Geum japonicum

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19 Diseases Researched for Geum japonicum
NameACCKFocus
Myocardial Infarction46Locked
Atherosclerosis23Locked
Cerebral Ischemia12Locked
Coronary Artery Disease12Locked
Cytomegalovirus Infections12Locked
Endothelial Dysfunction12Locked
HIV Infections22Locked
HSV-112Locked
Herpes Simplex Virus Type 112Locked
Herpes Simplex Virus Type 212Locked
High Fat Diet12Locked
Hypertension12Locked
Ischemia: Myocardial12Locked
Nonalcoholic fatty liver disease (NAFLD)12Locked
Heart Disease: Ischemic11Locked
Ischemia11Locked
Ischemic Heart Disease11Locked
Melanoma11Locked
Heart Attack10Locked
20 Pharmacological Actions Researched for Geum japonicum
NameACCKFocus
Antiviral Agents47Locked
Cardioprotective24Locked
Anti-Apoptotic12Locked
Antihypertensive Agents12Locked
Antioxidants12Locked
Enzyme Inhibitors12Locked
Hypolipidemic12Locked
Neuroprotective Agents12Locked
Nrf2 activation12Locked
Vasodilator Agents12Locked
Angiogenesis Inducing Agents11Locked
Angiogenesis Inhibitors11Locked
Anti-HIV Agents11Locked
Anti-metastatic11Locked
Antiproliferative 11Locked
HIV Protease Inhibitors11Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor11Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor11Locked
Neocardiogenic 21Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor11Locked

View the Evidence:
16 Abstracts with Geum japonicum Research

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Extracts of Geum japonicum may have potential use as new anti-hypertensive agents for lowering arterial blood pressure in hypertensive patients.Jan 02, 2007

Pubmed Data : J Ethnopharmacol. 2007 Jan 3 ;109(1):128-33. Epub 2006 Jul 21. PMID: 16939706
Article Published Date : Jan 02, 2007
Study Type : Animal Study
Additional Links
Substances : Geum japonicum , Tannic Acid
Diseases : Endothelial Dysfunction, Hypertension
Pharmacological Actions : Antihypertensive Agents, Enzyme Inhibitors, Vasodilator Agents
Additional Keywords : Plant Extracts
[+]

Geum japonicum and Clove contains the compound eugeniin which inhibit HSV-1 and HSV-2 virus replication. Feb 01, 1998

Pubmed Data : J Pharmacol Exp Ther. 1998 Feb;284(2):728-35. PMID: 9454821
Article Published Date : Feb 01, 1998
Study Type : Animal Study
Additional Links
Substances : Clove, Geum japonicum
Diseases : Herpes Simplex Virus Type 1, Herpes Simplex Virus Type 2
Pharmacological Actions : Antiviral Agents
Additional Keywords : Plant Extracts
[+]

Geum japonicum, Rhus javanica, Clove, and Terminalia chebula work synergistically with acyclovir against herpes simplex virus type 1 infection in vitro and in vivo. May 01, 1995

Pubmed Data : Antiviral Res. 1995 May;27(1-2):19-37. PMID: 7486956
Article Published Date : May 01, 1995
Study Type : Animal Study
Additional Links
Substances : Clove, Geum japonicum , Rhus javanica, Terminalia
Diseases : HSV-1
Pharmacological Actions : Antiviral Agents
[+]

Geum japonicum, Syzygium aromaticum (Clove), and Terminalia chebula inhibit Cytomegalovirus infection.Jan 01, 1998

Pubmed Data : Nippon Rinsho. 1998 Jan;56(1):156-60. PMID: 9465682
Article Published Date : Jan 01, 1998
Study Type : Animal Study
Additional Links
Substances : Clove, Geum japonicum , Sumac, Terminalia
Diseases : Cytomegalovirus Infections
Pharmacological Actions : Antiviral Agents
Additional Keywords : Drug: Ganciclovir, Superiority of Natural Substances versus Drugs
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Geum joponicum extracts may provide a novel therapeutic method for effective treatment of chronic coronary heart disease.Feb 03, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2014 Feb 4 ;4:3962. Epub 2014 Feb 4. PMID: 24492623
Article Published Date : Feb 03, 2014
Study Type : Animal Study
Additional Links
Substances : Geum japonicum
Diseases : Atherosclerosis, Coronary Artery Disease, Myocardial Infarction
Pharmacological Actions : Cardioprotective
Additional Keywords : Atherosclerosis, Cardioprotective, Coronary Artery Disease, Geum japonicum, Myocardial Infarction, myocardial regeneration, Plant Extracts
[+]

Myocardial regeneration and repair of infarcted heart by a new composition isolated from Geum japonicumApr 30, 2011

