Garlic

Name	AC	CK
Inflammation	17	97
Oxidative Stress	33	74
Hypertension	12	72
C-Reactive Protein	3	60
Diabetes Mellitus: Type 2	6	55
Gastric Cancer	11	54
Helicobacter Pylori Infection	6	53
Obesity	14	51
Cardiovascular Diseases	12	43
Cancers: All	12	41
Breast Cancer	14	36
Colorectal Cancer	7	36
Hyperlipidemia	5	35
Atherosclerosis	5	33
Arterial Calcification	5	32
Blood Pressure: High	2	30
Hypercholesterolemia	7	30
Arteriosclerosis	7	28
Triglycerides: Elevated	4	25
Dyslipidemias	3	24
Ear Infection	3	22
Endothelial Dysfunction	6	22
Lead Poisoning	8	22
Arterial Plaque	3	21
Hepatopulmonary Syndrome	3	21
Blood Diseases	1	20
Coronary Artery Disease	2	20
Hypoglycemia	1	20
Metabolic Diseases	1	20
Nonalcoholic fatty liver disease (NAFLD)	2	20
Osteoarthritis: Knee	2	20
Colon Cancer	8	19
Liver Cancer	6	18
Myocardial Infarction	5	18
Insulin Resistance	4	16
Cytomegalovirus Infections	5	15
Lung Cancer	5	15
DNA damage	8	14
High Fat Diet	7	14
Bacterial Vaginosis	2	13
Staphylococcus aureus infection	10	13
Cadmium Poisoning	6	12
Chemotherapy-Induced Toxicity: Cisplatin	6	12
Diabetic Nephropathy	5	12
Endometrial Cancer	2	12
Liver Disease	2	12
Metabolic Syndrome X	2	12
Streptococcus infections: Group B	2	12
Chemically-Induced Liver Damage	6	11
Chemotherapy-Induced Toxicity: Doxorubicin	5	11
Escherichia coli Infections	10	11
Gingivitis	2	11
Hypoxia	2	11
Leukemia: Monocytic	2	11
Tuberculosis	2	11
Aging	1	10
All-Cause Mortality	1	10
Alopecia	1	10
Arterial Hardening: Elasticity	1	10
Diabetes Mellitus: Type 1	5	10
Diabetes: Lipids/Cholesterol	1	10
Dyspnea	1	10
Fibrinogen: Elevated	1	10
Hair Loss	1	10
Heart Attack	1	10
High Homocysteine	1	10
Hyperhomocysteinemia	1	10
Iatrogenic Disease	1	10
Intermittent Claudication	1	10
Intima Media Thickening	1	10
Lipid Peroxidation	6	10
Low Immune Function: Natural Killer Cells	1	10
Lung Cancer: Prevention	1	10
Multiple Myeloma: Prevention	1	10
Otitis media	1	10
Pancreatic Cancer	1	10
Peripheral Vascular Diseases	1	10
Prostate Cancer	1	10
Rheumatoid Arthritis	1	10
Stroke: Prevention	1	10
Thrush	1	10
Vulvovaginitis: Infectious	1	10
Bacterial Infections: Resistance/Biofilm Formation	7	8
Diabetic Complications	4	8
Gallstones	5	8
High Cholesterol	4	8
Pseudomonas aeruginosa	7	8
Schistosomiasis	3	8
Wound Healing	4	8
Coronavirus Infection	7	7
Lipopolysaccharide-Induced Toxicity	4	7
Nicotine/Tobacco Toxicity	4	7
Alcoholic Liver Disease	4	6
Depression	3	6
Esophageal Cancer	2	6
Fatty Liver	3	6
Hydrogen Peroxide Induced Toxicity	4	6
Leishmaniasis	4	6
Liver Cancer: Prevention	2	6
Memory Disorders	3	6
Mycobacterium Tuberculosis	5	6
Myocardial Ischemia	3	6
Candida Albicans	4	5
Candida Infection	4	5
Klebsiella Infections	4	5
Lymphoma	3	5
Mercury Poisoning	3	5
Neurodegenerative Diseases	4	5
Osteoarthritis	3	5
Staphylococcus aureus: Methicillin-resistant (MRSA)	3	5
Aflatoxicosis	2	4
Asthma	2	4
Brain Inflammation	3	4
Brain: Oxidative Stress	2	4
Cerebral Ischemia	2	4
Cervical Cancer	3	4
Chemotherapy-Induced Toxicity: Cyclophosphamide	2	4
Chronic Kidney Disease (CKD)	2	4
Colitis	2	4
Colon Cancer: Prevention	1	4
Hepatic Steatosis	2	4
Hyperglycemia	2	4
Hypertension: Pulmonary	1	4
Infection: Antibiotic Resistant	4	4
Inflammatory Bowel Diseases	2	4
Listeria Infections	4	4
Lung Injury: Acute	2	4
MRSA	2	4
Mobile Phone-Induced Oxidative Stress	2	4
Oral Cancer	3	4
Osteoporosis	2	4
Parasitic Diseases	2	4
Pseudomonas Infections	3	4
Right Ventricular Hypertrophy	1	4
Salmonella Infections	4	4
Sepsis	2	4
Sodium nitrate toxicity	2	4
Squamous cell carcinoma	3	4
Testicular Diseases	2	4
Thrombosis	3	4
Advanced Glycation End products (AGE)	2	3
Alcohol Toxicity	2	3
Alzheimer's Disease	2	3
Arsenic Poisoning	2	3
Aspergillosis	2	3
Bacterial Infections	2	3
Breast Cancer: Triple Negative	3	3
Cardiac Hypertrophy	2	3
Coronavirus Disease	2	3
Fibrosarcoma	2	3
HIV Infections	3	3
Hepatitis	2	3
Hyperuricemia	2	3
Ischemia	2	3
Promyelocytic leukemia	2	3
Prostatic Hyperplasia: Benign	2	3
Rhinovirus Infection	3	3
Streptococcus Infections	3	3
Streptococcus infections: Group A	2	3
Thyroid Cancer	3	3
Vaginal Diseases	1	3
Acetaminophen (Tylenol) Toxicity	1	2
Acinetobacter baumannii infection	1	2
