Ginger

Name	AC	CK
Diabetes Mellitus: Type 2	16	86
Osteoarthritis: Knee	9	81
Inflammation	24	65
Oxidative Stress	17	56
Chemotherapy-Induced Nausea	7	52
Dysmenorrhea	4	50
Nausea: Chemotherapy-Induced	4	50
Nausea: Post-Operative	4	50
Dyspepsia	5	41
Obesity	13	40
Insulin Resistance	7	38
Chronic Pain	3	31
Diabetes Mellitus: Type 2: Prevention	3	30
Diabetes Mellitus: Type 1	4	24
Hyperlipidemia	8	24
Breast Cancer	11	23
Cancers: All	11	21
Muscle Soreness	3	21
Atherosclerosis	1	20
Diabetes: Glycation/A1C	2	20
High Cholesterol	2	20
Nausea	2	20
Periodontitis	2	20
Rheumatoid Arthritis	2	20
Metabolic Syndrome X	5	17
Chemotherapy-Induced Toxicity: Cisplatin	8	15
Colon Cancer	8	15
Chemically-Induced Liver Damage	7	14
Diabetic Complications	8	14
Colorectal Cancer	4	13
Chemotherapy and Radiation Toxicity	3	12
Cognitive Decline/Dysfunction	2	12
Diabetes Mellitus: Type 1: Prevention	2	12
Helicobacter Pylori Infection	2	12
Hypercholesterolemia	2	12
Alopecia	2	11
Alzheimer's Disease	8	11
Lipopolysaccharide-Induced Toxicity	7	11
Menopausal Syndrome	2	11
Alcohol Toxicity	5	10
Anxiety: Preoperative	1	10
Bleeding: Excessive	1	10
Breast Milk: Inadequate/Poor Quality	1	10
C-Reactive Protein	1	10
C-Reactive Protein (CRP)	1	10
Cachexia: Cancer	1	10
Cardiovascular Disease: Prevention	1	10
Cesarean Section	1	10
Chemotherapy-Induced Toxicity	1	10
Cholesterol: High	1	10
Delayed Gastric Emptying	1	10
Fatigue: Cancer-Associated	1	10
Gastroparesis	1	10
Hemodialysis	1	10
Hyperglycemia	1	10
Menorrhagia	1	10
Migraines	1	10
Morning Sickness	1	10
Motion Sickness	1	10
Muscle Damage	1	10
Muscle Soreness: Exercise-Induced	1	10
Myelodysplastic Syndrome	1	10
Nausea: Pregnancy-Associated	1	10
Nausea: Sea-Sickness	1	10
Neurogenic Bladder	1	10
Overweight	1	10
Pneumonia	1	10
Postoperative Recovery	1	10
Prediabetes	1	10
Premenopausal Disorders	1	10
Quality of Life: Poor	1	10
Respiratory Distress Syndrome	1	10
Stroke: PostStroke Urinary Disorders	1	10
Triglycerides: Elevated	1	10
Tuberculosis	1	10
Uterine Bleeding	1	10
Vertigo	1	10
Weight Probems: Appetite	1	10
Brain Inflammation	5	9
Hypertension	5	9
Kidney Damage: Chemically-Induced	5	9
Diabetes: Oxidative Stress	4	8
Myocardial Infarction	4	8
Pancreatic Cancer	3	8
Prostate Cancer	6	8
Sepsis	2	7
Brain Damage	3	6
Carcinoma: Non-Small-Cell Lung	2	6
Diabetic Nephropathy	3	6
Lipid Peroxidation	3	6
Liver Cancer: Prevention	3	6
Neurodegenerative Diseases	4	6
Parabens-Associated Toxicity	4	6
Arsenic Poisoning	3	5
Cancers	1	5
Escherichia coli Infections	4	5
Gastric Ulcer	4	5
Radiation Induced Illness	3	5
Respiratory Syncytial Virus Infections	1	5
Staphylococcus aureus infection	5	5
Arthritis: Rheumatoid	2	4
Cadmium Poisoning	2	4
Chemotherapy-Induced Toxicity: Doxorubicin	2	4
Colitis	2	4
DNA damage	3	4
Diabetes: Cardiovascular Illness	2	4
Diabetes: Kidney Function	2	4
Endotoxemia	2	4
Fructose-Induced Toxicity	2	4
Giardiasis	2	4
High Fat Diet	2	4
High Fructose Diet	2	4
Irritable Bowel Syndrome	2	4
Lung Cancer	3	4
Multiple Sclerosis	3	4
Neuropathic Pain	2	4
Nonalcoholic fatty liver disease (NAFLD)	2	4
Pesticide Toxicity	2	4
Pseudomonas aeruginosa	4	4
Testicular Injury: Chemical/Metal Induced	2	4
Bisphenol Toxicity	2	3
Bronchopulmonary Dysplasia	1	3
Cancer Metastasis	3	3
Cancers: Drug Resistant	3	3
Cerebral Ischemia	2	3
Coronavirus Infection	3	3
Diarrhea	2	3
Dog Diseases	2	3
Gastric Cancer	2	3
Gastroesophageal Reflux	2	3
Liver Cancer	3	3
Pets: Heartworm	2	3
ALT: Elevated	1	2
AST: Elevated	1	2
Acetaminophen (Tylenol) Toxicity	1	2
Acid Reflux	1	2
Aging	2	2
Alcoholic Liver Disease	1	2
Allergic Rhinitis	1	2
Allergic Rhinitis: Prevention	1	2
Aluminum Toxicity	1	2
Antibiotic Toxicity	1	2
Bacterial Infections: Resistance/Biofilm Formation	2	2
Brain: Microglial Activation	1	2
Bromobenzene Toxicity	1	2
Cardiac Hypertrophy	1	2
Cardiomyopathy	1	2
Cardiovascular Diseases	2	2
Cervical Cancer	2	2
Chemical Exposure	1	2
Chemotherapy-Induced Toxicity: Cyclophosphamide	1	2
Cholesterol: LDL/HDL ratio	1	2
Cytomegalovirus Infections	1	2
Dementia	2	2
Depression	1	2
Diabetes: Cognitive Dysfunction	1	2
Diabetic Glomerular Hypertrophy	1	2
Diabetic Neuropathy	1	2
Dysbiosis	1	2
Encephalomyelitis	1	2
Endocrine Imbalances	1	2
Enterococcus Infections	2	2
Esophageal Cancer	1	2
Excitotoxicity	1	2
Fat Malabsorption	1	2
Fibrosis	1	2
Gout	1	2
HIV Infections	1	2
HSV-1	1	2
Hepatic Steatosis	1	2
Hyperinsulinism	1	2
Hyperuricemia	1	2
Indigestion: Fats	1	2
Infertility: Female	1	2
Inflammatory Bowel Diseases	1	2
Influenza	1	2
Kidney Damage	1	2
Kidney Failure	1	2
Kidney Failure: Acute	1	2
Kidney Failure: Chronic	1	2
Lead Poisoning	1	2
Leptin: Elevated Levels	1	2
Liver Damage	1	2
Liver Damage: Aflatoxin-Induced	1	2
Liver Fibrosis	1	2
Liver Steatosis	1	2
Liver Stress: Fructose-Induced	1	2
Lung Injury: Acute	1	2
Malabsorption Syndrome	1	2
Memory Disorders	1	2
Mercury Poisoning	1	2
Microvilli atrophy	1	2
Morphine Tolerance/Dependence	1	2
Myocardial Fibrosis	1	2
Necrotising enterocolitis	1	2
Osteoarthritis	1	2
Pain	1	2
Parkinson's Disease	2	2
Pyelonephritis	1	2
Schistosomiasis	1	2
Steatorrhea	1	2
Trigeminal Neuralgia	1	2
Uremia	1	2
Acute lymphoblastic leukemia (ALL)	1	1
Advanced Glycation End products (AGE)	1	1
Advanced Glycation Endproduct (AGE) Formation	1	1
Allergic Airway Diseases	1	1
Allergies	1	1
Asthma	1	1
Avian Influenza	1	1
Bacillus Cereus infection	1	1
Bone Diseases	1	1
Breast Cancer: Chemically-Induced	1	1
Breast Cancer: Triple Negative	1	1
Candida Albicans	1	1
Candida Glabrata	1	1
Candidiasis: Vulvovaginal	1	1
Central Nervous System Diseases	1	1
Cholesterol: Oxidation	1	1
Chronic Disease	1	1
Colic	1	1
Echinococcosis	1	1
Endometriosis	1	1
Epstein-Barr Virus Infections	1	1
Fatty Liver	1	1
Foodborne Pathogens: Prevention/Food Preservation	1	1
Gastrointestinal Cancer	1	1
Gastrointestinal Inflammation	1	1
Glioblastoma	1	1
Haemophilus influenzae	1	1
Hair Loss	1	1
Hydatidosis	1	1
Hypersensitivity: Respiratory	1	1
Hypoglycemia	1	1
Infection: Antibiotic Resistant	1	1
Listeria Infections	1	1
Liver Disease: Oxidative Stress	1	1
Lymphoma: Dalton's	1	1
Malignant Melanoma	1	1
Melanoma	1	1
Micrococcus luteus infections	1	1
Mycobacterium Infections	1	1
Oral Cancer	1	1
Osteoporosis	1	1
Parasitic Intestinal Diseases	1	1
Polycystic Ovary Syndrome	1	1
Premenstrual syndrome	1	1
Prostatic Hyperplasia	1	1
Rhabdomyosarcoma	1	1
Rhinovirus Infection	1	1
Salmonella Infections	1	1
Skin Cancer: Squamous Cell	1	1
Squamous cell carcinoma	1	1
Streptococcus pyogenes	1	1
Thrombosis	1	1
Toxoplasma gondii Infection	1	1
Tumors	1	1
Ultraviolet Radiation Induced Damage	1	1
Upper Respiratory Infections	1	1

