Guarana

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13 Diseases Researched for Guarana
NameACCKFocus
Cachexia: Cancer110Locked
Oxidative Stress110Locked
Liver Cancer23Locked
Breast Cancer22Locked
Cognitive Decline/Dysfunction12Locked
Colorectal Cancer22Locked
Hypercholesterolemia12Locked
Hyperlipidemia12Locked
Lung Cancer12Locked
Mercury Poisoning12Locked
Acute T cell Leukemias11Locked
Non-Hodgkin Lymphoma11Locked
Promyelocytic leukemia 11Locked
15 Pharmacological Actions Researched for Guarana
NameACCKFocus
Antioxidants212Locked
Appetite Stimulants110Locked
Catalase Up-Regulation110Locked
Hypolipidemic24Locked
Anticholesteremic Agents12Locked
Antiproliferative 22Locked
Detoxifier12Locked
Hepatoprotective12Locked
Neuroprotective Agents12Locked
Anti-Bacterial Agents11Locked
Antineoplastic Agents11Locked
Apoptotic11Locked
Chemosensitizer11Locked
Immunomodulatory11Locked
Tumor Suppressor Protein p53 Upregulation11Locked

View the Evidence:
26 Abstracts with Guarana Research

[+]

Effect of guarana on cognitive performance.Jan 13, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Jan 14 ;15(2). Epub 2023 Jan 14. PMID: 36678305
Article Published Date : Jan 13, 2023
Study Type : Meta Analysis, Review
Additional Links
Substances : Guarana
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Guarana catechins are bioavailable and contribute to reduce the oxidative stress of clinically healthy individuals.Jul 12, 2016

Pubmed Data : Food Funct. 2016 Jul 13 ;7(7):2970-8. PMID: 27302304
Article Published Date : Jul 12, 2016
Study Type : Human Study
Additional Links
Substances : Guarana
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Catalase Up-Regulation
[+]

Guarana led to weight stabilization and increased appetites in patients with cachexia. Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Diet Suppl. 2016 ;13(2):221-31. Epub 2015 Feb 19. PMID: 25695932
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Guarana
Diseases : Cachexia: Cancer
Pharmacological Actions : Appetite Stimulants
[+]

These results indicate that guarana seed powder have potential applications for blood cholesterol management.Nov 30, 2022

Pubmed Data : Food Res Int. 2022 Dec ;162(Pt A):111968. Epub 2022 Sep 26. PMID: 36461218
Article Published Date : Nov 30, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Guarana
Diseases : Hypercholesterolemia
Pharmacological Actions : Anticholesteremic Agents
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Guarana (Paullinia cupana) consumption improves hepatic and renal parameters in alloxan-induced diabetic rats.Nov 19, 2019

Pubmed Data : Nutr Hosp. 2019 Nov 20. Epub 2019 Nov 20. PMID: 31746621
Article Published Date : Nov 19, 2019
Study Type : Animal Study
Additional Links
Substances : Guarana
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Hepatoprotective, Renoprotective
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Guarana has an anti-proliferative, pro-apoptic effect on lung melanoma lung metastases in mice.Apr 01, 2008

Pubmed Data : Braz J Med Biol Res. 2008 Apr;41(4):305-10. PMID: 18392453
Article Published Date : Apr 01, 2008
Study Type : Animal Study
Additional Links
Substances : Guarana
Diseases : Lung Cancer
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Guarana hydroalcoholic extract has therapeutic potential in combating age-related diseases associated with protein misfolding and accumulation.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:9241308. Epub 2018 Jul 4. PMID: 30116496
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Guarana
Diseases : Alzheimer's Disease, Huntington Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Guarana improves behavior and inflammatory alterations triggered by methylmercury exposure.Apr 30, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 May ;26(15):15069-15083. Epub 2019 Mar 27. PMID: 30915696
Article Published Date : Apr 30, 2019
Study Type : In Vitro Study, Insect Study
Additional Links
Substances : Guarana
Diseases : Mercury Poisoning
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Methylmercury
Problem Substances : Mercury
[+]

Guarana leads to an increase in energetic metabolism and stimulates mitochondrial biogenesis.Jan 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Jan 31 ;10(2). Epub 2018 Jan 31. PMID: 29385074
Article Published Date : Jan 30, 2018
Study Type : Animal Study
Additional Links
Substances : Guarana
Diseases : High Fat Diet, Obesity
Additional Keywords : Anti-Obesity Agents
[+]

Guarana powder may be an adjuvant therapy in the management of hyperlipidemia and cognitive disorders.Dec 31, 2016

Pubmed Data : Physiol Behav. 2017 Jan 1 ;168:11-19. Epub 2016 Oct 6. PMID: 27720901
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Guarana
Diseases : Cognitive Decline/Dysfunction, Hyperlipidemia
Pharmacological Actions : Hepatoprotective, Hypolipidemic, Neuroprotective Agents
Additional Keywords : Natural Substances Versus Drugs
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Guarana reduces the severity of chemically induced liver cancer in a mouse experimental model. Feb 20, 2006

Pubmed Data : Cancer Lett. 2006 Feb 20;233(1):158-64. PMID: 15885883
Article Published Date : Feb 20, 2006
Study Type : Animal Study
Additional Links
Substances : Guarana
Diseases : Liver Cancer
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Guarana supplementation attenuated obesity, insulin resistance, and adipokines dysregulation induced by a standardized human Western diet.Apr 30, 2019

