:
21 Abstracts with Endocannabinoids Research

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Endocannabinoids and endocannabinoid related compounds are involved in food related reward and suggest a dysregulation of their physiology in anorexia nervosa.Jan 31, 2015

Pubmed Data : Am J Clin Nutr. 2015 Feb ;101(2):262-9. Epub 2014 Dec 10. PMID: 25646322
Article Published Date : Jan 31, 2015
Study Type : Human Study
Additional Links
Substances : Anandamide, Endocannabinoids
Diseases : Anorexia, Endocannabinoid Disorders
Additional Keywords : Diseases that are Linked, Endocannabinoid System
[+]

Endocannabinoid and ceramide levels are altered in patients with colorectal cancer.Jun 30, 2015

Pubmed Data : Oncol Rep. 2015 Jul ;34(1):447-54. Epub 2015 May 12. PMID: 25975960
Article Published Date : Jun 30, 2015
Study Type : Human In Vitro
Additional Links
Substances : Endocannabinoids
Diseases : Colorectal Cancer
Additional Keywords : Cannabinoid Receptors, Endocannabinoid System
[+]

Administration of synthetic 2-AG to mice after CHI led to significant reduction of brain oedema, better clinical recovery, reduced infarct volume and reduced hippocampal cell death compared with controls.Oct 03, 2001

Pubmed Data : Nature. 2001 Oct 4 ;413(6855):527-31. PMID: 11586361
Article Published Date : Oct 03, 2001
Study Type : Animal Study
Additional Links
Substances : Cannabinoids , Endocannabinoids
Diseases : Brain Edema, Brain Inflammation , Traumatic Brain Injury
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Significant Treatment Outcome
[+]

Endocannabinoid system acts as a regulator of immune homeostasis in the gutApr 23, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Proc Natl Acad Sci U S A. 2017 Apr 24. Epub 2017 Apr 24. PMID: 28439004
Article Published Date : Apr 23, 2017
Study Type : Animal Study
Additional Links
Substances : Anandamide, Endocannabinoids
Diseases : Diabetes Mellitus: Type 1: Prevention
Pharmacological Actions : Immunomodulatory
Additional Keywords : Endocannabinoid System
[+]

The endocannabinoid system was subject to cancer-associated regulations to an extent that led to measurable changes in circulating endocannabinoid levels.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncoscience. 2014 ;1(4):272-82. Epub 2014 Apr 30. PMID: 25594019
Article Published Date : Dec 31, 2013
Study Type : Insect Study
Additional Links
Substances : Endocannabinoids
Diseases : Cancer Metastasis, Cancers: All, Melanoma: Metastasis
Additional Keywords : Endocannabinoid System
[+]

The in vivo assessment of the role of CB receptors in inflammation and cancer might be instrumental in broadening the understanding about bladder cancer biology.Sep 30, 2015

Pubmed Data : Life Sci. 2015 Oct 1 ;138:41-51. Epub 2014 Oct 15. PMID: 25445433
Article Published Date : Sep 30, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cannabinoids , Endocannabinoids
Diseases : Bladder Cancer, Inflammation
Pharmacological Actions : Antiproliferative , Apoptotic, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Cannabinoid Receptors
[+]

Cannabinoid type 1 receptor activation stimulates appetite and promotes lipogenesis and energy storage.Jun 30, 2007

Pubmed Data : Curr Opin Clin Nutr Metab Care. 2007 Jul ;10(4):443-8. PMID: 17563462
Article Published Date : Jun 30, 2007
Study Type : Review
Additional Links
Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC), Endocannabinoids
Diseases : Cachexia
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cannabinoids and endocannabinoids may have therapeutic value in metabolic disorders and diabetes.Jan 01, 2011

Pubmed Data : Handb Exp Pharmacol. 2011(203):75-104. PMID: 21484568
Article Published Date : Jan 01, 2011
Study Type : Review
Additional Links
Substances : Cannabinoids , Cannabis, Endocannabinoids
Diseases : Diabetes Mellitus: Type 1: Prevention, Diabetes Mellitus: Type 2, Endocannabinoid System
Additional Keywords : Beta Cell Protection
[+]

Cannabinoids may be promising tools in combination therapy for breast and prostate cancers.Oct 31, 2016

Pubmed Data : Expert Opin Investig Drugs. 2016 Nov ;25(11):1311-1323. Epub 2016 Aug 28. PMID: 27633508
Article Published Date : Oct 31, 2016
Study Type : Review
Additional Links
Substances : Cannabidiol, Cannabinoids , Cannabinoids: Synthetic, Endocannabinoids
Diseases : Breast Cancer, Prostate Cancer
Pharmacological Actions : Chemotherapeutic
[+]

Endocannabinoids may be a beneficial option for the treatment of prostate cancer that has become nonresponsive to common therapies.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Rep. 2015 Apr ;33(4):1599-608. Epub 2015 Jan 21. PMID: 25606819
Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Anandamide, Cannabinoids: Synthetic, Endocannabinoids
Diseases : Prostate Cancer
Pharmacological Actions : Apoptotic
[+]

Observations support that endocannabinoids constitute a new family of lipid signaling cues responsible for the regulation of neural progenitor proliferation and differentiation.Dec 31, 2005

Pubmed Data : Curr Pharm Des. 2006 ;12(18):2319-25. PMID: 16787257
Article Published Date : Dec 31, 2005
Study Type : Review
Additional Links
Substances : Anandamide, Endocannabinoids
Diseases : Glioma
Pharmacological Actions : Anti-Apoptotic, Antiproliferative , Apoptotic, Neuritogenic, Neuroprotective Agents
[+]

Polyunsaturated fatty acids and endocannabinoids in health and disease.Jul 06, 2017