Name	AC	CK
Anti-Inflammatory Agents	70	182
Antioxidants	59	142
Analgesics	15	129
Tumor Necrosis Factor (TNF) Alpha Inhibitor	30	61
Gastrointestinal Agents	10	49
Hypoglycemic Agents	13	48
Insulin Sensitizers	7	46
Hypolipidemic	14	43
Antiemetics	3	40
Hepatoprotective	20	39
Chemotherapeutic	9	37
Apoptotic	27	35
Interleukin-6 Downregulation	18	34
NF-kappaB Inhibitor	15	34
Neuroprotective Agents	20	32
Antiproliferative	21	27
Interleukin-1 beta downregulation	14	26
Renoprotective	13	26
Antineoplastic Agents	5	25
Anti-Bacterial Agents	13	23
Aldose reductase inhibitor	2	20
Immunomodulatory	8	19
Cardioprotective	8	16
Chemoprotective Agents	9	16
Chemopreventive	12	15
Malondialdehyde Down-regulation	3	15
Nitric Oxide Inhibitor	3	14
Postaglandin PGE2 downregulation	3	13
Anti-Apoptotic	6	12
Gastroprotective	2	12
Radioprotective	8	12
Anti-Cachexic Agents	1	10
Anticholesteremic Agents	1	10
Antioxidant Effects	1	10
Antiviral Agents	5	10
Galactogogue	1	10
Thermogenic	1	10
Vasopressin Inhibitor	1	10
Anti-metastatic	9	9
Cyclooxygenase 2 Inhibitors	5	9
Anticarcinogenic Agents	6	8
Bcl-2 protein down-regulation	5	7
Cell cycle arrest	5	7
Cytoprotective	2	7
Acetylcholinesterase Inhibitor	4	6
Antiparasitic Agents	5	6
Interleukin-10 downregulation	3	6
Superoxide Dismutase Up-regulation	3	6
Tumor Suppressor Protein p53 Upregulation	2	6
Wnt/β-catenin signaling pathway modulation	2	6
Caspase-3 Activation	1	5
Chemosensitizer	4	5
Immunostimulatory	3	5
Matrix metalloproteinase-9 (MMP-9) inhibitor	4	5
MicroRNA modulator	3	5
Neurogenesis	1	5
Nrf2 activation	3	5
P21 Activation	1	5
Antihypertensive Agents	2	4
Antimicrobial	3	4
Antiprotozoal Agents	2	4
Glutathione Upregulation	2	4
Insulin-releasing	2	4
Malonaldehyde (MDA) Down-Regulation	2	4
Matrix metalloproteinase-2 (MMP-2) inhibitor	3	4
Spermatogenic	2	4
Autophagy Up-regulation	2	3
Adenosine deaminase inhibitor	1	2
Anti-Allergic Agents	1	2
Anti-Angiogenic	1	2
Anti-Fibrotic	1	2
Anti-Glycation Agents	2	2
Anti-Ulcer Agents	1	2
Antidepressive Agents	1	2
Antidiarrheals	1	2
Antigiardial agents	1	2
Bax/Bcl2 Ratio: Decrease	1	2
Calcium Channel Blockers	1	2
Detoxifier	1	2
Enzyme Inhibitors	2	2
Enzyme Inhibitors: Pancreatic Lipase	1	2
Fertility Agents: Female	1	2
Heme oxygenase-1 inducer	1	2
Heme oxygenase-1 up-regulation	1	2
Interleukin-2 Downregulation	1	2
Leptin Down-Regulation	1	2
Osteoprotective	2	2
Prophylactic Agents	1	2
Prostaglandin Antagonists	1	2
Proton Pump Inhibitor	1	2
Transforming growth factor beta (TGF-β) inhibitor	1	2
Vascular Endothelial Growth Factor Inhibitors	1	2
Vasodilator Agents	1	2
angiogenesis	1	2
Alpha-glucosidase inhibitor	1	1
Angiogenesis Inhibitors	1	1
Anti-Platelet	1	1
Anti-thrombotic	1	1
Antifungal Agents	1	1
Antispasmodic	1	1
Autophagy Inhibitors	1	1
Food Preservatives	1	1
Genoprotective	1	1
Histone deacetylase inhibitor	1	1
Interleukin-4 downregulation	1	1
Interleukin-5 downregulation	1	1
Interleukin-8 downregulation	1	1
Paraptosis	1	1
Phase II Detoxification Enzyme Inducer	1	1
Photoprotective	1	1
Quorum Sensing Inhibition	1	1
Regenerative	1	1
Scolicidal	1	1
Survivin Down-Regulation	1	1
TRAIL sensitizer	1	1
Telomerase Inhibitor	1	1
interleukin-13 down-regulation	1	1
β-secretase Inhibitor	1	1

