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Flavonoids
Views 7583
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366 Diseases Researched for Flavonoids
Name
AC
CK
Focus
Cardiovascular Diseases
27
173
Oxidative Stress
81
170
Hypertension
20
151
Inflammation
67
135
Endothelial Dysfunction
17
92
Colorectal Cancer
15
86
Breast Cancer
33
79
Cholesterol: Oxidation
13
61
Lipopolysaccharide-Induced Toxicity
32
50
Obesity
18
48
Diabetes Mellitus: Type 2
14
46
Arteriosclerosis
7
44
Cognitive Decline/Dysfunction
6
44
Lung Cancer
21
44
Liver Cancer
29
43
Cancers: All
30
41
Stroke
5
41
Depression
14
40
HDL: Low
4
40
Hemorrhoids
4
40
Radiation Induced Illness
13
40
Alzheimer's Disease
22
39
Aging
13
37
DNA damage
14
37
Diabetes Mellitus: Type 2: Prevention
4
33
Coronary Artery Disease
5
32
Thrombosis
4
31
All-Cause Mortality
2
30
Allergic Rhinitis
3
30
Cardiac Mortality
2
30
Cardiovascular Disease: Prevention
3
30
Smoking
3
30
Parkinson's Disease
15
29
Aging: Brain
6
28
Atherosclerosis
9
28
Lipid Peroxidation
18
28
Prostate Cancer
15
28
Colon Cancer
21
25
Aging Skin
5
24
C-Reactive Protein
4
24
Clotting
4
23
Cholesterol: LDL/HDL ratio
3
22
Glaucoma
2
22
Chemically-Induced Liver Damage
12
21
Esophageal Cancer
3
21
Neurodegenerative Diseases
15
21
Athletic Performance: Recovery
2
20
Cancer Mortality
1
20
Chronic Disease
2
20
Deep Vein Thrombosis
2
20
Diabetes: Cardiovascular Illness
2
20
Ocular Hypertension
1
20
Pancreatic Cancer
7
20
Prehypertension
1
20
Rectal Cancer
1
20
Rheumatoid Arthritis
7
19
Insulin Resistance
6
18
Colorectal Cancer: Prevention
3
17
Hypercholesterolemia
5
17
Hyperglycemia
13
17
Myocardial Infarction
5
17
Squamous cell carcinoma
6
17
Asthma
5
16
Hyperlipidemia
9
16
Ovarian Cancer
6
16
Cancer Metastasis
12
15
Diabetic Complications
10
15
Heart Failure
4
15
Brain Inflammation
10
14
Coronavirus Infection
13
14
Hyperuricemia
3
14
Metabolic Syndrome X
3
14
Pesticide Toxicity
3
13
Sunburn
3
13
Arsenic Poisoning
2
12
Bladder Cancer
3
12
Cancers: Drug Resistant
10
12
Cataract
2
12
Helicobacter Pylori Infection
3
12
Menopausal Syndrome
2
12
Osteoporosis
7
12
Pulmonary Diseases
2
12
Cerebral Ischemia
6
11
Chemotherapy-Induced Toxicity: Cisplatin
6
11
Gallbladder Cancer
2
11
Gout
2
11
High Cholesterol
2
11
High Fat Diet
6
11
Laryngeal Cancer
2
11
Periodontal Diseases
2
11
Skin Diseases: Photo-Aging
2
11
Ultraviolet Radiation Induced Damage
9
11
Aflatoxicosis
1
10
Aphthous Ulcer
1
10
Athletic Performance
1
10
Bile Duct Cancer
1
10
Bladder Degeneration
1
10
Blood Platelet Disorders
1
10
Bone Fractures
1
10
Brain Edema
1
10
Cervical Cancer
10
10
Chemotherapy
1
10
Chronic Obstructive Pulmonary Disease
1
10
Climacteric
1
10
Common Cold
1
10
Dental Caries
1
10
Depression
1
10
Dystrophic retinal detachment (DRD)
1
10
Edema
1
10
Erectile Dysfunction
1
10
Eye Diseases: Vitreous Disorders
1
10
Head and Neck Cancer
1
10
Heart Disease: Ischemic
1
10
Hematuria
1
10
Jet Lag
1
10
Leg Edema
1
10
Libido: Low
1
10
Macular Degeneration
1
10
Muscular Dystrophies
1
10
Osteoarthritis: Knee
1
10
Periodontal Wound Healing
1
10
Peripheral vitreochoreoretinal dystrophies (PVCRD)
1
10
Post-Thrombotic Syndrome
1
10
Postmenopausal Disorders: Insomnia
1
10
Postoperative Recovery
1
10
Premenstrual syndrome
1
10
Retinal Detachment
1
10
Sexaul Dysfunction
1
10
Thromboembolism
1
10
Tinnitus
1
10
Venous Thrombosis
1
10
Vericose Veins: Bladder
1
10
Wrinkles
1
10
Alcohol Toxicity
5
9
Brain Ischemia
7
9
Melanoma
7
9
Arthritis
4
8
Carcinoma: Non-Small-Cell Lung
7
8
Colitis
5
8
Coronavirus Disease
7
8
Diabetes Mellitus: Type 1
5
8
Liver Damage
5
8
Oral Cancer
6
8
Advanced Glycation End products (AGE)
5
7
Breast Cancer: Triple Negative
5
7
Gastric Ulcer
4
7
Liver Cancer: Prevention
2
7
Liver Fibrosis
4
7
Memory Disorders
4
7
Nonalcoholic fatty liver disease (NAFLD)
4
7
Breast Cancer: Metastatic
3
6
Glioma
4
6
HIV Infections
6
6
Hydrogen Peroxide Induced Toxicity
6
6
Infertility: Male
3
6
Inflammatory Bowel Diseases
3
6
Lung Injury: Acute
3
6
Mycobacterium tuberculosis
2
6
Myocardial Ischemia
3
6
Neuroblastoma
4
6
Ulcerative Colitis
3
6
Aging: Immunosenecence
3
5
Blastocystis hominis infections
1
5
Cancers: Multi-Drug Resistant
5
5
Diabetes: Oxidative Stress
3
5
Dyslipidemias
3
5
Gastric Cancer
5
5
Glioblastoma
5
5
Osteoarthritis
3
5
Osteosarcoma
5
5
Psoriasis
4
5
Staphylococcus aureus infection
5
5
Tumors
4
5
Acetaminophen (Tylenol) Toxicity
2
4
Alcoholic Liver Disease
2
4
Allergies
3
4
Anaphylaxis
2
4
Anxiety
2
4
Benzo[a]pyrene-induced Toxicity
3
4
Cardiomyopathy
2
4
Chemotherapy-Induced Kidney Damage
2
4
Diabetic Nephropathy
3
4
Escherichia coli Infections
4
4
Fatty Liver
2
4
Hypoxia
3
4
IgE-Mediated Hypersensitivity
2
4
Immune Disorders: Low Immune Function
2
4
Influenza
3
4
Liver Damage: Drug-Induced
2
4
Liver Injury: Ischemia/reperfusion
2
4
Lymphoma
3
4
Promyelocytic leukemia
4
4
Seizures
2
4
Brain Injury: Traumatic
2
3
Brain: Oxidative Stress
2
3
Chemotherapy and Radiation Toxicity
3
3
Cholera
2
3
Dementia
3
3
Dengue
2
3
Diabetes: Cataract
2
3
Dioxin Toxicity
2
3
Eye Diseases
2
3
Kidney Cancer
3
3
Kidney Damage: Drug-Induced
2
3
Liver Disease
2
3
MRSA
2
3
Periodontitis
2
3
Scars
2
3
Severe Acute Respiratory Syndrome
3
3
Skin Cancer
2
3
Snake Bite: Venom Toxicity
2
3
Abdominal Obesity (Midsection Fat)
1
2
Aging: Liver
1
2
Aluminum Toxicity
1
2
Amyotrophic Lateral Sclerosis
2
2
Aspirin-Induced Toxicity
1
2
Atopic Dermatitis
1
2
Autism
1
2
Bacterial Infections
2
2
Bone Diseases
1
2
Brain Injury: Hippocampal Damage
1
2
Brain: Microglial Activation
2
2
Breast Cancer: Lung Metastasis
1
2
Cadmium Poisoning
1
2
Candida Albicans
2
2
Cerebral Vasospasm
1
2
Chemotherapy-Induced Toxicity: Cyclophosphamide
1
2
Chemotherapy-Induced Toxicity: Gentamicin
1
2
Chikungunya Virus
2
2
Cholangiocarcinoma
2
2
Colon Polyps
1
2
Convulsions
1
2
Cystic Fibrosis
2
2
Diabetes: Cognitive Dysfunction
1
2
Diesel Exhaust Particle Toxicity
1
2
Dopamine Deficiency
1
2
Drug-Induced Toxicity: Indomethacin
1
2
Ehrlich carcinoma
1
2
Enterovirus 71
1
2
Estrogen Dominance
2
2
Fatigue: Excercise-Induced
1
2
Fibrosis
1
2
Food Allergies
1
2
Fructose-Induced Toxicity
1
2
Gastrointestinal Diseases
1
2
Giardiasis
2
2
Heat Stroke
1
2
Hepatic Steatosis
1
2
Hepatitis: Lectin-Induced (concanavalin)
1
2
High Fructose Diet
1
2
Hypothyroidism
1
2
IgA Deficiency
1
2
Infertility: Aging Associated
1
2
Infertility: Female
1
2
Intestinal Diseases
1
2
Intestinal Permeability
2
2
Iron Overload
1
2
Irritable Bowel Syndrome
1
2
Ischemia
1
2
Kidney Damage: Chemically-Induced
1
2
Leaky Gut Syndrome
2
2
Learning disorders
1
2
Leukemia
2
2
Leukemia: Acute myelogenous leukemia (AML)
1
2
Leukemia: Chronic myelogenous leukemia (CML)
1
2
Liver Cirrhosis
1
2
Low Immune Function: Thymus Dysfunction
1
2
Mercury Poisoning
1
2
Mouse Endogenous Retroviruses
1
2
Muscle Damage: Exercise-Induced
1
2
Myasthenia Gravis
1
2
Myocardial Fibrosis
1
2
NSAID-induced toxicity
1
2
Nasopharyngeal Cancer
2
2
Ovariectomy Associated Adverse Changes
1
2
Pesticide-Induced Toxicity: Organophosphates
1
2
Petroleum Exposure And Toxicity
1
2
Prenatal Chemical Exposures
1
2
Prenatal Nutrition: Health of the Offspring
1
2
Prostatic Hyperplasia: Benign
1
2
Pulmonary Fibrosis
1
2
Radiation
2
2
Radiation Induced Illness: Bone Marrow
1
2
Renal Fibrosis
1
2
Sepsis
1
2
Sinusitis
1
2
Skin Cancer: Prevention
1
2
Sperm Quality: Low
1
2
Systemic Lupus Erythematosus
1
2
Thyroid Cancer
2
2
Wound Healing
1
2
Actinic Keratosis
1
1
Acute lymphoblastic leukemia (ALL)
1
1
Allergic Airway Diseases
1
1
Amyloidosis
1
1
Anemia: Hemolytic
1
1
Animal Diseases: Canine Distemper Virus
1
1
Aspergillosis
1
1
Bacillus subtilis infections
1
1
Cancers
1
1
Candida Infection
1
1
Chemotherapy-Induced Toxicity: Bleomycin
1
1
Chemotherapy-Induced Toxicity: Doxorubicin
1
1
Chronic Myeloid Leukemia
1
1
Clostridium Infections
1
1
Copper Toxicity
1
1
Coronaviridae Infections
1
1
Cryptosporidiosis
1
1
Cytomegalovirus Infections
1
1
Diabetes Mellitus: Type 1: Prevention
1
1
Diarrhea
1
1
Dry Eye Syndromes
1
1
Endometrial Cancer
1
1
Epstein-Barr Virus Infections
1
1
Excitotoxicity
1
1
Fatigue
1
1
Glucosephosphate Dehydrogenase Deficiency
1
1
HSV-1
1
1
HSV-2
1
1
Hepatitis Viruses
1
1
High Homocysteine
1
1
Huntington Disease
1
1
Hyperinsulinism
1
1
Hypertension: Pulmonary
1
1
Influenza in Swine
1
1
Kidney Damage
1
1
Klebsiella Infections
1
1
Leishmaniasis
1
1
Leukemia: Monocytic
1
1
Liver Diseases
1
1
Lymphoma: Non-Hodgkin
1
1
Lymphoma: T-cell
1
1
Malaria
1
1
Malignant Melanoma
1
1
Micrococcus luteus infections
1
1
Neurological Conditions
1
1
Neuropathic Pain
1
1
Non-Small-Cell Lung Carcinoma
1
1
Otitis media
1
1
Photooxidative Stress
1
1
Phthalate Toxicity
1
1
Protozoan Infections
1
1
Pseudomonas aeruginosa
1
1
Psychiatric Disorders
1
1
Radiation-Induced Illness: Cesium-137 Exposure
1
1
Respiratory Infections
1
1
Retinoblastoma
1
1
Rhinovirus Infection
1
1
Salmonella Infections
1
1
Sarcopenia
1
1
Schizophrenia
1
1
Seizures: Drug-Induced
1
1
Simian virus 40 (SV40)
1
1
Staphylococcal Infections
1
1
Staphylococcus aureus: Methicillin-resistant (MRSA)
1
1
Staphylococcus epidermidis
1
1
Steptococcus Mutans Infections
1
1
Sugar (Sucrose) Toxicity
1
1
Swine Flu Associated Virus
1
1
Tertiary butyl hydroperoxide toxicity
1
1
Testicular Cancer
1
1
Tongue Cancer
1
1
Triglycerides: Elevated
1
1
Vibrio Infections
1
1
Weight Problems
1
1
disease
1
1
164 Pharmacological Actions Researched for Flavonoids
Name
AC
CK
Focus
Antioxidants
224
469
Anti-Inflammatory Agents
139
241
Chemopreventive
53
216
Neuroprotective Agents
61
149
Apoptotic
124
144
Antiproliferative
116
140
Tumor Necrosis Factor (TNF) Alpha Inhibitor
51
94
Cardioprotective
25
92
NF-kappaB Inhibitor
52
92
Interleukin-1 beta downregulation
33
68
Hepatoprotective
35
63
Interleukin-6 Downregulation
38
63
Platelet Aggregation Inhibitors
7
62
Cyclooxygenase 2 Inhibitors
30
60
Anti-Apoptotic
33
58
Cell cycle arrest
43
58
Antineoplastic Agents
36
52
Hypoglycemic Agents
24
51
Anticarcinogenic Agents
26
46
Hypotensive
2
40
Anti-metastatic
29
39
Antidepressive Agents
13
39
Nrf2 activation
18
38
Antihypertensive Agents
7
35
Radioprotective
16
34
Hypolipidemic
17
27
Analgesics
6
26
Immunomodulatory
14
26
Anticholesteremic Agents
5
25
MicroRNA modulator
5
24
Vasodilator Agents
4
23
Enzyme Inhibitors
18
22
