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Ginsenosides
Views 3393
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277 Diseases Researched for Ginsenosides
Name
AC
CK
Focus
Oxidative Stress
38
72
Liver Cancer
35
71
Alzheimer's Disease
42
66
Lung Cancer
37
56
Inflammation
37
51
Stroke: Ischemic
8
47
Colorectal Cancer
16
45
Lipopolysaccharide-Induced Toxicity
30
44
Depression
21
41
Obesity
25
41
Myocardial Ischemia
19
40
Carcinoma: Non-Small-Cell Lung
8
37
Cancers: All
23
35
Breast Cancer
29
34
Parkinson's Disease
11
32
Gastric Cancer
9
28
Cognitive Decline/Dysfunction
14
26
Brain Ischemia
9
25
Memory Disorders
13
25
Pancreatic Cancer
4
25
Cancers: Drug Resistant
14
24
Esophageal Cancer
4
24
Cerebral Ischemia
14
23
Chemotherapy-Induced Toxicity: Cisplatin
13
23
Diabetes Mellitus: Type 2
16
23
Chemically-Induced Liver Damage
12
22
Ovarian Cancer
16
21
Brain Inflammation
12
20
Chemotherapy Induced Myelotoxicity
1
20
Diabetic Complications
11
20
High Fat Diet
10
20
Aging: Brain
5
18
Nonalcoholic fatty liver disease (NAFLD)
10
18
Melanoma
12
17
Stroke
5
17
Acetaminophen (Tylenol) Toxicity
8
15
Atherosclerosis
10
15
DNA damage
5
15
Leukemia: Acute myelogenous leukemia (AML)
5
15
Spinal Cord Injuries
9
15
Cardiovascular Diseases
11
14
Colon Cancer
12
14
Diabetes Mellitus: Type 1
7
14
HIV Infections
4
14
Hypoxia
10
14
Insulin Resistance
9
14
Chronic Kidney Disease (CKD)
3
13
Hydrogen Peroxide Induced Toxicity
11
13
Osteoarthritis
6
13
Wound Healing
7
13
Athletic Performance
2
12
Cancer Metastasis
11
12
Myocardial Infarction
7
12
Sepsis
8
12
Aging Skin
2
11
Chemotherapy-Induced Toxicity: Cyclophosphamide
7
11
Liver Fibrosis
6
11
Radiation Induced Illness
2
11
Breast Cancer: Triple Negative
8
10
Dry Eye Syndromes
1
10
Neurodegenerative Diseases
8
10
Testosterone: Too High
1
10
Aging
5
9
Chemotherapy-Induced Toxicity: Doxorubicin
6
9
Diabetic Retinopathy
5
9
Endometriosis
5
9
Hair Loss
4
9
Colitis
4
8
Diabetic Nephropathy
4
8
Glioblastoma
5
8
Ischemia
5
8
Leukemia
7
8
Prostate Cancer
8
8
Air Pollution Linked Toxicity
2
7
Atopic Dermatitis
5
7
Hypertension
4
7
Lipid Peroxidation
4
7
Lung Injury: Acute
4
7
Lung Injury: Smoke-Induced
4
7
Osteoporosis
5
7
Psoriasis
4
7
Skin Cancer
6
7
Squamous cell carcinoma
6
7
Ultraviolet Radiation Induced Damage
6
7
Alcoholic Liver Disease
3
6
Arthritis
3
6
Brain: Microglial Activation
5
6
Cardiac Hypertrophy
3
6
Cervical Cancer
6
6
Fatigue
3
6
Hypertension: Pulmonary
3
6
Inflammatory Bowel Diseases
4
6
Liver Damage
4
6
Memory Disorders: Drug-Induced
3
6
Osteosarcoma
6
6
Ovarian Failure
3
6
Dementia
3
5
Dermatitis
3
5
Erectile Dysfunction
3
5
Heart Failure
3
5
Huntington Disease
3
5
Hyperglycemia
4
5
Learning disorders
3
5
Myocardial Fibrosis
3
5
Scars
3
5
Stroke: Attenuation/Recovery
3
5
Anxiety
2
4
Autoimmune Diseases
3
4
Burns
2
4
Cardiomyopathy
2
4
Chronic Obstructive Pulmonary Disease
2
4
Diabetes: Cardiovascular Illness
2
4
Diabetes: Cognitive Dysfunction
2
4
Diabetes: Oxidative Stress
2
4
Fatigue: Excercise-Induced
2
4
Glioma
4
4
Hepatic Steatosis
2
4
Hyperlipidemia
2
4
Intestinal Ischemia
2
4
Liver Failure: Acute
2
4
Muscle Atrophy
3
4
Nasopharyngeal Cancer
4
4
Neuroblastoma
3
4
Sleep Disorders
2
4
Staphylococcus aureus infection
2
4
Stress
2
4
Acute Myeloid Leukemia
3
3
Allergic Rhinitis
2
3
Aluminum Toxicity
2
3
Cancers: Multi-Drug Resistant
2
3
Cataract
2
3
Endothelial Dysfunction
2
3
Gallbladder Cancer
2
3
Hearing Loss: Noise-Induced
2
3
Kidney Fibrosis
2
3
Liver Cirrhosis
2
3
Metabolic Diseases
2
3
Multiple Myeloma
3
3
Promyelocytic leukemia
3
3
Rheumatoid Arthritis
2
3
Tertiary butyl hydroperoxide toxicity
2
3
Thyroid Cancer
2
3
Acute T cell Leukemias
2
2
Adiponectin: Low Levels
1
2
Allergies
2
2
Anemia
1
2
Anemia: Iron Deficiency
1
2
Aneurysm: Aortic
1
2
Anti-Glomerular Basement Membrane Disease
1
2
Asthma
2
2
Attention Deficit Disorder with Hyperactivity
1
2
Brain: Oxidative Stress
1
2
Cancer: Pain
1
2
Cerebral Aneurysm
1
2
Chemobrain
1
2
Chemotherapy-Induced Kidney Damage
1
2
Chemotherapy-Induced Neurotoxicity
1
2
Chemotherapy-Induced Toxicity: 5-fluorouracil
1
2
Chemotherapy-Induced Toxicity: Bleomycin
1
2
Chronic Pain
1
2
Coxsackievirus Infections
2
2
Degenerative Disk Disease
2
2
Depression
1
2
Diabetes Mellitus: Type 1: Prevention
1
2
Diabetic Ulcer
1
2
Drug Toxicity: Cephaloridine
1
2
Dysmenorrhea
1
2
Encephalomyelitis
1
2
Encephalopathy
1
2
Endometrial Cancer
2
2
Epilepsy
1
2
Exercise-Induced Tissue Damage
1
2
Fatigue: Cancer-Associated
1
2
Fatty Liver
1
2
Gastric Ulcer
1
2
H1N1 Infection
1
2
Hashimoto's thyroiditis
1
2
Herbicide Toxicity
1
2
High Sugar Diet
1
2
Hypercapnia
1
2
Hypoglycemia
1
2
Influenza A
1
2
Ischemia: Myocardial
1
2
Itching
1
2
Kawasaki Disease
1
2
Keloid
1
2
Kidney Damage
1
2
Kidney Failure: Acute
1
2
Liver Damage: Drug-Induced
1
2
Low Libido
1
2
Low Testosterone
1
2
Mastitis
1
2
Middle Cerebral Artery Occlusion (MCAO)
1
2
Mitochondrial Diseases
2
2
Morphine Tolerance/Dependence
1
2
Multiple Sclerosis
1
2
Nerve Injuries
1
2
Obstructive Nephropathy
1
2
Oral Cancer
1
2
Pain
1
2
Postoperative Recovery
1
2
Pulmonary Fibrosis: Bleomycin-Induced
1
2
Right Ventricular Hypertrophy
1
2
Rotavirus Infections
1
2
Sciatic Nerve Crush Injury
1
2
Sciatica
1
2
Smoking: Pulmonary
1
2
Subarachnoid hemorrhage
1
2
Ulcerative Colitis
1
2
Acute lymphoblastic leukemia (ALL)
1
1
Aging: Heart
1
1
Alcohol Toxicity
1
1
Alopecia
1
1
Amyotrophic lateral sclerosis (ALS)
1
1
Benzo[a]pyrene-induced Toxicity
1
1
Bladder Cancer
1
1
Bone Diseases
1
1
Brain Hypoxia
1
1
Brain Injury: Hippocampal Damage
1
1
Brain Injury: Traumatic
1
1
Central Nervous System Diseases
1
1
Cholesterol: Oxidation
1
1
Demyelinating Diseases
1
1
Dental Caries
1
1
Dyslipidemias
1
1
Endothelial Damage
1
1
Enterovirus 71
1
1
Enterovirus: Type 71
1
1
Escherichia coli Infections
1
1
Fibroma: Uterine
1
1
Fibrosarcoma
1
1
Fibrosis
1
1
Gastrointestinal Cancer
1
1
Gastrointestinal polyps
1
1
Glioblastoma Multiforme
1
1
Heart Disease: Ischemic
1
1
Hepatitis A
1
1
Hepatitis B
1
1
Hepatitis C
1
1
Herpes Simplex Virus Type 1
1
1
Herpes Simplex Virus Type 2
1
1
Histamine: Elevated
1
1
Homocysteine: Elevated
1
1
Hyperhomocysteinemia
1
1
Immune Dysregulation: TH1 dominance
1
1
Immune Dysregulation: TH1/TH2 imbalance
1
1
Kidney Damage: Chemically-Induced
1
1
Kidney Failure
1
1
Lead Poisoning
1
1
Leukemia: Acute promyelocytic leukemia
1
1
Leukemia: Chronic myelogenous leukemia (CML)
1
1
Leukemia: Multi-Drug Resistant
1
1
Leukemia: T-cell acute Lymphoblastic
1
1
Liver Disease
1
1
Liver Injury: Ischemia/reperfusion
1
1
Liver Steatosis
1
1
Medulloblastoma
1
1
Mitochondrial Dysfunction
1
1
Non-Small-Cell Lung Carcinoma
1
1
Parasitic Diseases
1
1
Pesticide Toxicity
1
1
Prion Diseases
1
1
Prostatic Hyperplasia: Benign
1
1
Pruritus
1
1
Radiation-Induced Illness: Cesium-137 Exposure
1
1
Rectal Cancer
1
1
Retinal Diseases
1
1
Retinoblastoma
1
1
Rhinovirus Infection
1
1
Scars: Hyperplastic
1
1
Schizophrenia
1
1
Schwannoma: Vestibular
1
1
Sperm Quality: Low
1
1
Steptococcus Mutans Infections
1
1
Surgery: Anesthesiology
1
1
Tachycardia
1
1
Vascular Calcification
1
1
137 Pharmacological Actions Researched for Ginsenosides
Name
AC
CK
Focus
Anti-Inflammatory Agents
160
303
Neuroprotective Agents
139
298
Antioxidants
114
234
Antiproliferative
135
184
Apoptotic
138
160
Anti-Apoptotic
77
139
Tumor Necrosis Factor (TNF) Alpha Inhibitor
68
113
Cardioprotective
64
107
Interleukin-1 beta downregulation
53
94
Chemotherapeutic
42
90
Anti-metastatic
53
88
Hepatoprotective
49
85
Chemoprotective Agents
27
82
NF-kappaB Inhibitor
51
81
Interleukin-6 Downregulation
41
77
Angiogenesis Inhibitors
18
63
Immunomodulatory
29
59
Chemosensitizer
20
47
Antidepressive Agents
20
39
Antineoplastic Agents
30
35
Matrix metalloproteinase-2 (MMP-2) inhibitor
24
35
Cyclooxygenase 2 Inhibitors
21
34
Vascular Endothelial Growth Factor Inhibitors
18
34
Cell cycle arrest
29
33
Nrf2 activation
21
33
Malondialdehyde Down-regulation
17
32
Matrix metalloproteinase-9 (MMP-9) inhibitor
17
29
Renoprotective
13
28
MicroRNA modulator
20
27
Chemopreventive
12
24
Hypoglycemic Agents
14
24
Anti-Fibrotic
14
23
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
12
23
Superoxide Dismutase Up-regulation
12
22
Neurogenesis
1
20
Anti-Angiogenic
7
19
Autophagy Up-regulation
13
18
Brain-derived neurotrophic factor modulator
8
16
Hypolipidemic
9
16
Bcl-2 protein down-regulation
12
14
Gastrointestinal Agents
8
14
Radioprotective
4
14
Tumor Suppressor Protein p53 Upregulation
12
14
Interleukin-18 down-regulation
6
12
Anti-HIV Agents
2
11
Cytoprotective
6
11
Heme oxygenase-1 up-regulation
6
11
Pancreato Protective Agents
5
11
HIV Protease Inhibitors
1
10
Antiviral Agents
7
9
Autophagy Inhibitors
6
9
Osteoprotective
5
8
Angiogenesis Inducing Agents
4
7
Antihypertensive Agents
4
7
Chondroprotective
2
7
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
3
7
Nitric Oxide Inhibitor
5
7
Photoprotective
6
7
Transforming growth factor beta (TGF-β) inhibitor
5
7
Wnt/β-catenin signaling pathway modulation
6
7
Analgesics
3
6
Anti-atherogenic
3
6
Antinoceceptive
3
6
Gastroprotective
3
6
Histone deacetylase inhibitor
4
6
Interleukin-4 downregulation
4
6
Matrix metalloproteinase-1 (MMP-1) inhibitor
2
6
Anticarcinogenic Agents
3
5
Interferon Gamma Reducer
3
5
Prophylactic Agents
3
5
Prostaglandin PGE2 downregulation
1
5
SIRT1 Activator
3
5
Enzyme Inhibitors
3
4
Interleukin-8 downregulation
3
4
Neuritogenic
3
4
Radiosensitizer
3
4
Vasodilator Agents
2
4
Anti-Bacterial Agents
2
3
Heat Shock Protein Down-Regulation
2
3
Immunomodulatory: Th17 downregulation
2
3
Immunostimulatory
3
3
Insulin Sensitizers
2
3
Adiponectin upregulation
1
2
Anti-Adipogenic
1
2
Anti-Anxiety Agents
1
2
Anti-Platelet
1
2
Anti-Ulcer Agents
1
2
Anticholesteremic Agents
1
2
Anticoagulants
1
2
Anticonvulsants
1
2
Antimicrobial
2
2
Antipruritics
1
2
Aphrodisiac
1
2
DNA Repair Up-regulation
2
2
E-cadherin down-regulation
1
2
Epidermal growth factor receptor (EGFR) inhibitor
1
2
Fertility Agents: Female
1
2
GABA Modulators
1
2
Genoprotective
1
2
Heme oxygenase-1 inducer
2
2
Interleukin-10 downregulation
1
2
Interleukin-17 downregulation
1
2
Interleukin-22 Downregulation
1
2
Interleukin-23 Downregulation
1
2
Interleukin-5 downregulation
1
2
Matrix Metalloproteinase-7 (MMP-7) Inhibitor
2
2
Multidrug Resistance Gene Modulators
1
2
Nitric Oxide Enhancer
1
2
Postaglandin PGE2 downregulation
1
2
Regenerative
1
2
STAT3 Inhibitor
1
2
Secretagogue
1
2
Telomerase Inhibitor
2
2
Vascular Endothelial Growth Factor A Inhibitor
1
2
Vascular Endothelial Growth Factor C Inhibitor
1
2
Vascular Endothelial Growth Factor Regulator
2
2
Viral Hemagglutinin Inhibitor
1
2
interleukin-13 down-regulation
1
2
Acetylcholinesterase Down-Regulation
1
1
Anti-Retroviral Agents
1
1
Antiparasitic Agents
1
1
Cyclin D1 Down-Regulation
1
1
Fertility Agents: Male
1
1
Glucagon Like peptide 1 (GLP-1) Up-regulation
1
1
Histamine down-regulation
1
1
Insulin-Like Growth Factor Enhancer/Upregulation
1
1
Interleukin-1 alpha downregulation
1
1
Interleukin-10 upregulation
1
1
Interleukin-12 downregulation
1
1
Interleukin-2 upregulation
1
1
Osteogenic
1
1
P21 Activation
1
1
Paraptosis
1
1
Survivin Down-Regulation
1
1
Transforming growth factor beta (TGF-β) upregulation
1
1
Vascular Endothelial Growth Factor A Enhancer
1
1
Vasoprotective
1
1
Research Articles
873
Cumulative Knowledge Score
1412
Overall Research Rating
EXCELLENT
Related Topics
Ginsenosides is a Sub of the following Topic
Ginseng
View the Evidence:
1304 Abstracts with Ginsenosides Research
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[+]
Exploratory systematic review and meta-analysis of Panax genus plant ingestion evaluation in exercise endurance.
