Ginseng

Name	AC	CK
Oxidative Stress	54	142
Diabetes Mellitus: Type 2	32	121
Hypertension	11	82
Liver Cancer	39	82
Alzheimer's Disease	50	78
Inflammation	50	78
Obesity	37	73
Colorectal Cancer	22	70
Lung Cancer	42	64
Cancers: All	29	55
Breast Cancer	40	54
Depression	26	53
Lipopolysaccharide-Induced Toxicity	33	49
Stroke: Ischemic	9	49
Nonalcoholic fatty liver disease (NAFLD)	16	47
DNA damage	8	46
Parkinson's Disease	17	46
HIV Infections	7	45
Memory Disorders	17	45
Cognitive Decline/Dysfunction	18	42
Myocardial Ischemia	20	42
Chemotherapy-Induced Toxicity: Cisplatin	21	41
Carcinoma: Non-Small-Cell Lung	9	38
Cerebral Ischemia	19	33
Aging Skin	4	32
Influenza A	8	32
Colon Cancer	19	31
Fatigue	8	30
Gastric Cancer	10	30
Brain Ischemia	11	29
Esophageal Cancer	6	28
High Fat Diet	12	26
Pancreatic Cancer	5	26
Radiation Induced Illness	5	26
Aging: Brain	8	25
Atopic Dermatitis	8	25
Brain Inflammation	15	25
Diabetes Mellitus: Type 1	12	25
Cancers: Drug Resistant	14	24
Chemically-Induced Liver Damage	13	24
Diabetic Complications	12	24
Acetaminophen (Tylenol) Toxicity	10	22
Attention Deficit Disorder with Hyperactivity	3	22
Common Cold	3	21
Ovarian Cancer	16	21
Cancer: Fatigue	2	20
Cardiovascular Diseases	11	20
Chemotherapy Induced Myelotoxicity	1	20
Cholesterol: High	1	20
Dry Eye Syndromes	1	20
Lipid Peroxidation	6	20
Low Immune Function: Natural Killer Cells	2	20
Melanoma	14	20
Upper Respiratory Infections	2	20
Colitis	10	19
Neurodegenerative Diseases	14	19
Heart Failure	6	18
Chemotherapy-Induced Toxicity: Cyclophosphamide	10	17
Spinal Cord Injuries	10	17
Stroke	5	17
Wound Healing	8	17
Erectile Dysfunction	5	16
Hair Loss	5	16
Hypoxia	12	16
Insulin Resistance	10	16
Sepsis	10	16
Aging	7	15
Atherosclerosis	10	15
Cancer Metastasis	14	15
Leukemia: Acute myelogenous leukemia (AML)	5	15
Myocardial Infarction	9	15
Respiratory Syncytial Virus Infections	4	15
Chronic Obstructive Pulmonary Disease	3	14
Hydrogen Peroxide Induced Toxicity	12	14
Stress	3	14
Chronic Kidney Disease (CKD)	3	13
Helicobacter Pylori Infection	3	13
Huntington Disease	4	13
Liver Fibrosis	6	13
Osteoarthritis	6	13
Alcoholic Liver Disease	6	12
Athletic Performance	2	12
Congestive Heart Failure	2	12
Diabetic Nephropathy	6	12
Infertility: Male	2	12
Sarcopenia	2	12
Schizophrenia	2	12
Alopecia: Androgenic	2	11
Chemotherapy-Induced Toxicity: Doxorubicin	7	11
Cholesterol: Oxidation	2	11
Halitosis	2	11
Hepatitis B	2	11
Hyperglycemia	5	11
Prostate Cancer	10	11
Respiratory Diseases	2	11
Sperm Quality: Low	2	11
Ultraviolet Radiation Induced Damage	8	11
Acne	1	10
Acquired Immunodeficiency Syndrome	1	10
Acute Respiratory Distress Syndrome	1	10
Air Pollution Linked Toxicity	3	10
Alcohol Toxicity	5	10
Arterial Hardening: Elasticity	1	10
Asthenozoospermia	1	10
Bisphenol-A Toxicity	1	10
Breast Cancer: Triple Negative	8	10
Cervical Cancer	8	10
Chemotherapy-Induced Toxicity: Oxaliplatin	1	10
Chronic Fatigue Syndrome	1	10
Cold and Flu	1	10
Cold: Common	1	10
Flu	1	10
Human Flu	1	10
Human Influenza	1	10
Hypothyroidism	1	10
Immune Disorders: Low Immune Function	1	10
Ischemia	6	10
Liver Damage	5	10
Lower Respiratory Infections	1	10
Postmenopausal Disorders	1	10
Testosterone: Too High	1	10
Tinnitus	1	10
Diabetic Retinopathy	5	9
Endometriosis	5	9
Glioblastoma	6	9
Leukemia	8	9
Lung Injury: Acute	5	9
Skin Cancer	7	9
Alopecia	3	8
Arthritis	4	8
Cardiac Hypertrophy	4	8
Dementia	5	8
Fatigue: Excercise-Induced	3	8
Hyperlipidemia	3	8
Memory Disorders: Drug-Induced	3	8
Multiple Sclerosis	5	8
Osteoporosis	6	8
Rheumatoid Arthritis	4	8
Autoimmune Diseases	3	7
Chemotherapy and Radiation Toxicity	2	7
Glioma	6	7
H1N1 Infection	3	7
Learning disorders	4	7
Lung Injury: Smoke-Induced	4	7
Psoriasis	4	7
Squamous cell carcinoma	6	7
Allergic Rhinitis	2	6
Brain: Microglial Activation	5	6
Chemotherapy-Induced Toxicity: 5-fluorouracil	2	6
Hepatic Steatosis	3	6
Hypertension: Pulmonary	3	6
Inflammatory Bowel Diseases	4	6
Itching	2	6
Liver Failure: Acute	2	6
Osteosarcoma	6	6
Ovarian Failure	3	6
Polycystic Ovary Syndrome	3	6
Promyelocytic leukemia	5	6
Pseudomonas aeruginosa	3	6
Staphylococcus aureus infection	3	6
Asthma	3	5
Bisphenol Toxicity	3	5
Dermatitis	3	5
Dyslipidemias	3	5
Hearing Loss: Noise-Induced	2	5
Kidney Fibrosis	3	5
Metabolic Diseases	3	5
Myocardial Fibrosis	3	5
Scars	3	5
Stroke: Attenuation/Recovery	3	5
Acute Myeloid Leukemia	4	4
Anxiety	2	4
Burns	2	4
Cardiomyopathy	2	4
Chemotherapy-Induced Kidney Damage	2	4
Chronic Pain	2	4
Diabetes: Cardiovascular Illness	2	4
Diabetes: Cognitive Dysfunction	2	4
Diabetes: Oxidative Stress	2	4
Encephalomyelitis	1	4
Endometrial Cancer	3	4
Endothelial Dysfunction	3	4
Fatigue: Cancer-Associated	1	4
Fatty Liver	2	4
Gastric Ulcer	2	4
Gastritis	2	4
Intestinal Ischemia	2	4
Kidney Damage	2	4
Kidney Failure: Acute	2	4
Liver Disease	3	4
Low Libido	2	4
Metabolic Syndrome X	2	4
Mitochondrial Dysfunction	3	4
