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65 Diseases Researched for Fig
NameACCKFocus
Diabetes Mellitus: Type 2618Locked
Atopic Dermatitis212Locked
Oxidative Stress711Locked
Aging Skin110Locked
Constipation110Locked
Prediabetes110Locked
Warts110Locked
Wrinkles110Locked
Breast Cancer38Locked
DNA damage15Locked
Liver Cancer35Locked
Muscle Atrophy 15Locked
Cancers: All34Locked
Diabetic Complications24Locked
High Fat Diet24Locked
Ulcerative Colitis24Locked
Breast Cancer: Triple Negative 23Locked
Cancer Metastasis23Locked
Chemically-Induced Liver Damage23Locked
Obesity23Locked
Alcohol Toxicity 12Locked
Allergies12Locked
Alzheimer's Disease12Locked
Breast Cancer: Chemically-Induced12Locked
Cadmium Poisoning 12Locked
Cardiomyopathy12Locked
Chemotherapy-Induced Kidney Damage12Locked
Chemotherapy-Induced Toxicity: 5-fluorouracil 12Locked
Chemotherapy-Induced Toxicity: Cisplatin12Locked
Chemotherapy-Induced Toxicity: Doxorubicin12Locked
Chemotherapy-Induced Toxicity: Gentamicin12Locked
Chemotherapy-Induced Toxicity: Vincristine12Locked
Cognitive Decline/Dysfunction12Locked
Colorectal Cancer22Locked
Diabetes Mellitus: Type 112Locked
Diabetic Nephropathy12Locked
Diabetic Neuropathy12Locked
Epilepsy12Locked
Formaldehyde Toxicity12Locked
Hyperlipidemia12Locked
Hypertension12Locked
IgE-Mediated Hypersensitivity12Locked
Infertility: Male12Locked
Inflammation22Locked
Insulin Resistance12Locked
Liver Damage: Drug-Induced12Locked
Neuropathic Pain12Locked
Pesticide Toxicity 12Locked
Pseudomonas aeruginosa22Locked
Radiation12Locked
Seizures: Convulsive12Locked
Testicular Injury: Chemical/Metal Induced12Locked
Asthma11Locked
Cervical Cancer11Locked
Enterococcus Infections11Locked
Glioblastoma11Locked
Gram-Negative Bacterial Infections11Locked
Hepatitis B 11Locked
Hydrogen Peroxide Induced Toxicity11Locked
Infection: Antibiotic Resistant11Locked
Lipopolysaccharide-Induced Toxicity11Locked
Malaria11Locked
Prostate Cancer11Locked
Respiratory Syncytial Virus Infections11Locked
Rhinovirus Infection 11Locked
42 Pharmacological Actions Researched for Fig
NameACCKFocus
Antioxidants1635Locked
Hypoglycemic Agents619Locked
Anti-Inflammatory Agents613Locked
Anti-collagenase110Locked
Antiproliferative 79Locked
Chemopreventive39Locked
Apoptotic78Locked
Chemoprotective Agents48Locked
Renoprotective48Locked
Hepatoprotective47Locked
Immunomodulatory47Locked
Interleukin-1 beta downregulation27Locked
Interleukin-6 Downregulation27Locked
Cytoprotective36Locked
Cardioprotective24Locked
Malondialdehyde Down-regulation24Locked
NF-kappaB Inhibitor24Locked
Neuroprotective Agents24Locked
Anti-Bacterial Agents33Locked
Anti-metastatic23Locked
Antineoplastic Agents23Locked
Anti-Allergic Agents12Locked
Anti-Apoptotic12Locked
Anticholesteremic Agents12Locked
Anticonvulsants12Locked
Antihypertensive Agents12Locked
Antiviral Agents22Locked
Cell cycle arrest22Locked
Cytotoxic22Locked
Glutathione Upregulation 12Locked
Hypolipidemic12Locked
Insulin Sensitizers12Locked
Laxative12Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor12Locked
Pancreato Protective Agents12Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor12Locked
Alpha-amylase inhibitor11Locked
Alpha-glucosidase inhibitor 11Locked
Antifungal Agents11Locked
Antimalarials11Locked
Insulin-releasing11Locked
Prophylactic Agents11Locked