Antiviral Agents
20
21
Chemotherapeutic
19
21
Anti-Bacterial Agents
18
19
Chemosensitizer
16
19
Tumor Suppressor Protein p53 Upregulation
14
18
Anti-Allergic Agents
4
15
Renoprotective
9
15
Anti-Fibrotic
8
14
Matrix metalloproteinase-3 (MMP-3) inhibitor
4
14
Chemoprotective Agents
7
13
Osteoprotective
8
13
Malondialdehyde Down-regulation
6
12
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
2
12
Matrix metalloproteinase-2 (MMP-2) inhibitor
9
12
Photoprotective
9
12
Alpha-glucosidase inhibitor
10
11
Anti-Platelet
2
11
Matrix metalloproteinase-9 (MMP-9) inhibitor
9
11
Nitric Oxide Enhancer
2
11
Vasoprotective
2
11
Anti Inflammatory
2
10
Anti-thrombotic
1
10
Calcium Channel Blockers
1
10
Cardiovascular Agents
1
10
Detoxifier
1
10
Gastroprotective
6
10
Prophylactic Agents
1
10
Gastrointestinal Agents
6
9
Anti-Ulcer Agents
4
8
Heme oxygenase-1 up-regulation
5
8
Nitric Oxide Inhibitor
5
8
Anti-Angiogenic
5
7
Bcl-2 protein down-regulation
5
7
Brain-derived neurotrophic factor modulator
4
7
Antimicrobial
5
6
Antiparasitic Agents
2
6
Glutathione Upregulation
2
6
Interleukin-8 downregulation
4
6
Superoxide Dismutase Up-regulation
4
6
Vascular Endothelial Growth Factor Inhibitors
4
6
Anticonvulsants
3
5
Antifungal Agents
5
5
Autophagy Inhibitors
4
5
Autophagy Up-regulation
5
5
Cyclooxygenase 1 Inhibitor
3
5
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor
1
5
Interleukin-10 downregulation
3
5
Matrix metalloproteinase-1 (MMP-1) inhibitor
4
5
Postaglandin PGE2 downregulation
4
5
Anti-Anxiety Agents
2
4
Anti-Glycation Agents
3
4
Antimutagenic Agents
4
4
Genoprotective
3
4
Interferon Gamma Reducer
2
4
Interleukin-2 Downregulation
2
4
Phase II Detoxification Enzyme Inducer
2
4
Angiogenesis Inhibitors
2
3
Anti-HIV Agents
3
3
Anti-atherogenic
3
3
Antinoceceptive
2
3
Cytoprotective
2
3
Iron Chelating Agents
2
3
STAT3 Inhibitor
3
3
5-Lipoxygenase Inhibitor
2
2
Aldose reductase inhibitor
1
2
Alpha-amylase inhibitor
2
2
Anti-Tumor
1
2
Antidiarrheals
1
2
Appetite Depressants
1
2
Bcl-xL down-regulation
1
2
Caspase-3 Activation
2
2
Catalase Up-Regulation
1
2
Cyclooxygenase Inhibitors
1
2
Cytotoxic
2
2
Dopaminergic
1
2
Enzyme Inhibitors: Pancreatic Lipase
1
2
Fertility Agents: Male
1
2
Heme oxygenase-1 inducer
1
2
Immunomodulatory: Th17 downregulation
1
2
Immunostimulatory
2
2
Interleukin-12 downregulation
1
2
Interleukin-17 downregulation
1
2
Interleukin-18 down-regulation
1
2
Interleukin-4 downregulation
2
2
Interleukin-5 downregulation
2
2
Neurominidase Inhibitor
2
2
Proteasome Inhibitors
2
2
Regenerative
2
2
Vascular Cell Adhesion Molecule-1 Inhibitor
2
2
Vascular Endothelial Growth Factor A Inhibitor
1
2
Wnt/β-catenin signaling pathway modulation
2
2
Acetylcholinesterase Inhibitor
1
1
Angiotensin-Converting Enzyme Inhibitors
1
1
Anti-Asthmatic Agents
1
1
Anti-Estrogenic
1
1
Antigiardial agents
1
1
Antioxidant
1
1
Antioxidant Effects
1
1
Antiprotozoal Agents
1
1
Aromatase Inhibitors
1
1
Bax/Bcl2 Ratio: Decrease
1
1
Chondroprotective
1
1
Cytotoxicity
1
1
DNA Repair Up-regulation
1
1
E-cadherin down-regulation
1
1
Estrogen Receptor Agonist
1
1
Expectorants
1
1
Forkhead Transcription Factor Family O (FOXO) Modulator
1
1
Glucagon Like Peptide 1 (GLP-1) Down-Regulation
1
1
Glucagon Like peptide 1 (GLP-1) Up-regulation
1
1
Gluconeogenesis Inhibitor
1
1
Histamine Antagonists
1
1
Histone deacetylase inhibitor
1
1
Hypoxia-inducible factor-1 (HIF-1) inhibitor
1
1
Insulin-releasing
1
1
Leishmanicidal
1
1
Leukotriene Antagonists
1
1
Metal Chelation: Copper
1
1
P-glycoprotein Inhibitors
1
1
P21 Activation
1
1
P38 Mitogen-Activated Protein Kinase Modulator
1
1
Pancreato Protective Agents
1
1
Prostaglandin PGE2 downregulation
1
1
Radiosensitizer
1
1
Sedative effects
1
1
Telomere Protective
1
1
Topoisomerase I inhibitor
1
1
Topoisomerase II Inhibitor
1
1
Transforming growth factor beta (TGF-β) inhibitor
1
1
Transforming growth factor beta (TGF-β) upregulation
1
1
Xanthine oxidase inhibitor
1
1
interleukin-13 down-regulation
1
1
Research Articles
870
Cumulative Knowledge Score
1407
Overall Research Rating
EXCELLENT
View the Evidence:
1994 Abstracts with Flavonoids Research
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[+]
"Dietary flavonoid for preventing colorectal neoplasms."
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Cochrane Database Syst Rev. 2012 ;8:CD009350. Epub 2012 Aug 15. PMID:
22895989
Article Published Date
: Dec 31, 2011
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavonoids
Diseases
:
Colorectal Cancer
[+]
Cocoa products have blood-pressure lowering capacity.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Am J Hypertens. 2010 Jan;23(1):97-103. Epub 2009 Nov 12. PMID:
19910929
Article Published Date
: Jan 01, 2010
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavonoids
Diseases
:
Hypertension
Pharmacological Actions
:
Hypotensive
[+]
Dark chocolate is superior to placebo in reducing systolic hypertension or diastolic prehypertension.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: BMC Med. 2010;8:39. Epub 2010 Jun 28. PMID:
20584271
Article Published Date
: Jan 01, 2010
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavonoids
Diseases
:
Hypertension
,
Prehypertension
Pharmacological Actions
:
Hypotensive
[+]
Flavonoid intake reduces all-cause mortality.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2015 Apr 1. Epub 2015 Apr 1. PMID:
25832340
Article Published Date
: Mar 31, 2015
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavonoids
Diseases
:
All-Cause Mortality
,
Cancer Mortality
,
Cardiac Mortality
[+]
Flavonoids have a promising role in improving visual function in patients with glaucoma and ocular hypertension.
Sep 03, 2015
Click here to read the entire abstract
Pubmed Data
: Graefes Arch Clin Exp Ophthalmol. 2015 Sep 4. Epub 2015 Sep 4. PMID:
26340868
Article Published Date
: Sep 03, 2015
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Cocoa
,
Flavonoids
,
Green Tea
,
Red Wine Extract
Diseases
:
Glaucoma
,
Ocular Hypertension
[+]
High intake of flavonols may reduce the risk of colon cancer and high intake of flavones may reduce the risk of rectal cancer.
Jul 22, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2018 Jul 23 ;10(7). Epub 2018 Jul 23. PMID:
30041489
Article Published Date
: Jul 22, 2018
Study Type
: Meta Analysis
Additional Links
Substances
:
Apigenin
,
Flavonoids
,
Quercetin
Diseases
:
Colorectal Cancer
,
Rectal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Higher intakes of total flavonoids and subclasses are associated with lower risk of T2DM.
Apr 30, 2018
Click here to read the entire abstract
Pubmed Data
: Medicine (Baltimore). 2018 May ;97(19):e0686. PMID:
29742713
Article Published Date
: Apr 30, 2018
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavan-3-ols
,
Flavonoids
,
Isoflavones
Diseases
:
Diabetes Mellitus: Type 2: Prevention
Additional Keywords
:
Risk Reduction
[+]
Protective role of baicalin in the dynamic progression of lung injury to idiopathic pulmonary fibrosis.
May 31, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Phytomedicine. 2023 Jun ;114:154777. Epub 2023 Mar 20. PMID:
37018850
Article Published Date
: May 31, 2023
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavonoids
Diseases
:
Pulmonary Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
The present study suggests the intake of flavonols and flavones is associated with a decreased risk of breast cancer.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2013 ;8(1):e54318. Epub 2013 Jan 18. PMID:
23349849
Article Published Date
: Dec 31, 2012
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavonoids
Diseases
:
Breast Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
The present systematic review suggests that the dietary intakes of six classes of flavonoids significantly decrease the risk of cardiovascular diseases.
Jan 13, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2014 Jan 14 ;111(1):1-11. Epub 2013 Aug 16. PMID:
23953879
Article Published Date
: Jan 13, 2014
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Cardiovascular Diseases
Pharmacological Actions
:
Cardioprotective
Additional Keywords
:
Phytotherapy
,
Plant Extracts
,
Proanthocyanidins
[+]
Baicalin modulated β-catenin in the relief of inflammatory factor-induced depression complicated with male infertility.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2022 ;2022:2112359. Epub 2022 Apr 7. PMID:
35432561
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Depression
,
Infertility: Male
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
High polyphenol chocolate is effective in improving the atherosclerotic cholesterol profile in patients with diabetes by increasing HDL cholesterol and improving the cholesterol:HDL ratio.
Nov 01, 2010
Click here to read the entire abstract
Pubmed Data
: Diabet Med. 2010 Nov;27(11):1318-21. PMID:
20968113
Article Published Date
: Nov 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cholesterol: LDL/HDL ratio
,
Diabetes: Cardiovascular Illness
,
HDL: Low
[+]
Plasma polyphenols and antioxidants, oxidative DNA damage and endothelial function in a diet and wine intervention study in humans.
Dec 31, 1998
Click here to read the entire abstract
Pubmed Data
: Drugs Exp Clin Res. 1999 ;25(2-3):133-41. PMID:
10370876
Article Published Date
: Dec 31, 1998
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Red Wine
Diseases
:
Arteriosclerosis
,
DNA damage
,
Endothelial Dysfunction
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
"Kidney function in metabolic syndrome may be improved with Pycnogenol®."
May 31, 2010
Click here to read the entire abstract
Pubmed Data
: Panminerva Med. 2010 Jun ;52(2 Suppl 1):27-32. PMID:
20657531
Article Published Date
: May 31, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Metabolic Syndrome X
Pharmacological Actions
:
Antihypertensive Agents
[+]
A Chinese green tea polyphenol extract has evident anti-plaque effect.
Sep 01, 2000
Click here to read the entire abstract
Pubmed Data
: Zhonghua Kou Qiang Yi Xue Za Zhi. 2000 Sep;35(5):383-4. PMID:
11780252
Article Published Date
: Sep 01, 2000
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
Diseases
:
Dental Caries
[+]
A combination of apigenin and EGCG prevent colorectal cancer recurrence.
