Gallic Acid

Name	AC	CK
DNA damage	2	12
Diabetes: Oxidative Stress	2	12
Cadmium Poisoning	1	10
Diabetes Mellitus: Type 2	4	8
Inflammation	4	6
Obesity	3	6
Oxidative Stress	4	6
Diabetic Complications	3	5
Advanced Glycation End products (AGE)	2	4
Anxiety	2	4
Chemotherapy-Induced Toxicity: Cyclophosphamide	2	4
Dyslipidemias	2	4
Insulin Resistance	2	4
Liver Fibrosis	2	4
Lung Cancer	3	4
Uranium Poisoning	2	4
Alcohol Toxicity	2	3
Bisphenol Toxicity	2	3
Chemically-Induced Liver Damage	2	3
Colon Cancer	2	3
Gastrointestinal Inflammation	2	3
Heart Failure	2	3
Heavy Metal Toxicity	2	3
Liver Cancer	2	3
Melanoma	2	3
Oral Cancer	3	3
Acute Myeloid Leukemia	2	2
Air Pollution Linked Toxicity	1	2
Allergic Rhinitis	1	2
Atopic Dermatitis	1	2
Brain Inflammation	1	2
Candida Albicans	1	2
Candida Infection	2	2
Cardiomyopathy	1	2
Cervical Cancer	2	2
Cognitive Decline/Dysfunction	1	2
Colitis	1	2
Dementia: Alzheimer Type	1	2
Depression	1	2
Diabetes: Cognitive Dysfunction	1	2
Endothelial Dysfunction	1	2
Hyperglycemia	1	2
Hypertension	1	2
Influenza	1	2
Influenza A	1	2
Influenza B	1	2
Keloid	1	2
Kidney Damage: Chemically-Induced	1	2
Lipopolysaccharide-Induced Toxicity	1	2
Liver Injury: Ischemia/reperfusion	1	2
Liver Steatosis	1	2
Lymphoma	1	2
Mastocytoma	1	2
Memory Disorders	1	2
Myocardial Fibrosis	1	2
Paraquat Toxicity	1	2
Prostate Cancer	1	2
Wound Healing	1	2
Abortion: Spontaneous	1	1
Acute lymphoblastic leukemia (ALL)	1	1
Alcoholic Liver Disease	1	1
Alzheimer's Disease	1	1
Aspergillosis	1	1
Atherosclerosis	1	1
Bacterial Vaginosis	1	1
Breast Cancer	1	1
Breast Cancer: Triple Negative	1	1
Carcinoma: Non-Small-Cell Lung	1	1
Cardiovascular Diseases	1	1
Cholangiocarcinoma	1	1
Coronavirus Infection	1	1
Diabetes Mellitus: Type 1	1	1
Drug-Induced Toxicity: Gastrointestinal	1	1
Drug-Induced Toxicity: Indomethacin	1	1
Esophageal Cancer	1	1
Fatigue	1	1
Fibrosarcoma	1	1
Gastric Ulcer	1	1
Giardiasis	1	1
HIV Infections	1	1
Helicobacter Pylori Infection	1	1
Human Papillomavirus (HPV)	1	1
Leukemia	1	1
Neurodegenerative Diseases	1	1
Non-Small-Cell Lung Carcinoma	1	1
Rhinovirus Infection	1	1
Staphylococcus aureus infection	1	1
Stomach Cancer	1	1
Allergies	1	0