Acrylamide-induced toxicity	2	2
Acute Myeloid Leukemia	2	2
Androgen Deficiency	1	2
Antibiotic Toxicity	1	2
Avian Influenza	2	2
Bacterial Prostatitis	1	2
Biliary Obstruction	1	2
Bladder Cancer	2	2
Bladder Degeneration	1	2
Bowel Stenosis	1	2
Breastfeeding Concerns: Chemical Exposure	1	2
Burns	1	2
Cachexia: Cancer	1	2
Candidiasis	2	2
Cataract	1	2
Chemical Exposure: Nitrobenzene	1	2
Chemotherapy-Induced Toxicity: Bleomycin	1	2
Chemotherapy-Induced Toxicity: Gentamicin	1	2
Cholangiocarcinoma	1	2
Chronic Pelvic Pain Syndrome	1	2
Cognitive Decline/Dysfunction	1	2
Colitis: Ulcerative	1	2
Coxsackievirus Infections	2	2
Cyanide Poisoning	1	2
Dental Caries	2	2
Diesel Exhaust Particle Toxicity	1	2
Drug-Induced Toxicity: Cyclosporine	1	2
Dysbiosis	1	2
Endothelial Damage	1	2
Enterococcus Infections	2	2
Enteropathy	1	2
Fibrosis: Liver	1	2
Fructose-Induced Toxicity	1	2
Giardiasis	1	2
Glioblastoma	2	2
Glioma	2	2
Gonorrhea	1	2
Herpes Simplex Virus Type 1	2	2
Immune Disorders: Low Immune Function	1	2
Immune Dysregulation: TH1/TH2 imbalance	1	2
Infertility: Male	1	2
Influenza	2	2
Influenza A	2	2
Insulin: Elevated	1	2
Kidney Damage	1	2
Kidney Damage: Drug-Induced	1	2
Kidney Infection	1	2
Kidney Stones	1	2
Learning disorders	1	2
Leukemia: Chronic Lymphocytic Leukemia (CLL)	1	2
Liver Cirrhosis	1	2
Liver Damage	1	2
Liver Damage: Drug-Induced	1	2
Liver Fibrosis	1	2
Liver Injury: Ischemia/reperfusion	1	2
Liver Steatosis	1	2
Liver Surgery	1	2
Lung Damage	1	2
Lung Diseases	1	2
Lymphoma: B-Cell	1	2
Lymphoma: Mantle Cell	1	2
Mastitis	1	2
Melanoma	2	2
Methicillin-resistant Staphylococcus aureus	1	2
Mitochondrial Dysfunction	1	2
Morphine Tolerance/Dependence	1	2
Myointimal Hyperplasia	1	2
Neuroblastoma	2	2
Neuropathic Pain	1	2
Parkinson's Disease	1	2
Periodontal Diseases	2	2
Pesticide Toxicity	1	2
Pesticide-Induced Toxicity: Organophosphates	1	2
Petroleum Exposure And Toxicity	1	2
Pneumococcal Infections	1	2
Prenatal Chemical Exposures	1	2
Prostatitis: Chronic	1	2
Pulmonary Fibrosis	1	2
Pyrethroid Insecticide Induced Toxicity	1	2
Radiation Induced Illness	1	2
Respiratory Infections	2	2
Smoking	1	2
Spinal Cord Injuries	1	2
Splenic Diseases	1	2
Subarachnoid hemorrhage	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Tobacco Toxicity	1	2
Tuberculosis Drug Induced Toxicity	1	2
Ulcerative Colitis	1	2
Ultraviolet Radiation Induced Damage	1	2
Upper Respiratory Infections	2	2
Urinary Tract Infections: Catheter-Associated	1	2
Vibrio Infections	2	2
Weight Problems	1	2
Acute lymphoblastic leukemia (ALL)	1	1
Adenoid cystic carcinoma (ACC)	1	1
Adenoviridae Infections	1	1
Amebiasis	1	1
Anemia: Sickle Cell	1	1
Aortic Stenosis	1	1
Aphthous Ulcer	1	1
Arterial Thickening	1	1
Ascites	1	1
Bacillus Cereus infection	1	1
Bacillus anthracis	1	1
Barrett Esophagus	1	1
Basal Cell Carcinoma	1	1
Bronchitis	1	1
Cancer Metastasis	1	1
Cancers: Drug Resistant	1	1
Canker Sore	1	1
Cardiac Mortality	1	1
Cardiomyopathy	1	1
Cardiovascular Disease: Prevention	1	1
Chemical Exposure	1	1
Chemotherapy-Induced Toxicity: Adriamycin	1	1
Cholera	1	1
Chronic Pain	1	1
Clostridium Infections	1	1
Degenerative Disk Disease	1	1
Dermatophytoses	1	1
Foodborne Pathogens: Prevention/Food Preservation	1	1
Gastrointestinal Inflammation	1	1
Gliomas	1	1
Glutathione Deficiency	1	1
Glycation	1	1
HSV-1	1	1
HSV-2	1	1
Haemophilus influenzae	1	1
Hemolytic Anemia	1	1
Hepatitis A	1	1
Hepatitis: Lectin-Induced (concanavalin)	1	1
Herpes Simplex Virus Type 2	1	1
Human Papillomavirus (HPV)	1	1
Influenza B	1	1
Leukemia: Acute myelogenous leukemia (AML)	1	1
Liver Diseases	1	1
Low Human Growth Hormone	1	1
Malaria	1	1
Micrococcus luteus infections	1	1
Multiple Myeloma	1	1
Mycotoxicity	1	1
Myocardial Infarction: Prevention	1	1
Neurologic Disorders	1	1
Osteosarcoma	1	1
Parainfluenza Virus Infections	1	1
Parasitic Intestinal Diseases	1	1
Peridontal Infection	1	1
Pneumonia	1	1
Pseudomonas fluorescens infections	1	1
Respiratory Diseases	1	1
Scars	1	1
Staphylococcal Infections	1	1
Staphylococcus epidermidis	1	1
Steptococcus Mutans Infections	1	1
Streptococcus pyogenes	1	1
Trypanosomiasis	1	1
Tuberculosis: Drug Resistant	1	1
Vesicular Stomatitis Virus	1	1