Morphine Tolerance/Dependence	1	4
Muscle Atrophy	3	4
Nasopharyngeal Cancer	4	4
Neuroblastoma	3	4
Radiation-Induced Illness: Cesium-137 Exposure	3	4
Skin Diseases: Photo-Aging	2	4
Sleep Disorders	2	4
Testicular Injury: Chemical/Metal Induced	2	4
Ulcerative Colitis	2	4
Allergies	2	3
Aluminum Toxicity	2	3
Amyotrophic lateral sclerosis (ALS)	2	3
Breast Cancer: Metastatic	1	3
Cancers: Multi-Drug Resistant	2	3
Cataract	2	3
Central Nervous System Diseases	2	3
Coxsackievirus Infections	3	3
Escherichia coli Infections	2	3
Gallbladder Cancer	2	3
Gastrointestinal polyps	2	3
Liver Cirrhosis	2	3
Multiple Myeloma	3	3
Tertiary butyl hydroperoxide toxicity	2	3
Thyroid Cancer	2	3
Vaginal Cancer	2	3
Acute T cell Leukemias	2	2
Adiponectin: Low Levels	1	2
Advanced Glycation End products (AGE)	1	2
Allodynia	1	2
Anemia	1	2
Anemia: Iron Deficiency	1	2
Aneurysm: Aortic	1	2
Anti-Glomerular Basement Membrane Disease	1	2
Arthritis: Rheumatoid	1	2
Bladder Cancer	2	2
Brain Cancer	2	2
Brain: Oxidative Stress	1	2
Cachexia	1	2
Cancer: Pain	1	2
Candida Albicans	1	2
Cardiomegaly	1	2
Cerebral Aneurysm	1	2
Chemobrain	1	2
Chemotherapy-Induced Neurotoxicity	1	2
Chemotherapy-Induced Toxicity: Adriamycin	1	2
Chemotherapy-Induced Toxicity: Bleomycin	1	2
Colitis: Pseudomembranous	1	2
Colon Cancer: Prevention	1	2
Colon Polyps	1	2
Degenerative Disk Disease	2	2
Depression	1	2
Diabetes Mellitus: Type 1: Prevention	1	2
Diabetes: Kidney Function	1	2
Diabetic Ulcer	1	2
Diarrhea: Antibiotic-Associated	1	2
Diarrhea: Drug-Associated	1	2
Drug Toxicity: Cephaloridine	1	2
Drug-Induced Toxicity: Cyclosporine	1	2
Dysbiosis	1	2
Dysmenorrhea	1	2
Encephalopathy	1	2
Epilepsy	1	2
Exercise-Induced Tissue Damage	1	2
Fluoride Toxicity	1	2
Gastric Ulcers	1	2
H5N1 Infection	1	2
Hashimoto's thyroiditis	1	2
Hepatitis A	2	2
Hepatitis C	2	2
Herbicide Toxicity	1	2
Herpes Simplex Virus Type 1	2	2
Herpes family viruses	1	2
High Sugar Diet	1	2
Hypercapnia	1	2
Hypercholesterolemia	1	2
Hyperhomocysteinemia	2	2
Hypoglycemia	1	2
Inappropriate Luteinizing Hormone Secretion	1	2
Infertility: Female	1	2
Intoxication	1	2
Ischemia: Myocardial	1	2
Kawasaki Disease	1	2
Keloid	1	2
Leukemia: Acute promyelocytic leukemia	2	2
Leukemia: Chronic myelogenous leukemia (CML)	2	2
Liver Damage: Drug-Induced	1	2
Liver Steatosis	1	2
Low Testosterone	1	2
Lymphoma	1	2
Male Reproductive Development Abnormalities	1	2
Mastitis	1	2
Melanoma: Metastasis	1	2
Middle Cerebral Artery Occlusion (MCAO)	1	2
Mitochondrial Diseases	2	2
Mood Disorders	1	2
Nerve Injuries	1	2
Obstructive Nephropathy	1	2
Oral Cancer	1	2
Pain	1	2
Pancreatic Diseases	1	2
Pneumonia	1	2
Post-Traumatic Stress Disorders (PTSD)	1	2
Postoperative Recovery	1	2
Prostatic Hyperplasia: Benign	1	2
Prostatitis: Bacterial	1	2
Pruritus	1	2
Pulmonary Fibrosis: Bleomycin-Induced	1	2
Radiation-Induced Illness: Radioiodine (Iodine-131)	1	2
Rhinovirus Infection	2	2
Right Ventricular Hypertrophy	1	2
Rotavirus Infections	1	2
Sciatic Nerve Crush Injury	1	2
Sciatica	1	2
Smoking: Pulmonary	1	2
Streptococcus pneumoniae infection	1	2
Subarachnoid hemorrhage	1	2
Testosterone: Too Low	1	2
Toxoplasma gondii Infection	1	2
Toxoplasmosis	1	2
Triglycerides: Elevated	1	2
Acute lymphoblastic leukemia (ALL)	1	1
Aging: Heart	1	1
Benzo[a]pyrene-induced Toxicity	1	1
Bone Diseases	1	1
Brain Hypoxia	1	1
Brain Injury: Hippocampal Damage	1	1
Brain Injury: Traumatic	1	1
C-Reactive Protein	1	1
Candidiasis	1	1
Cocaine Withdrawal	1	1
Coronavirus Infection	1	1
Cystic Fibrosis	1	1
Demyelinating Diseases	1	1
Dental Caries	1	1
Endothelial Damage	1	1
Enterovirus	1	1
Enterovirus 71	1	1
Enterovirus: Type 71	1	1
Excitotoxicity	1	1
Fibroma: Uterine	1	1
Fibrosarcoma	1	1
Fibrosis	1	1
Gastrointestinal Cancer	1	1
Glioblastoma Multiforme	1	1
Glioma: Astrocytic	1	1
H3N2 Infection	1	1
HIV Protease Inhibitor Ritonavir Toxicity	1	1
Hangover	1	1
Heart Disease: Ischemic	1	1
Herpes Simplex Virus Type 2	1	1
Histamine: Elevated	1	1
Homocysteine: Elevated	1	1
Immune Dysregulation: TH1 dominance	1	1
Immune Dysregulation: TH1/TH2 imbalance	1	1
Influenza	1	1
Kidney Cancer	1	1
Kidney Damage: Chemically-Induced	1	1
Kidney Failure	1	1
Lead Poisoning	1	1
Leukemia: Multi-Drug Resistant	1	1
Leukemia: T-cell acute Lymphoblastic	1	1
Liver Injury: Ischemia/reperfusion	1	1
Lung Inflammation	1	1
Medulloblastoma	1	1
Melasma	1	1
Neurological Conditions	1	1
Non-Small-Cell Lung Carcinoma	1	1
Norovirus	1	1
Organ Transplantation	1	1
Parasitic Diseases	1	1
Peritonitis	1	1
Pesticide Toxicity	1	1
Porphyromonas gingivalis	1	1
Prion Diseases	1	1
Progesterone: Low	1	1
Rectal Cancer	1	1
Retinal Diseases	1	1
Retinoblastoma	1	1
Scars: Hyperplastic	1	1
Schwannoma: Vestibular	1	1
Stem Cell Transplant	1	1
Steptococcus Mutans Infections	1	1
Surgery: Anesthesiology	1	1
Tachycardia	1	1
Vascular Calcification	1	1
Wrinkles	1	1
Cortisone Toxicity	1	0

