Gallic Acid

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89 Diseases Researched for Gallic Acid
NameACCKFocus
DNA damage212Locked
Diabetes: Oxidative Stress212Locked
Cadmium Poisoning 110Locked
Diabetes Mellitus: Type 248Locked
Inflammation46Locked
Obesity36Locked
Oxidative Stress46Locked
Diabetic Complications35Locked
Advanced Glycation End products (AGE)24Locked
Anxiety24Locked
Chemotherapy-Induced Toxicity: Cyclophosphamide24Locked
Dyslipidemias24Locked
Insulin Resistance24Locked
Liver Fibrosis24Locked
Lung Cancer34Locked
Uranium Poisoning24Locked
Alcohol Toxicity 23Locked
Bisphenol Toxicity23Locked
Chemically-Induced Liver Damage23Locked
Colon Cancer23Locked
Gastrointestinal Inflammation23Locked
Heart Failure23Locked
Heavy Metal Toxicity23Locked
Liver Cancer23Locked
Melanoma23Locked
Oral Cancer33Locked
Acute Myeloid Leukemia22Locked
Air Pollution Linked Toxicity12Locked
Allergic Rhinitis12Locked
Atopic Dermatitis12Locked
Brain Inflammation 12Locked
Candida Albicans12Locked
Candida Infection 22Locked
Cardiomyopathy12Locked
Cervical Cancer22Locked
Cognitive Decline/Dysfunction12Locked
Colitis12Locked
Dementia: Alzheimer Type12Locked
Depression12Locked
Diabetes: Cognitive Dysfunction12Locked
Endothelial Dysfunction12Locked
Hyperglycemia12Locked
Hypertension12Locked
Influenza12Locked
Influenza A12Locked
Influenza B 12Locked
Keloid12Locked
Kidney Damage: Chemically-Induced12Locked
Lipopolysaccharide-Induced Toxicity12Locked
Liver Injury: Ischemia/reperfusion 12Locked
Liver Steatosis12Locked
Lymphoma12Locked
Mastocytoma12Locked
Memory Disorders12Locked
Myocardial Fibrosis 12Locked
Paraquat Toxicity12Locked
Prostate Cancer12Locked
Wound Healing12Locked
Abortion: Spontaneous11Locked
Acute lymphoblastic leukemia (ALL)11Locked
Alcoholic Liver Disease11Locked
Alzheimer's Disease11Locked
Aspergillosis11Locked
Atherosclerosis11Locked
Bacterial Vaginosis11Locked
Breast Cancer11Locked
Breast Cancer: Triple Negative 11Locked
Carcinoma: Non-Small-Cell Lung11Locked
Cardiovascular Diseases11Locked
Cholangiocarcinoma11Locked
Coronavirus Infection11Locked
Diabetes Mellitus: Type 111Locked
Drug-Induced Toxicity: Gastrointestinal11Locked
Drug-Induced Toxicity: Indomethacin11Locked
Esophageal Cancer11Locked
Fatigue11Locked
Fibrosarcoma11Locked
Gastric Ulcer11Locked
Giardiasis11Locked
HIV Infections11Locked
Helicobacter Pylori Infection11Locked
Human Papillomavirus (HPV)11Locked
Leukemia11Locked
Neurodegenerative Diseases11Locked
Non-Small-Cell Lung Carcinoma11Locked
Rhinovirus Infection 11Locked
Staphylococcus aureus infection11Locked
Stomach Cancer11Locked
Allergies10Locked
62 Pharmacological Actions Researched for Gallic Acid
NameACCKFocus
Antioxidants2246Locked
Anti-Inflammatory Agents1637Locked
Apoptotic1618Locked
Antiproliferative 1114Locked
Neuroprotective Agents712Locked
Interleukin-6 Downregulation611Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor611Locked
Hepatoprotective58Locked
Hypoglycemic Agents48Locked
Anti-Fibrotic47Locked
Cardioprotective46Locked
Renoprotective36Locked
MicroRNA modulator35Locked
Antineoplastic Agents44Locked
Antiviral Agents34Locked
Cell cycle arrest34Locked
Chemopreventive34Locked
Hypolipidemic24Locked
Insulin Sensitizers24Locked
Chemotherapeutic33Locked
Immunomodulatory23Locked
Adiponectin upregulation12Locked
Anti-Anxiety Agents12Locked
Anti-metastatic12Locked
Anticarcinogenic Agents12Locked
Anticholesteremic Agents12Locked
Antidepressive Agents12Locked
Antifungal Agents12Locked
Antihypertensive Agents12Locked
Bcl-2 protein down-regulation22Locked
Brain-derived neurotrophic factor modulator12Locked
Chelating Agents12Locked
Chemoprotective Agents12Locked
Chemosensitizer22Locked
Cyclooxygenase 2 Inhibitors12Locked
Cytoprotective12Locked
Gastroprotective22Locked
Genoprotective12Locked
Immunomodulatory: Th17 downregulation12Locked
Interleukin-1 beta downregulation12Locked
Interleukin-4 downregulation12Locked
Interleukin-5 downregulation12Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor22Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor22Locked
Tumor Suppressor Protein p53 Upregulation22Locked
interleukin-13 down-regulation12Locked
Anti-Bacterial Agents11Locked
Anti-Ulcer Agents11Locked
Antigiardial agents11Locked
Antimicrobial11Locked
Antiparasitic Agents11Locked
Cytotoxic11Locked
Enzyme Activators11Locked
Enzyme Inhibitors11Locked
HIV Protease Inhibitors11Locked
Insulin-releasing11Locked
NF-kappaB Inhibitor11Locked
Nitric Oxide Inhibitor11Locked
Nrf2 activation11Locked
P21 Activation11Locked
Prostaglandin PGE2 downregulation11Locked
Reverse Transcriptase Inhibitors11Locked

View the Evidence:
106 Abstracts with Gallic Acid Research

[+]

