Goji

Name	AC	CK
Oxidative Stress	12	36
Inflammation	6	19
Depression	2	12
Macular Degeneration	2	11
Athletic Performance	1	10
Chronic Obstructive Pulmonary Disease	1	10
High Cholesterol	1	10
Immune Disorders: Low Immune Function	1	10
Mood Disorders	1	10
Retinitis Pigmentosa	1	10
Diabetic Retinopathy	6	9
Alzheimer's Disease	6	8
Diabetic Complications	4	8
Breast Cancer	2	7
Alcohol Toxicity	4	6
Liver Cancer	5	6
Cerebral Ischemia	2	4
Gastric Ulcer	2	4
Heart Failure	2	4
Infertility: Male	2	4
Aging	2	3
Cardiovascular Diseases	2	3
Glaucoma	3	3
Hydrogen Peroxide Induced Toxicity	3	3
Aging: Brain	1	2
Alcoholic Liver Disease	1	2
Anxiety	1	2
Arteriosclerosis	1	2
Aspirin-Induced Toxicity	1	2
Asthma	1	2
Chemotherapy and Radiation Toxicity	1	2
Chemotherapy-Induced Toxicity	1	2
Colitis	1	2
Diabetes Mellitus: Type 1	1	2
Diabetes Mellitus: Type 2: Prevention	1	2
Diabetes: Eye Disease	1	2
Diabetic Nephropathy	1	2
Dysbiosis	1	2
Endothelial Dysfunction	2	2
Erectile Dysfunction	1	2
Hepatic Encephalopathy	1	2
High Fat Diet	1	2
High Fructose Diet	1	2
Huntington Disease	1	2
Hypertension	1	2
Hyperuricemia	1	2
Hypoxia	1	2
Inflammatory Bowel Diseases	2	2
Influenza A	1	2
Intraocular hypertension	1	2
Kidney Damage	1	2
Leukopenia	1	2
Liver Damage	1	2
Lung Injury: Acute	1	2
Mitochondrial Dysfunction	1	2
Myocardial Infarction	1	2
Myocardial Ischemia	1	2
Nephritis	1	2
Nonalcoholic fatty liver disease (NAFLD)	1	2
Obesity	1	2
Phthalate Toxicity	1	2
Prenatal Nutrition: Learning/Intelligence of Offspring	1	2
Retinal Diseases	1	2
Sciatic Nerve Crush Injury	1	2
Sepsis	1	2
Sunburn	1	2
Surgery: Anesthesiology	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Thrombocytopenia	1	2
Aging: Immunosenecence	1	1
Bladder Cancer	1	1
Brain Inflammation	1	1
Brain: Oxidative Stress	1	1
Cancers: All	1	1
Cervical Cancer	1	1
Colon Cancer	1	1
Diabetes: Cataract	1	1
Excitotoxicity	1	1
Gastric Cancer	1	1
High Homocysteine	1	1
Hyperglycemia	1	1
Immunodeficiency: Common Variable	1	1
Lung Cancer	1	1
Mercury Poisoning	1	1
Mycotoxin Toxicity	1	1
Neuroblastoma	1	1
Osteoarthritis	1	1
Pancreatic Cancer	1	1
Parkinson's Disease	1	1
Prostate Cancer	1	1
Skin Cancer	1	1
Spinal Cord Injuries	1	1
Stroke: Attenuation/Recovery	1	1

Name	AC	CK
Antioxidants	27	56
Neuroprotective Agents	15	33
Anti-Inflammatory Agents	13	30
MicroRNA modulator	5	17
Immunomodulatory	5	15
Tumor Necrosis Factor (TNF) Alpha Inhibitor	8	14
Anti-Apoptotic	9	12
Apoptotic	8	12
Gastrointestinal Agents	7	12
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	1	10
Hepatoprotective	5	9
Cardioprotective	4	8
Chemopreventive	4	8
Interleukin-6 Downregulation	5	8
Antiproliferative	7	7
Cytoprotective	5	7
NF-kappaB Inhibitor	4	7
Renoprotective	3	6
Fertility Agents: Male	2	4
Gastroprotective	2	3
Hypoglycemic Agents	2	3
Interleukin-1 beta downregulation	2	3
Neurogenesis	2	3
Nrf2 activation	2	3
Angiogenesis Inhibitors	1	2
Anti-Angiogenic	1	2
Anti-Anxiety Agents	1	2
Anti-metastatic	2	2
Antidepressive Agents	1	2
Hypolipidemic	1	2
Interleukin-10 upregulation	1	2
Interleukin-12 downregulation	1	2
Radioprotective	1	2
Uricosuric Agents	1	2
Xanthine oxidase inhibitor	1	2
Acetylcholinesterase Inhibitor	1	1
Cell cycle arrest	1	1
Chemoprotective Agents	1	1
Chemotherapeutic	1	1
Immunostimulatory	1	1
Interleukin-8 downregulation	1	1
Matrix metalloproteinase-9 (MMP-9) inhibitor	1	1
Nitric Oxide Inhibitor	1	1
P21 Activation	1	1
Tumor Suppressor Protein p53 Upregulation	1	1