Name	AC	CK
Anti-Inflammatory Agents	217	456
Neuroprotective Agents	178	389
Antioxidants	151	363
Antiproliferative	154	229
Apoptotic	157	197
Anti-Apoptotic	83	151
Tumor Necrosis Factor (TNF) Alpha Inhibitor	83	150
Hepatoprotective	65	144
Chemoprotective Agents	41	125
Cardioprotective	70	121
Interleukin-1 beta downregulation	64	116
Chemotherapeutic	48	108
Interleukin-6 Downregulation	53	106
Anti-metastatic	62	105
NF-kappaB Inhibitor	61	102
Immunomodulatory	38	99
Hypoglycemic Agents	28	86
Hypolipidemic	20	67
Angiogenesis Inhibitors	19	64
Antihypertensive Agents	9	62
Chemosensitizer	24	60
Chemopreventive	22	59
Cyclooxygenase 2 Inhibitors	35	54
Matrix metalloproteinase-2 (MMP-2) inhibitor	27	53
Antidepressive Agents	25	51
Malondialdehyde Down-regulation	20	45
Nrf2 activation	28	45
Antiviral Agents	16	42
Renoprotective	20	42
Cell cycle arrest	34	41
Matrix metalloproteinase-9 (MMP-9) inhibitor	21	39
Anti-Fibrotic	16	37
Antineoplastic Agents	31	37
Superoxide Dismutase Up-regulation	15	37
Vascular Endothelial Growth Factor Inhibitors	20	36
Immunostimulatory	12	34
Radioprotective	9	33
MicroRNA modulator	21	30
Antimicrobial	6	26
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	13	25
Anticholesteremic Agents	3	24
Gastrointestinal Agents	13	24
Neurogenesis	3	24
Anti-Angiogenic	9	21
Anti-HIV Agents	2	21
Brain-derived neurotrophic factor modulator	11	21
Autophagy Up-regulation	14	20
HIV Protease Inhibitors	1	20
Bcl-2 protein down-regulation	14	17
Heme oxygenase-1 up-regulation	10	17
Tumor Suppressor Protein p53 Upregulation	13	17
Cytoprotective	8	15
Gastroprotective	8	15
Pancreato Protective Agents	6	14
Regenerative	3	13
Anticarcinogenic Agents	7	12
Genoprotective	2	12
Interleukin-18 down-regulation	6	12
Nitric Oxide Inhibitor	8	12
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	11
Photoprotective	8	11
Autophagy Inhibitors	7	10
Interleukin-4 downregulation	5	10
Tumor Necrosis Factor (TNF) Alpha Enhancer	1	10
Angiogenesis Inducing Agents	5	9
Osteoprotective	6	9
Transforming growth factor beta (TGF-β) inhibitor	6	9
Wnt/β-catenin signaling pathway modulation	7	8
Chondroprotective	2	7
Immunomodulatory: Th17 downregulation	3	7
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	3	7
Neuritogenic	5	7
Analgesics	3	6
Anti-atherogenic	3	6
Antinoceceptive	3	6
Antipruritics	2	6
Histone deacetylase inhibitor	4	6
Interleukin-8 downregulation	4	6
SIRT1 Activator	4	6
interleukin-13 down-regulation	2	6
Fertility Agents: Male	3	5
Interferon Gamma Reducer	3	5
Prophylactic Agents	3	5
Prostaglandin PGE2 downregulation	1	5
Secretagogue	3	5
Anti-Adipogenic	2	4
Anti-Anxiety Agents	2	4
Anti-Platelet	1	4
Anti-Ulcer Agents	2	4
Aphrodisiac	2	4
Enzyme Inhibitors	3	4
Interleukin-10 upregulation	2	4
Interleukin-17 downregulation	2	4
Interleukin-5 downregulation	1	4
Postaglandin PGE2 downregulation	2	4
Radiosensitizer	3	4
Vascular Endothelial Growth Factor A Inhibitor	2	4
Vasodilator Agents	2	4
Viral Hemagglutinin Inhibitor	1	4
Anti-Bacterial Agents	2	3
Heat Shock Protein Down-Regulation	2	3
Insulin Sensitizers	2	3
P21 Activation	2	3
Telomerase Inhibitor	2	3
Transforming growth factor beta (TGF-β) upregulation	2	3
Acetylcholinesterase Inhibitor	1	2
Adiponectin upregulation	1	2
Alpha-amylase inhibitor	1	2
Analgesics: Non-Narcotic	1	2
Anticoagulants	1	2
Anticonvulsants	1	2
Antimutagenic Agents	1	2
Caspase-3 Activation	1	2
Caspase-8 activation	1	2
Catalase Up-Regulation	1	2
DNA Repair Up-regulation	2	2
E-cadherin down-regulation	1	2
Epidermal growth factor receptor (EGFR) inhibitor	1	2
Fertility Agents: Female	1	2
GABA Modulators	1	2
Glucose transporter-2 (GLUT2) expression down-regulation	1	2
Heme oxygenase-1 inducer	2	2
Histamine Agents	1	2
Immunomodulatory: Regulatory T Cell Up-Regulation	1	2
Immunosuppressive Agents	1	2
Interleukin-10 downregulation	1	2
Interleukin-2 upregulation	1	2
Interleukin-22 Downregulation	1	2
Interleukin-23 Downregulation	1	2
Matrix Metalloproteinase-7 (MMP-7) Inhibitor	2	2
Multidrug Resistance Gene Modulators	1	2
Neurorestorative	1	2
Nitric Oxide Enhancer	1	2
Paraptosis	2	2
STAT3 Inhibitor	1	2
Vascular Endothelial Growth Factor C Inhibitor	1	2
Vascular Endothelial Growth Factor Regulator	2	2
Acetylcholinesterase Down-Regulation	1	1
Anti-Retroviral Agents	1	1
Antifungal Agents	1	1
Antiparasitic Agents	1	1
Cholinesterase Inhibitors	1	1
Cyclin D1 Down-Regulation	1	1
Dopaminergic	1	1
Glucagon Like peptide 1 (GLP-1) Up-regulation	1	1
Hematologic Agents	1	1
Histamine down-regulation	1	1
Insulin-Like Growth Factor Enhancer/Upregulation	1	1
Insulin-releasing	1	1
Interleukin-1 alpha downregulation	1	1
Interleukin-12 downregulation	1	1
Osteogenic	1	1
Survivin Down-Regulation	1	1
Vascular Endothelial Growth Factor A Enhancer	1	1
Vasoprotective	1	1