View the Evidence:
74 Abstracts with Fig Research

[+]

Efficacy and safety of fig leaf tea in adults with mild atopic dermatitis.Oct 24, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Oct 25 ;14(21). Epub 2022 Oct 25. PMID: 36364740
Article Published Date : Oct 24, 2022
Study Type : Human Study
Additional Links
Substances : Fig
Diseases : Atopic Dermatitis
Pharmacological Actions : Immunomodulatory
[+]

Fig fruit extract can be used instead of low potent corticosteroid in mild to moderate cases of atopic dermatitis.Nov 30, 2017

Pubmed Data : Complement Ther Med. 2017 Dec ;35:85-91. Epub 2017 Oct 13. PMID: 29154073
Article Published Date : Nov 30, 2017
Study Type : Human Study
Additional Links
Substances : Fig
Diseases : Atopic Dermatitis
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Fig fruit extracts is a possible adjunctive treatment for glycemic management of chronic metabolic disorders.Jul 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Jul 31 ;11(8). Epub 2019 Jul 31. PMID: 31370154
Article Published Date : Jul 30, 2019
Study Type : Human Study
Additional Links
Substances : Fig
Diseases : Diabetes Mellitus: Type 2, Prediabetes
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Dose Response, Plant Extracts
[+]

Fig tree latex is safe and effective in treating common warts. May 01, 2007

Pubmed Data : Int J Dermatol. 2007 May;46(5):524-6. PMID: 17472688
Article Published Date : May 01, 2007
Study Type : Human Study
Additional Links
Substances : Fig
Diseases : Warts
Additional Keywords : Natural Substances Versus Drugs
[+]

The combined formulation of fruit extracts showed excellent antioxidative and anti-collagenase activity as well as a significant effect on anti-wrinkle activity on human skin.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Cosmet Investig Dermatol. 2015 ;8:389-96. Epub 2015 Jul 16. PMID: 26203268
Article Published Date : Dec 31, 2014
Study Type : Human Study, In Vitro Study
Additional Links
Substances : Fig, Ginkgo biloba, Pomegranate, White Mulberry
Diseases : Aging Skin, Wrinkles
Pharmacological Actions : Anti-collagenase, Antioxidants
Additional Keywords : Dose Response, Natural Substances Versus Drugs, Plant Extracts
[+]

These results suggest that F. carica paste may have beneficial effects in subjects suffering from constipation.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asia Pac J Clin Nutr. 2016 ;25(3):487-96. PMID: 27440682
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Fig
Diseases : Constipation
Additional Keywords : Phytotherapy
[+]

Ficus carica attenuates denervated skeletal muscle atrophy.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Physiol. 2020 ;11:580223. Epub 2020 Dec 3. PMID: 33343385
Article Published Date : Dec 31, 2019
Study Type : Human In Vitro
Additional Links
Substances : Fig
Diseases : Muscle Atrophy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Fig leaf extract has potential for early-stage breast cancer chemoprevention.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Bioequivalence Bioavailab. 2019 ;11(2):19-28. Epub 2019 Apr 1. PMID: 31814674
Article Published Date : Dec 31, 2018
Study Type : Human In Vitro, Review
Additional Links
Substances : Fig
Diseases : Breast Cancer, DNA damage
Pharmacological Actions : Chemopreventive
Problem Substances : Diethylstilbestrol (DES)
[+]

F. religisoa protects against isoniazid, rifampicin and paracetamol induced oxidative liver injury in rats.Sep 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacognosy Res. 2013 Oct ;5(4):271-6. PMID: 24174821
Article Published Date : Sep 30, 2013
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Liver Damage: Drug-Induced, Oxidative Stress
Pharmacological Actions : Hepatoprotective
Additional Keywords : Plant Extracts
Problem Substances : Isoniazid, Paracetamol
[+]

Ficus carica polysaccharide attenuates DSS-induced ulcerative colitis in C57BL/6 mice.Jun 30, 2020

