Garlic: Aged

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59 Diseases Researched for Garlic: Aged
NameACCKFocus
Cardiovascular Diseases863Locked
Hypertension652Locked
Atherosclerosis744Locked
Oxidative Stress835Locked
Inflammation625Locked
Diabetes Mellitus: Type 2322Locked
Coronary Artery Disease212Locked
Arterial Calcification110Locked
Arterial Hardening: Elasticity110Locked
C-Reactive Protein110Locked
Cold and Flu110Locked
Diabetic Complications110Locked
Endothelial Damage110Locked
Endothelial Dysfunction110Locked
High Cholesterol110Locked
Hypercholesterolemia110Locked
Marfan Syndrome110Locked
Obesity110Locked
Periodontitis110Locked
Warts: Common110Locked
Chemically-Induced Liver Damage36Locked
Endometriosis26Locked
Chemotherapy-Induced Toxicity: Cisplatin24Locked
Cognitive Decline/Dysfunction24Locked
Liver Damage24Locked
Cerebral Ischemia23Locked
Colon Cancer23Locked
Colon Cancer: Prevention23Locked
Alcohol Toxicity 12Locked
Allergies12Locked
Alzheimer's Disease22Locked
Anaphylaxis12Locked
Drug-Induced Toxicity: Gastrointestinal12Locked
Drug-Induced Toxicity: Indomethacin12Locked
Fatty Liver12Locked
Fibrosarcoma12Locked
Gastric Ulcer12Locked
Gastrointestinal Inflammation12Locked
High Fat Diet12Locked
IgE-Mediated Hypersensitivity12Locked
Ischemia12Locked
Kidney Damage12Locked
Kidney Damage: Chemically-Induced12Locked
Liver Fibrosis12Locked
Metabolic Syndrome X12Locked
Nonalcoholic fatty liver disease (NAFLD)12Locked
Pulmonary Fibrosis: Bleomycin-Induced12Locked
Spinal Cord Injuries12Locked
Brain Inflammation 11Locked
Breast Cancer11Locked
Candida Albicans11Locked
Escherichia coli Infections11Locked
Huntington Disease11Locked
Hypoxia11Locked
Infection: Antibiotic Resistant11Locked
Leukemia11Locked
Lipopolysaccharide-Induced Toxicity11Locked
Neuroblastoma11Locked
Parkinson's Disease11Locked
42 Pharmacological Actions Researched for Garlic: Aged
NameACCKFocus
Anti-Inflammatory Agents2193Locked
Cardioprotective974Locked
Antihypertensive Agents762Locked
Antioxidants2361Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor842Locked
Interleukin-6 Downregulation638Locked
Anti-atherogenic322Locked
Immunomodulatory322Locked
Antiproliferative 612Locked
Hypoglycemic Agents212Locked
Vasoprotective212Locked
Anti-Bacterial Agents110Locked
Anticholesteremic Agents110Locked
Dermatologic Agents110Locked
Hepatoprotective510Locked
Nrf2 activation39Locked
NF-kappaB Inhibitor38Locked
Neuroprotective Agents58Locked
Anti-Apoptotic47Locked
Heme oxygenase-1 up-regulation26Locked
Cell cycle arrest15Locked
Chemopreventive35Locked
Vascular Cell Adhesion Molecule-1 Inhibitor 15Locked
Apoptotic44Locked
Chemoprotective Agents24Locked
Renoprotective24Locked
Antimicrobial23Locked
Anti-Allergic Agents12Locked
Anti-Fibrotic12Locked
Anti-Ulcer Agents12Locked
Anticarcinogenic Agents12Locked
Cyclooxygenase 2 Inhibitors12Locked
Gastroprotective12Locked
Bcl-2 protein down-regulation11Locked
Caspase-3 Activation11Locked
Caspase-8 activation11Locked
Chemotherapeutic11Locked
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor11Locked
NF-E2-Related Factor-2 (Nrf2) Modulator11Locked
Nitric Oxide Inhibitor11Locked
Platelet Aggregation Inhibitors11Locked
Prophylactic Agents11Locked