Pubmed Data : Zhonghua Xin Xue Guan Bing Za Zhi. 2011 May ;39(5):414-9. PMID: 21781595
Article Published Date : Apr 30, 2011
Study Type : Animal Study
Additional Links
Substances : Geum japonicum
Diseases : Myocardial Infarction
Pharmacological Actions : Cardioprotective
Additional Keywords : Cardioprotective, Geum japonicum, Myocardial Infarction, myocardial regeneration
[+]

Niga-ichigoside F1 ameliorates high-fat diet-induced hepatic steatosis in male mice by Nrf2 activation.Feb 20, 2018

Pubmed Data : Food Funct. 2018 Feb 21 ;9(2):906-916. PMID: 29309075
Article Published Date : Feb 20, 2018
Study Type : Animal Study
Additional Links
Substances : Geum japonicum , Herb Bennet
Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Antioxidants, Hypolipidemic, Nrf2 activation
Additional Keywords : Plant Extracts
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Repair of infarcted myocardium by an extract of Geum japonicum with dual effects on angiogenesis and myogenesis.Aug 01, 2006

Pubmed Data : Clin Chem. 2006 Aug;52(8):1460-8. Epub 2006 Jun 22. PMID: 16873297
Article Published Date : Aug 01, 2006
Study Type : Animal Study
Additional Links
Substances : Geum japonicum
Diseases : Ischemia: Myocardial, Myocardial Infarction
[+]

The antiapoptosis effect of Geum japonicum Chinese extracts on cerebral ischemia reperfusion injury.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:7290170. Epub 2018 Nov 14. PMID: 30538763
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Geum japonicum , Herb Bennet
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

3,4,5-trihydroxybenzaldehyde from Geum japonicum has dual inhibitory effect on matrix metalloproteinase 9; inhibition of gelatinoytic activity.Sep 30, 2008

Pubmed Data : J Cell Biochem. 2008 Oct 1 ;105(2):524-33. PMID: 18773430
Article Published Date : Sep 30, 2008
Study Type : In Vitro Study
Additional Links
Substances : Geum japonicum , Herb Bennet
Diseases : Atherosclerosis
Pharmacological Actions : Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

A compound found within Geum japonicum may contribute to the process of myofiber regeneration and muscle repair. Jan 01, 2006

Pubmed Data : Int J Biochem Cell Biol. 2006;38(7):1123-33. Epub 2006 Jan 6. PMID: 16431151
Article Published Date : Jan 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Geum japonicum
Diseases : Heart Disease: Ischemic, Ischemic Heart Disease
Pharmacological Actions : Neocardiogenic
Additional Keywords : myocardial regeneration
[+]

Geum japonicum contains a compound with anti-HIV activity. Sep 01, 2000

Pubmed Data : Chem Pharm Bull (Tokyo). 2000 Sep;48(9):1367-9. PMID: 10993241
Article Published Date : Sep 01, 2000
Study Type : In Vitro Study
Additional Links
Substances : Geum japonicum
Diseases : HIV Infections
Pharmacological Actions : Anti-HIV Agents, HIV Protease Inhibitors
[+]

Geum japonicum contains compounds which exhibit potent anti-HIV protease activity. Jul 01, 1996

Pubmed Data : J Nat Prod. 1996 Jul;59(7):643-5. PMID: 8759159
Article Published Date : Jul 01, 1996
Study Type : In Vitro Study
Additional Links
Substances : Geum japonicum
Diseases : HIV Infections
Pharmacological Actions : Antiviral Agents
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Geum japonicum Thunberg extracts inhibits tumor metastatic and angiogenic potential.May 31, 2008

Pubmed Data : Oncol Rep. 2008 Jun ;19(6):1399-403. PMID: 18497943
Article Published Date : May 31, 2008
Study Type : In Vitro Study
Additional Links
Substances : Geum japonicum
Diseases : Melanoma
Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Antiproliferative
Additional Keywords : Plant Extracts
[+]

The dual actions of angiogenesis and anti-apoptosis induced by an isolated fraction from Geum japonicum repair muscle ischemia.Feb 28, 2007

Pubmed Data : Arch Biochem Biophys. 2007 Mar 1 ;459(1):91-7. Epub 2006 Nov 7. PMID: 17188640
Article Published Date : Feb 28, 2007
Study Type : In Vitro Study
Additional Links
Substances : Geum japonicum
Diseases : Ischemia
Pharmacological Actions : Angiogenesis Inducing Agents
Additional Keywords : Muscle Regeneration, Plant Extracts
[+]

Geum japonicum stimulates myocardial regeneration in an acute myocardial infaraction animal model. Jan 01, 2009

Pubmed Data : PLoS One. 2009;4(2):e4461. Epub 2009 Feb 14. PMID: 19221596
Article Published Date : Jan 01, 2009
Additional Links
Substances : Geum japonicum
Diseases : Heart Attack, Myocardial Infarction
Pharmacological Actions : Neocardiogenic
Additional Keywords : myocardial regeneration

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