Pubmed Data : Food Funct. 2020 Jul 1 ;11(7):6666-6679. Epub 2020 Jul 13. PMID: 32658237
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Administration of Ficus carica reduces the effects of lead on the seminiferous tubules of adult rat testis.Sep 30, 2018

Pubmed Data : J Coll Physicians Surg Pak. 2018 Oct ;28(10):731-734. PMID: 30266113
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Cytoprotective
Problem Substances : Lead
[+]

Ameliorative or corrective effects of Fig " Ficus carica" extract on nickel-induced hepatotoxicity.Jun 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Res. 2022 Jul ;38(3):311-321. Epub 2022 Jan 18. PMID: 35874505
Article Published Date : Jun 30, 2022
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

An aqueous methanol extract of F. carica fruit exerted hypotensive and antihypertensive effects in glucose-induced hypertensive rats.Nov 30, 2017

Pubmed Data : Pharm Biol. 2017 Dec ;55(1):1047-1053. PMID: 28187689
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents
Additional Keywords : Plant Extracts
[+]

An extract of natural herbals restores antitumor immunosurveillance and can be applied for prevention or treatment of inflammation-related cancers.Mar 21, 2018

Pubmed Data : Biomed Pharmacother. 2018 Mar 22 ;102:420-427. Epub 2018 Mar 22. PMID: 29574282
Article Published Date : Mar 21, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dandelion , Fig, Ginseng
Diseases : Cancers: All, Liver Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, NF-kappaB Inhibitor
[+]

Antischistosomal effects of Ficus carica leaves extract and/or PZQ on Schistosoma mansoni infected mice.Feb 28, 2022

Pubmed Data : J Parasit Dis. 2022 Mar ;46(1):87-102. Epub 2021 Jul 29. PMID: 35299912
Article Published Date : Feb 28, 2022
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
[+]

Co-treatment with vitamin E, sulphoraphane and Ficus religiosa were found to be effective in reversing cadmium induced reproductive toxicity.Jul 31, 2014

Pubmed Data : Syst Biol Reprod Med. 2014 Aug ;60(4):199-205. Epub 2014 Apr 23. PMID: 24758558
Article Published Date : Jul 31, 2014
Study Type : Animal Study
Additional Links
Substances : Fig, Sulforaphane, Vitamin E
Diseases : Cadmium Poisoning , Oxidative Stress
Pharmacological Actions : Antioxidants, Cytoprotective
Additional Keywords : Plant Extracts
Problem Substances : Cadmium
[+]

Dietary supplementation of figs may be useful for the improvement of cognitive and behavioural deficits in Alzheimer's disease.Jun 17, 2014

Pubmed Data : Nutr Neurosci. 2014 Jun 18. Epub 2014 Jun 18. PMID: 24938828
Article Published Date : Jun 17, 2014
Study Type : Transgenic Animal Study
Additional Links
Substances : Fig
Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

Dried fig could be used to protect against the production of ethanol-induced free radicals and hepatotoxicity.Sep 30, 2016

Pubmed Data : Int J Biol Macromol. 2016 Oct ;91:554-9. Epub 2016 Jun 5. PMID: 27268385
Article Published Date : Sep 30, 2016
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Alcohol Toxicity , Chemically-Induced Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Effect of nano extracts of olea europaea leaves, ficus carica and liraglutide in lipidemic liver of type 2 diabetic rat model.Jun 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi J Biol Sci. 2022 Jul ;29(7):103333. Epub 2022 Jun 1. PMID: 35721230
Article Published Date : Jun 30, 2022
Study Type : Animal Study
Additional Links
Substances : Fig, Olive
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hepatoprotective
[+]

F. carica extract is more effective than L. sativum and P. granatum extracts in the prevention and control of type 2 diabetes mellitus (T2DM) and its consequences.Dec 31, 2020

Pubmed Data : J Diabetes Res. 2021 ;2021:6018835. Epub 2021 Dec 21. PMID: 34970629
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Fig, Garden Cress (Lepidium sativum) , Pomegranate
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
[+]