Name	AC	CK
Antioxidants	22	46
Anti-Inflammatory Agents	16	37
Apoptotic	16	18
Antiproliferative	11	14
Neuroprotective Agents	7	12
Interleukin-6 Downregulation	6	11
Tumor Necrosis Factor (TNF) Alpha Inhibitor	6	11
Hepatoprotective	5	8
Hypoglycemic Agents	4	8
Anti-Fibrotic	4	7
Cardioprotective	4	6
Renoprotective	3	6
MicroRNA modulator	3	5
Antineoplastic Agents	4	4
Antiviral Agents	3	4
Cell cycle arrest	3	4
Chemopreventive	3	4
Hypolipidemic	2	4
Insulin Sensitizers	2	4
Chemotherapeutic	3	3
Immunomodulatory	2	3
Adiponectin upregulation	1	2
Anti-Anxiety Agents	1	2
Anti-metastatic	1	2
Anticarcinogenic Agents	1	2
Anticholesteremic Agents	1	2
Antidepressive Agents	1	2
Antifungal Agents	1	2
Antihypertensive Agents	1	2
Bcl-2 protein down-regulation	2	2
Brain-derived neurotrophic factor modulator	1	2
Chelating Agents	1	2
Chemoprotective Agents	1	2
Chemosensitizer	2	2
Cyclooxygenase 2 Inhibitors	1	2
Cytoprotective	1	2
Gastroprotective	2	2
Genoprotective	1	2
Immunomodulatory: Th17 downregulation	1	2
Interleukin-1 beta downregulation	1	2
Interleukin-4 downregulation	1	2
Interleukin-5 downregulation	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	2	2
Matrix metalloproteinase-9 (MMP-9) inhibitor	2	2
Tumor Suppressor Protein p53 Upregulation	2	2
interleukin-13 down-regulation	1	2
Anti-Bacterial Agents	1	1
Anti-Ulcer Agents	1	1
Antigiardial agents	1	1
Antimicrobial	1	1
Antiparasitic Agents	1	1
Cytotoxic	1	1
Enzyme Activators	1	1
Enzyme Inhibitors	1	1
HIV Protease Inhibitors	1	1
Insulin-releasing	1	1
NF-kappaB Inhibitor	1	1
Nitric Oxide Inhibitor	1	1
Nrf2 activation	1	1
P21 Activation	1	1
Prostaglandin PGE2 downregulation	1	1
Reverse Transcriptase Inhibitors	1	1

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Gallic acid diminishes pro-inflammatory interferon-γ- and interleukin-17-producing sub-populations in vitro in patients with psoriasis.May 31, 2023

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Antidiabetic potential of gallic acid from Emblica officinalis.Mar 31, 2019

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Pubmed Data : Phytomedicine. 2019 Apr 1:152906. Epub 2019 Apr 1. PMID: 31064680

Article Published Date : Mar 31, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Gallic Acid, Indian Gooseberry

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Anticholesteremic Agents, Antihypertensive Agents, Hypoglycemic Agents, Insulin Sensitizers

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Antifibrotic effects of gallic acid on hepatic stellate cells.Dec 31, 2018

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Pubmed Data : J Tradit Complement Med. 2019 Jan ;9(1):45-53. Epub 2018 Apr 27. PMID: 30671365

Article Published Date : Dec 31, 2018

Study Type : Animal Study, In Vitro Study

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Substances : Gallic Acid

Diseases : Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic

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Antioxidant, anti-inflammatory and protective potential of gallic acid against paraquat-induced liver toxicity in male rats.Oct 31, 2021

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Pubmed Data : Chemosphere. 2021 May ;270:128659. Epub 2020 Oct 19. PMID: 33757277

Article Published Date : Apr 30, 2021

Study Type : Animal Study

Additional Links

Substances : Gallic Acid, Moringa oleifera

Diseases : Heavy Metal Toxicity

Pharmacological Actions : Antioxidants, Chelating Agents

Additional Keywords : Plant Extracts

Problem Substances : Cadmium, Lead

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Gall of Quercus brantii is able to exert antioxidative and anti-inflammatory effects on the biochemical and pathological parameters of colitis.Dec 21, 2014

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Pubmed Data : Drug Chem Toxicol. 2019 Mar 25:1-12. Epub 2019 Mar 25. PMID: 30907158

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Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2020 Jul 30. Epub 2020 Jul 30. PMID: 32734364

Article Published Date : Jul 29, 2020

Study Type : Animal Study

Additional Links

Substances : Gallic Acid

Diseases : Kidney Damage: Chemically-Induced, Paraquat Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Renoprotective

