Insulin-like Growth Factor (IGF-1)

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5 Diseases Researched for Insulin-like Growth Factor (IGF-1)
NameACCKFocus
Amyotrophic Lateral Sclerosis47Locked
Motor Neuron Disease36Locked
Muscular Dystrophies12Locked
Peripheral Neuropathies12Locked
Excitotoxicity 11Locked
3 Pharmacological Actions Researched for Insulin-like Growth Factor (IGF-1)
NameACCKFocus
Neuroprotective Agents47Locked
Apoptotic23Locked
Neurorestorative12Locked

View the Evidence:
5 Abstracts with Insulin-like Growth Factor (IGF-1) Research

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Co-administration of IGF-I and glycosaminoglycans greatly delays motor neuron disease in the mouse model.Apr 01, 2002

Pubmed Data : J Neurochem. 2002 Apr;81(1):194-202. PMID: 12067233
Article Published Date : Apr 01, 2002
Study Type : Animal Study
Additional Links
Substances : Glycoaminoglycans, Insulin-like Growth Factor (IGF-1)
Diseases : Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Pharmacological Actions : Neuroprotective Agents
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Glycosaminoglycans boost insulin-like growth factor-I-promoted neuroprotection, indicating their potential value in motor neuron disease and peripheral neuropathies.Jan 01, 1999

Pubmed Data : Neuroscience. 1999;93(2):565-72. PMID: 10465440
Article Published Date : Jan 01, 1999
Study Type : Animal Study
Additional Links
Substances : Glycoaminoglycans, Insulin-like Growth Factor (IGF-1)
Diseases : Amyotrophic Lateral Sclerosis, Motor Neuron Disease, Peripheral Neuropathies
Pharmacological Actions : Apoptotic, Neuroprotective Agents
Additional Keywords : Drug Synergy
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Glycosaminoglycans co-administration enhance insulin-like growth factor-I neuroprotective and neuroregenerative activity in traumatic and genetic models of motor neuron disease.Jul 01, 2000

Pubmed Data : Int J Dev Neurosci. 2000 Jul-Aug;18(4-5):339-46. PMID: 10817918
Article Published Date : Jul 01, 2000
Study Type : Animal Study
Additional Links
Substances : Glycoaminoglycans, Insulin-like Growth Factor (IGF-1)
Diseases : Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Pharmacological Actions : Neuroprotective Agents, Neurorestorative
Additional Keywords : Natural Substance Synergy
[+]

IGF-1 improves fatigue resistance in the rat model of muscular dystrophy.Sep 01, 2004

Pubmed Data : Muscle Nerve. 2004 Sep;30(3):295-304. PMID: 15318340
Article Published Date : Sep 01, 2004
Study Type : Animal Study
Additional Links
Substances : Insulin-like Growth Factor (IGF-1)
Diseases : Muscular Dystrophies
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IGF-I prevents glutamate-induced motor neuron programmed cell death.Jan 15, 2009

Pubmed Data : Food Chem Toxicol. 2009 Jan 15. PMID: 15193297
Article Published Date : Jan 15, 2009
Study Type : In Vitro Study
Additional Links
Substances : Insulin-like Growth Factor (IGF-1)
Diseases : Amyotrophic Lateral Sclerosis, Excitotoxicity
Pharmacological Actions : Apoptotic, Neuroprotective Agents

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