Ficus carica and Sizigium cumini regulate glucose and lipid parameters in high-fat diet and streptozocin-induced rats.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Diabetes Res. 2020 ;2020:6745873. Epub 2020 Oct 28. PMID: 33178838
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Fig, Plum
Diseases : Diabetes Mellitus: Type 2, High Fat Diet, Obesity
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Malondialdehyde Down-regulation
[+]

Ficus carica aqueous extract alleviates delayed gastric emptying and recovers ulcerative colitis-enhanced acute functional gastrointestinal disorders.Jun 01, 2018

Pubmed Data : J Ethnopharmacol. 2018 Jun 2 ;224:242-249. Epub 2018 Jun 2. PMID: 29870788
Article Published Date : Jun 01, 2018
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Ulcerative Colitis
Pharmacological Actions : Antioxidants, Laxative
[+]

Ficus carica L. leaf extract is effective in preventing gentamicin induced functional and structural changes in kidney of albino mice.Mar 31, 2015

Pubmed Data : J Ayub Med Coll Abbottabad. 2015 Apr-Jun;27(2):398-401. PMID: 26411127
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Chemotherapy-Induced Toxicity: Gentamicin
Pharmacological Actions : Renoprotective
Additional Keywords : Plant Extracts
[+]

Ficus carica latex: possible chemo-preventive, apoptotic activity and safety assessment.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Pharm Res. 2020 ;19(3):231-240. PMID: 33680025
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Chemopreventive
[+]

Ficus carica leaf extracts can be used for male infertility treatment caused by formaldehyde exposure.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:2539127. Epub 2016 Jan 19. PMID: 26904140
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Formaldehyde Toxicity, Infertility: Male
Pharmacological Actions : Cytoprotective
Additional Keywords : Plant Extracts
Problem Substances : Formaldehyde
[+]

Ficus carica leaves extract inhibited pancreatic β-cell apoptosis.Nov 27, 2019

Pubmed Data : Biomed Pharmacother. 2019 Nov 28 ;122:109689. Epub 2019 Nov 28. PMID: 31786467
Article Published Date : Nov 27, 2019
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Pancreato Protective Agents
[+]

Ficus racemosa exhibits protective effects by reducing complications of diabetic neuropathy with neurodegeneration (DNN).Oct 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Pharmacol. 2015 Nov-Dec;47(6):610-5. PMID: 26729951
Article Published Date : Oct 31, 2015
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Diabetic Complications, Diabetic Neuropathy
Pharmacological Actions : Hypoglycemic Agents, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Ficus recemosa bark extract attenuates diabetic complications and oxidative stress Feb 09, 2016

Pubmed Data : Pharm Biol. 2016 Feb 10:1-10. Epub 2016 Feb 10. PMID: 26864816
Article Published Date : Feb 09, 2016
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Cardiomyopathy, Diabetic Complications, Diabetic Nephropathy, Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
Additional Keywords : Plant Extracts
[+]

Ficusin improved the insulin sensitivity on adipose tissue and it can be used for the treatment of obesity related type 2 diabetes mellitus.Aug 24, 2016

Pubmed Data : Chem Biol Interact. 2016 Aug 25 ;256:85-93. Epub 2016 Jun 24. PMID: 27350165
Article Published Date : Aug 24, 2016
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Hypoglycemic Agents, Insulin Sensitizers
[+]

Fig extract and extra virgin olive oil have a powerful antioxidant and many protective effects against cardiac and renal toxicity induced by 5-FU.Sep 17, 2020

Pubmed Data : Environ Sci Pollut Res Int. 2020 Sep 18. Epub 2020 Sep 18. PMID: 32946057
Article Published Date : Sep 17, 2020
Study Type : Animal Study
Additional Links
Substances : Fig, Olive Oil
Diseases : Chemotherapy-Induced Toxicity: 5-fluorouracil
Pharmacological Actions : Cardioprotective, Chemoprotective Agents, Renoprotective
Additional Keywords : Natural Substance Synergy
[+]