Apr 14, 2008
Click here to read the entire abstract
Pubmed Data
: World J Gastroenterol. 2008 Apr 14;14(14):2187-93. PMID:
18407592
Article Published Date
: Apr 14, 2008
Study Type
: Human Study
Additional Links
Substances
:
Apigenin
,
Catechin
,
Flavonoids
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
A combination of diosmin and hesperidin significantly reduces bleeding in patients with acute internal hemorrhoids.
Jun 01, 2005
Click here to read the entire abstract
Pubmed Data
: Clin Ther. 2005 Jun;27(6):746-54. PMID:
16117981
Article Published Date
: Jun 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Diosmin
,
Flavonoids
,
Hesperidin
Diseases
:
Hemorrhoids
[+]
A combination of pine bark extract and nattokinase prevents venous thrombosis in long-haul flights.
Sep 01, 2003
Click here to read the entire abstract
Pubmed Data
: Angiology. 2003 Sep-Oct;54(5):531-9. PMID:
14565628
Article Published Date
: Sep 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Nattokinase
Diseases
:
Deep Vein Thrombosis
,
Thromboembolism
,
Thrombosis
Pharmacological Actions
:
Platelet Aggregation Inhibitors
[+]
A flavonoid supplement improves leg health and reduces fluid retention in premenopausal women.
Jan 01, 2004
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2004 Jan;11(1):11-7. PMID:
14971717
Article Published Date
: Jan 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Premenstrual syndrome
Additional Keywords
:
Oligomeric Procyanidins
,
Water Retention
[+]
A flavonol-rich diet may decrease the risk of advanced adenoma recurrence.
May 31, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2008 Jun ;17(6):1344-53. PMID:
18559549
Article Published Date
: May 31, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
A polyphenol-rich beverage reduces symptoms associated with the common cold.
Oct 01, 2010
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2010 Oct;104(8):1156-64. Epub 2010 May 21. PMID:
20487584
Article Published Date
: Oct 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Common Cold
[+]
A Xanthohumol-rich hop extract diminishes endotoxin-induced activation of TLR4 Signaling in human peripheral blood mononuclear cells.
Oct 20, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2022 Oct 21 ;23(20). Epub 2022 Oct 21. PMID:
36293555
Article Published Date
: Oct 20, 2022
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Hops
,
Xanthohumol
Diseases
:
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
Acute consumption of flavanol-rich cocoa and the reversal of endothelial dysunfction in smokers.
Oct 04, 2005
Click here to read the entire abstract
Pubmed Data
: J Am Coll Cardiol. 2005 Oct 4;46(7):1276-83. PMID:
16198843
Article Published Date
: Oct 04, 2005
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Endothelial Dysfunction
,
Smoking
[+]
Apple peel extract inhibits the growth of Helicobacter pylori, and attenuates damage to the gastric mucosa caused by neutrophils.
Sep 09, 2009
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2009 Sep 9;57(17):7743-9. PMID:
19691323
Article Published Date
: Sep 09, 2009
Study Type
: Human Study
Additional Links
Substances
:
Apples
,
Flavonoids
,
Polyphenols
Diseases
:
Helicobacter Pylori Infection
Additional Keywords
:
Plant Extracts
,
Proanthocyanidins
[+]
Association between dietary intake of flavonoids and hyperuricemia.
Jun 23, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Public Health. 2023 Jun 24 ;23(1):1227. Epub 2023 Jun 24. PMID:
37355562
Article Published Date
: Jun 23, 2023
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Hyperuricemia
Pharmacological Actions
:
Uricosuric Agents
[+]
Association of total flavonoid intake with hypo-HDL-cholesterolemia among Korean adults: effect modification by polyunsaturated fatty acid intake.
Jan 09, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2020 Jan 10 ;12(1). Epub 2020 Jan 10. PMID:
31936778
Article Published Date
: Jan 09, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyunsaturated Fatty Acids (PUFAs)
,
Proanthocyanidins
Diseases
:
Hypercholesterolemia
Pharmacological Actions
:
Anticholesteremic Agents
[+]
Auricular acupressure at some specific acupoints can significantly improve the absorption of naringenin and hesperetin in the extracts form C. aurantium L.
Apr 30, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Altern Complement Med. 2008 May ;14(4):423-5. PMID:
18576924
Article Published Date
: Apr 30, 2008
Study Type
: Human Study
Additional Links
Substances
:
Bitter Orange
,
Flavonoids
,
Naringenin
Therapeutic Actions
:
Acupressure: Auricular
Additional Keywords
:
Absorption
[+]
Baicalin capsules combined with α-lipoic acid are effective in treating patients with diabetic peripheral neuropathy.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Transl Res. 2021 ;13(4):2774-2783. Epub 2021 Apr 15. PMID:
34017440
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Alpha-Lipoic Acid
,
Flavonoids
Diseases
:
Peripheral Neuropathies
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Bilberry has anti-inflammatory properties.
Sep 01, 2010
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2010 Sep;49(6):345-55. Epub 2010 Feb 2. PMID:
20119859
Article Published Date
: Sep 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Bilberry
,
Flavonoids
,
Polyphenols
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
NF-kappaB Inhibitor
[+]
Blood pressure is reduced and insulin sensitivity increased in glucose-intolerant, hypertensive subjects after 15 days of consuming high-polyphenol dark chocolate.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2008 Sep;138(9):1671-6. PMID:
18716168
Article Published Date
: Sep 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cardiovascular Diseases
,
Hypertension
,
Insulin Resistance
[+]
Blueberry flavonoid consumption promotes a positive mood and are a possible way to prevent dysphoria and depression.
Feb 19, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Feb 20 ;9(2). Epub 2017 Feb 20. PMID:
28230732
Article Published Date
: Feb 19, 2017
Study Type
: Human Study
Additional Links
Substances
:
Blueberry
,
Flavonoids
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
[+]
Cocoa extract supplementation reduced cardiovascular disease death by 27%.
Mar 15, 2022
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2022 Mar 16. Epub 2022 Mar 16. PMID:
35294962
Article Published Date
: Mar 15, 2022
Study Type
: Human Study
Additional Links
Substances
:
Cocoa
,
Flavonoids
Diseases
:
Cardiac Mortality
Pharmacological Actions
:
Cardioprotective
Additional Keywords
:
Risk Reduction
[+]
Cocoa inhibits LDL oxidation both in vitro and ex vivo.
Apr 06, 1999
Click here to read the entire abstract
Pubmed Data
: Mutat Res. 1999 Apr 6;440(2):181-8. PMID:
11185658
Article Published Date
: Apr 06, 1999
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Arteriosclerosis
,
Cholesterol: Oxidation
Pharmacological Actions
:
Antioxidants
[+]
Cocoa powder and dark chocolate may favorably affect cardiovascular disease risk status by modestly reducing LDL oxidation susceptibility and increasing serum total antioxidant capacity and HDL-cholesterol concentrations.
Nov 01, 2001
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2001 Nov;74(5):596-602. PMID:
11684527
Article Published Date
: Nov 01, 2001
Study Type
: Human Study
Additional Links
Substances
:
Catechin
,
Flavonoids
Diseases
:
Cardiovascular Diseases
,
Cholesterol: Oxidation
,
HDL: Low
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Proanthocyanidins
[+]
Coffee appears to have a beneficial effect on pulmonary function, among non-smokers.
Oct 15, 2010
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2010 Oct 15;127(8):1758-68. PMID:
19372215
Article Published Date
: Oct 15, 2010
Study Type
: Human Study
Additional Links
Substances
:
Coffee
,
Flavonoids
,
Polyphenols
Diseases
:
Pulmonary Diseases
,
Smoking
[+]
Comparison of centella with flavonoids for treatment of symptoms in hemorrhoidal disease and after surgical intervention.
May 13, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2020 May 14 ;10(1):8009. Epub 2020 May 14. PMID:
32409760
Article Published Date
: May 13, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Gotu Kola
Diseases
:
Hemorrhoids
[+]
Consumption of flavanone-rich citrus juice in quantities commonly consumed can acutely enhance blood flow to the brain in healthy young adults.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2016 Dec ;116(12):2160-2168. Epub 2017 Jan 16. PMID:
28091350
Article Published Date
: Nov 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Vitamin C
[+]
Consumption of high flavanol dark chocolate confers modest improvements in cardiovascular function.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: Vascul Pharmacol. 2015 Aug ;71:70-8. Epub 2015 Apr 11. PMID:
25869509
Article Published Date
: Jul 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Chocolate
,
Cocoa
,
Flavonoids
Diseases
:
Cardiovascular Disease: Prevention
,
Cardiovascular Diseases
Pharmacological Actions
:
Cardiovascular Agents
[+]
Consumption of phytochemical-rich foods may prevent the development of hypertension.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Nutr. 2015 Mar ;69(3):392-8. Epub 2014 Nov 12. PMID:
25387902
Article Published Date
: Feb 28, 2015
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Hypertension
Additional Keywords
:
Dietary Modification
,
Plant Extracts
,
Risk Reduction
[+]
Consumptions of citrus fruits, strawberries and grapes were found associated with a lower stroke risk in women.
Jan 28, 2021
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2021 Jan 29:1-8. Epub 2021 Jan 29. PMID:
33509322
Article Published Date
: Jan 28, 2021
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Fruit: All
,
Grape
,
Strawberry
Diseases
:
Stroke
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
Continuous intake of polyphenolic compounds containing cocoa powder reduces LDL oxidative susceptibility and has beneficial effects on plasma HDL-cholesterol concentrations in humans.
Jun 02, 2009
Click here to read the entire abstract
Pubmed Data
: Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):9033-8. Epub 2009 May 18. PMID:
17344491
Article Published Date
: Jun 02, 2009
Study Type
: Human Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Polyphenols
Diseases
:
Cholesterol: Oxidation
,
HDL: Low
Pharmacological Actions
:
Antioxidants
[+]
Dark chocolate consumption increases HDL cholesterol concentration and chocolate fatty acids may inhibit lipid peroxidation in healthy humans.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol.2008 Dec;46(12):3586-92. Epub 2008 Sep 3 PMID:
15454274
Article Published Date
: Dec 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Chocolate
,
Flavonoids
,
Polyphenols
Diseases
:
Cholesterol: LDL/HDL ratio
,
Cholesterol: Oxidation
,
HDL: Low
[+]
Dark chocolate improves coronary vasomotion and reduces platelet reactivity.
Nov 20, 2007
Click here to read the entire abstract
Pubmed Data
: Circulation. 2007 Nov 20;116(21):2376-82. Epub 2007 Nov 5. PMID:
17984375
Article Published Date
: Nov 20, 2007
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Blood Platelet Disorders
,
Clotting
,
Coronary Artery Disease
,
Endothelial Dysfunction
Pharmacological Actions
:
Anti-Platelet
,
Vasodilator Agents
[+]
Dietary flavonoid intake and reduced risk of esophageal squamous cell carcinoma.
Mar 06, 2021
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2021 Mar 7 ;89:111235. Epub 2021 Mar 7. PMID:
33878555
Article Published Date
: Mar 06, 2021
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Esophageal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
Dietary flavonoid intake at midlife and healthy aging in women.
Nov 30, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2014 Dec ;100(6):1489-97. Epub 2014 Oct 29. PMID:
25411284
Article Published Date
: Nov 30, 2014
Study Type
: Human Study
Additional Links
Substances
:
Apple
,
Berries: All
,
Flavonoids
,
Onion
,
Orange
Diseases
:
Aging
,
Cancers: All
,
Cardiovascular Diseases
,
Diabetes Mellitus: Type 2
,
Hypertension
,
Stroke
Additional Keywords
:
Risk Reduction
[+]
Dietary flavonoids improve urinary arsenic elimination among Mexican women.
Jun 30, 2018
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2018 Jul ;55:65-71. Epub 2018 Apr 21. PMID:
29914629
Article Published Date
: Jun 30, 2018
Study Type
: Human Study
Additional Links
Substances
:
Apigenin
,
Flavan-3-ols
,
Flavonoids
Diseases
:
Arsenic Poisoning
Pharmacological Actions
:
Detoxifier
Problem Substances
:
Arsenic
[+]
Flavanols are effective at counteracting mental stress-induced endothelial dysfunction and improving peripheral blood flow during stress.
Mar 26, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2021 Mar 27 ;13(4). Epub 2021 Mar 27. PMID:
33801767
Article Published Date
: Mar 26, 2021
Study Type
: Human Study
Additional Links
Substances
:
Cocoa
,
Flavonoids
Diseases
:
Endothelial Dysfunction
,
Hypertension
Pharmacological Actions
:
Vasoprotective
[+]
Flavanone intake is inversely associated with esophageal cancer risk and may account, with vitamin C, for the protective effect of fruit, especially citrus fruit, on esophageal cancer.
Apr 10, 2000
Click here to read the entire abstract
Pubmed Data
: Arch Intern Med. 2000 Apr 10;160(7):1009-13. PMID:
17192901
Article Published Date
: Apr 10, 2000
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Fruit: All
,
Grapefruit
,
Lemon Juice
,
Orange
,
Vitamin C
Diseases
:
Esophageal Cancer
Additional Keywords
:
Risk Reduction
[+]
Flavonoid antioxidants may have therapeutic value in PVCRD and DRD for the purpose of improving and stabilizing the visual functions and for neuroprotection.