Problem Substances : Paraquat

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Gallic acid improves uranium detoxification in animals exposed to uranium. Jan 01, 1990

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Pubmed Data : Fundam Appl Toxicol. 1990 Jan;14(1):88-95. PMID: 2307325

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Pubmed Data : Sci Rep. 2017 Nov 15 ;7(1):15607. Epub 2017 Nov 15. PMID: 29142252

Article Published Date : Nov 14, 2017

Study Type : Animal Study

Additional Links

Substances : Gallic Acid

Diseases : Hypertension

Pharmacological Actions : Antioxidants

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Pubmed Data : Eur J Nutr. 2018 Jul 23. Epub 2018 Jul 23. PMID: 30039436

Article Published Date : Jul 22, 2018

Study Type : Animal Study

Additional Links

Substances : Gallic Acid

Diseases : DNA damage, Obesity

Pharmacological Actions : Genoprotective, Hypoglycemic Agents

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Gallic acid protects particulate matter (PM10) triggers cardiac oxidative stress and inflammation causing heart adverse events in rats.Apr 29, 2019

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Pubmed Data : Environ Sci Pollut Res Int. 2019 Apr 30. Epub 2019 Apr 30. PMID: 31041709

Article Published Date : Apr 29, 2019

Study Type : Animal Study

Additional Links

Substances : Gallic Acid

Diseases : Air Pollution Linked Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Gallic and hesperidin ameliorate electrolyte imbalances in AlCl3-induced nephrotoxicity.Dec 31, 2021

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Pubmed Data : Biochem Res Int. 2022 ;2022:6151684. Epub 2022 Oct 10. PMID: 36263197

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Gallic Acid, Hesperidin

Diseases : Aluminum Toxicity , Kidney Damage: Chemically-Induced

Pharmacological Actions : Renoprotective

Problem Substances : Aluminum Chloride

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Neuroprotection by luteolin and gallic acid against cobalt chloride-induced behavioural, morphological and neurochemical alterations in Wistar rats.Dec 31, 2018

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Pubmed Data : Neurotoxicology. 2019 09 ;74:252-263. Epub 2019 Jul 27. PMID: 31362009

Protective effects of crocin and gallic acid on the liver damage.Dec 31, 2022

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Pubmed Data : Metab Brain Dis. 2018 Oct 3. Epub 2018 Oct 3. PMID: 30280285

Article Published Date : Oct 02, 2018

Study Type : Animal Study

Additional Links

Substances : Gallic Acid

Diseases : Depression

Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator

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Structure-based drug designing for potential antiviral activity of selected natural products from Ayurveda against SARS-CoV-2 spike glycoprotein and its cellular receptor.May 31, 2020

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Pubmed Data : Virusdisease. 2020 Jun ;31(2):179-193. Epub 2020 May 24. PMID: 32656311

Article Published Date : May 31, 2020

Study Type : In Vitro Study

Additional Links

Substances : Curcumin, Gallic Acid, Luteolin, Mangiferin, Naringenin , Piperine, Quercetin, Resveratrol

Diseases : Coronavirus Infection

Pharmacological Actions : Antiviral Agents

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A review of phenolic compounds as beneficial phytochemicals in pomegranate.Sep 29, 2018

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Pubmed Data : Food Chem. 2018 Sep 30 ;261:75-86. Epub 2018 Apr 13. PMID: 29739608

Article Published Date : Sep 29, 2018

Study Type : Review

Additional Links

Substances : Anthocyanins, Cinnamic acid, Cyanidin, Delphinidin, Ellagic Acid, Flavonoids, Gallic Acid, Pomegranate, Punicalagin

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Addition of gallic acid overcomes resistance to cisplatin in ovarian cancer cell lines.Jul 31, 2022

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Pubmed Data : Asian Pac J Cancer Prev. 2022 Aug 1 ;23(8):2661-2669. Epub 2022 Aug 1. PMID: 36037120

Article Published Date : Jul 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : Gallic Acid

