Griffithsin

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1 Diseases Researched for Griffithsin
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Coronavirus Infection11Locked
1 Pharmacological Actions Researched for Griffithsin
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Antiviral Agents11Locked

View the Evidence:
30 Abstracts with Griffithsin Research

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Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antimicrob Agents Chemother. 2014 ;58(1):120-7. Epub 2013 Oct 21. PMID: 24145548
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Griffithsin
Diseases : Coronavirus Infection, Hepatitis C, HIV Infections
Pharmacological Actions : Anti-HIV Agents, Antiviral Agents
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Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo.Jan 23, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nat Commun. 2018 09 24 ;9(1):3881. Epub 2018 Sep 24. PMID: 30250170
Article Published Date : Jan 23, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : Herpes Simplex Virus Type 2, HIV Infections, Human Papillomavirus (HPV)
Pharmacological Actions : Antiviral Agents
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Griffithsin has antiviral activity against hepatitis C virus. Oct 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antimicrob Agents Chemother. 2011 Nov ;55(11):5159-67. Epub 2011 Sep 6. PMID: 21896910
Article Published Date : Oct 31, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : Hepatitis C
Pharmacological Actions : Antiviral Agents
Additional Keywords : Lectins
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Griffithsin inhibits Japanese encephalitis virus infection in vitro and in vivoJan 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Virol. 2013 Feb ;158(2):349-58. Epub 2012 Oct 7. PMID: 23053519
Article Published Date : Jan 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : Encephalitis: Japanese
Pharmacological Actions : Antiviral Agents
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Griffithsin inhibits nipah virus entry and fusion and can protect Syrian golden hamsters from lethal nipah virus challenge.May 10, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Infect Dis. 2020 May 11 ;221(Supplement_4):S480-S492. PMID: 32037447
Article Published Date : May 10, 2020
Study Type : Animal Study
Additional Links
Substances : Griffithsin
Diseases : Nipah Virus Encephalitis
Pharmacological Actions : Antiviral Agents
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Pharmacokinetics of the antiviral lectin griffithsin administered by different routes indicates multiple potential uses.Jan 16, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Viruses. 2016 12 17 ;8(12). Epub 2016 Dec 17. PMID: 27999325
Article Published Date : Jan 16, 2016
Study Type : Animal Study
Additional Links
Substances : Griffithsin
Diseases : Coronavirus Infection, Encephalitis: Japanese, Hepatitis C, Herpes Simplex Virus Type 2
Pharmacological Actions : Antiviral Agents
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Efficacy of silk fibroin biomaterial vehicle for in vivo mucosal delivery of Griffithsin and protection against HIV and SHIV infection ex vivo.Sep 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Int AIDS Soc. 2020 Oct ;23(10):e25628. PMID: 33073530
Article Published Date : Sep 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : HIV Infections
Pharmacological Actions : Antiviral Agents
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A comprehensive review of the antiviral potential of algal metabolites.Feb 05, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2021 Feb 6 ;19(2). Epub 2021 Feb 6. PMID: 33562153
Article Published Date : Feb 05, 2021
Study Type : Review
Additional Links
Substances : Griffithsin, Seaweed
Diseases : Dengue, Ebola, Hepatitis C, HIV Infections
Pharmacological Actions : Antiviral Agents
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Combinations of griffithsin with other carbohydrate-binding agents demonstrate superior activity against HIV type 1, HIV type 2.Oct 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : AIDS Res Hum Retroviruses. 2012 Nov ;28(11):1513-23. Epub 2012 Jun 25. PMID: 22607556
Article Published Date : Oct 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : HIV Infections
Pharmacological Actions : Anti-HIV Agents
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Griffithsin and carrageenan combination to target herpes simplex virus 2 and human papillomavirus.Nov 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antimicrob Agents Chemother. 2015 Dec ;59(12):7290-8. Epub 2015 Sep 14. PMID: 26369967
Article Published Date : Nov 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Carrageenans, Griffithsin
Diseases : Herpes Simplex Virus Type 2, Human Papillomavirus (HPV)
Pharmacological Actions : Antiviral Agents
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Griffithsin could be used as a microbicide for HIV prevention.Jan 16, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Viruses. 2016 11 17 ;8(11). Epub 2016 Nov 17. PMID: 27869695
Article Published Date : Jan 16, 2016
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : HIV Infections
Pharmacological Actions : Antiviral Agents
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Griffithsin retains anti-HIV-1 potency with changes in gp120 glycosylation and complements broadly neutralizing antibodies PGT121 and PGT126.Jan 19, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antimicrob Agents Chemother. 2019 12 20 ;64(1). Epub 2019 Dec 20. PMID: 31611356
Article Published Date : Jan 19, 2019
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : HIV Infections
Pharmacological Actions : Antiviral Agents
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Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virusJan 22, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Retrovirology. 2015 Jan 23 ;12:6. Epub 2015 Jan 23. PMID: 25613831
Article Published Date : Jan 22, 2015
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : HIV Infections
Pharmacological Actions : Antiviral Agents
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Griffithsin, a highly potent broad-spectrum antiviral lectin from red algae: from discovery to clinical application.Oct 05, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2019 Oct 6 ;17(10). Epub 2019 Oct 6. PMID: 31590428
Article Published Date : Oct 05, 2019
Study Type : Review
Additional Links
Substances : Griffithsin
Diseases : HIV Infections
Pharmacological Actions : Antiviral Agents
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Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti-HIV microbicide.Jul 31, 2007

