Kahweol

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20 Diseases Researched for Kahweol

Name	AC	CK
Colorectal Cancer	3	7
Chemotherapy-Induced Kidney Damage	1	2
Chemotherapy-Induced Toxicity: Cisplatin	1	2
Diabetes Mellitus: Type 1	1	2
Diabetes Mellitus: Type 2	1	2
Bone Diseases	1	1
Breast Cancer	1	1
Breast Cancer: Triple Negative	1	1
Cancers: All	1	1
Inflammation	1	1
Kidney Cancer	1	1
Leukemia	1	1
Liver Cancer	1	1
Lung Cancer	1	1
Mesothelioma	1	1
Non-Small-Cell Lung Carcinoma	1	1
Oral Cancer	1	1
Osteoarthritis	1	1
Renal Cancer	1	1
Squamous cell carcinoma	1	1

26 Pharmacological Actions Researched for Kahweol

Name	AC	CK
Apoptotic	9	13
Bcl-2 protein down-regulation	4	8
Antiproliferative	7	7
Caspase-3 Activation	2	6
Heat Shock Protein Down-Regulation	1	5
Antioxidants	2	3
Chemoprotective Agents	1	2
Chemosensitizer	2	2
Heme oxygenase-1 up-regulation	1	2
Nrf2 activation	2	2
Pancreato Protective Agents	1	2
Renoprotective	1	2
Anti-Angiogenic	1	1
Anti-Inflammatory Agents	1	1
Anticarcinogenic Agents	1	1
Chemopreventive	1	1
Chemotherapeutic	1	1
Cyclin D1 Down-Regulation	1	1
Cyclooxygenase 2 Inhibitors	1	1
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	1
MicroRNA modulator	1	1
NF-kappaB Inhibitor	1	1
Osteogenic	1	1
Osteoprotective	1	1
Phase II Detoxification Enzyme Inducer	1	1
Tumor Suppressor Protein p53 Upregulation	1	1

Research Articles 16
Cumulative Knowledge Score 25
Overall Research Rating GOOD

View the Evidence:
16 Abstracts with Kahweol Research

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View the Evidence: 16 Abstracts with Kahweol Research

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Kahweol inhibits colorectal tumor cell growth by promoting apoptosis and suppressing HSP70 expression.Feb 28, 2015

Kahweol ameliorates cisplatin-induced acute kidney injury through pleiotropic effects.Dec 05, 2020

This study suggested that kahweol has anti-diabetic properties on pancreatic β-cells.Aug 25, 2021

Cafestol and kahweol are potential cancer treatments, or adjuvants as chemotherapeutic agents for malignant pleural mesothelioma.Jun 25, 2012

Cafestol may be a novel agent for bone diseases.Jun 30, 2015

Kahweol behaves as an anti-inflammatory and anti-angiogenic compound with potential use in antitumoral therapies.Dec 31, 2010

Kahweol induces apoptosis through ATF3-mediated pathway in human colorectal cancer cells.Nov 24, 2016

Kahweol inhibited A549 cell growth and induced apoptosis via down-regulation of STAT3 signaling pathway.May 21, 2009

Kahweol inhibited the proliferation of non-small cell lung cancer cells.Nov 30, 2016

Kahweol is an antitumor compound with inhibitory effects on tumor cell growth and survival, especially against MDA-MB231 breast cancer cells.May 08, 2014

Kahweol may be a potential anti-cancer which induces apoptotic cell death through down-regulation of Sp1 in oral squamous cell lines.Nov 30, 2014

Kahweol sensitizes renal carcinoma cells to TRAIL-induced apoptosis. Jun 06, 2010

Kahweol-mediated cyclin D1 degradation may contribute to the inhibition of the proliferation in human colorectal cancer cells.Aug 31, 2016

Melatonin sensitizes kidney cancer cells to kahweol-induced programmed cell death.Jan 18, 2011

The multifaceted mechanisms for coffee's anti-tumorigenic effect on liver.Oct 31, 2008

These results show the activity of kahweol to modulate multiple components in apoptotic response of human leukemia cells.Oct 31, 2009

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Kahweol

View the Evidence:
16 Abstracts with Kahweol Research