Mar 10, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2022 Mar 11 ;14(6). Epub 2022 Mar 11. PMID:
35334841
Article Published Date
: Mar 10, 2022
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Athletic Performance
Therapeutic Actions
:
Exercise
[+]
Ginsenoside can protect against the renal failure in diabetes.
Oct 28, 2022
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2022 Oct 29 ;302(Pt A):115860. Epub 2022 Oct 29. PMID:
36341813
Article Published Date
: Oct 28, 2022
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The effect of ginsenoside Rg3 combined with chemotherapy on immune function in non-small cell lung cancer.
Apr 06, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Medicine (Baltimore). 2023 Apr 7 ;102(14):e33463. PMID:
37026927
Article Published Date
: Apr 06, 2023
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Carcinoma: Non-Small-Cell Lung
,
Lung Cancer
Pharmacological Actions
:
Chemotherapeutic
,
Immunomodulatory
[+]
The effect of ginsenosides on liver injury.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2023 ;14:1184774. Epub 2023 May 11. PMID:
37251340
Article Published Date
: Dec 31, 2022
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
A meta-analysis of ginsenoside Rg3 combined with chemotherapy for digestive system cancer in China.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2019 ;2019:2417418. Epub 2019 Dec 17. PMID:
31929811
Article Published Date
: Dec 31, 2018
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colorectal Cancer
,
Esophageal Cancer
,
Gastric Cancer
,
Liver Cancer
,
Pancreatic Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Antiproliferative
,
Chemotherapeutic
[+]
Available findings demonstrated the preclinical evidence that Ginsenoside-Rb1 has a potential neuroprotective effects.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2020 ;11:285. Epub 2020 Mar 31. PMID:
32296332
Article Published Date
: Dec 31, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Neurogenesis
,
Neuroprotective Agents
[+]
Effect of ginsenoside-Rg1 on experimental Parkinson's disease.
May 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2021 Jun ;21(6):552. Epub 2021 Mar 25. PMID:
33850524
Article Published Date
: May 31, 2021
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rg3 for chemotherapy-induced myelosuppression.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2020 ;11:649. Epub 2020 May 12. PMID:
32477128
Article Published Date
: Dec 31, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy Induced Myelotoxicity
Pharmacological Actions
:
Chemoprotective Agents
,
Immunomodulatory
[+]
The effect of ginsenosides on depression in preclinical studies.
Apr 30, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2021 May ;45(3):420-432. Epub 2020 Sep 4. PMID:
34025135
Article Published Date
: Apr 30, 2021
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
[+]
The efficacy of ginsenoside Rg3 combined with first-line chemotherapy in the treatment of advanced non-small cell lung cancer.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2020 ;11:630825. Epub 2021 Mar 18. PMID:
33815097
Article Published Date
: Dec 31, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Carcinoma: Non-Small-Cell Lung
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Chemoprotective Agents
,
Chemosensitizer
[+]
American ginseng has radioprotective effect on human lymphocytes at 90 minutes postirradiation.
May 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Altern Complement Med. 2010 May;16(5):561-7. PMID:
20491513
Article Published Date
: May 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Ginseng (American)
,
Ginsenosides
Diseases
:
DNA damage
,
Oxidative Stress
,
Radiation Induced Illness
Pharmacological Actions
:
Antioxidants
,
Radioprotective
Additional Keywords
:
Plant Extracts
[+]
American ginseng reduces oxidative stress in patients taking the antiviral medication zidovudine without altering drug pharmacokinetics.
May 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Clin Pharmacol. 2008 May;48(5):599-609. Epub 2008 Mar 4. PMID:
18319359
Article Published Date
: May 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Ginseng (American)
,
Ginsenosides
Diseases
:
HIV Infections
Pharmacological Actions
:
Anti-HIV Agents
,
Antioxidants
,
HIV Protease Inhibitors
Additional Keywords
:
Drug: Zidovudine
,
Plant Extracts
[+]
Both hydroponically cultivated red and wild growing white ginseng have similar beneficial effects on the cognitive functions of elderly subjects.
Feb 24, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmaceuticals (Basel). 2021 Feb 25 ;14(3). Epub 2021 Feb 25. PMID:
33668699
Article Published Date
: Feb 24, 2021
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Aging: Brain
Pharmacological Actions
:
Neuroprotective Agents
[+]
Daily supplementation of Korean Red Ginseng for 8 weeks significantly improved the TBUT score and subjective dry eye symptoms, as compared to placebo.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2015 Jan ;39(1):7-13. Epub 2014 Jul 23. PMID:
25535471
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Dry Eye Syndromes
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Significant Treatment Outcome
,
Supplementation
[+]
Effect of ginseng extracts on the improvement of osteopathic and arthritis symptoms in women with osteopenia.
Sep 23, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2021 Sep 24 ;13(10). Epub 2021 Sep 24. PMID:
34684351
Article Published Date
: Sep 23, 2021
Study Type
: Human Study
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Osteopenia
Pharmacological Actions
:
Osteoprotective
[+]
Enzyme-treated red ginseng extract significantly improved eye wrinkle roughness, skin elasticity, and moisture content of skin.
Jun 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2016 Jul ;40(3):260-8. Epub 2015 Aug 31. PMID:
27616902
Article Published Date
: Jun 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Aging Skin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Ginsenoside Rb1 treatment was effective in reducing the extent of oxidative stress and inflammation in chronic kidney disease patients.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2017 Feb ;25(1):33-40. Epub 2016 Nov 17. PMID:
27853891
Article Published Date
: Jan 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chronic Kidney Disease (CKD)
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Renoprotective
[+]
Ginsenoside Rd is efficacious against acute ischemic stroke.
Apr 30, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Neurobiol. 2016 May ;53(4):2529-40. Epub 2015 Jun 17. PMID:
26081140
Article Published Date
: Apr 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Ginsenoside Rg3 could be used as a new regimen to delay acquired resistance of epidermal growth factor receptor-tyrosine kinase inhibitors.
Oct 24, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Oct 25 ;7(43):70535-70545. PMID:
27655708
Article Published Date
: Oct 24, 2016
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cancers: Drug Resistant
,
Carcinoma: Non-Small-Cell Lung
,
Lung Cancer
Pharmacological Actions
:
Chemotherapeutic
[+]
Ginsenoside Rg3 inhibits HIF-1α and VEGF expression in patients with acute leukemia.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Clin Exp Pathol. 2014 ;7(5):2172-8. Epub 2014 Apr 15. PMID:
24966925
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Leukemia: Acute myelogenous leukemia (AML)
Pharmacological Actions
:
Anti-Angiogenic
,
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Ginsenoside-Rd improves outcome of acute ischaemic stroke.
May 31, 2012
Click here to read the entire abstract
Pubmed Data
: Eur J Neurol. 2012 Jun ;19(6):855-63. Epub 2012 Jan 10. PMID:
22233205
Article Published Date
: May 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside-Rd may be of some benefit in acute ischaemic stroke.
Apr 30, 2009
Click here to read the entire abstract
Pubmed Data
: Eur J Neurol. 2009 May ;16(5):569-75. Epub 2009 Feb 19. PMID:
19236467
Article Published Date
: Apr 30, 2009
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Ischemia
,
Stroke
Pharmacological Actions
:
Neuroprotective Agents
[+]
High-dose ginsenoside supplementation augmented the improvement of aerobic capacity by exercise training.
Mar 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2018 Apr ;42(2):192-198. Epub 2017 Apr 5. PMID:
29719466
Article Published Date
: Mar 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Athletic Performance
Therapeutic Actions
:
Exercise
[+]
Protective effects of ginsenoside on myocardiac ischemic and reperfusion injuries.
Sep 30, 1994
Click here to read the entire abstract
Pubmed Data
: Zhonghua Yi Xue Za Zhi. 1994 Oct ;74(10):626-8, 648. PMID:
7842343
Article Published Date
: Sep 30, 1994
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Cardioprotective
[+]
The combination of transcatheter arterial chemoembolization and ginsenoside Rg3 may prolong overall survival when compared with it alone.
Jul 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Radiology. 2016 Aug ;280(2):630-9. Epub 2016 Feb 17. PMID:
26885681
Article Published Date
: Jul 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Liver Cancer
Pharmacological Actions
:
Chemotherapeutic
[+]
These results suggest a potential role for ginseng in modulating salivary androgen levels.
May 27, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2020 May 28 ;12(6). Epub 2020 May 28. PMID:
32481563
Article Published Date
: May 27, 2020
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Testosterone: Too High
[+]
This data suggested that consumers on a Western diet should obtain better cancer prevention effects with American ginseng intake.
Mar 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Chromatogr. 2017 Apr ;31(4). Epub 2016 Oct 13. PMID:
27606833
Article Published Date
: Mar 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Ginseng (American)
,
Ginsenosides
Diseases
:
Cancers: All
Pharmacological Actions
:
Chemopreventive
[+]
Ginsenoside Rb1 inhibits oxidative stress-induced ovarian granulosa cell injury through Akt-FoxO1 interaction.