Pubmed Data : Nutr Neurosci. 2019 Nov 18:1-12. Epub 2019 Nov 18. PMID: 31736428

Article Published Date : Nov 17, 2019

Study Type : Human Study

Additional Links

Substances : Bacopa, Coffee, Ginseng (American)

Diseases : Memory Disorders

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Natural Substance Synergy

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AGM possibly improves insulin sensitivity and β-cell function and reduces liver damage and inflammation in prediabetic adults.Jul 04, 2021

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Pubmed Data : Foods. 2021 Jul 5 ;10(7). Epub 2021 Jul 5. PMID: 34359426

American Ginseng is safe and effective in reducing relative risk and duration of respiratory symptoms associated with "cold and flu" in adults. Mar 01, 2006

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Pubmed Data : J Altern Complement Med. 2006 Mar;12(2):153-7. PMID: 16566675

Article Published Date : Mar 01, 2006

Study Type : Human Study

Additional Links

Substances : Ginseng (American)

Diseases : Cold: Common, Common Cold, Human Flu, Human Influenza, Influenza A

Pharmacological Actions : Antiviral Agents

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American ginseng is safe, well tolerated, and potentially effective for preventing acute respiratory illness due to influenza and respiractory syncytial virus infections.Jan 01, 2004

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Pubmed Data : J Am Geriatr Soc. 2004 Jan;52(1):13-9. PMID: 14687309

Daily supplementation with fermented red ginseng lowered postprandial glucose levels in subjects with impaired fasting glucose or type 2 diabetes.Jul 10, 2014