Fig fruit has antioxidant and immunostimulatory properties. Jun 01, 2009

Pubmed Data : Plant Foods Hum Nutr. 2009 Jun;64(2):167-73. PMID: 19466553
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Fig, Flavonoids
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Immunomodulatory
Additional Keywords : Plant Extracts
[+]

Fig latex could decrease tumor growth without having any adverse effect on hematological and histological factors.Jun 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2018 Jul-Aug;8(4):286-295. PMID: 30377588
Article Published Date : Jun 30, 2018
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Breast Cancer: Chemically-Induced
Pharmacological Actions : Antiproliferative , Chemopreventive
[+]

Fig leaf tea suppresses allergy by acceleration disassembly of IgE-receptor complexes.Jan 26, 2020

Pubmed Data : Biosci Biotechnol Biochem. 2020 Jan 27:1-10. Epub 2020 Jan 27. PMID: 31987005
Article Published Date : Jan 26, 2020
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Allergies, Atopic Dermatitis, IgE-Mediated Hypersensitivity
Pharmacological Actions : Anti-Allergic Agents, Immunomodulatory
[+]

Fig leaves exerted significant effects on carbohydrate metabolism enzymes with promising hypoglycemic and hypolipidemic activities in T2D rats.Nov 30, 2017

Pubmed Data : Pharm Biol. 2017 Dec ;55(1):1074-1081. PMID: 28193094
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Plant Extracts
[+]

Figs is a potential herbal adjuvant to phenytoin for improved management of epilepsy and associated behavioral comorbidities.Nov 30, 2014

Pubmed Data : Epilepsy Behav. 2014 Dec ;41:171-8. Epub 2014 Oct 25. PMID: 25461211
Article Published Date : Nov 30, 2014
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Epilepsy
Pharmacological Actions : Antioxidants
Additional Keywords : Dose Response, Plant Extracts
[+]

Gold nanoparticles enhanced the anti-oxidative properties of the Fig extract in targeting kidney damage by cisplatin. Nov 30, 2019

Pubmed Data : Colloids Surf B Biointerfaces. 2019 Dec 1 ;184:110465. Epub 2019 Sep 12. PMID: 31546222
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Fig, Gold (nanoparticles)
Diseases : Chemotherapy-Induced Kidney Damage, Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Antioxidants, Chemoprotective Agents, Renoprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Hepatotoxicity and renal toxicity induced by gamma-radiation and the modulatory protective effect of Ficus carica.May 14, 2019

Pubmed Data : Res Vet Sci. 2019 May 15 ;125:24-35. Epub 2019 May 15. PMID: 31125819
Article Published Date : May 14, 2019
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Radiation
Pharmacological Actions : Hepatoprotective, Renoprotective
Anti Therapeutic Actions : Radation Exposure: Low-Dose
[+]

Morin alleviates vincristine-induced neuropathic pain. Jul 31, 2019

Pubmed Data : Cell Mol Neurobiol. 2019 Aug ;39(6):799-808. Epub 2019 Apr 22. PMID: 31011938
Article Published Date : Jul 31, 2019
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Chemotherapy-Induced Toxicity: Vincristine, Neuropathic Pain
Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor
[+]

Protective effects of Ficus carica seed oil on ischemia and reperfusion injury in a rat model of acute mesenteric ischemia.Jun 30, 2021

Pubmed Data : Ulus Travma Acil Cerrahi Derg. 2021 Jul ;27(4):402-409. PMID: 34213002
Article Published Date : Jun 30, 2021
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Quince and fig may increase the therapeutic index of doxorubicin.May 31, 2017

Pubmed Data : Drug Res (Stuttg). 2017 Jun ;67(6):358-365. Epub 2017 Mar 20. PMID: 28320040
Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Substances : Fig, Quince
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Cardioprotective, Chemoprotective Agents, Glutathione Upregulation
Additional Keywords : Plant Extracts
[+]

Tebuconazole-induced toxicity and the protective effect of Ficus carica extract in Neotropical fruit-eating bats.Feb 14, 2021