Oct 31, 2022
Click here to read the entire abstract
Pubmed Data
: Sci China Life Sci. 2022 Nov ;65(11):2301-2315. Epub 2022 Jun 1. PMID:
35661967
Article Published Date
: Oct 31, 2022
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Ginsenosides
Diseases
:
Ovarian Diseases
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
Cytoprotective effects of ginsenoside Rd on apoptosis-associated cell death in the isolated human pancreatic islets.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: EXCLI J. 2019 ;18:666-676. Epub 2019 Aug 22. PMID:
31611749
Article Published Date
: Dec 31, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 1
Pharmacological Actions
:
Cytoprotective
,
Pancreato Protective Agents
[+]
Ginsenoside 20(S)-Rh2 has therapeutic potential for the treatment with colorectal cancer.
Dec 23, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Dec 24 ;194:83-90. Epub 2016 Aug 23. PMID:
27566200
Article Published Date
: Dec 23, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemosensitizer
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
[+]
Ginsenoside Rb1 shows potential for use in skin care products to protect the skin against damage by fine particles.
Sep 08, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2019 Sep 9 ;8(9). Epub 2019 Sep 9. PMID:
31505827
Article Published Date
: Sep 08, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Ginsenosides
Diseases
:
Air Pollution Linked Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
Ginsenoside Rg1 can inhibit inflammatory responses in human chondrocytes in vitro and reduce articular cartilage damage in vivo.
Mar 09, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Mar 10 ;9(3). Epub 2017 Mar 10. PMID:
28287423
Article Published Date
: Mar 09, 2017
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Ginsenosides
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Chondroprotective
,
Cyclooxygenase 2 Inhibitors
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Prostaglandin PGE2 downregulation
[+]
Red ginseng extract promotes the hair growth in cultured human hair follicles.
Feb 28, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Food. 2015 Mar ;18(3):354-62. Epub 2014 Nov 14. PMID:
25396716
Article Published Date
: Feb 28, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Hair Loss
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Hair Regeneration
,
Plant Extracts
[+]
20 (S)-ginsenoside Rh2 inhibits colorectal cancer cell growth by suppressing the Axl signaling pathway in vitro and in vivo.
Apr 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2022 May ;46(3):396-407. Epub 2021 Jul 12. PMID:
35600769
Article Published Date
: Apr 30, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
Ginseng polysaccharide reduces autoimmune hepatitis inflammatory response.
Jul 24, 2023
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2023 Jul 25 ;116:154859. Epub 2023 May 3. PMID:
37209603
Article Published Date
: Jul 24, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Hepatitis: Autoimmune
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
Additional Keywords
:
Polysaccharides
[+]
Ginsenoside 24-OH-PD from red ginseng inhibits acute T-lymphocytic leukaemia.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2023 ;18(5):e0285966. Epub 2023 May 19. PMID:
37205671
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Acute lymphoblastic leukemia (ALL)
Pharmacological Actions
:
Apoptotic
[+]
Ginsenoside compound K protects against cerebral ischemia/reperfusion injury.
Apr 30, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2023 May ;47(3):408-419. Epub 2022 Oct 20. PMID:
37252276
Article Published Date
: Apr 30, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside F1 attenuates pirarubicin-induced cardiotoxicity.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2023 Jan ;47(1):106-116. Epub 2022 Jul 5. PMID:
36644383
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Antibiotic Toxicity
Pharmacological Actions
:
Cardioprotective
Problem Substances
:
Antibiotics
[+]
Ginsenoside F1 protects the brain against amyloid beta-induced toxicity by regulating IDE and NEP.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Life (Basel). 2022 Jan 1 ;12(1). Epub 2022 Jan 1. PMID:
35054451
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rb1 for overcoming cisplatin-insensitivity of A549/DDP cells.
Jun 30, 2023
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2023 Jul ;115:154776. Epub 2023 Mar 18. PMID:
37087793
Article Published Date
: Jun 30, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cancers: Drug Resistant
,
Carcinoma: Non-Small-Cell Lung
,
Chemotherapy-Induced Toxicity: Cisplatin
,
Lung Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Chemoprotective Agents
[+]
Ginsenoside Rb1 promotes the activation of PPARα pathway via inhibiting FADD to ameliorate heart failure.
May 14, 2023
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2023 May 15 ;947:175676. Epub 2023 Mar 30. PMID:
37001580
Article Published Date
: May 14, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Heart Failure
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
[+]
Ginsenoside Rb3 inhibits osteoclastogenesis via ERK/NF-κB signaling pathway.
Aug 16, 2022
Click here to read the entire abstract
Pubmed Data
: Oral Dis. 2022 Aug 17. Epub 2022 Aug 17. PMID:
35976062
Article Published Date
: Aug 16, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Periodontitis
Pharmacological Actions
:
Osteogenic
[+]
Ginsenoside Rc modulates SIRT6-NRF2 interaction to alleviate alcoholic liver disease.
Nov 08, 2022
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2022 Nov 9 ;70(44):14220-14234. Epub 2022 Oct 27. PMID:
36300841
Article Published Date
: Nov 08, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alcohol Toxicity
,
Alcoholic Liver Disease
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Nrf2 activation
[+]
Ginsenoside Rd promotes cardiac repair after myocardial infarction.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2022 ;16:2767-2782. Epub 2022 Aug 22. PMID:
36033133
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
,
Myocardial Infarction
Pharmacological Actions
:
Cardioprotective
Additional Keywords
:
Heart Regeneration
[+]
Ginsenoside Re inhibits melanogenesis and melanoma growth.
Aug 31, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2023 Sep ;165:115037. Epub 2023 Jun 30. PMID:
37393867
Article Published Date
: Aug 31, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Melanoma
,
Skin Cancer
Pharmacological Actions
:
Antiproliferative
[+]
Ginsenoside Rg1 ameliorates Alzheimer's disease pathology via restoring mitophagy.
Apr 30, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2023 May ;47(3):448-457. Epub 2022 Dec 21. PMID:
37252274
Article Published Date
: Apr 30, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rg1 protects mice against 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced liver injury.
May 16, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: J Ethnopharmacol. 2022 May 17 ;294:115394. Epub 2022 May 17. PMID:
35595219
Article Published Date
: May 16, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance.
Feb 28, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2022 Mar ;46(2):235-247. Epub 2021 Jun 5. PMID:
35509823
Article Published Date
: Feb 28, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Insulin Resistance
Pharmacological Actions
:
Hypoglycemic Agents
,
Insulin Sensitizers
[+]
Ginsenoside Rh1 protects human endothelial cells against lipopolysaccharide-induced inflammatory injury.
Nov 14, 2022
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2022 Nov 15 ;309:120973. Epub 2022 Sep 20. PMID:
36150463
Article Published Date
: Nov 14, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
STAT3 Inhibitor
[+]
Ginsenoside Rh2 inhibits CBP/p300-mediated FOXO3a acetylation and epilepsy-induced oxidative damage.
Nov 14, 2022
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2022 Nov 15:175391. Epub 2022 Nov 15. PMID:
36400161
Article Published Date
: Nov 14, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain: Oxidative Stress
,
Epilepsy
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Ginsenoside Rh3 induces pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in colorectal cancer cells.
Apr 18, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Acta Biochim Biophys Sin (Shanghai). 2023 Apr 19 ;55(4):587-600. PMID:
37092860
Article Published Date
: Apr 18, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Apoptotic
,
Tumor Suppressor Protein p53 Upregulation
[+]
Ginsenoside Rh3 inhibits lung cancer metastasis.
Jun 16, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmaceuticals (Basel). 2022 Jun 17 ;15(6). Epub 2022 Jun 17. PMID:
35745677
Article Published Date
: Jun 16, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Ginsenoside Rh4 suppresses metastasis of gastric cancer.
Apr 08, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2022 Apr 9 ;14(8). Epub 2022 Apr 9. PMID:
35458126
Article Published Date
: Apr 08, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Ginsenoside Rk1 could be applied for the development of effective natural antiphotoaging agents for skin health.
Dec 05, 2022
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2022 Dec 6. Epub 2022 Dec 6. PMID:
36472249
Article Published Date
: Dec 05, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Aging Skin
,
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Photoprotective
[+]
Ginsenoside Rk1 regulates glutamine metabolism in hepatocellular carcinoma through inhibition of the ERK/c-Myc pathway.
Apr 03, 2022
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2022 Apr 4 ;13(7):3793-3811. Epub 2022 Apr 4. PMID:
35316310
Article Published Date
: Apr 03, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Ginsenosides CK as a potential therapeutic approach for treating muscle-wasting conditions associated with obesity.
Apr 30, 2022
Click here to read the entire abstract
Pubmed Data
: J Ginseng Res. 2022 May ;46(3):444-453. Epub 2021 Sep 10. PMID:
35600773
Article Published Date
: Apr 30, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Obesity
,
Sarcopenia
Pharmacological Actions
:
Anti-Apoptotic
[+]
Neuroprotective effects and metabolomics study of protopanaxatriol (PPT) on cerebral ischemia/reperfusion injury.
Jan 15, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2023 Jan 16 ;24(2). Epub 2023 Jan 16. PMID:
36675303
Article Published Date
: Jan 15, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Notoginsenoside R1 facilitates cell angiogenesis by inactivating the Notch signaling during wound healing.
Mar 10, 2023
Click here to read the entire abstract
Pubmed Data
: J Burn Care Res. 2023 Mar 11. Epub 2023 Mar 11. PMID:
36905210
Article Published Date
: Mar 10, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Wound Healing
Pharmacological Actions
:
Angiogenesis Inducing Agents
[+]
Notoginsenoside R1 protects against myocardial ischemia/reperfusion injury.
Jan 30, 2023
Click here to read the entire abstract
Pubmed Data
: Acta Pharmacol Sin. 2023 Jan 31. Epub 2023 Jan 31. PMID:
36721009
Article Published Date
: Jan 30, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Cardioprotective
[+]
Paclitaxel-loaded ginsenoside Rg3 liposomes for drug-resistant cancer therapy.
Sep 23, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Adv Res. 2022 Sep 24. Epub 2022 Sep 24. PMID:
36167294
Article Published Date
: Sep 23, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Breast Cancer
,
Cancers: Multi-Drug Resistant
Pharmacological Actions
:
Chemosensitizer
Additional Keywords
:
Chemothapeutic Synergy: Paclitaxel
,
Tumor Microenvironment
[+]
The ginsenoside Rg1 nanoparticles may be an available blood-brain barrier penetrating agent for ischemic stroke.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Nanomedicine. 2022 ;17:5447-5468. Epub 2022 Nov 18. PMID:
36426373
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Angiogenesis Inducing Agents
,
Neuroprotective Agents
Additional Keywords
:
Blood Brain Barrier
[+]
Ginsenoside Rb2 improves insulin resistance by inhibiting adipocyte pyroptosis.
Nov 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Adipocyte. 2020 Dec ;9(1):302-312. PMID:
32580621
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
Additional Keywords
:
Anti-Obesity Agents
[+]
Ginsenoside Rk1 alleviates LPS-induced depression-like behavior in mice by promoting BDNF and suppressing the neuroinflammatory response.
Sep 30, 2020
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2020 Oct 1 ;530(4):658-664. Epub 2020 Aug 5. PMID:
32768191
Article Published Date
: Sep 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Brain-derived neurotrophic factor modulator
[+]
The dual roles of ginsenosides in improving the anti-tumor efficiency of cyclophosphamide in mammary carcinoma mice.
Aug 23, 2020
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2020 Aug 24:113271. Epub 2020 Aug 24. PMID:
32853742
Article Published Date
: Aug 23, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemotherapeutic
,
Nrf2 activation
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
"Ginsenoside Rg1 promotes peripheral nerve regeneration in rat model of nerve crush injury."
Jul 04, 2010
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2010 Jul 5 ;478(2):66-71. Epub 2010 May 8. PMID:
20438804
Article Published Date
: Jul 04, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Nerve Injuries
Pharmacological Actions
:
Neuritogenic
,
Neuroprotective Agents
Additional Keywords
:
Nerve Regeneration
[+]
20 (R) -ginsenoside Rg3 entrapped in chitosan microspheres may have a beneficial effect against fatigue.
Jan 05, 2017
Click here to read the entire abstract
Pubmed Data
: Curr Drug Deliv. 2017 09 6 ;14(6):867-874. PMID:
27834150
Article Published Date
: Jan 05, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Fatigue
[+]
20 (S)-ginsenoside Rg3 can inhibit the formation of gastric ulcer.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2019 Oct ;43(4):550-561. Epub 2018 Apr 9. PMID:
31695563
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Gastric Ulcer
Pharmacological Actions
:
Gastroprotective
[+]
20(R)-Ginsenoside Rg3 protects SH-SY5Y cells against apoptosis induced by oxygen and glucose deprivation/reperfusion.
Jan 14, 2017
Click here to read the entire abstract
Pubmed Data
: Bioorg Med Chem Lett. 2017 08 15 ;27(16):3867-3871. Epub 2017 Jun 19. PMID:
28709827
Article Published Date
: Jan 14, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
20(R)-ginsenoside Rg3-loaded polyurethane/marine polysaccharide based nanofiber dressings improved burn wound healing potentials.
