Goji

Name	AC	CK
Oxidative Stress	34	86
Inflammation	19	40
Cardiovascular Diseases	6	36
Nonalcoholic fatty liver disease (NAFLD)	7	33
Hyperlipidemia	3	23
Alzheimer's Disease	14	21
High Fat Diet	10	20
Colitis	9	18
Aging	8	15
Obesity	7	14
Rheumatoid Arthritis	4	14
Macular Degeneration	4	13
Retinitis Pigmentosa	3	13
Alcohol Toxicity	7	12
Breast Cancer	7	12
Depression	2	12
Periodontitis	2	12
Ulcerative Colitis	6	12
Diabetic Retinopathy	8	11
Athletic Performance	1	10
Chronic Obstructive Pulmonary Disease	1	10
Diabetic Complications	5	10
High Cholesterol	1	10
Immune Disorders: Low Immune Function	1	10
Liver Damage	5	10
Mood Disorders	1	10
Myocardial Ischemia	5	10
Phthalate Toxicity	5	10
Testicular Injury: Chemical/Metal Induced	5	10
Lipopolysaccharide-Induced Toxicity	5	9
Alcoholic Liver Disease	4	8
Eye Damage	3	8
Ultraviolet Radiation Induced Damage	5	8
Liver Cancer	6	7
Radiation	4	7
Sepsis	3	7
Blue Light Toxicity	2	6
Brain Inflammation	4	6
Cerebral Ischemia	3	6
Chemically-Induced Liver Damage	3	6
Dysbiosis	3	6
High Fructose Diet	3	6
Hyperglycemia	3	6
Parkinson's Disease	4	6
Diabetes Mellitus: Type 2	3	5
Glaucoma	4	5
Osteoporosis	3	5
Acrylamide-induced toxicity	2	4
Air Pollution Linked Toxicity	2	4
Anxiety	2	4
Cadmium Poisoning	2	4
Cognitive Decline/Dysfunction	2	4
Colorectal Cancer	2	4
Gastric Ulcer	2	4
Heart Failure	2	4
Hydrogen Peroxide Induced Toxicity	4	4
Hyperuricemia	2	4
Hypoxia	2	4
Infertility: Male	2	4
Inflammatory Bowel Diseases	3	4
Lung Injury: Acute	2	4
Metabolic Diseases	2	4
Sarcopenia	2	4
Aging Skin	2	3
Aspirin-Induced Toxicity	2	3
Brain: Oxidative Stress	2	3
Diabetes Mellitus: Type 1	2	3
Fatigue	2	3
Influenza A	2	3
Ischemia	1	3
Multiple Sclerosis	1	3
Neurodegenerative Diseases	2	3
Osteoarthritis	2	3
Retinal Diseases	2	3
Aging: Brain	1	2
Aging: Heart	1	2
Arteriosclerosis	1	2
Asthma	1	2
Autoimmune Diseases	1	2
Cancers: All	2	2
Cardiomyopathy	1	2
Chemotherapy	1	2
Chemotherapy and Radiation Toxicity	1	2
Chemotherapy-Induced Toxicity	1	2
Chemotherapy-Induced Toxicity: Cyclophosphamide	1	2
Chemotherapy-Induced Toxicity: Doxorubicin	2	2
Colon Cancer	2	2
DNA damage	1	2
Degenerative Disk Disease	1	2
Diabetes Mellitus: Type 2: Prevention	1	2
Diabetes: Eye Disease	1	2
Diabetic Nephropathy	1	2
Dry Eye Syndromes	1	2
Endothelial Dysfunction	2	2
Erectile Dysfunction	1	2
Gastrointestinal Inflammation	1	2
Hepatic Encephalopathy	1	2
Huntington Disease	1	2
Hypercholesterolemia	1	2
Hypertension	1	2
Infertility: Female	1	2
Intracerebral Hemorrhage	1	2
Intraocular hypertension	1	2
Kidney Damage	1	2
Kidney Damage: Chemically-Induced	1	2
Lead Poisoning	1	2
Leukopenia	1	2
Mitochondrial Dysfunction	1	2
Muscle Atrophy	1	2
Myocardial Infarction	1	2
Nephritis	1	2
Neuromyelitis Optica	1	2
Ocular Hypertension	1	2
Prenatal Nutrition: Learning/Intelligence of Offspring	1	2
Prostatitis: Chronic	1	2
Pseudomonas aeruginosa	1	2
Sciatic Nerve Crush Injury	1	2
Sjogren's Syndrome	1	2
Stroke	1	2
Stroke: Ischemic	1	2
Sunburn	1	2
Surgery: Anesthesiology	1	2
Testicular Injury: Cadmium-Induced	1	2
Thrombocytopenia	1	2
Tuberculosis Drug Induced Toxicity	1	2
Vitiligo	1	2
Wound Healing	1	2
Aging: Immunosenecence	1	1
Aspergillosis	1	1
Atopic Dermatitis	1	1
Bladder Cancer	1	1
Cervical Cancer	1	1
Chemotherapy-Induced Toxicity: Oxaliplatin	1	1
Coronavirus Disease (Covid-19)	1	1
Diabetes: Cataract	1	1
Escherichia coli Infections	1	1
Excitotoxicity	1	1
Gastric Cancer	1	1
Glioblastoma	1	1
Head and Neck Cancer	1	1
High Homocysteine	1	1
Human Papillomavirus (HPV)	1	1
Immunodeficiency: Common Variable	1	1
Lipid Peroxidation	1	1
Lung Cancer	1	1
Mastitis	1	1
Mercury Poisoning	1	1
Mycotoxin Toxicity	1	1
Neuroblastoma	1	1
Oral Cancer	1	1
Oral Mucositis	1	1
Pancreatic Cancer	1	1
Prostate Cancer	1	1
Skin Cancer	1	1
Spinal Cord Injuries	1	1
Staphylococcus aureus infection	1	1
Stroke: Attenuation/Recovery	1	1