Name	AC	CK
Antioxidants	99	247
Anti-Inflammatory Agents	55	210
Chemopreventive	24	155
Antihypertensive Agents	16	105
Cardioprotective	34	101
Tumor Necrosis Factor (TNF) Alpha Inhibitor	21	99
Hypoglycemic Agents	10	98
Hypolipidemic	17	90
Anticholesteremic Agents	7	83
Anti-Bacterial Agents	39	72
Hepatoprotective	24	69
Apoptotic	46	64
Immunomodulatory	15	50
Interleukin-6 Downregulation	13	50
Antiproliferative	36	42
Gastrointestinal Agents	9	36
Neuroprotective Agents	21	36
NF-kappaB Inhibitor	14	29
Antiviral Agents	16	27
Chemoprotective Agents	13	26
Anti-Apoptotic	15	24
Renoprotective	12	24
Gastroprotective	2	22
Analgesics	3	21
Anti-atherogenic	3	21
Antimicrobial	18	21
Interleukin-1 beta downregulation	11	19
Chemotherapeutic	12	15
Anti-metastatic	9	14
Cell cycle arrest	11	13
Malondialdehyde Down-regulation	7	13
Anti-Platelet	3	12
Anticarcinogenic Agents	7	12
Antineoplastic Agents	7	12
Antiparasitic Agents	7	12
Nrf2 activation	7	12
Antifungal Agents	8	11
Chelating Agents	1	10
Cytoprotective	5	10
Detoxifier	1	10
Superoxide Dismutase Up-regulation	4	8
Autophagy Up-regulation	4	7
Chemosensitizer	3	7
Antidepressive Agents	3	6
Genoprotective	4	6
Leishmanicidal	4	6
Matrix metalloproteinase-2 (MMP-2) inhibitor	4	6
Osteoprotective	3	6
Radioprotective	3	6
Enzyme Inhibitors	3	5
Vasodilator Agents	3	5
Angiogenesis Inhibitors	3	4
Anti-Adipogenic	2	4
Anti-Glycation Agents	3	4
Antimutagenic Agents	2	4
Catalase Up-Regulation	2	4
Cyclooxygenase 2 Inhibitors	3	4
Interleukin-12 upregulation	2	4
Interleukin-4 downregulation	2	4
Matrix metalloproteinase-9 (MMP-9) inhibitor	3	4
MicroRNA modulator	4	4
Nitric Oxide Inhibitor	2	4
Quorum Sensing Inhibition	4	4
Schistosomicides	1	4
Vascular Cell Adhesion Molecule-1 Inhibitor	2	4
interleukin-13 down-regulation	2	4
Adenosine deaminase inhibitor	2	3
Anti-thrombotic	2	3
Interleukin-8 downregulation	2	3
Phase II Detoxification Enzyme Inducer	3	3
Tumor Suppressor Protein p53 Upregulation	3	3
Angiogenesis Inducing Agents	1	2
Anti-Cachexic Agents	1	2
Anti-Fibrotic	1	2
Anti-Proliferative	1	2
Antimycobacterial	1	2
Antioxidant	1	2
Bcl-2 protein down-regulation	1	2
Cytotoxic	2	2
Erythropoietic	1	2
Glutathione Upregulation	1	2
Heat Shock Protein Inducer	1	2
Heme oxygenase-1 up-regulation	1	2
Immunostimulatory	2	2
Insulin Sensitizers	1	2
Insulin-mimetic	1	2
Insulin-releasing	1	2
Interferon Gamma Reducer	1	2
Interleukin-10 upregulation	1	2
Interleukin-5 downregulation	1	2
Matrix metalloproteinase-1 (MMP-1) inhibitor	1	2
Nitric Oxide Enhancer	1	2
Pancreato Protective Agents	1	2
Photoprotective	1	2
Regenerative	1	2
STAT3 Activation	1	2
Thermogenic	1	2
Wnt/β-catenin signaling pathway modulation	2	2
Alpha-amylase inhibitor	1	1
Alpha-glucosidase inhibitor	1	1
Anti Inflammatory	1	1
Anti-Angiogenic	1	1
Autophagy Inhibitors	1	1
Bax/Bcl2 ratio: Increase	1	1
Epidermal growth factor receptor (EGFR) inhibitor	1	1
HIV-1 Integrase Inhibitor	1	1
HMG-CoA reductase inhibitor	1	1
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	1	1
Interleukin-18 down-regulation	1	1
NF-E2-Related Factor-2 (Nrf2) Modulator	1	1
Neovasculogenesis	1	1
P21 Activation	1	1
Platelet Aggregation Inhibitors	1	1
Prophylactic Agents	1	1
Radiosensitizer	1	1
STAT3 Inhibitor	1	1
Secretagogue	1	1
Telomerase Inhibitor	1	1
Tyrosinase inhibitors	1	1