Sep 30, 2023
Click here to read the entire abstract
Pubmed Data
: Carbohydr Polym. 2023 Oct 1 ;317:121085. Epub 2023 Jun 1. PMID:
37364955
Article Published Date
: Sep 30, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Wound Healing
Additional Keywords
:
Polysaccharides
[+]
20(S)-ginsenoside Rg(3) showed the significant protective effects on cyclophosphamide-induced cell DNA damage and apoptosis.
Jan 31, 2008
Click here to read the entire abstract
Pubmed Data
: Arch Toxicol. 2008 Feb ;82(2):117-23. Epub 2007 Jun 28. PMID:
17598087
Article Published Date
: Jan 31, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
20(S)-ginsenoside Rg3, a neuroprotective agent, inhibits mitochondrial permeability transition pores in rat brain.
Mar 31, 2009
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2009 Apr ;23(4):486-91. PMID:
19003949
Article Published Date
: Mar 31, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Neuroprotective Agents
[+]
20(S)-ginsenoside Rh1 alleviates T2DM induced liver injury.
Aug 31, 2022
Click here to read the entire abstract
Pubmed Data
: Chin J Nat Med. 2022 Sep ;20(9):669-678. PMID:
36162952
Article Published Date
: Aug 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
20(S)-ginsenoside-Rg3 reverses temozolomide resistance and restrains epithelial-mesenchymal transition progression in glioblastoma.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Sci. 2019 Jan ;110(1):389-400. Epub 2018 Dec 14. PMID:
30431207
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cancers: Drug Resistant
,
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Chemosensitizer
[+]
20(s)‑ginseonside‑Rg3 modulation of AMPK/FoxO3 signaling to attenuate mitochondrial dysfunction in a dexamethasone‑injured C2C12 myotube.
Apr 30, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2021 May ;23(5). Epub 2021 Mar 2. PMID:
33649814
Article Published Date
: Apr 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Muscle Atrophy
Pharmacological Actions
:
Genoprotective
Problem Substances
:
Dexamethasone
[+]
A cocktail of betulinic acid, parthenolide, honokiol and ginsenoside Rh2 in liposome systems for lung cancer treatment.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nanomedicine (Lond). 2020 Jan ;15(1):41-54. PMID:
31868113
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Betulinic acid
,
Ginsenosides
,
Honokiol
,
Parthenolide
Diseases
:
Lung Cancer
Pharmacological Actions
:
Chemotherapeutic
Additional Keywords
:
Natural Substance Synergy
[+]
A Ginkgo biloba and ginsenoside Rg3 extract possesses significant protective activities against ADHD-like conditions.
Feb 28, 2014
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2014 Mar ;65:280-92. Epub 2014 Jan 3. PMID:
24394491
Article Published Date
: Feb 28, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Attention Deficit Disorder with Hyperactivity
Pharmacological Actions
:
Antioxidants
,
Cytoprotective
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
A ginseng-containing diet may enhance immunity against SARS-CoV-2.
Jun 05, 2022
Click here to read the entire abstract
Pubmed Data
: Front Biosci (Landmark Ed). 2022 Jun 6 ;27(6):180. PMID:
35748256
Article Published Date
: Jun 05, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Coronavirus Infection
Pharmacological Actions
:
Antiviral Agents
[+]
A natural compound mixture ameliorates psoriasis-like skin lesions.
Dec 31, 2019
Click here to read the entire abstract
Pubmed Data
: Evid Based Complement Alternat Med. 2020 ;2020:9416962. Epub 2020 Oct 22. PMID:
33149756
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Chlorogenic Acid
,
Emodin
,
Genipin
,
Ginsenosides
Diseases
:
Psoriasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
A purified dry extract of ginseng may improve cancer related fatigue via regulation of inflammatory responses and hematopoiesis.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2015 ;2015:197459. Epub 2015 Apr 7. PMID:
25945105
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
,
Fatigue: Cancer-Associated
Pharmacological Actions
:
Chemoprotective Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Additive antiangiogenesis effect of ginsenoside Rg3 with low-dose metronomic temozolomide on rat glioma cells both in vivo and in vitro.
Feb 12, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Exp Clin Cancer Res. 2016 Feb 13 ;35:32. Epub 2016 Feb 13. PMID:
26872471
Article Published Date
: Feb 12, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Glioblastoma
Pharmacological Actions
:
Anti-Angiogenic
,
Antiproliferative
,
Cell cycle arrest
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
All of these experimental results suggested that Ginsenoside Rg3 may serve as a reliable drug for the treatment of patients with keloids.
Feb 28, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2018 Mar ;41(3):1487-1499. Epub 2018 Jan 4. PMID:
29328420
Article Published Date
: Feb 28, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Keloid
Pharmacological Actions
:
Antiproliferative
,
Transforming growth factor beta (TGF-β) inhibitor
[+]
Alleviation of diabetic complications by ginsenoside Rg3-enriched red ginseng extract in western diet-fed mice.
Jun 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2018 Jul ;42(3):352-355. Epub 2017 Apr 24. PMID:
29983617
Article Published Date
: Jun 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Cardiovascular Diseases
,
Diabetic Complications
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
Additional Keywords
:
Plant Extracts
Anti Therapeutic Actions
:
Western Diet
[+]
Alleviative effects of 20(R)-Rg3 on HFD/STZ-induced diabetic nephropathy.
Feb 28, 2021
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2021 Mar 1 ;267:113500. Epub 2020 Oct 19. PMID:
33091499
Article Published Date
: Feb 28, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hypoglycemic Agents
,
NF-kappaB Inhibitor
[+]
Ameliorative effect of ginsenoside Rg1 on dextran sulfate sodium-induced colitis.
Nov 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Transl Med. 2022 Dec ;10(24):1328. PMID:
36660612
Article Published Date
: Nov 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-4 upregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ameliorative effects of Compound K and ginsenoside Rh1 on non-alcoholic fatty liver disease in rats.
Jan 19, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Jan 20 ;7:41144. Epub 2017 Jan 20. PMID:
28106137
Article Published Date
: Jan 19, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
,
Panax Notoginseng
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Ginsenosides
,
Hepatoprotective
,
Nonalcoholic fatty liver disease (NAFLD)
,
Panax Notoginseng
[+]
Ameliorative effects of malonyl ginsenoside from Panax ginseng on glucose-lipid metabolism and insulin resistance.
Mar 09, 2022
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2022 Mar 10:1-20. Epub 2022 Mar 10. PMID:
35282802
Article Published Date
: Mar 09, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
[+]
Analgesic effect and related amino acids regulation of ginsenoside Rg3 in mouse pain models.
Dec 14, 2019
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2019 Dec 15 ;239:117083. Epub 2019 Nov 20. PMID:
31759043
Article Published Date
: Dec 14, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chronic Pain
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
[+]
Anti-ageing effect of red ginseng revealed.
Jun 30, 2018
Click here to read the entire abstract
Pubmed Data
: Phytochem Anal. 2018 Jul ;29(4):387-397. Epub 2018 Mar 24. PMID:
29573298
Article Published Date
: Jun 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Aging
Additional Keywords
:
Plant Extracts
[+]
Anti-hepatitic activity of ginsenoside Ro.
Nov 30, 1991
Click here to read the entire abstract
Pubmed Data
: Planta Med. 1991 Dec ;57(6):523-6. PMID:
1818342
Article Published Date
: Nov 30, 1991
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Anti-inflammatory and anti-gouty-arthritic effect of free Ginsenoside Rb1 and nano ginsenoside Rb1 against MSU induced gouty arthritis.
Nov 30, 2020
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2020 Dec 1 ;332:109285. Epub 2020 Oct 7. PMID:
33038330
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Anti-inflammatory effects of ginsenoside Rg1 and its metabolites ginsenoside Rh1 and 20(S)-protopanaxatriol.
Sep 04, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2015 Sep 5 ;762:333-43. Epub 2015 Jun 6. PMID:
26054809
Article Published Date
: Sep 04, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colitis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-obesity effects of ginsenosides in high-fat diet-fed rats.
May 29, 2019
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2019 May 30. Epub 2019 May 30. PMID:
31144161
Article Published Date
: May 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Antidepressant effect and molecular mechanism of notoginsenoside R1.
Sep 30, 2022
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2022 Oct ;47(20):5599-5609. PMID:
36471978
Article Published Date
: Sep 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Antidepressant effects of ginsenoside Rf on behavioral change in the glial degeneration model of depression by reversing glial loss.
Jun 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2020 Jul ;44(4):603-610. Epub 2019 Aug 22. PMID:
32617040
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
[+]
Antidepressant-like effect of altered Korean red ginseng in mice.
Mar 31, 2011
Click here to read the entire abstract
Pubmed Data
: Behav Med. 2011 Apr ;37(2):42-6. PMID:
21660771
Article Published Date
: Mar 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
Problem Substances
:
Fluoxetine (trade name Prozac)
[+]
Antidepressant-like effects of ginsenosides.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Pharmacol Biochem Behav. 2016 Jan ;140:17-26. Epub 2015 Oct 31. PMID:
26528894
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
[+]
Antiobesity effects of ginsenoside Rg1 on 3T3-L1 preadipocytes and high fat diet-induced obese mice mediated by AMPK.
Jun 26, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2018 Jun 27 ;10(7). Epub 2018 Jun 27. PMID:
29954059
Article Published Date
: Jun 26, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Obesity
Pharmacological Actions
:
Anti-Adipogenic
Additional Keywords
:
Anti-Obesity Agents
[+]
Antitumor activity of ginsenoside Rg3 in melanoma through downregulation of the ERK and Akt pathways.
May 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Oncol. 2019 Jun ;54(6):2069-2079. Epub 2019 Apr 16. PMID:
31081060
Article Published Date
: May 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Melanoma
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Antitumor effect of ginsenoside Rg3 on gallbladder cancer.
Oct 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2018 Nov ;16(5):5687-5696. Epub 2018 Aug 20. PMID:
30344724
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Gallbladder Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Antiviral effect of ginsenosides rk1 against influenza a virus infection.
Mar 03, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2023 Mar 4 ;24(5). Epub 2023 Mar 4. PMID:
36902398
Article Published Date
: Mar 03, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Influenza A
Pharmacological Actions
:
Antiviral Agents
[+]
Attenuating effect of Ginsenoside Rb1 on LPS-induced lung injury in rats.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Inflamm (Lond). 2014 ;11(1):40. Epub 2014 Dec 5. PMID:
25530718
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Berberine and ginsenoside Rb1 ameliorate depression-like behavior.
May 26, 2021
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2021 May 27:1-19. Epub 2021 May 27. PMID:
34049474
Article Published Date
: May 26, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
,
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
[+]
Black ginseng and ginsenoside Rb1 act as potential functional anti-obesity food agents.
Nov 11, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Nov 12 ;11(11). Epub 2019 Nov 12. PMID:
31726767
Article Published Date
: Nov 11, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Black ginseng extract counteracts streptozotocin-induced diabetes.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(1):e0146843. Epub 2016 Jan 11. PMID:
26751692
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 1
,
Diabetes Mellitus: Type 2
,
Hyperglycemia
Pharmacological Actions
:
Anti-Apoptotic
,
Hypoglycemic Agents
Additional Keywords
:
Plant Extracts
[+]
Black ginseng has ameliorative effects against acetaminophen induced hepatotoxicity.
Apr 20, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2017 Apr 21 ;22(4). Epub 2017 Apr 21. PMID:
28430162
Article Published Date
: Apr 20, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
,
Panax Ginseng
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Phytotherapy
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Black phosphorus conjugation of chemotherapeutic ginsenoside Rg3.
Nov 30, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Deliv. 2021 Dec ;28(1):1748-1758. PMID:
34463184
Article Published Date
: Nov 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
[+]
Both ginseng saponins, 20(R)- and 20(S)-ginsenoside-Rg3, possess an ability to inhibit the lung metastasis of tumor cells.
Aug 31, 1995
Click here to read the entire abstract
Pubmed Data
: Biol Pharm Bull. 1995 Sep ;18(9):1197-202. PMID:
8845804
Article Published Date
: Aug 31, 1995
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lung Cancer
,
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
[+]
Brown adipose tissue activation by ginsenoside compound K treatment ameliorates polycystic ovary syndrome.
Jun 24, 2022
Click here to read the entire abstract
Pubmed Data
: Br J Pharmacol. 2022 Jun 25. Epub 2022 Jun 25. PMID:
35751868
Article Published Date
: Jun 24, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Polycystic Ovary Syndrome
[+]
Carbon nanotubes-loaded ginsenosides Rb3 suppresses the PD-1/PD-L1 pathway in triple-negative breast cancer.
Jun 09, 2021
Click here to read the entire abstract
Pubmed Data
: Aging (Albany NY). 2021 Jun 10 ;13. Epub 2021 Jun 10. PMID:
34111025
Article Published Date
: Jun 09, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Antiproliferative
,
Immunomodulatory
[+]
Cardioprotective effect of ginsenoside Rb1 via regulating metabolomics profiling and AMP-activated protein kinase-dependent mitophagy.