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Ginseng could improve glucose control and insulin sensitivity in patients with T2DM or impaired glucose intolerance.Jan 31, 2016

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Pubmed Data : Medicine (Baltimore). 2016 Feb ;95(6):e2584. PMID: 26871778

Article Published Date : Jan 31, 2016

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Pubmed Data : J Ginseng Res. 2021 Jan ;45(1):191-198. Epub 2020 Sep 16. PMID: 33437171

Article Published Date : Dec 31, 2020

Study Type : Human Study

Additional Links

Substances : Ginseng (Korean)

Pharmacological Actions : Immunostimulatory

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In this preliminary study korean red ginseng significantly lowered the incidences of acute respiratory infections. Nov 30, 2012

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Pubmed Data : J Korean Med Sci. 2012 Dec ;27(12):1472-8. Epub 2012 Dec 7. PMID: 23255845

Article Published Date : Nov 30, 2012

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Pubmed Data : Eur J Cancer. 2020 May ;130:51-62. Epub 2020 Mar 13. PMID: 32172198

Article Published Date : Apr 30, 2020

Study Type : Human Study

Additional Links

Substances : Ginseng (Korean)

Diseases : Cancer: Fatigue, Colorectal Cancer

Pharmacological Actions : Chemotherapeutic

[+]

Korean red ginseng lowers urinary BPA levels and BPA-induced malondialdehyde levels and alleviates gynecological complaints without side effects of raw-ginseng.Dec 31, 2013

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Pubmed Data : BMC Complement Altern Med. 2014 ;14:265. Epub 2014 Jul 25. PMID: 25063041

Article Published Date : Dec 31, 2013

Study Type : Human Study

Additional Links

Substances : Ginseng (Korean)

Diseases : Bisphenol-A Toxicity, Oxidative Stress

Pharmacological Actions : Chemopreventive, Malondialdehyde Down-regulation

Additional Keywords : Detoxification, Plant Extracts

Problem Substances : Bisphenol A

[+]

Pharmacological Actions : Matrix metalloproteinase-2 (MMP-2) inhibitor

Additional Keywords : Plant Extracts

[+]

The combination of transcatheter arterial chemoembolization and ginsenoside Rg3 may prolong overall survival when compared with it alone.Jul 31, 2016

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Pubmed Data : Food Funct. 2022 Apr 4 ;13(7):3793-3811. Epub 2022 Apr 4. PMID: 35316310

Article Published Date : Apr 03, 2022

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Liver Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

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Ginsenoside Rb2 improves insulin resistance by inhibiting adipocyte pyroptosis.Nov 30, 2020

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Pubmed Data : Adipocyte. 2020 Dec ;9(1):302-312. PMID: 32580621

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Pubmed Data : J Ginseng Res. 2021 Jul ;45(4):498-509. Epub 2021 Jan 16. PMID: 34295210

Article Published Date : Jun 30, 2021

Study Type : Animal Study

Additional Links

Substances : Ginseng

Diseases : Ultraviolet Radiation Induced Damage

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Photoprotective

Additional Keywords : Hair Regeneration

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The dual roles of ginsenosides in improving the anti-tumor efficiency of cyclophosphamide in mammary carcinoma mice. Aug 23, 2020

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Pubmed Data : J Ethnopharmacol. 2020 Aug 24:113271. Epub 2020 Aug 24. PMID: 32853742

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Pubmed Data : Food Sci Biotechnol. 2018 Aug ;27(4):1193-1200. Epub 2018 Apr 4. PMID: 30263850

Article Published Date : Jul 31, 2018

Study Type : Animal Study

Additional Links

Substances : Ginseng (Korean), Kudzu

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents

Additional Keywords : Natural Substance Synergy

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A Ginkgo biloba and ginsenoside Rg3 extract possesses significant protective activities against ADHD-like conditions.Feb 28, 2014

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Pubmed Data : Food Chem Toxicol. 2014 Mar ;65:280-92. Epub 2014 Jan 3. PMID: 24394491

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Pubmed Data : J Exp Clin Cancer Res. 2016 Feb 13 ;35:32. Epub 2016 Feb 13. PMID: 26872471

Article Published Date : Feb 12, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Glioblastoma

Pharmacological Actions : Anti-Angiogenic, Antiproliferative , Cell cycle arrest

Additional Keywords : Natural Substance/Drug Synergy

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Pubmed Data : Sci Rep. 2017 Jan 20 ;7:41144. Epub 2017 Jan 20. PMID: 28106137

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Pubmed Data : J Ginseng Res. 2016 Jul ;40(3):237-44. Epub 2015 Aug 12. PMID: 27616899

Article Published Date : Jun 30, 2016

Study Type : Animal Study

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Substances : Ginseng (Korean)

Diseases : Hypertension

Pharmacological Actions : Antihypertensive Agents

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An extract of black ginseng ameliorated hypercholesterolemia in rats fed a high-cholesterol diet.Mar 31, 2016

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Pubmed Data : J Ginseng Res. 2016 Apr ;40(2):160-8. Epub 2015 Jul 18. PMID: 27158237

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Pubmed Data : Planta Med. 1991 Dec ;57(6):523-6. PMID: 1818342

Article Published Date : Nov 30, 1991

Study Type : Animal Study

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Substances : Ginsenosides

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Hepatoprotective

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Anti-inflammatory activity of Rg3-enriched Korean red ginseng extract in murine model of sepsis.Dec 31, 2017

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Pubmed Data : Behav Med. 2011 Apr ;37(2):42-6. PMID: 21660771

Article Published Date : Mar 31, 2011

Study Type : Animal Study

Additional Links

Substances : Ginseng (Korean), Ginsenosides

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Phytotherapy, Plant Extracts

Problem Substances : Fluoxetine (trade name Prozac)