[+]

Collectively these RCTs provide suggestive evidence for the effectiveness of 750-2000 mg ginger powder during the first 3-4 days of menstrual cycle for primary dysmenorrhea.Jul 13, 2015

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Pubmed Data : Pain Med. 2015 Jul 14. Epub 2015 Jul 14. PMID: 26177393

Article Published Date : Jul 13, 2015

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Pubmed Data : Phytomedicine. 2018 Apr 1 ;43:28-36. Epub 2018 Mar 19. PMID: 29747751

Article Published Date : Mar 31, 2018

Study Type : Meta Analysis

Additional Links

Substances : Ginger

Diseases : Atherosclerosis

[+]

Zingiberaceae extracts are clinically effective hypoalgesic agents and the available data show a better safety profile than non steroidal anti inflammatory drugs.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr J. 2015 ;14:50. Epub 2015 May 14. PMID: 25972154

Article Published Date : Dec 31, 2014

Aromatherapy massage performed in elderly patients with knee osteoarthritis reduced pain and improved functional status and quality of life.May 29, 2019

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Pubmed Data : Jpn J Nurs Sci. 2019 May 30. Epub 2019 May 30. PMID: 31144450

Article Published Date : May 29, 2019

Study Type : Human Study

Additional Links

Substances : Ginger, Rosemary

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Aromatherapy

Pharmacological Actions : Analgesics

Additional Keywords : Essential Oils

[+]

Aromatherapy with light Thai massage can be beneficial for the immune systems of cancer patients who are undergoing chemotherapy.Dec 31, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Cancer Manag Res. 2017 ;9:11-18. Epub 2017 Jan 31. PMID: 28203106

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Substances : Ginger

Diseases : Chemotherapy and Radiation Toxicity

Pharmacological Actions : Antioxidants, Chemotherapeutic

[+]

Effect of treatment with ginger on the severity of premenstrual syndrome symptoms.Dec 31, 2013

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Pubmed Data : ISRN Obstet Gynecol. 2014 ;2014:792708. Epub 2014 May 4. PMID: 24944825

Article Published Date : Dec 31, 2013

Study Type : Human Study

Additional Links

Substances : Ginger

Diseases : Premenopausal Disorders

[+]

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Gene. 2019 May 25 ;698:179-185. Epub 2019 Mar 4. PMID: 30844477

Pubmed Data : Saudi Med J. 2008 Sep;29(9):1280-4. PMID: 18813412

Article Published Date : Sep 01, 2008

Study Type : Human Study

Additional Links

Substances : Ginger

Diseases : Cholesterol: High, High Cholesterol, Hypercholesterolemia, Hyperlipidemia

[+]

Ginger has a therapeutic effect on motion sickness. Jan 01, 2007

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Pubmed Data : Nutr Cancer. 2007;58(1):60-5. PMID: 12576305