View the Evidence:
63 Abstracts with Garlic: Aged Research

[+]

Kyolic aged garlic extract is considered to be highly tolerable with a high safety profile either as a stand-alone or adjunctive anti-hypertensive treatment.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2020 Feb ;19(2):1472-1478. Epub 2019 Dec 27. PMID: 32010325
Article Published Date : Jan 31, 2020
Study Type : Meta Analysis, Review
Additional Links
Substances : Garlic: Aged
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents
[+]

ABG supplementation reduced atherogenic markers and thus may have a cardioprotective effect beyond the gold standard medication in patients with mild hypercholesterolemia.Aug 31, 2014

Pubmed Data : Nutrition. 2014 Sep ;30(9):1034-9. Epub 2014 Mar 12. PMID: 24976429
Article Published Date : Aug 31, 2014
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : High Cholesterol, Hypercholesterolemia
Pharmacological Actions : Anticholesteremic Agents, Cardioprotective
Additional Keywords : Significant Treatment Outcome
[+]

AGE supplementation may enhance immune cell function and may be partly responsible for the reduced severity of colds and flu reported.Jan 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr. 2016 Feb ;146(2):433S-6S. Epub 2016 Jan 13. PMID: 26764332
Article Published Date : Jan 31, 2016
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Cold and Flu
Pharmacological Actions : Immunomodulatory
[+]

AGE+CoQ10 are associated with beneficial effects on inflammatory markers and reduced progression of coronary atherosclerosis.Jun 30, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cardiovasc Dis Res. 2012 Jul ;3(3):185-90. PMID: 22923934
Article Published Date : Jun 30, 2012
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10, Garlic: Aged
Diseases : Atherosclerosis, Coronary Artery Disease
Pharmacological Actions : Anti-atherogenic, Anti-Inflammatory Agents
Additional Keywords : Risk Reduction
[+]

Aged garlic extract and coenzyme Q10 have a beneficial effect on vascular elasticity and endothelial function in firefighters with high occupational stress. Jul 31, 2012

Pubmed Data : Nutrition. 2012 Aug 1. Epub 2012 Aug 1. PMID: 22858191
Article Published Date : Jul 31, 2012
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10, Garlic: Aged
Diseases : Arterial Hardening: Elasticity, Atherosclerosis, Endothelial Dysfunction
[+]

Aged garlic extract has a positive impact on endothelial function in patients with T2DM.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2020 Feb ;19(2):1485-1489. Epub 2019 Dec 27. PMID: 32010327
Article Published Date : Jan 31, 2020
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Diabetes Mellitus: Type 2, Endothelial Damage
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Aged garlic extract inhibits coronary artery calcification progression, lowers IL–6, glucose levels and blood pressure.Apr 28, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2020 Apr 29 ;20(1):132. Epub 2020 Apr 29. PMID: 32349742
Article Published Date : Apr 28, 2020
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Atherosclerosis, Cardiovascular Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antihypertensive Agents, Cardioprotective, Hypoglycemic Agents, Interleukin-6 Downregulation
[+]

Aged garlic extract may be beneficial in preventing the development of chronic diseases associated with low-grade inflammation.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Nutr ESPEN. 2018 04 ;24:148-155. Epub 2018 Jan 3. PMID: 29576354
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : C-Reactive Protein, Inflammation, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Aged garlic extract may exert several positive direct effects on the development and progression of cardiovascular diseases.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2020 Feb ;19(2):1490-1499. Epub 2019 Dec 27. PMID: 32010328
Article Published Date : Jan 31, 2020
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Cardiovascular Diseases
Pharmacological Actions : Cardioprotective, Vasoprotective
[+]

Aged garlic extract preserves cutaneous microcirculation in patients with increased risk for cardiovascular diseases.Sep 12, 2019

Pubmed Data : Int Wound J. 2019 Sep 13. Epub 2019 Sep 13. PMID: 31518044
Article Published Date : Sep 12, 2019
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Cardiovascular Diseases
Pharmacological Actions : Cardioprotective
Additional Keywords : Risk Reduction
[+]