Pubmed Data : Chemosphere. 2021 Feb 15 ;275:129985. Epub 2021 Feb 15. PMID: 33640742
Article Published Date : Feb 14, 2021
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Pesticide Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Pesticides
[+]

The effects of Ficus carica on male and female reproductive capabilities.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:1799431. Epub 2022 Oct 22. PMID: 36317103
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Infertility
Pharmacological Actions : Fertility Agents
[+]

These results support Ficus carica and oligosaccharides potential anticonvulsant-activity.Sep 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2019 Oct ;9(4):263-270. Epub 2018 Sep 28. PMID: 31453121
Article Published Date : Sep 30, 2019
Study Type : Animal Study
Additional Links
Substances : Fig, Oligosaccharides
Diseases : Seizures: Convulsive
Pharmacological Actions : Anticonvulsants
[+]

This study provides evidence that morin may have anticancer effects against metastatic breast cancer. Sep 30, 2014

Pubmed Data : Int J Oncol. 2014 Oct ;45(4):1629-37. Epub 2014 Jul 4. PMID: 24993541
Article Published Date : Sep 30, 2014
Study Type : Animal Study
Additional Links
Substances : Fig, Flavonoids, Mulberry
Diseases : Breast Cancer, Breast Cancer: Triple Negative , Cancer Metastasis
Pharmacological Actions : Anti-metastatic, Antineoplastic Agents, Antiproliferative , Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Plant Extracts
[+]

Tunisian Ficus carica has a significant hypocholesterolemic effect and antioxidant activity in HFD-fed rats.May 31, 2016

Pubmed Data : Plant Foods Hum Nutr. 2016 Jun ;71(2):183-9. PMID: 27086310
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : High Fat Diet, Hyperlipidemia
Pharmacological Actions : Anticholesteremic Agents
Additional Keywords : Plant Extracts
[+]

In vitro antioxidant activity of Ficus carica L. latex from 18 different cultivars.Jul 01, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2020 Jul 2 ;10(1):10852. Epub 2020 Jul 2. PMID: 32616768
Article Published Date : Jul 01, 2020
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

A water extract from jelly fig seed residues exerted anti-proliferative and apoptotic effects on colorectal cancer cells.Sep 09, 2015

Pubmed Data : Technol Health Care. 2015 Sep 10. Epub 2015 Sep 10. PMID: 26409550
Article Published Date : Sep 09, 2015
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Colorectal Cancer
Pharmacological Actions : Apoptotic, Cell cycle arrest
Additional Keywords : Dose Response, Plant Extracts
[+]

Alkaloids in F. septica have anticancer activity on T47D breast cancer cells.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(16):7337-42. PMID: 26514534
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Breast Cancer
Pharmacological Actions : Cytotoxic
Additional Keywords : Plant Extracts
[+]

An extract from Ficus carica ccell cultures works as an anti-stress ingredient for the skin.Mar 24, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2021 Mar 25 ;10(4). Epub 2021 Mar 25. PMID: 33806157
Article Published Date : Mar 24, 2021
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation
[+]

An herbal mixture could afford be an excellent natural candidate to combat oxidative stress and counteract hepatic toxins.Sep 11, 2017

Pubmed Data : Chem Biodivers. 2017 Sep 12. Epub 2017 Sep 12. PMID: 28898531
Article Published Date : Sep 11, 2017
Study Type : In Vitro Study
Additional Links
Substances : Artichoke, Fig, Mulberry
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective
Additional Keywords : Natural Substance Synergy
[+]

Anti-inflammatory and antiproliferative prenylated isoflavone derivatives from the fruits of Ficus carica.Apr 21, 2019

Pubmed Data : J Agric Food Chem. 2019 Apr 22. Epub 2019 Apr 22. PMID: 30973720
Article Published Date : Apr 21, 2019
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Cancers: All, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative
Additional Keywords : Natural Substances Versus Drugs
[+]

Anti-inflammatory phenylpropanoids and phenolics from Ficus hirta Vahl.Aug 31, 2017

Pubmed Data : Fitoterapia. 2017 Sep ;121:229-234. Epub 2017 Aug 4. PMID: 28782581
Article Published Date : Aug 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