Gallic acid improves health associated biochemical parameters and prevents oxidative damage of DNA in type 2 diabetes patients.Nov 27, 2017

Pubmed Data : Mol Nutr Food Res. 2017 Nov 28. Epub 2017 Nov 28. PMID: 29193677
Article Published Date : Nov 27, 2017
Study Type : Human Study
Additional Links
Substances : Gallic Acid
Diseases : Diabetes: Oxidative Stress, DNA damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Glutathione administration with EDTA might be an effective treatment modality for patients with cadmium intoxication.Apr 22, 2010

Pubmed Data : Hum Exp Toxicol. 2010 Apr 22. Epub 2010 Apr 22. PMID: 20413561
Article Published Date : Apr 22, 2010
Study Type : Human Study
Additional Links
Substances : Gallic Acid
Diseases : Cadmium Poisoning
Therapeutic Actions : Chelation Therapy: EDTA
[+]

Gallic and butyric acids modulated NLRP3 inflammasome markers in a co-culture model of intestinal inflammation.Nov 30, 2020

Pubmed Data : Food Chem Toxicol. 2020 Dec ;146:111835. Epub 2020 Oct 29. PMID: 33130239
Article Published Date : Nov 30, 2020
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Gastrointestinal Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Ameliorative effects of gallic acid on cisplatin-induced nephrotoxicity.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2021 ;2021:2195238. Epub 2021 Oct 26. PMID: 34746299
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Chemoprotective Agents, Renoprotective
[+]

Antidiabetic potential of gallic acid from Emblica officinalis.Mar 31, 2019

Pubmed Data : Phytomedicine. 2019 Apr 1:152906. Epub 2019 Apr 1. PMID: 31064680
Article Published Date : Mar 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Gallic Acid, Indian Gooseberry
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anticholesteremic Agents, Antihypertensive Agents, Hypoglycemic Agents, Insulin Sensitizers
[+]

Antifibrotic effects of gallic acid on hepatic stellate cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2019 Jan ;9(1):45-53. Epub 2018 Apr 27. PMID: 30671365
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic
[+]

Antioxidant, anti-inflammatory and protective potential of gallic acid against paraquat-induced liver toxicity in male rats.Oct 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2021 Nov-Dec;11(6):633-644. PMID: 34804900
Article Published Date : Oct 31, 2021
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
Problem Substances : Paraquat
[+]

Black raspberry seed and gallic acid show potent and broad antiviral activity against influenza A and B type viruses.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Viruses. 2016 ;8(6). Epub 2016 Jun 6. PMID: 27275830
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Black Raspberry Seed, Gallic Acid
Diseases : Influenza, Influenza A, Influenza B
Pharmacological Actions : Antiviral Agents
[+]

Co-administration of antioxidant significantly increased plasma level of curcumin in animal models.Nov 25, 2015

Pubmed Data : Mol Nutr Food Res. 2015 Nov 26. Epub 2015 Nov 26. PMID: 26608515
Article Published Date : Nov 25, 2015
Study Type : Animal Study
Additional Links
Substances : Caffeic Acid, Curcumin, Gallic Acid, Rosmarinic acid, Vitamin C
Diseases : Colon Cancer
Pharmacological Actions : Antioxidants, Antiproliferative
Additional Keywords : Increased Bioavailability, Metabolites
[+]

Curcumin and gallic acid have a protective role in advanced glycation end products induces systemic inflammation and weight gain.Feb 08, 2018

Pubmed Data : Food Chem Toxicol. 2018 Feb 9. Epub 2018 Feb 9. PMID: 29432842
Article Published Date : Feb 08, 2018
Study Type : Animal Study
Additional Links
Substances : Curcumin, Gallic Acid
Diseases : Advanced Glycation End products (AGE), Obesity
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Advanced Glycation End products (AGE), Anti-Inflammatory Agents, CURCUMIN, Gallic Acid, obesity
[+]

Curcumin could inhibit the pro-oxidant effects of gallic acid.Dec 26, 2015

Pubmed Data : Ren Fail. 2015 Dec 27:1-9. Epub 2015 Dec 27. PMID: 26707166
Article Published Date : Dec 26, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin, Gallic Acid
Pharmacological Actions : Antioxidants
[+]

Effects of Moringa oleifera leaf extracts and its bioactive compound gallic acid on reducing toxicities of heavy metals.Apr 30, 2021

Pubmed Data : Chemosphere. 2021 May ;270:128659. Epub 2020 Oct 19. PMID: 33757277
Article Published Date : Apr 30, 2021
Study Type : Animal Study
Additional Links
Substances : Gallic Acid, Moringa oleifera
Diseases : Heavy Metal Toxicity
Pharmacological Actions : Antioxidants, Chelating Agents
Additional Keywords : Plant Extracts
Problem Substances : Cadmium, Lead
[+]

Gall of Quercus brantii is able to exert antioxidative and anti-inflammatory effects on the biochemical and pathological parameters of colitis.Dec 21, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Med Sci. 2014 Dec 22 ;10(6):1225-34. PMID: 25624862
Article Published Date : Dec 21, 2014
Study Type : Animal Study
Additional Links
Substances : Gallic Acid, Oak
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Gallic acid ameliorates atopic dermatitis-like skin inflammation through immune regulation.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Cosmet Investig Dermatol. 2021 ;14:1675-1683. Epub 2021 Nov 16. PMID: 34815684
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Atopic Dermatitis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
[+]

Gallic acid ameliorates sodium arsenite-induced renal and hepatic toxicity.Mar 24, 2019

Pubmed Data : Drug Chem Toxicol. 2019 Mar 25:1-12. Epub 2019 Mar 25. PMID: 30907158
Article Published Date : Mar 24, 2019
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Hepatoprotective, Renoprotective
Problem Substances : Arsenite
[+]