Feb 28, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2022 Mar ;46(2):255-265. Epub 2021 Jul 3. PMID:
35509816
Article Published Date
: Feb 28, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Cardioprotective
[+]
Cardioprotective effects of 20(S)-ginsenoside Rh2 against doxorubicin-induced cardiotoxicity.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2012 ;2012:506214. Epub 2012 Oct 17. PMID:
23125868
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Cellular and molecular mechanisms underlying the action of ginsenoside Rg1 against Alzheimer's disease.
Dec 24, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neural Regen Res. 2012 Dec 25 ;7(36):2860-6. PMID:
25317137
Article Published Date
: Dec 24, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Certain ginsenosides inhibit lung inflammatory responses.
Sep 30, 2018
Click here to read the entire abstract
Pubmed Data
: J Ginseng Res. 2018 Oct ;42(4):476-484. Epub 2017 Jun 8. PMID:
30337808
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Combination of the ginsenosides Rb3 and Rb2 exerts protective effects against myocardial ischemia reperfusion injury.
Nov 28, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2019 Nov 29. Epub 2019 Nov 29. PMID:
31789417
Article Published Date
: Nov 28, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Cardioprotective
[+]
Combined ginsenoside Rg3 and transarterial embolization treatment limited metastasis and promoted survival.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Onco Targets Ther. 2014 ;7:1945-54. Epub 2014 Oct 21. PMID:
25364265
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Combining Rp1 with chemotherapeutic agents could circumvent drug resistance and improve treatment efficacy.
Mar 04, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancers (Basel). 2020 Mar 5 ;12(3). Epub 2020 Mar 5. PMID:
32151067
Article Published Date
: Mar 04, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colon Cancer
,
Lung Cancer
,
Ovarian Cancer
Pharmacological Actions
:
Apoptotic
,
Chemotherapeutic
[+]
Components of Astragalus and Panax notoginseng could strengthen the protective effects on cerebral ischemia injury.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2015 ;43(7):1419-38. Epub 2015 Oct 18. PMID:
26477799
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Astragalus
,
Ginsenosides
,
Panax Notoginseng
Diseases
:
Brain Ischemia
,
Inflammation
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
[+]
Compound K protects pancreatic islet cells against apoptosis
Jun 26, 2014
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2014 Jun 27 ;107(1-2):42-9. Epub 2014 May 5. PMID:
24802125
Article Published Date
: Jun 26, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Apoptotic
,
Pancreato Protective Agents
[+]
Comprehensive analysis of lncRNA expression profiles in rats with cerebral ischemia-reperfusion injury after treatment with 20( R)-ginsenoside Rg3.
Jan 27, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Integr Neurosci. 2022 Jan 28 ;21(1):16. PMID:
35164452
Article Published Date
: Jan 27, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Neuroprotective Agents
[+]
Comprehensive analysis of the effect of 20( R)-ginsenoside Rg3 on stroke recovery.
Feb 26, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2022 Feb 27 ;27(5). Epub 2022 Feb 27. PMID:
35268674
Article Published Date
: Feb 26, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cultured wild ginseng root extract fermented by P. pentosaceus contains the distinctive ginsenosides Rg5/Rk1, which may ameliorate memory impairment.
May 19, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Nutrients. 2019 May 20 ;11(5). Epub 2019 May 20. PMID:
31137483
Article Published Date
: May 19, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Memory Disorders: Drug-Induced
Pharmacological Actions
:
Neuroprotective Agents
[+]
Diol-ginsenosides from Korean Red Ginseng delay the development of type 1 diabetes in diabetes-prone biobreeding rats.
Jun 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2020 Jul ;44(4):619-626. Epub 2019 Jun 12. PMID:
32617042
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 1: Prevention
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Risk Reduction
[+]
Doxorubicin nanomedicine based on ginsenoside Rg1 with alleviated cardiotoxicity and enhanced antitumor activity.
Oct 31, 2021
Click here to read the entire abstract
Pubmed Data
: Nanomedicine (Lond). 2021 Nov 1. Epub 2021 Nov 1. PMID:
34719938
Article Published Date
: Oct 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
,
Chemosensitizer
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
[+]
Effect of ginsenoside pre-treatment on 5-hydroxytryptamine system in rats with myocardial infarction and depression.
Aug 31, 2016
Click here to read the entire abstract
Pubmed Data
: Zhonghua Nei Ke Za Zhi. 2016 Sep 1 ;55(9):700-4. PMID:
27586978
Article Published Date
: Aug 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
,
Myocardial Infarction
[+]
Effect of ginsenoside Rg1 in delaying premature ovarian failure induced by D-galactose.
Nov 30, 2020
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2020 Dec ;45(24):6036-6042. PMID:
33496145
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Ovarian Failure
Pharmacological Actions
:
Autophagy Inhibitors
[+]
Effects of ginseng saponins isolated from Red Ginseng roots on burn wound healing in mice.
Jun 30, 2006
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Pharmacol. 2006 Jul ;148(6):860-70. Epub 2006 Jun 12. PMID:
16770323
Article Published Date
: Jun 30, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Wound Healing
[+]
Effects of ginsenoside compound K on colitis-associated colorectal cancer and gut microbiota profiles.
Mar 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Transl Med. 2022 Apr ;10(7):408. PMID:
35530961
Article Published Date
: Mar 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colitis
,
Colorectal Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
Gastrointestinal Agents
[+]
Effects of ginsenoside Rg1 on glucose metabolism and liver injury in streptozotocin-induced type 2 diabetic rats.
Mar 29, 2017
Click here to read the entire abstract
Pubmed Data
: Genet Mol Res. 2017 Mar 30 ;16(1). Epub 2017 Mar 30. PMID:
28362999
Article Published Date
: Mar 29, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Apoptotic
,
Hepatoprotective
,
Hypoglycemic Agents
,
Hypolipidemic
[+]
Effects of ginsenoside Rg3 on inhibiting differentiation, adipogenesis, and ER stress-mediated cell death in brown adipocytes.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2021 ;2021:6668665. Epub 2021 Mar 16. PMID:
33815558
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Metabolic Diseases
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Anti-Obesity Agents
[+]
Effects of notoginsenoside R1 on attenuating depressive behavior induced by chronic stress.
Jun 25, 2021
Click here to read the entire abstract
Pubmed Data
: Drug Dev Res. 2021 Jun 26. Epub 2021 Jun 26. PMID:
34173680
Article Published Date
: Jun 25, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
[+]
EGFR signaling-dependent inhibition of glioblastoma growth by ginsenoside Rh2.
May 31, 2014
Click here to read the entire abstract
Pubmed Data
: Tumour Biol. 2014 Jun ;35(6):5593-8. Epub 2014 Feb 21. PMID:
24557544
Article Published Date
: May 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Glioblastoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Epidermal growth factor receptor (EGFR) inhibitor
[+]
Endostar combined with ginsenoside Rg3 has stronger inhibiting effect on breast cancer tumor growth in tumor-bearing mice than single drug.
Jan 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Trop Med. 2016 Feb ;9(2):180-3. Epub 2016 Jan 11. PMID:
26919952
Article Published Date
: Jan 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor A Inhibitor
,
Vascular Endothelial Growth Factor C Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Evaluation of chemopreventive action of Ginsenoside Rp1.
Dec 31, 2005
Click here to read the entire abstract
Pubmed Data
: Biofactors. 2006 ;26(1):29-43. PMID:
16614481
Article Published Date
: Dec 31, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lipid Peroxidation
,
Skin Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
Superoxide Dismutase Up-regulation
[+]
Explosively puffed ginseng ameliorates ionizing radiation-induced injury of colon.
Apr 30, 2019
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2019 May ;22(5):490-498. PMID:
31084541
Article Published Date
: Apr 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Pharmacological Actions
:
Antioxidants
,
Radioprotective
Anti Therapeutic Actions
:
Low Dose Ionizing Radiation
[+]
Fermented and aged ginseng sprouts and their main component, compound K, alleviate asthma parameters.
Oct 17, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2022 Oct 18 ;11(10). Epub 2022 Oct 18. PMID:
36290772
Article Published Date
: Oct 17, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Ginseng
,
Ginsenosides
Diseases
:
Asthma
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Asthmatic Agents
,
Anti-Inflammatory Agents
,
Antioxidants
[+]
Fermented black ginseng has beneficial effects on wound healing.
Sep 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2018 Oct ;42(4):524-531. Epub 2017 Jul 25. PMID:
30337813
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Ginseng
,
Ginsenosides
Diseases
:
Wound Healing
[+]
Fermented red ginseng and ginsenoside Rd alleviate ovalbumin-induced allergic rhinitis.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2019 Oct ;43(4):635-644. Epub 2019 Mar 7. PMID:
31695569
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Allergic Rhinitis
Pharmacological Actions
:
interleukin-13 down-regulation
,
Interleukin-4 downregulation
,
Interleukin-5 downregulation
[+]
findings provide strong evidence that ginsenoside-Rg1 can protect the liver against exhaustive exercise-induced oxidative damage.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2012 ;2012:932165. Epub 2011 Sep 20. PMID:
21941591
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Exercise-Induced Tissue Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Flavored black ginseng exhibited antitumor activity via improving immune function and inducing apoptosis.
May 23, 2017
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2017 May 24 ;8(5):1880-1889. PMID:
28426048
Article Published Date
: May 23, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cancers: All
Pharmacological Actions
:
Antineoplastic Agents
,
Apoptotic
,
Immunomodulatory
Additional Keywords
:
Plant Extracts
[+]
Gastroprotective effects of ginsenoside Rh4 against ethanol-induced gastric mucosal injury.
Jun 05, 2023
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2023 Jun 6 ;14(11):5167-5181. Epub 2023 Jun 6. PMID:
37184519
Article Published Date
: Jun 05, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alcohol Toxicity
,
Gastric Ulcer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Gastroprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
[+]
Ginkgo biloba extract improves brain uptake of ginsenosides by increasing blood-brain barrier permeability.
Jan 09, 2020
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2020 Jan 10 ;246:112243. Epub 2019 Sep 18. PMID:
31541722
Article Published Date
: Jan 09, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginkgo biloba
,
Ginsenosides
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Blood Brain Barrier
[+]
Ginseng oligopeptides could be a novel natural agent for relieving exercise fatigue.
Dec 12, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2016 Dec 13 ;8(12). Epub 2016 Dec 13. PMID:
27983571
Article Published Date
: Dec 12, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
,
Panax Ginseng
Diseases
:
Fatigue: Excercise-Induced
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Antioxidants
,
Fatigue: Excercise-Induced
,
Ginsenosides
,
Panax Ginseng
,
Polysaccharides
[+]
Ginseng reduces neurologic damage in subarachanoid hemorrhage.
Mar 31, 2010
Click here to read the entire abstract
Pubmed Data
: Curr Neurovasc Res. 2010 Mar 31. Epub 2010 Mar 31. PMID:
20353383
Article Published Date
: Mar 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cerebral Aneurysm
,
Stroke
,
Subarachnoid hemorrhage
[+]
Ginseng saponin enriched in Rh1 and Rg2 ameliorates nonalcoholic fatty liver disease.
Mar 04, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2021 Mar 5 ;13(3). Epub 2021 Mar 5. PMID:
33807927
Article Published Date
: Mar 04, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
Ginseng saponin metabolite 20(S)-protopanaxadiol relieves pulmonary fibrosis by multiple-targets signaling pathways.
Jun 30, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2023 Jul ;47(4):543-551. Epub 2023 Jan 7. PMID:
37397411
Article Published Date
: Jun 30, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Pulmonary Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
[+]
Ginsenoside 20(S)-protopanaxadiol attenuates depressive-like behaviour and neuroinflammation in chronic unpredictable mild stress.
May 24, 2020
Click here to read the entire abstract
Pubmed Data
: Behav Brain Res. 2020 May 25:112710. Epub 2020 May 25. PMID:
32464121
Article Published Date
: May 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antidepressive Agents
[+]
Ginsenoside 20(S)-Rg3 inhibited the Warburg effect in ovarian cancer cells via H19/miR-324-5p/PKM2 pathway.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;51(3):1340-1353. Epub 2018 Nov 27. PMID:
30481782
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Antiproliferative
,
MicroRNA modulator
Additional Keywords
:
Warburg Effect
[+]
Ginsenoside 20(S)-Rg3 upregulates FDFT1 via reducing miR-4425 to inhibit ovarian cancer progression.
Aug 29, 2020
Click here to read the entire abstract
Pubmed Data
: Arch Biochem Biophys. 2020 Aug 30:108569. Epub 2020 Aug 30. PMID:
32877662
Article Published Date
: Aug 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
MicroRNA modulator
[+]
Ginsenoside 20(s)-Rh2 as potent natural histone deacetylase inhibitors suppressing the growth of human leukemia cells.