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Cardiovascular disease risk reduction with wolfberry consumption.Nov 26, 2021

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Pubmed Data : Eur J Nutr. 2021 Nov 27. Epub 2021 Nov 27. PMID: 34839399

Article Published Date : Nov 26, 2021

Study Type : Meta Analysis, Review

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Substances : Goji

Diseases : Cardiovascular Diseases

Pharmacological Actions : Cardioprotective

Additional Keywords : Risk Reduction

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The effect of Lycium barbarum polysaccharide on the glucose and lipid metabolism.Jul 01, 2021

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Pubmed Data : J Am Coll Nutr. 2021 Jul 2:1-9. Epub 2021 Jul 2. PMID: 34213407

Additional Keywords : Polysaccharides

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Dietary goji shapes the gut microbiota to prevent the liver injury induced by acute alcohol Intake.Dec 31, 2021

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Pubmed Data : Front Nutr. 2022 ;9:929776. Epub 2022 Jul 8. PMID: 35898713

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Pubmed Data : World J Mens Health. 2016 Dec 22. Epub 2016 Dec 22. PMID: 28064475

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Pubmed Data : Zhong Yao Cai. 2015 Jul ;38(7):1454-9. PMID: 26946843

Article Published Date : Jun 30, 2015

Study Type : Animal Study

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Substances : Goji

Diseases : Cerebral Ischemia

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

Additional Keywords : Polysaccharides

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Goji polysaccharide has attenuated oxidative stress and inflammation to show antidiabetic and antinephritic effects.Dec 31, 2015

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Pubmed Data : Biomed Res Int. 2016 ;2016:4147879. Epub 2016 May 26. PMID: 27314019

Article Published Date : Dec 31, 2015

Study Type : Animal Study

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Substances : Goji

Diseases : Chemotherapy and Radiation Toxicity, Oxidative Stress

Pharmacological Actions : Radioprotective

Anti Therapeutic Actions : Low Dose Ionizing Radiation

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Goji signficantly enhances peripheral platelet and white blood cell counts in irradiation and chemotherapy-induced myelosuppressive mice. Apr 01, 2005

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Pubmed Data : Int J Biol Macromol. 2021 May 13 ;183:1379-1392. Epub 2021 May 13. PMID: 33992651

Article Published Date : May 12, 2021

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Inflammation, Nonalcoholic fatty liver disease (NAFLD)

Therapeutic Actions : Exercise: Aerobic

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Hepatoprotective

Additional Keywords : Polysaccharides

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Lycium barbarum polysaccharides and Wolfberry juice prevent DEHP-induced hepatotoxicity.Feb 05, 2021

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Pubmed Data : Molecules. 2021 Feb 6 ;26(4). Epub 2021 Feb 6. PMID: 33562043

Article Published Date : Feb 05, 2021

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Chemically-Induced Liver Damage, Phthalate Toxicity

Pharmacological Actions : Hepatoprotective

Additional Keywords : Polysaccharides

Problem Substances : Phthalates

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Lycium barbarum polysaccharides attenuate kidney injury in sepsis.Dec 27, 2019

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Pubmed Data : Life Sci. 2019 Dec 28:117240. Epub 2019 Dec 28. PMID: 31891722

Article Published Date : Dec 27, 2019

Study Type : Animal Study

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Substances : Goji

Diseases : Kidney Damage, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Renoprotective

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Lycium barbarum polysaccharides attenuates the apoptosis of hippocampal neurons induced by sevoflurane.Aug 31, 2018

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Pubmed Data : Exp Ther Med. 2018 Sep ;16(3):1834-1840. Epub 2018 Jul 9. PMID: 30186408