Gallic acid and myricetin-rich Labisia pumila extract mitigated multiple diabetic eye disorders in rats.Oct 06, 2021

Pubmed Data : J Food Biochem. 2021 Oct 7:e13948. Epub 2021 Oct 7. PMID: 34622461
Article Published Date : Oct 06, 2021
Study Type : Animal Study
Additional Links
Substances : Gallic Acid, Myricetin
Diseases : Diabetic Complications, Diabetic Retinopathy
Pharmacological Actions : Anti-Inflammatory Agents, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Gallic acid and p-coumaric acid attenuate type 2 diabetes-induced neurodegeneration.Dec 31, 2016

Pubmed Data : Metab Brain Dis. 2017 08 ;32(4):1279-1286. Epub 2017 Jun 2. PMID: 28573601
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Gallic Acid, P-Coumaric Acid
Diseases : Diabetes: Cognitive Dysfunction, Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Gallic acid and p-coumaric acid exhibited marked anti-diabetic action.Aug 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Sep ;105:1091-1097. Epub 2018 Jun 20. PMID: 30021345
Article Published Date : Aug 31, 2018
Study Type : Animal Study
Additional Links
Substances : Gallic Acid, P-Coumaric Acid
Diseases : Diabetes Mellitus: Type 2, Dyslipidemias
Pharmacological Actions : Adiponectin upregulation, Anti-Inflammatory Agents, Hypolipidemic, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Gallic acid attenuated lipopolysaccharide-induced neuroinflammation.Dec 11, 2019

Pubmed Data : Mol Neurobiol. 2019 Dec 12. Epub 2019 Dec 12. PMID: 31832973
Article Published Date : Dec 11, 2019
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Gallic acid attenuates high-fat diet fed-streptozotocin-induced insulin resistance.Dec 14, 2014

Pubmed Data : Eur J Pharmacol. 2014 Dec 15 ;745:201-16. Epub 2014 Nov 5. PMID: 25445038
Article Published Date : Dec 14, 2014
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Hypoglycemic Agents, Insulin Sensitizers
[+]

Gallic acid can modify the reproductive toxicity of cyclophosphamide.Mar 17, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Urol J. 2019 Mar 18. Epub 2019 Mar 18. PMID: 30882156
Article Published Date : Mar 17, 2019
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions : Antioxidants
[+]

Gallic acid could alleviate the noxious effects of paraquat on the antioxidant defense system and renal tissue.Jul 29, 2020

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2020 Jul 30. Epub 2020 Jul 30. PMID: 32734364
Article Published Date : Jul 29, 2020
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Kidney Damage: Chemically-Induced, Paraquat Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Renoprotective
Problem Substances : Paraquat
[+]

Gallic acid could be used for improving metabolic disorders such as insulin resistance and dyslipidemia.Oct 23, 2019

Pubmed Data : Nutr Res. 2019 Oct 24 ;73:58-66. Epub 2019 Oct 24. PMID: 31841748
Article Published Date : Oct 23, 2019
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Dyslipidemias, Inflammation, Insulin Resistance, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-6 Downregulation
[+]

Gallic acid enhances detoxification in the chelation of uranium in mice. Mar 01, 1989

Pubmed Data : Pharmacol Toxicol. 1989 Mar;64(3):247-51. PMID: 2726688
Article Published Date : Mar 01, 1989
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Uranium Poisoning
[+]

Gallic acid exerted protective effects against stress-induced mood and memory deficit disorders.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2018 Dec ;21(12):1232-1237. PMID: 30627366
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Anxiety, Memory Disorders
Pharmacological Actions : Neuroprotective Agents
[+]

Gallic acid has the capacity to protect against reproductive toxicity induced by cyclophosphamide.Jul 28, 2015

Pubmed Data : Andrologia. 2015 Jul 29. Epub 2015 Jul 29. PMID: 26223283
Article Published Date : Jul 28, 2015
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide, Oxidative Stress
Pharmacological Actions : Antioxidants, Chemoprotective Agents
[+]

Gallic acid has the potential to be developed further as a natural antifungal agent for clinical use.May 18, 2017

Pubmed Data : Phytother Res. 2017 May 19. Epub 2017 May 19. PMID: 28524381
Article Published Date : May 18, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Candida Albicans
Pharmacological Actions : Antifungal Agents
[+]

Gallic acid has therapeutic potential for the treatment of heart failure-induced pulmonary fibrosis.Nov 30, 2017

Pubmed Data : Vascul Pharmacol. 2017 Dec ;99:74-82. Epub 2017 Oct 31. PMID: 29097327
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Heart Failure, Myocardial Fibrosis
Pharmacological Actions : Anti-Fibrotic
[+]

Gallic acid improves inflammation, oxidative stress and hypotension result from diabetes.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Endocrinol (Buchar). 2019 Apr-Jun;15(2):187-194. PMID: 31508175
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Cardiomyopathy, Diabetes: Oxidative Stress, Diabetic Complications, Endothelial Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hypolipidemic, Interleukin-6 Downregulation, MicroRNA modulator, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Gallic acid improves uranium detoxification in animals exposed to uranium. Jan 01, 1990

Pubmed Data : Fundam Appl Toxicol. 1990 Jan;14(1):88-95. PMID: 2307325
Article Published Date : Jan 01, 1990
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Uranium Poisoning
Therapeutic Actions : Chelation Therapy: EDTA
[+]

Gallic acid inhibits human lung cancer cell lines in vitro, and amplifies the effect of anti-cancer drugs in lung cancer therapy.Nov 01, 2001

Pubmed Data : Anticancer Drugs. 2001 Nov;12(10):847-52. PMID: 11707653
Article Published Date : Nov 01, 2001
Study Type : Transgenic Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Lung Cancer
[+]

Gallic acid inhibits tumor growth and progression in prostate cancer cells.May 01, 2008