Diseases : Cancers: Drug Resistant, Ovarian Cancer

Pharmacological Actions : Apoptotic, Chemosensitizer

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Anti-Helicobacter pylori and antiulcerogenic activities of the root cortex of Paeonia suffruticosa.Dec 31, 2012

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Pubmed Data : Biol Pharm Bull. 2013 ;36(10):1535-9. PMID: 24088252

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Pubmed Data : Microb Pathog. 2016 Oct ;99:56-61. Epub 2016 Aug 3. PMID: 27497894

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Pubmed Data : Food Funct. 2014 Feb ;5(2):381-9. PMID: 24413695

Article Published Date : Jan 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Anthocyanins, Gallic Acid

Diseases : Fibrosarcoma

Pharmacological Actions : Antineoplastic Agents, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

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Effect of Gallic acid in potentiating chemotherapeutic effect of paclitaxel in HeLa cervical cancer cells.Dec 31, 2018

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Pubmed Data : Invest Ophthalmol Vis Sci. 2022 Nov 1 ;63(12):12. PMID: 36350620

Article Published Date : Oct 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : Gallic Acid

Diseases : Aspergillosis

Pharmacological Actions : Anti-Inflammatory Agents, Antifungal Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Gallic acid and aqueous S. cumini leaf extract exhibited immunomodulatory properties.Sep 11, 2015

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Pubmed Data : Drug Chem Toxicol. 2015 Sep 12:1-8. Epub 2015 Sep 12. PMID: 26364973

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Pubmed Data : Toxins (Basel). 2018 Jul 3 ;10(7). Epub 2018 Jul 3. PMID: 29970790

Article Published Date : Jul 02, 2018

Study Type : In Vitro Study

Additional Links

Substances : Gallic Acid

Diseases : Aspergillosis

Pharmacological Actions : Antioxidants

Problem Substances : Aflatoxin

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Gallic acid is effective in the inhibition of proliferation and induction of apoptosis in Jurkat cell line.Oct 31, 2016

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Gallic acid restores the sulfonamide sensitivity of multidrug-resistant Streptococcus suis.May 09, 2023

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Pubmed Data : J Agric Food Chem. 2023 May 10 ;71(18):6894-6907. Epub 2023 May 1. PMID: 37125728

Article Published Date : May 09, 2023

Study Type : In Vitro Study

Additional Links

Substances : Gallic Acid

Diseases : Infection: Antibiotic Resistant, Streptococcus Infections

Pharmacological Actions : Anti-Bacterial Agents

Additional Keywords : Multidrug Resistance

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Gallic acid suppresses the progression of triple-negative breast cancer HCC1806 cells.Dec 31, 2021

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Pubmed Data : Pharm Biol. 2016 Sep ;54(9):1831-40. Epub 2016 Jan 21. PMID: 26794080

Article Published Date : Aug 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Gallic Acid, Pelargonium sidoides

Diseases : Leukemia

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs

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Polyphenol-rich extracts from strawberry, arctic bramble, blackberry, and cloudberry applied to trophozoites of Giardia duodenalis were as effective as metronidazole in causing trophozoite mortality in vitro. Aug 01, 2011

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Pubmed Data : Zhong Xi Yi Jie He Xue Bao. 2004 Jan;2(1):30-2. PMID: 16322071

Article Published Date : Jan 01, 2004

Additional Links

Substances : Gallic Acid

Diseases : Allergies

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View the Evidence: 125 Abstracts with Gallic Acid Research

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Gallic acid diminishes pro-inflammatory interferon-γ- and interleukin-17-producing sub-populations in vitro in patients with psoriasis.May 31, 2023

Gallic acid improves health associated biochemical parameters and prevents oxidative damage of DNA in type 2 diabetes patients.Nov 27, 2017

Glutathione administration with EDTA might be an effective treatment modality for patients with cadmium intoxication.Apr 22, 2010

Anti-inflammatory and antioxidative effects of gallic acid on experimental dry eye.Apr 30, 2023