Name	AC	CK
Antioxidants	73	169
Anti-Inflammatory Agents	62	122
Gastrointestinal Agents	39	74
Neuroprotective Agents	37	72
Hepatoprotective	23	62
Tumor Necrosis Factor (TNF) Alpha Inhibitor	32	61
Anti-Apoptotic	30	53
Cardioprotective	12	51
Interleukin-6 Downregulation	23	45
Hypolipidemic	10	44
Immunomodulatory	15	40
Interleukin-1 beta downregulation	20	40
NF-kappaB Inhibitor	10	21
Nrf2 activation	13	21
Antiproliferative	16	18
MicroRNA modulator	6	18
Apoptotic	12	16
Interleukin-10 upregulation	7	13
Superoxide Dismutase Up-regulation	7	13
Immunomodulatory: Th17 downregulation	2	12
Malondialdehyde Down-regulation	6	12
Heme oxygenase-1 up-regulation	7	11
Gastroprotective	6	10
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	1	10
Hypoglycemic Agents	5	9
Photoprotective	5	9
Chemopreventive	4	8
Cytoprotective	6	8
Renoprotective	4	8
Radioprotective	4	7
Fertility Agents: Male	3	6
Interleukin-18 down-regulation	3	6
Tumor Suppressor Protein p53 Upregulation	3	6
Alpha-glucosidase inhibitor	2	4
Anti-Anxiety Agents	2	4
Anti-metastatic	4	4
Cyclooxygenase 2 Inhibitors	2	4
P21 Activation	2	4
Xanthine oxidase inhibitor	2	4
Angiogenesis Inhibitors	2	3
Chemoprotective Agents	3	3
Interleukin-8 downregulation	2	3
Matrix metalloproteinase-9 (MMP-9) inhibitor	2	3
Neurogenesis	2	3
Nitric Oxide Inhibitor	2	3
Anti-Angiogenic	1	2
Anti-Fibrotic	1	2
Antidepressive Agents	1	2
Antihypertensive Agents	1	2
Antioxidant Effects	1	2
Antiviral Agents	2	2
Autophagy Up-regulation	1	2
Cell cycle arrest	2	2
Chemosensitizer	2	2
Chemotherapeutic	2	2
Chondroprotective	1	2
Fertility Agents: Female	1	2
Interleukin-12 downregulation	1	2
Interleukin-4 upregulation	1	2
Neuroplasticity enhancement	1	2
Osteoprotective	1	2
Prophylactic Agents	1	2
Uricosuric Agents	1	2
Acetylcholinesterase Inhibitor	1	1
Alpha-amylase inhibitor	1	1
Anti-Bacterial Agents	1	1
Antimicrobial	1	1
Catalase Up-Regulation	1	1
Immunostimulatory	1	1