Pubmed Data : Mol Cancer Ther. 2008 May;7(5):1258-67. Epub 2008 Apr 29. PMID:18445658
Article Published Date : May 01, 2008
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Prostate Cancer
[+]

Gallic acid is a potential therapeutic agent for treating cardiac hypertrophy and oxidative stress.Nov 14, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Nov 15 ;7(1):15607. Epub 2017 Nov 15. PMID: 29142252
Article Published Date : Nov 14, 2017
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Hypertension
Pharmacological Actions : Antioxidants
[+]

Gallic acid may be used as a therapeutic agent for allergic rhinitis.Mar 14, 2019

Pubmed Data : Int Immunopharmacol. 2019 Mar 15 ;70:512-519. Epub 2019 Mar 15. PMID: 30884431
Article Published Date : Mar 14, 2019
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Allergic Rhinitis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, interleukin-13 down-regulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

Gallic acid may have ameliorative effects on the prepubertal rat testes physiopathology.Aug 12, 2015

Pubmed Data : Environ Toxicol. 2015 Aug 13. Epub 2015 Aug 13. PMID: 26268881
Article Published Date : Aug 12, 2015
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Oxidative Stress
Pharmacological Actions : Cytoprotective
Anti Therapeutic Actions : Wi-Fi Radiation
[+]

Gallic acid might be a viable wound healing agent and a potential intervention to treat wounds resulting from metabolic complications.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2016 ;21(7). Epub 2016 Jul 8. PMID: 27399667
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Wound Healing
Pharmacological Actions : Antioxidants
[+]

Gallic acid potentiate the antihyperglycemic effect of acarbose and metformin.Jan 23, 2020

Pubmed Data : Arch Physiol Biochem. 2020 Jan 24:1-9. Epub 2020 Jan 24. PMID: 31979987
Article Published Date : Jan 23, 2020
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Natural Substance/Drug Synergy
[+]

Gallic acid protects against bisphenol A-induced alterations in the cardio-renal system.Oct 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Nov ;107:1786-1794. Epub 2018 Sep 13. PMID: 30257398
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Bisphenol Toxicity
Pharmacological Actions : Cardioprotective, Renoprotective
Problem Substances : Bisphenol A
[+]

Gallic acid protects against high fat diet induced DNA damage.Jul 22, 2018

Pubmed Data : Eur J Nutr. 2018 Jul 23. Epub 2018 Jul 23. PMID: 30039436
Article Published Date : Jul 22, 2018
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : DNA damage, Obesity
Pharmacological Actions : Genoprotective, Hypoglycemic Agents
[+]

Gallic acid protects particulate matter (PM10) triggers cardiac oxidative stress and inflammation causing heart adverse events in rats.Apr 29, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 Apr 30. Epub 2019 Apr 30. PMID: 31041709
Article Published Date : Apr 29, 2019
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Air Pollution Linked Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Gallic acid protects the liver against NAFLD induced by dust exposure and high-fat diet.Aug 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2021 Sep-Oct;11(5):527-540. PMID: 34745924
Article Published Date : Aug 31, 2021
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Inflammation, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Gallic acid protects the liver in rats against injuries induced by transient ischemia-reperfusion.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2019 Apr ;22(4):439-444. PMID: 31168350
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Liver Injury: Ischemia/reperfusion
Pharmacological Actions : Hepatoprotective, MicroRNA modulator
[+]

Gallic acid reduces neural damage and brain amyloid neuropathology and improves cognitive function.Mar 31, 2016

Pubmed Data : Basic Clin Neurosci. 2016 Apr ;7(2):97-106. PMID: 27303604
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Dementia: Alzheimer Type
Pharmacological Actions : Neuroprotective Agents
[+]

Gallic acid remarkably ameliorated the destabilization of liver tissue architecture caused by N-nitrosodiethylamine.May 31, 2017

Pubmed Data : Tumour Biol. 2017 Jun ;39(6):1010428317699127. PMID: 28618930
Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Liver Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antioxidants, Apoptotic, Chemopreventive
Additional Keywords : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antioxidants, Apoptotic, Chemopreventive, Gallic Acid, liver cancer
Problem Substances : N-nitrosodiethylamine
[+]

Gallic acid reverses neurochemical changes induced by prolonged ethanol exposure in the zebrafish brain.Dec 03, 2020

Pubmed Data : Neuroscience. 2020 Dec 4. Epub 2020 Dec 4. PMID: 33285238
Article Published Date : Dec 03, 2020
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Alcohol Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Gallic acid suppressed tumorigenesis by an LncRNA MALAT1-Wnt/β-catenin axis in hepatocellular carcinoma.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:708967. Epub 2021 Oct 6. PMID: 34690755
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Liver Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Wnt/β-catenin signaling pathway modulation
[+]

Neuroprotection by luteolin and gallic acid against cobalt chloride-induced behavioural, morphological and neurochemical alterations in Wistar rats.Dec 31, 2018

Pubmed Data : Neurotoxicology. 2019 09 ;74:252-263. Epub 2019 Jul 27. PMID: 31362009
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Gallic Acid, Luteolin
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Cobalt
[+]

Oral gallic acid improve liver steatosis and metabolism modulating hepatic lipogenic markers in obese mice.Feb 17, 2020

Pubmed Data : Exp Gerontol. 2020 Feb 18:110881. Epub 2020 Feb 18. PMID: 32084535
Article Published Date : Feb 17, 2020
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Liver Steatosis
Pharmacological Actions : Hepatoprotective
[+]

Pentaherbs formula can ameliorate allergic inflammation and attenuate the activation of eosinophils.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2016 ;21(4). Epub 2016 Apr 20. PMID: 27104513
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Berberine, Chlorogenic Acid, Gallic Acid
Diseases : Atopic Dermatitis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation
[+]

Pomegranate fruit extract and its components suppressed the formation of AGEs from bovine serum albumin and sugars.Aug 04, 2015