Aug 01, 2009
Click here to read the entire abstract
Pubmed Data
: Inflamm Res. 2009 Aug;58(8):513-21. Epub 2009 Mar 11. PMID:
15384840
Article Published Date
: Aug 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Ginkgo biloba
Diseases
:
Dystrophic retinal detachment (DRD)
,
Eye Diseases: Vitreous Disorders
,
Peripheral vitreochoreoretinal dystrophies (PVCRD)
,
Retinal Detachment
Pharmacological Actions
:
Antioxidants
[+]
Flavonoid consumption may be beneficial for disease prevention.
May 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Diabetes. 2017 May 15 ;7(5):e276. Epub 2017 May 15. PMID:
28504712
Article Published Date
: May 14, 2017
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
C-Reactive Protein
,
Chronic Disease
,
Inflammation
,
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Flavonoid consumption reduces the risk of esophageal cancer.
Jun 01, 2007
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2007 Jun;21(6):501-6. PMID:
19444905
Article Published Date
: Jun 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Esophageal Cancer
Additional Keywords
:
Proanthocyanidins
,
Risk Reduction
[+]
Flavonoid intake and the risk of age-related cataract in China's Heilongjiang Province.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Nutr Res. 2015 ;59:29564. Epub 2015 Dec 11. PMID:
26652740
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Quercetin
Diseases
:
Cataract
Additional Keywords
:
Risk Reduction
[+]
Flavonoid mixture (diosmin, troxerutin, rutin, hesperidin, quercetin) in the treatment of I-III degree hemorroidal disease.
Oct 31, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Colorectal Dis. 2018 Nov ;33(11):1595-1600. Epub 2018 Jun 22. PMID:
29934701
Article Published Date
: Oct 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Diosmin
,
Flavonoids
,
Hesperidin
,
Quercetin
Diseases
:
Hemorrhoids
[+]
Flavonoid-rich dark chocolate improves endothelial function and increases plasma antioxidant concentrations in healthy adults.
Jun 01, 2004
Click here to read the entire abstract
Pubmed Data
: J Am Coll Nutr. 2004 Jun;23(3):197-204. PMID:
15190043
Article Published Date
: Jun 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Cocoa
,
Flavonoids
Diseases
:
Endothelial Dysfunction
[+]
Flavonoid-rich dark chocolate intake significantly improved coronary circulation in healthy adults.
Jan 24, 2009
Click here to read the entire abstract
Pubmed Data
: Int J Cardiol. 2009 Jan 24;131(3):424-9. Epub 2007 Nov 28. PMID:
18045712
Article Published Date
: Jan 24, 2009
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Coronary Artery Disease
[+]
Flavonoid-rich orange juice intake and altered gut microbiome in young adults with depressive symptoms.
Jun 17, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2020 Jun 18 ;12(6). Epub 2020 Jun 18. PMID:
32570775
Article Published Date
: Jun 17, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Orange
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
,
Gastrointestinal Agents
[+]
Flavonoid-rich orange juice is associated with acute improvements in cognitive function in healthy middle-aged males.
Aug 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur J Nutr. 2016 Sep ;55(6):2021-9. Epub 2015 Aug 18. PMID:
26280945
Article Published Date
: Aug 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
Flavonoids (hesperidin) have therapeutic value in the treatment of bleeding bladder varices.
Oct 01, 2003
Click here to read the entire abstract
Pubmed Data
: Actas Urol Esp. 2003 Oct;27(9):732-4. PMID:
14626685
Article Published Date
: Oct 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Hesperidin
Diseases
:
Bladder Degeneration
,
Hematuria
,
Vericose Veins: Bladder
[+]
Flavonoids and omega 3-based compoundhad beneficial effects for muscular dystrophies treatment.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Neurol. 2019 ;10:755. Epub 2019 Jul 23. PMID:
31396142
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Omega-3 Fatty Acids
Diseases
:
Muscular Dystrophies
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Flavonoids contained in fruits and vegetables, especially flavanones, might reduce the risk of non-allergic rhinitis.
Jan 29, 2020
Click here to read the entire abstract
Pubmed Data
: Public Health Nutr. 2020 Jan 30:1-9. Epub 2020 Jan 30. PMID:
31996276
Article Published Date
: Jan 29, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Allergic Rhinitis
Pharmacological Actions
:
Prophylactic Agents
Additional Keywords
:
Risk Reduction
[+]
Flavonoids from vegetables and fruits may be linked with the reduced risk of colorectal cancer.
Sep 30, 2016
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2016 Oct ;116(7):1275-1287. Epub 2016 Sep 21. PMID:
27650133
Article Published Date
: Sep 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Fruit: All
,
Vegetables: All
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Additional Keywords
:
COLORECTAL CANCER
,
Colorectal Cancer: Prevention
,
Flavonoids
,
Fruit: All
,
Risk Reduction
,
Vegetables: All
[+]
Flavonol intake and cognitive decline in middle-aged adults.
Nov 30, 2015
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2015 Dec ;18(12):1327-32. Epub 2015 Sep 1. PMID:
26325006
Article Published Date
: Nov 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Kaempferol
,
Myricetin
,
Quercetin
Diseases
:
Aging: Brain
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Flavonols and catechins have proved to be the most promising molecules for a potential protective role against prostate cancer.
Jul 31, 2018
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2018 Aug ;39:14-18. Epub 2018 May 15. PMID:
30012385
Article Published Date
: Jul 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
Hesperidin has therapeutic value in the treatment of recurrent aphthous stomatitis.
Apr 01, 2006
Click here to read the entire abstract
Pubmed Data
: Georgian Med News. 2006 Apr(133):31-3. PMID:
16705221
Article Published Date
: Apr 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Hesperidin
Diseases
:
Aphthous Ulcer
[+]
High intake of flavonoids is associated with decreased carotid atherosclerosis in middle-aged Finnish men.
Sep 30, 2007
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2007 Oct ;98(4):814-8. Epub 2007 Apr 30. PMID:
17466095
Article Published Date
: Sep 30, 2007
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Atherosclerosis
Pharmacological Actions
:
Cardioprotective
[+]
High intake of white fruits and vegetables may protect against stroke.
Oct 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Stroke. 2011 Nov ;42(11):3190-5. Epub 2011 Sep 15. PMID:
21921279
Article Published Date
: Oct 31, 2011
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Carotenoids
,
Flavonoids
,
Fruit: All
,
Vegetables: All
Diseases
:
Stroke
Additional Keywords
:
Risk Reduction
[+]
Higher anthocyanin intake is associated with lower arterial stiffness and central blood pressure in women.
Sep 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2012 Oct ;96(4):781-8. Epub 2012 Aug 22. PMID:
22914551
Article Published Date
: Sep 30, 2012
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Atherosclerosis
,
Cardiovascular Diseases
,
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
,
Vasoprotective
[+]
Higher consumption of red wine, tea, peppers, blueberries and strawberries, was associated with reduced risk of total and cause-specific mortality.
Jun 12, 2017
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2017 Jun 13:1-8. Epub 2017 Jun 13. PMID:
28606222
Article Published Date
: Jun 12, 2017
Study Type
: Human Study
Additional Links
Substances
:
Blueberry
,
Flavonoids
,
Red Wine Extract
,
Strawberry
Diseases
:
All-Cause Mortality
Additional Keywords
:
Risk Reduction
[+]
Higher dietary flavonol and isoflavonoid intakes are associated with lower incidence of type 2 diabetes.
Apr 11, 2023
Click here to read the entire abstract
Pubmed Data
: Int J Vitam Nutr Res. 2023 Apr 12. Epub 2023 Apr 12. PMID:
37042357
Article Published Date
: Apr 11, 2023
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Diabetes Mellitus: Type 2: Prevention
Additional Keywords
:
Risk Reduction
[+]
Higher dietary intake of flavonoid may be inversely associated with depressive symptoms.
Apr 23, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2018 Apr 24 ;23(5). Epub 2018 Apr 24. PMID:
29695122
Article Published Date
: Apr 23, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Depression
Additional Keywords
:
Depression
,
Flavonoids
,
Risk Reduction
[+]
Higher dietary intakes of flavonols may be associated with reduced risk of developing Alzheimer dementia.
Jan 28, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neurology. 2020 Jan 29. Epub 2020 Jan 29. PMID:
31996451
Article Published Date
: Jan 28, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
Higher flavonoid intake is associated with lower IL-1β.
Jan 29, 2020
Click here to read the entire abstract
Pubmed Data
: J Clin Periodontol. 2020 Jan 30. Epub 2020 Jan 30. PMID:
31999847
Article Published Date
: Jan 29, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Inflammation
,
Periodontal Diseases
,
Periodontal Wound Healing
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
Higher flavonoid intakes may be associated with lower depression risk.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2016 09 ;104(3):704-14. Epub 2016 Jul 13. PMID:
27413131
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
Additional Keywords
:
Risk Reduction
[+]
Higher intake of black tea and particular classes of flavonoids were associated with lower risk of fracture related hospitalizations in elderly women at high risk of fracture.
Aug 11, 2015
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2015 Aug 12. Epub 2015 Aug 12. PMID:
26269364
Article Published Date
: Aug 11, 2015
Study Type
: Human Study
Additional Links
Substances
:
Black Tea
,
Flavonoids
Diseases
:
Bone Fractures
Additional Keywords
:
Risk Reduction
[+]
Higher intake of dietary flavonols, specifically dietary quercetin, is associated with lower odds of frailty onset over 12 years of follow-up.
Apr 12, 2023
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2023 Apr 13. Epub 2023 Apr 13. PMID:
37061164
Article Published Date
: Apr 12, 2023
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Quercetin
Diseases
:
Aging
Additional Keywords
:
Risk Reduction
[+]
Higher intake of flavonoids, particularly from berries, appears to reduce rates of cognitive decline in older adults.
Jun 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Neurol. 2012 Jul ;72(1):135-43. Epub 2012 Apr 26. PMID:
22535616
Article Published Date
: Jun 30, 2012
Study Type
: Human Study
Additional Links
Substances
:
Berries: All
,
Blueberry
,
Flavonoids
,
Strawberry
Diseases
:
Aging
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
Higher intakes of anthocyanins and flavonols and their anti-inflammatory effects may be a key component underlying the reduction in risk of certain chronic diseases.
May 26, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2015 May 27. Epub 2015 May 27. PMID:
26016863
Article Published Date
: May 26, 2015
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
,
Fruit: All
,
Vegetables: All
Diseases
:
Chronic Disease
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Risk Reduction
[+]
Higher intakes of flavonols and flavanones as well as black tea consumption may be associated with lower risk of ovarian cancer.
Oct 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2014 Nov ;100(5):1344-51. Epub 2014 Aug 20. PMID:
25332332
Article Published Date
: Oct 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Black Tea
,
Flavonoids
Diseases
:
Ovarian Cancer
Additional Keywords
:
Risk Reduction
[+]
Higher intakes of fruit-based flavonoids were associated with a lower risk of nonfatal MI and ischemic stroke in men.
Aug 02, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2016 Aug 3. Epub 2016 Aug 3. PMID:
27488237
Article Published Date
: Aug 02, 2016
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
,
Fruit: All
Diseases
:
Cardiovascular Diseases
,
Myocardial Infarction
,
Stroke
Additional Keywords
:
Risk Reduction
[+]
Hyperoside alleviates postmenopausal osteoporosis.
Jun 30, 2023
Click here to read the entire abstract
Pubmed Data
: Am J Reprod Immunol. 2023 Jul ;90(1):e13709. Epub 2023 May 8. PMID:
37157916
Article Published Date
: Jun 30, 2023
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoporosis
Pharmacological Actions
:
Osteoprotective
[+]
Individuals using the Army Physical Fitness Test while supplementing with Pycnogenol had a lower increase in oxidative stress with a faster recovery to almost normal levels.
Nov 30, 2013
Click here to read the entire abstract
Pubmed Data
: J Sports Med Phys Fitness. 2013 Dec ;53(6):644-54. PMID:
24247188
Article Published Date
: Nov 30, 2013
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Athletic Performance
,
Athletic Performance: Recovery
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Supplementation
[+]
Inhibitory effect of a combination of baicalein and quercetin flavonoids against Candida albicans strains isolated from the female reproductive system.
May 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Fungal Biol. 2022 Jun-Jul;126(6-7):407-420. Epub 2022 May 8. PMID:
35667828
Article Published Date
: May 31, 2022
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Quercetin
Diseases
:
Candida Albicans
,
Candida Infection
Pharmacological Actions
:
Antifungal Agents
Additional Keywords
:
Bacterial Infections: Resistance/Biofilm Formation
[+]
Intake of flavonoid-rich wine, tea, and chocolate by elderly men and women is associated with better cognitive test performance.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2009 Jan;139(1):120-7. Epub 2008 Dec 3. PMID:
19056649
Article Published Date
: Jan 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Black Tea
,
Flavonoids
,
Green Tea
,
Wine
Diseases
:
Aging: Brain
,
Cognitive Decline/Dysfunction
[+]
Intake of flavonoids and flavonoid-rich foods, and mortality risk among individuals with Parkinson disease.
Jan 25, 2022
Click here to read the entire abstract
Pubmed Data
: Neurology. 2022 Jan 26. Epub 2022 Jan 26. PMID:
35082171
Article Published Date
: Jan 25, 2022
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavan-3-ols
,
Flavonoids
Diseases
:
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Intake of total polyphenols and some classes of polyphenols is inversely associated with diabetes in elderly People at high cardiovascular disease risk.