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Food Nutr Res. 2017 ;61(1):1377571. Epub 2017 Sep 27. PMID: 29056888

Article Published Date : Dec 31, 2016

Study Type : Meta Analysis

Additional Links

Substances : Garlic

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Anticholesteremic Agents, Hypoglycemic Agents, Hypolipidemic

Additional Keywords : Plant Extracts

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Garlic intake could reduce the risk of colorectal cancer.Dec 31, 2019

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Pubmed Data : Medicine (Baltimore). 2020 Jan ;99(1):e18575. PMID: 31895803

Article Published Date : Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Eur J Clin Nutr. 2013 Jan ;67(1):64-70. Epub 2012 Nov 21. PMID: 23169470

Article Published Date : Dec 31, 2012

Study Type : Human Study

Additional Links

Substances : Garlic

Diseases : Hypertension

Pharmacological Actions : Antihypertensive Agents

Additional Keywords : Plant Extracts

[+]

Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis.Feb 01, 2004

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Pubmed Data : Breast Cancer Res Treat. 2004 Feb;83(3):221-31. PMID: 19573556

Article Published Date : Feb 01, 2004

Study Type : Human Study

Additional Links

Substances : Arginine, B-complex, Garlic, Vitamin B-12

Diseases : Arterial Calcification, Atherosclerosis, Hypertension

Pharmacological Actions : Cardioprotective

Additional Keywords : Plant Extracts

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Aged garlic extract with supplement is associated with increase in brown adipose, decrease in white adipose tissue and predict lack of progression in coronary atherosclerosis.Feb 28, 2013

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Pubmed Data : Int J Cardiol. 2013 Mar 1. Epub 2013 Mar 1. PMID: 23453866

Article Published Date : Feb 28, 2013

Study Type : Human Study

Additional Links

Substances : Garlic

Diseases : Arterial Calcification, Coronary Artery Disease, High Homocysteine

Pharmacological Actions : Cardioprotective

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Allicin extract and sodium bicarbonate may be suitable as drug alternatives in prevention of thrush in newborn infants. Jan 01, 1992

Pubmed Data : Int J Mol Sci. 2016 ;17(8). Epub 2016 Aug 11. PMID: 27529226

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Garlic, Grape Seed Extract, Green Tea

Diseases : Atherosclerosis, Cardiovascular Diseases

Pharmacological Actions : Anti-atherogenic

Additional Keywords : Plant Extracts, Risk Reduction

[+]

Chronic garlic powder intake attenuated age-related increases in aortic stiffness.Oct 21, 1997

Article Published Date : Jan 27, 2020

Study Type : Human Study

Additional Links

Substances : Garlic

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective, Hypolipidemic

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Pubmed Data : Wien Med Wochenschr. 1999;149(8-10):217-24. PMID: 10483684

Article Published Date : Jan 01, 1999

Study Type : Human Study

Additional Links

Substances : Garlic

Diseases : Arterial Plaque, Arteriosclerosis, Fibrinogen: Elevated, Heart Attack, Intima Media Thickening , Myocardial Infarction, Stroke: Prevention

