Kava Kava

Views 5243
Download the GMI DOC on this Topic

Sign in to Purchase/Download Documents

Sign in / Register

Focus Your Research

Click any topic below to filter + focus research
25 Diseases Researched for Kava Kava
NameACCKFocus
Anxiety Disorders15177Locked
Depression230Locked
Generalized Anxiety Disorder120Locked
Insomnia212Locked
Cancers: All211Locked
Cognitive Decline/Dysfunction110Locked
Mood Disorders110Locked
Perimenopausal Syndrome110Locked
Stress110Locked
Benzo[a]pyrene-induced Toxicity 24Locked
Lung Cancer24Locked
Phobia: Social13Locked
Phobias13Locked
Bladder Cancer22Locked
Inflammation22Locked
Alzheimer's Disease11Locked
Asthma11Locked
Cancers: Drug Resistant11Locked
Cocaine Withdrawal11Locked
Multiple Sclerosis11Locked
Neurodegenerative Diseases11Locked
Oxidative Stress11Locked
Prostate Cancer11Locked
Tobacco Addiction/Withdrawal11Locked
Urinary Tract Infections11Locked
16 Pharmacological Actions Researched for Kava Kava
NameACCKFocus
Anxiolytic774Locked
Antidepressive Agents110Locked
Antiproliferative 35Locked
Apoptotic34Locked
Chemopreventive24Locked
Antineoplastic Agents23Locked
Anti-Inflammatory Agents22Locked
Hypnotics and Sedatives12Locked
Neuroprotective Agents22Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor22Locked
Antioxidants11Locked
Cell cycle arrest11Locked
Cyclooxygenase 1 Inhibitor11Locked
Cyclooxygenase 2 Inhibitors11Locked
Endocannabinoid Modulator11Locked
NF-kappaB Inhibitor11Locked

View the Evidence:
42 Abstracts with Kava Kava Research

[+]

Ginkgo biloba, chamomile and kava kava exhibit therapeutic potential in generalizaed anxiety disorder.Oct 15, 2010

Pubmed Data : Rev Bras Psiquiatr. 2010 Oct 15. Epub 2010 Oct 15. PMID: 20963375
Article Published Date : Oct 15, 2010
Study Type : Meta Analysis
Additional Links
Substances : Chamomile, Ginkgo biloba, Kava Kava
Diseases : Generalized Anxiety Disorder
Additional Keywords : Benzodiazepine Alternatives, Benzodiazepine Receptor Agonist, Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs
[+]

Kava is an effective treatment alternative to pharmaceuticals in non-psychotic anxiety disorders.Mar 01, 2005

Pubmed Data : Phytother Res. 2005 Mar;19(3):183-8. PMID: 15934028
Article Published Date : Mar 01, 2005
Study Type : Meta Analysis
Additional Links
Substances : Kava Kava
Diseases : Anxiety Disorders, Depression
Additional Keywords : Plant Extracts
[+]

Kava Kava appears to be a short-term treatment for anxiety, but not a replacement for prolonged anti-anxiety use. Oct 31, 2018

Pubmed Data : Complement Ther Clin Pract. 2018 Nov ;33:107-117. Epub 2018 Sep 15. PMID: 30396607
Article Published Date : Oct 31, 2018
Study Type : Meta Analysis, Review
Additional Links
Substances : Kava Kava
Diseases : Anxiety Disorders
Pharmacological Actions : Anxiolytic
Additional Keywords : Plant Extracts
[+]

Meta-Analysis: Kava extract is superior to placebo as a symptomatic treatment for anxiety.Feb 01, 2000

Pubmed Data : J Clin Psychopharmacol. 2000 Feb;20(1):84-9. PMID: 10653213
Article Published Date : Feb 01, 2000
Study Type : Meta Analysis
Additional Links
Substances : Kava Kava
Diseases : Anxiety Disorders
Additional Keywords : Plant Extracts
[+]

Meta-Analysis: Kava is safe and superior to a placebo for treating anxiety. Jan 01, 2002

