Goldenseal

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18 Diseases Researched for Goldenseal

Name	AC	CK
Acetaminophen (Tylenol) Toxicity	1	2
Bacterial Infections and Mycoses	2	2
Breast Cancer	2	2
Cervical Cancer	2	2
Liver Damage: Drug-Induced	1	2
Cholesterol: High	1	1
Escherichia coli Infections	1	1
Helicobacter Pylori Infection	1	1
High Cholesterol	1	1
Hypercholesterolemia	1	1
Malignant Melanoma	1	1
Melanoma	1	1
Oral Infection	1	1
Periodontal Diseases	1	1
Pseudomonas aeruginosa	1	1
Staphylococcus aureus infection	1	1
Staphylococcus aureus: Methicillin-resistant (MRSA)	1	1
Streptococcus Infections	1	1

10 Pharmacological Actions Researched for Goldenseal

Name	AC	CK
Anti-Bacterial Agents	4	4
Apoptotic	2	2
Hepatoprotective	1	2
Anti-Proliferative	1	1
Anticarcinogenic Agents	1	1
Antineoplastic Agents	1	1
Cell cycle arrest	1	1
Chemopreventive	1	1
Chemotherapeutic	1	1
Hypolipidemic	1	1

Research Articles 12
Cumulative Knowledge Score 19
Overall Research Rating GOOD

View the Evidence:
12 Abstracts with Goldenseal Research

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[+]

Goldenseal has hepatoprotective effects that ameliorate acetaminophen induced acute liver failure in rats.Sep 30, 2011

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pharmacognosy Res. 2011 Oct ;3(4):250-5. PMID: 22224048

Article Published Date : Sep 30, 2011

Study Type : Animal Study

Additional Links

Substances : Goldenseal

Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage: Drug-Induced

Pharmacological Actions : Hepatoprotective

Problem Substances : Acetaminophen, Paracetamol

[+]

An extract of the Goldenseal has demonstrable chemopreventive effects on HeLa cells in vitro.Jun 30, 2013

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Pubmed Data : Environ Toxicol Pharmacol. 2013 Jul ;36(1):202-14. Epub 2013 Apr 8. PMID: 23628949

Article Published Date : Jun 30, 2013

Study Type : In Vitro Study

Additional Links

Substances : Goldenseal

Diseases : Cervical Cancer

Pharmacological Actions : Apoptotic, Chemopreventive

Additional Keywords : Plant Extracts

[+]

Antimicrobial activity of goldenseal (Hydrastis canadensis) against methicillin-resistant Staphylococcus aureus (MRSA).Aug 31, 2012

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Pubmed Data : Planta Med. 2012 Sep ;78(14):1556-61. Epub 2012 Jul 18. PMID: 22814821

Article Published Date : Aug 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Goldenseal

Diseases : Staphylococcus aureus: Methicillin-resistant (MRSA)

Pharmacological Actions : Anti-Bacterial Agents

[+]

Barberry, Goldenseal, Oregan grape and Goldenthread contains berberine, a powerful antimicrobial.Apr 01, 2000

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Pubmed Data : 1: Altern Med Rev. 2000 Apr;5(2):175-7. PMID: 12203264

Article Published Date : Apr 01, 2000

Study Type : In Vitro Study

Additional Links

Substances : Barberry, Berberine, Goldenseal, Goldenthread, Oregon Grape

Diseases : Bacterial Infections and Mycoses

[+]

Berberine, a compound found within plants such as goldenseal, inhibit the growth of melanoma cell lines. May 01, 2008

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Pubmed Data : Cancer Chemother Pharmacol. 2008 May;61(6):1007-18. Epub 2007 Jul 28. PMID: 17661039

Article Published Date : May 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Berberine, Goldenseal

Diseases : Malignant Melanoma, Melanoma

Pharmacological Actions : Anti-Proliferative

[+]

Goldenseal (H. canadensis) demonstrates antibacterial activity against Staphloccocal, Steptococcal, E. coli and Pseudomonas aeruginosa strains in vitro. Aug 01, 2001

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Pubmed Data : Planta Med. 2001 Aug;67(6):561-4. PMID: 11509983

Article Published Date : Aug 01, 2001

Study Type : In Vitro Study

Additional Links

Substances : Goldenseal

Diseases : Bacterial Infections and Mycoses, Escherichia coli Infections, Pseudomonas aeruginosa, Staphylococcus aureus infection, Streptococcus Infections

Pharmacological Actions : Anti-Bacterial Agents

[+]

Goldenseal contains compounds which inhibit a variety of oral pathogens. Jul 01, 2003

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Pubmed Data : Planta Med. 2003 Jul;69(7):623-7. PMID: 12898417