Additional Keywords : Disease Regression

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Garlic seems safer clinically and as effective as d-penicillamine for removing lead from the body.Apr 30, 2012

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Pubmed Data : Basic Clin Pharmacol Toxicol. 2012 May ;110(5):476-81. Epub 2011 Dec 29. PMID: 22151785

Article Published Date : Apr 30, 2012

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Pubmed Data : J Breast Cancer. 2016 09 ;19(3):292-300. Epub 2016 Sep 23. PMID: 27721879

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Garlic, Leek

Diseases : Breast Cancer

Pharmacological Actions : Chemopreventive

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Impact of garlic tablets on nosocomial infections in hospitalized patients in intensive care units.Mar 31, 2017

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Synergism of allicin in combination with itraconazole and terbinafine, which could be a reference for the treatment of tinea capitis due to M. canis.Dec 31, 2020

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Pubmed Data : Front Med (Lausanne). 2021 ;8:783086. Epub 2021 Nov 26. PMID: 34901093

Allicin reduces inflammation by regulating ROS/NLRP3 and autophagy in the context of A. fumigatus infection in mice.Aug 07, 2020

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Pubmed Data : Gene. 2020 Aug 8 ;762:145042. Epub 2020 Aug 8. PMID: 32777529

Article Published Date : Aug 07, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Allicin

Diseases : Aspergillosis, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents

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"Aged garlic extract inhibits development of putative preneoplastic lesions in rat hepatocarcinogenesis."Mar 01, 2006

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Pubmed Data : J Nutr. 2006 Mar ;136(3 Suppl):855S-860S. PMID: 16484580

Article Published Date : Mar 01, 2006

Study Type : Animal Study

Additional Links

Substances : Garlic

Diseases : Liver Cancer: Prevention

Pharmacological Actions : Chemopreventive

Additional Keywords : Plant Extracts

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"Chronic nicotine toxicity is prevented by aqueous garlic extract."Jun 01, 2005

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Pubmed Data : Plant Foods Hum Nutr. 2005 Jun ;60(2):77-86. PMID: 16021835

Article Published Date : Jun 01, 2005

Study Type : Animal Study

Additional Links

Substances : Garlic

Diseases : Nicotine/Tobacco Toxicity , Oxidative Stress

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation

Additional Keywords : Plant Extracts

Problem Substances : Nicotine

Adverse Pharmacological Actions : Oxidant

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"Garlic and vitamin E provides antioxidant defence in tissues of female rats treated with nicotine."Jan 01, 2011

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Pubmed Data : Niger J Physiol Sci. 2011 ;26(1):103-7. Epub 2011 Nov 23. PMID: 22314996

Article Published Date : Jan 01, 2011

Study Type : Animal Study

Additional Links

Substances : Garlic, Vitamin E

Diseases : Nicotine/Tobacco Toxicity , Oxidative Stress

Pharmacological Actions : Antioxidants

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2.4 GHz electromagnetic field exposure increases DNA oxidation in brain and plasma and plasma protein oxidation in rats. Garlic reduces biomarkers of both DNA and protein oxidation, suggesting it protects against the adverse effects of EMF radiation.Oct 01, 2014

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Pubmed Data : Int J Radiat Biol. 2014 Oct ;90(10):892-6. Epub 2014 Jun 25. PMID: 24844368

Article Published Date : Oct 01, 2014

Aged garlic extract protects against doxorubicin-induced cardiotoxicity in rats.Feb 01, 2006

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Pubmed Data : Nutrition. 2006 Feb;22(2):136-45. PMID: 20060872

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Pubmed Data : Life Sci. 2019 Jun 3. Epub 2019 Jun 3. PMID: 31170417

Allicin attenuated chronic social defeat stress induced depressive-like behaviorsDec 31, 2018

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Pubmed Data : Metab Brain Dis. 2019 02 ;34(1):319-329. Epub 2018 Dec 4. PMID: 30515710

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Allicin

Diseases : Depression

Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents

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Allicin attenuated depressive-like behaviours triggered by long-term high fat diet consumption.Jun 13, 2019

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Pubmed Data : Metab Brain Dis. 2019 Jun 14. Epub 2019 Jun 14. PMID: 31201726

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Pubmed Data : Mol Med Rep. 2018 Mar 7. Epub 2018 Mar 7. PMID: 29512749

Article Published Date : Mar 06, 2018

Study Type : Animal Study

Additional Links

Substances : Allicin

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Allicin attenuates liver oxidative stress and inflammation.Sep 27, 2016

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Pubmed Data : J Agric Food Chem. 2016 Sep 28 ;64(38):7104-13. Epub 2016 Sep 19. PMID: 27584700

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Pubmed Data : Nutrients. 2019 Dec 2 ;11(12). Epub 2019 Dec 2. PMID: 31810206

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Pubmed Data : iScience. 2020 May 22 ;23(5):101113. Epub 2020 Apr 28. PMID: 32413611