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Tradit Complement Med. 2016 Jul ;6(3):199-203. Epub 2015 Jan 28. PMID: 27419081

[+]

Ginger supplementation is an effective treatment for type 2 diabetes. Feb 03, 2014

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Pubmed Data : Int J Food Sci Nutr. 2014 Feb 4. Epub 2014 Feb 4. PMID: 24490949

Article Published Date : Feb 03, 2014

Study Type : Human Study

Additional Links

Substances : Ginger

Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 1: Prevention, Diabetes Mellitus: Type 2, Diabetes Mellitus: Type 2: Prevention

Pharmacological Actions : Aldose reductase inhibitor

[+]

Ginger supplementation may be used to accelerate recovery of muscle strength following intense exerciseMay 31, 2015

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Pubmed Data : Phytother Res. 2015 Jun ;29(6):887-93. Epub 2015 Mar 18. PMID: 25787877

Protein and ginger may have therapeutic value in the treatment of chemotherapy-induced delayed nausea.Jun 01, 2008

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Pubmed Data : J Altern Complement Med. 2008 Jun;14(5):545-51. PMID: 18537470

Article Published Date : Jun 01, 2008

Study Type : Human Study

Additional Links

Substances : Ginger, Protein Supplement

Diseases : Chemotherapy-Induced Nausea, Nausea

Pharmacological Actions : Antiemetics

[+]

Self-knee massage with ginger oil in patients with osteoarthritis.Oct 31, 2017

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Pubmed Data : Res Theory Nurs Pract. 2017 Nov 1 ;31(4):379-392. PMID: 29137696

Article Published Date : Oct 31, 2017

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Pubmed Data : BMC Complement Med Ther. 2020 Apr 20 ;20(1):119. Epub 2020 Apr 20. PMID: 32312261

Article Published Date : Apr 19, 2020

Study Type : Human Study

Additional Links

Substances : Ginger

Diseases : Allergic Rhinitis

Pharmacological Actions : Anti-Allergic Agents

Additional Keywords : Natural Substances Versus Drugs, Plant Extracts, Superiority of Natural Substances versus Drugs

[+]

The herbal remedies examined had significantly beneficial effects on cholesterol in T2D patients.Aug 31, 2014

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Pubmed Data : Rev Diabet Stud. 2014 Fall-Winter;11(3-4):258-66. Epub 2015 Feb 10. PMID: 26177486

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Eur Rev Med Pharmacol Sci. 2016 Dec ;20(24):5198-5204. PMID: 28051248

Article Published Date : Nov 30, 2016

Study Type : Human Study

Additional Links

Substances : Frankincense, Ginger

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Plant Extracts

[+]

Zingiber mioga reduces weight gain, insulin resistance and hepatic gluconeogenesis in diet-induced obese mice.Jun 30, 2016

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Pubmed Data : Exp Ther Med. 2016 Jul ;12(1):369-376. Epub 2016 May 11. PMID: 27347064

Article Published Date : Jun 30, 2016

Study Type : Animal Study

Additional Links

Substances : Ginger

Diseases : Hepatic Steatosis, Obesity

Pharmacological Actions : Hepatoprotective, Hypolipidemic

Additional Keywords : Anti-Obesity Agents

[+]

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Pubmed Data : Andrologia. 2016 Aug 22. Epub 2016 Aug 22. PMID: 27546232

Article Published Date : Aug 21, 2016

Study Type : Animal Study

Additional Links

Substances : Ginger, Gingerol

Diseases : Endocrine Imbalances

Pharmacological Actions : Antioxidants

Additional Keywords : Plant Extracts

Problem Substances : Endocrine Disrupting Chemicals (EDCs)

[+]

6-Shogaol, a compound found within ginger, exerts a strong anti-inflammatory activity against urate crystal-induced inflammation in mice. Sep 01, 2010

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Pubmed Data : Adv Pharm Bull. 2016 Jun ;6(2):271-4. Epub 2016 Jun 30. PMID: 27478792

Article Published Date : May 31, 2016

Study Type : Animal Study

Additional Links

Substances : Garlic, Ginger, Nutmeg

Diseases : Cadmium Poisoning

Pharmacological Actions : Renoprotective

[+]

Adding ginger to daily diet of diabetic patients has useful effects and may ameliorate diabetes complications.Jun 30, 2019

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Pubmed Data : J Pharm Pharmacol. 2004 Jan ;56(1):101-5. PMID: 14980006

Article Published Date : Dec 31, 2003

Study Type : Animal Study

Additional Links

Substances : Ginger

Diseases : Diabetes Mellitus: Type 1: Prevention, Hypertension

Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing

Additional Keywords : Phytotherapy

Problem Substances : Insulin

[+]

Anti-inflammatory activity of ginger modulates macrophage activation against the inflammatory pathway of monosodium glutamat.Jun 21, 2021

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Pubmed Data : J Food Biochem. 2021 Jun 22:e13819. Epub 2021 Jun 22. PMID: 34159624

Article Published Date : Jun 21, 2021

Study Type : Animal Study

Additional Links

Substances : Ginger

Diseases : Inflammation, Rheumatoid Arthritis, Ulcerative Colitis

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents

Additional Keywords : Polysaccharides

Problem Substances : Monosodium Glutamate (MSG)

[+]

Anti-inflammatory and -apoptotic effects of a long-term herbal extract treatment on DSS-induced colitis.Aug 10, 2021

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Pubmed Data : J Sci Food Agric. 2011 Sep 14. Epub 2011 Sep 14. PMID: 21918995

Article Published Date : Sep 13, 2011

Study Type : Animal Study

Additional Links

Substances : Capsaicin, Ginger, Piperine

Diseases : Fat Malabsorption, Indigestion: Fats, Steatorrhea

Pharmacological Actions : Enzyme Inhibitors: Pancreatic Lipase

[+]

