Frankincense

Name	AC	CK
Osteoarthritis: Knee	14	122
Inflammation	27	71
Osteoarthritis	15	67
Breast Cancer	12	35
Alzheimer's Disease	10	25
Memory Disorders	5	25
Wound Healing	4	25
Irritable Bowel Syndrome	3	21
Brain Edema	2	20
Multiple Sclerosis: Relapsing-Remitting	2	20
Oxidative Stress	8	20
Pain	2	20
Traumatic Brain Injury	2	20
Arthritis	6	18
Cancers: All	7	16
Cognitive Decline/Dysfunction	4	16
Diabetes Mellitus: Type 2	4	14
Ulcerative Colitis	4	14
Asthma	4	13
Coronavirus Infection	4	13
Lipid Peroxidation	3	13
Brain Inflammation	3	12
Brain Ischemia	2	11
Chronic Pain	2	11
Depression	2	11
Dysbiosis	2	11
Advanced Glycation End products (AGE)	1	10
Aging Skin	1	10
Allergic Rhinitis	1	10
Anxiety Disorders	1	10
Bacterial Prostatitis	1	10
Candidiasis: Vulvovaginal	1	10
Chronic Kidney Disease (CKD)	1	10
Chronic Pelvic Pain Syndrome	1	10
Diarrhea	1	10
Dysmenorrhea	1	10
Fatigue	1	10
Gingivitis	1	10
Gulf War Syndrome	1	10
Incontinence: Urinary	1	10
Lipopolysaccharide-Induced Toxicity	8	10
Low Back Pain	1	10
Menstrual Cramps	1	10
Muscle Damage: Exercise-Induced	1	10
Pelvic Floor Dysfunction (PFD)	1	10
Pregnancy Complications	1	10
Prostatitis: Acute	1	10
Sinusitis	1	10
Stroke	1	10
Tendinopathy	1	10
Thyroid Diseases	1	10
Urinary Tract Infections	1	10
Cancer Metastasis	3	8
Bladder Cancer	3	7
Rheumatoid Arthritis	4	7
Inflammatory Bowel Diseases	6	6
Pseudomonas aeruginosa	4	6
Breast Cancer: Triple Negative	4	5
Colorectal Cancer	4	5
Endometriosis	2	5
Neurodegenerative Diseases	4	5
Parkinson's Disease	3	5
Radiation	2	5
Acetaminophen (Tylenol) Toxicity	2	4
Chemotherapy-Induced Toxicity: Doxorubicin	2	4
Colon Cancer	3	4
Gastric Ulcer	2	4
Hyperglycemia	3	4
Hypothyroidism	2	4
Kidney Damage	2	4
Liver Cancer	4	4
Liver Damage: Drug-Induced	2	4
Myocardial Infarction	2	4
Neuropathic Pain	2	4
Autoimmune Diseases	1	3
Blepharospasm	1	3
Brain: Oxidative Stress	2	3
Cancer: Fatigue	1	3
Colitis	2	3
Escherichia coli Infections	3	3
Lung Cancer	3	3
Melanoma	2	3
Pancreatic Cancer	2	3
Staphylococcus aureus: Methicillin-resistant (MRSA)	1	3
Alcoholic Liver Disease	1	2
Allodynia	1	2
Aluminum Toxicity	1	2
Atopic Dermatitis	1	2
Bisphenol Toxicity	1	2
Candida Albicans	2	2
Cerebral Ischemia	1	2
Chemically-Induced Liver Damage	1	2
Chemotherapy-Induced Toxicity: Cyclophosphamide	1	2
Colon Cancer: Prevention	1	2
Cystitis	1	2
Cystitis: Interstitial	1	2
Diabetes: Cognitive Dysfunction	1	2
Diabetic Ulcer	1	2
Drug Toxicity: Methotrexate	1	2
Endothelial Dysfunction	1	2
Hepatic Steatosis	1	2
Hypertension	1	2
Hypoxia	1	2
Intestinal Polyps	1	2
Kidney Stones	1	2
Learning disorders	1	2
Memory Disorders: Drug-Induced	1	2
Mobile Phone-Induced Oxidative Stress	1	2
Multiple Sclerosis	2	2
Myocarditis: Autoimmune	1	2
Painful Bladder Syndrome	1	2
Pulmonary Fibrosis: Bleomycin-Induced	1	2
Sciatic Nerve Crush Injury	1	2
Sleep Disorders	1	2
Staphylococcus aureus infection	2	2
Stress	1	2
Aspergillosis	1	1
Bacillus Cereus infection	1	1
Bacterial Infections	1	1
Cachexia: Cancer	1	1
Cancers: Drug Resistant	1	1
Coronavirus Disease (Covid-19)	1	1
Coxsackievirus Infections	1	1
Crohn's Disease	1	1
DNA damage	1	1
Diabetes Mellitus: Type 1	1	1
Edema	1	1
Enterococcus Infections	1	1
Esophageal Cancer	1	1
Fibrosarcoma	1	1
Gastric Cancer	1	1
Glioblastoma	1	1
Glioma	1	1
HIV Infections	1	1
Head and Neck Cancer	1	1
Herpes Simplex Virus Type 1	1	1
Hyperlipidemia	1	1
Influenza	1	1
Leishmaniasis	1	1
Liver Damage	1	1
Lung Inflammation	1	1
Metabolic Syndrome X	1	1
Multiple Myeloma	1	1
Musculoskeletal Diseases	1	1
Porphyromonas gingivalis	1	1
Prostate Cancer	1	1
Protozoan Infections	1	1
Respiratory Infections	1	1
Rhinovirus Infection	1	1
Staphylococcus epidermidis	1	1