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Anti‑angiogenic effect of mountain ginseng in vitro and in vivo.Jul 31, 2021

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Pubmed Data : Mol Med Rep. 2021 Aug ;24(2). Epub 2021 Jun 29. PMID: 34225442

Article Published Date : Jul 31, 2021

Study Type : Animal Study, In Vitro Study

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Substances : Ginseng

Diseases : Cancers: All

Pharmacological Actions : Angiogenesis Inhibitors, Anti-Angiogenic

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Antrodia camphorata and Panax ginseng complex could be a potential formulation with an anti-fatigue pharmacological effect.Feb 19, 2018

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Pubmed Data : J Vet Med Sci. 2018 Feb 20 ;80(2):284-291. Epub 2017 Dec 25. PMID: 29276207

Article Published Date : Feb 19, 2018

Study Type : Animal Study

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Substances : Antrodia camphorata, Panax Ginseng

Diseases : Fatigue: Excercise-Induced

Therapeutic Actions : Exercise, Exercise: Swimming

Additional Keywords : Antrodia camphorata, exercise, Exercise: Swimming, Fatigue: Excercise-Induced, Panax Ginseng

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Attenuating effect of Ginsenoside Rb1 on LPS-induced lung injury in rats.Dec 31, 2013

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Pubmed Data : Biol Pharm Bull. 1995 Sep ;18(9):1197-202. PMID: 8845804

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Pubmed Data : J Ginseng Res. 2020 Jul ;44(4):619-626. Epub 2019 Jun 12. PMID: 32617042

Article Published Date : Jun 30, 2020

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Diabetes Mellitus: Type 1: Prevention

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Risk Reduction

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Doxorubicin nanomedicine based on ginsenoside Rg1 with alleviated cardiotoxicity and enhanced antitumor activity.Oct 31, 2021

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Pubmed Data : Nanomedicine (Lond). 2021 Nov 1. Epub 2021 Nov 1. PMID: 34719938

Article Published Date : Oct 31, 2021

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Pubmed Data : J Ginseng Res. 2022 May ;46(3):464-472. Epub 2021 Nov 11. PMID: 35600775

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Pubmed Data : Genet Mol Res. 2017 Mar 30 ;16(1). Epub 2017 Mar 30. PMID: 28362999

Article Published Date : Mar 29, 2017

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Anti-Apoptotic, Hepatoprotective, Hypoglycemic Agents, Hypolipidemic

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Effects of ginsenoside Rg3 on inhibiting differentiation, adipogenesis, and ER stress-mediated cell death in brown adipocytes.Dec 31, 2020

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Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:6668665. Epub 2021 Mar 16. PMID: 33815558

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Pubmed Data : Asian Pac J Trop Med. 2016 Feb ;9(2):180-3. Epub 2016 Jan 11. PMID: 26919952

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Pubmed Data : J Med Food. 2021 Jun ;24(6):569-576. PMID: 34161163

Article Published Date : May 31, 2021

Study Type : Animal Study

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Substances : Fermented Foods and Beverages, Ginseng

Diseases : Allergic Rhinitis, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-4 downregulation

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Fermented red ginseng and ginsenoside Rd alleviate ovalbumin-induced allergic rhinitis.Sep 30, 2019

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Pubmed Data : J Ginseng Res. 2019 Oct ;43(4):635-644. Epub 2019 Mar 7. PMID: 31695569

Article Published Date : Sep 30, 2019

Study Type : Animal Study

Additional Links

Substances : Ginseng (Korean), Ginsenosides

Diseases : Allergic Rhinitis

Pharmacological Actions : interleukin-13 down-regulation, Interleukin-4 downregulation, Interleukin-5 downregulation

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Fermented red ginseng might be a beneficial therapeutic approach for metabolic syndrome.Jun 15, 2016

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Pubmed Data : Biol Trace Elem Res. 2017 Jun ;177(2):331-344. Epub 2016 Nov 16. PMID: 27854046

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Pubmed Data : Nutrients. 2017 Aug 24 ;9(9). Epub 2017 Aug 24. PMID: 28837087

Article Published Date : Aug 23, 2017

Study Type : Animal Study

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Substances : Ginseng

Diseases : Alcohol Toxicity , Depression

Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator

Additional Keywords : Plant Extracts

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Ginseng extract reduces bacterial load and lung pathology in chronic P. aeruginosa pneumonia in rats.May 01, 1997

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Pubmed Data : Antimicrob Agents Chemother. 1997 May;41(5):961-4. PMID: 9145852

Article Published Date : May 01, 1997

Study Type : Animal Study

Additional Links

Substances : Ginseng (Asian)

Diseases : Pneumonia, Pseudomonas aeruginosa

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Ginseng extract reduces tacrolimus-induced oxidative stress by modulating autophagy in pancreatic beta cells.Jul 30, 2017

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Pubmed Data : Lab Invest. 2017 Jul 31. Epub 2017 Jul 31. PMID: 28759009

Article Published Date : Jul 30, 2017

Study Type : Animal Study

Additional Links

Substances : Ginseng (Korean)

Diseases : Mitochondrial Dysfunction , Oxidative Stress

Pharmacological Actions : Antioxidants, Pancreato Protective Agents

Problem Substances : Tacrolimus

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Ginseng extracts may suppress the cognitive decline associated with aging.Sep 30, 2017

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Pubmed Data : Nutrients. 2016 Dec 13 ;8(12). Epub 2016 Dec 13. PMID: 27983571

Article Published Date : Dec 12, 2016

Study Type : Animal Study

Additional Links

Substances : Ginsenosides, Panax Ginseng

Diseases : Fatigue: Excercise-Induced

Pharmacological Actions : Antioxidants

Additional Keywords : Antioxidants, Fatigue: Excercise-Induced, Ginsenosides, Panax Ginseng, Polysaccharides