Mar 08, 2016
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2016 Mar 9. Epub 2016 Mar 9. PMID:
26962181
Article Published Date
: Mar 08, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cardiovascular Disease: Prevention
,
Diabetes Mellitus: Type 2: Prevention
Additional Keywords
:
Risk Reduction
[+]
L-arginine in combination with Pycnogenol causes a significant improvement in sexual function in men with erectile dysfunction without any side effects.
May 01, 2003
Click here to read the entire abstract
Pubmed Data
: J Sex Marital Ther. 2003 May-Jun;29(3):207-13. PMID:
12851125
Article Published Date
: May 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Arginine
,
Flavonoids
Diseases
:
Erectile Dysfunction
Pharmacological Actions
:
Nitric Oxide Enhancer
,
Platelet Aggregation Inhibitors
[+]
Moderate consumption of chocolate might be associated with a lower risk of heart failure in male physicians.
Nov 30, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur J Heart Fail. 2014 Dec ;16(12):1372-6. Epub 2014 Oct 14. PMID:
25311633
Article Published Date
: Nov 30, 2014
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Heart Failure
Pharmacological Actions
:
Cardioprotective
[+]
Modulation of aflatoxin biomarkers in human blood and urine by green tea polyphenols intervention.
Jan 31, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Carcinogenesis. 2008 Feb ;29(2):411-7. Epub 2008 Jan 12. PMID:
18192689
Article Published Date
: Jan 31, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Tea
Diseases
:
Aflatoxicosis
,
Liver Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
Problem Substances
:
Aflatoxin
[+]
Oligopin supplementation in traumatic brain injury patients in ICU reduced inflammation and improved the clinical status.
Aug 31, 2021
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2021 Sep ;35(9):5178-5188. Epub 2021 Aug 12. PMID:
34382717
Article Published Date
: Aug 31, 2021
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Brain Inflammation
,
Traumatic Brain Injury
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
Additional Keywords
:
Plant Extracts
[+]
One week of dark chocolate ingestion improved lipid profiles and decreased platelet reactivity within the total group while reducing inflammation only in women.
Jul 01, 1999
Click here to read the entire abstract
Pubmed Data
: Neurotoxicol Teratol. 1999 Jul-Aug;21(4):349-57. PMID:
19005437
Article Published Date
: Jul 01, 1999
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
C-Reactive Protein
,
Clotting
,
Thrombosis
[+]
Oral intake of Pycnogenol® benefits the skin in Han Chinese, who are working outdoors under considerable environmental stress.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: Skin Pharmacol Physiol. 2021 ;34(3):135-145. Epub 2021 Mar 31. PMID:
33789311
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Aging Skin
,
Dry Skin
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Orange juice intake improved depressive symptoms in young adults with major depressive disorder.
Dec 27, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2022 Dec 28 ;15(1). Epub 2022 Dec 28. PMID:
36615801
Article Published Date
: Dec 27, 2022
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Orange
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
[+]
People who preferentially consume high amounts of quercetin-containing foods have a reduced risk of thrombosis and potential CVD risk.
Aug 31, 2006
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2006 Sep ;96(3):482-8. PMID:
16925853
Article Published Date
: Aug 31, 2006
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Onion
,
Quercetin
,
Soup
Diseases
:
Cardiovascular Disease: Prevention
,
Cardiovascular Diseases
,
Thrombosis
Pharmacological Actions
:
Anti-thrombotic
,
Cardioprotective
[+]
Polyphenolic compounds from red grapes acutely improve endothelial function in patients with coronary heart disease.
Nov 30, 2005
Click here to read the entire abstract
Pubmed Data
: Eur J Cardiovasc Prev Rehabil. 2005 Dec ;12(6):596-600. PMID:
16319551
Article Published Date
: Nov 30, 2005
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Grape
,
Polyphenols
Diseases
:
Coronary Artery Disease
,
Endothelial Dysfunction
Pharmacological Actions
:
Cardioprotective
Additional Keywords
:
Phytotherapy
[+]
Prevention of edema in long flights with Pycnogenol.
Jun 30, 2005
Click here to read the entire abstract
Pubmed Data
: Clin Appl Thromb Hemost. 2005 Jul ;11(3):289-94. PMID:
16015414
Article Published Date
: Jun 30, 2005
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Leg Edema
Pharmacological Actions
:
Platelet Aggregation Inhibitors
[+]
Prevention of recurrent venous thrombosis and post-thrombotic syndrome.
May 31, 2018
Click here to read the entire abstract
Pubmed Data
: Minerva Cardioangiol. 2018 Jun ;66(3):238-245. PMID:
29795059
Article Published Date
: May 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Post-Thrombotic Syndrome
,
Venous Thrombosis
[+]
Propolis has radioprotective properties.
Aug 01, 2009
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2009 Aug;23(8):1159-68. PMID:
19165751
Article Published Date
: Aug 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Bee Propolis
,
Flavonoids
,
Polyphenols
Diseases
:
DNA damage
,
Radiation Induced Illness
Pharmacological Actions
:
Radioprotective
[+]
Pycnogenol appears to be an effective and safe supplementary management in healthy subjects with idiopathic back pain.
Nov 30, 2021
Click here to read the entire abstract
Pubmed Data
: Panminerva Med. 2021 Dec ;63(4):472-477. PMID:
34915691
Article Published Date
: Nov 30, 2021
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Back Pain
Pharmacological Actions
:
Analgesics
Additional Keywords
:
Plant Extracts
[+]
Pycnogenol has antidiabetic action in patients with type 2 diabetes.
Oct 08, 2004
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2004 Oct 8;75(21):2505-13. PMID:
15363656
Article Published Date
: Oct 08, 2004
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Hypoglycemic Agents
Additional Keywords
:
Plant Extracts
[+]
Pycnogenol has therapeutic value in the prevention of jet lag in healthy and hypertensive patients.
Oct 01, 2008
Click here to read the entire abstract
Pubmed Data
: Minerva Cardioangiol. 2008 Oct;56(5 Suppl):3-9. PMID:
19597404
Article Published Date
: Oct 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Brain Edema
,
Hypertension
,
Jet Lag
Pharmacological Actions
:
Platelet Aggregation Inhibitors
[+]
Pycnogenol improves allergic rhinitis symptoms when supplementation is started at least 5 weeks before the onset of the allergy season.
Aug 01, 2010
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2010 Aug;24(8):1115-9. PMID:
20549654
Article Published Date
: Aug 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Allergic Rhinitis
Pharmacological Actions
:
Anti-Allergic Agents
[+]
Pycnogenol improves diabetes control, lowers cardiovascular disease risk factors, and reduces the need for hypertension medication in type diabetic patients.
May 01, 2008
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2008 May;28(5):315-20. PMID:
19083426
Article Published Date
: May 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Cardiovascular Diseases
,
Diabetes: Cardiovascular Illness
,
Diabetes Mellitus: Type 2
,
Hypertension
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
Additional Keywords
:
Drug Sparing
,
Plant Extracts
[+]
Pycnogenol improves endothelial function of hypertensive patients.
Jan 02, 2004
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2004 Jan 2;74(7):855-62. PMID:
14659974
Article Published Date
: Jan 02, 2004
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Endothelial Dysfunction
,
Hypertension
Pharmacological Actions
:
Platelet Aggregation Inhibitors
Additional Keywords
:
Plant Extracts
[+]
Pycnogenol is effective in treating symptoms associated with menopausal syndrome.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Reprod Med. 2013 Jan-Feb;58(1-2):39-46. PMID:
23447917
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Climacteric
,
Menopausal Syndrome
,
Postmenopausal Disorders: Insomnia
Pharmacological Actions
:
Analgesics
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Pycnogenol may alleviate adverse effects in oncologic treatment, e.g. deep vein thrombosis.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Mol Vis. 2008;14:1288-92. Epub 2008 Jul 10. PMID:
18927527
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Chemotherapy
,
Deep Vein Thrombosis
,
Radiation Induced Illness
Pharmacological Actions
:
Antineoplastic Agents
Additional Keywords
:
Drug Side Effect Attenuation
[+]
Pycnogenol may be of value in treatment of MSU crystal-induced arthritis through its anti-inflammatory and anti-nitrosative activities.
Feb 14, 2012
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2012 Feb 15 ;52(4):765-74. Epub 2011 Dec 13. PMID:
22198264
Article Published Date
: Feb 14, 2012
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Gout
,
Hyperuricemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Pycnogenol prevents damage in the microcirculation of hypertensive patients, and allows the dose of anti-hypertensive drugs to be reduced in most patients.
Oct 01, 2006
Click here to read the entire abstract
Pubmed Data
: Clin Appl Thromb Hemost. 2006 Oct;12(4):440-4. PMID:
17000888
Article Published Date
: Oct 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Edema
,
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
,
Calcium Channel Blockers
,
Platelet Aggregation Inhibitors
Additional Keywords
:
Drug-Plant-Vitamin Synergies
,
Drug Sparing
[+]
Pycnogenol relieves symptoms of tinnitus by improving cochlear flow.
Jun 01, 2010
Click here to read the entire abstract
Pubmed Data
: Panminerva Med. 2010 Jun;52(2 Suppl 1):63-7. PMID:
20657537
Article Published Date
: Jun 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Tinnitus
[+]
Pycnogenol supplementation alleviates symptoms of Parkinson's disease with mild cognitive impairment.
Jul 31, 2022
Click here to read the entire abstract
Pubmed Data
: J Neurosurg Sci. 2022 Aug ;66(4):371-377. PMID:
36153882
Article Published Date
: Jul 31, 2022
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Pycnogenol supplementation benefits human skin by increasing skin hydration and skin elasticity.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Skin Pharmacol Physiol. 2012 ;25(2):86-92. Epub 2012 Jan 21. PMID:
22270036
Article Published Date
: Dec 31, 2011
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Aging Skin
,
Wrinkles
[+]
Quercetin and rutin may ameliorate insecticide induced oxidative stress in human erythrocytes.
Mar 01, 2010
Click here to read the entire abstract
Pubmed Data
: Toxicol In Vitro. 2010 Mar;24(2):460-4. Epub 2009 Oct 13. PMID:
19833193
Article Published Date
: Mar 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Quercetin
,
Rutin
Diseases
:
Oxidative Stress
,
Pesticide Toxicity
Pharmacological Actions
:
Antioxidants
[+]
Regular consumption of a chocolate rich in flavanols confers significant photoprotection and can thus be effective at protecting human skin from harmful UV effects.
Sep 01, 2009
Click here to read the entire abstract
Pubmed Data
: Lett Appl Microbiol. 2009 Sep;49(3):354-60. Epub 2009 Jul 14. PMID:
19735513
Article Published Date
: Sep 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Chocolate
,
Flavonoids
Diseases
:
Skin Diseases: Photo-Aging
,
Sunburn
[+]
Regular moderate intake of red wine is linked to a better women's sexual health.
Sep 30, 2009
Click here to read the entire abstract
Pubmed Data
: J Sex Med. 2009 Oct ;6(10):2772-7. Epub 2009 Jul 21. PMID:
19627470
Article Published Date
: Sep 30, 2009
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Wine
Diseases
:
Endothelial Dysfunction
,
Libido: Low
,
Sexaul Dysfunction
[+]
Restless legs syndrome: prevention with Pycnogenol and improvement of the venoarteriolar response.
May 31, 2022
Click here to read the entire abstract
Pubmed Data
: Panminerva Med. 2022 Jun ;64(2):253-258. PMID:
35815767
Article Published Date
: May 31, 2022
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Restless Legs Syndrome
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Results showed a direct association between the intake of red wine, a source of stilbenes, and the relative abundance of bacteroides.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2016 Jan ;7(1):104-9. PMID:
26437130
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Coffee
,
Flavonoids
,
Red Wine Extract
,
Stilbenes
Diseases
:
Allergic Rhinitis
,
Asthma
[+]
Rheumatoid patients subjectively benefited from the vegan diet rich in antioxidants, lactobacilli and fibre.
Nov 29, 2000
Click here to read the entire abstract
Pubmed Data
: Toxicology. 2000 Nov 30 ;155(1-3):45-53. PMID:
11156742
Article Published Date
: Nov 29, 2000
Study Type
: Human Study
Additional Links
Substances
:
Carotenoids
,
Fiber
,
Flavonoids
,
Lignans
Diseases
:
Inflammation
,
Rheumatoid Arthritis
Therapeutic Actions
:
Dietary Modification: Vegetarian
Pharmacological Actions
:
Antioxidants
[+]
Rooibos tea improves the lipid profile and redox status of adults at risk of developing cardiovascular disease.
Jan 07, 2011
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2011 Jan 7 ;133(1):46-52. Epub 2010 Sep 15. PMID:
20833235
Article Published Date
: Jan 07, 2011
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Rooibos
Diseases
:
Cardiovascular Diseases
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Sea buckthorn leaf extracts protect neuronal PC-12 cells from oxidative stress.
Jul 27, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Microbiol Biotechnol. 2017 Jul 28 ;27(7):1257-1265. PMID:
28535611
Article Published Date
: Jul 27, 2017
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Kaempferol
,
Quercetin
,
Sea buckthorn
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Short- and long-term black tea consumption reverses endothelial dysfunction in patients with coronary artery disease.