Name	AC	CK
Anti-Inflammatory Agents	91	328
Analgesics	16	126
Neuroprotective Agents	34	115
Antioxidants	34	76
Tumor Necrosis Factor (TNF) Alpha Inhibitor	18	45
Interleukin-6 Downregulation	16	41
Osteoprotective	8	39
Apoptotic	20	34
Cyclooxygenase 2 Inhibitors	11	33
Interleukin-1 beta downregulation	11	27
Antiproliferative	17	25
Chemotherapeutic	5	23
Anti-Bacterial Agents	8	21
5-lipoxygenase Inhibitor	7	17
Cell cycle arrest	7	15
Hepatoprotective	8	15
Interleukin-8 downregulation	4	15
Radioprotective	3	15
Anti-Apoptotic	9	13
Brain-derived neurotrophic factor modulator	2	12
Hypoglycemic Agents	2	12
Anti-Asthmatic Agents	2	11
Antidiarrheals	2	11
Antinoceceptive	2	11
Hypolipidemic	2	11
Matrix metalloproteinase-3 (MMP-3) inhibitor	2	11
Postaglandin PGE2 downregulation	2	11
Anti-Allergic Agents	1	10
Antifungal Agents	1	10
NF-kappaB Inhibitor	8	10
Photoprotective	1	10
Cardioprotective	4	7
Chemopreventive	5	7
Nrf2 activation	4	7
Anti-metastatic	5	6
Chemoprotective Agents	3	6
Renoprotective	3	6
Anticarcinogenic Agents	4	5
Antimicrobial	5	5
Immunomodulatory	2	5
Anti-Fibrotic	2	4
Antiviral Agents	4	4
Heme oxygenase-1 up-regulation	2	4
Malondialdehyde Down-regulation	3	4
Transforming growth factor beta (TGF-β) inhibitor	2	4
Antineoplastic Agents	3	3
Bcl-2 protein down-regulation	2	3
Nitric Oxide Inhibitor	2	3
Acetylcholinesterase Inhibitor	1	2
Anti-Ulcer Agents	1	2
Enzyme Inhibitors	1	2
Gastrointestinal Agents	2	2
Gastroprotective	1	2
Gluconeogenesis Inhibitor	1	2
Interferon Gamma Reducer	1	2
Interleukin-10 downregulation	1	2
Interleukin-12 downregulation	1	2
Interleukin-2 Downregulation	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	2	2
Matrix metalloproteinase-9 (MMP-9) inhibitor	2	2
Regenerative	1	2
Vasoprotective	1	2
Alpha-glucosidase inhibitor	1	1
Anti-Cachexic Agents	1	1
Antidepressive Agents	1	1
Antihypertensive Agents	1	1
Antiprotozoal Agents	1	1
Chemosensitizer	1	1
Chondroprotective	1	1
Cyclooxygenase 1 Inhibitor	1	1
Cytotoxic	1	1
Immunostimulatory	1	1
Interferon-gamma (IFN-gamma) inducer	1	1
Interleukin-17 downregulation	1	1
Leishmanicidal	1	1
MicroRNA modulator	1	1
Prostaglandin PGE2 downregulation	1	1
Reverse Transcriptase Inhibitors	1	1
STAT3 Inhibitor	1	1
Superoxide Dismutase Up-regulation	1	1
Vascular Endothelial Growth Factor Inhibitors	1	1
Wnt/β-catenin signaling pathway modulation	1	1