[+]

Cardiovascular disease risk reduction with wolfberry consumption.Nov 26, 2021

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Pubmed Data : Eur J Nutr. 2021 Nov 27. Epub 2021 Nov 27. PMID: 34839399

Article Published Date : Nov 26, 2021

Study Type : Meta Analysis, Review

Additional Links

Substances : Goji

Diseases : Cardiovascular Diseases

Pharmacological Actions : Cardioprotective

Additional Keywords : Risk Reduction

[+]

The effect of Lycium barbarum polysaccharide on the glucose and lipid metabolism.Jul 01, 2021

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Pubmed Data : J Am Coll Nutr. 2021 Jul 2:1-9. Epub 2021 Jul 2. PMID: 34213407

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Pubmed Data : F1000Res. 2023 ;12:302. Epub 2024 Nov 26. PMID: 39640061

Article Published Date : Dec 31, 2022

Study Type : Human Study

Additional Links

Substances : Goji

Diseases : Periodontitis

Pharmacological Actions : Antioxidants

Additional Keywords : Mouthwash

[+]

Goji berry supplementation may be of therapeutic value in macular degeneration. Feb 01, 2011

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Pubmed Data : Optom Vis Sci. 2011 Feb ;88(2):257-62. PMID: 21169874

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Pubmed Data : Int J Chron Obstruct Pulmon Dis. 2020 ;15:1997-2004. Epub 2020 Aug 24. PMID: 32921997

Article Published Date : Dec 31, 2019

Study Type : Human Study

Additional Links

Substances : Goji

Diseases : Chronic Obstructive Pulmonary Disease

Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

[+]

Supplementation of Lycium barbarum polysaccharide combined with aerobic exercise ameliorates high-fat-induced nonalcoholic steatohepatitis.Aug 07, 2022

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Pubmed Data : Nutrients. 2022 Aug 8 ;14(15). Epub 2022 Aug 8. PMID: 35956423

Article Published Date : Aug 07, 2022

Hypoglycaemic activity of the anthocyanin enriched fraction of Lycium ruthenicum fruits.Dec 14, 2024

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Pubmed Data : Food Chem. 2024 Dec 15 ;461:140837. Epub 2024 Aug 10. PMID: 39151350

Article Published Date : Dec 14, 2024

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Anthocyanins, Goji

Diseases : Hyperglycemia

Pharmacological Actions : Alpha-glucosidase inhibitor , Hypoglycemic Agents

Additional Keywords : Plant Extracts

[+]

Inhibition of iron death by Lycium barbarum polysaccharides ameliorates myocardial injury in sepsis.Aug 31, 2025

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Pubmed Data : Curr Res Food Sci. 2025 ;10:100955. Epub 2024 Dec 14. PMID: 39807359

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Pubmed Data : Int J Mol Sci. 2022 Feb 22 ;23(5). Epub 2022 Feb 22. PMID: 35269566

Article Published Date : Feb 21, 2022

Study Type : Animal Study

Additional Links

Substances : Capsaicin, Goji

Diseases : Oxidative Stress, Ulcerative Colitis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Polysaccharides

[+]

Ameliorative potentials of the ethanolic extract from Lycium chinense leaf extract against diabetic cardiomyopathy.Sep 30, 2022

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Pubmed Data : Biomed Pharmacother. 2022 Oct ;154:113583. Epub 2022 Aug 19. PMID: 35994819

Article Published Date : Sep 30, 2022

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Cardiomyopathy, Diabetic Complications

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

An acidic polysaccharide from Lycium barbarum L: Isolation, purification, structural characterization, and therapeutic effects on ulcerative colitis.Jul 31, 2025

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Pubmed Data : Int J Biol Macromol. 2025 Aug ;319(Pt 4):145602. Epub 2025 Jun 26. PMID: 40581006