Pubmed Data : Cochrane Database Syst Rev. 2002(2):CD003383. PMID: 12076477
Article Published Date : Jan 01, 2002
Study Type : Meta Analysis
Additional Links
Substances : Kava Kava
Diseases : Anxiety Disorders
Additional Keywords : Plant Extracts
[+]

The current weight of evidence supports the use of kava in treatment of anxiety with a significant result occurring in four out of six studies reviewed.Jan 01, 2011

Pubmed Data : Aust N Z J Psychiatry. 2011 Jan;45(1):27-35. Epub 2010 Nov 15. PMID: 21073405
Article Published Date : Jan 01, 2011
Study Type : Meta Analysis
Additional Links
Substances : Kava Kava
Diseases : Anxiety Disorders
Pharmacological Actions : Anxiolytic
[+]

Kava and valerian root are effective in the treatment of stress-induced insomnia. Sep 01, 2001

Pubmed Data : Phytother Res. 2001 Sep;15(6):549-51. PMID: 11536390
Article Published Date : Sep 01, 2001
Study Type : Human Study
Additional Links
Substances : Kava Kava, Valerian
Diseases : Insomnia, Stress
[+]

Kava appears safe and effective for anxiety disorders. Jun 01, 2009

Pubmed Data : Complement Ther Med. 2009 Jun;17(3):176-8. Epub 2009 Feb 7. PMID: 19398072
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Substances : Kava Kava
Diseases : Anxiety Disorders
[+]

Kava enhances cognitive performance and cheerful mood.Jun 01, 2004

Pubmed Data : Hum Psychopharmacol. 2004 Jun;19(4):243-50. PMID: 15181652
Article Published Date : Jun 01, 2004
Study Type : Human Study
Additional Links
Substances : Kava Kava
Diseases : Anxiety Disorders, Cognitive Decline/Dysfunction, Mood Disorders
Additional Keywords : Plant Extracts, Superio+
[+]

Kava is effective in treating perioperative anxiety. Jan 01, 2000

Pubmed Data : Zentralbl Gynakol. 2000;122(11):561-5. PMID: 11127769
Article Published Date : Jan 01, 2000
Study Type : Human Study
Additional Links
Substances : Kava Kava
Diseases : Anxiety Disorders
Additional Keywords : Plant Extracts
[+]

Kava is safe and effective in treating anxiety disorders and depression.Aug 01, 2009

Pubmed Data : Psychopharmacology (Berl). 2009 Aug;205(3):399-407. Epub 2009 May 9. PMID: 19430766
Article Published Date : Aug 01, 2009
Study Type : Human Study
Additional Links
Substances : Kava Kava
Diseases : Anxiety Disorders, Depression
Pharmacological Actions : Antidepressive Agents, Anxiolytic
Additional Keywords : Plant Extracts
[+]

Kava was judged to be an effective and safe treatment of non-psychotic anxiety syndrome.Apr 01, 2004

Pubmed Data : Phytother Res. 2004 Apr;18(4):297-300. PMID: 15162364
Article Published Date : Apr 01, 2004
Study Type : Human Study
Additional Links
Substances : Kava Kava
Diseases : Anxiety Disorders
Pharmacological Actions : Anxiolytic
[+]

Kava was judged to be well-tolerated and as effective as Buspirone and Opipramol in the acute treatment of out-patients suffering from Generalized Anxiety Disorder.Jan 01, 2003

Pubmed Data : Phytomedicine. 2003;10 Suppl 4:38-49. PMID: 12807341
Article Published Date : Jan 01, 2003
Study Type : Human Study
Additional Links
Substances : Kava Kava
Diseases : Anxiety Disorders
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Kava was judged to improve the mood, particularly by reducing anxiety in perimenopausal women.Dec 01, 2008

Pubmed Data : Integr Cancer Ther. 2008 Dec;7(4):295-310. PMID: 12590005
Article Published Date : Dec 01, 2008
Study Type : Human Study
Additional Links
Substances : Kava Kava
Diseases : Anxiety Disorders, Perimenopausal Syndrome
Pharmacological Actions : Anxiolytic
[+]