Additional Keywords : Plant Extracts

[+]

A formulation containing Frankincense and Turmeric extracts demonstrated a greater improvement in the treatment of OA than celecoxib.Oct 31, 2013

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Pubmed Data : Mol Med Rep. 2013 Nov ;8(5):1542-8. Epub 2013 Aug 29. PMID: 24002213

Article Published Date : Oct 31, 2013

Study Type : Human Study

Additional Links

Substances : Frankincense, Turmeric

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors

Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs

Problem Substances : Celecoxib, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

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A Frankincense extract attenuates the symptoms associated with mild Ulcerative Colitis in remission.May 31, 2016

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Pubmed Data : Nutrients. 2022 Jan 18 ;14(3). Epub 2022 Jan 18. PMID: 35276778

Article Published Date : Jan 17, 2022

Study Type : Human Study

Additional Links

Substances : Curcumin, Frankincense

Diseases : Dysbiosis, Irritable Bowel Syndrome

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

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Benefits of a food supplement containing Boswellia serrata and bromelain for improving the quality of life in patients with osteoarthritis.Oct 31, 2019

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Pubmed Data : J Altern Complement Med. 2019 Nov 1. Epub 2019 Nov 1. PMID: 31674795

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Pubmed Data : Phytomedicine. 2003 Jan ;10(1):3-7. PMID: 12622457

Article Published Date : Dec 31, 2002

Study Type : Human Study

Additional Links

Substances : Frankincense

Diseases : Arthritis, Osteoarthritis: Knee

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents

Additional Keywords : Phytotherapy, Plant Extracts

Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

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Boswellia serrata extract shows cognitive benefits.Apr 05, 2022

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Pubmed Data : Brain Inj. 2022 Apr 6:1-7. Epub 2022 Apr 6. PMID: 35385330

Article Published Date : Apr 05, 2022

Study Type : Human Study

Additional Links

Substances : Frankincense

Diseases : Traumatic Brain Injury

Pharmacological Actions : Neuroprotective Agents

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Boswellia serrata significantly increased the pain threshold and pain tolerance force and time compared to baseline and placebo.Aug 31, 2014

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Pubmed Data : Indian J Pharmacol. 2014 Sep-Oct;46(5):475-9. PMID: 25298573

Article Published Date : Aug 31, 2014

Study Type : Human Study

Additional Links

Substances : Frankincense

Diseases : Pain

Pharmacological Actions : Analgesics, Antinoceceptive

Additional Keywords : Plant Extracts

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Boswellia serrata significantly reduced cerebral edema measured by MRI in the study population.Aug 14, 2011

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Pubmed Data : Cancer. 2011 Aug 15 ;117(16):3788-95. Epub 2011 Feb 1. PMID: 21287538

Article Published Date : Aug 14, 2011

Study Type : Human Study

Additional Links

Substances : Frankincense

Diseases : Brain Edema, Cancers: All

Therapeutic Actions : Placebo Effect

Additional Keywords : Medication Reduction, Phytotherapy

Problem Substances : Dexamethasone, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

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Boswellia topical formulation had a burn wound healing effect comparable to that of the standard SSD 1% treatment.Feb 28, 2023

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Pubmed Data : Iran J Med Sci. 2023 Mar ;48(2):137-145. PMID: 36895452

Article Published Date : Feb 28, 2023

Study Type : Human Study

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Substances : Frankincense

Diseases : Wound Healing

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Boswellic acids could be used to reduce peritumoral edema associated with primary and secondary brain tumors.Dec 14, 2011

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Pubmed Data : J Pharm Biomed Anal. 2011 Dec 15 ;56(5):998-1005. Epub 2011 Jul 29. PMID: 21855244

Article Published Date : Dec 14, 2011

Study Type : Human Study

Additional Links

Substances : Frankincense

Diseases : Brain Edema, Brain Inflammation

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

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Boswellic acids improve clinical cognitive scores and reduce systemic inflammation.Dec 31, 2022

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Pubmed Data : J Alzheimers Dis. 2023 ;94(1):359-370. PMID: 37248896

Article Published Date : Dec 31, 2022

Study Type : Human Study

Additional Links

Substances : Frankincense

Diseases : Alzheimer's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

C. longa and B. serrata resin can relieve symptoms in patients with hand osteoarthritis.Nov 30, 2022

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Pubmed Data : Pharm Biol. 2022 Dec ;60(1):2295-2299. PMID: 36416059