Aged garlic extract reduces left ventricular myocardial mass in patients with diabetes.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2020 Feb ;19(2):1468-1471. Epub 2019 Dec 27. PMID: 32010324
Article Published Date : Jan 31, 2020
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Diabetic Complications
Pharmacological Actions : Cardioprotective
[+]

Aged garlic extract reduces low attenuation plaque in coronary arteries of patients with diabetes.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2020 Feb ;19(2):1457-1461. Epub 2019 Dec 27. PMID: 32010322
Article Published Date : Jan 31, 2020
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Arterial Calcification, Atherosclerosis, Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-atherogenic
[+]

Aged garlic extract was highly tolerable with a high safety profile as a stand-alone or adjunctive antihypertensive treatment.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Blood Press Control. 2016 ;9:9-21. Epub 2016 Jan 27. PMID: 26869811
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Cardiovascular Diseases, Hypertension
Pharmacological Actions : Anti-Inflammatory Agents, Antihypertensive Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts, Risk Reduction
[+]

Antihypertensive effects of an optimized aged garlic extract in subjects with grade I hypertension.Aug 22, 2023

Pubmed Data : Nutrients. 2023 Aug 23 ;15(17). Epub 2023 Aug 23. PMID: 37686723
Article Published Date : Aug 22, 2023
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents
Additional Keywords : Medication Reduction
[+]

Beneficial effect of aged garlic extract on periodontitis.Oct 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Biochem Nutr. 2020 Nov ;67(3):297-301. Epub 2020 Jul 31. PMID: 33293771
Article Published Date : Oct 31, 2020
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Periodontitis
Pharmacological Actions : Anti-Bacterial Agents
[+]

Effects of an optimized aged garlic extract on cardiovascular disease risk factors.Jan 17, 2022

Pubmed Data : Nutrients. 2022 Jan 18 ;14(3). Epub 2022 Jan 18. PMID: 35276764
Article Published Date : Jan 17, 2022
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Cardiovascular Diseases
Pharmacological Actions : Cardioprotective
Additional Keywords : Risk Reduction
[+]

Garlic supplementation increased the activity of antioxidant enzymes and could possibly decrease exercise-induced oxidative damage in male athletes.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Oral Biol Craniofac Res. 2015 Sep-Dec;5(3):146-152. Epub 2015 Aug 21. PMID: 26605139
Article Published Date : Aug 31, 2015
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Oxidative Stress
Therapeutic Actions : Exercise
Pharmacological Actions : Antioxidants
Additional Keywords : Supplementation
[+]

Kyolic-aged-garlic-extract is effective in reducing blood pressure in patients with uncontrolled hypertension.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2018 ;5:122. Epub 2018 Dec 11. PMID: 30619868
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Hypertension
Pharmacological Actions : Anti-Inflammatory Agents, Antihypertensive Agents
[+]

Lipid garlic extract is effective and a safe modality with good cure rates for treatment of recalcitrant multiple common warts.Aug 31, 2014

Pubmed Data : Dermatol Ther. 2014 Sep-Oct;27(5):272-7. Epub 2014 Jun 9. PMID: 24910383
Article Published Date : Aug 31, 2014
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Warts: Common
Pharmacological Actions : Dermatologic Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs
[+]

Oxidative stress in plasma from patients with Marfan syndrome is modulated by deodorized garlic preliminary findings.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2022 ;2022:5492127. Epub 2022 Jan 17. PMID: 35082968
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Marfan Syndrome, Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

The present study concludes that AGE lowers IL-6 in females with a risk profile of cardiovascular disease.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:6636875. Epub 2021 Mar 31. PMID: 33868439
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Cardiovascular Diseases, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-6 Downregulation
[+]

Aged garlic extract enhances heme oxygenase-1 and glutamate-cysteine ligase modifier subunit expression in human endothelial cells.Jan 31, 2016