Pubmed Data : Phytother Res. 2019 May ;33(5):1394-1403. Epub 2019 Mar 13. PMID: 30868680
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Guarana
Diseases : Insulin Resistance, Obesity
Additional Keywords : Anti-Obesity Agents
Anti Therapeutic Actions : Western Diet
[+]

Guaraná was able to reduce the total cholesterol and low-density lipoprotein cholesterol to basal levels in hypercholesterolemic rats.Dec 31, 2015

Pubmed Data : Phytother Res. 2016 Jan ;30(1):49-57. Epub 2015 Oct 30. PMID: 26514663
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Guarana
Diseases : Hypercholesterolemia
Pharmacological Actions : Anticholesteremic Agents, Hypolipidemic
[+]

Mechanisms involved in anti-aging effects of guarana in Caenorhabditis elegans.Jul 01, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Braz J Med Biol Res. 2018 Jul 2 ;51(9):e7552. Epub 2018 Jul 2. PMID: 29972429
Article Published Date : Jul 01, 2018
Study Type : Animal Study
Additional Links
Substances : Guarana
Diseases : Aging
Pharmacological Actions : Antioxidants
Additional Keywords : Gene Expression Regulation, Plant Extracts
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Paullinia cupana seed extract ameliorated methotrexate-induced testicular dysfunction.Sep 26, 2022

Pubmed Data : Environ Sci Pollut Res Int. 2022 Sep 27. Epub 2022 Sep 27. PMID: 36168017
Article Published Date : Sep 26, 2022
Study Type : Animal Study
Additional Links
Substances : Guarana
Diseases : Drug Toxicity: Methotrexate, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Protective effects of guarana against methotrexate-induced intestinal damage.Jun 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2021 Jul ;9(7):3397-3404. Epub 2021 May 19. PMID: 34262701
Article Published Date : Jun 30, 2021
Study Type : Animal Study
Additional Links
Substances : Guarana
Diseases : Drug-Induced Toxicity: Methotrexate
Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective
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Routine consumption of guarana might be beneficial in protecting against mercury-induced toxicity.Oct 31, 2016

Pubmed Data : Toxicol Res (Camb). 2016 Nov 1 ;5(6):1629-1638. Epub 2016 Aug 24. PMID: 28316775
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Guarana
Diseases : Mercury Poisoning
Pharmacological Actions : Antioxidants, Detoxifier
Additional Keywords : Gene Expression Regulation, Methylmercury
Problem Substances : Mercury
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The effect of Guarana on metabolic and inflammatory parameters in adult male mice programmed by maternal obesity.Apr 05, 2018

Pubmed Data : Eur J Nutr. 2018 Apr 6. Epub 2018 Apr 6. PMID: 29626231
Article Published Date : Apr 05, 2018
Study Type : Animal Study
Additional Links
Substances : Guarana
Diseases : Obesity
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Transgenerational Epigenetic Modification
[+]

Guaraná presented cell antiproliferative effect and increased anti-proliferative oxaliplatin sensitivity. Dec 16, 2015

Pubmed Data : Anticancer Agents Med Chem. 2015 Dec 17. Epub 2015 Dec 17. PMID: 26673759
Article Published Date : Dec 16, 2015
Study Type : In Vitro Study
Additional Links
Substances : Guarana
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer, Tumor Suppressor Protein p53 Upregulation
[+]

Guaraná presents in vitro antitumor activity in colorectal and breast cancer cell lines.May 31, 2017

Pubmed Data : Nutr Cancer. 2017 Jun 1:1-11. Epub 2017 Jun 1. PMID: 28569556
Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Guarana
Diseases : Breast Cancer, Colorectal Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Selective Cytotoxicity
[+]

Guarana seeds have antibacterial, antineoplastic, and immunomodulatory activity.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:1203274. Epub 2016 Dec 7. PMID: 28053639
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Guarana
Diseases : Acute T cell Leukemias, Breast Cancer, Liver Cancer, Non-Hodgkin Lymphoma, Promyelocytic leukemia
Pharmacological Actions : Anti-Bacterial Agents, Antineoplastic Agents, Immunomodulatory
Additional Keywords : Plant Extracts
[+]

Neuroprotective effects of guarana against vincristine in vitro exposure.Dec 31, 2017

Pubmed Data : J Prev Alzheimers Dis. 2018 ;5(1):65-70. PMID: 29405235
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Guarana
Diseases : Chemotherapy-Induced Toxicity: Vincristine
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
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Protective effect of guarana-loaded liposomes on hemolytic activity.Nov 10, 2019

Pubmed Data : Colloids Surf B Biointerfaces. 2019 Nov 11:110636. Epub 2019 Nov 11. PMID: 31757446
Article Published Date : Nov 10, 2019
Study Type : In Vitro Study
Additional Links
Substances : Guarana
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
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The results demonstrate the potential of P. cupana to control and prevent H. pylori infection.Jan 01, 2019

Pubmed Data : Nat Prod Res. 2019 Jan 2:1-4. Epub 2019 Jan 2. PMID: 30600691
Article Published Date : Jan 01, 2019
Study Type : In Vitro Study
Additional Links
Substances : Guarana
Diseases : Helicobacter Pylori Infection
Pharmacological Actions : Anti-Bacterial Agents
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The results indicated that six flavonoids from Psidium guajava exhibited significant antioxidant effects.Jan 31, 2018

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2018 Feb ;43(4):760-765. PMID: 29600652
Article Published Date : Jan 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Guarana
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Guarana has gastroprotective properties.Dec 01, 2003

Pubmed Data : Phytother Res. 2003 Dec;17(10):1199-202. PMID: 14669256
Article Published Date : Dec 01, 2003
Additional Links
Substances : Guarana

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