Anxiolytic, antioxidant, and neuroprotective effects of goji berry polysaccharides in ovariectomized rats.Dec 31, 2019

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Pubmed Data : Front Nutr. 2022 ;9:929776. Epub 2022 Jul 8. PMID: 35898713

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Pubmed Data : World J Mens Health. 2016 Dec 22. Epub 2016 Dec 22. PMID: 28064475

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Pubmed Data : Zhong Yao Cai. 2015 Jul ;38(7):1454-9. PMID: 26946843

Article Published Date : Jun 30, 2015

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Cerebral Ischemia

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

Additional Keywords : Polysaccharides

[+]

Goji polysaccharide has attenuated oxidative stress and inflammation to show antidiabetic and antinephritic effects.Dec 31, 2015

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Pubmed Data : Biomed Res Int. 2016 ;2016:4147879. Epub 2016 May 26. PMID: 27314019

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Chemotherapy and Radiation Toxicity, Oxidative Stress

Pharmacological Actions : Radioprotective

Anti Therapeutic Actions : Low Dose Ionizing Radiation

[+]

Goji signficantly enhances peripheral platelet and white blood cell counts in irradiation and chemotherapy-induced myelosuppressive mice. Apr 01, 2005

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Pubmed Data : Cancer Biother Radiopharm. 2005 Apr;20(2):155-62. PMID: 15869449

Article Published Date : Apr 01, 2005

Study Type : Animal Study

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Substances : Goji

Diseases : Chemotherapy-Induced Toxicity, Leukopenia, Thrombocytopenia

[+]

Hepatoprotection of Lycii fructus polysaccharide against oxidative stress.Dec 31, 2020

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Pubmed Data : Oxid Med Cell Longev. 2021 ;2021:3923625. Epub 2021 Feb 18. PMID: 33680282

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Liver Damage, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Hepatoprotective

Additional Keywords : Polysaccharides

[+]

Hypoglycemic effects of Lycium barbarum polysaccharide in type 2 diabetes mellitus.Dec 31, 2021

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Pubmed Data : Front Nutr. 2022 ;9:916271. Epub 2022 Jun 30. PMID: 35845787

Pubmed Data : Cell Signal. 2025 Sep 6 ;136:112114. Epub 2025 Sep 6. PMID: 40921308

Article Published Date : Sep 05, 2025

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Degenerative Disk Disease

[+]

Lycium barbarum ameliorates neural damage induced by experimental ischemic stroke and radiation exposure.Feb 23, 2023

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Pubmed Data : Front Biosci (Landmark Ed). 2023 Feb 24 ;28(2):38. PMID: 36866558

Article Published Date : Feb 23, 2023

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Brain Inflammation , Radiation, Stroke

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

[+]

Lycium barbarum and Lactobacillus acidophilus synergistically protect against anti-tuberculosis drug-induced male reproductive injury.Dec 31, 2024

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[+]

Lycium barbarum polysaccharide improves dopamine metabolism and symptoms in an MPTP-induced model of Parkinson's disease.Oct 27, 2022

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Pubmed Data : Ecotoxicol Environ Saf. 2025 Apr 15 ;295:118148. Epub 2025 Apr 6. PMID: 40188734

Article Published Date : Apr 14, 2025

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Cadmium Poisoning , Osteoporosis

Pharmacological Actions : Antioxidants, Autophagy Up-regulation

Additional Keywords : Polysaccharides

Problem Substances : Cadmium

[+]

Lycium barbarum polysaccharide protects cardiomyocytes from hypoxia/reoxygenation injury.Jan 30, 2023

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Pubmed Data : Life Sci. 2019 Dec 28:117240. Epub 2019 Dec 28. PMID: 31891722

Article Published Date : Dec 27, 2019

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Kidney Damage, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Renoprotective

[+]

Lycium barbarum polysaccharides attenuates the apoptosis of hippocampal neurons induced by sevoflurane.Aug 31, 2018

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Pubmed Data : Exp Ther Med. 2018 Sep ;16(3):1834-1840. Epub 2018 Jul 9. PMID: 30186408

Article Published Date : Aug 31, 2018

Study Type : Animal Study

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Substances : Goji

Diseases : Surgery: Anesthesiology

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

Additional Keywords : Polysaccharides

[+]