Article Published Date : Jul 01, 2003

Study Type : In Vitro Study

Additional Links

Substances : Goldenseal

Diseases : Oral Infection , Periodontal Diseases

Pharmacological Actions : Anti-Bacterial Agents

[+]

Goldenseal is a natural LDL-lowering agent.Oct 01, 2006

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Pubmed Data : J Lipid Res. 2006 Oct;47(10):2134-47. Epub 2006 Aug 2. PMID: 16885565

Article Published Date : Oct 01, 2006

Study Type : Review

Additional Links

Substances : Goldenseal

Diseases : Cholesterol: High, High Cholesterol, Hypercholesterolemia

Pharmacological Actions : Hypolipidemic

Additional Keywords : LDL Reduction

[+]

Hydrastis canadensis and Marsdenia condurango triggered epigenetic modifications and alterations in gene expression profiles of many genes associated with carcinogenesis.Oct 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Integr Med. 2015 Nov ;13(6):400-11. PMID: 26559365

Article Published Date : Oct 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Goldenseal, Homeopathic Medicine: All

Diseases : Cervical Cancer

Pharmacological Actions : Anticarcinogenic Agents

Additional Keywords : Epigenetic Modification In Cancer, Low-Dose Pharmacology

[+]

Hydrastis may have a selective cytotoxic effect against hormone-dependent breast cancer MCF 7 cells.Oct 31, 2020

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Pubmed Data : Homeopathy. 2020 Nov ;109(4):198-206. Epub 2020 Jul 1. PMID: 32610349

Article Published Date : Oct 31, 2020

Study Type : In Vitro Study

Additional Links

Substances : Goldenseal, Homeopathic Medicine: All

Diseases : Breast Cancer

Pharmacological Actions : Antineoplastic Agents, Apoptotic, Cell cycle arrest

Additional Keywords : Plant Extracts

[+]

In silico analysis of the effect of Hydrastis canadensis on controlling breast cancer.Aug 01, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Medicina (Kaunas). 2023 Aug 2 ;59(8). Epub 2023 Aug 2. PMID: 37629702

Article Published Date : Aug 01, 2023

Study Type : In Vitro Study

Additional Links

Substances : Goldenseal

Diseases : Breast Cancer

Pharmacological Actions : Chemotherapeutic

[+]

S. canadensis (bloodroot) and H. canadensis (goldenseal) inhibit Helicobacter pylori growth. Dec 01, 2007

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Pubmed Data : J Med Food. 2007 Dec;10(4):694-701. PMID: 12672149

Article Published Date : Dec 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Bloodroot, Goldenseal

Diseases : Helicobacter Pylori Infection

Pharmacological Actions : Anti-Bacterial Agents

Research Articles 12
Cumulative Knowledge Score 19
Overall Research Rating GOOD

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Berberine for Chemoprevention of Colon Polyps: A Randomized Placebo-Controlled Trial

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Beyond Metformin: Berberine's Promise in the Fight Against Type 2 Diabetes

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In a world where type 2 diabetes is reaching epidemic proportions, a golden-hued herb is emerging as a potential game-changer, rivaling one of medicine's most prescribed drugs.

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 12 Abstracts with Goldenseal Research

Limited to Members Only

Currently Available Sorting Options

Goldenseal has hepatoprotective effects that ameliorate acetaminophen induced acute liver failure in rats.Sep 30, 2011

An extract of the Goldenseal has demonstrable chemopreventive effects on HeLa cells in vitro.Jun 30, 2013

Antimicrobial activity of goldenseal (Hydrastis canadensis) against methicillin-resistant Staphylococcus aureus (MRSA).Aug 31, 2012

Barberry, Goldenseal, Oregan grape and Goldenthread contains berberine, a powerful antimicrobial.Apr 01, 2000

Berberine, a compound found within plants such as goldenseal, inhibit the growth of melanoma cell lines. May 01, 2008

Goldenseal (H. canadensis) demonstrates antibacterial activity against Staphloccocal, Steptococcal, E. coli and Pseudomonas aeruginosa strains in vitro. Aug 01, 2001

Goldenseal contains compounds which inhibit a variety of oral pathogens. Jul 01, 2003

Goldenseal is a natural LDL-lowering agent.Oct 01, 2006

Hydrastis canadensis and Marsdenia condurango triggered epigenetic modifications and alterations in gene expression profiles of many genes associated with carcinogenesis.Oct 31, 2015

Hydrastis may have a selective cytotoxic effect against hormone-dependent breast cancer MCF 7 cells.Oct 31, 2020

In silico analysis of the effect of Hydrastis canadensis on controlling breast cancer.Aug 01, 2023

S. canadensis (bloodroot) and H. canadensis (goldenseal) inhibit Helicobacter pylori growth. Dec 01, 2007

Goldenseal Related Articles

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Goldenseal

View the Evidence:
12 Abstracts with Goldenseal Research