Dec 04, 2015
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2015 Dec 5 ;242:227-34. Epub 2015 Oct 19. PMID:
26482938
Article Published Date
: Dec 04, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Leukemia
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Histone deacetylase inhibitor
[+]
Ginsenoside 20(S)-Rh2 enhanced the antibacterial effects of ciprofloxacin in vitro and in vivo.
Oct 04, 2014
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2014 Oct 5 ;740:277-84. Epub 2014 Jul 20. PMID:
25054686
Article Published Date
: Oct 04, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Staphylococcus aureus infection
Pharmacological Actions
:
Anti-Bacterial Agents
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Ginsenoside 25-OCH3-PPD could be used to curve the development of hepatic fibrosis.
Jul 10, 2018
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2018 Jul 11 ;66(27):7023-7035. Epub 2018 Jul 2. PMID:
29929367
Article Published Date
: Jul 10, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Liver Cirrhosis
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Fibrotic
,
Hepatoprotective
[+]
Ginsenoside AD-2 ameliorating lipopolysaccharide-induced activation in HSC-T6 cells and carbon tetrachloride-induced hepatic fibrosis.
Jan 15, 2023
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2023 Jan 16. Epub 2023 Jan 16. PMID:
36644954
Article Published Date
: Jan 15, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
,
Liver Fibrosis
Pharmacological Actions
:
Hepatoprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Transforming growth factor beta (TGF-β) inhibitor
[+]
Ginsenoside ameliorated diabetic cognitive decline.
Jun 09, 2018
Click here to read the entire abstract
Pubmed Data
: Med Sci Monit. 2018 Jun 10 ;24:3922-3928. Epub 2018 Jun 10. PMID:
29886506
Article Published Date
: Jun 09, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes: Cognitive Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside CK induces apoptosis in triple-negative breast cancer cells by targeting glutamine metabolism.
May 22, 2022
Click here to read the entire abstract
Pubmed Data
: Biochem Pharmacol. 2022 May 23:115101. Epub 2022 May 23. PMID:
35618001
Article Published Date
: May 22, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Apoptotic
[+]
Ginsenoside CK inhibits obese insulin resistance by activating PPARγ to interfere with macrophage activation.
May 25, 2021
Click here to read the entire abstract
Pubmed Data
: Microb Pathog. 2021 May 26 ;157:105002. Epub 2021 May 26. PMID:
34051328
Article Published Date
: May 25, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
,
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside CK inhibits TGF- β-induced epithelial-mesenchymal transition in A549 cell via SIRT1.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2021 ;2021:9140191. Epub 2021 Dec 12. PMID:
34934771
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Ginsenoside CK may be a novel therapeutic potential for the treatment of neuroblastoma.
Aug 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2019 Sep 1 ;20(17). Epub 2019 Sep 1. PMID:
31480534
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Neuroblastoma
Pharmacological Actions
:
Apoptotic
,
Autophagy Inhibitors
[+]
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Jul 29, 2019
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2019 Jul 30. Epub 2019 Jul 30. PMID:
31364016
Article Published Date
: Jul 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Ginsenoside compound K attenuates cognitive deficits in vascular dementia.
Feb 28, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pharmacol Sci. 2019 Mar ;139(3):223-230. Epub 2019 Feb 13. PMID:
30799178
Article Published Date
: Feb 28, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
,
Dementia
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside compound K attenuates the development of atherosclerosis.
Jul 07, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2016 Jul 8 ;17(7). Epub 2016 Jul 8. PMID:
27399689
Article Published Date
: Jul 07, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Atherosclerosis
,
Fatty Liver
Pharmacological Actions
:
Anti-atherogenic
,
Anti-Inflammatory Agents
[+]
Ginsenoside compound K inhibits obesity-induced insulin resistance.
Mar 07, 2022
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2022 Mar 8. Epub 2022 Mar 8. PMID:
35260867
Article Published Date
: Mar 07, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Anti-Obesity Agents
[+]
Ginsenoside compound K might be a potential therapeutic candidate for human liver cancer.
Jun 18, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2018 Jun 19 ;23(6). Epub 2018 Jun 19. PMID:
29921768
Article Published Date
: Jun 18, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Liver Cancer
Pharmacological Actions
:
Apoptotic
,
STAT3 Inhibitor
[+]
Ginsenoside compound K protects against obesity.
Jun 01, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmaceutics. 2022 Jun 2 ;14(6). Epub 2022 Jun 2. PMID:
35745765
Article Published Date
: Jun 01, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Obesity
Pharmacological Actions
:
Hypolipidemic
Additional Keywords
:
Anti-Obesity Agents
[+]
Ginsenoside compound K reduces the progression of Huntington's disease.
Jun 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2022 Jul ;46(4):572-584. Epub 2021 Nov 11. PMID:
35818427
Article Published Date
: Jun 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Huntington Disease
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Ginsenoside compound K suppresses tumor growth in the 22Rv1 xenograft model.
Nov 07, 2022
Click here to read the entire abstract
Pubmed Data
: FEBS J. 2022 Nov 8. Epub 2022 Nov 8. PMID:
36349420
Article Published Date
: Nov 07, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside compound-K inhibits the activity of B cells through inducing IgD-B cell receptor endocytosis in mice with collagen-induced arthritis.
Jun 03, 2019
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2019 Jun 4. Epub 2019 Jun 4. PMID:
31165333
Article Published Date
: Jun 03, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Arthritis
Pharmacological Actions
:
Immunomodulatory
[+]
Ginsenoside extract from ginseng extends lifespan and health span in Caenorhabditis elegans.
Jun 09, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Funct. 2021 Jun 10. Epub 2021 Jun 10. PMID:
34109970
Article Published Date
: Jun 09, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Aging
Pharmacological Actions
:
Antioxidants
[+]
Ginsenoside extract might serve as a potential agent for the prevention of NAFLD.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2021 ;12:622841. Epub 2021 Feb 12. PMID:
33679403
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Hepatoprotective
[+]
Ginsenoside F2 may be a novel therapeutic approach for treating skin inflammation.
Sep 29, 2016
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2016 Sep 30 ;478(4):1713-9. Epub 2016 Sep 3. PMID:
27596969
Article Published Date
: Sep 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Dermatitis
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-17 downregulation
[+]
Ginsenoside F2 reduces hair loss by controlling apoptosis.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2014 ;37(5):755-63. PMID:
24789999
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Hair Loss
Pharmacological Actions
:
Anti-Apoptotic
[+]
Ginsenoside F4 alleviates skeletal muscle insulin resistance.
Sep 18, 2023
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2023 Sep 19. Epub 2023 Sep 19. PMID:
37726223
Article Published Date
: Sep 18, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Insulin Resistance
Pharmacological Actions
:
Insulin Sensitizers
[+]
Ginsenoside GRb1 could reduce the cell apoptosis induced by spinal cord ischemia-reperfusion through inhibiting oxidative stress.
Aug 13, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Orthop Surg Res. 2019 Aug 14 ;14(1):259. Epub 2019 Aug 14. PMID:
31412899
Article Published Date
: Aug 13, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Ischemia
,
Spinal Cord Injuries
Pharmacological Actions
:
Antioxidants
[+]
Ginsenoside has an anti-neuroinflammation effect in a rat model of Alzheimer disease.
Jan 03, 2011
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2011 Jan 3;487(1):70-2. Epub 2010 Oct 7. PMID:
20933058
Article Published Date
: Jan 03, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Ginsenoside holds a promising potential as a pharmaceutical excipient in the pharmaceutical industries to increase the utility of various bioactives.
Jun 30, 2017
Click here to read the entire abstract
Pubmed Data
: Arch Pharm Res. 2017 Jul ;40(7):864-874. Epub 2017 Jul 15. PMID:
28712035
Article Published Date
: Jun 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Ginsenosides
Additional Keywords
:
Increased Bioavailability
[+]
Ginsenoside M1 induces apoptosis and inhibits the migration of human oral cancer cells.
Dec 18, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2020 Dec 19 ;21(24). Epub 2020 Dec 19. PMID:
33352689
Article Published Date
: Dec 18, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Oral Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Tumor Suppressor Protein p53 Upregulation
[+]
Ginsenoside metabolite compound K exerts anti-inflammatory and analgesic effects via downregulating COX2.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2019 Feb ;27(1):157-166. Epub 2018 Jun 26. PMID:
29946770
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Postaglandin PGE2 downregulation
[+]
Ginsenoside ompound K reduces neuronal damage and improves neuronal synaptic dysfunction by targeting Aβ.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2023 ;14:1103012. Epub 2023 Feb 16. PMID:
36873999
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Ginsenoside protects against AKI via activation of HIF 1α and VEGF A in the kidney brain axis.
Jan 14, 2020
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2020 Jan 15. Epub 2020 Jan 15. PMID:
31985021
Article Published Date
: Jan 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chronic Kidney Disease (CKD)
,
Kidney Damage
Pharmacological Actions
:
Antioxidants
,
Renoprotective
[+]
Ginsenoside Rb 1 inhibits monoiodoacetate-induced osteoarthritis.
Feb 28, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2021 Mar ;45(2):287-294. Epub 2020 Jan 21. PMID:
33841009
Article Published Date
: Feb 28, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Osteoprotective
[+]
Ginsenoside Rb1 administration attenuates focal cerebral ischemic reperfusion injury.
Sep 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2018 Oct ;16(4):3020-3026. Epub 2018 Jul 26. PMID:
30214520
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rb1 alleviated high fat diet-induced apoptosis of hepatocytes of mice via PPAR-γ.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2020 ;2020:2315230. Epub 2020 Jul 13. PMID:
32733933
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
High Fat Diet
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Ginsenoside Rb1 alleviates alcohol-induced liver injury.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2021 ;12:616409. Epub 2021 Feb 26. PMID:
33716743
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alcoholic Liver Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rb1 alleviates bleomycin-induced pulmonary inflammation and fibrosis.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2022 ;16:1793-1809. Epub 2022 Jun 13. PMID:
35719213
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
[+]
Ginsenoside Rb1 alleviates chronic intermittent hypoxia-induced diabetic cardiomyopathy.
Sep 30, 2023
Click here to read the entire abstract
Pubmed Data
: J Tradit Chin Med. 2023 Oct ;43(5):906-914. PMID:
37679978
Article Published Date
: Sep 30, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes: Cardiovascular Illness
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
[+]
Ginsenoside Rb1 alleviates colitis in mice.
Dec 01, 2020
Click here to read the entire abstract
Pubmed Data
: Acta Pharmacol Sin. 2020 Dec 2. Epub 2020 Dec 2. PMID:
33268823
Article Published Date
: Dec 01, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colitis
Pharmacological Actions
:
Anti-Apoptotic
,
Gastroprotective
[+]
Ginsenoside Rb1 alleviates liver injury induced by 3-chloro-1,2-propanediol by stimulating autophagic flux.
Nov 30, 2021
Click here to read the entire abstract
Pubmed Data
: J Food Sci. 2021 Dec ;86(12):5503-5515. Epub 2021 Nov 23. PMID:
34812491
Article Published Date
: Nov 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Ginsenoside Rb1 alleviates ox-LDL-induced vascular endothelium senescence via the SIRT1/Beclin-1/autophagy axis.
Oct 24, 2019
Click here to read the entire abstract
Pubmed Data
: J Cardiovasc Pharmacol. 2019 Oct 25. Epub 2019 Oct 25. PMID:
31658172
Article Published Date
: Oct 24, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Hyperlipidemia
,
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
,
SIRT1 Activator
[+]
Ginsenoside Rb1 ameliorates autophagy of hypoxia cardiomyocytes.
Jul 17, 2018
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2018 Jul 18. Epub 2018 Jul 18. PMID:
30088211
Article Published Date
: Jul 17, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Hypoxia
Pharmacological Actions
:
Cardioprotective
[+]
Ginsenoside Rb1 ameliorates cisplatin-induced learning and memory impairments.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2019 Oct ;43(4):499-507. Epub 2017 Jul 25. PMID:
31695559
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemoprotective Agents
,
Neuroprotective Agents
[+]
Ginsenoside Rb1 ameliorates diabetic arterial stiffening via AMPK pathway.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2021 ;12:753881. Epub 2021 Oct 12. PMID:
34712140
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Arterial Hardening: Elasticity
,
Diabetic Complications
[+]
Ginsenoside Rb1 ameliorates glycemic disorder in mice with high fat diet-induced obesity.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2021 ;12:756491. Epub 2021 Nov 24. PMID:
34899310
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 2
,
Obesity
Pharmacological Actions
:
Hypoglycemic Agents
,
Insulin Sensitizers
[+]
Ginsenoside Rb1 ameliorates Staphylococcus aureus induced lung injury.
May 02, 2019
Click here to read the entire abstract
Pubmed Data
: Microb Pathog. 2019 May 3. Epub 2019 May 3. PMID:
31059756
Article Published Date
: May 02, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lung Injury: Acute
,
Staphylococcus aureus infection
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rb1 and baicalin might promote the proliferation and differentiation of endogenous neural stem cells.