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Pubmed Data : Clin Oral Investig. 2025 Apr 3 ;29(4):219. Epub 2025 Apr 3. PMID: 40175831

Article Published Date : Apr 02, 2025

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Periodontitis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Matrix metalloproteinase-9 (MMP-9) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Mechanisms of action of Lycium barbarum polysaccharide in protecting against vitiligo.Nov 30, 2023

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Pubmed Data : Photochem Photobiol Sci. 2010 Apr 31;9(4):601-607. PMID: 20354657

Article Published Date : Apr 30, 2010

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Sunburn

Pharmacological Actions : Antioxidants

[+]

Polysaccharide-rich hydrogel formulation combined with photobiomodulation repairs UV-induced photodamage in mice skin.Aug 31, 2020

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Pubmed Data : Wound Repair Regen. 2020 Sep ;28(5):645-655. Epub 2020 Jun 26. PMID: 32590890

Article Published Date : Aug 31, 2020

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Ultraviolet Radiation Induced Damage, Wound Healing

Therapeutic Actions : Photobiomodulation

Additional Keywords : Polysaccharides, Skin Rejuvenation

[+]

Polysaccharides from Lycium barbarum ameliorate amyloid pathology and cognitive functions.Nov 08, 2019

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Pubmed Data : Biol Trace Elem Res. 2025 Apr 27. Epub 2025 Apr 27. PMID: 40287904

Article Published Date : Apr 26, 2025

Study Type : Animal Study

Additional Links

Substances : Goji, Selenium

Diseases : Testicular Injury: Cadmium-Induced

Pharmacological Actions : Antioxidants

Additional Keywords : Polysaccharides

Problem Substances : Cadmium

[+]

Protective effect of Lycium ruthenicum polyphenols on oxidative stress against acrylamide induced liver injury.Jun 24, 2022

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Pubmed Data : Nutrients. 2021 Aug 25 ;13(9). Epub 2021 Aug 25. PMID: 34578823

Article Published Date : Aug 24, 2021

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Inflammation, Kidney Damage: Chemically-Induced, Lead Poisoning, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants

Problem Substances : Lead

[+]

Supplementation With Lycium barbarum polysaccharides reduce obesity in high-fat diet-fed mice by modulation of gut microbiota.Dec 31, 2020

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Pubmed Data : J Nutr Biochem. 2020 Sep ;83:108416. Epub 2020 May 17. PMID: 32554223

Article Published Date : Aug 31, 2020

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Aging: Brain , Inflammation, Oxidative Stress

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

These findings suggest that Lycium barbarum polysaccharide supplementation alleviates obesity by ameliorating lipid droplets accumulation.Jun 24, 2024

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Pubmed Data : Acta Biochim Biophys Sin (Shanghai). 2024 Jun 25 ;56(6):844-856. PMID: 38606478

Article Published Date : Jun 24, 2024

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Obesity

Pharmacological Actions : Hypolipidemic

Additional Keywords : Anti-Obesity Agents, Polysaccharides

[+]

These results indicated that Lycium barbarum polysaccharide possess antidepressant activities.Dec 31, 2018

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[+]

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Pubmed Data : Nutrients. 2022 Dec 1 ;14(23). Epub 2022 Dec 1. PMID: 36501143

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Pubmed Data : Exp Ther Med. 2016 Aug ;12(2):683-689. Epub 2016 Jun 2. PMID: 27446261

Article Published Date : Jul 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Goji

Diseases : Mercury Poisoning

Pharmacological Actions : Neurogenesis, Neuroprotective Agents

Additional Keywords : Hippocampus Regeneration, Neural Stem Cells

[+]

Hepatoprotective effect of crude polysaccharide isolated from Lycium barbarum L. against alcohol-induced oxidative damage.Nov 30, 2020

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Pubmed Data : Food Sci Nutr. 2020 Dec ;8(12):6528-6538. Epub 2020 Oct 29. PMID: 33312537

Article Published Date : Nov 30, 2020

Study Type : In Vitro Study

Additional Links

Substances : Goji

Diseases : Alcohol Toxicity

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hepatoprotective, Nrf2 activation