Jul 10, 2001
Click here to read the entire abstract
Pubmed Data
: Circulation. 2001 Jul 10;104(2):151-6. PMID:
11447078
Article Published Date
: Jul 10, 2001
Study Type
: Human Study
Additional Links
Substances
:
Black Tea
,
Flavonoids
,
Green Tea
,
Tea
Diseases
:
Coronary Artery Disease
,
Endothelial Dysfunction
Pharmacological Actions
:
Antioxidants
,
Vasodilator Agents
Additional Keywords
:
Plant Extracts
[+]
Short-term cocoa consumption signficantly reduces blood cholesterol.
Jul 01, 2010
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2010 Jul;92(1):218-25. Epub 2010 May 26. PMID:
20504978
Article Published Date
: Jul 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cardiovascular Diseases
,
High Cholesterol
Pharmacological Actions
:
Anticholesteremic Agents
[+]
Symptoms of Meniere's disease, flow at cochlear level and tinnitus improved in Pycnogenol subjects in comparison with best management.
May 31, 2014
Click here to read the entire abstract
Pubmed Data
: Minerva Med. 2014 Jun ;105(3):245-54. PMID:
24988090
Article Published Date
: May 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Tinnitus
Additional Keywords
:
Plant Extracts
,
Significant Treatment Outcome
[+]
Tea consumption reduces the risk of biliary tract and gallbladder diseases.
Nov 01, 2005
Click here to read the entire abstract
Pubmed Data
: Zhonghua Zhong Liu Za Zhi. 2005 Nov;27(11):667-71. PMID:
16438888
Article Published Date
: Nov 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
,
Tea: Black
Diseases
:
Bile Duct Cancer
,
Gallbladder Cancer
Pharmacological Actions
:
Chemopreventive
[+]
The consumption of some flavonoids may interact with exposure to phthalates on the risk of breast cancer.
Oct 31, 2016
Click here to read the entire abstract
Pubmed Data
: Environ Int. 2016 Nov ;96:167-172. Epub 2016 Aug 28. PMID:
27690147
Article Published Date
: Oct 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Vegetables: All
Diseases
:
Breast Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
Problem Substances
:
Phthalates
[+]
The data support the strategy of flavonoid supplementation to mitigate post-exercise oxidative stress in endurance athletes.
Nov 20, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Sport Nutr Exerc Metab. 2019 Nov 21:1-8. Epub 2019 Nov 21. PMID:
31754080
Article Published Date
: Nov 20, 2019
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Athletic Performance: Recovery
,
Oxidative Stress
Therapeutic Actions
:
Exercise: Cycling
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
MicroRNA modulator
,
Nrf2 activation
[+]
The effect of a citrus and pomegranate complex on physical fitness and mental well-being in healthy elderly.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Nutr Health Aging. 2022 ;26(9):839-846. PMID:
36156675
Article Published Date
: Dec 31, 2021
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Grapefruit
,
Lemon
,
Orange
,
Pomegranate
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
[+]
The flavonoid rich black currant ethanolic gemmotherapy extract elicits neuroprotective effects.
Apr 18, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2023 Apr 19 ;28(8). Epub 2023 Apr 19. PMID:
37110805
Article Published Date
: Apr 18, 2023
Study Type
: Human Study
Additional Links
Substances
:
Black Currant
,
Flavonoids
Diseases
:
Alcohol Toxicity
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
The flavonoids hesperidin and diosmin reduce bleeding and pain after stapled hemorrhoidopexy.
Aug 01, 2005
Click here to read the entire abstract
Pubmed Data
: Wien Klin Wochenschr. 2005 Aug;117(15-16):558-60. PMID:
16158207
Article Published Date
: Aug 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Diosmin
,
Flavonoids
,
Hesperidin
Diseases
:
Hemorrhoids
,
Postoperative Recovery
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
[+]
The high intake of flavanol-rich cocoa by the Kuna Indians may be responsible for their low blood pressure.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Cardiovasc Pharmacol. 2006;47 Suppl 2:S103-9; discussion 119-21. PMID:
16794446
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Catechin
,
Flavonoids
Diseases
:
Hypertension
Additional Keywords
:
Proanthocyanidins
[+]
The intake of flavonoids showed an inverse association with risk of cardiovascular events.
Oct 03, 2018
Click here to read the entire abstract
Pubmed Data
: Nutr Metab Cardiovasc Dis. 2018 Oct 4. Epub 2018 Oct 4. PMID:
30459074
Article Published Date
: Oct 03, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cardiovascular Diseases
Additional Keywords
:
Risk Reduction
[+]
The intake of flavonoids, particularly from solid fruit, is associated with better pulmonary function in patients with COPD.
Jul 01, 2001
Click here to read the entire abstract
Pubmed Data
: Am J Respir Crit Care Med. 2001 Jul 1;164(1):61-4. PMID:
11435239
Article Published Date
: Jul 01, 2001
Study Type
: Human Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Fruit: All
Diseases
:
Chronic Obstructive Pulmonary Disease
[+]
The Mediterranean diet, which includes a combination of antioxidant compounds and flavonoid-rich foods, appears effective to decrease LDL particle oxidizability, which reduces the risk for cardiovascular disease.
Oct 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2006 Oct;17(10):645-58. Epub 2006 Feb 3. PMID:
16517144
Article Published Date
: Oct 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Arteriosclerosis
,
Cardiovascular Diseases
,
Cholesterol: Oxidation
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Antioxidants
[+]
The oral intake of Pycnogenol down-regulated the gene expression of various cartilage degradation markers in the patients' chondrocytes.
Dec 15, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2017 Dec 16 ;17(1):537. Epub 2017 Dec 16. PMID:
29246219
Article Published Date
: Dec 15, 2017
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoarthritis: Knee
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
[+]
The present results suggest that high intakes of flavonoids may be associated with decreased risk of ischaemic stroke and possibly with reduced CVD mortality.
Sep 30, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2008 Oct ;100(4):890-5. Epub 2008 Apr 1. PMID:
18377681
Article Published Date
: Sep 30, 2008
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Cardiac Mortality
,
Cardiovascular Diseases
,
Stroke
Pharmacological Actions
:
Cardioprotective
,
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
The regular consumption of cocoa products containing flavanols may reduce risk of cardiovascular disease.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Asia Pac J Clin Nutr. 2008;17 Suppl 1:284-7. PMID:
18296357
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Cardiovascular Diseases
,
Endothelial Dysfunction
,
Hypertension
Additional Keywords
:
Risk Reduction
[+]
The results of the present study add to the current literature further evidence of the association between higher flavonoid intake and decreased body weight.
Mar 25, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Food Sci Nutr. 2018 Mar 26:1-10. Epub 2018 Mar 26. PMID:
29575952
Article Published Date
: Mar 25, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Obesity
Additional Keywords
:
Anti-Obesity Agents
,
Flavonoids
,
obesity
[+]
The results suggest that dietary isorhamnetin could have a potential role in coronary artery disease prevention.
Sep 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Environ Res Public Health. 2022 Oct 1 ;19(19). Epub 2022 Oct 1. PMID:
36231844
Article Published Date
: Sep 30, 2022
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Coronary Artery Disease
Pharmacological Actions
:
Cardioprotective
Additional Keywords
:
Risk Reduction
[+]
The risk of lung cancer related to dietary intake of flavonoids.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Cancer. 2012 ;64(7):964-74. PMID:
23061904
Article Published Date
: Dec 31, 2011
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Lung Cancer
,
Squamous cell carcinoma
Pharmacological Actions
:
Chemopreventive
[+]
These findings suggest a protective association between dietary intake of flavonoids and the likelihood of having age-related macular degeneration.
Jul 05, 2018
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2018 Jul 6. Epub 2018 Jul 6. PMID:
29982448
Article Published Date
: Jul 05, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Orange
Diseases
:
Macular Degeneration
Additional Keywords
:
Risk Reduction
[+]
These findings suggest that the intake of some flavonoids may reduce Parkinson’s disease risk.
Apr 09, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neurology. 2012 Apr 10 ;78(15):1138-45. Epub 2012 Apr 4. PMID:
22491871
Article Published Date
: Apr 09, 2012
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Parkinson's Disease
Additional Keywords
:
Risk Reduction
[+]
These findings support a benefit of higher flavonoid intakes for maintaining cognitive function.
Jan 06, 2021
Click here to read the entire abstract
Pubmed Data
: Neurology. 2021 09 7 ;97(10):e1041-e1056. Epub 2021 Jul 28. PMID:
34321362
Article Published Date
: Jan 06, 2021
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
These results indicate that flavonoid intake is associated with lower head and neck cancer risk.
Jul 18, 2017
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2017 Jul 19. Epub 2017 Jul 19. PMID:
28724656
Article Published Date
: Jul 18, 2017
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Head and Neck Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
This data indicate an inverse association between isoflavones and flavones with respect to bladder cancer risk.
Apr 30, 2019
Click here to read the entire abstract
Pubmed Data
: Cancer Causes Control. 2019 May ;30(5):527-535. Epub 2019 Mar 22. PMID:
30903485
Article Published Date
: Apr 30, 2019
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
,
Isoflavones
Diseases
:
Bladder Cancer
Pharmacological Actions
:
Chemopreventive
[+]
This pilot study provides the first evidence of miRNA modulation by diet and other factors, that can be detected consistently in both plasma and stools samples.
Aug 31, 2014
Click here to read the entire abstract
Pubmed Data
: Mutagenesis. 2014 Sep ;29(5):385-91. PMID:
25150024
Article Published Date
: Aug 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Pharmacological Actions
:
MicroRNA modulator
Additional Keywords
:
Dietary Concentrations
,
Epigenetic Modification
[+]
This study compares the anti-aging potential of ginkgo biloba and topical tea preparations.
Apr 01, 2010
Click here to read the entire abstract
Pubmed Data
: Int J Cosmet Sci. 2010 Apr ;32(2):99-106. PMID:
20412217
Article Published Date
: Apr 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Ginkgo biloba
,
Green Tea
,
Rooibos
Diseases
:
Aging Skin
Additional Keywords
:
Plant Extracts
[+]
This study demonstrates the efficacy of flavonoid rich berries in maintaining or improving cognitive performance.
Nov 05, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Nov 6 ;11(11). Epub 2019 Nov 6. PMID:
31698695
Article Published Date
: Nov 05, 2019
Study Type
: Human Study
Additional Links
Substances
:
Berries: All
,
Blackberry
,
Blueberry
,
Flavonoids
,
Raspberry
,
Strawberry
Diseases
:
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
This study indicates that total flavonoids and most flavonoid subclasses intakes were inversely associated with breast cancer risk.
Nov 13, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Cancer Prev. 2019 Nov 14. Epub 2019 Nov 14. PMID:
31738218
Article Published Date
: Nov 13, 2019
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Breast Cancer
Pharmacological Actions
:
Chemopreventive
[+]
This study provides evidence for a preventive effect of flavonols on pancreatic cancer.
Oct 14, 2007
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Epidemiol. 2007 Oct 15 ;166(8):924-31. Epub 2007 Aug 9. PMID:
17690219
Article Published Date
: Oct 14, 2007
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
This study provides further support for a beneficial effect of flavonoid intake on lung cancer risk
Jul 31, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Cancer. 2008 Aug 1 ;123(3):664-71. PMID:
18491403
Article Published Date
: Jul 31, 2008
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
,
Isoflavones
Diseases
:
Lung Cancer
,
Smoking
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Proanthocyanidins
[+]
This study provides support for a beneficial effect of selected flavonoids on laryngeal cancer risk.
May 31, 2007
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Oncol. 2007 Jun ;18(6):1104-9. Epub 2007 Mar 19. PMID:
17372161
Article Published Date
: May 31, 2007
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Laryngeal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Topical diosmin has therapeutic effects in the treatment of acute hemorrhoid pathology.
May 01, 1988
Click here to read the entire abstract
Pubmed Data
: Minerva Med. 1988 May;79(5):387-90. PMID:
3287228
Article Published Date
: May 01, 1988
Study Type
: Human Study
Additional Links
Substances
:
Diosmin
,
Flavonoids
Diseases
:
Hemorrhoids
[+]
Wine consumption reduces TNF-apha-induced adhesion of monocytes to endothelial cells.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Cell Physiol Biochem. 2010;26(3):471-82. Epub 2010 Aug 24. PMID:
15213052
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Wine
Diseases
:
Arteriosclerosis
,
Heart Disease: Ischemic
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Apigenin highly upregulated the expression of cytokine genes and induced apoptosis in human pancreatic cancer cells.
Nov 30, 2013
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2013 Dec ;57(12):2112-27. Epub 2013 Aug 14. PMID:
23943362
Article Published Date
: Nov 30, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
,
Flavonoids
Diseases
:
Inflammation
,
Pancreatic Cancer
Pharmacological Actions
:
Anti Inflammatory
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Epigenetic Modification In Cancer
[+]
Baicalin enhances the proliferation and invasion of trophoblasts and suppresses vascular endothelial damage in hypertensive disorder complicating pregnancy.