Pubmed Data : J Agric Food Chem. 2015 Aug 5. Epub 2015 Aug 5. PMID: 26242637
Article Published Date : Aug 04, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ellagic Acid, Gallic Acid, Pomegranate
Diseases : Advanced Glycation End products (AGE)
Additional Keywords : Plant Extracts
[+]

Protective effect of silymarin and gallic acid against cisplatin-induced nephrotoxicity and hepatotoxicity.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Pract. 2022 ;2022:6541026. Epub 2022 Apr 16. PMID: 35685593
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Gallic Acid, Silymarin
Diseases : Chemotherapy-Induced Kidney Damage, Chemotherapy-Induced Toxicity: Cisplatin, Liver Damage: Drug-Induced, Oxidative Stress
Pharmacological Actions : Chemoprotective Agents, Hepatoprotective, Renoprotective
[+]

Radioprotective role of natural polyphenols: from sources to mechanisms. Apr 17, 2021

Pubmed Data : Anticancer Agents Med Chem. 2021 Apr 18. Epub 2021 Apr 18. PMID: 33874875
Article Published Date : Apr 17, 2021
Study Type : Animal Study
Additional Links
Substances : Apigenin, Caffeic acid phenethyl ester, Curcumin, EGCG (Epigallocatechin gallate), Epicatechin, Gallic Acid, Polyphenols, Quercetin, Resveratrol, Rutin, Silibinin
Diseases : Radiation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Radioprotective
[+]

The antioxidant gallic acid induces anxiolytic-like effects in streptozotocin-induced diabetes.Jun 22, 2018

Pubmed Data : Metab Brain Dis. 2018 Jun 23. Epub 2018 Jun 23. PMID: 29934859
Article Published Date : Jun 22, 2018
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Anxiety, Diabetic Complications
Pharmacological Actions : Anti-Anxiety Agents, Antioxidants
[+]

The plant phenol known as gallic acid inhibits liver metastasis of mastocytoma, melanoma and lymphoma cells in a mouse experimental model. Nov 01, 2001

Pubmed Data : Anticancer Res. 2001 Nov-Dec;21(6A):3875-80. PMID: 11911262
Article Published Date : Nov 01, 2001
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Lymphoma, Mastocytoma, Melanoma
Pharmacological Actions : Anti-metastatic
[+]

These results identify gallic acid as a potential therapeutic agent for the treatment of keloids.Sep 26, 2018

Pubmed Data : Acta Biochim Biophys Sin (Shanghai). 2018 Sep 27. Epub 2018 Sep 27. PMID: 30265275
Article Published Date : Sep 26, 2018
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Keloid
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

These results indicate that gallic acid exhibits robust antioxidant and antifibrosis effectsDec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2018 ;2018:1682743. Epub 2018 Dec 2. PMID: 30627538
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic
[+]

These results show that the activation of the hippocampal BDNF-Akt-mTOR signaling is involved in the antidepressant-like effects of gallic acid.Oct 02, 2018

Pubmed Data : Metab Brain Dis. 2018 Oct 3. Epub 2018 Oct 3. PMID: 30280285
Article Published Date : Oct 02, 2018
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Depression
Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator
[+]

Structure-based drug designing for potential antiviral activity of selected natural products from Ayurveda against SARS-CoV-2 spike glycoprotein and its cellular receptor.May 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Virusdisease. 2020 Jun ;31(2):179-193. Epub 2020 May 24. PMID: 32656311
Article Published Date : May 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Gallic Acid, Luteolin, Mangiferin, Naringenin , Piperine, Quercetin, Resveratrol
Diseases : Coronavirus Infection
Pharmacological Actions : Antiviral Agents
[+]

A review of phenolic compounds as beneficial phytochemicals in pomegranate.Sep 29, 2018

Pubmed Data : Food Chem. 2018 Sep 30 ;261:75-86. Epub 2018 Apr 13. PMID: 29739608
Article Published Date : Sep 29, 2018
Study Type : Review
Additional Links
Substances : Anthocyanins, Cinnamic acid, Cyanidin, Delphinidin, Ellagic Acid, Flavonoids, Gallic Acid, Pomegranate, Punicalagin
[+]

Anti-Helicobacter pylori and antiulcerogenic activities of the root cortex of Paeonia suffruticosa.Dec 31, 2012

Pubmed Data : Biol Pharm Bull. 2013 ;36(10):1535-9. PMID: 24088252
Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Catechin , Gallic Acid, Peony
Diseases : Alcohol Toxicity , Gastric Ulcer, Helicobacter Pylori Infection
Pharmacological Actions : Anti-Ulcer Agents, Antioxidants
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Anti-inflammatory effects of gallic acid in human gestational tissues in vitro.Jan 09, 2020

Pubmed Data : Reproduction. 2020 10 ;160(4):561-578. PMID: 32698152
Article Published Date : Jan 09, 2020
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Abortion: Spontaneous, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Antimicrobial and enhancement of the antibiotic activity by phenolic compounds.Sep 30, 2016

Pubmed Data : Microb Pathog. 2016 Oct ;99:56-61. Epub 2016 Aug 3. PMID: 27497894
Article Published Date : Sep 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Caffeic Acid, Gallic Acid, Pyrogallol
Diseases : Candida Infection , Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Natural Substance/Drug Synergy
[+]

Antitumour effects of gallic acid and ellagic acid, on sensitive and multidrug-resistant leukaemia HL60 cells.Mar 04, 2019

Pubmed Data : Phytother Res. 2019 Mar 5. Epub 2019 Mar 5. PMID: 30838722
Article Published Date : Mar 04, 2019
Study Type : In Vitro Study
Additional Links
Substances : Ellagic Acid, Gallic Acid
Diseases : Acute Myeloid Leukemia
Pharmacological Actions : Apoptotic
[+]