Additional Keywords : Polysaccharides

[+]

Immunomodulatory and antiviral effects of Lycium barbarum glycopeptide on influenza a virus infection.Feb 28, 2023

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Pubmed Data : J Pharm Anal. 2025 May ;15(5):101130. Epub 2024 Oct 28. PMID: 40496070

Article Published Date : Apr 30, 2025

Study Type : Review

Additional Links

Substances : Goji

Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2

Pharmacological Actions : Alpha-amylase inhibitor, Alpha-glucosidase inhibitor , Anti-Inflammatory Agents, Antioxidants, Immunomodulatory

[+]

Lycium barbarum berries as source of bioactive compounds for healthy purposes.Feb 28, 2023

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Lycium barbarum polysaccharide reverses drug resistance in oxaliplatin-resistant colon cancer cells.Dec 31, 2023

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Pubmed Data : Int J Mol Sci. 2020 Jun 30 ;21(13). Epub 2020 Jun 30. PMID: 32629957

Article Published Date : Jun 29, 2020

Study Type : In Vitro Study

Additional Links

Substances : Goji

Diseases : Macular Degeneration

Pharmacological Actions : Anti-Apoptotic

Additional Keywords : Polysaccharides

[+]

Lycium barbarum polysaccharides inhibit proliferation and migration of bladder cancer cells.Dec 14, 2016

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Protective effect and mechanism of lycium barbarum polysaccharide against UVB-induced skin photoaging.Sep 30, 2024

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Pubmed Data : Photochem Photobiol Sci. 2024 Oct ;23(10):1931-1943. Epub 2024 Oct 8. PMID: 39379645

Article Published Date : Sep 30, 2024

Study Type : In Vitro Study

Additional Links

Substances : Goji

Diseases : Aging Skin, Ultraviolet Radiation Induced Damage

Pharmacological Actions : Antioxidants, Photoprotective, Superoxide Dismutase Up-regulation

Additional Keywords : Polysaccharides

[+]

Protective functions of Lycium barbarum polysaccharides in H2O2-injured vascular endothelial cells.Oct 31, 2019

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Pubmed Data : Food Sci Nutr. 2022 Sep ;10(9):2956-2968. Epub 2022 Apr 18. PMID: 36171788

Article Published Date : Aug 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : Anthocyanins, Goji

Diseases : Colorectal Cancer

Pharmacological Actions : Antiproliferative

Additional Keywords : Natural Substance Synergy, Polysaccharides

[+]

Pubmed Data : Biomed Res Int. 2016 ;2016:7529521. Epub 2016 Nov 14. PMID: 27965980

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Goji

Diseases : Liver Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Chemopreventive

Additional Keywords : Gene Expression Regulation

[+]

Wolfberry (Lycium barbarum) glycopeptide attenuates dopaminergic neurons loss by inhibiting lipid peroxidation in Parkinson's disease.Dec 31, 2024

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Pubmed Data : Phytomedicine. 2025 Jan ;136:156275. Epub 2024 Nov 26. PMID: 39644762

Article Published Date : Dec 31, 2024

Study Type : In Vitro Study

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Substances : Goji

Diseases : Lipid Peroxidation, Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

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View the Evidence: 269 Abstracts with Goji Research

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Cardiovascular disease risk reduction with wolfberry consumption.Nov 26, 2021

The effect of Lycium barbarum polysaccharide on the glucose and lipid metabolism.Jul 01, 2021

An extract of Lycium barbarum mimics exercise to improve muscle endurance through increasing type IIa oxidative muscle fibers by activating ERRγ.Aug 31, 2020

Benefit of Lycium barbarum polysaccharide supplementation in patients with nonalcoholic fatty liver disease.Jul 31, 2025

Delay of cone degeneration in retinitis pigmentosa using a 12-month treatment with Lycium barbarum supplement.Mar 11, 2019

Effects of wolfberry consumption on the human plasma lipidome and its association with cardiovascular disease risk factors.Dec 31, 2023

Goji berry intake has antioxidative and anti-inflammatory effects in overweight and hypercholesterolemic subjects.Jan 17, 2017

Goji berry mouthwash was more effective than chlorhexidine in increasing the antioxidant levels in saliva.Dec 31, 2022