Pubmed Data : Nutr Res. 2016 Feb ;36(2):143-9. Epub 2015 Oct 24. PMID: 26507778
Article Published Date : Jan 31, 2016
Study Type : Human In Vitro
Additional Links
Substances : Garlic: Aged
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
[+]

These results suggest that HEABG may be effective in the prevention and treatment of endometriosis in humans.Jun 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2013 Jul ;32(1):67-78. Epub 2013 Apr 25. PMID: 23619991
Article Published Date : Jun 30, 2013
Study Type : Human In Vitro
Additional Links
Substances : Garlic: Aged
Diseases : Endometriosis
Pharmacological Actions : Antiproliferative , Cell cycle arrest, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Cell Adhesion Molecule-1 Inhibitor
Additional Keywords : Plant Extracts
[+]

AGE corrected the histopathological abnormalities in gastric tissue and proved a promising gastroprotective role in gastric ulcer.Jun 30, 2016

Pubmed Data : Nutrition. 2016 Jul-Aug;32(7-8):849-54. Epub 2016 Jan 21. PMID: 27158056
Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Antioxidants, Gastroprotective
Additional Keywords : Plant Extracts
[+]

AGE exhibits a dose-dependent ameliorative action on indicators of diabetes in STZ-induced diabetic rats.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2016 ;16(1):17. Epub 2016 Jan 19. PMID: 26786785
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Hypoglycemic Agents
Additional Keywords : Dose Response
[+]

AGE has an ameliorative effect against CP-induced oxidative stress and renal damage through its antioxidant, anti-inflammatory and antiapoptotic properties. Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Cell Int. 2014 ;14(1):92. Epub 2014 Sep 28. PMID: 25298749
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, Renoprotective
Additional Keywords : Plant Extracts
[+]

AGE showed synergistic effects with NTX on inhibition of tumor growth and increment of survival times.Jun 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacognosy Res. 2013 Jul ;5(3):189-94. PMID: 23901215
Article Published Date : Jun 30, 2013
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Fibrosarcoma
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Antiproliferative , Chemopreventive
Additional Keywords : Natural Substance/Drug Synergy, Plant Extracts
[+]

Aged black garlic has hepatoprotective effects and suggests that supplementation might be a good adjuvant therapy for the management of liver injury.Feb 28, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Res. 2014 Mar ;30(1):49-54. PMID: 24795800
Article Published Date : Feb 28, 2014
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Fatty Liver, High Fat Diet, Liver Damage
Pharmacological Actions : Hepatoprotective
[+]

Aged garlic ethyl acetate extract may therefore be a beneficial food for protecting against neurodegeneration such as Alzheimer's disease.May 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Prev Nutr Food Sci. 2019 Jun ;24(2):165-170. Epub 2019 Jun 30. PMID: 31328121
Article Published Date : May 31, 2019
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Aged garlic extract and S-allylcysteine increase the GLUT3 and GCLC expression levels in cerebral ischemia.Nov 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Clin Exp Med. 2019 Dec ;28(12):1609-1614. PMID: 31851788
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
[+]

Aged garlic extract attenuates neuronal injury in a rat model of spinal cord ischemia/reperfusion injury.May 31, 2016

Pubmed Data : J Med Food. 2016 Jun ;19(6):601-6. Epub 2016 May 16. PMID: 27183321
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Ischemia, Spinal Cord Injuries
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Plant Extracts
[+]

Aged garlic extract exhibited antioxidant effect that could ameliorate the nephrotoxic effects of cisplatin.Mar 21, 2015

Pubmed Data : Microsc Res Tech. 2015 Mar 22. Epub 2015 Mar 22. PMID: 25810378
Article Published Date : Mar 21, 2015
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Oxidative Stress
Pharmacological Actions : Antioxidants, Chemoprotective Agents
[+]

Aged garlic extract prevents alcohol-induced cytotoxicity.Apr 30, 2023

Pubmed Data : Mol Nutr Food Res. 2023 May ;67(10):e2200627. Epub 2023 Mar 23. PMID: 36856009
Article Published Date : Apr 30, 2023
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Alcohol Toxicity , Chemically-Induced Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective, Nrf2 activation
[+]