Article Published Date : Aug 31, 2018

Study Type : Animal Study

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Substances : Goji

Diseases : Surgery: Anesthesiology

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

Additional Keywords : Polysaccharides

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Lycium barbarum polysaccharides protects H9c2 cells from hypoxia-induced injury.Jan 31, 2019

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Pubmed Data : Int J Biol Macromol. 2019 Nov 9. Epub 2019 Nov 9. PMID: 31715236

Article Published Date : Nov 08, 2019

Study Type : Transgenic Animal Study

Additional Links

Substances : Goji

Diseases : Alzheimer's Disease

Pharmacological Actions : Neurogenesis, Neuroprotective Agents

Additional Keywords : Polysaccharides

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Post-treatment intervention with Lycium Barbarum polysaccharides is neuroprotective in a rat model of chronic ocular hypertension.Oct 31, 2019

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Pubmed Data : Invest Ophthalmol Vis Sci. 2019 Nov 1 ;60(14):4606-4618. PMID: 31756254

Article Published Date : Oct 31, 2019

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Intraocular hypertension

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Polysaccharides

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Prebiotic, immuno-stimulating and gut microbiota-modulating effects of Lycium barbarum polysaccharide.Dec 31, 2019

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Pubmed Data : Nutrients. 2021 Aug 25 ;13(9). Epub 2021 Aug 25. PMID: 34578823

Article Published Date : Aug 24, 2021

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Inflammation, Kidney Damage: Chemically-Induced, Lead Poisoning, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants

Problem Substances : Lead

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Supplementation With Lycium barbarum polysaccharides reduce obesity in high-fat diet-fed mice by modulation of gut microbiota.Dec 31, 2020

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Pubmed Data : Front Microbiol. 2021 ;12:719967. Epub 2021 Aug 26. PMID: 34512598

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : High Fat Diet, Obesity

Pharmacological Actions : Gastroprotective

Additional Keywords : Polysaccharides

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Activation of Sirtuin1 by lyceum barbarum polysaccharides in protection against diabetic cataract.Oct 27, 2020

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Pubmed Data : J Ethnopharmacol. 2020 Oct 28 ;261:113165. Epub 2020 Jul 27. PMID: 32730875

Article Published Date : Oct 27, 2020

Study Type : In Vitro Study

Additional Links

Substances : Goji

Diseases : Diabetes: Cataract

Pharmacological Actions : Anti-Apoptotic

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Antibacterial effect and mechanism of anthocyanin from Lycium ruthenicum.Dec 31, 2021

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Pubmed Data : Front Microbiol. 2022 ;13:974602. Epub 2022 Aug 18. PMID: 36060738

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

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Substances : Anthocyanins, Goji

Diseases : Aspergillosis, Escherichia coli Infections, Staphylococcus aureus infection

Pharmacological Actions : Anti-Bacterial Agents

Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation

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Antioxidant effect of Lycium barbarum leaf through inflammatory and endoplasmic reticulum.Dec 27, 2020

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Exploration of the Effect and Mechanism of Fructus Lycii, Rehmanniae Radix Praeparata, and Paeonia lactiflora in the Treatment of AMD.Dec 31, 2020

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Pubmed Data : Exp Ther Med. 2016 Aug ;12(2):683-689. Epub 2016 Jun 2. PMID: 27446261

Article Published Date : Jul 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Goji

Diseases : Mercury Poisoning

Pharmacological Actions : Neurogenesis, Neuroprotective Agents

Additional Keywords : Hippocampus Regeneration, Neural Stem Cells

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Hepatoprotective effect of crude polysaccharide isolated from Lycium barbarum L. against alcohol-induced oxidative damage.Nov 30, 2020

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Pubmed Data : Food Sci Nutr. 2020 Dec ;8(12):6528-6538. Epub 2020 Oct 29. PMID: 33312537

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Synergistic antitumor effects of polysaccharides and anthocyanins from Lycium ruthenicum Murr. on human colorectal carcinoma LoVo cells and the molecular mechanism.Aug 31, 2022

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Pubmed Data : Biomed Res Int. 2016 ;2016:7529521. Epub 2016 Nov 14. PMID: 27965980

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Goji

Diseases : Liver Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Chemopreventive

Additional Keywords : Gene Expression Regulation

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View the Evidence: 152 Abstracts with Goji Research

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Cardiovascular disease risk reduction with wolfberry consumption.Nov 26, 2021