Aug 31, 2021
Click here to read the entire abstract
Pubmed Data
: J Obstet Gynaecol Res. 2021 Sep ;47(9):3060-3070. Epub 2021 Jun 7. PMID:
34101306
Article Published Date
: Aug 31, 2021
Study Type
: Human In Vitro
Additional Links
Substances
:
Flavonoids
Diseases
:
Hypertension
,
Pregnancy Complications
Pharmacological Actions
:
MicroRNA modulator
[+]
chokeberry juice inhibited Caco-2 cell proliferation by causing G(2)/M cell cycle arrest.
Mar 31, 2007
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2007 Apr ;18(4):259-71. Epub 2006 Jul 24. PMID:
16860979
Article Published Date
: Mar 31, 2007
Study Type
: Human In Vitro
Additional Links
Substances
:
Chokeberry
,
Flavonoids
,
Polyphenols
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Antiproliferative
,
Cell cycle arrest
,
Chemopreventive
[+]
Flavonoid mixture inhibits Mycobacterium tuberculosis survival and infectivity.
Feb 27, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2019 Feb 28 ;24(5). Epub 2019 Feb 28. PMID:
30823377
Article Published Date
: Feb 27, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Flavonoids
Diseases
:
Mycobacterium Tuberculosis
Pharmacological Actions
:
Glutathione Upregulation
,
Immunomodulatory
[+]
Luteolin prevents angiotensin II-induced cardiac remodeling.
Jan 01, 2015
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2015 ;10(9):e0137106. Epub 2015 Sep 1. PMID:
26327560
Article Published Date
: Jan 01, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Flavonoids
,
Luteolin
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
O. majorana and F. vulgare aqueous extracts showed dose and time dependent anti-Blastocystis activity.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2018 Apr 1 ;43:158-163. Epub 2018 Apr 10. PMID:
29747749
Article Published Date
: Mar 31, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Fennel
,
Flavonoids
,
Oregano
Diseases
:
Blastocystis hominis infections
Pharmacological Actions
:
Antioxidants
,
Antiparasitic Agents
Additional Keywords
:
Natural Substances Versus Drugs
,
Plant Extracts
[+]
Acacetin alleviates energy metabolism disorder through promoting white fat browning mediated by AC-cAMP pathway.
Feb 12, 2023
Click here to read the entire abstract
Pubmed Data
: J Physiol Biochem. 2023 Feb 13. Epub 2023 Feb 13. PMID:
36781604
Article Published Date
: Feb 12, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Acacetin and pinostrobin as a promising inhibitor of cancer-associated protein kinases.
Apr 30, 2021
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2021 May ;151:112091. Epub 2021 Feb 26. PMID:
33647348
Article Published Date
: Apr 30, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Cancers: All
Pharmacological Actions
:
Chemopreventive
[+]
Acacetin attenuates diabetes-induced cardiomyopathy.
May 04, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur J Pharmacol. 2022 May 5 ;922:174916. Epub 2022 Mar 24. PMID:
35341782
Article Published Date
: May 04, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Diabetes: Cardiovascular Illness
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Interleukin-6 Downregulation
[+]
Acacetin can protect DA neurons against the neurotoxicity involved in Parkinson's disease via its anti-inflammatory action.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2012 ;35(8):1287-94. PMID:
22863927
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Inflammation
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Acacetin exerts antitumor effects on gastric cancer by targeting EGFR.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2023 ;14:1121643. Epub 2023 May 17. PMID:
37266143
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Apoptotic
[+]
Acacetin inhibits in vitro and in vivo angiogenesis and downregulates Stat signaling and VEGF expression.
Sep 30, 2013
Click here to read the entire abstract
Pubmed Data
: Cancer Prev Res (Phila). 2013 Oct ;6(10):1128-39. Epub 2013 Aug 13. PMID:
23943785
Article Published Date
: Sep 30, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Cancer Metastasis
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Antineoplastic Agents
,
Antiproliferative
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Acacetin inhibits invasion, migration and TGF-β1-induced EMT of gastric cancer cells.
Jan 08, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Med Ther. 2022 Jan 9 ;22(1):10. Epub 2022 Jan 9. PMID:
35000605
Article Published Date
: Jan 08, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Anti-metastatic
,
Transforming growth factor beta (TGF-β) inhibitor
[+]
Acacetin prevents bone loss by disrupting osteoclast formation and promoting type H vessel formation in ovariectomy-induced osteoporosis.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Cell Dev Biol. 2022 ;10:796227. Epub 2022 Apr 19. PMID:
35517504
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoporosis
Pharmacological Actions
:
Osteoprotective
[+]
Agathisflavone modulates astrocytic responses and increases the population of neurons in an in vitro model of traumatic brain injury.
Jan 09, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Naunyn Schmiedebergs Arch Pharmacol. 2020 10 ;393(10):1921-1930. Epub 2020 May 22. PMID:
32444988
Article Published Date
: Jan 09, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Traumatic Brain Injury
Pharmacological Actions
:
Neuroprotective Agents
[+]
Amentoflavone induces caspase-dependent/-independent apoptosis and dysregulates cyclin-dependent kinase-mediated cell cycle in colorectal cancer.
Apr 30, 2023
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2023 May ;38(5):1078-1089. Epub 2023 Feb 2. PMID:
36727907
Article Published Date
: Apr 30, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Apoptotic
,
Cell cycle arrest
,
Tumor Suppressor Protein p53 Upregulation
[+]
Anti-hyperuricemic effect of taxifolin in cultured hepatocytes and model mice.
Mar 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cytotechnology. 2017 Apr ;69(2):329-336. Epub 2017 Jan 18. PMID:
28101741
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Hyperuricemia
Pharmacological Actions
:
Uricosuric Agents
[+]
Baicalin acts as an adjuvant to potentiate the activity of azithromycin against Staphylococcus saprophyticus biofilm: an in vitro, in vivo, and molecular study.
Oct 11, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Vet Res. 2022 Oct 12 ;53(1):83. Epub 2022 Oct 12. PMID:
36224607
Article Published Date
: Oct 11, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Staphylococcal Infections
Pharmacological Actions
:
Anti-Bacterial Agents
Additional Keywords
:
Bacterial Infections: Resistance/Biofilm Formation
,
Natural Substance/Drug Synergy
[+]
Baicalin ameliorates alcohol-induced hepatic steatosis.
Jan 14, 2022
Click here to read the entire abstract
Pubmed Data
: Arch Biochem Biophys. 2022 06 15 ;722:109236. Epub 2022 Apr 13. PMID:
35429444
Article Published Date
: Jan 14, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Alcohol Toxicity
,
Liver Steatosis
Pharmacological Actions
:
Hepatoprotective
[+]
Baicalin ameliorates radiation-induced lung injury.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2022 ;2022:2765354. Epub 2022 Jun 24. PMID:
35783527
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lung Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Transforming growth factor beta (TGF-β) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Baicalin exhibited a potential therapeutic effect on prostate cancer.
Sep 30, 2023
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2023 Oct ;29(10):914-923. Epub 2023 Jun 26. PMID:
37357241
Article Published Date
: Sep 30, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Apoptotic
,
NF-kappaB Inhibitor
Additional Keywords
:
Cancer Stem Cells
[+]
Baicalin improved hepatic injury of NASH by regulating NRF2/HO-1/NRLP3 pathway.
Nov 04, 2022
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2022 Nov 5 ;934:175270. Epub 2022 Sep 20. PMID:
36184988
Article Published Date
: Nov 04, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Skullcap: Chinese
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Hepatoprotective
,
Nrf2 activation
[+]
Baicalin induces a potent innate immune response to inhibit respiratory syncytial virus replication.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Immunol. 2022 ;13:907047. Epub 2022 Jun 23. PMID:
35812414
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Respiratory Syncytial Virus Infections
Pharmacological Actions
:
Antiviral Agents
[+]
Baicalin relieves LPS-induced lung inflammation.
Feb 15, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2023 Feb 16 ;28(4). Epub 2023 Feb 16. PMID:
36838858
Article Published Date
: Feb 15, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cardiac senescence is alleviated by the natural flavone acacetin via enhancing mitophagy.
Jun 26, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Aging (Albany NY). 2021 Jun 27 ;13(12):16381-16403. Epub 2021 Jun 27. PMID:
34175838
Article Published Date
: Jun 26, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Aging
,
Cardiomyopathy
Pharmacological Actions
:
Cardioprotective
[+]
Farrerol alleviates myocardial ischemia/reperfusion injury.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:879232. Epub 2022 Apr 13. PMID:
35496295
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Farrerol ameliorates TNBS-induced colonic inflammation.
Jul 12, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2018 Jul 13 ;19(7). Epub 2018 Jul 13. PMID:
30011811
Article Published Date
: Jul 12, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Colitis
,
Gastrointestinal Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
[+]
Farrerol attenuates cisplatin-induced nephrotoxicity.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Physiol. 2019 ;10:1419. Epub 2019 Nov 26. PMID:
31849693
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Renoprotective
[+]
Galangin ameliorates osteoarthritis progression by attenuating extracellular matrix degradation in chondrocytes.
Dec 04, 2022
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2022 Dec 5 ;936:175347. Epub 2022 Oct 29. PMID:
36367487
Article Published Date
: Dec 04, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Antioxidants
,
Osteoprotective
[+]
Galangin enhances anticancer efficacy of 5-fluorouracil in esophageal cancer cells.
Dec 16, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Med Sci Monit. 2021 Dec 17 ;27:e931630. Epub 2021 Dec 17. PMID:
34916479
Article Published Date
: Dec 16, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Esophageal Cancer
Pharmacological Actions
:
Apoptotic
Additional Keywords
:
Chemothapeutic Synergy: 5-flourouracil
[+]
Galangin inhibits programmed cell death-ligand 1 expression by suppressing STAT3 and MYC and enhances T cell tumor-killing activity.
Jul 24, 2023
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2023 Jul 25 ;116:154877. Epub 2023 May 20. PMID:
37267692
Article Published Date
: Jul 24, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Glabridin inhibits urothelial bladder carcinoma cell growth.
Sep 12, 2022
Click here to read the entire abstract
Pubmed Data
: Chem Biol Drug Des. 2022 Sep 13. Epub 2022 Sep 13. PMID:
36098706
Article Published Date
: Sep 12, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Licorice
Diseases
:
Bladder Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
[+]
Hesperetin ameliorates spinal cord injury by inhibiting NLRP3 inflammasome.
Apr 30, 2023
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2023 May ;118:110103. Epub 2023 Mar 29. PMID:
37001385
Article Published Date
: Apr 30, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
,
Nrf2 activation
[+]
Hyperoside ameliorates renal tubular oxidative damage and calcium oxalate deposition.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Renin Angiotensin Aldosterone Syst. 2023 ;2023:5445548. Epub 2023 Mar 11. PMID:
36942317
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Nephrolithiasis
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Nrf2 activation
[+]
Hyperoside attenuates Cd-induced kidney injury via inhibiting NLRP3 inflammasome activation and ROS/MAPK/NF-κB signaling pathway.
Jan 31, 2023
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2023 Feb ;172:113601. Epub 2023 Jan 5. PMID:
36610472
Article Published Date
: Jan 31, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Icariin ameliorates endothelial dysfunction in type 1 diabetes.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: J Cell Physiol. 2021 03 ;236(3):1889-1902. Epub 2020 Aug 7. PMID:
32770555
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Icariin
Diseases
:
Diabetes Mellitus: Type 1
,
Endothelial Dysfunction
Pharmacological Actions
:
Antioxidants
[+]
Isoginkgetin protects against obesity-induced cardiomyopathy via enhancing Nrf2/ARE signaling.
Sep 19, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Redox Biol. 2022 Sep 20 ;57:102485. Epub 2022 Sep 20. PMID:
36162256
Article Published Date
: Sep 19, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Ginkgo biloba
Diseases
:
Cardiomyopathy
,
Obesity
Pharmacological Actions
:
Cardioprotective
[+]
Isorhamnetin alleviates lipopolysaccharide-induced acute lung injury.
May 31, 2022
Click here to read the entire abstract
Pubmed Data
: Immunopharmacol Immunotoxicol. 2022 Jun ;44(3):387-399. Epub 2022 Mar 21. PMID:
35306954
Article Published Date
: May 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Apoptotic
,
Autophagy Up-regulation
,
NF-kappaB Inhibitor
[+]
Isorhamnetin induces apoptosis and suppresses metastasis of human endometrial carcinoma Ishikawa cell.
Oct 27, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Foods. 2022 Oct 28 ;11(21). Epub 2022 Oct 28. PMID:
36360027
Article Published Date
: Oct 27, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Endometrial Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
[+]
Isorhamnetin induces cell cycle arrest and apoptosis in doxorubicin-resistant breast cancer.
May 31, 2023
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2023 Jun ;114:154780. Epub 2023 Mar 21. PMID:
37004402
Article Published Date
: May 31, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Breast Cancer
,
Cancers: Drug Resistant
,
DNA damage
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemosensitizer
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
[+]
Liquiritin attenuates pathological cardiac hypertrophy.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:870699. Epub 2022 May 3. PMID:
35592411
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Licorice
Diseases
:
Cardiac Hypertrophy
Pharmacological Actions
:
Cardioprotective
[+]
Liquiritin exhibits anti-acute lung injury activities.
Apr 02, 2023
Click here to read the entire abstract
Pubmed Data
: Chin Med. 2023 Apr 3 ;18(1):35. Epub 2023 Apr 3. PMID:
37013552
Article Published Date
: Apr 02, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Licorice
Diseases
:
Lung Damage
[+]
Liquiritin reduces ferroptosis in doxorubicin-induced cardiotoxicity.
