Holy Basil

Name	AC	CK
Dental Caries	4	22
Steptococcus Mutans Infections	3	21
Dental Plaque	2	20
Gingivitis	2	20
Coronavirus Infection	7	16
Cognitive Decline/Dysfunction	3	14
Periodontal Diseases	4	13
Anxiety Disorders	2	12
Obesity	2	12
Alzheimer's Disease	5	11
Radiation Induced Illness	6	11
Halitosis	1	10
Leukoplakia	1	10
Oral Cancer: Prevention	1	10
Oral Submucous Fibrosis	1	10
Dementia	3	9
Neurodegenerative Diseases	4	9
Oxidative Stress	6	9
Inflammation	5	7
Parkinson's Disease	2	6
Stress	3	6
Diabetes Mellitus: Type 2	3	4
Hyperglycemia	2	4
Leishmaniasis	2	4
Staphylococcus aureus infection	3	4
Chemotherapy and Radiation Toxicity	2	3
Diabetes: Cognitive Dysfunction	2	3
Klebsiella Infections	2	3
Lung Cancer	3	3
Neuropathic Pain	2	3
Streptococcus Infections	3	3
Alcohol Withdrawal	1	2
Amnesia	1	2
Amnesia: Drug-Induced	1	2
Anxiety	1	2
Arsenic Poisoning	1	2
Brain Inflammation	1	2
Cancers: All	2	2
Candida Albicans	2	2
Chemically-Induced Liver Damage	1	2
Cortisol: High	1	2
DNA damage	2	2
Dandruff	1	2
Diabetes Mellitus: Type 1	1	2
Diabetic Complications	1	2
Duodenal Ulcer	1	2
Escherichia coli Infections	2	2
Fever	1	2
Fluoride Toxicity	1	2
Fructose-Induced Toxicity	1	2
Gastric Ulcer	1	2
Gonorrhea	1	2
Graves Disease: Radioiodine therapy	1	2
Hypertension: Pulmonary	1	2
Hyperthyroidism	1	2
Influenza A	2	2
Insulin Resistance	1	2
Kidney Damage: Chemically-Induced	1	2
Lipid Peroxidation	1	2
Lung Injury: Smoke-Induced	1	2
Melanoma	1	2
Mercury Poisoning	1	2
Myocardial Infarction	1	2
Oral Cancer	2	2
Pain	1	2
Peptic Ulcer	1	2
Prenatal Chemical Exposures	1	2
Prostate Cancer	2	2
Pseudomonas aeruginosa	2	2
Radiation-Induced Illness: Radioiodine (Iodine-131)	1	2
Sciatica	1	2
Skin Diseases	1	2
Staphylococcus epidermidis	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Avian Influenza	1	1
Brain Ischemia	1	1
Breast Cancer	1	1
Candida Infection	1	1
Carcinoma: Non-Small-Cell Lung	1	1
Dengue	1	1
Enterococcus Infections	1	1
Gastric Cancer	1	1
H1N1 Infection	1	1
Head and Neck Cancer	1	1
Iron Overload	1	1
Mastitis	1	1
Metabolic Syndrome X	1	1
Mycobacterium tuberculosis	1	1
Non-Small-Cell Lung Carcinoma	1	1
Photooxidative Stress	1	1
Pneumonia	1	1
Radiotherapy	1	1
Staphylococcus aureus: Methicillin-resistant (MRSA)	1	1
Streptococcus pyogenes	1	1
Ultraviolet Radiation Induced Damage	1	1
Cataract	1	0

Name	AC	CK
Antimicrobial	11	39
Neuroprotective Agents	12	31
Antioxidants	14	29
Anti-Inflammatory Agents	14	27
Anti-Bacterial Agents	5	23
Radioprotective	12	19
Antiviral Agents	9	18
Hepatoprotective	2	12
Anti-Fibrotic	1	10
Anticarcinogenic Agents	1	10
Apoptotic	9	10
anti-inflammatory	1	10
Hypoglycemic Agents	5	9
Anti-metastatic	5	7
Hypolipidemic	3	6
Tumor Necrosis Factor (TNF) Alpha Inhibitor	3	5
Antiproliferative	3	4
Immunomodulatory	3	4
Leishmanicidal	2	4
Analgesics	2	3
Cardioprotective	2	3
NF-kappaB Inhibitor	2	3
Acetylcholinesterase Inhibitor	1	2
Angiogenesis Inhibitors	2	2
Anti-Anxiety Agents	1	2
Anti-Ulcer Agents	1	2
Anti-pyretic	1	2
Antifungal Agents	2	2
Antihypertensive Agents	1	2
Bcl-2 protein down-regulation	2	2
Chemopreventive	2	2
Chemotherapeutic	2	2
Cytoprotective	1	2
Glutathione Upregulation	1	2
Matrix metalloproteinase-9 (MMP-9) inhibitor	2	2
Renoprotective	1	2
Alpha-amylase inhibitor	1	1
Anti-Apoptotic	1	1
Antineoplastic Agents	1	1
Antinoceceptive	1	1
Bax/Bcl2 ratio: Increase	1	1
Caspase-3 Activation	1	1
Caspase-9 Activation	1	1
Interleukin-1 beta downregulation	1	1
Interleukin-6 Downregulation	1	1
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	1
PI3K/Akt/signaling suppression	1	1
Phase II Detoxification Enzyme Inducer	1	1
Photoprotective	1	1
Radiosensitizer	1	1
Tumor Suppressor Protein p53 Upregulation	1	1
Vascular Endothelial Growth Factor Inhibitors	1	1