Article Published Date : May 21, 2020

Study Type : Animal Study

Additional Links

Substances : Allicin

Diseases : Hepatic Steatosis, Obesity

Pharmacological Actions : Hepatoprotective

Additional Keywords : Anti-Obesity Agents

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Allicin is highly effective in the treatment and prevention of acrylamide-induced intestinal injury.Oct 24, 2021

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Pubmed Data : J Agric Food Chem. 2021 Oct 25. Epub 2021 Oct 25. PMID: 34694121

Problem Substances : Arsenic Trioxide

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Allicin regulates Treg/Th17 balance in mice with collagen-induced arthritis.Apr 30, 2021

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Pubmed Data : FASEB J. 2020 Jul 3. Epub 2020 Jul 3. PMID: 32619085

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Pubmed Data : Mol Nutr Food Res. 2017 Mar 30. Epub 2017 Mar 30. PMID: 28371322

Article Published Date : Mar 29, 2017

Study Type : Animal Study

Additional Links

Substances : Garlic

Diseases : Colitis, Inflammatory Bowel Diseases, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents

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Allium sativum had the same efficacy in inhibiting myointimal hyperplasia when compared to the positive control, cilostazol.Jun 30, 2016

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Pubmed Data : J Oral Pathol Med. 2002 Mar ;31(3):142-6. PMID: 11903819

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Pubmed Data : J Food Biochem. 2019 Dec 26:e13126. Epub 2019 Dec 26. PMID: 31877235

Article Published Date : Dec 25, 2019

Study Type : Animal Study

Additional Links

Substances : Garlic

Diseases : Hydrogen Peroxide Induced Toxicity, Hypertension, Oxidative Stress

Pharmacological Actions : Antihypertensive Agents, Antioxidants

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Antischistosomal and anti-inflammatory activity of garlic and allicin compared with that of praziquantel in vivo.Apr 26, 2018

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Pubmed Data : BMC Complement Altern Med. 2018 Apr 27 ;18(1):135. Epub 2018 Apr 27. PMID: 29703259

Cytoprotective potential of aged garlic extract and its active constituent, S-allyl-l-cysteine, in presence of carvedilol during isoproterenol-induced myocardial disturbance.May 26, 2021

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Pubmed Data : J Environ Pathol Toxicol Oncol. 2018 ;37(4):291-303. PMID: 30806236

Article Published Date : Dec 31, 2017

Study Type : Animal Study

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Substances : Garlic, Organosulfur Compounds

Diseases : Rheumatoid Arthritis

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Phytotherapy, Plant Extracts

Problem Substances : Freund adjuvant

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Diallyl disulfide mitigates DNA damage and spleen tissue effects after irradiation.Nov 23, 2019

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Pubmed Data : Int J Biol Sci. 2017 ;13(2):167-178. Epub 2017 Jan 15. PMID: 28255269

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Garlic

Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Lung Cancer

Pharmacological Actions : Chemoprotective Agents, Chemotherapeutic

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Pubmed Data : Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2019 Feb 28 ;41(1):43-52. PMID: 30837041

Article Published Date : Feb 27, 2019

Study Type : Animal Study

Additional Links

Substances : Garlic, Organosulfur Compounds

Diseases : Ovarian Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

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Endurance exercises and consumption of garlic supplement have been proved to be an extremely effective treatment for breast cancer patients.Dec 31, 2021

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Pubmed Data : Int J Prev Med. 2022 ;13:38. Epub 2022 Mar 12. PMID: 35529512

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Garlic

Diseases : Breast Cancer

Therapeutic Actions : Exercise: Endurance

Pharmacological Actions : Anti-Inflammatory Agents

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Fermented black garlic could be used for reducing the risk of cardiovascular disease.Oct 06, 2019

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Pubmed Data : J Agric Food Chem. 2019 Oct 7. Epub 2019 Oct 7. PMID: 31588747

Article Published Date : Oct 06, 2019

Study Type : Animal Study

Additional Links

Substances : Fermented Foods and Beverages, Garlic

Diseases : Cardiovascular Diseases, Hydrogen Peroxide Induced Toxicity

Pharmacological Actions : Angiogenesis Inducing Agents, Anti-Apoptotic, Cardioprotective

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Fermented garlic ameliorates hypercholesterolemia and inhibits platelet activation.Dec 31, 2018

Garlic and onion have anti-lithogenic activity in formation of cholesterol gallstones. Jan 14, 2010

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Pubmed Data : Steroids. 2010 Jan 14. Epub 2010 Jan 14. PMID: 20079366

Article Published Date : Jan 14, 2010

Study Type : Animal Study

Additional Links

Substances : Garlic, Onion

Diseases : Gallstones

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Garlic and onion have antithrombotic activity. Nov 01, 2002

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Pubmed Data : J Nutr. 2002 Nov;132(11):3263-71. PMID: 8860105

Article Published Date : Nov 01, 2002

Study Type : Animal Study

Additional Links

Substances : Garlic, Onion

Diseases : Thrombosis

Pharmacological Actions : Anti-thrombotic

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Garlic and onion oil have anti-obesity properties that can counteract the effects of a high fat diet.Dec 31, 2017