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Ginseng polysaccharide could effectively prevent cisplatin-induced ER stress, inflammation, and apoptosis in renal cells.Apr 05, 2021

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Pubmed Data : ACS Omega. 2021 Apr 6 ;6(13):8958-8966. Epub 2021 Mar 24. PMID: 33842766

Article Published Date : Apr 05, 2021

Study Type : Animal Study

Additional Links

Substances : Ginseng

Diseases : Chemotherapy-Induced Kidney Damage, Chemotherapy-Induced Toxicity: Cisplatin

Pharmacological Actions : Chemoprotective Agents, Renoprotective

Additional Keywords : Polysaccharides

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Ginseng reduces neurologic damage in subarachanoid hemorrhage. Mar 31, 2010

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Pubmed Data : Cancer Lett. 1991 May 1;57(2):91-4. PMID: 9236860

Article Published Date : May 01, 1991

Study Type : Animal Study

Additional Links

Substances : Ginseng, unspecified species

Diseases : Pseudomonas aeruginosa

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Ginseng was protective against RSV infection through multiple mechanisms, which include improving cell survival, partial inhibition of viral replication and modulation of cytokines. Dec 31, 2014

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Pubmed Data : Nutrients. 2015 ;7(2):1021-36. Epub 2015 Feb 4. PMID: 25658239

Article Published Date : Dec 31, 2014

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Panax Ginseng

Diseases : Respiratory Syncytial Virus Infections

Pharmacological Actions : Anti-Inflammatory Agents, Antiviral Agents

Additional Keywords : Dose Response

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Ginsenoside 20(S)-protopanaxadiol attenuates depressive-like behaviour and neuroinflammation in chronic unpredictable mild stress.May 24, 2020

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Pubmed Data : Behav Brain Res. 2020 May 25:112710. Epub 2020 May 25. PMID: 32464121

Article Published Date : May 24, 2020

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Brain Inflammation , Depression

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antidepressive Agents

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Ginsenoside 20(S)-Rg3 inhibited the Warburg effect in ovarian cancer cells via H19/miR-324-5p/PKM2 pathway.Dec 31, 2017

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Pubmed Data : Cell Physiol Biochem. 2018 ;51(3):1340-1353. Epub 2018 Nov 27. PMID: 30481782

The Following are Sub-Topics of Ginseng

View the Evidence: 1440 Abstracts with Ginseng Research

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Exploratory systematic review and meta-analysis of Panax genus plant ingestion evaluation in exercise endurance.Mar 10, 2022

Ginseng supplementation may be an effective strategy for improving cardiometabolic profiles in individuals with prediabetes and T2DM.Jun 08, 2022

A meta-analysis of ginsenoside Rg3 combined with chemotherapy for digestive system cancer in China.Dec 31, 2018

Available findings demonstrated the preclinical evidence that Ginsenoside-Rb1 has a potential neuroprotective effects.Dec 31, 2019

Effect of ginsenoside-Rg1 on experimental Parkinson's disease.May 31, 2021

Ginsenoside Rg3 for chemotherapy-induced myelosuppression.Dec 31, 2019

Panax ginseng extract may induce an improvement in blood lipid profile mainly by a reduction in total and LDL-cholesterol levels.Jul 13, 2019

The effect of ginsenosides on depression in preclinical studies.Apr 30, 2021

The efficacy of ginsenoside Rg3 combined with first-line chemotherapy in the treatment of advanced non-small cell lung cancer. Dec 31, 2019

This review provides positive evidence for the efficacy of ginseng on reducing blood pressure in patients with pre-hypertension and hypertension.Jul 11, 2017

The combination of omega-3 and Korean red ginseng may have beneficial effects in children with subthreshold ADHD.Aug 25, 2020

"North American ginseng extract, improves working memory in schizophrenia." Dec 30, 2011

Acute effects of combined Bacopa, American ginseng and whole coffee fruit on working memory and cerebral haemodynamic response of the prefrontal cortex.Nov 17, 2019

AGM possibly improves insulin sensitivity and β-cell function and reduces liver damage and inflammation in prediabetic adults.Jul 04, 2021

American Ginseng (in combination with Ginkgo biloba) impoves symptoms of ADHD.May 01, 2001

American ginseng (Panax quinquefolius L.) has a positive effect on glycemic control in type 2 diabetes.Nov 30, 2012

American ginseng extract added to conventional treatment provided an effective and safe adjunct in the management of T2DM.Feb 23, 2018

American Ginseng has a neutral effect on blood pressure in hypertensive individuals.Aug 01, 2005

American Ginseng has no effect on 24-hour blood pressure and renal function in hypertensive individuals. Apr 01, 2006

American ginseng has radioprotective effect on human lymphocytes at 90 minutes postirradiation.May 01, 2010

American Ginseng is safe and effective in reducing relative risk and duration of respiratory symptoms associated with "cold and flu" in adults. Mar 01, 2006

American ginseng is safe, well tolerated, and potentially effective for preventing acute respiratory illness due to influenza and respiractory syncytial virus infections.Jan 01, 2004

American ginseng reduces high blood sugar after meals in both diabetic and nondiabetic subjects. Apr 10, 2000

American ginseng reduces oxidative stress in patients taking the antiviral medication zidovudine without altering drug pharmacokinetics. May 01, 2008

American ginseng tea protects cellular DNA within 2 h from consumption.Dec 31, 2014

An enzyme-modified ginseng extract treatment for 4 weeks decreased fatigue severity in a healthy population.Oct 31, 2016

An herbal extract combination (Biochanin A, Acetyl tetrapeptide-3, and ginseng extracts) versus 3% minoxidil solution for the treatment of androgenetic alopecia.Sep 30, 2020