Dietary ginger has a protective effect on lindane-induced oxidative stress in rats.Mar 01, 2008

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Pubmed Data : Altern Med Rev. 2008 Mar;13(1):6-20. PMID: 18389491

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Pubmed Data : J Toxicol. 2018 ;2018:4109491. Epub 2018 Oct 8. PMID: 30402094

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Ginger, Turmeric

Diseases : Cadmium Poisoning

Pharmacological Actions : Acetylcholinesterase Inhibitor, Anti-Inflammatory Agents, Interleukin-10 downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Essential Oils

Problem Substances : Cadmium

[+]

Effects of Zingiber officinale extract supplementation on metabolic and genotoxic parameters in diet-induced obesity.Dec 15, 2020

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Pubmed Data : Br J Nutr. 2020 Dec 16:1-12. Epub 2020 Dec 16. PMID: 33323139

Article Published Date : Dec 15, 2020

Study Type : Animal Study

Additional Links

Substances : Ginger

Diseases : Obesity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Evaluation of antineoplasic activity of Zingiber officinale essential oil in the colorectal region.Jun 30, 2020

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Pubmed Data : Asian Pac J Cancer Prev. 2020 Jul 1 ;21(7):2141-2147. Epub 2020 Jul 1. PMID: 32711443

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Pubmed Data : J Med Food. 2010 Dec ;13(6):1397-401. PMID: 21091253

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Parasitol. 2014 Oct-Dec;9(4):530-40. PMID: 25759734

Article Published Date : Sep 30, 2014

Study Type : Animal Study

Additional Links

Substances : Cinnamon, Ginger

Diseases : Giardiasis

Pharmacological Actions : Antigiardial agents, Antioxidants, Antiprotozoal Agents

Additional Keywords : Plant Extracts, Significant Treatment Outcome

[+]

Ginger and constituent 6-gingerol could be used the prevention or alleviation of allergic rhinitis symptoms.Aug 31, 2015

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Pubmed Data : J Nutr Biochem. 2015 Sep 1. Epub 2015 Sep 1. PMID: 26403321

Article Published Date : Aug 31, 2015

Study Type : Animal Study

Additional Links

Substances : Ginger, Gingerol

Diseases : Allergic Rhinitis, Allergic Rhinitis: Prevention

Pharmacological Actions : Anti-Allergic Agents, Immunomodulatory

[+]

[+]

Ginger contains compounds with significant joint-protective effects in experimental rheumatoid arthritis. Feb 13, 2009

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Pubmed Data : J Nat Prod. 2009 Feb 13. PMID: 19216559

Article Published Date : Feb 13, 2009

Study Type : Animal Study

Additional Links

Substances : Ginger

Diseases : Arthritis: Rheumatoid

[+]

Ginger contains the compound zerumbone, which inhibits colon and lung carcinogenesis in mice.Jan 15, 2009

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Pubmed Data : Int J Cancer. 2009 Jan 15;124(2):264-71. PMID: 19003968

Article Published Date : Jan 15, 2009

Study Type : Animal Study

Additional Links

Substances : Ginger

Diseases : Colon Cancer, Lung Cancer

Pharmacological Actions : Anticarcinogenic Agents, NF-kappaB Inhibitor

[+]

Ginger could protect alcohol-induced myocardial damage by suppression of hyperlipidemia and cardiac biomarkers.Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pharmacogn Mag. 2017 Jan ;13(Suppl 1):S69-S75. Epub 2017 Apr 7. PMID: 28479729

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Pubmed Data : Sci Total Environ. 2019 Nov 3:134664. Epub 2019 Nov 3. PMID: 31757552

Article Published Date : Nov 02, 2019

Study Type : Animal Study

Additional Links

Substances : Ginger

Diseases : Bisphenol Toxicity

Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation

Problem Substances : Bisphenol A

[+]

Ginger extract ameliorates obesity and inflammation. Oct 22, 2018

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Pubmed Data : Iran J Med Sci. 2016 May ;41(3 Suppl):S71. PMID: 27840537

Article Published Date : Apr 30, 2016

Study Type : Animal Study

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Substances : Ginger

Diseases : Alcohol Toxicity

Pharmacological Actions : Prophylactic Agents

Additional Keywords : Plant Extracts

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Ginger extract inhibited cell proliferation and subsequently induced the autotic death of pancreatic cancer Panc-1 cells.Dec 31, 2014

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Pubmed Data : PLoS One. 2015 ;10(5):e0126605. Epub 2015 May 11. PMID: 25961833

Article Published Date : Dec 31, 2014

Study Type : Animal Study

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Substances : 6-Shogaol, Ginger, Gingerol

Diseases : Pancreatic Cancer

Pharmacological Actions : Antiproliferative , Autophagy Up-regulation

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Pharmacological Actions : Antioxidants, Renoprotective

Problem Substances : Cadmium

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Pubmed Data : Chin J Physiol. 2011 Apr 30 ;54(2):79-86. PMID: 21789888

Article Published Date : Apr 30, 2011

Study Type : Animal Study

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Substances : Ginger

Diseases : Diabetes: Kidney Function , Kidney Damage

Pharmacological Actions : Renoprotective

Additional Keywords : Plant Extracts

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Ginger has a protective effect against the development of metabolic syndrome in high-fat diet-fed rats.May 01, 2009

Ginger ingredients could be beneficial in alleviating diabetic prostatic complications through suppressing oxidative stress and tissue fibrosis.Dec 31, 2016

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Pubmed Data : Mol Nutr Food Res. 2007 Dec;51(12):1492-502. PMID: 18030663

Article Published Date : Dec 01, 2007

Study Type : Animal Study

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Substances : Ginger

Diseases : Prostate Cancer

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Ginger protects against reproductive toxicity of aluminium chloride in rats.Jul 26, 2011

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Pubmed Data : Reprod Domest Anim. 2011 Jul 26. Epub 2011 Jul 26. PMID: 21790801