Oct 12, 2017
Click here to read the entire abstract
Pubmed Data
: Brain Res. 2017 Oct 13. Epub 2017 Oct 13. PMID:
29038007
Article Published Date
: Oct 12, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Baicalein
,
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside rb1 and rg3 attenuate glucocorticoid-induced neurotoxicity.
Jul 31, 2010
Click here to read the entire abstract
Pubmed Data
: Cell Mol Neurobiol. 2010 Aug ;30(6):857-62. Epub 2010 Mar 25. PMID:
20336484
Article Published Date
: Jul 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Anxiety
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
Problem Substances
:
Dexamethasone
[+]
Ginsenoside Rb1 attenuates angiotensin II-induced abdominal aortic aneurysm.
Sep 30, 2015
Click here to read the entire abstract
Pubmed Data
: Vascul Pharmacol. 2015 Oct ;73:86-95. Epub 2015 Apr 22. PMID:
25912763
Article Published Date
: Sep 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]
Ginsenoside Rb1 attenuates cardiomyocyte apoptosis induced by myocardial ischemia reperfusion injury.
Jan 27, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2020 Jan 28 ;125:109913. Epub 2020 Jan 28. PMID:
32006902
Article Published Date
: Jan 27, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Ginsenoside Rb1 attenuates intestinal ischemia/reperfusion‑induced inflammation and oxidative stress.
Mar 11, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2019 Mar 12. Epub 2019 Mar 12. PMID:
30864725
Article Published Date
: Mar 11, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
,
Intestinal Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Ginsenoside Rb1 attenuates lipopolysaccharide-induced neural damage.
Dec 29, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Integr Neurosci. 2021 Dec 30 ;20(4):813-823. PMID:
34997706
Article Published Date
: Dec 29, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
[+]
Ginsenoside Rb1 could inhibit cardiomyocyte apoptosis induced by ischemia-reperfusion, thus alleviating ischemia-reperfusion injury.
Dec 31, 2001
Click here to read the entire abstract
Pubmed Data
: J Huazhong Univ Sci Technolog Med Sci. 2002 ;22(3):212-5. PMID:
12658806
Article Published Date
: Dec 31, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Ginsenoside Rb1 demonstrated inhibitory effects on hypertrophic scars.
Mar 04, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2015 Mar 5 ;750:151-9. Epub 2015 Jan 22. PMID:
25620132
Article Published Date
: Mar 04, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Burns
,
Scars
,
Wound Healing
[+]
Ginsenoside Rb1 exerts anti-inflammatory effects in vitro and in vivo.
Feb 25, 2020
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2020 Feb 26 ;69:153197. Epub 2020 Feb 26. PMID:
32146298
Article Published Date
: Feb 25, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Ginsenoside Rb1 exerts antidepressant-like effects via suppression inflammation and activation of AKT pathway.
Jan 22, 2021
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2021 01 23 ;744:135561. Epub 2020 Dec 24. PMID:
33359924
Article Published Date
: Jan 22, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rb1 exerts cardioprotective effects against myocardial ischemia reperfusion injury in diabetic rats.
Sep 30, 2011
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2011 Oct ;38(7):4327-35. Epub 2010 Nov 27. PMID:
21113666
Article Published Date
: Sep 30, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetic Complications
,
Hypertension
,
Myocardial Infarction
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Ginsenoside Rb1 exerts neuroprotective effects through regulation of Lactobacillus helveticus abundance and GABAA receptor expression.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2020 Jan ;44(1):86-95. Epub 2018 Sep 19. PMID:
32095096
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Pharmacological Actions
:
Gastrointestinal Agents
,
Neuroprotective Agents
[+]
Ginsenoside Rb1 exerts protective effects against acetaminophen-induced hepatotoxicity.
Dec 01, 2019
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2019 Dec 2:1-17. Epub 2019 Dec 2. PMID:
31786947
Article Published Date
: Dec 01, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Ginsenoside Rb1 from Panax ginseng attenuates monoiodoacetate-induced osteoarthritis.
Jul 21, 2022
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2022 Jul 22:e14340. Epub 2022 Jul 22. PMID:
35866931
Article Published Date
: Jul 21, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
MicroRNA modulator
[+]
Ginsenoside Rb1 has beneficial effects on oxidative stress injury in rat spinal cords.
Jul 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2018 Aug ;16(2):1079-1086. Epub 2018 Jun 12. PMID:
30116359
Article Published Date
: Jul 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
[+]
Ginsenoside Rb1 has potential for use as a therapeutic agent in osteoarthritis patients.
Mar 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2012 Apr ;36(2):161-8. PMID:
23717116
Article Published Date
: Mar 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Hydrogen Peroxide Induced Toxicity
,
Osteoarthritis
Pharmacological Actions
:
Antioxidants
,
Chondroprotective
[+]
Ginsenoside Rb1 improves brain, lung, and intestinal barrier damage in middle cerebral artery occlusion/reperfusion.
Jul 31, 2022
Click here to read the entire abstract
Pubmed Data
: Chin J Nat Med. 2022 Aug ;20(8):561-571. PMID:
36031228
Article Published Date
: Jul 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Ischemia
,
Middle Cerebral Artery Occlusion (MCAO)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Ginsenoside Rb1 improves cardiac function and remodeling in heart failure.
Aug 04, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Anim. 2017 Aug 5 ;66(3):217-228. Epub 2017 Mar 30. PMID:
28367863
Article Published Date
: Aug 04, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Heart Failure
Pharmacological Actions
:
Cardioprotective
Additional Keywords
:
Phytotherapy
[+]
Ginsenoside Rb1 improves cognitive impairment induced by insulin resistance.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2020 ;2020:3905719. Epub 2020 May 20. PMID:
32550230
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cognitive Decline/Dysfunction
,
Insulin Resistance
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rb1 improves energy metabolism after spinal cord injury.
May 31, 2023
Click here to read the entire abstract
Pubmed Data
: Neural Regen Res. 2023 Jun ;18(6):1332-1338. PMID:
36453420
Article Published Date
: May 31, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Brain-derived neurotrophic factor modulator
,
Neuroprotective Agents
[+]
Ginsenoside Rb1 improves intestinal aging.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:991597. Epub 2022 Sep 27. PMID:
36238549
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Aging
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Ginsenoside Rb1 improves learning and memory ability through its anti-inflammatory effect in Aβ1-40 induced Alzheimer's disease of rats.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Transl Res. 2019 ;11(5):2955-2968. Epub 2019 May 15. PMID:
31217866
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
[+]
Ginsenoside Rb1 improves metabolic disorder in high-fat diet-induced obesity.
Dec 31, 2021
Click here to read the entire abstract
Pubmed Data
: Front Microbiol. 2022 ;13:826487. Epub 2022 Apr 19. PMID:
35516426
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
High Fat Diet
,
Metabolic Diseases
,
Obesity
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Ginsenoside Rb1 improves post-cardiac arrest myocardial stunning and cerebral outcomes.
Mar 05, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2023 Mar 6 ;24(5). Epub 2023 Mar 6. PMID:
36902487
Article Published Date
: Mar 05, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cardiac Arrest
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
,
Nrf2 activation
[+]
Ginsenoside Rb1 improves postoperative fatigue syndrome by reducing skeletal muscle oxidative stress.
Oct 04, 2014
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2014 Oct 5 ;740:480-7. Epub 2014 Jun 27. PMID:
24975098
Article Published Date
: Oct 04, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Fatigue
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
[+]
Ginsenoside Rb1 inhibit apoptosis in rat model of Alzheimer’s disease.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Transl Res. 2018 ;10(3):796-805. Epub 2018 Mar 15. PMID:
29636869
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Ginsenoside Rb1 inhibited high glucose-induced oxidative stress, DNA damage, and cell apoptosis in cultured retinal capillary endothelial cells.
Oct 04, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2019 Oct 5 ;20(19). Epub 2019 Oct 5. PMID:
31590397
Article Published Date
: Oct 04, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetic Retinopathy
,
DNA damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Apoptotic
[+]
Ginsenoside Rb1 inhibits ferroptosis to ameliorate hypoxic-ischemic brain damage.
Jul 31, 2023
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2023 Aug ;121:110503. Epub 2023 Jun 24. PMID:
37364327
Article Published Date
: Jul 31, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rb1 interfered with macrophage activation by activating PPARγ to inhibit insulin resistance in obesity.
Mar 29, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2023 Mar 30 ;28(7). Epub 2023 Mar 30. PMID:
37049846
Article Published Date
: Mar 29, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 2
,
Inflammation
,
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Insulin Sensitizers
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rb1 is a promising candidate for pulmonary hypertension prevention.
Nov 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2020 Dec ;58(1):1055-1063. PMID:
33096951
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Hypertension: Pulmonary
Pharmacological Actions
:
Antihypertensive Agents
[+]
Ginsenoside Rb1 may attenuate cancer-induced bone pain via inhibiting the activation of microglia and glial-derived proinflammatory cytokines.
Apr 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2019 May ;17(5):3859-3866. Epub 2019 Mar 18. PMID:
30988771
Article Published Date
: Apr 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cancer: Pain
Pharmacological Actions
:
Antinoceceptive
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rb1 may attenuate the isoflurane/surgery-induced cognitive impairment by inhibiting neuroinflammation and oxidative stress.
Apr 30, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Environ Sci. 2017 May ;30(5):363-372. PMID:
28549492
Article Published Date
: Apr 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cognitive Decline/Dysfunction
,
Inflammation
,
Oxidative Stress
,
Postoperative Recovery
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rb1 may be an effective treatment to prevent the secondary brain damage induced by stroke.
Apr 17, 2017
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2017 Apr 18 ;202:138-146. Epub 2017 Jan 5. PMID:
28065779
Article Published Date
: Apr 17, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke: Attenuation/Recovery
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rb1 may offer a potential therapeutic option for patients with HIV-associated neurocognitive disorders.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2018 ;46(3):551-566. PMID:
29690789
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
HIV Infections
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Blood Brain Barrier
[+]
Ginsenoside Rb1 may prevent ischemia and reperfusion induced cardiac injury.
Mar 21, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Mar 22 ;7:44579. Epub 2017 Mar 22. PMID:
28327605
Article Published Date
: Mar 21, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Cardioprotective
[+]
Ginsenoside Rb1 may serve as a potential candidate for the treatment of Parkinson's disease.
Jul 16, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Aging (Albany NY). 2019 Jul 17 ;11(14):5008-5034. PMID:
31314744
Article Published Date
: Jul 16, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rb1 might effectively release local cerebral ischemia by down-regulating the IL-1 beta expression.
Nov 30, 2013
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013 Dec ;33(12):1696-700. PMID:
24517072
Article Published Date
: Nov 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
Ginsenoside Rb1 mitigates Escherichia coli lipopolysaccharide-induced endometritis.
Nov 22, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2021 Nov 23 ;26(23). Epub 2021 Nov 23. PMID:
34885671
Article Published Date
: Nov 22, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Endometritis
,
Escherichia coli Infections
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Ginsenoside Rb1 prevents osteoporosis via the AHR/PRELP/NF-κB signaling axis.
May 24, 2022
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2022 May 25 ;104:154205. Epub 2022 May 25. PMID:
35716470
Article Published Date
: May 24, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Osteoporosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Osteoprotective
[+]
Ginsenoside Rb1 promotes motor functional recovery and axonal regeneration in post-stroke.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Brain Res Bull. 2020 Jan ;154:51-60. Epub 2019 Nov 9. PMID:
31715311
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Nerve Regeneration
[+]
Ginsenoside Rb1 protects against diabetes-associated metabolic disorders.
Feb 28, 2023
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2023 Mar 1 ;303:115997. Epub 2022 Dec 9. PMID:
36509256
Article Published Date
: Feb 28, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 2
,
Insulin Resistance
Pharmacological Actions
:
Gastrointestinal Agents
,
Hypoglycemic Agents
[+]
Ginsenoside Rb1 protects against diabetic cardiomyopathy.
Dec 31, 2021
Click here to read the entire abstract
Pubmed Data
: J Inflamm Res. 2022 ;15:71-83. Epub 2022 Jan 5. PMID:
35023944
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cardiomyopathy
Pharmacological Actions
:
Cardioprotective
[+]
Ginsenoside Rb1 protects against myocardium ischemia/reperfusion injury in diabetic rats.
Dec 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Biomed Biotechnol. 2011 ;2011:767930. Epub 2011 Oct 16. PMID:
22013385
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetic Complications
,
Myocardial Ischemia
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Ginsenoside Rb1 protects against spinal cord ischemia-reperfusion injury.
Sep 01, 2018
Click here to read the entire abstract
Pubmed Data
: Exp Mol Pathol. 2018 Sep 2 ;105(3):229-235. Epub 2018 Sep 2. PMID:
30184471
Article Published Date
: Sep 01, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Ischemia
,
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Apoptotic
[+]
Ginsenoside Rb1 protects dopaminergic neurons from inflammatory injury induced by intranigral lipopolysaccharide injection.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neural Regen Res. 2019 Oct ;14(10):1814-1822. PMID:
31169200
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Ginsenoside Rb1 protects from Staphylococcus aureus-induced oxidative damage and apoptosis.