Beneficial effect of Korean red ginseng on plasma ceramide levels in postmenopausal women with hypercholesterolemia.Jun 23, 2021

Both hydroponically cultivated red and wild growing white ginseng have similar beneficial effects on the cognitive functions of elderly subjects.Feb 24, 2021

Daily supplementation of Korean Red Ginseng for 8 weeks significantly improved the TBUT score and subjective dry eye symptoms, as compared to placebo.Dec 31, 2014

Daily supplementation with fermented red ginseng lowered postprandial glucose levels in subjects with impaired fasting glucose or type 2 diabetes.Jul 10, 2014

Echinacea purpurea and Panax ginseng enhance cellular immune function of peripheral blood mononuclear cells both from normal individuals and patients with depressed cellular immunity.Jan 01, 1997

Effect of ginseng extracts on the improvement of osteopathic and arthritis symptoms in women with osteopenia.Sep 23, 2021

Effect of Korea red ginseng on nonalcoholic fatty liver disease.Feb 28, 2021

Enzyme-treated red ginseng extract significantly improved eye wrinkle roughness, skin elasticity, and moisture content of skin. Jun 30, 2016

Ginsan significantly enhanced natural killer (NK) cell cytotoxic activity by 40% after administration for 14 weeks.Dec 31, 2013

Ginseng could improve glucose control and insulin sensitivity in patients with T2DM or impaired glucose intolerance.Jan 31, 2016

Ginseng extract improves quality of life and physiological symptoms of postmenopausal women. Jan 01, 1999

Ginseng improves pulmonary function and exercise capacity in patients with COPD. Nov 01, 2009

Ginseng improves the condition of patients with congestive heart failure and raises levels of T3 and T4. Apr 01, 1999

Ginsenoside Rb1 treatment was effective in reducing the extent of oxidative stress and inflammation in chronic kidney disease patients.Jan 31, 2017

Ginsenoside Rd is efficacious against acute ischemic stroke.Apr 30, 2016

Ginsenoside Rg3 could be used as a new regimen to delay acquired resistance of epidermal growth factor receptor-tyrosine kinase inhibitors.Oct 24, 2016

Ginsenoside Rg3 inhibits HIF-1α and VEGF expression in patients with acute leukemia.Dec 31, 2013

Ginsenoside-Rd improves outcome of acute ischaemic stroke.May 31, 2012

Ginsenoside-Rd may be of some benefit in acute ischaemic stroke.Apr 30, 2009

High-dose ginsenoside supplementation augmented the improvement of aerobic capacity by exercise training.Mar 31, 2018

Immuno-enhancement effects of Korean red ginseng in healthy adults.Dec 31, 2020

In this preliminary study korean red ginseng significantly lowered the incidences of acute respiratory infections. Nov 30, 2012

Korea red ginseng has therapeutic activity in treating Helicobacter pylori-induced halitosis:Jan 01, 2009

Korean ginseng improves treatment outcomes in HIV-infected patients on antiretroviral therapy. Aug 01, 2009

Korean red ginseng can be safely used as a health food to achieve clinical improvement of atopic dermatitis as well as improving overall quality of life.May 31, 2018

Korean Red Ginseng contain compounds which improve arterial stiffness in healthy individuals. Feb 04, 2010

Korean Red Ginseng could be used as a complementary therapy for chronic hepatitis B.Nov 30, 2016

Korean red ginseng for cancer-related fatigue in colorectal cancer patients with chemotherapy.Apr 30, 2020

Korean red ginseng lowers urinary BPA levels and BPA-induced malondialdehyde levels and alleviates gynecological complaints without side effects of raw-ginseng.Dec 31, 2013

Korean red ginseng may be a useful agent for the treatment of male infertility.Jun 30, 2016

Korean red ginseng may improve tinnitus symptoms and mental wellbeing in chronic tinnitus patients.Aug 31, 2015

Korean red ginseng might be effective in reducing pro-inflammatory cytokines and fatigue in overweight patients with NAFLD.Jun 30, 2016

Korean red ginseng might help to stabilize the sympathetic nervous system and improve cognition in individuals with high stress.Jun 30, 2019

Korean red ginseng prolongs survival in HIV-1 patients, possibly by slowing the decrease in CD4+ T-cell count.Mar 31, 2017

Korean red ginseng supplementation may attenuate lymphocyte DNA damage and LDL oxidation by upregulating antioxidant enzyme activity.Jul 16, 2012

Panax ginseng improves symptoms in men with erectile dysfunction. May 01, 2009

Panax ginseng is safe and improves cancer-related fatigue as well as overall quality of life, appetite, and sleep at night.Aug 31, 2015

Protective effect of Korean red ginseng on oxaliplatin-mediated splenomegaly in colon cancer.Aug 31, 2018

Protective effects of ginsenoside on myocardiac ischemic and reperfusion injuries.Sep 30, 1994

Red ginseng extract containing panaxynol and panaxydol can effectively control the symptoms of acne.Feb 28, 2019

Red ginseng root extract mixed with Torilus fructus and Corni fructus improves facial wrinkles and increases type I procollagen synthesis in human skin.Dec 01, 2009

The combination of transcatheter arterial chemoembolization and ginsenoside Rg3 may prolong overall survival when compared with it alone.Jul 31, 2016

The present study confirms the safety and tolerability of daily intake of 2g of Korean red ginseng for 24 weeks by healthy adults.Sep 30, 2018

These results suggest a potential role for ginseng in modulating salivary androgen levels.May 27, 2020

This data suggested that consumers on a Western diet should obtain better cancer prevention effects with American ginseng intake.Mar 31, 2017

Ginseng

View the Evidence:
1440 Abstracts with Ginseng Research