The effect of Lycium barbarum polysaccharide on the glucose and lipid metabolism.Jul 01, 2021

An extract of Lycium barbarum mimics exercise to improve muscle endurance through increasing type IIa oxidative muscle fibers by activating ERRγ.Aug 31, 2020

Delay of cone degeneration in retinitis pigmentosa using a 12-month treatment with Lycium barbarum supplement.Mar 11, 2019

Goji berry intake has antioxidative and anti-inflammatory effects in overweight and hypercholesterolemic subjects.Jan 17, 2017

Goji berry supplementation may be of therapeutic value in macular degeneration. Feb 01, 2011

Goji improves sense of well-being, and other indicators of good health.May 01, 2008

Lycium barbarum polysaccharide inhibited hypoxia-inducible factor 1 in COPD patients.Dec 31, 2019

Supplementation of Lycium barbarum polysaccharide combined with aerobic exercise ameliorates high-fat-induced nonalcoholic steatohepatitis.Aug 07, 2022

The daily consumption of goji berry juice significantly increases several immunological responses and subjective feelings of general well-being without any adverse reactions.Oct 01, 2009

Wolfberry consumption with a healthy dietary pattern lowers oxidative stress in middle-aged and older adults.Apr 06, 2021

Goji berry extracts have chemopreventive potential in breast cancer treatment.Nov 01, 2015

Lycium barbarum polysaccharides promotes mitochondrial biogenesis and energy balance in a NAFLD cell model.Dec 06, 2021

A wolfberry (goji) preparation prevents prenatal stress-induced cognitive impairment of offspring rats and inhibits oxidative damage and mitochondrial dysfunction. Feb 05, 2010

Administration of Lycium barbarum polysaccharides and capsaicin attenuate dextran sulfate sodium-induced ulcerative colitis symptoms.Feb 21, 2022

Ameliorative potentials of the ethanolic extract from Lycium chinense leaf extract against diabetic cardiomyopathy.Sep 30, 2022

An arabinogalactan from Lycium barbarum attenuates DSS-induced chronic colitis.Oct 18, 2021

Anxiolytic, antioxidant, and neuroprotective effects of goji berry polysaccharides in ovariectomized rats.Dec 31, 2019

Berry fruits presented antioxidant and anti-inflammatory activities in vitro and in vivo.Feb 29, 2016

Betaine, a component of Lycium chinense, enhances muscular endurance of mice and myogenesis of myoblasts.Aug 31, 2021

Combined Lycium babarum polysaccharides and C-phycocyanin increase gastric Bifidobacterium relative abundance and protect against gastric ulcer caused by aspirin.Jan 05, 2021

Dietary goji shapes the gut microbiota to prevent the liver injury induced by acute alcohol Intake.Dec 31, 2021

Dietary supplementation with goji berry enhances the immune response and reduces pathogenesis to influenza infection in mice.Jul 31, 2012

Dietary wolfberry upregulates carotenoid metabolic genes and enhances mitochondrial biogenesis in the retina of db/db diabetic mice.Mar 14, 2013

Effects of Lycium barbarum glycopeptide on renal and testicular injury induced by di(2-ethylhexyl) phthalate.Mar 31, 2022

Flavonoids from Lycium barbarum leaves attenuate obesity.Dec 31, 2021

Flavonoids from Lycium barbarum leaves exhibit anti-aging effects through the redox-modulation.Aug 02, 2022

Gastroprotective effect of Lycium barbarum polysaccharides and C-phycocyanin in rats with ethanol-induced gastric ulcer.Dec 14, 2020

Goji (lycopom barbarum) exhibits a neuroprotective effect against beta-amyloid peptide neurotoxicity.Aug 01, 2005

Goji berry seed oil exhibits anti-atherosclerotic activity comparable to lovastatin. Jun 01, 2007

Goji exhibits therapeutic activity in an experimental model of hypertension. Jun 01, 1998

Goji extracts may have a positive effect to improve erectile function in an old-aged rat model.Dec 21, 2016

Goji fruit protects sciatic nerve function against crush injury in a model of diabetic stress.Jun 30, 2016

Goji inhibits the growth of estrogen receptor positive human breast cancer by favoring altering estradiol metabolism. Jan 01, 2009

Goji polysaccharide attenuates diabetic testicular dysfunction.Aug 01, 2018

Goji polysaccharide can exert functional recovery of memory and motor coordination deficits in cerebral ischemic injured mice.May 14, 2017