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Pubmed Data : Nutr Metab (Lond). 2018 ;15:43. Epub 2018 Jun 20. PMID: 29951108

Garlic extract alleviates liver fibrosis and oxidative damage induced by biliary obstruction in rats. Apr 15, 2005

Study Type : Animal Study

Additional Links

Substances : Garlic

Diseases : Aflatoxicosis

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Garlic extract prevents selenite-induced cataractogenesis in rats. Oct 01, 2009

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Pubmed Data : J Ocul Pharmacol Ther. 2009 Oct;25(5):395-400. PMID: 19857100

Pubmed Data : Nutr Metab (Lond). 2011 ;8:53. Epub 2011 Jul 27. PMID: 21794123

Article Published Date : Jan 01, 2011

Garlic oil extract has activity against S. japonicum larvae and a promising preventive efficacy against S. japonicum infection.Dec 31, 2016

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Pubmed Data : Asian Pac J Cancer Prev. 2009;10(5):827-31. PMID: 20104973

Article Published Date : Jan 01, 2009

Study Type : Animal Study

Additional Links

Substances : Garlic

Diseases : Colon Cancer

Pharmacological Actions : Chemopreventive

[+]

Hypertensive vascular and cardiac remodeling protection by allicin in spontaneous hypertension rats via CaMK Ⅱ/NF-κB pathway.Oct 31, 2022

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Pubmed Data : Dermatol Surg. 2017 Oct 26. Epub 2017 Oct 26. PMID: 29077629

Article Published Date : Oct 25, 2017

Study Type : Animal Study

Additional Links

Substances : Garlic

Diseases : Wound Healing

[+]

Modulation of allicin-free garlic on gut microbiomeFeb 04, 2020

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Pubmed Data : Biometals. 2008 Dec;21(6):623-33. Epub 2008 Jun 3. PMID: 18521705

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View the Evidence: 631 Abstracts with Garlic Research

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The association of garlic intake and cardiovascular risk factors.Mar 28, 2022

Allicin as an add-on therapy improves H. pylori eradication, healing of ulcers, and remission of symptoms.Oct 20, 2019

Allium vegetable consumption and health: An umbrella review of meta-analyses of multiple health outcomes.Jul 31, 2019

Anti-hyperlipidemia of garlic by reducing the level of total cholesterol and low-density lipoprotein.Apr 30, 2018

Current data confirmed that garlic supplementation would reduce serum C-reactive protein levels.Jan 31, 2019

Current data confirms that garlic supplement plays positive rolls in the management of T2DM.Dec 31, 2016

Effects of garlic extract on lipid profile in patients with coronary artery disease.Oct 08, 2021

Effects of garlic supplementation on liver enzymes: A systematic review and meta-analysis of randomized controlled trials.Jul 31, 2020

Effects of garlic supplementation on oxidative stress and antioxidative capacity biomarkers.Jan 22, 2021

Garlic and grape seed supplement use is inversely associated with hematological malignancies.Jul 29, 2011

Garlic can reduce lipid profile as well as glucose parameters in patients suffering from cardiovascular diseases and diabetes.Dec 31, 2018

Garlic intake could reduce the risk of colorectal cancer.Dec 31, 2019

Garlic reduces triglyceride levels. Jun 01, 2009

Garlic supplementation reduces circulating C-reactive protein, tumor necrosis factor, and interleukin-6 in adults.Mar 31, 2019

Garlic supplements may be considered as a treatment option for hypertension, slightly elevated cholesterol, and stimulation of immunity.Jan 31, 2016

The association of garlic with Helicobacter pylori infection and gastric cancer risk: A systematic review and meta-analysis.Sep 30, 2018

The consumption of large amounts of Allium vegetables reduces the risk for gastric cancer. Jul 01, 2011

The present review and meta-analysis suggests that garlic is an effective and safe approach for treating hypertension.Mar 14, 2015

These findings suggested that current evidence may support garlic as an adjunct to pharmacological management of metabolic diseases.Feb 11, 2020

This meta-analysis showed that supplementation with garlic could reduce the level of circulating C-reactive protein.Jun 18, 2020

This meta-analysis showed that the administration of garlic resulted in a significant reduction in fasting blood glucose concentrations.Dec 31, 2014

This study identified the association between garlic intake and reduced risk of gastric and colorectal cancers.Mar 31, 2022

A 12-week garlic supplementation had beneficial effects on symptom relief in overweight or obese women with knee osteoarthritis.May 31, 2018

A combination of garlic, mullein, calendula, st. johns wort and olive oil is as effective as an anesthetic drug for the management of acute otitis media-associated pain. Jul 01, 2001

AGE has the ability to stabilize vulnerable plaque and decrease adverse cardiovascular events.Jan 31, 2016

Aged Garlic Extract (AGE) inhibits the rate of progression of coronary calcification in patients receiving statin therapy. Nov 01, 2004

Aged garlic extract prevents a decline of NK cell number and activity in patients with advanced cancer.Mar 01, 2006