Article Published Date : Nov 30, 2022

Study Type : Human Study

Additional Links

Substances : Curcumin, Frankincense

Diseases : Osteoarthritis

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Medication Reduction, Plant Extracts

[+]

Casperome supplementation could represent a promising alternative approach to manage symptoms associated with IBS.Apr 30, 2017

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Pubmed Data : Drug Metab Pers Ther. 2020 Jun 8. Epub 2020 Jun 8. PMID: 32549135

Article Published Date : Jun 07, 2020

Study Type : Human Study

Additional Links

Substances : Frankincense

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents

[+]

Effect of a Boswellia and ginger mixture on the memory dysfunction of the mild traumatic brain injury patients.Dec 31, 2021

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Pubmed Data : BMC Res Notes. 2023 Mar 4 ;16(1):28. Epub 2023 Mar 4. PMID: 36869332

Article Published Date : Mar 03, 2023

Study Type : Human Study

Additional Links

Substances : Frankincense

Diseases : Osteoarthritis: Knee

Additional Keywords : Plant Extracts

[+]

Fast pain relief in exercise-induced acute musculoskeletal pain by turmeric-boswellia formulation.Sep 01, 2022

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Pubmed Data : Medicine (Baltimore). 2022 Sep 2 ;101(35):e30144. PMID: 36107505

Article Published Date : Sep 01, 2022

Study Type : Human Study

Additional Links

Substances : Frankincense, Turmeric

Diseases : Muscle Damage: Exercise-Induced

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

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Interference with catG could explain some of the anti-inflammatory properties of frankincense.Aug 31, 2009

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Pubmed Data : J Immunol. 2009 Sep 1 ;183(5):3433-42. Epub 2009 Jul 31. PMID: 19648270

Pubmed Data : Arch Gerontol Geriatr. 2018 Mar - Apr;75:146-150. Epub 2017 Dec 28. PMID: 29306113

Article Published Date : Mar 31, 2018

Study Type : Human Study

Additional Links

Substances : Frankincense, Lemon Balm

Diseases : Cognitive Decline/Dysfunction, Memory Disorders

Pharmacological Actions : Neuroprotective Agents

[+]

The combination of boswellia, turmeric, and red algae extracts tested could improve knee osteoarthritis patients.Dec 31, 2020

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Pubmed Data : Open Access Rheumatol. 2021 ;13:1-13. Epub 2021 Jan 8. PMID: 33447100

Article Published Date : Dec 31, 2020

Study Type : Human Study

Additional Links

Substances : Frankincense, Red Marine Algae, Turmeric

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Analgesics

[+]

The effects of massage with frankincense and myrrh oil in chronic low back pain.Dec 31, 2022

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Pubmed Data : Explore (NY). 2023 ;19(5):761-767. Epub 2023 Apr 14. PMID: 37121835

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Pubmed Data : Am J Ophthalmol Case Rep. 2023 Jun ;30:101848. Epub 2023 Apr 11. PMID: 37252049

Article Published Date : May 31, 2023

Study Type : Human: Case Report

Additional Links

Substances : Frankincense

Diseases : Blepharospasm

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Essential Oils

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This article describes one patient's experience using frankincense (Boswellia carterii) essential oil to help in the management of her fatigue.Dec 31, 2017

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Pubmed Data : Asian Pac J Trop Med. 2014 Sep ;7S1:S485-90. PMID: 25312172

Article Published Date : Aug 31, 2014

Study Type : Animal Study

Additional Links

Substances : Frankincense

Diseases : Arthritis, Inflammation

Pharmacological Actions : Analgesics

[+]

Anti-inflammatory and -apoptotic effects of a long-term herbal extract treatment on DSS-induced colitis.Aug 10, 2021

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Pubmed Data : Mol Biol Rep. 2022 Aug ;49(8):7425-7435. Epub 2022 Jun 18. PMID: 35716287

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Boswellic acids, pentacyclic triterpenes, attenuate oxidative stress, and bladder tssue damage in cyclophosphamide-induced cystitis.Apr 25, 2022

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Pubmed Data : J Diabetes Metab Disord. 2020 Jun ;19(1):153-162. Epub 2020 Feb 25. PMID: 32550165