Aged garlic extract reduces metabolic syndrome induced cardiovascular risk, through its anti-oxidant properties.Oct 25, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2016 Oct 26 ;21(11). Epub 2016 Aug 26. PMID: 27792195
Article Published Date : Oct 25, 2016
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Metabolic Syndrome X
Pharmacological Actions : Antioxidants, Cardioprotective
[+]

Aged garlic extract rescues ethephon-induced kidney damage.Jan 31, 2021

Pubmed Data : Environ Sci Pollut Res Int. 2021 Feb ;28(6):6818-6829. Epub 2020 Oct 3. PMID: 33011947
Article Published Date : Jan 31, 2021
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Inflammation, Kidney Damage: Chemically-Induced, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Nrf2 activation
Additional Keywords : Plant Extracts
[+]

Aged garlic extract supplementation could be used to reverse the hepatic injury following ethephon exposure through its antioxidant capacity.Dec 20, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 Dec 21. Epub 2019 Dec 21. PMID: 31865585
Article Published Date : Dec 20, 2019
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Aged garlic extract suppressed the proliferative activity in adenoma and adenocarcinoma lesions, but showed no effect on normal colon mucosa.Feb 28, 2015

Pubmed Data : Oncol Rep. 2015 Mar ;33(3):1131-40. Epub 2014 Dec 30. PMID: 25573280
Article Published Date : Feb 28, 2015
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Colon Cancer, Colon Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Chemopreventive, NF-kappaB Inhibitor
Additional Keywords : Selective Antiproliferation
[+]

Aged garlic extract suppresses the development of atherosclerosis in apolipoprotein E-knockout mice.Jan 31, 2016

Pubmed Data : J Nutr. 2016 Feb ;146(2):460S-3S. Epub 2016 Jan 13. PMID: 26764329
Article Published Date : Jan 31, 2016
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Atherosclerosis, Coronary Artery Disease
Pharmacological Actions : Anti-atherogenic
[+]

Aged garlic extract was able to reduce titanium dioxide toxicity in male rats. Aug 21, 2016

Pubmed Data : Andrologia. 2016 Aug 22. Epub 2016 Aug 22. PMID: 27546106
Article Published Date : Aug 21, 2016
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Problem Substances : Titanium Nanoparticles
[+]

An extract of aged black garlic significantly suppressed IgE-induced anaphylaxis in a (PCA) model.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Food. 2014 Jan ;17(1):92-102. PMID: 24456359
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Garlic: Aged, Polyphenols
Diseases : Allergies, Anaphylaxis, IgE-Mediated Hypersensitivity
Pharmacological Actions : Anti-Allergic Agents, Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Anti-inflammatory and vasorelaxant effects induced by an aqueous aged black garlic extract supplemented with vitamins D, C, and B12 on cardiovascular system.Apr 05, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2023 Apr 6 ;12(7). Epub 2023 Apr 6. PMID: 37048379
Article Published Date : Apr 05, 2023
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged, Vitamin B12, Vitamin C, Vitamin D
Diseases : Cardiovascular Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Cyclooxygenase 2 Inhibitors, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vasoprotective
[+]

Effect of combined extracts of aged garlic, ginger, and chili peppers on cognitive performance and brain antioxidant markers.Feb 10, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Anim. 2020 Feb 11. Epub 2020 Feb 11. PMID: 32051390
Article Published Date : Feb 10, 2020
Study Type : Animal Study
Additional Links
Substances : Chili pepper, Garlic: Aged, Ginger
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Regulation of immune response by S-1-propenylcysteine through autophagy-mediated protein degradation.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2020 Feb ;19(2):1570-1573. Epub 2019 Dec 27. PMID: 32010341
Article Published Date : Jan 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Garlic: Aged
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
[+]