Cytotoxic activity of caffeic acid and gallic acid against MCF-7 human breast cancer cells.Oct 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2019 Nov-Dec;9(6):574-586. PMID: 31763216
Article Published Date : Oct 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Caffeic Acid, Gallic Acid
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, P21 Activation, Tumor Suppressor Protein p53 Upregulation
[+]

Dietary gallic acid and anthocyanin cytotoxicity on human fibrosarcoma HT1080 cells.Jan 31, 2014

Pubmed Data : Food Funct. 2014 Feb ;5(2):381-9. PMID: 24413695
Article Published Date : Jan 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Anthocyanins, Gallic Acid
Diseases : Fibrosarcoma
Pharmacological Actions : Antineoplastic Agents, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Effect of Gallic acid in potentiating chemotherapeutic effect of paclitaxel in HeLa cervical cancer cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Cell Int. 2019 ;19:154. Epub 2019 Jun 3. PMID: 31171918
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Cervical Cancer
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Ellagic acid, gallic acid and punicalagin may be the compounds responsible for the anti-inflammatory potential of P. granatum.Jan 13, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Jan 14 ;17(1):47. Epub 2017 Jan 14. PMID: 28088220
Article Published Date : Jan 13, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ellagic Acid, Gallic Acid, Pomegranate, Punicalagin
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation
[+]

Fermented oolong tea high in gallic acid as an effective dietary intervention strategy for tobacco-associated cancers.Jan 01, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2018 Jan 2 ;9(1):361-374. Epub 2017 Dec 7. PMID: 29416619
Article Published Date : Jan 01, 2018
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Gallic Acid, Oolong tea
Diseases : Lung Cancer, Oral Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : DNA Methylation, Epigenetic Modification In Cancer
[+]

Gallic acid and aqueous S. cumini leaf extract exhibited immunomodulatory properties.Sep 11, 2015

Pubmed Data : Drug Chem Toxicol. 2015 Sep 12:1-8. Epub 2015 Sep 12. PMID: 26364973
Article Published Date : Sep 11, 2015
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid, Jambul
Diseases : Oxidative Stress
Pharmacological Actions : Immunomodulatory
Additional Keywords : Plant Extracts
[+]

Gallic acid appears to break down neoplastic phenotype of oral squamous cell carcinoma cells by interfering with leptin pathway.Dec 09, 2017

Pubmed Data : Pathol Res Pract. 2017 Dec 10. Epub 2017 Dec 10. PMID: 29254802
Article Published Date : Dec 09, 2017
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Oral Cancer
Pharmacological Actions : Chemotherapeutic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Gallic acid can induce apoptosis in EGFR-dependent lung cancers that are dependent on EGFR for growth and survival.Sep 30, 2016

Pubmed Data : Bioorg Med Chem Lett. 2016 Oct 1 ;26(19):4571-5. Epub 2016 Aug 27. PMID: 27597244
Article Published Date : Sep 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Gallic acid could be a potential candidate for the development of anti-HPV agents.Jun 08, 2015

Pubmed Data : J Med Virol. 2015 Jun 9. Epub 2015 Jun 9. PMID: 26059022
Article Published Date : Jun 08, 2015
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Cervical Cancer, Human Papillomavirus (HPV)
Pharmacological Actions : Antiproliferative , Apoptotic, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Selective Cytotoxicity
[+]

Gallic acid extracted from the leaves of Phyllanthus emblica exhibits anti-cancer activity against liver cancer. Feb 01, 2011

Pubmed Data : Zhong Yao Cai. 2011 Feb ;34(2):246-9. PMID: 21823485
Article Published Date : Feb 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid, Phyllanthus emblica
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Cell cycle arrest, Chemopreventive
[+]

Gallic acid for cancer therapy: Molecular mechanisms and boosting efficacy by nanoscopical delivery.Sep 24, 2021

Pubmed Data : Food Chem Toxicol. 2021 Sep 25 ;157:112576. Epub 2021 Sep 25. PMID: 34571052
Article Published Date : Sep 24, 2021
Study Type : Review
Additional Links
Substances : Gallic Acid
Diseases : Cancers: All
Pharmacological Actions : Antiproliferative , Apoptotic, Chemotherapeutic
[+]

Gallic acid from Terminalia chebula inhibited the growth of esophageal carcinoma cells.Oct 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2020 Nov ;23(11):1401-1408. PMID: 33235697
Article Published Date : Oct 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid, Terminalia chebula
Diseases : Esophageal Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation
[+]

Gallic acid has anticancer activity and enhances the anticancer effects of cisplatin in non‑small cell lung cancer A549 cells.Feb 28, 2019

Pubmed Data : Oncol Rep. 2019 Mar ;41(3):1779-1788. Epub 2019 Jan 22. PMID: 30747218
Article Published Date : Feb 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Non-Small-Cell Lung Carcinoma
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

Gallic acid in combination with curcumin could be a possible candidate for chemoprevention agent of triple negative breast cancer.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Bioimpacts. 2018 ;8(3):185-194. Epub 2018 Mar 5. PMID: 30211078
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Gallic Acid
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Apoptotic, Chemopreventive
[+]

Gallic acid induces programmed cell death in human stomach and colon cancer cell lines. Nov 01, 2000

Pubmed Data : Oncol Rep. 2000 Nov-Dec;7(6):1221-3. PMID: 11032918
Article Published Date : Nov 01, 2000
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Colon Cancer, Stomach Cancer
Pharmacological Actions : Apoptotic
[+]

Gallic acid induces programmed cell death in melanoma cells. Oct 07, 2009

Pubmed Data : Chem Biol Interact. 2009 Oct 7;181(2):175-84. Epub 2009 Jul 3. PMID: 19577552
Article Published Date : Oct 07, 2009
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Melanoma
Pharmacological Actions : Apoptotic, NF-kappaB Inhibitor
[+]