[+]

Antibacterial efficacy of manuka honey, ocimum sanctum, curcuma longa and 0.2% chlorhexidine mouthwash on the level of streptococcus mutans.Mar 31, 2022

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Pubmed Data : J Ayurveda Integr Med. 2014 Apr ;5(2):109-16. PMID: 24948862

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Pubmed Data : Indian J Exp Biol. 2015 Oct ;53(10):632-40. PMID: 26665293

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Pubmed Data : Methods Find Exp Clin Pharmacol. 2007 Jul-Aug;29(6):411-6. PMID: 17922070

Article Published Date : Jul 01, 2007

Study Type : Animal Study

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Substances : Holy Basil

Diseases : Oxidative Stress, Stress

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Holy basil possesses potent anti-ulcerogenic and ulcer-healing properties.Aug 01, 2004

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Pubmed Data : J Ethnopharmacol. 2004 Aug;93(2-3):197-206. PMID: 15234753

Article Published Date : Aug 01, 2004

Study Type : Animal Study

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Substances : Holy Basil

Diseases : Duodenal Ulcer, Gastric Ulcer, Peptic Ulcer

Pharmacological Actions : Anti-Ulcer Agents

Additional Keywords : Plant Extracts

[+]

Inhalation of low-dose basil essential oil improved cardiovascular health and plasma lipid markers in high fat diet-induced obesity.May 31, 2022

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Pubmed Data : J Food Sci. 2022 Jun ;87(6):2450-2462. Epub 2022 May 19. PMID: 35591766

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Pubmed Data : Pharmacogn Rev. 2015 Jul-Dec;9(18):87-92. PMID: 26392704

Article Published Date : Jun 30, 2015

Study Type : Review

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Substances : Curry Leaves, Eucalyptus, Guava, Hibiscus sabdariffa , Holy Basil, Mangifera indica , Neem

Diseases : Dental Caries, Periodontal Diseases, Streptococcus Infections

Pharmacological Actions : Antimicrobial

[+]

A crude extract and terpenoid isolated from the leaves of O. sanctum and polyphenol from A. arabica shows promising antiviral effects against H9N2 virus.Jun 04, 2018

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Pubmed Data : J Inflamm Res. 2021 ;14:869-884. Epub 2021 Mar 16. PMID: 33758527

Article Published Date : Dec 31, 2020

Study Type : In Vitro Study

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Substances : Ashwagandha, Guduchi , Holy Basil

Diseases : Coronavirus Infection

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

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Pubmed Data : Adv Neurobiol. 2016;12:107-123. PMID: 27651251

Article Published Date : Dec 31, 2015

Study Type : Review

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Substances : Amla Fruit, Ashwagandha, Bacopa, Gotu Kola, Holy Basil, Spikenard, Turmeric

Diseases : Alzheimer's Disease, Neurodegenerative Diseases, Parkinson's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

[+]

Holy basil (O. sanctum) contains compounds with cyclooxygenase enzyme (inflammation) inhibitory activity comparable to ibuprofen, naproxen and aspirin. Mar 01, 2000

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Pubmed Data : Phytomedicine. 2000 Mar;7(1):7-13. PMID: 10782484

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Pubmed Data : Front Mol Biosci. 2021 ;8:637329. Epub 2021 Jul 2. PMID: 34277698

Article Published Date : Dec 31, 2020

Study Type : In Vitro Study

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Substances : Coriandrum sativum, Holy Basil, Mint

Diseases : Coronavirus Infection

Pharmacological Actions : Antiviral Agents

[+]

Iron modulatory property of a polysaccharide from Indian medicinal plant Ocimum sanctum.Jan 05, 2021

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Pubmed Data : Free Radic Res. 2021 Jan 6:1-10. Epub 2021 Jan 6. PMID: 33327808

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Pubmed Data : Curr Eye Res. 2005 Jul;30(7):583-91. PMID: 16020293

Article Published Date : Jul 01, 2005

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Substances : Holy Basil

Diseases : Cataract

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View the Evidence: 109 Abstracts with Holy Basil Research

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Antibacterial efficacy of manuka honey, ocimum sanctum, curcuma longa and 0.2% chlorhexidine mouthwash on the level of streptococcus mutans.Mar 31, 2022

Ayurvedic treatment can expedite virological clearance, help in faster recovery and concomitantly reduce the risk of viral dissemination.Mar 31, 2021

Efficacy of topical tulsi paste for the management of oral submucous fibrosis.Mar 31, 2022

Holy Basil (Ocimum sanctum) significantly improves symptoms in Generalized Anxiety Disorder. Sep 01, 2008

Holy basil leaf extract seems to have potential cognition-enhancing properties in humans.Dec 31, 2014

Holy basil was found to be equally effective in reducing periodontal indices as chlorhexidine yet with no side effects.Mar 31, 2014

O. sanctum and A. vera may prove to be as effective as chlorhexidine mouthwash.Dec 31, 2018

These observations clearly indicate the beneficial effects of O. sanctum on various biochemical parameters in young overweight or obese subjects.Jun 30, 2017

Tulsi and turmeric offers a safe and efficacious combination of natural products available for symptomatic treatment of oral submucous fibrosis.Dec 31, 2014

Tulsi has stood the test and is as effective as Chlorhexidine and Listerine in reducing the salivary S. mutans levels.Oct 31, 2011

Tulsi has the potential to be developed into an antimicrobial agent against cariogenic bacteria, specifically S. mutans.Dec 31, 2018

Tulsi is effective in reducing halitosis, plaque and gingivitis.Apr 30, 2019

Administration of O. sanctum ethanolic extract may stimulate and restore the expression of choline acetyltransferase on the deteriorating cells of HCMECs.Nov 30, 2016

A methanolic extract of Tulsi leaves could decrease inflammation in the cardiac tissue of isoproterenol induced myocardial infarction in rats.Sep 30, 2015

A polyherbal formula is comparable to the benzodiazepiene drug alprazolam in reducing ethanol withdrawal-induced anxiety behavior. Jan 01, 2011

Aloe vera, turmeric and holy basil suppress the adverse effects associated with maternal fluoride exposure. Aug 01, 2010

Amelioration of intracerebroventricular streptozotocin-induced cognitive dysfunction by Ocimum sanctum.Sep 30, 2022

Anti-Inflammatory and antimicrobial activities of fermented Ocimum sanctum extracts against skin and scalp microorganisms.Jan 31, 2022

Coconut and holy basil rescued the affected mice from the disease.Feb 28, 2017

Combination of Ocimum sanctum extract and Levetiracetam ameliorates cognitive dysfunction and hippocampal architecture in rat model of Alzheimer's disease.Dec 31, 2021

Effects of Ocimum tenuiflorum on induced testicular degeneration by filgrastim in wistar rats.Oct 31, 2021

Eugenol, an active component found within Ocimum sanctum (holy basil), is effective against Neisseria gonorrhoeae. Aug 01, 2008

Extracts of holy basil could become effective anti-amnesic treatments. Dec 03, 2016

Holy basil (O. sanctum) ameliorates sciatic nerve transection-induced neuropathy in rats. Oct 30, 2008

Holy basil (O. sanctum) has a protective effect against arsenic-induced toxicity in rats. Feb 01, 2009

Holy basil (O. sanctum) has a radioprotective effect on radiation damage caused by high-dose 131iodine exposure in mice. Aug 01, 2006

Holy basil (O. sanctum) improves survival of mice exposed to radiation. Jan 01, 1999

Holy basil (O. sanctum) prevents insulin resistance induced through a fructose-fed diet in rats. Jan 01, 2008

Holy basil (O. sanctum) prevents oxidative damage due to radiation and oxidizing agents. Jan 01, 2005

Holy basil (O. sanctum) protects against radiation injury through modulating glutathione and antioxidant enzymes. Mar 01, 1999

Holy basil (Ocimum sanctum) and clove protects against bacterial colonization of the lungs with Klebsiella pneumonia.Apr 01, 2009

Holy basil decreases T4 concentrations while improving antioxidant status in mice. Aug 01, 1998

Holy basil has anti-melanoma and radioprotective properties.Apr 01, 2011

Holy basil has significant anti-stress and antioxidant activity.Jul 01, 2007

Holy basil possesses potent anti-ulcerogenic and ulcer-healing properties.Aug 01, 2004

Inhalation of low-dose basil essential oil improved cardiovascular health and plasma lipid markers in high fat diet-induced obesity.May 31, 2022

Intraperitoneal administration of a water extract of holy basil had significant radio-protective abilities. Feb 28, 1995

Inula racemosa, Boerhaavia diffusa and Ocimum sanctum (Holy Basil) exhibited antiperoxidative, hypoglycaemic and cortisol lowering activities. Nov 01, 2004

Neuroprotective potential of ocimum sanctum leaf extract in preventing and attenuating stress induced substantia nigral neuronal damage.Dec 31, 2021

O. sanctum was found to be effective in the management of stress effects.Apr 30, 2016

Ocimum basilicum alleviates blood glucose, lipid profile and iNOS in diabetes gestational rat model.Apr 24, 2022

Ocimum sanctum (syn. Holy Basil) protects against mercury induced toxicity in mice. Sep 01, 2002

Ocimum sanctum ethanolic extract could be used to enhance cognitive ability.May 31, 2018

Ocimum sanctum has protective effects against smoke induced lung and neuronal tissue damage in rats.Jun 30, 2017

Ocimum sanctum Linn. extract improves cognitive deficits.Dec 31, 2020

Ocimum tenuiflorum L. may pave the way to the development of new agents for the treatment of diabetes and its complications.Mar 31, 2020

Pharmacological and pharmacokinetic effect of a polyherbal combination with Withania somnifera (L.) Dunal for the management of anxiety.Sep 02, 2020

Root extracts holy basil exhibits anti-inflammatory, analgesic and anti-pyretic activity.Apr 30, 2015

The present study demonstrates that Ocimum sanctum has therapeutic ability against monocrotaline-induced pulmonary hypertension.Apr 16, 2018

The protective effect of Ocimum sanctum leaf extract against lead acetate-induced nephrotoxicity and hepatotoxicity.Dec 31, 2020

These findings suggest a new option for antileishmanial chemotherapy at lower cost and nil toxicity.Jul 31, 2015

Treatment with fixed oil extracted from OS leaves significantly lowered the diabetically-elevated blood glucose levels and serum lipid profile.Feb 29, 2016

Ursolic acid and its isomer oleanolic acid are responsible for the anti-dementia effects of Ocimum sanctum.Feb 25, 2022

Vitamin E, turmeric and holy basil has significant radioprotective effects against Radioiodine-131 exposure in mice.Jun 01, 2010

This review is an attempt to assess the antimicrobial efficacy of 10 plant extracts on dental caries and plaque microorganisms.Jun 30, 2015

A crude extract and terpenoid isolated from the leaves of O. sanctum and polyphenol from A. arabica shows promising antiviral effects against H9N2 virus.Jun 04, 2018

A review of medicinal herbs in the treatment of neuropathic pain.Mar 31, 2018

An Aqueous extract of O. sanctum leaves was effective as an antiproliferative agent which caused apoptosis in oral cancer cell line.Dec 31, 2014

An extract of holy basil significantly inhibited cell adhesion and invasion at nontoxic concentrations.Dec 31, 2013

An in vitro study of Ocimum sanctum as a chemotherapeutic agent on oral cancer cell-line.Dec 31, 2020

Anti-cancer effects of novel flavonoid vicenin-2 as a single agent and in synergistic combination with docetaxel in prostate cancer.Oct 31, 2011

Anti-inflammatory, anti-oxidant effect and cytotoxicity of ocimum sanctum intra oral gel for combating periodontal diseases.Dec 31, 2019

Antifungal effects of tulsi, garlic, cinnamon and lemongrass in powder and oil form on Candida albicans.Apr 30, 2021

Antimicrobial efficiency of Tinospora cordifolia and Ocimum tenuiflorum against Streptococcus mutans and Candida albicans.Dec 31, 2021

Antiviral compound screening of natural compounds against influenza a virus (strain a/Puerto Rico/8/1934 H1N1).Sep 30, 2018

Apigenin could be a alternative to Oseltamivir and Zanamivir with improved predicted binding properties.Dec 31, 2014

Application of Ocimum leaf extract under drought stress can be a promising strategy to mitigate drought stress in rice. Feb 17, 2016

Comparative phytochemistry, antioxidant, antidiabetic, and anti-inflammatory activities of traditionally used basil.Dec 31, 2021

Coronil prevented SARS-CoV-2 S-protein mediated viral entry into A549 cells by inhibiting spike protein-ACE-2 interactions.Dec 31, 2020

Defining the role of isoeugenol from Ocimum tenuiflorum against diabetes mellitus-linked Alzheimer's disease.Apr 06, 2022

Ethanolic extract Ocimum sanctum induces an apoptosis in human lung adenocarcinoma (A549) cells.Oct 31, 2019

Ethanolic extract of O. sanctum leaf exerted its anti-invasive effect on head and neck squamous cell carcinoma cells by attenuating MMP activity.Jan 31, 2020

Holy Basil

View the Evidence:
109 Abstracts with Holy Basil Research