Anticancer activity of methanol extract of Ficus carica leaves and fruits against proliferation, apoptosis, and necrosis in Huh7it cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Inform. 2019 ;18:1176935119842576. Epub 2019 Apr 19. PMID: 31037025
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Antitumoral activity of Ficus carica L. on colorectal cancer cell lines.Jul 30, 2019

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2019 Jul 31 ;65(6):6-11. Epub 2019 Jul 31. PMID: 31472041
Article Published Date : Jul 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Plant Extracts
[+]

Autophagy is involved in Ficus carica fruit extract-induced anti-tumor effects on pancreatic cancer.May 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 Jun ;150:112966. Epub 2022 Apr 12. PMID: 35427822
Article Published Date : May 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Comparative anticancer activities of Ficus carica and Ficus salicifolia latex in MDA-MB-231 cells.May 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi J Biol Sci. 2021 Jun ;28(6):3225-3234. Epub 2021 Feb 24. PMID: 34121859
Article Published Date : May 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Cytotoxic
[+]

Cytotoxicity of Ficus crocata extract on cervical cancer cells and protective effect against hydrogen peroxide-induced oxidative stress.Jan 18, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Plants (Basel). 2021 Jan 19 ;10(1). Epub 2021 Jan 19. PMID: 33478134
Article Published Date : Jan 18, 2021
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Cervical Cancer, Hydrogen Peroxide Induced Toxicity
Pharmacological Actions : Antioxidants, Cytotoxic
[+]

Extracts and components of Ficus carica leaves suppress survival, cell cycle, and migration of triple-negative breast cancer MDA-MB-231 cells.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Onco Targets Ther. 2018 ;11:4377-4386. Epub 2018 Jul 27. PMID: 30100743
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Extracts of Ficus carica and Perilla frutescens have potential for attenuating pathogens.Dec 31, 2013

Pubmed Data : Chemotherapy. 2014 ;60(5-6):379-83. Epub 2015 Oct 24. PMID: 26496663
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Fig, Perilla
Diseases : Gram-Negative Bacterial Infections, Pseudomonas aeruginosa
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Gene Expression Regulation, Multidrug Resistance, Plant Extracts
[+]

Extracts of the fruit of F. carica may have potential anti-diabetic and anti-obesogenic agents.Dec 31, 2017

Pubmed Data : J Food Drug Anal. 2018 Jan ;26(1):201-210. Epub 2017 Apr 22. PMID: 29389556
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Diabetes Mellitus: Type 2, Obesity
Pharmacological Actions : Alpha-amylase inhibitor, Alpha-glucosidase inhibitor
Additional Keywords : Anti-Obesity Agents
[+]

F. religiosa L. is endowed with antiviral activity against respiratory syncytial virus and human rhinovirus in vitro.Oct 30, 2015

Pubmed Data : J Ethnopharmacol. 2015 Oct 31. Epub 2015 Oct 31. PMID: 26528588
Article Published Date : Oct 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Asthma, Respiratory Syncytial Virus Infections, Rhinovirus Infection
Pharmacological Actions : Antiviral Agents
Additional Keywords : Ayurveda, Plant Extracts
[+]

Ficus carica latex prevents invasion through induction of let-7d expression in GBM cell lines.Feb 28, 2015

Pubmed Data : Cell Mol Neurobiol. 2015 Mar ;35(2):175-87. Epub 2014 Sep 12. PMID: 25212824
Article Published Date : Feb 28, 2015
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Cancer Metastasis, Glioblastoma
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Fig leaf extract has antibacterial effect on E. faecalis.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Vet World. 2018 Mar ;11(3):342-347. Epub 2018 Mar 20. PMID: 29657427
Article Published Date : Feb 28, 2018
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Enterococcus Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

Hairy fig extract had significant antioxidant and antifungal activities and could be used for the preservation of agricultural products.Jan 14, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomedicines. 2020 Jan 15 ;8(1). Epub 2020 Jan 15. PMID: 31952281
Article Published Date : Jan 14, 2020
Study Type : Plant Study
Additional Links
Substances : Fig
Diseases : Oxidative Stress
Pharmacological Actions : Antifungal Agents, Antioxidants
Additional Keywords : Plant Extracts
[+]