S-allyl cysteine may be useful for the prevention or treatment of pulmonary fibrosis.Mar 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2017 Mar 29 ;22(4). Epub 2017 Mar 29. PMID: 28353632
Article Published Date : Mar 28, 2017
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic
[+]

SAC significantly resolved carbon tetrachloride induced liver fibrosis with a decrease in the profibrogenic cytokine TGF-β as well as the antioxidative properties of SAC.Apr 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Biochem Nutr. 2015 May ;56(3):179-85. Epub 2015 Mar 28. PMID: 26060347
Article Published Date : Apr 30, 2015
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Chemically-Induced Liver Damage, Liver Fibrosis
Pharmacological Actions : Antioxidants, Hepatoprotective
Additional Keywords : Plant Extracts
[+]

Swimming exercise supplemented with garlic extract not only improves antioxidant capacity but also declines oxidative damages and apoptosis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Interv Aging. 2020 ;15:1409-1418. Epub 2020 Aug 18. PMID: 32884250
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Kidney Damage, Liver Damage, Oxidative Stress
Therapeutic Actions : Exercise: Swimming
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hepatoprotective, Renoprotective
[+]

Synergistic effects of black ginseng and aged garlic extracts for the amelioration of nonalcoholic fatty liver disease.May 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2021 Jun ;9(6):3091-3099. Epub 2021 May 4. PMID: 34136174
Article Published Date : May 31, 2021
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged, Ginseng
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substance Synergy
[+]

The results support AGE antioxidant, anti-inflammatory, and antimicrobial potency reflected by the healing of the gastric tissue damage induced by indomethacin.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2014 ;2014:759642. Epub 2014 Apr 30. PMID: 24876878
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Garlic: Aged
Diseases : Drug-Induced Toxicity: Gastrointestinal, Drug-Induced Toxicity: Indomethacin, Gastrointestinal Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antimicrobial, Antioxidants
Additional Keywords : Plant Extracts
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

AGE inhibits platelet aggregation by increasing cyclic nucleotides and inhibiting fibrinogen binding and platelet shape change.Jan 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr. 2016 Feb ;146(2):410S-5S. Epub 2016 Jan 13. PMID: 26764324
Article Published Date : Jan 31, 2016
Study Type : Review
Additional Links
Substances : Garlic: Aged
Diseases : Cardiovascular Diseases
Pharmacological Actions : Platelet Aggregation Inhibitors
Additional Keywords : Risk Reduction
[+]

Aged black garlic extract inhibited the growth and induced apoptosis in HT29 cells through the inhibition of the PI3K/Akt pathwayFeb 28, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Rep. 2014 Mar ;2(2):250-254. Epub 2014 Jan 20. PMID: 24649105
Article Published Date : Feb 28, 2014
Study Type : In Vitro Study
Additional Links
Substances : Garlic: Aged
Diseases : Colon Cancer, Colon Cancer: Prevention
Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive, Chemotherapeutic
[+]

Aged black garlic extract inhibits the growth of estrogen receptor-positive breast cancer cells.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2023 ;18(6):e0286454. Epub 2023 Jun 23. PMID: 37352173
Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Garlic: Aged
Diseases : Breast Cancer
Pharmacological Actions : Antioxidants, Antiproliferative , Apoptotic, Bcl-2 protein down-regulation
Additional Keywords : Plant Extracts
[+]

Aged garlic extract and its constituent, S-allyl-L-cysteine, induce the apoptosis of neuroblastoma cancer cellsJan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2020 Feb ;19(2):1511-1521. Epub 2019 Dec 27. PMID: 32010332
Article Published Date : Jan 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Garlic: Aged
Diseases : Neuroblastoma
Pharmacological Actions : Apoptotic
[+]

Aged garlic extract as a potential prophylactic to reduce the progression of endometriosis and associated pain burden.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pain Res (Lausanne). 2022 ;3:1057830. Epub 2022 Nov 17. PMID: 36466216
Article Published Date : Dec 31, 2021
Study Type : Review
Additional Links
Substances : Garlic: Aged
Diseases : Endometriosis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Prophylactic Agents
[+]