Article Published Date : May 31, 2020

Study Type : Animal Study

Additional Links

Substances : Frankincense

Diseases : Hyperglycemia

Pharmacological Actions : Hepatoprotective, Hypoglycemic Agents, Renoprotective

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Effects of Boswellia serrata resin extract on motor dysfunction and brain oxidative stress in an experimental model of Parkinson's disease.Apr 30, 2019

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Pubmed Data : Avicenna J Phytomed. 2019 May-Jun;9(3):281-290. PMID: 31143695

Article Published Date : Apr 30, 2019

Study Type : Animal Study

Additional Links

Substances : Frankincense

Diseases : Brain: Oxidative Stress, Parkinson's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

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Pharmacological Actions : Antioxidants

Additional Keywords : Essential Oils

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Frankincense essential oil from Boswellia sacra is capable of suppressing viability and inducing apoptosis in pancreatic cancer cell lines.Dec 31, 2011

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Pubmed Data : BMC Complement Altern Med. 2012 ;12:253. Epub 2012 Dec 13. PMID: 23237355

Article Published Date : Dec 31, 2011

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Frankincense

Diseases : Pancreatic Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Plant Extracts

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Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity.May 27, 2019

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Pubmed Data : Oncotarget. 2019 May 28 ;10(37):3472-3490. Epub 2019 May 28. PMID: 31191820

Article Published Date : May 27, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Frankincense

Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage: Drug-Induced, Melanoma

Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Hepatoprotective

Additional Keywords : Essential Oils

Problem Substances : Acetaminophen

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Frankincense extract is able to promote sciatic nerve regeneration and improve the function of a crushed sciatic nerve.Dec 31, 2015

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Pubmed Data : Phytomedicine. 2023 Jan ;108:154540. Epub 2022 Nov 12. PMID: 36379093

Article Published Date : Dec 31, 2022

Study Type : Animal Study

Additional Links

Substances : Frankincense, Myrrh

Diseases : Neuropathic Pain

Pharmacological Actions : Anti-Inflammatory Agents

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Long-term effects of a diet supplement containing Cannabis sativa oil and Boswellia serrata in dogs with osteoarthritis.Sep 05, 2022

Pubmed Data : Planta Med. 2021 Jun 11. Epub 2021 Jun 11. PMID: 34116571

Article Published Date : Jun 10, 2021

Study Type : Animal Study

Additional Links

Substances : Frankincense

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Protective effect of boswellic acids against doxorubicin-induced hepatotoxicity.Dec 31, 2017

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Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:8296451. Epub 2018 Feb 6. PMID: 29541348

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Pubmed Data : Life Sci. 2022 Jul 19 ;306:120799. Epub 2022 Jul 19. PMID: 35863426

Article Published Date : Jul 18, 2022

Study Type : Animal Study

Additional Links

Substances : Frankincense

Diseases : Kidney Damage

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Silymarin, boswellic acid and curcumin enriched dietetic formulation reduces the growth of inherited intestinal polyps.Apr 13, 2020

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Pubmed Data : World J Gastroenterol. 2020 Apr 14 ;26(14):1601-1612. PMID: 32327909

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Pubmed Data : Avicenna J Phytomed. 2016 Jul-Aug;6(4):468-75. PMID: 27516988

Article Published Date : Jun 30, 2016

Study Type : Animal Study

Additional Links

Substances : Frankincense

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

These findings support that boswellic acid is a potent hepato-protective agent.May 31, 2017

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Pubmed Data : Biomedicine (Taipei). 2017 Jun ;7(2):13. Epub 2017 Jun 14. PMID: 28612711

Article Published Date : May 31, 2017

Study Type : Animal Study

Additional Links

Substances : Frankincense

Diseases : Acetaminophen (Tylenol) Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective

Problem Substances : Acetaminophen, Paracetamol

[+]

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Pubmed Data : Front Pharmacol. 2020 ;11:744. Epub 2020 May 15. PMID: 32499711

Article Published Date : Dec 31, 2019

Study Type : Review

Additional Links

Substances : Curcumin, Frankincense, Licorice, Lion's Mane (Hericium Erinaceus), Medicinal Mushrooms, Reishi Mushroom

Diseases : Bladder Cancer, Breast Cancer, Cancers: All, Colitis, Dysbiosis, Esophageal Cancer, Lung Cancer

Pharmacological Actions : Anticarcinogenic Agents, Apoptotic, Chemopreventive, Gastrointestinal Agents

[+]

A review of the role of dietary supplements in inflammatory bowel disease.Nov 30, 2016