Jul 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ecotoxicol Environ Saf. 2021 Aug ;219:112353. Epub 2021 May 23. PMID:
34034046
Article Published Date
: Jul 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Staphylococcus aureus infection
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Ginsenoside Rb1 protects hippocampal neurons in depression.
Sep 11, 2023
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2023 Sep 12 ;121:155083. Epub 2023 Sep 12. PMID:
37722244
Article Published Date
: Sep 11, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Ginsenoside Rb1 reduced body weight and improved glycolipid metabolism by upregulating PPARγ and AQP7 protein levels.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Metab (Lond). 2020 ;17:69. Epub 2020 Aug 17. PMID:
32821266
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Ginsenoside Rb1 reduces D-GalN/LPS-induced acute liver injury.
Jun 27, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Transl Hepatol. 2022 Jun 28 ;10(3):474-485. Epub 2021 Aug 19. PMID:
35836757
Article Published Date
: Jun 27, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Ginsenoside Rb1 reduces oxidative/carbonyl stress damage and ameliorates inflammation in the lung of streptozotocin-induced diabetes.
Nov 30, 2022
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2022 Dec ;60(1):2229-2236. PMID:
36367996
Article Published Date
: Nov 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetic Complications
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Transforming growth factor beta (TGF-β) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rb1 slows the aging process by regulating cell cycle, apoptotic pathway and metabolism of aging mice.
Mar 08, 2020
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2020 Mar 9 ;255:112746. Epub 2020 Mar 9. PMID:
32165173
Article Published Date
: Mar 08, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Aging
Pharmacological Actions
:
Anti-Apoptotic
[+]
Ginsenoside Rb1 stimulates adiponectin signaling in C2C12 muscle cells.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2015 Jan ;53(1):125-32. Epub 2014 Oct 14. PMID:
25311947
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Adiponectin: Low Levels
,
Diabetic Complications
Pharmacological Actions
:
Adiponectin upregulation
,
Hypoglycemic Agents
[+]
Ginsenoside Rb1 suppresses AOM/DSS-induced colon carcinogenesis.
Jan 18, 2023
Click here to read the entire abstract
Pubmed Data
: Anticancer Agents Med Chem. 2023 Jan 19. Epub 2023 Jan 19. PMID:
36655530
Article Published Date
: Jan 18, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
Gastrointestinal Agents
[+]
Ginsenoside Rb1, salvianolic acid B and their combination modulate gut microbiota and improve glucolipid metabolism in high-fat diet induced obese mice.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PeerJ. 2021 ;9:e10598. Epub 2021 Feb 3. PMID:
33604164
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
High Fat Diet
,
Obesity
Pharmacological Actions
:
Gastrointestinal Agents
Additional Keywords
:
Anti-Obesity Agents
[+]
Ginsenoside Rb1produces pain antihypersensitivity by spinal microglial dynorphin A expression.
Nov 07, 2022
Click here to read the entire abstract
Pubmed Data
: Neurosci Res. 2022 Nov 8. Epub 2022 Nov 8. PMID:
36368461
Article Published Date
: Nov 07, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Neuropathic Pain
Pharmacological Actions
:
Analgesics
[+]
Ginsenoside Rb3 ameliorates myocardial ischemia-reperfusion injury in rats.
Aug 31, 2011
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2011 Sep ;49(9):900-6. Epub 2011 May 19. PMID:
21591990
Article Published Date
: Aug 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Ginsenoside Rb3 could alleviate cisplatin-evoked toxic effects on kidney cells.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2021 ;2021:6640714. Epub 2021 Jan 16. PMID:
33510805
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Apoptotic
,
Chemoprotective Agents
[+]
Ginsenoside Rb3 possesses the effect against isoproterenol-induced myocardial injury and heart function impairment.
Jun 24, 2010
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2010 Jun 25 ;636(1-3):121-5. Epub 2010 Apr 2. PMID:
20371232
Article Published Date
: Jun 24, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Isoproterenol
[+]
Ginsenoside Rb3 protects cardiomyocytes against ischemia-reperfusion injury.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2014 ;9(8):e103628. Epub 2014 Aug 1. PMID:
25084093
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
,
NF-kappaB Inhibitor
[+]
Ginsenoside Rb3 provides protective effects against cisplatin-induced nephrotoxicity.
May 15, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Prolif. 2019 May 16:e12627. Epub 2019 May 16. PMID:
31094028
Article Published Date
: May 15, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Ginsenoside Rc ameliorated atherosclerosis via regulating gut microbiota and fecal metabolites.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:990476. Epub 2022 Sep 15. PMID:
36188559
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Atherosclerosis
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Ginsenoside Rc attenuates DSS-induced ulcerative colitis, intestinal inflammatory, and barrier function.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:1000444. Epub 2022 Oct 28. PMID:
36386150
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
[+]
Ginsenoside Rc attenuates myocardial ischaemic injury through antioxidative and anti-inflammatory effects.
Nov 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2022 Dec ;60(1):1038-1046. PMID:
35634656
Article Published Date
: Nov 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
[+]
Ginsenoside Rc promotes bone formation in ovariectomy-induced osteoporosis.
May 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2022 May 31 ;23(11). Epub 2022 May 31. PMID:
35682866
Article Published Date
: May 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Osteoporosis
Pharmacological Actions
:
Osteoprotective
Additional Keywords
:
Ovariectomy-Induced Changes
[+]
Ginsenoside Rc, as an FXR activator, alleviates acetaminophen-induced hepatotoxicity.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:1027731. Epub 2022 Oct 7. PMID:
36278209
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Ginsenoside Rd ameliorates high fat diet-induced obesity.
Mar 31, 2020
Click here to read the entire abstract
Pubmed Data
: Obesity (Silver Spring). 2020 Apr ;28(4):783-792. Epub 2020 Mar 6. PMID:
32144882
Article Published Date
: Mar 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
High Fat Diet
,
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Ginsenoside Rd ameliorates high glucose-induced retinal endothelial injury through AMPK-STRT1 interdependence.
Feb 08, 2022
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2022 Feb 9:106123. Epub 2022 Feb 9. PMID:
35150861
Article Published Date
: Feb 08, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetic Retinopathy
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Ginsenoside Rd ameliorates muscle wasting.
Sep 19, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cachexia Sarcopenia Muscle. 2022 Sep 20. Epub 2022 Sep 20. PMID:
36127129
Article Published Date
: Sep 19, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cachexia
Pharmacological Actions
:
Anti-Cachexic Agents
,
Antioxidants
,
STAT3 Inhibitor
[+]
Ginsenoside Rd attenuated hyperglycemia.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Curr Res Food Sci. 2023 ;6:100491. Epub 2023 Mar 21. PMID:
37033737
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Hyperglycemia
Pharmacological Actions
:
Hypoglycemic Agents
[+]
Ginsenoside Rd attenuates beta-amyloid-induced tau phosphorylation.
May 31, 2013
Click here to read the entire abstract
Pubmed Data
: Neurobiol Dis. 2013 Jun ;54:320-8. Epub 2013 Jan 13. PMID:
23321003
Article Published Date
: May 31, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rd attenuates blood-brain barrier damage by suppressing proteasome-mediated signaling after transient forebrain ischemia.
Mar 11, 2020
Click here to read the entire abstract
Pubmed Data
: Neuroreport. 2020 Mar 12. Epub 2020 Mar 12. PMID:
32168101
Article Published Date
: Mar 11, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Ischemia
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Blood Brain Barrier
[+]
Ginsenoside Rd attenuates cerebral ischemia/reperfusion injury.
Feb 02, 2022
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2022 Feb 3 ;105:108582. Epub 2022 Feb 3. PMID:
35124564
Article Published Date
: Feb 02, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
MicroRNA modulator
,
Neuroprotective Agents
,
Nrf2 activation
[+]
Ginsenoside Rd contributes the attenuation of cardiac hypertrophy in vivo and in vitro.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2019 Jan ;109:1016-1023. Epub 2018 Nov 6. PMID:
30551351
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cardiac Hypertrophy
Pharmacological Actions
:
Cardioprotective
[+]
Ginsenoside Rd could be a promising agent for amelioration of neuroimmune dysfunction diseases such as multiple sclerosis.
Aug 31, 2014
Click here to read the entire abstract
Pubmed Data
: J Neurosci Res. 2014 Sep ;92(9):1217-26. Epub 2014 May 2. PMID:
24798871
Article Published Date
: Aug 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Multiple Sclerosis
Pharmacological Actions
:
Brain-derived neurotrophic factor modulator
,
Interleukin-4 downregulation
[+]
Ginsenoside Rd exhibits significant antidepressant-like effect and that HIF-1α signaling pathway is a promising target for the treatment of depression.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2022 ;16:843-861. Epub 2022 Mar 28. PMID:
35370402
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
[+]
Ginsenoside Rd has the potential to be developed as a promising medication in the control and prevention of periodontitis.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Cell Infect Microbiol. 2022 ;12:813953. Epub 2022 Apr 11. PMID:
35480231
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
,
Periodontitis
Pharmacological Actions
:
Anti-Bacterial Agents
,
Anti-Inflammatory Agents
[+]
Ginsenoside Rd inhibited ferroptosis to alleviate CCl4-induced acute liver injury.
Nov 27, 2022
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2022 Nov 28:1-15. Epub 2022 Nov 28. PMID:
36437551
Article Published Date
: Nov 27, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Ginsenoside Rd inhibits apoptosis following spinal cord ischemia/reperfusion injury.
Sep 14, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neural Regen Res. 2014 Sep 15 ;9(18):1678-87. PMID:
25374589
Article Published Date
: Sep 14, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Ischemia
,
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Ginsenoside Rd inhibits the expressions of iNOS and COX-2 by suppressing NF-κB.
Feb 28, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2013 Mar ;37(1):54-63. PMID:
23717157
Article Published Date
: Feb 28, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Ginsenoside Rd may be a promising anti-angiogenic drug with significant antitumor activity in human breast cancer.
Jun 30, 2017
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2017 Jul ;38(1):359-367. Epub 2017 May 19. PMID:
28534996
Article Published Date
: Jun 30, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-Angiogenic
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Dose Response
[+]
Ginsenoside Rd pretreatment may be a promising treatment to prevent ischemia-reperfusion injury.
Sep 15, 2022
Click here to read the entire abstract
Pubmed Data
: Braz J Cardiovasc Surg. 2022 Sep 16. Epub 2022 Sep 16. PMID:
36112741
Article Published Date
: Sep 15, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rd reverses cognitive deficits by modulating BDNF-dependent CREB pathway in chronic restraint stress.
Jul 15, 2020
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2020 Jul 16 ;258:118107. Epub 2020 Jul 16. PMID:
32682919
Article Published Date
: Jul 15, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Brain-derived neurotrophic factor modulator
,
Neuroprotective Agents
[+]
Ginsenoside Rd therapy improves histological and functional recovery in a model of inflammatory bowel disease.
May 27, 2020
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2020 May 28. Epub 2020 May 28. PMID:
32468636
Article Published Date
: May 27, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammatory Bowel Diseases
Pharmacological Actions
:
Gastrointestinal Agents
Problem Substances
:
Indomethacin
[+]
Ginsenoside Re and Rk3 could improve the hematopoietic function of myelosuppressed mice.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2019 Oct ;43(4):618-624. Epub 2018 Aug 30. PMID:
31695568
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Chemoprotective Agents
[+]
Ginsenoside Re attenuates memory impairments.
Jul 14, 2022
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2022 Jul 15 ;189:2-19. Epub 2022 Jul 15. PMID:
35840016
Article Published Date
: Jul 14, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Memory Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Re attenuates myocardial ischemia/reperfusion induced ferroptosis.
Apr 30, 2023
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2023 May ;113:154681. Epub 2023 Jan 30. PMID:
36893674
Article Published Date
: Apr 30, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Cardioprotective
[+]
Ginsenoside Re could be used to improve high fat diet induced insulin resistance.
Mar 16, 2017
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2017 Mar 17. Epub 2017 Mar 17. PMID:
28314104
Article Published Date
: Mar 16, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cognitive Decline/Dysfunction
,
High Fat Diet
,
Insulin Resistance
Pharmacological Actions
:
Anticholesteremic Agents
,
Antioxidants
,
Hypoglycemic Agents
,
Hypolipidemic
[+]
Ginsenoside Re inhibits cardiomyocyte apoptosis
Dec 31, 2001
Click here to read the entire abstract
Pubmed Data
: J Huazhong Univ Sci Technolog Med Sci. 2002 ;22(4):305-9. PMID:
12674765
Article Published Date
: Dec 31, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Ginsenoside Re inhibits myocardial fibrosis.
Feb 28, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2023 Mar ;47(2):218-227. Epub 2021 Dec 2. PMID:
36926602
Article Published Date
: Feb 28, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Fibrosis
Pharmacological Actions
: