Guggul

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15 Diseases Researched for Guggul

Name	AC	CK
Acne	1	10
Arteriosclerosis	1	10
Cholesterol: Oxidation	1	10
High Cholesterol	1	10
Hypothyroidism	2	4
Prostate Cancer	2	2
Breast Cancer: Bone Metastasis	1	1
Cancers: All	1	1
Cancers: Multi-Drug Resistant	1	1
Cardiovascular Diseases	1	1
Inflammation	1	1
Lipopolysaccharide-Induced Toxicity	1	1
Multiple Myeloma	1	1
Otitis media	1	1
Triglycerides: Elevated	1	1

15 Pharmacological Actions Researched for Guggul

Name	AC	CK
Apoptotic	2	2
Cyclooxygenase 2 Inhibitors	2	2
Anti-Angiogenic	1	1
Anti-Inflammatory Agents	1	1
Anti-Tumor	1	1
Anti-metastatic	1	1
Bcl-2 protein down-regulation	1	1
Chemopreventive	1	1
Cyclooxygenase Inhibitors	1	1
Hypolipidemic	1	1
Matrix metalloproteinase-9 (MMP-9) inhibitor	1	1
NF-kappaB Inhibitor	1	1
Survivin Down-Regulation	1	1
Tumor Necrosis Factor (TNF) Alpha Inhibitor	1	1
Vascular Endothelial Growth Factor Inhibitors	1	1

Research Articles 13
Cumulative Knowledge Score 21
Overall Research Rating GOOD

View the Evidence:
13 Abstracts with Guggul Research

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Guggul extract is as at least as effective as tetracycline in treating nodulocystic acne. Oct 01, 1994

Click here to read the entire abstract

Pubmed Data : J Dermatol. 1994 Oct;21(10):729-31. PMID: 7798429

Article Published Date : Oct 01, 1994

Study Type : Human Study

Additional Links

Substances : Guggul

Diseases : Acne

Additional Keywords : Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs

[+]

Guggul may be beneficial against atherogenesis via lipid lowering and inhibition of LDL oxidation.Feb 01, 2004

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Pubmed Data : Atherosclerosis. 2004 Feb;172(2):239-46. PMID: 15019533

Article Published Date : Feb 01, 2004

Study Type : Human Study

Additional Links

Substances : Guggul

Diseases : Arteriosclerosis, Cholesterol: Oxidation, High Cholesterol

[+]

Guggul ameliorates hypothyroidism in the mouse experimental model.Jul 01, 2005

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Pubmed Data : J Athl Train. 2005 Jul-Sep;40(3):174-80. PMID: 15798994

Article Published Date : Jul 01, 2005

Study Type : Animal Study

Additional Links

Substances : Guggul

Diseases : Hypothyroidism

[+]

Guggul increases T3 concentrations and the T3/T4 ratio in mice. Jan 01, 1999

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Pubmed Data : Life Sci. 1999;65(12):PL137-41. PMID: 10503949

Article Published Date : Jan 01, 1999

Study Type : Animal Study

Additional Links

Substances : Guggul

Diseases : Hypothyroidism

[+]

A review of medicinal plants in treatment of hypertriglyceridemia.Sep 04, 2018

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2018 Sep 5 ;53:43-52. Epub 2018 Sep 5. PMID: 30668411

Article Published Date : Sep 04, 2018

Study Type : Review

Additional Links

Substances : Dill, Garlic, Guggul, Nigella sativa (aka Black Seed), Turmeric

Diseases : Triglycerides: Elevated

Pharmacological Actions : Hypolipidemic

[+]

Guggul has numerous benefits for cardiovascular health.Jan 01, 2008

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Pubmed Data : Mol Cancer Ther. 2008 Jan;7(1):171-80. PMID: 18078436

Article Published Date : Jan 01, 2008

Study Type : Review

Additional Links

Substances : Guggul

Diseases : Cardiovascular Diseases

[+]

Guggul inhibits both non-drug and drug-resistant cancer cells.Jun 30, 2007

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Pubmed Data : Biochem Pharmacol. 2007 Jun 30;74(1):118-30. Epub 2007 Mar 30. PMID: 17475222

Article Published Date : Jun 30, 2007

Study Type : In Vitro Study

Additional Links

Substances : Guggul

Diseases : Cancers: Multi-Drug Resistant

Additional Keywords : Drug Resistant Cancer

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Guggul inhibits inflammation by inhibiting lipid peroxidation and the Cox-1 and Cox-2 enzymes.Nov 01, 2004

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Pubmed Data : Chem Biodivers. 2004 Nov;1(11):1842-53. PMID: 17191820

Article Published Date : Nov 01, 2004

Study Type : In Vitro Study

Additional Links

Substances : Guggul

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase Inhibitors

[+]

Guggul may have therapeutic value in the treatment of otitis media.Dec 01, 2010

Click here to read the entire abstract

Pubmed Data : Int J Pediatr Otorhinolaryngol. 2010 Dec;74(12):1384-7. Epub 2010 Oct 23. PMID: 20971513

Article Published Date : Dec 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Guggul

Diseases : Lipopolysaccharide-Induced Toxicity, Otitis media

Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Guggul may inhibit the progression of cancers such as multiple myeloma and breast cancer by modulating inflammation and tumor cell-induced osteoclastogenesis. Jun 01, 2007

Click here to read the entire abstract

Pubmed Data : J Nerv Ment Dis. 2007 Jun;195(6):504-13. PMID: 16428513

Article Published Date : Jun 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Guggul

Diseases : Breast Cancer: Bone Metastasis, Multiple Myeloma

Pharmacological Actions : Anti-Tumor, NF-kappaB Inhibitor

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Guggulsterone induces programmed cell death in human prostate cancer cells.Aug 01, 2007

Click here to read the entire abstract

Pubmed Data : Cancer Res. 2007 Aug 1;67(15):7439-49. PMID: 17671214

Article Published Date : Aug 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Guggul

Diseases : Prostate Cancer

Pharmacological Actions : Apoptotic

[+]

Guggulsterone inhibits angiogenesis in human prostate cancer cells.Jan 01, 2008

Click here to read the entire abstract

Pubmed Data : Mol Cancer Ther. 2008 Jan;7(1):171-80. PMID: 18202020

Article Published Date : Jan 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Guggul

Diseases : Prostate Cancer

Pharmacological Actions : Anti-Angiogenic

[+]

This review describes the anti-cancer properties, molecular targets, and the apoptotic effects of guggulsterone.Nov 11, 2015

Click here to read the entire abstract

Pubmed Data : Curr Pharm Des. 2015 Nov 12. Epub 2015 Nov 12. PMID: 26561056

Article Published Date : Nov 11, 2015

Study Type : Review

Additional Links

Substances : Guggul

Diseases : Cancers: All

Pharmacological Actions : Anti-metastatic, Apoptotic, Bcl-2 protein down-regulation, Chemopreventive, Cyclooxygenase 2 Inhibitors, Matrix metalloproteinase-9 (MMP-9) inhibitor, Survivin Down-Regulation, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Gene Expression Regulation

Research Articles 13
Cumulative Knowledge Score 21
Overall Research Rating GOOD

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While pharmaceutical companies race to meet demand for costly weight-loss injections, new research suggests that a centuries-old natural remedy--hops extract--may offer a safer, effective, and affordable alternative for appetite control.

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 13 Abstracts with Guggul Research

Limited to Members Only

Currently Available Sorting Options

Guggul extract is as at least as effective as tetracycline in treating nodulocystic acne. Oct 01, 1994

Guggul may be beneficial against atherogenesis via lipid lowering and inhibition of LDL oxidation.Feb 01, 2004

Guggul ameliorates hypothyroidism in the mouse experimental model.Jul 01, 2005

Guggul increases T3 concentrations and the T3/T4 ratio in mice. Jan 01, 1999

A review of medicinal plants in treatment of hypertriglyceridemia.Sep 04, 2018

Guggul has numerous benefits for cardiovascular health.Jan 01, 2008

Guggul inhibits both non-drug and drug-resistant cancer cells.Jun 30, 2007

Guggul inhibits inflammation by inhibiting lipid peroxidation and the Cox-1 and Cox-2 enzymes.Nov 01, 2004

Guggul may have therapeutic value in the treatment of otitis media.Dec 01, 2010

Guggul may inhibit the progression of cancers such as multiple myeloma and breast cancer by modulating inflammation and tumor cell-induced osteoclastogenesis. Jun 01, 2007

Guggulsterone induces programmed cell death in human prostate cancer cells.Aug 01, 2007

Guggulsterone inhibits angiogenesis in human prostate cancer cells.Jan 01, 2008

This review describes the anti-cancer properties, molecular targets, and the apoptotic effects of guggulsterone.Nov 11, 2015

Guggul Related Articles

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Guggul

View the Evidence:
13 Abstracts with Guggul Research