Article Published Date : Jul 26, 2011

Study Type : Animal Study

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Substances : Ginger

Diseases : Aluminum Toxicity

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Pubmed Data : Biomarkers. 2019 Apr 12:1-34. Epub 2019 Apr 12. PMID: 30979347

Article Published Date : Apr 11, 2019

Study Type : Animal Study

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Substances : Ginger

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Hepatoprotective

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Ginger water reduces body weight gain and improves energy expenditure.Jan 01, 2020

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Pubmed Data : Biomed Pharmacother. 2020 Mar 12 ;126:110049. Epub 2020 Mar 12. PMID: 32172063

Article Published Date : Mar 11, 2020

Study Type : Animal Study

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Substances : Fruit Peel, Ginger, Medicinal Mushrooms, Shiitake Mushroom

Diseases : Influenza

Pharmacological Actions : Immunomodulatory, Immunostimulatory

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Nephroprotective effect of essential oils from ginger and turmeric rhizomes against cadmium-induced nephrotoxicity.Dec 31, 2017

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Pubmed Data : J Oleo Sci. 2018 ;67(10):1339-1345. PMID: 30305562

Article Published Date : Dec 31, 2017

Study Type : Animal Study

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Substances : Ginger, Turmeric

Diseases : Kidney Damage: Chemically-Induced

Pharmacological Actions : Adenosine deaminase inhibitor, Anti-Inflammatory Agents, Interleukin-10 downregulation, Interleukin-6 Downregulation, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Essential Oils

Problem Substances : Cadmium

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Neuromodulatory effects of ethyl acetate fraction of Zingiber officinale Roscoe extract in rats with lead-induced oxidative stress.Jan 04, 2019

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Pubmed Data : J Integr Med. 2019 Jan 5. Epub 2019 Jan 5. PMID: 30660591

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Pubmed Data : Nutr Res Pract. 2018 Dec ;12(6):503-511. Epub 2018 Nov 30. PMID: 30515278

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Pubmed Data : Addict Health. 2019 Apr ;11(2):66-72. PMID: 31321003

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Pubmed Data : Masui. 2001 May;50(5):486-90. PMID: 11424461

Article Published Date : May 01, 2001

Study Type : Animal Study

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Substances : Bupleurum, Chinese Skullcap , Cinnamon, Ginger, Japanese Herbal Formula: Sho-saiko-to, Jujube, Licorice, Peony, Pinellia

Diseases : Trigeminal Neuralgia

Pharmacological Actions : Analgesics

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These data provide new insights into the preventive approach of zingerone against the development of the NAFLD.Mar 31, 2016

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Pubmed Data : Gen Physiol Biophys. 2016 Apr ;35(2):185-94. Epub 2016 Feb 26. PMID: 26915720

Article Published Date : Mar 31, 2016

Study Type : Animal Study

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Substances : Ginger, Polyphenols

Diseases : High Fructose Diet, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective

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These findings suggested that Angelica sinensis and Zingiber officinale may be a promising supplement for current IBD therapy.Aug 04, 2019

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Pubmed Data : J Ethnopharmacol. 2016 Aug 2. Epub 2016 Aug 2. PMID: 27496583

Article Published Date : Aug 01, 2016

Study Type : Animal Study

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Substances : Ginger, Turmeric

Diseases : Arsenic Poisoning

Pharmacological Actions : Antioxidants, Cytoprotective, Detoxifier

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Various extracts of ginger inhibit Cytomegalovirus, HSV-1, and HIV virus. Aug 01, 2006

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Pubmed Data : Pharmazie. 2006 Aug;61(8):717-21. PMID: 16964717

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Pubmed Data : Chem Biol Interact. 2018 Feb 1 ;281:106-110. Epub 2017 Dec 28. PMID: 29289488

Article Published Date : Jan 31, 2018

Study Type : Animal Study

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Substances : Ginger, Polyphenols

Diseases : Chemically-Induced Liver Damage, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Hepatoprotective

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Zingerone suppresses angiogenesis via inhibition of matrix metalloproteinases during tumor development.Jul 25, 2016

Zingiber officinale diminishes diazinon-induced hepatotoxicity by suppressing oxidative stress and apoptosis.Jul 15, 2020

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Pubmed Data : Biotech Histochem. 2020 Jul 16:1-7. Epub 2020 Jul 16. PMID: 32672073

Article Published Date : Jul 15, 2020

Study Type : Animal Study

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Substances : Ginger

Diseases : Chemically-Induced Liver Damage, Pesticide Toxicity

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hepatoprotective

Problem Substances : Pesticides

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Zingiber officinale ethanolic extract attenuated reserpine-induced depression.Dec 31, 2019

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Pubmed Data : J Exp Pharmacol. 2020 ;12:439-446. Epub 2020 Nov 2. PMID: 33173355

Article Published Date : Dec 31, 2019

Study Type : Animal Study

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Substances : Ginger

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Problem Substances : Prescription Drugs

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Zingiber officinale extract and 6-gingerol provide protection against acute mercuric chloride-intoxication.May 07, 2017

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Pubmed Data : Biomed Pharmacother. 2017 May 8 ;91:645-655. Epub 2017 May 8. PMID: 28494418

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Pubmed Data : Biochem Biophys Res Commun. 2009 Apr 24;382(1):134-9. Epub 2009 Mar 4. PMID: 19268427

Article Published Date : Apr 24, 2009

Study Type : In Vitro Study

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Substances : Ginger

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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6-paradol effectively protects brain after cerebral ischemia, likely by attenuating neuroinflammation in microglia.Dec 31, 2014

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Pubmed Data : PLoS One. 2015 ;10(3):e0120203. Epub 2015 Mar 19. PMID: 25789481