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Pubmed Data : Eur J Gastroenterol Hepatol. 2016 Dec ;28(12):1357-1364. PMID: 27769076

Article Published Date : Nov 30, 2016

Study Type : Review

Additional Links

Substances : Curcumin, Folic Acid , Frankincense, Green Tea, Probiotics, Vitamin B-12, Vitamin D

Diseases : Inflammatory Bowel Diseases

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Pubmed Data : Fitoterapia. 2021 Nov ;155:105064. Epub 2021 Oct 14. PMID: 34656670

Article Published Date : Oct 31, 2021

Study Type : In Vitro Study

Additional Links

Substances : Frankincense

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Liver Damage

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective

[+]

Anti-osteoarthritic effects of an herbal composition LI73014F2 on interleukin-1β-induced primary human articular chondrocytes. Apr 26, 2020

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Pubmed Data : Molecules. 2020 Apr 27 ;25(9). Epub 2020 Apr 27. PMID: 32349389

Article Published Date : Apr 26, 2020

Study Type : In Vitro Study

Additional Links

Substances : Frankincense, Terminalia chebula, Turmeric

Diseases : Osteoarthritis

Pharmacological Actions : 5-Lipoxygenase Inhibitor, Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Antibacterial activity of Boswellia sacra extract against Porphyromonas gingivalis periodontal pathogen.Jul 14, 2021

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Pubmed Data : Prostaglandins Other Lipid Mediat. 2017 May 24 ;131:1-8. Epub 2017 May 24. PMID: 28549801

Article Published Date : May 23, 2017

Study Type : In Vitro Study

Additional Links

Substances : Frankincense

Diseases : Colon Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Prostaglandin PGE2 downregulation, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Plant Extracts

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Binding of boswellic acids to functional proteins of the SARS-CoV-2 virus: Bioinformatic studies.Oct 31, 2021

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Pubmed Data : Cancer Biol Ther. 2012 May ;13(7):542-52. Epub 2012 May 1. PMID: 22415137

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Pubmed Data : J Ethnopharmacol. 2016 Jun 21. Epub 2016 Jun 21. PMID: 27346540

Article Published Date : Jun 20, 2016

Study Type : In Vitro Study

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Substances : Frankincense

Diseases : Cancers: All

Pharmacological Actions : Apoptotic

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Boswellic acids as effective antibacterial antibiofilm agents. Jun 12, 2022

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Pubmed Data : Molecules. 2022 Jun 13 ;27(12). Epub 2022 Jun 13. PMID: 35744925

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Pubmed Data : Biochem Pharmacol. 2012 Jan 1 ;83(1):115-21. Epub 2011 Oct 5. PMID: 22001311

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Pubmed Data : J Chromatogr A. 2012 Oct 26 ;1261:158-63. Epub 2012 Jun 28. PMID: 22835693

Article Published Date : Oct 25, 2012

Study Type : Plant Study

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Substances : Frankincense

Additional Keywords : Cultivars, Essential Oils

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Chloroform extract and acetyl-11-keto-beta-boswellic acid from Boswellia dalzielii stem bark induce apoptosis and cell cycle blockage in AW8507 cells.Aug 08, 2021

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Pubmed Data : J Egypt Natl Canc Inst. 2021 Aug 9 ;33(1):20. Epub 2021 Aug 9. PMID: 34368899

Article Published Date : Aug 08, 2021

Study Type : In Vitro Study

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Substances : acetyl-11-keto-beta-boswellic acid, Frankincense

Diseases : Head and Neck Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Plant Extracts

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Composition and potential anticancer activities of essential oils obtained from myrrh and frankincense.Sep 30, 2013

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View the Evidence: 227 Abstracts with Frankincense Research

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Boswellia and its extract may be an effective and safe treatment option for patient with osteoarthritis.Jul 16, 2020

4 weeks of frankincense consumption facilitates the acquisition and retention of motor memory in older men with moderate mental status.Jan 07, 2019

A Boswellia-based cream could be used for prevention of adjuvant radiotherapy skin damage in mammary carcinoma.Mar 31, 2015

A formulation containing Frankincense and Turmeric extracts demonstrated a greater improvement in the treatment of OA than celecoxib.Oct 31, 2013

A Frankincense extract attenuates the symptoms associated with mild Ulcerative Colitis in remission.May 31, 2016

A herbal formulation is a safe and effective intervention for management of joint discomfort.Apr 30, 2018