Gallic acid alleviates gastric precancerous lesions through inhibition of epithelial mesenchymal transition.Feb 09, 2023

Gallic and butyric acids modulated NLRP3 inflammasome markers in a co-culture model of intestinal inflammation.Nov 30, 2020

Ameliorative effects of gallic acid on cisplatin-induced nephrotoxicity.Dec 31, 2020

Antidiabetic potential of gallic acid from Emblica officinalis.Mar 31, 2019

Antifibrotic effects of gallic acid on hepatic stellate cells.Dec 31, 2018

Antioxidant, anti-inflammatory and protective potential of gallic acid against paraquat-induced liver toxicity in male rats.Oct 31, 2021

Black raspberry seed and gallic acid show potent and broad antiviral activity against influenza A and B type viruses.Dec 31, 2015

Co-administration of antioxidant significantly increased plasma level of curcumin in animal models.Nov 25, 2015

Curcumin and gallic acid have a protective role in advanced glycation end products induces systemic inflammation and weight gain.Feb 08, 2018

Curcumin could inhibit the pro-oxidant effects of gallic acid.Dec 26, 2015

Dual actions of gallic acid and andrographolide trigger AdipoR1 to stimulate insulin secretion in a streptozotocin-induced diabetes rat model.Dec 31, 2022

Effects of Moringa oleifera leaf extracts and its bioactive compound gallic acid on reducing toxicities of heavy metals.Apr 30, 2021

Gall of Quercus brantii is able to exert antioxidative and anti-inflammatory effects on the biochemical and pathological parameters of colitis.Dec 21, 2014

Gallic acid ameliorates atherosclerosis and vascular senescence and remodels the microbiome.Aug 22, 2022

Gallic acid ameliorates atopic dermatitis-like skin inflammation through immune regulation.Dec 31, 2020

Gallic acid ameliorates sodium arsenite-induced renal and hepatic toxicity.Mar 24, 2019

Gallic acid and myricetin-rich Labisia pumila extract mitigated multiple diabetic eye disorders in rats.Oct 06, 2021

Gallic acid and p-coumaric acid attenuate type 2 diabetes-induced neurodegeneration.Dec 31, 2016

Gallic acid and p-coumaric acid exhibited marked anti-diabetic action.Aug 31, 2018

Gallic acid attenuated lipopolysaccharide-induced neuroinflammation.Dec 11, 2019

Gallic acid attenuates high-fat diet fed-streptozotocin-induced insulin resistance.Dec 14, 2014

Gallic acid can modify the reproductive toxicity of cyclophosphamide.Mar 17, 2019

Gallic acid could alleviate the noxious effects of paraquat on the antioxidant defense system and renal tissue.Jul 29, 2020

Gallic acid could be used for improving metabolic disorders such as insulin resistance and dyslipidemia.Oct 23, 2019

Gallic acid enhances detoxification in the chelation of uranium in mice. Mar 01, 1989

Gallic acid exerted protective effects against stress-induced mood and memory deficit disorders.Nov 30, 2018

Gallic acid has the capacity to protect against reproductive toxicity induced by cyclophosphamide.Jul 28, 2015

Gallic acid has the potential to be developed further as a natural antifungal agent for clinical use.May 18, 2017

Gallic acid has therapeutic potential for the treatment of heart failure-induced pulmonary fibrosis.Nov 30, 2017

Gallic acid impairs fructose-driven de novo lipogenesis and ameliorates hepatic steatosis.Dec 14, 2022

Gallic acid improves inflammation, oxidative stress and hypotension result from diabetes.Mar 31, 2019

Gallic acid improves uranium detoxification in animals exposed to uranium. Jan 01, 1990

Gallic acid inhibits human lung cancer cell lines in vitro, and amplifies the effect of anti-cancer drugs in lung cancer therapy.Nov 01, 2001

Gallic acid inhibits tumor growth and progression in prostate cancer cells.May 01, 2008

Gallic acid is a potential therapeutic agent for treating cardiac hypertrophy and oxidative stress.Nov 14, 2017