Goji berry supplementation may be of therapeutic value in macular degeneration. Feb 01, 2011

Goji improves sense of well-being, and other indicators of good health.May 01, 2008

Lycium barbarum polysaccharide corrects CCR9+ Th17/ Treg imbalance in patients with rheumatoid arthritis.Apr 30, 2025

Lycium barbarum polysaccharide inhibited hypoxia-inducible factor 1 in COPD patients.Dec 31, 2019

Supplementation of Lycium barbarum polysaccharide combined with aerobic exercise ameliorates high-fat-induced nonalcoholic steatohepatitis.Aug 07, 2022

The daily consumption of goji berry juice significantly increases several immunological responses and subjective feelings of general well-being without any adverse reactions.Oct 01, 2009

Wolfberry consumption with a healthy dietary pattern lowers oxidative stress in middle-aged and older adults.Apr 06, 2021

Goji berry extracts have chemopreventive potential in breast cancer treatment.Nov 01, 2015

Lycium barbarum polysaccharides promotes mitochondrial biogenesis and energy balance in a NAFLD cell model.Dec 06, 2021

Anti-apoptotic and anti-inflammatory effects of an ethanolic extract of Lycium chinense root against particulate matter 10-induced cell death and inflammation.Sep 21, 2022

Effects of Lycium barbarum polysaccharide on the activation of pathogenic CD4+ T cells in a mouse model of multiple sclerosis.Mar 24, 2025

Hypoglycaemic activity of the anthocyanin enriched fraction of Lycium ruthenicum fruits.Dec 14, 2024

Inhibition of iron death by Lycium barbarum polysaccharides ameliorates myocardial injury in sepsis.Aug 31, 2025

Lycium barbarum glycopeptide alleviates retinal inflammation.Jul 31, 2025

Lycium barbarum glycopeptide inhibits colorectal cancer cell proliferation.Jul 22, 2025

Lycium barbarum glycopeptide mitigates retinal ischemia-reperfusion injury.Jul 29, 2025

Lycium barbarum glycopeptide reduces inflammation and fibrosis in corneal injury.Jul 31, 2025

Protective effect and mechanism of Lycium ruthenicum Murray anthocyanins against retinal damage induced by blue light exposure.Jul 31, 2024

Protective effects of Lycium barbarum L. berry extracts against oxidative stress-induced damage of the retina of aging mouse and ARPE-19 cells.Dec 12, 2022

Wolfberry water extract attenuates blue light-emitting diode damage to ARPE-19 cells and mouse retina.Apr 30, 2023

A pectic polysaccharide from Lycium ruthenicum Murray alleviates dextran sulfate sodium-induced colitis in mice.Dec 31, 2024

A purified fraction of polysaccharides from the fruits of Lycium barbarum L. improves glucose homeostasis and intestinal barrier function.Jun 05, 2023

A wolfberry (goji) preparation prevents prenatal stress-induced cognitive impairment of offspring rats and inhibits oxidative damage and mitochondrial dysfunction. Feb 05, 2010

Administration of Lycium barbarum polysaccharides and capsaicin attenuate dextran sulfate sodium-induced ulcerative colitis symptoms.Feb 21, 2022

Ameliorative potentials of the ethanolic extract from Lycium chinense leaf extract against diabetic cardiomyopathy.Sep 30, 2022

An acidic polysaccharide from Lycium barbarum L: Isolation, purification, structural characterization, and therapeutic effects on ulcerative colitis.Jul 31, 2025

An arabinogalactan from Lycium barbarum attenuates DSS-induced chronic colitis.Oct 18, 2021

An arabinogalactan from Lycium barbarum mitigated DSS caused intestinal injury via inhibiting mucosal damage and regulating the gut microbiota disorder.Mar 14, 2025

Anthocyanins from Lycium ruthenicum could alleviate HFD-induced hypercholesterolemia.Mar 31, 2024

Anthocyanins from Lycium ruthenicum Murray ameliorated high-fructose diet-induced neuroinflammation.Feb 14, 2023

Anti-aging activities of an ethanolic extract of Lycium ruthenicum in Caenorhabditis elegans based on metabonomic analysis.Dec 31, 2024