Safety Study: No evidence for irreversible liver damage has been found in kava users.Jan 01, 2003

Pubmed Data : J Toxicol Clin Toxicol. 2003;41(6):821-9. PMID: 14677792
Article Published Date : Jan 01, 2003
Study Type : Human Study
Additional Links
Substances : Kava Kava
Additional Keywords : Plant Extracts
[+]

There is a close inverse relationship between cancer incidence and kava consumption.Nov 01, 2000

Pubmed Data : Hawaii Med J. 2000 Nov;59(11):420-2. PMID: 11149250
Article Published Date : Nov 01, 2000
Study Type : Human Study
Additional Links
Substances : Kava Kava
Diseases : Cancers: All
[+]

Case study: Kava is effective in the treatment of anxiety disorder, simple phobia and specific social phobia. Nov 01, 2001

Pubmed Data : Phytother Res. 2001 Nov;15(7):646-7. PMID: 11746854
Article Published Date : Nov 01, 2001
Study Type : Human: Case Report
Additional Links
Substances : Kava Kava
Diseases : Anxiety Disorders, Phobia: Social, Phobias
Additional Keywords : Plant Extracts
[+]

Kava compares favorably with diazepam in reducing anxiety in mice. Jun 01, 2002

Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2002 Jun;26(5):855-60. PMID: 12369257
Article Published Date : Jun 01, 2002
Study Type : Animal Study
Additional Links
Substances : Kava Kava
Diseases : Anxiety Disorders
Pharmacological Actions : Anxiolytic
Additional Keywords : Benzodiazepine Alternatives, Plant Extracts, Superiority of Natural Substances versus Drugs
[+]

Kava exhibits anxiolytic properties in mice.Oct 01, 2003

Pubmed Data : Psychopharmacology (Berl). 2003 Oct;170(1):33-41. Epub 2003 Jul 4. PMID: 12845414
Article Published Date : Oct 01, 2003
Study Type : Animal Study
Additional Links
Substances : Kava Kava
Diseases : Anxiety Disorders
Pharmacological Actions : Anxiolytic
Additional Keywords : Plant Extracts
[+]

Kava exhibits chemopreventive properties in chemically-induced lung cancer.Nov 01, 2008

Pubmed Data : Cancer Prev Res (Phila). 2008 Nov;1(6):430-8. PMID: 19138990
Article Published Date : Nov 01, 2008
Study Type : Animal Study
Additional Links
Substances : Kava Kava
Diseases : Benzo[a]pyrene-induced Toxicity , Lung Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Chemopreventive
Additional Keywords : Plant Extracts
[+]

Kava kava improves sleep quality in sleep-disturbed rats.Jul 01, 2005

Pubmed Data : Psychopharmacology (Berl). 2005 Jul;180(3):564-9. Epub 2005 Feb 8. PMID: 15700178
Article Published Date : Jul 01, 2005
Study Type : Animal Study
Additional Links
Substances : Kava Kava
Diseases : Insomnia
Pharmacological Actions : Hypnotics and Sedatives
Additional Keywords : Plant Extracts
[+]

Safety Study: Aqueous kava extracts do not affect liver function tests in rats.Jun 01, 2003

Pubmed Data : Planta Med. 2003 Jun;69(6):496-9. PMID: 12865965
Article Published Date : Jun 01, 2003
Study Type : Animal Study
Additional Links
Substances : Kava Kava
Additional Keywords : Plant Extracts
[+]

Safety Study: chronic ethanolic kava extract is safe in rats.Sep 01, 2006

Pubmed Data : Phytomedicine. 2006 Sep;13(8):542-9. Epub 2006 Aug 14. PMID: 16904878
Article Published Date : Sep 01, 2006
Study Type : Animal Study
Additional Links
Substances : Kava Kava
Additional Keywords : Herb Safety, Plant Extracts
[+]