Article Published Date : Dec 31, 2014

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Pubmed Data : Bioorg Med Chem Lett. 2017 02 15 ;27(4):1081-1088. Epub 2016 Dec 20. PMID: 28110870

Article Published Date : Jan 14, 2017

Study Type : In Vitro Study

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Substances : Ginger, Polyphenols

Diseases : Cancer Metastasis, Liver Cancer

Pharmacological Actions : Anti-metastatic

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A review of ginger in the prevention of ageing and degenerative diseases.Dec 31, 2018

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Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:5054395. Epub 2019 Aug 20. PMID: 31531114

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Pubmed Data : Asian Pac J Trop Med. 2016 Aug ;9(8):730-4. Epub 2016 Jun 28. PMID: 27569880

Article Published Date : Jul 31, 2016

Study Type : Review

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Substances : Capparis spinosa (caper), Ginger, Juniper, Myrrh, Sophora Flavescens, Tongkat Ali, Turmeric

Diseases : Toxoplasma gondii Infection

Pharmacological Actions : Antiparasitic Agents

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A review of the health promoting aspects of ginger in the treatment and prevention of diseases via immunonutrition and anti-inflammatory responses. Mar 31, 2013

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Pubmed Data : Int J Prev Med. 2013 Apr ;4(Suppl 1):S36-42. PMID: 23717767

Article Published Date : Mar 31, 2013

Study Type : Review

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Substances : Ginger

Diseases : Cancers: All, Inflammation, Liver Disease: Oxidative Stress, Muscle Soreness

Therapeutic Actions : Exercise

Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Antioxidants, Antiproliferative , Apoptotic, Gastrointestinal Agents

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Diseases : Bacterial Infections: Resistance/Biofilm Formation, Infection: Antibiotic Resistant

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Anticancer efficacy of 6-gingerol with paclitaxel against wild type of human breast adenocarcinoma.Apr 21, 2022

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Pubmed Data : Biomed Biochim Acta. 1984;43(8-9):S335-46. PMID: 6440548

Article Published Date : Jan 01, 1984

Study Type : In Vitro Study

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Substances : Garlic, Ginger, Onion

Diseases : Thrombosis

Pharmacological Actions : Anti-Platelet, Anti-thrombotic

Additional Keywords : Plant Extracts

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Benefits of ginger and Its constituent 6-shogaol in inhibiting inflammatory processes.Jun 14, 2021

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Pubmed Data : Clin Nutr ESPEN. 2021 06 ;43:9-15. Epub 2021 Apr 24. PMID: 34024569

Article Published Date : Dec 31, 2020

Study Type : Review

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Substances : Garlic, Ginger, Omega-3 Fatty Acids, Onion, Saffron, Turmeric, Vitamin C, Vitamin D, Zinc

Diseases : Adenoviridae Infections, Coronavirus Infection, Inflammation, Influenza, Rhinovirus Infection , Upper Respiratory Infections

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

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Clinical trials on pain lowering effect of ginger: A narrative review May 19, 2020

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Pubmed Data : Phytother Res. 2020 May 20. Epub 2020 May 20. PMID: 32436242

Article Published Date : May 19, 2020

Study Type : Review

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Substances : Ginger

Diseases : Chronic Pain

Pharmacological Actions : Analgesics

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Collectively these RCTs provide suggestive evidence for the effectiveness of 750-2000 mg ginger powder during the first 3-4 days of menstrual cycle for primary dysmenorrhea.Jul 13, 2015

Ginger displayed significant efficacy with regard to controlling chemotherapy-induced nausea and vomiting in the experimental groups.Oct 05, 2018

Ginger is an alternative for the prevention of postoperative nausea and vomiting.Nov 14, 2018

The present systematic review and meta-analysis suggests that ginger had a favorable effect on triacylglycerol and low density lipoprotein cholesterol.Mar 31, 2018

Zingiberaceae extracts are clinically effective hypoalgesic agents and the available data show a better safety profile than non steroidal anti inflammatory drugs.Dec 31, 2014

3 months supplementation of ginger improved glycemic indices, TAC and PON-1 activity in patients with type 2 diabetes.Feb 09, 2015

6-shogaol caused a decrease in serum ferritin levels in 3 of 6 patients with early Myelodysplastic syndrome.Dec 31, 2016

A comparison between the effects of ginger, pyridoxine (vitamin B6) and placebo for the treatment of the first trimester nausea and vomiting of pregnancy.Sep 30, 2018

A highly standardised ginger and Echinacea extract could be beneficial for people with knee osteoarthritis.Oct 12, 2016

A standardized extract of ginger and artichoke significantly promoted gastric emptying in healthy volunteers.Dec 31, 2015

A statistically significant change from baseline for health related quality of life was detected after ginger essential oil inhalation.May 31, 2015

Adjuvant ginger supplementation is associated with better chemotherapy-induced nausea-related quality of life and less cancer-related fatigue.Aug 11, 2017

Aroma-massage therapy with ginger and orange oil have potential as an alternative method for short-term knee pain relief.May 01, 2006

Aromatherapy can be used as an alternative or complementary method for managing PONV.Jan 31, 2019

Aromatherapy demonstrated a statistically significant reduction in the need for antiemetics to treat postoperative nausea and vomiting.May 26, 2019

Aromatherapy is promising as an inexpensive, noninvasive treatment for postoperative nausea that can be administered and controlled by patients as needed.Aug 31, 2013

Aromatherapy massage performed in elderly patients with knee osteoarthritis reduced pain and improved functional status and quality of life.May 29, 2019

Aromatherapy with light Thai massage can be beneficial for the immune systems of cancer patients who are undergoing chemotherapy.Dec 31, 2012

Ayurvedic polyherbal combination for prediabetes.Jan 16, 2019

Comparable efficacy of standardized Ayurveda formulation and hydroxychloroquine sulfate (HCQS) in the treatment of rheumatoid arthritis (RA).Jan 31, 2012