Anti-colitis comparison of polysaccharides and anthocyanins extracted from black wolfberry.Apr 30, 2025

Anxiolytic, antioxidant, and neuroprotective effects of goji berry polysaccharides in ovariectomized rats.Dec 31, 2019

Aqueous extract of Lycium ruthenicum attenuates neuroinflammation in C57BL/6J mice induced by high-fat and high-fructose diet.Nov 25, 2024

Berry fruits presented antioxidant and anti-inflammatory activities in vitro and in vivo.Feb 29, 2016

Betaine, a component of Lycium chinense, enhances muscular endurance of mice and myogenesis of myoblasts.Aug 31, 2021

Black goji berry anthocyanins extend lifespan and enhance the antioxidant defenses.Mar 14, 2025

Black Lycium barbarum polysaccharide attenuates LPS-induced intestine damage.Dec 31, 2021

Carboxymethylated Lycium barbarum seed dreg dietary fiber alleviates high fat diet-induced hyperlipidemia.Jun 30, 2024

Combined Lycium babarum polysaccharides and C-phycocyanin increase gastric Bifidobacterium relative abundance and protect against gastric ulcer caused by aspirin.Jan 05, 2021

Dietary goji shapes the gut microbiota to prevent the liver injury induced by acute alcohol Intake.Dec 31, 2021

Dietary supplementation with goji berry enhances the immune response and reduces pathogenesis to influenza infection in mice.Jul 31, 2012

Dietary wolfberry upregulates carotenoid metabolic genes and enhances mitochondrial biogenesis in the retina of db/db diabetic mice.Mar 14, 2013

Differential regulatory effects of Lycium barbarum polysaccharide components in cyclophosphamide-treated immunosuppressed mice.Nov 30, 2025

Effects of Lycium barbarum glycopeptide on renal and testicular injury induced by di(2-ethylhexyl) phthalate.Mar 31, 2022

Evaluation of the anti-alzheimer activity of Lycium barbarum polysaccharide in Aβ1-42-induced neurotoxicity in rat model.Mar 25, 2025

Flavonoids from Lycium barbarum leaves attenuate obesity.Dec 31, 2021

Flavonoids from Lycium barbarum leaves exhibit anti-aging effects through the redox-modulation.Aug 02, 2022

Gastroprotective effect of Lycium barbarum polysaccharides and C-phycocyanin in rats with ethanol-induced gastric ulcer.Dec 14, 2020

Goji (lycopom barbarum) exhibits a neuroprotective effect against beta-amyloid peptide neurotoxicity.Aug 01, 2005

Goji berry leaf exerts a comparable effect against colitis and microbiota dysbiosis.Apr 02, 2023

Goji berry seed oil exhibits anti-atherosclerotic activity comparable to lovastatin. Jun 01, 2007

Goji exhibits therapeutic activity in an experimental model of hypertension. Jun 01, 1998

Goji extracts may have a positive effect to improve erectile function in an old-aged rat model.Dec 21, 2016

Goji fruit protects sciatic nerve function against crush injury in a model of diabetic stress.Jun 30, 2016

Goji inhibits the growth of estrogen receptor positive human breast cancer by favoring altering estradiol metabolism. Jan 01, 2009

Goji polysaccharide attenuates diabetic testicular dysfunction.Aug 01, 2018

Goji polysaccharide can exert functional recovery of memory and motor coordination deficits in cerebral ischemic injured mice.May 14, 2017

Goji polysaccharide can protect against focal cerebral ischemic reperfusion injury in mice.Jun 30, 2015

Goji polysaccharide has attenuated oxidative stress and inflammation to show antidiabetic and antinephritic effects.Dec 31, 2015

Goji polysaccharide may be potentially useful for treating Huntington's disease.Jul 31, 2016

Goji polysaccharides have protective effects on diabetic nephropathy.Jul 14, 2016

Goji polysaccharides showed a protective effect on BMNC against ionizing radiation-induced apoptosis and oxidative damage.Dec 31, 2015

Goji signficantly enhances peripheral platelet and white blood cell counts in irradiation and chemotherapy-induced myelosuppressive mice. Apr 01, 2005

View the Evidence:
269 Abstracts with Goji Research