Safety Study: Kava does not produce or aggravte liver injury.Jul 01, 2007

Pubmed Data : Food Chem Toxicol. 2007 Jul;45(7):1293-300. Epub 2007 Jan 26. PMID: 17353074
Article Published Date : Jul 01, 2007
Study Type : Animal Study
Additional Links
Substances : Kava Kava
Additional Keywords : Drug Synergy, Plant Extracts
[+]

A review of herbal therapy in multiple sclerosis.Oct 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Pharm Bull. 2018 Nov ;8(4):575-590. Epub 2018 Nov 29. PMID: 30607330
Article Published Date : Oct 31, 2018
Study Type : Review
Additional Links
Substances : Cannabis, Cranberry, Frankincense, Ginger, Ginkgo biloba, Ginseng, Grape, Kava Kava, Nigella sativa (aka Black Seed), Saffron, St. Johns Wort, Turmeric, Valerian
Diseases : Multiple Sclerosis
[+]

A review of plants and substances that can modulate the endocannabinoid system.May 10, 2016

Pubmed Data : Trends Pharmacol Sci. 2016 May 11. Epub 2016 May 11. PMID: 27179600
Article Published Date : May 10, 2016
Study Type : Review
Additional Links
Substances : Black Pepper, Chocolate, Kava Kava
Pharmacological Actions : Endocannabinoid Modulator
[+]

Kava contains a compound inhibits the growth of bladder cancer cells. Nov 01, 2008

Pubmed Data : Cancer Prev Res (Phila). 2008 Nov;1(6):439-51. PMID: 19138991
Article Published Date : Nov 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Kava Kava
Diseases : Bladder Cancer, Cancers: Drug Resistant
Pharmacological Actions : Antineoplastic Agents, Cell cycle arrest
[+]

Kava contains a compound which induces programmed cell death in bladder cancer cells. Apr 15, 2005

Pubmed Data : Cancer Res. 2005 Apr 15;65(8):3479-86. PMID: 15833884
Article Published Date : Apr 15, 2005
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Kava Kava
Diseases : Bladder Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Plant Extracts
[+]

Kava contains a compound which induces programmed cell death in prostate cancer cells.Jun 01, 2007

Pubmed Data : Indian J Exp Biol. 2007 Jun;45(6):524-8. PMID: 20112340
Article Published Date : Jun 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Kava Kava
Diseases : Prostate Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Kava contains a compound which protects against neurodegeneration. May 01, 2010

Pubmed Data : Bioorg Med Chem. 2010 May 1;18(9):3133-9. Epub 2010 Mar 20. PMID: 20371185
Article Published Date : May 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Kava Kava
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Kava contains compounds with Cyclooxygenase enzyme inhibitory and antioxidant properties.Jan 01, 2002

Pubmed Data : Phytomedicine. 2002 Jan;9(1):41-7. PMID: 11924763
Article Published Date : Jan 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Kava Kava
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors
Additional Keywords : Plant Extracts
[+]

Kava contains compunds which protect neural cells against Alzheimer associated amyloid beta-peptide induced neurotoxicity.Jun 01, 2008

Pubmed Data : Mol Pharmacol. 2008 Jun;73(6):1785-95. Epub 2008 Mar 11. PMID: 18334601
Article Published Date : Jun 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Kava Kava
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Kava has anti-inflammatory properties used in traditional Fijian medicine to treat urinary tract infections and asthma.Apr 14, 2006

Pubmed Data : Biochem Pharmacol. 2006 Apr 14;71(8):1206-18. Epub 2006 Feb 7. PMID: 16464438
Article Published Date : Apr 14, 2006
Study Type : In Vitro Study
Additional Links
Substances : Kava Kava
Diseases : Asthma, Inflammation, Urinary Tract Infections
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Science Confirms Tradition
[+]

Kava may contribute to ameliorating cravings in drug addiction. Sep 01, 2001

Pubmed Data : Pac Health Dialog. 2001 Sep;8(2):335-9. PMID: 12180513
Article Published Date : Sep 01, 2001
Study Type : Review
Additional Links
Substances : Kava Kava
Diseases : Cocaine Withdrawal, Tobacco Addiction/Withdrawal
[+]