Gallic acid inhibits aflatoxin formation in Aspergillus flavus.Jul 02, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxins (Basel). 2018 Jul 3 ;10(7). Epub 2018 Jul 3. PMID: 29970790
Article Published Date : Jul 02, 2018
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Aspergillosis
Pharmacological Actions : Antioxidants
Problem Substances : Aflatoxin
[+]

Gallic acid is effective in the inhibition of proliferation and induction of apoptosis in Jurkat cell line.Oct 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Med Sci. 2016 Nov ;41(6):525-530. PMID: 27853333
Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Acute lymphoblastic leukemia (ALL)
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Gallic acid posesses anti-human rhinovirus activity.Sep 15, 2008

Pubmed Data : Biol Psychiatry. 2008 Sep 15;64(6):468-75. Epub 2008 Jun 5. PMID: 20104501
Article Published Date : Sep 15, 2008
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Rhinovirus Infection
Pharmacological Actions : Antiviral Agents
[+]

Gallic acid preserves beta cell function and exhibits insulin-secreting action. Jul 16, 2009

Pubmed Data : Phytother Res. 2009 Jul 16. PMID: 19610036
Article Published Date : Jul 16, 2009
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Insulin-releasing
Additional Keywords : Beta Cell Regeneration
[+]

Gallic acid prevents 1, 2-Dimethylhydrazine induced colon inflammation, toxicity, mucin depletion, and goblet cell disintegration.Jan 10, 2020

Pubmed Data : Environ Toxicol. 2020 Jan 11. Epub 2020 Jan 11. PMID: 31925992
Article Published Date : Jan 10, 2020
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Gastrointestinal Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective
[+]

Gallic acid protects against ethanol-induced hepatocyte necroptosis via an NRF2-dependent mechanism.Mar 06, 2019

Pubmed Data : Toxicol In Vitro. 2019 Mar 7. Epub 2019 Mar 7. PMID: 30853489
Article Published Date : Mar 06, 2019
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Alcoholic Liver Disease
Pharmacological Actions : Antioxidants, Hepatoprotective, Nrf2 activation
[+]

Gallic acid protects rat liver mitochondria ex vivo from bisphenol A induced oxidative stress mediated damages.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Rep. 2019 ;6:578-589. Epub 2019 Jun 17. PMID: 31293903
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Bisphenol Toxicity, Chemically-Induced Liver Damage, Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective
Problem Substances : Bisphenol A
[+]

Gallic acid targets acute myeloid leukemia via Akt/mTOR-dependent mitochondrial respiration inhibition.Aug 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Sep ;105:491-497. Epub 2018 Jun 5. PMID: 29883944
Article Published Date : Aug 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Acute Myeloid Leukemia
Pharmacological Actions : Antiproliferative , Apoptotic, Chemotherapeutic
[+]

Gallic acid: a dietary polyphenol that exhibits anti-neoplastic activities by modulating multiple oncogenic targets.Nov 17, 2021

Pubmed Data : Anticancer Agents Med Chem. 2021 Nov 18. Epub 2021 Nov 18. PMID: 34802408
Article Published Date : Nov 17, 2021
Study Type : Review
Additional Links
Substances : Gallic Acid
Diseases : Cancers: All
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Gallic acid: A potential anti-cancer agent. Nov 09, 2021

Pubmed Data : Chin J Integr Med. 2021 Nov 10. Epub 2021 Nov 10. PMID: 34755289
Article Published Date : Nov 09, 2021
Study Type : Review
Additional Links
Substances : Gallic Acid
Diseases : Cancers: All, Colon Cancer, Lung Cancer, Prostate Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Apoptotic, cancer cell apoptosis
[+]

Gold nanoparticles enhance the anticancer activity of gallic acid against cholangiocarcinoma cell lines.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(16):7143-7. PMID: 26514503
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid, Gold (nanoparticles)
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antineoplastic Agents, Antiproliferative
[+]

Hypersensitivity of BRCA2 deficient cells to rosemary extract explained by weak PARP inhibitory activity.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Dec 1 ;7(1):16704. Epub 2017 Dec 1. PMID: 29196727
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carnosic Acid, Gallic Acid, Rosemary
Diseases : Lung Cancer
Pharmacological Actions : Cytotoxic
Additional Keywords : BRCA Gene, Plant Extracts
[+]

Molecular mechanisms underlying gallic acid effects against cardiovascular diseases: An update reviewDec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2020 Jan-Feb;10(1):11-23. PMID: 31921604
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Substances : Gallic Acid
Diseases : Cardiovascular Diseases
Pharmacological Actions : Cardioprotective
[+]

Natural compounds attenuate heavy metal-induced PC12 cell damage. May 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Int Med Res. 2020 Jun ;48(6):300060520930847. PMID: 32552232
Article Published Date : May 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Caffeine, Gallic Acid, Resveratrol, Vitamin C, Vitamin E: alpha tocopherol
Diseases : Heavy Metal Toxicity, Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Natural polyphenols prevent indomethacin-induced and diclofenac-induced Caco-2 cell death.Jan 09, 2020

Pubmed Data : J Pharm Pharmacol. 2020 Jan 10. Epub 2020 Jan 10. PMID: 31922618
Article Published Date : Jan 09, 2020
Study Type : In Vitro Study
Additional Links
Substances : Caffeic Acid, Curcumin, EGCG (Epigallocatechin gallate), Gallic Acid, Naringenin , Piperine, Polyphenols, Quercetin, Rutin, Silymarin
Diseases : Drug-Induced Toxicity: Gastrointestinal, Drug-Induced Toxicity: Indomethacin
Pharmacological Actions : Antioxidants, Gastroprotective
Problem Substances : Diclofenac, Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Nelumbo nucifera leaf polyphenol extract and gallic acid inhibit TNF-α-induced vascular smooth muscle cell proliferation and migration.Oct 20, 2020