Pubmed Data : J Med Primatol. 2007 Aug ;36(4-5):244-53. PMID: 17669213
Article Published Date : Jul 31, 2007
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : HIV Infections
Pharmacological Actions : Anti-HIV Agents
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Griffithsin: an antiviral lectin with outstanding therapeutic potential. Jan 23, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Viruses. 2016 10 24 ;8(10). Epub 2016 Oct 24. PMID: 27783038
Article Published Date : Jan 23, 2016
Study Type : Review
Additional Links
Substances : Griffithsin
Diseases : Coronavirus Infection, Ebola, HIV Infections, Influenza, Zika Virus
Pharmacological Actions : Antiviral Agents
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Hantavirus infection Is inhibited by griffithsin in cell culture. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Infect Microbiol. 2020 ;10:561502. Epub 2020 Nov 4. PMID: 33251157
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : Hantavirus Infections
Pharmacological Actions : Antiviral Agents
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High-level expression of the HIV entry inhibitor griffithsin from the plastid genome and retention of biological activity in dried tobacco leaves.Jun 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Plant Mol Biol. 2018 Jul ;97(4-5):357-370. Epub 2018 Jun 9. PMID: 29948657
Article Published Date : Jun 30, 2018
Study Type : In Vitro Study, Plant Study
Additional Links
Substances : Griffithsin
Diseases : HIV Infections
Pharmacological Actions : Anti-HIV Agents, Antiviral Agents
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In vitro antiviral activity of griffithsin against porcine epidemic diarrhea virus.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Virus Genes. 2019 Apr ;55(2):174-181. Epub 2019 Jan 14. PMID: 30637608
Article Published Date : Mar 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : Animal Diseases: Porcine Epidemic Diarrhea Virus (PEDV)
Pharmacological Actions : Antiviral Agents
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In vitro study on synergistic interactions between free and encapsulated Q-griffithsin and antiretrovirals against HIV-1 infection.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Nanomedicine. 2021 ;16:1189-1206. Epub 2021 Feb 15. PMID: 33623382
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : HIV Infections
Pharmacological Actions : Anti-HIV Agents, Apoptotic
Additional Keywords : Natural Substance/Drug Synergy
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Middle East respiratory syndrome coronavirus infection is inhibited by griffithsin.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antiviral Res. 2016 09 ;133:1-8. Epub 2016 Jul 15. PMID: 27424494
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : Coronavirus Infection
Pharmacological Actions : Antiviral Agents
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Natural product-derived phytochemicals as potential agents against coronaviruses: a reviewJul 14, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Virus Res. 2020 Jul 15 ;284:197989. Epub 2020 Apr 30. PMID: 32360300
Article Published Date : Jul 14, 2020
Study Type : Review
Additional Links
Substances : Caffeic Acid, Griffithsin, Myricetin, Quercetin
Diseases : Coronavirus Infection
Pharmacological Actions : Antiviral Agents
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Potent strategy to inhibit HIV-1 by binding both gp120 and gp41.Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antimicrob Agents Chemother. 2011 Jan ;55(1):264-75. Epub 2010 Oct 18. PMID: 20956603
Article Published Date : Dec 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : HIV Infections
Pharmacological Actions : Antiviral Agents
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Preformulation characterization of griffithsin, a biopharmaceutical candidate for HIV prevention.Feb 23, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : AAPS PharmSciTech. 2021 Feb 24 ;22(3):83. Epub 2021 Feb 24. PMID: 33625602
Article Published Date : Feb 23, 2021
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : HIV Infections
Pharmacological Actions : Anti-HIV Agents
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Rapid-release griffithsin fibers for dual prevention of HSV-2 and HIV-1 infections. May 20, 2020

Pubmed Data : Antimicrob Agents Chemother. 2020 May 21 ;64(6). Epub 2020 May 21. PMID: 32229493
Article Published Date : May 20, 2020
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : Herpes Simplex Virus Type 2, HIV Infections
Pharmacological Actions : Antiviral Agents
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Sustained-release griffithsin nanoparticle-fiber composites against HIV-1 and HSV-2 infections.May 09, 2020

Pubmed Data : J Control Release. 2020 May 10 ;321:84-99. Epub 2020 Feb 5. PMID: 32035194
Article Published Date : May 09, 2020
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : Herpes Simplex Virus Type 2, HIV Infections
Pharmacological Actions : Antiviral Agents
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Synergistic activity profile of griffithsin in combination with tenofovir, maraviroc and enfuvirtide against HIV-1 clade C.Aug 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Virology. 2011 Sep 1 ;417(2):253-8. Epub 2011 Jul 28. PMID: 21802104
Article Published Date : Aug 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : HIV Infections
Pharmacological Actions : Anti-HIV Agents, Antiviral Agents
Additional Keywords : Natural Substance/Drug Synergy
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The lectins Griffithsin, Cyanovirin-N and Scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4+ cellsFeb 19, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Virology. 2012 Feb 20 ;423(2):175-86. Epub 2011 Dec 29. PMID: 22209231
Article Published Date : Feb 19, 2012
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : HIV Infections
Pharmacological Actions : Antiviral Agents
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The remarkable potency profile of Griffithsin supports its potential value as an antiviral agent against porcine reproductive and respiratory syndrome virus.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Virol. 2018 Dec ;163(12):3317-3325. Epub 2018 Sep 15. PMID: 30220033
Article Published Date : Nov 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : Respiratory Infections
Pharmacological Actions : Antiviral Agents
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These findings demonstrate that griffithsin inhibits HSV-2 by a unique mechanism of blocking cell-to-cell spread.May 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Virol. 2013 Jun ;87(11):6257-69. Epub 2013 Mar 27. PMID: 23536670
Article Published Date : May 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : Herpes Simplex Virus Type 2, HIV Infections
Pharmacological Actions : Antiviral Agents

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