Safety Study: Kava does not display metabolic toxicity in a homogeneous cellular assay.Apr 01, 2004

Pubmed Data : Planta Med. 2004 Apr;70(4):289-92. PMID: 15095141
Article Published Date : Apr 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Kava Kava
Additional Keywords : Plant Extracts
[+]

Safety Study: Kava has a superior "risk-to-benefit" ratio compared to other drugs used to treat anxiety.Apr 15, 2004

Pubmed Data : Toxicol Lett. 2004 Apr 15;150(1):85-96. PMID: 15068826
Article Published Date : Apr 15, 2004
Study Type : Review
Additional Links
Substances : Kava Kava
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Safety Study: The association between kava use and liver toxicity appears to be weak. Oct 01, 2010

Pubmed Data : J Clin Pharm Ther. 2010 Oct;35(5):545-63. PMID: 20831679
Article Published Date : Oct 01, 2010
Study Type : Review
Additional Links
Substances : Kava Kava
[+]

The consumption of Kava by Fijians may contribute to their unusually low levels of cancer.May 01, 2003

Pubmed Data : Phytomedicine. 2003 May;10(4):309-17. PMID: 12809361
Article Published Date : May 01, 2003
Study Type : Review
Additional Links
Substances : Kava Kava
Diseases : Cancers: All
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Kava is well tolerated effective against female climacteric (menopausal) symptoms.Feb 10, 1991

Pubmed Data : Fortschr Med. 1991 Feb 10;109(4):119-22. PMID: 2029982
Article Published Date : Feb 10, 1991
Additional Links
Substances : Kava Kava
[+]

Kava may exert its favourable effects on anxiety by improving baroflex control of heart rate.Dec 01, 2001

Pubmed Data : J Psychopharmacol. 2001 Dec;15(4):283-6. PMID: 11769822
Article Published Date : Dec 01, 2001
Additional Links
Substances : Kava Kava
[+]

Kava was judged to be a safe and effective treatment for sleep disturbances associated with non-psychotic anxiety disorders.Feb 01, 2004

Pubmed Data : J Affect Disord. 2004 Feb;78(2):101-10. PMID: 14706720
Article Published Date : Feb 01, 2004
Additional Links
Substances : Kava Kava
[+]

Kava was judged to have a beneficial effect in the treatment of anxiety, tension and restlessness, without having any adverse effect on the liver.Nov 01, 2003

Pubmed Data : Phytomedicine. 2003 Nov;10(8):631-9 PMID: 14692723
Article Published Date : Nov 01, 2003
Additional Links
Substances : Kava Kava

Kava Kava Related Articles

Calm Anxiety Naturally: 7 Top Substances
Written by GreenMedInfo Research Group
In the face of the mounting costs of anxiety in the U.S. and globally, here are seven substances that act as natural anti-anxiety agents and may make a difference in addressing the unprecedented levels of stress people are facing today, in the wake of the COVID crisis.
Can Kava Boost Your Mood?
Written by GreenMedInfo Research Group
Kava, a plant native to the South Pacific islands, has been valued for its calming properties since ancient times. Sipping on traditional kava tea may reduce tension while kava extract has been linked to increased cheerful mood, anxiety relief and more
A 3,000 Year Old Herbal Remedy for Anxiety Puts Drugs to Shame in Landmark Clinical Trial
Written by GMI Reporter
From racing thoughts to restless dread, anxiety’s distress calls for soothing relief. Now research on an ancient South Pacific herb brings hope for those looking for safer natural alternatives.
23 Natural Alternatives for Depression
Written by Pat Robinson
There are a broad range of evidence-based natural alternatives for depression. GreenMedInfo.com sources its research from the public domain, namely, the National Library of Medicine's bibliographic database known as Medline

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.
  • Printer-friendly version

Connect with GreenMedInfo

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2025 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.