Comparison of the effect of ginger and aloe vera mouthwashes on xerostomia in patients with type 2 diabetes. Jun 30, 2021

Daily administration of 1,000 mg ginger reduces serum triglyceride concentration, which is a risk factor for cardiovascular disease in peritoneal dialysis patients.Oct 15, 2015

Daily supplement of ginger extract started 3 days prior to chemotherapy has been shown to significantly elevate antioxidant activity.Dec 31, 2016

Effect of treatment with ginger on the severity of premenstrual syndrome symptoms.Dec 31, 2013

Effectiveness of a nutraceutical supplement containing highly standardized perilla and ginger extracts in patients with functional dyspepsia.Feb 29, 2020

Effectiveness of ginger powder for the management of pain and gingival inflammation following open flap debridement is comparable to that of ibuprofen.Jul 01, 2020

Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea.Jun 30, 2012

Ginger and artichoke leaf extracts appears efficacious in the treatment of functional dyspepsia and could represent a promising and safe treatment strategy for this frequent disease.Dec 31, 2014

Ginger and chamomile were both significantly effective for reducing the frequency of vomiting.Dec 31, 2015

Ginger and cinnamon intake have positive effects on inflammation and muscle soreness endued by exercise in Iranian female athletes.Mar 31, 2013

Ginger and Vitamin B6 are both effective in treating naseau and vomiting in pregnancy. Feb 11, 2008

Ginger as well as Novafen is effective in relieving pain in girls with primary dysmenorrhea.Nov 30, 2018

Ginger can improve rheumatoid arthritis by decreasing disease manifestations in patients.May 24, 2019

Ginger compares favorably to the drug sumatriptan for migraine headaches, but with lower side effects. May 08, 2013

Ginger consumption enhances the thermic effect of food and promotes feelings of satiety without affecting metabolic and hormonal parameters in overweight men.Sep 30, 2012

Ginger extract can be used for the prevention of nausea and vomiting during cesarean section under spinal anesthesia.Sep 30, 2016

Ginger extract reduces delayed gastric emptying and nosocomial pneumonia in adult respiratory distress syndrome patients hospitalized in an intensive care unit.Feb 09, 2010

Ginger has a beneficial effect on type 2 diabetics.Mar 17, 2013

Ginger has a significant lipid lowering effect compared to placebo. Sep 01, 2008

Ginger has a therapeutic effect on motion sickness. Jan 01, 2007

Ginger has reduces symptoms of osteoarthritis of the knee. Nov 01, 2001

Ginger improves oxidative stress and trace elements status in patients with alopecia areata.Oct 31, 2020

Ginger is a potential cognitive enhancer for middle-aged women.Jan 01, 2012

Ginger is a promising natural galactagogue to improve breast milk volume in the immediate postpartum period without any notable side effect.Aug 08, 2016

Ginger is an aldose reductase inhibitor which may have contribute to the protection against diabetic complications. Sep 06, 2006

Ginger is an effective supplement for heavy menstrual bleeding. Oct 07, 2014

Ginger is as effective as mefenamic acid and ibuprofen in relieving pain in women with primary dysmenorrrhea. Feb 13, 2009

Ginger powder supplementation can reduce inflammatory markers in patients with knee osteoarthritis.Jun 30, 2016

Ginger reduces chemotherapy-induced nausea. Feb 07, 2012

Ginger reduces the tendency to vomiting and cold sweating due to seasickness significantly better than placebo. Jan 01, 1988

Ginger root powder is effective in reducing severity of acute and delayed chemotherapy-induced nausea and vomiting as additional therapy to ondensetron and dexamethasone in patients receiving chemotherapy.Sep 14, 2010

Ginger root reduces vertigo in human subjects. Jan 01, 1986

Ginger stimulates gastric emptying in patients with functional dyspepsia. Jan 07, 2011

Ginger supplement along with NSPT may be effective in the improvement of inflammation, oxidative, and periodontal status in T2DM with chronic periodontitis.Dec 31, 2018

Ginger supplementation is an effective treatment for type 2 diabetes. Feb 03, 2014

Ginger supplementation may be used to accelerate recovery of muscle strength following intense exerciseMay 31, 2015

Ginger supplementation offers beneficial effects on patients with metabolic syndrome.May 31, 2019

Ginger supplementation with antitubercular treatment significantly lowered TNF alpha, ferritin and MDA concentrations.May 31, 2016

Ginger syrup may be effective as an antiemetic in early pregnancy.Sep 01, 2002

Ginger-indirect moxibustion plus acupuncture versus acupuncture alone for chronic fatigue syndrome.Mar 31, 2022

Ginger-salt moxibustion is therapeutic for poststroke urinary disorders. Sep 01, 2006

Herbal formulation turmeric extract, black pepper, and ginger versus naproxen for chronic knee osteoarthritis.Jul 31, 2020

Lavender and ginger oil reduce distress levels in children before undergoing anesthesia. Oct 01, 2009

Nausea severity and the number of vomiting episodes were significantly lower in the Ginger intervention group than in the control group.Sep 30, 2015

Prebiotic potential of culinary spices used to support digestion and bioabsorption.Dec 31, 2018

Protein and ginger may have therapeutic value in the treatment of chemotherapy-induced delayed nausea.Jun 01, 2008

Self-knee massage with ginger oil in patients with osteoarthritis.Oct 31, 2017

The effect of ginger in patients with advanced cancer.Nov 18, 2019

The effect of ginger powder supplementation on insulin resistance and glycemic indices in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled trial.Jan 31, 2014

The effects of combination of Zingiber officinale and Echinacea on alleviation of clinical symptoms and hospitalization rate of suspected COVID-19 outpatients.Mar 30, 2021

The gastro-protective effect of ginger in Helicobacter pylori positive functional dyspepsia.May 31, 2019

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View the Evidence:
413 Abstracts with Ginger Research