A pilot study to examine the effects of an anti-inflammatory supplement on eicosanoid derivatives in patients with chronic kidney disease.Jul 31, 2017

A standardised frankincense extract reduces disease activity in relapsing-remitting multiple sclerosis.Dec 31, 2017

A supplement with Ribes Nigrum, Boswellia Serrata, bromelain and vitamin D to stop local inflammation in chronic sinusitis.Apr 17, 2023

Administration of Boswellia serrate extract with a high fat meal boosted boswellic acid levels. Nov 30, 2004

Aflapin exhibited better efficacy compared to 5-Loxin to reduce pain and improve physical functions significantly in OA subjects.Dec 31, 2009

Aromatherapy blend of thyme, orange, clove bud, and frankincense boosts energy levels in post-COVID-19 female patients.Mar 23, 2022

Ayurvedic medicine offers a good alternative to glucosamine and celecoxib in the treatment of symptomatic knee osteoarthritis.Jul 31, 2013

Beneficial effects on abdominal bloating with an innovative food-grade formulation of Curcuma longa and Boswellia serrata extracts in subjects with irritable bowel syndrome.Jan 17, 2022

Benefits of a food supplement containing Boswellia serrata and bromelain for improving the quality of life in patients with osteoarthritis.Oct 31, 2019

Boswellia resin extract and propolis derived polyphenols can reduce genitourinary pain and then improve quality of life of men affected by prostatitis-like symptoms.Jan 13, 2020

Boswellia resin extract and propolis derived polyphenols in patients with type III chronic prostatitis/chronic pelvic pain syndrome.Mar 31, 2022

Boswellia serrata Extract could be recommended in patients of osteoarthritis of the knee with possible therapeutic use in other arthritis.Dec 31, 2002

Boswellia serrata extract shows cognitive benefits.Apr 05, 2022

Boswellia serrata significantly increased the pain threshold and pain tolerance force and time compared to baseline and placebo.Aug 31, 2014

Boswellia serrata significantly reduced cerebral edema measured by MRI in the study population.Aug 14, 2011

Boswellia topical formulation had a burn wound healing effect comparable to that of the standard SSD 1% treatment.Feb 28, 2023

Boswellic acids could be used to reduce peritumoral edema associated with primary and secondary brain tumors.Dec 14, 2011

Boswellic acids improve clinical cognitive scores and reduce systemic inflammation.Dec 31, 2022

C. longa and B. serrata resin can relieve symptoms in patients with hand osteoarthritis.Nov 30, 2022

Casperome supplementation could represent a promising alternative approach to manage symptoms associated with IBS.Apr 30, 2017

Constitutes of Boswellia serrata extract act synergistically to exert anti-inflammatory/anti-arthritic activity.Mar 05, 2019

Curcumin and Boswellia serrate has beneficial effects on glycoxidation and lipid peroxidation in chronically exercising master athletes.Nov 20, 2016

Curcuminoids and boswellia serrata extracts combination decreases tendinopathy symptoms.Dec 06, 2020

Differentially enhancing effects of long-term treatment with serrazyme, boswellia and pine on seminal bacterial detection in patients with chronic bacterial or inflammatory prostatitis.Dec 31, 2017

Double-blind trial of solid lipid Boswellia serrata particles vs. standardized Boswellia serrata gum extract for osteoarthritis of knee. Jun 07, 2020

Effect of a Boswellia and ginger mixture on the memory dysfunction of the mild traumatic brain injury patients.Dec 31, 2021

Efficacy of Boswellia serrata extract and/or an omega-3-based product for improving pain and function in people older than 40 years with persistent knee pain.Sep 02, 2023

Efficacy of Boswellia serrata L. and Cyperus scariosus L. plus pelvic floor muscle training in stress incontinence in women.Oct 31, 2014

Efficacy of frankincense-based herbal product in urinary incontinence.Nov 27, 2022

Episiotomy wound healing by Commiphora myrrha and Boswellia carteri in primiparous women.Sep 20, 2020

Essential oil hand massage was used with hospice patients with terminal cancer with a positive effect on pain and depression.Jul 31, 2008

Evaluation of the effectiveness of topical oily solution containing frankincense extract in the treatment of knee osteoarthritis.Mar 03, 2023

Fast pain relief in exercise-induced acute musculoskeletal pain by turmeric-boswellia formulation.Sep 01, 2022

Frankincense may be feasibly applied to improve inflammation based disease of gingival as an adjunct to the conventional mechanical therapy.Dec 31, 2010