Pubmed Data : Food Funct. 2020 Oct 21 ;11(10):8602-8611. PMID: 33084700
Article Published Date : Oct 20, 2020
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid, Lotus , Polyphenols
Diseases : Atherosclerosis
Pharmacological Actions : MicroRNA modulator
[+]

Oolong tea accumulates the flavonols myricetin, quercetin, and kaempferol, and high levels of gallic acid. Sep 10, 2008

Pubmed Data : J Agric Food Chem. 2008 Sep 10;56(17):7950-6. Epub 2008 Aug 16. PMID: 18707114
Article Published Date : Sep 10, 2008
Study Type : In Vitro Study
Additional Links
Substances : Catechin , Flavonoids, Gallic Acid, Quercetin
[+]

P. sidoides has cancer cell type-specific anti-proliferative effects and may be a source of novel anticancer molecules.Aug 31, 2016

Pubmed Data : Pharm Biol. 2016 Sep ;54(9):1831-40. Epub 2016 Jan 21. PMID: 26794080
Article Published Date : Aug 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid, Pelargonium sidoides
Diseases : Leukemia
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs
[+]

Polyphenol-rich extracts from strawberry, arctic bramble, blackberry, and cloudberry applied to trophozoites of Giardia duodenalis were as effective as metronidazole in causing trophozoite mortality in vitro. Aug 01, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Parasitology. 2011 Aug ;138(9):1110-6. PMID: 21813029
Article Published Date : Aug 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Blackberry, Cloudberry, Flavonoids, Gallic Acid, Polyphenols, Raspberry, Strawberry, Tannic Acid
Diseases : Giardiasis
Pharmacological Actions : Antigiardial agents, Antiparasitic Agents
Additional Keywords : Antiparasitic Agents, Drug: Metronidazole, Natural Substances Versus Drugs, Plant Extracts
[+]

Polyphenols as inhibitors of antibiotic resistant bacteria-mechanisms underlying rutin interference with bacterial virulence.Mar 20, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2022 Mar 21 ;15(3). Epub 2022 Mar 21. PMID: 35337182
Article Published Date : Mar 20, 2022
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid, Citrus naringin, Ferulic acid, Gallic Acid, Hesperidin, Naringenin , P-Coumaric Acid, Rutin
Diseases : Pseudomonas aeruginosa
Pharmacological Actions : Anti-Bacterial Agents
[+]

Rutin and gallic acid regulates mitochondrial functions via the SIRT1 pathway in C2C12 myotubes.Feb 12, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2021 Feb 13 ;10(2). Epub 2021 Feb 13. PMID: 33668647
Article Published Date : Feb 12, 2021
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid, Rutin
Diseases : Fatigue
Pharmacological Actions : Enzyme Activators
[+]

Studies also show that catechins may prevent the formation of amyloid-β plaques and enhance cognitive functions.May 29, 2017

Pubmed Data : J Alzheimers Dis. 2017 May 30. Epub 2017 May 30. PMID: 28582855
Article Published Date : May 29, 2017
Study Type : Review
Additional Links
Substances : Anthocyanins, Caffeine, Catechin , EGCG (Epigallocatechin gallate), Flavonoids, Gallic Acid, Polyphenols, Theophylline
Diseases : Alzheimer's Disease, Diabetic Complications
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Alzheimer's disease, Anthocyanins, Antioxidants, caffeine, Catechin, Diabetic Complications, EGCG (Epigallocatechin gallate), Flavonoids, Gallic Acid, Neuroprotective Agents, POLYPHENOLS, Theophylline
[+]

Synergistic inactivation of Escherichia coli O157:H7 and Staphylococcus aureus by gallic acid and thymol and its potential application on fresh-cut tomatoes.Mar 31, 2022

Pubmed Data : Food Microbiol. 2022 Apr ;102:103925. Epub 2021 Oct 19. PMID: 34809951
Article Published Date : Mar 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid, Thymol
Diseases : Escherichia coli Infections, Foodborne Pathogens: Prevention/Food Preservation, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Natural Substance Synergy
[+]

The present study shows a novel anti-HIV activity of banaba.Feb 28, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Med Res. 2013 Mar ;137(3):540-8. PMID: 23640562
Article Published Date : Feb 28, 2013
Study Type : In Vitro Study
Additional Links
Substances : Banaba, Ellagic Acid, Gallic Acid
Diseases : HIV Infections
Pharmacological Actions : Enzyme Inhibitors, HIV Protease Inhibitors, Reverse Transcriptase Inhibitors
Additional Keywords : Dose Response, Plant Extracts
[+]

These results suggest that gallic acid is a therapeutic agent for cardiac dysfunction and fibrosis in chronic heart failure.Jun 17, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2018 Jun 18 ;8(1):9302. Epub 2018 Jun 18. PMID: 29915390
Article Published Date : Jun 17, 2018
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Heart Failure
Pharmacological Actions : Anti-Fibrotic, Cardioprotective
[+]

Utilizing liposomal quercetin and gallic acid in localized treatment of vaginal candida infections.Dec 19, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2019 Dec 20 ;12(1). Epub 2019 Dec 20. PMID: 31861805
Article Published Date : Dec 19, 2019
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid, Quercetin
Diseases : Bacterial Vaginosis, Candida Infection
Pharmacological Actions : Antimicrobial
[+]

Gallic acid inhibits mast cell-derived inflammatory allergic reactions.Jan 01, 2004

Pubmed Data : Zhong Xi Yi Jie He Xue Bao. 2004 Jan;2(1):30-2. PMID: 16322071
Article Published Date : Jan 01, 2004
Additional Links
Substances : Gallic Acid
Diseases : Allergies

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Coconut Oil Protects Against Macular Degeneration
Written by GMI Reporter
If you’re experiencing deteriorating vision as you age and don’t want to believe that it’s an unavoidable reality, the results of a recent study on macular degeneration will give you good reasons to get wide-eyed: coconut oil can now add “retina protection” to its long list of health benefits

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