Aged garlic extract reduces blood pressure in hypertensives: a dose-response trial.Dec 31, 2012

Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis.Feb 01, 2004

Aged garlic extract with supplement is associated with increase in brown adipose, decrease in white adipose tissue and predict lack of progression in coronary atherosclerosis.Feb 28, 2013

Allicin extract and sodium bicarbonate may be suitable as drug alternatives in prevention of thrush in newborn infants. Jan 01, 1992

Allicin improves carotid artery intima-media thickness in coronary artery disease patients with hyperhomocysteinemia.Jul 31, 2017

Allium vegetables are associated with reduced risk of colorectal cancer.Feb 19, 2019

Allium vegetables are related to decreased risk of prostate cancer. Dec 31, 2012

Allium vegetables intake and the risk of gastric cancer.Dec 31, 2021

An isoflavonoid-rich herbal preparation Karinat may play an important role in the prevention of atherosclerosis progression in postmenopausal women.Dec 31, 2015

Chronic garlic powder intake attenuated age-related increases in aortic stiffness.Oct 21, 1997

Daily consumption of aged garlic extract benefits oral health by reducing gingival inflammation and gingival bleeding.May 31, 2018

Effect of garlic essential oil in 97 patients hospitalized with covid-19: A multi-center experience.Jun 30, 2022

Effect of garlic powder supplementation on hepatic steatosis, liver enzymes and lipid profile in patients with non-alcoholic fatty liver disease.Jan 27, 2020

Effects of Allium sativum (Garlic) on systolic and diastolic blood pressure in patients with essential hypertension.Aug 31, 2013

Fermented garlic extracts might be effective and safe management options for mild hepatic dysfunction.Jul 31, 2017

Garlic could be a suitable alternative for metronidazole in treatment of BV in those interested in herbal medicines or those affected by side effects of metronidazole.Jun 30, 2014

Garlic extract favorably modifies markers of endothelial function in obese patients.May 31, 2018

Garlic extract had beneficial effects on serum inflammatory markers of peritoneal dialysis patients.Jan 24, 2019

Garlic extract has potent antiviral activity against human cytomegalovirus. Feb 01, 1993

Garlic gel increases the efficacy of betamethasone valerate cream in the treatment of localized alopecia areata. Jan 01, 2007

Garlic has a therapeutic effect in intermittent claudication. May 01, 1993

Garlic improves metabolic syndrome components, insulin resistance, fatty liver index, and appetite.May 10, 2021

Garlic improves metformin therapy in type 2 diabetics. Oct 01, 2011

Garlic may improve arterial oxygenation and symptoms in patients with hepatopulmonary syndrome. Oct 01, 1998

Garlic may increase oxygenation and improve dyspnea in children with hepatopulmonary syndrome.Apr 21, 2006

Garlic may provide an ideal alternative to acetylsalicylic acid (aspirin) in arteriosclerosis prevention. Apr 01, 2008

Garlic may reduce the amount of fat in the liver and prevent or delay the progression of NAFLD.Dec 31, 2015

Garlic moxibustion has a therapeutic effect in patients with tuberculosis. Jan 01, 2009

Garlic plus lemon juice resulted in an improvement in lipid levels, fibrinogen and blood pressure of patients with hyperlipidemia.Dec 31, 2015

Garlic powder supplementation improved risk factors of NAFLD. May 31, 2020

Garlic reduces a multitude of risk factors associated with arteriosclerosis and significantly reduces the risk for heart attack and stroke. Jan 01, 1999

Garlic seems safer clinically and as effective as d-penicillamine for removing lead from the body.Apr 30, 2012

Garlic supplementation by improving inflammatory mediators and clinical symptoms can be considered as a potential adjunct treatment in patients with RA.Oct 31, 2020

Garlic supplementation for 12 weeks might reduce pain severity in overweight or obese women with knee osteoarthritis.Sep 14, 2018

Garlic supplementation for 8 weeks resulted in significant improvements in oxidative stress in women with rheumatoid arthritis.Mar 10, 2020

Habitual consumption of garlic was associated with a lower all-cause mortality risk.Jun 29, 2019

High consumption of certain Allium vegetables may reduce the risk of breast cancer.Dec 31, 2015

Impact of garlic tablets on nosocomial infections in hospitalized patients in intensive care units.Mar 31, 2017

Long-term symptomatic group B streptococcal vulvovaginitis: eight cases resolved with freshly cut garlic.Sep 01, 2009

Naturopathic treatment for ear pain is demonstrated superior to antibiotic treatment.May 01, 2003

Onion and garlic consumption has a mildly protective role against the risk of endometrial cancer. Sep 01, 2009

Onion and garlic use is inversely associated with human cancer. Nov 01, 2006

Preparation and optimization of garlic oil/apple vider vinegar nanoemulsion loaded with minoxidil to treat alopecia.Dec 13, 2021

Raw crushed garlic has beneficial effects on components of metabolic syndrome.Jul 03, 2018

Garlic

View the Evidence:
631 Abstracts with Garlic Research