In vitro pro-apoptotic and anti-migratory effects of Ficus deltoidea plant extracts on the human prostate cancer cell lines PC3.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:895. Epub 2017 Dec 12. PMID: 29326585
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Prostate Cancer
Pharmacological Actions : Anti-metastatic, Apoptotic
Additional Keywords : Plant Extracts
[+]

Influence of extraction solvents on the polyphenol contents, compositions, and antioxidant capacities of fig seeds.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : An Acad Bras Cienc. 2021 ;93(1):e20190526. Epub 2021 Apr 16. PMID: 33886699
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Fig, Polyphenols
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Inhibitory effects of Ficus carica and Olea europaea on pro-inflammatory cytokines.Feb 28, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2022 Mar ;25(3):268-275. PMID: 35656183
Article Published Date : Feb 28, 2022
Study Type : Review
Additional Links
Substances : Fig, Olive
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Phytochemical screening, antioxidant activity and inhibitory potential of Ficus carica and Olea europaea leaves.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Bioinformation. 2019 ;15(3):226-232. Epub 2019 Mar 15. PMID: 31354199
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Fig, Olive
Diseases : Cancers: All, Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Polypeptides from jelly fig inhibits the expression of human HBsAg in host cells without toxic effects on normal primary hepatocytes.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2013 ;2013:434823. Epub 2013 Nov 4. PMID: 24302965
Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Hepatitis B
Pharmacological Actions : Antiviral Agents, Prophylactic Agents
Additional Keywords : Dose Response
[+]

Structural characterization and immunomodulatory activity of a novel polysaccharide from Ficus carica.Jul 16, 2018

Pubmed Data : Food Funct. 2018 Jul 17 ;9(7):3930-3943. PMID: 29974087
Article Published Date : Jul 16, 2018
Study Type : In Vitro Study
Additional Links
Substances : Fig
Pharmacological Actions : Immunomodulatory
Additional Keywords : Polysaccharides
[+]

Study of synergistic effects of Ficus Carica leaves extract mediated chemo-photodynamic therapy on rhabdomyosarcoma cells.Nov 30, 2021

Pubmed Data : Photodiagnosis Photodyn Ther. 2021 Dec ;36:102565. Epub 2021 Oct 3. PMID: 34614426
Article Published Date : Nov 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : Fig
Diseases : Rhabdomyosarcoma
Therapeutic Actions : Photodynamic therapy
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Plant Extracts
[+]

Terminalia chebula and Ficus racemosa controlled virulence factors produced by multiple drug resistant Pseudomonas aeruginosa.Aug 12, 2020

Pubmed Data : Microb Pathog. 2020 Aug 13:104412. Epub 2020 Aug 13. PMID: 32798672
Article Published Date : Aug 12, 2020
Study Type : In Vitro Study
Additional Links
Substances : Fig, Terminalia chebula
Diseases : Infection: Antibiotic Resistant, Pseudomonas aeruginosa
Pharmacological Actions : Anti-Bacterial Agents
[+]

This review summarizes the antidiabetic potentials of the genus Ficus.Jan 02, 2018

Pubmed Data : J Ethnopharmacol. 2018 Jan 3. Epub 2018 Jan 3. PMID: 29305899
Article Published Date : Jan 02, 2018
Study Type : Review
Additional Links
Substances : Fig
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
[+]

This study further confirms the traditional role of Ficus benjamina plant in the treatment of malaria which may be attributed to ursolic acid and lupeol.Jan 01, 2019

Pubmed Data : Nat Prod Res. 2019 Jan 2:1-4. Epub 2019 Jan 2. PMID: 30600705
Article Published Date : Jan 01, 2019
Study Type : In Vitro Study
Additional Links
Substances : Fig, Lupeol, Ursolic Acid
Diseases : Malaria
Pharmacological Actions : Antimalarials

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