Aged red garlic extract may enhance anti-inflammatory effects by controlling other anti-inflammatory signals as well as regulation of NF-κB.Mar 31, 2015

Pubmed Data : J Med Food. 2015 Apr ;18(4):439-45. Epub 2015 Jan 13. PMID: 25584924
Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Garlic: Aged
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Heme oxygenase-1 up-regulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor
[+]

Benefits of aged garlic extract on Alzheimer's disease: Possible mechanisms of action.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2020 Feb ;19(2):1560-1564. Epub 2019 Dec 27. PMID: 32010339
Article Published Date : Jan 31, 2020
Study Type : Review
Additional Links
Substances : Garlic: Aged
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Dietary supplements and nutraceuticals could help with hypertension.Mar 18, 2015

Pubmed Data : High Blood Press Cardiovasc Prev. 2015 Mar 19. Epub 2015 Mar 19. PMID: 25788027
Article Published Date : Mar 18, 2015
Study Type : Review
Additional Links
Substances : Arginine, Beet, Cocoa, Coenzyme Q10, Garlic: Aged, Melatonin, Potassium, Vitamin C
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents
[+]

HEABG reduces leukemic cell growth by inducing caspase-dependent apoptosis through both intrinsic and extrinsic pathways.Mar 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2014 Apr ;8(2):132-7. Epub 2014 Mar 28. PMID: 24741395
Article Published Date : Mar 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Garlic: Aged
Diseases : Leukemia
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-8 activation
[+]

Mechanisms underlying the attenuation of chronic inflammatory diseases by aged garlic extract: Involvement of the activation of AMP-activated protein kinase.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2020 Feb ;19(2):1462-1467. Epub 2019 Dec 27. PMID: 32010323
Article Published Date : Jan 31, 2020
Study Type : Review
Additional Links
Substances : Garlic: Aged
Diseases : Atherosclerosis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Potential benefits of garlic and other dietary supplements for the management of hypertension.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2020 Feb ;19(2):1479-1484. Epub 2019 Dec 27. PMID: 32010326
Article Published Date : Jan 31, 2020
Study Type : Review
Additional Links
Substances : Coenzyme Q10, Fish Oil, Garlic: Aged, Probiotics
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents
[+]

Sulfur-containing amino acids in aged garlic extract inhibit inflammation in human gingival epithelial cells.Feb 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Rep. 2020 Mar ;12(3):99-108. Epub 2019 Dec 30. PMID: 32042418
Article Published Date : Feb 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Garlic: Aged
Diseases : Atherosclerosis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

These results support the use of aged garlic extract and S-allylcysteine as a therapeutic alternative for hypoxic conditions.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Res. 2016 ;49(1):7. Epub 2016 Feb 1. PMID: 26830333
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Garlic: Aged
Diseases : Hypoxia
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
Problem Substances : Cobalt
[+]

This experimental data provides information for the molecular targets of AGE and its components to mitigate neurodegeneration and neuroinflammation.Aug 31, 2016

Pubmed Data : Neuromolecular Med. 2016 Sep ;18(3):474-82. Epub 2016 Jun 4. PMID: 27263111
Article Published Date : Aug 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Garlic: Aged
Diseases : Alzheimer's Disease, Brain Inflammation , Cerebral Ischemia, Huntington Disease, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, NF-E2-Related Factor-2 (Nrf2) Modulator
Additional Keywords : Plant Extracts
[+]

This study advances the antimicrobial potential of AGE to inhibit drug-resistant C. albicans and bacterial-associated polymicrobial biofilms.Apr 24, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antibiotics (Basel). 2022 Apr 25 ;11(5). Epub 2022 Apr 25. PMID: 35625217
Article Published Date : Apr 24, 2022
Study Type : In Vitro Study
Additional Links
Substances : Garlic: Aged
Diseases : Candida Albicans, Escherichia coli Infections, Infection: Antibiotic Resistant
Pharmacological Actions : Antimicrobial
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation

Copyright: marchsirawit / 123RF Stock Photo

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