Goji polysaccharide can protect against focal cerebral ischemic reperfusion injury in mice.Jun 30, 2015

Goji polysaccharide has attenuated oxidative stress and inflammation to show antidiabetic and antinephritic effects.Dec 31, 2015

Goji polysaccharide may be potentially useful for treating Huntington's disease.Jul 31, 2016

Goji polysaccharides have protective effects on diabetic nephropathy.Jul 14, 2016

Goji polysaccharides showed a protective effect on BMNC against ionizing radiation-induced apoptosis and oxidative damage.Dec 31, 2015

Goji signficantly enhances peripheral platelet and white blood cell counts in irradiation and chemotherapy-induced myelosuppressive mice. Apr 01, 2005

Hepatoprotection of Lycii fructus polysaccharide against oxidative stress.Dec 31, 2020

Hypoglycemic effects of Lycium barbarum polysaccharide in type 2 diabetes mellitus.Dec 31, 2021

Impact of Lycium barbarum arabinogalactan on the fecal metabolome in a DSS-induced chronic colitis model.Aug 14, 2022

Lycium barbarum (goji) and Rehmannia glutinosa inhibit liver cancer.Jul 01, 2007

Lycium barbarum Glycopeptide prevents the development and progression of acute colitis.Dec 31, 2021

Lycium barbarum L. leaves ameliorate type 2 diabetes.Dec 31, 2019

Lycium barbarum lipid-based edible nanoparticles protect against experimental colitis.Dec 22, 2019

Lycium barbarum mitigates radiation injury via regulation of the immune function, gut microbiota, and related metabolites.Jun 30, 2021

Lycium barbarum polysaccharide ameliorates Sjögren's syndrome.Dec 31, 2020

Lycium barbarum polysaccharide attenuates myocardial injury in high-fat diet-fed mice.Jan 11, 2020

Lycium barbarum polysaccharide attenuates Pseudomonas-aeruginosa pyocyanin-induced cellular injury.Dec 31, 2021

Lycium barbarum polysaccharide exhibits cardioprotection in an experimental model of ischemia-reperfusion damage.Apr 30, 2017

Lycium barbarum polysaccharide has potential for preventing male infertility caused by obesity.Dec 31, 2019

Lycium barbarum polysaccharide is an effective and safe hepatoprotective agent against alcoholic liver disease.Jun 30, 2018

Lycium barbarum polysaccharide may improve allergic asthma by altering gut microbiota and inhibiting inflammation in mice.May 10, 2020

Lycium barbarum polysaccharide modulates gut microbiota to alleviate rheumatoid arthritis in a rat model.Jul 20, 2022

Lycium barbarum polysaccharide protects against ethanol-induced spermiotoxicity and testicular degeneration in Immp2l+/- mice.Apr 30, 2020

Lycium barbarum polysaccharide protects rats and cardiomyocytes against ischemia/reperfusion injury.Oct 31, 2021

Lycium barbarum polysaccharide reduces hyperoxic acute lung injury in mice through Nrf2 pathway.Jan 02, 2019

Lycium barbarum polysaccharides and aerobic exercise might be a promising treatment for NAFLD.May 12, 2021

Lycium barbarum polysaccharides and Wolfberry juice prevent DEHP-induced hepatotoxicity.Feb 05, 2021

Lycium barbarum polysaccharides attenuate kidney injury in sepsis.Dec 27, 2019

Lycium barbarum polysaccharides attenuates the apoptosis of hippocampal neurons induced by sevoflurane.Aug 31, 2018

Lycium barbarum polysaccharides could be of use in healthy aging and reduce the incidence of age-related diseases.Dec 31, 2018

Lycium barbarum polysaccharides had anti-inflammatory effects in diabetic mice. Jan 24, 2018

Lycium barbarum polysaccharides Improve diabetic retinopathy.Dec 31, 2017

Lycium barbarum polysaccharides improve hepatic injury.Sep 24, 2018

Lycium barbarum polysaccharides improve testicular spermatogenic function in streptozotocin-induced diabetic rats.Dec 31, 2019

Lycium barbarum polysaccharides inhibit ischemia/reperfusion-induced myocardial injury.Dec 31, 2020

Lycium barbarum polysaccharides protect mice from hyperuricaemia.Nov 30, 2020

View the Evidence:
152 Abstracts with Goji Research