Pubmed Data : Nutr Neurosci. 2017 Jul 7:1-20. Epub 2017 Jul 7. PMID: 28686542
Article Published Date : Jul 06, 2017
Study Type : Review
Additional Links
Substances : Endocannabinoids, Polyunsaturated Fatty Acids (PUFAs)
Diseases : Alzheimer's Disease, Cardiovascular Diseases, Depression, Obesity
Pharmacological Actions : Neuroprotective Agents
[+]

Some studies have thus far shown evidence to support the use of cannabinoids for some cancer, neuropathic, spasticity, acute pain, and chronic pain conditions.Sep 30, 2015

Pubmed Data : Curr Pain Headache Rep. 2015 Oct ;19(10):524. PMID: 26325482
Article Published Date : Sep 30, 2015
Study Type : Review
Additional Links
Substances : Cannabidiol, Cannabinoids , Cannabinoids: Synthetic, Cannabis, Delta-tetrahydrocannabinol (THC), Endocannabinoids
Diseases : Cancer: Pain , Cancers: All
Pharmacological Actions : Analgesics
[+]

Substances aiming at the endocannabinoid system may represent potential antimetastatics.May 10, 2016

Pubmed Data : Expert Opin Ther Targets. 2016 May 11:1-17. Epub 2016 May 11. PMID: 27070944
Article Published Date : May 10, 2016
Study Type : Review
Additional Links
Substances : Cannabinoids , Endocannabinoids
Diseases : Cancer Metastasis, Cancers: All
[+]

The endocannabinoid system controls the growth and metastasis of malignant cells.Apr 30, 2003

Pubmed Data : Recenti Prog Med. 2003 May ;94(5):194-8. PMID: 12723496
Article Published Date : Apr 30, 2003
Study Type : Review
Additional Links
Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC), Endocannabinoids
Diseases : Cancer Metastasis, Cancers: All, Endocannabinoid System
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
Additional Keywords : Cannabinoid Receptors
[+]

The experimental evidence reviewed in this article argues in favor of the therapeutic potential of these compounds in immune disorders and cancer.Jan 31, 2002

Pubmed Data : Prostaglandins Leukot Essent Fatty Acids. 2002 Feb-Mar;66(2-3):319-32. PMID: 12052046
Article Published Date : Jan 31, 2002
Study Type : Review
Additional Links
Substances : Cannabinoids , Endocannabinoids
Diseases : Cancers: All, Endocannabinoid System, Immune Disorders
Pharmacological Actions : Antiproliferative , Apoptotic, Immunosuppressive Agents
Additional Keywords : Cannabinoid Receptors
[+]

The possible role of cannabimimetic fatty acid derivatives in the pathological consequences of cancer and inflammation are examined.Oct 31, 2000

Pubmed Data : Chem Phys Lipids. 2000 Nov ;108(1-2):191-209. PMID: 11106791
Article Published Date : Oct 31, 2000
Study Type : Review
Additional Links
Substances : Anandamide, Cannabinoids , Endocannabinoids
Diseases : Asthma, Cachexia, Cancers: All, Chronic Pain, Inflammation
[+]

This review critically discusses the pharmacology of CB receptor activation as a novel therapeutic anticancer strategyJun 30, 2009

Pubmed Data : J Pharm Pharmacol. 2009 Jul ;61(7):839-53. PMID: 19589225
Article Published Date : Jun 30, 2009
Study Type : Review
Additional Links
Substances : Cannabinoids , Endocannabinoids
Diseases : Cancers: All
Pharmacological Actions : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Anticarcinogenic Agents, Antineoplastic Agents, Antiproliferative
Additional Keywords : Cannabinoid Receptors, Endocannabinoid System
[+]

This review discusses how the endocannabinoid system can help treat diseases of the skin.Jul 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Trends Pharmacol Sci. 2009 Aug ;30(8):411-20. Epub 2009 Jul 14. PMID: 19608284
Article Published Date : Jul 31, 2009
Study Type : Review
Additional Links
Substances : Endocannabinoids
Diseases : Acne, Allergies, Dermatitis, Dry Skin , Inflammation, Psoriasis, Seborrheic Keratosis, Skin Cancer
Pharmacological Actions : Anticarcinogenic Agents, Cannabinoid Receptor Antagonist/Inverse Agonist
Additional Keywords : Cannabinoid Receptors, Endocannabinoid System
[+]

This review discusses the potential of cannabinoid therapeutics as disease-modifying or symptom control agents for slowing disease progression in MS and ALS.Dec 31, 2014

Pubmed Data : Handb Exp Pharmacol. 2015 ;231:213-31. PMID: 26408162
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Cannabinoids , Cannabis, Endocannabinoids
Diseases : Amyotrophic lateral sclerosis (ALS), Multiple Sclerosis
Pharmacological Actions : Neuroprotective Agents
[+]

This review summarises the demonstrated antitumour actions of cannabinoids and indicating possible avenues for cannabinoids as antitumour agents.Nov 30, 2003

Pubmed Data : Expert Opin Ther Targets. 2003 Dec ;7(6):749-58. PMID: 14640910
Article Published Date : Nov 30, 2003
Study Type : Review
Additional Links
Substances : Cannabinoids , Endocannabinoids
Diseases : Cancers: All
Additional Keywords : Cannabinoid Receptors

Copyright: logos2012 / 123RF Stock Photo

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A Higher Level of Freedom: The Benefit of Cannabis to Health
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In a day and age where possession of an herb like cannabis – which grows freely on this Earth -- is an offense sometimes punishable by incarceration, it is important for us to reflect on how we arrived at this dark point in time. Herbs, after all, were put there by God. If you prefer the word Nature, the point is the same, and it was put best by Bob Marley when he said: "you can't tell God it [cannabis] is illegal."

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