Gallic acid may be used as a therapeutic agent for allergic rhinitis.Mar 14, 2019

Gallic acid may have ameliorative effects on the prepubertal rat testes physiopathology.Aug 12, 2015

Gallic acid might be a potential therapy in treating PCOS.Dec 31, 2021

Gallic acid might be a viable wound healing agent and a potential intervention to treat wounds resulting from metabolic complications.Dec 31, 2015

Gallic acid potentiate the antihyperglycemic effect of acarbose and metformin.Jan 23, 2020

Gallic acid protects against bisphenol A-induced alterations in the cardio-renal system.Oct 31, 2018

Gallic acid protects against high fat diet induced DNA damage.Jul 22, 2018

Gallic acid protects particulate matter (PM10) triggers cardiac oxidative stress and inflammation causing heart adverse events in rats.Apr 29, 2019

Gallic acid protects the liver against NAFLD induced by dust exposure and high-fat diet.Aug 31, 2021

Gallic acid protects the liver in rats against injuries induced by transient ischemia-reperfusion.Mar 31, 2019

Gallic acid reduces neural damage and brain amyloid neuropathology and improves cognitive function.Mar 31, 2016

Gallic acid remarkably ameliorated the destabilization of liver tissue architecture caused by N-nitrosodiethylamine.May 31, 2017

Gallic acid reverses neurochemical changes induced by prolonged ethanol exposure in the zebrafish brain.Dec 03, 2020

Gallic acid suppressed tumorigenesis by an LncRNA MALAT1-Wnt/β-catenin axis in hepatocellular carcinoma.Dec 31, 2020

Gallic acid treatment protects intestinal tissue against ischemia-reperfusion.May 14, 2023

Gallic and ascorbic acids supplementation alleviate cognitive deficits and neuropathological damage exerted by cadmium chloride.Aug 23, 2022

Gallic and hesperidin ameliorate electrolyte imbalances in AlCl3-induced nephrotoxicity.Dec 31, 2021

Neuroprotection by luteolin and gallic acid against cobalt chloride-induced behavioural, morphological and neurochemical alterations in Wistar rats.Dec 31, 2018

Oral gallic acid improve liver steatosis and metabolism modulating hepatic lipogenic markers in obese mice.Feb 17, 2020

Pentaherbs formula can ameliorate allergic inflammation and attenuate the activation of eosinophils.Dec 31, 2015

Pomegranate fruit extract and its components suppressed the formation of AGEs from bovine serum albumin and sugars.Aug 04, 2015

Protective effect of gallic acid on doxorubicin-induced ovarian toxicity.Dec 22, 2022

Protective effect of silymarin and gallic acid against cisplatin-induced nephrotoxicity and hepatotoxicity.Dec 31, 2021

Protective effects of crocin and gallic acid on the liver damage.Dec 31, 2022

Radioprotective role of natural polyphenols: from sources to mechanisms. Apr 17, 2021

The antioxidant gallic acid induces anxiolytic-like effects in streptozotocin-induced diabetes.Jun 22, 2018

The plant phenol known as gallic acid inhibits liver metastasis of mastocytoma, melanoma and lymphoma cells in a mouse experimental model. Nov 01, 2001

These results identify gallic acid as a potential therapeutic agent for the treatment of keloids.Sep 26, 2018

These results indicate that gallic acid exhibits robust antioxidant and antifibrosis effectsDec 31, 2017

These results show that the activation of the hippocampal BDNF-Akt-mTOR signaling is involved in the antidepressant-like effects of gallic acid.Oct 02, 2018

Structure-based drug designing for potential antiviral activity of selected natural products from Ayurveda against SARS-CoV-2 spike glycoprotein and its cellular receptor.May 31, 2020

A review of phenolic compounds as beneficial phytochemicals in pomegranate.Sep 29, 2018

Addition of gallic acid overcomes resistance to cisplatin in ovarian cancer cell lines.Jul 31, 2022

Gallic Acid

View the Evidence:
125 Abstracts with Gallic Acid Research