Functional improvement and immune-inflammatory cytokines profile of ischaemic stroke patients after treatment with boswellic acids.Nov 30, 2019

Inhalation of aromatherapy essential oil may have potential as an effective intervention to alleviate perennial allergic rhinitis.Dec 31, 2015

Interference with catG could explain some of the anti-inflammatory properties of frankincense.Aug 31, 2009

L-Methionine associated with Hibiscus sabdariffa and Boswellia serrata extracts for symptoms relief in patients affected by recurrent uncomplicated urinary tract infections.Jun 29, 2018

Lipid mediator profiles predict response to therapy with an oral frankincense extract in relapsing-remitting multiple sclerosis.May 28, 2020

Methylsulfonylmethane and boswellic acids versus glucosamine sulfate in the treatment of knee arthritisFeb 29, 2016

Olibanum gum resin could be used as a safe anti-oxidant, anti-hyperglycemic and anti-hyperlipidemic agent for type 2 diabetic patients.Dec 31, 2013

Positive effects of a lecithin-based delivery form of Boswellia serrata extract in acute diarrhea of adult subjects.Apr 28, 2022

Supplementation with Boswellia had beneficial effects on pain, stiffness and physical functions in patients with symptomatic knee osteoarthritis.Nov 30, 2014

The Boswellia serrate and lemon balm tablet in older adults can be beneficial on improvement of memory.Mar 31, 2018

The combination of boswellia, turmeric, and red algae extracts tested could improve knee osteoarthritis patients.Dec 31, 2020

The effects of massage with frankincense and myrrh oil in chronic low back pain.Dec 31, 2022

The efficacy of Kundur (Boswellia serrata Roxb. Ex Colebr.) in Vulvovaginal candidiasis.Jun 23, 2022

The use of Boswellia phytosome extracts are beneficial for asthmatic patients as it helps reduce the need for inhalation therapy.Sep 30, 2015

These preliminary results indicate the efficacy and safety of Movardol supplementation in the management of moderate knee osteoarthritis.Nov 30, 2016

This study provides preliminary evidence that curcumin and maritime pine may help alleviate symptoms of Gulf War Illness.Jan 02, 2021

Topical application of boswellic acids may represent a suitable treatment option for selected features of skin photoaging.Dec 31, 2009

Treatment for benign thyroid nodules with a combination of natural extracts.Aug 31, 2019

Turmeric-boswellia-sesame formulation exhibited remarkable menstrual pain relief as compared to the placebo.Jun 10, 2023

Twelve-week use of curcumin complex or its combination with boswellic acid reduces pain-related symptoms in patients with osteoarthritis.Jan 08, 2018

Use of an alfa-lipoic, Methylsulfonylmethane, Boswellia serrata and Bromelain dietary supplement (OPERA®) for aromatase inhibitors-related arthralgia management.Jun 05, 2022

Human bladder cancer cells and immortalized normal bladder cells were studied using Frankincense oil; Frankincense oil appears to distinguish cancerous from normal bladder cells and suppress cancer cell viability. Dec 31, 2008

This study compares Boswellia sacra essential oil hydrodistilled at 100 °C vs 78 °C in inducing cancer cell death in cultured breast cancer cells; the oil prepared at 100 °C was more potent in inducing breast cancer cell-specific cytotoxicity.Dec 31, 2010

Antibacterial effects of frankincense oil and its interaction with some antibiotics against multidrug-resistant pathogens.Nov 09, 2022

Boswellia serrata enhances passive range-of-motion exercises in radiation-induced trismus.Mar 31, 2024

Effect of extract from Boswellia serrata gum resin on decrease of GAD65 autoantibodies in a patient with latent autoimmune diabetes in adults.Jul 14, 2020

Evaluation of antibacterial and wound-healing activities of alcoholic extract of Boswellia carterii, in vitro and in vivo study.Jun 30, 2022

Frankincense ameliorates endometriosis via inducing apoptosis and reducing adhesion.May 31, 2023

Possible role of frankincense in the treatment of benign essential blepharospasm.May 31, 2023

This article describes one patient's experience using frankincense (Boswellia carterii) essential oil to help in the management of her fatigue.Dec 31, 2017

A combined water extract of frankincense and myrrh alleviates neuropathic pain. Dec 31, 2016

A frankincense extract displayed anti-inflammatory, anti-oxidative, and hepatoprotective effects.Dec 31, 2017

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View the Evidence:
227 Abstracts with Frankincense Research