May 08, 2023
Click here to read the entire abstract
Pubmed Data
: Naunyn Schmiedebergs Arch Pharmacol. 2023 May 9. Epub 2023 May 9. PMID:
37160483
Article Published Date
: May 08, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Licorice
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Molecular mechanism of ion channel protein TMEM16A regulated by natural product of narirutin for lung cancer adjuvant treatment.
Dec 30, 2022
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2022 Dec 31 ;223(Pt A):1145-1157. Epub 2022 Nov 15. PMID:
36400205
Article Published Date
: Dec 30, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Carcinoma: Non-Small-Cell Lung
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemosensitizer
Additional Keywords
:
Chemotherapeutic Synergy: Cisplatin
[+]
Narirutin affects the Th1/Th2 imbalance through the p-ERK and p-JNK suppression.
Nov 30, 2022
Click here to read the entire abstract
Pubmed Data
: Iran J Immunol. 2022 Dec ;19(4):385-394. PMID:
36585880
Article Published Date
: Nov 30, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Asthma
Pharmacological Actions
:
Immunomodulatory
[+]
Narirutin exerts anti-inflammatory activity by inhibiting NLRP3 inflammasome activation.
Mar 31, 2023
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2023 Apr ;37(4):1293-1308. Epub 2023 Feb 7. PMID:
36751854
Article Published Date
: Mar 31, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Colitis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
Oroxylin A exerts its antitumor effects in human gallbladder cancer.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2020 ;43(10):1511-1518. PMID:
32999161
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Gallbladder Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Apoptotic
[+]
Pinocembrin ameliorates acute liver failure via activating the Sirt1/PPARα pathway in vitro and in vivo.
Jan 14, 2022
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2022 Jan 15 ;915:174610. Epub 2021 Dec 21. PMID:
34951978
Article Published Date
: Jan 14, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Liver Failure: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Protective effects of liquiritigenin against cisplatin-induced nephrotoxicity.
Jun 13, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2022 Jun 14 ;27(12). Epub 2022 Jun 14. PMID:
35744945
Article Published Date
: Jun 13, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Licorice
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
Sinensetin ameliorates high glucose-induced diabetic nephropathy.
Jul 01, 2023
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2023 Jul 2:e23445. Epub 2023 Jul 2. PMID:
37393522
Article Published Date
: Jul 01, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Renoprotective
[+]
Sinensetin reduces osteoarthritis pathology in the tert-butyl hydroperoxide-treated chondrocytes.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2021 ;12:713491. Epub 2021 Jul 16. PMID:
34335275
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Apoptotic
,
Osteoprotective
[+]
Taxifolin is a potent antihyperglycemic and antihyperuricemic phytochemical in the T2D state.
Sep 25, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Curr Issues Mol Biol. 2021 Sep 26 ;43(3):1293-1306. Epub 2021 Sep 26. PMID:
34698101
Article Published Date
: Sep 25, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Diabetes Mellitus: Type 2
,
Hyperuricemia
Pharmacological Actions
:
Hypoglycemic Agents
[+]
Taxifolin prevents diabetic cardiomyopathy in vivo and in vitro by inhibition of oxidative stress and cell apoptosis.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2014 Jan ;63:221-32. Epub 2013 Nov 20. PMID:
24269735
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Cardiomyopathy
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
The anti-tumor effect of taxifolin on lung cancer via suppressing stemness and epithelial-mesenchymal transition.
Apr 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Transl Med. 2020 May ;8(9):590. PMID:
32566617
Article Published Date
: Apr 30, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
Additional Keywords
:
Cancer Stem Cells
[+]
This study provides theoretical support for the research and development of hyperoside in fat-reducing functional foods.
May 21, 2023
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2023 May 22 ;14(10):4763-4776. Epub 2023 May 22. PMID:
37128768
Article Published Date
: May 21, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Obesity
Pharmacological Actions
:
Hypolipidemic
Additional Keywords
:
Anti-Obesity Agents
[+]
Tilianin protects against ischemia/reperfusion-induced myocardial injury.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2020 ;2020:5939715. Epub 2020 Oct 9. PMID:
33102583
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Inflammation
,
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Cardioprotective
,
NF-kappaB Inhibitor
[+]
Tiliroside induces ferroptosis to repress the development of triple-negative breast cancer cells.
Jul 31, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Tissue Cell. 2023 Aug ;83:102116. Epub 2023 May 16. PMID:
37301139
Article Published Date
: Jul 31, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Chemopreventive
[+]
Baicalin protects LPS-induced blood-brain barrier damage and activates Nrf2-mediated antioxidant stress pathway
Jun 30, 2021
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2021 Jul ;96:107725. Epub 2021 May 28. PMID:
34162131
Article Published Date
: Jun 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Neurodegenerative Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin and hesperetin attenuate D-galactose-induced brain senescence in vitro and in vivo
Sep 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Res Pract. 2020 Oct ;14(5):438-452. Epub 2020 Aug 6. PMID:
33029285
Article Published Date
: Sep 30, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
Diseases
:
Neurodegenerative Diseases
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Enhancement of epithelial cell autophagy induced by sinensetin alleviates epithelial barrier dysfunction in colitis.
Jan 09, 2019
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2019 10 ;148:104461. Epub 2019 Sep 19. PMID:
31542404
Article Published Date
: Jan 09, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Colitis
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Optimization of extraction flavonoids from Exocarpium Citri Grandis and evaluation its hypoglycemic and hypolipidemic activities.
Nov 14, 2020
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2020 Nov 15 ;262:113178. Epub 2020 Jul 28. PMID:
32736047
Article Published Date
: Nov 14, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Hyperglycemia
,
Hyperlipidemia
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
[+]
Poncirin prevents bone loss in glucocorticoid-induced osteoporosis in vivo and in vitro.
Aug 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Bone Miner Metab. 2012 Sep ;30(5):509-16. Epub 2012 Mar 13. PMID:
22407507
Article Published Date
: Aug 31, 2012
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoporosis
Pharmacological Actions
:
Osteoprotective
[+]
"Chrysin abrogates early hepatocarcinogenesis and induces apoptosis in N-nitrosodiethylamine-induced preneoplastic nodules in rats."
Feb 15, 2011
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2011 Feb 15 ;251(1):85-94. Epub 2010 Dec 15. PMID:
21167192
Article Published Date
: Feb 15, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Liver Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Tumor Suppressor Protein p53 Upregulation
[+]
A cocoa diet enhances thymus antioxidant defenses and influences thymocyte differentiation.
Aug 08, 2007
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2007 Aug 8;55(16):6431-8. Epub 2007 Jul 14. PMID:
17630760
Article Published Date
: Aug 08, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Polyphenols
Diseases
:
Low Immune Function: Thymus Dysfunction
Pharmacological Actions
:
Antioxidants
,
Immunomodulatory
[+]
A cocoa-enriched diet prevents gingival oxidative stress in experimental periodontitis.
Nov 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Periodontol. 2009 Nov;80(11):1799-808. PMID:
19905949
Article Published Date
: Nov 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Cocoa
,
Flavonoids
,
Polyphenols
Diseases
:
Periodontitis
Pharmacological Actions
:
Antioxidants
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A combination of baicalin and berberine hydrochloride ameliorates dextran sulfate sodium-induced colitis.
Jul 31, 2022
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2022 Aug ;25(8):853-862. PMID:
35980327
Article Published Date
: Jul 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
,
Flavonoids
Diseases
:
Colitis
,
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer.
Mar 26, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2019 Mar 27. Epub 2019 Mar 27. PMID:
30919084
Article Published Date
: Mar 26, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bergamot
,
Flavonoids
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-10 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
A mixture of phytochemicals naturally present in foods represents a plausible chemopreventive agent for colorectal cancer.
May 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2011 Jun ;4(6):907-15. Epub 2011 Mar 7. PMID:
21383028
Article Published Date
: May 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Apple Polyphenols
,
Apples
,
Flavonoids
Diseases
:
Colon Polyps
,
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Antioxidants
,
Chemopreventive
Additional Keywords
:
Dietary Concentrations
[+]
A natural flavonoid present in unripe plantain banana pulp (Musa sapientum L. var. paradisiaca) protects the gastric mucosa from aspirin-induced erosions.
Jun 01, 1999
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 1999 Jun;65(3):283-8. PMID:
10404428
Article Published Date
: Jun 01, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Banana
,
Flavonoids
Diseases
:
Aspirin-Induced Toxicity
,
NSAID-induced toxicity
Pharmacological Actions
:
Anti-Ulcer Agents
[+]
A polyphenol extract from red grapes redues fat content in an animal model of non-alcoholic liver disease.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2010 Dec;104(12):1760-70. Epub 2010 Aug 2. PMID:
20673376
Article Published Date
: Dec 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Grape
,
Polyphenols
,
Resveratrol
Diseases
:
Fatty Liver
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
A. esculentus flowers protects against transient cerebral ischemia-reperfusion injury.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:8987173. Epub 2018 Aug 5. PMID:
30174782
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Okra
Diseases
:
Brain Ischemia
,
Cerebral Ischemia
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 inducer
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Nitric Oxide Inhibitor
,
Nrf2 activation
[+]
Acacetin alleviates hepatitis following renal ischemia-reperfusion.
Apr 30, 2021
Click here to read the entire abstract
Pubmed Data
: J Invest Surg. 2021 May ;34(5):495-503. Epub 2019 Nov 5. PMID:
31686554
Article Published Date
: Apr 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Hepatitis
,
Ischemia
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Renoprotective
[+]
Acacetin alleviates inflammation and matrix degradation in nucleus pulposus cells and ameliorates intervertebral disc degeneration.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2020 ;14:4801-4813. Epub 2020 Nov 10. PMID:
33204066
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Degenerative Disk Disease
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Acacetin alleviates myocardial ischaemia/reperfusion injury.
Nov 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2022 Dec ;60(1):553-561. PMID:
35244510
Article Published Date
: Nov 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Myocardial Ischemia
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Bcl-2 protein down-regulation
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
[+]
Acacetin alleviates neuroinflammation and oxidative stress injury.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Transl Neurosci. 2022 Jan 1 ;13(1):483-494. Epub 2022 Dec 21. PMID:
36590896
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Brain Inflammation
,
Spinal Cord Injuries
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Acacetin ameliorates cardiac hypertrophy by activating Sirt1/AMPK/PGC-1α pathway.
Apr 04, 2022
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2022 Apr 5 ;920:174858. Epub 2022 Feb 24. PMID:
35219729
Article Published Date
: Apr 04, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Cardiac Hypertrophy
,
Cardiomegaly
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Nrf2 activation
[+]
Acacetin ameliorates experimental colitis.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Physiol. 2020 ;11:577237. Epub 2021 Jan 18. PMID:
33536931
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
[+]
Acacetin ameliorates insulin resistance in obesity.
Mar 28, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Endocr Disord. 2021 Mar 29 ;21(1):57. Epub 2021 Mar 29. PMID:
33781239
Article Published Date
: Mar 28, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Insulin Sensitizers
,
MicroRNA modulator
[+]
Acacetin attenuates mice endotoxin-induced acute lung injury via augmentation of heme oxygenase-1 activity.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2018 Apr ;26(2):635-643. Epub 2017 Oct 7. PMID:
28988328
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Endotoxemia
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Acacetin attenuates neuroinflammation.
Jun 30, 2012
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2012 Jul ;37(7):1560-7. Epub 2012 Mar 24. PMID:
22447574
Article Published Date
: Jun 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Neuroprotective Agents
,
Postaglandin PGE2 downregulation
[+]
Acacetin attenuates renal damage-induced by ischemia-reperfusion.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Prev Med. 2020 ;11:22. Epub 2020 Feb 17. PMID:
32175062
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Renoprotective
[+]
Acacetin attenuates the pancreatic and hepatorenal dysfunction in type 2 diabetes.
May 31, 2023
Click here to read the entire abstract
Pubmed Data
: J Nat Med. 2023 Jun ;77(3):446-454. Epub 2023 Mar 9. PMID:
36892720
Article Published Date
: May 31, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Pancreato Protective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Acacetin effectively mitigated photoaging by targeting the promotion of SIRT3.
Jul 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cell Mol Med. 2022 Aug ;26(16):4624-4628. Epub 2022 Jun 28. PMID:
35765710
Article Published Date
: Jul 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Aging Skin
,
Ultraviolet Radiation Induced Damage
Therapeutic Actions
:
Sunlight exposure
Pharmacological Actions
:
Photoprotective
[+]
Acacetin exerts antioxidant potential against atherosclerosis.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cell Mol Med. 2021 Jan ;25(1):521-534. Epub 2020 Nov 26. PMID:
33241629
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Atherosclerosis
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Nrf2 activation
[+]
Acacetin improves cognitive function of APP/PS1 Alzheimer's disease model.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Transl Neurosci. 2022 Jan 1 ;13(1):390-397. Epub 2022 Oct 31. PMID:
36382256
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Acacetin improves endothelial dysfunction and aortic fibrosis in insulin-resistant SHR rats.
Aug 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Biol Rep. 2020 Sep ;47(9):6899-6918. Epub 2020 Sep 6. PMID:
32892299
Article Published Date
: Aug 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Endothelial Dysfunction
,