Kefir

Name	AC	CK
Inflammation	9	34
Obesity	9	33
Colitis	5	28
Breast Cancer	5	25
Insulin Resistance	2	23
Cardiovascular Diseases	4	22
Colon Cancer	3	22
Hyperglycemia	2	21
Oxidative Stress	12	21
Inflammatory Bowel Diseases	4	16
Alzheimer's Disease	3	12
Diabetes Mellitus: Type 2	2	12
Fatigue: Excercise-Induced	2	12
Metabolic Syndrome X	2	12
Cancers: All	2	11
Athletic Performance: Recovery	1	10
Atopic Dermatitis	1	10
C-Reactive Protein	1	10
Constipation	1	10
Depression: Postmenopausal	1	10
Osteoporosis	5	10
Polycystic Ovary Syndrome	1	10
Postmenopausal Disorders	1	10
Postmenopausal Disorders: Insomnia	1	10
Nonalcoholic fatty liver disease (NAFLD)	5	9
Gastric Ulcer	3	6
High Fat Diet	3	6
Salmonella Infections	3	5
Atherosclerosis	2	4
Depression	2	4
Ehrlich carcinoma	2	4
High Fructose Diet	2	4
Hypertension	2	4
Ischemia	2	4
Radiation	2	4
Burns	2	3
Colorectal Cancer	2	3
Colorectal Cancer: Prevention	2	3
Encephalitis	1	3
Food Allergies	2	3
Hypercholesterolemia	2	3
Liver Damage	2	3
Neurodegenerative Diseases	3	3
Staphylococcus aureus infection	2	3
Wound Healing	2	3
Acute Myeloid Leukemia	2	2
Aging	1	2
Air Pollution Linked Toxicity	1	2
Alcohol Toxicity	1	2
Alcoholic Liver Disease	1	2
Antibiotic Toxicity	1	2
Anxiety	1	2
Arthritis	1	2
Autism Spectrum Disorders	1	2
Bisphenol Toxicity	1	2
Brain Inflammation	1	2
Cardiac Hypertrophy	1	2
Chemically-Induced Liver Damage	1	2
Chemotherapy-Induced Toxicity: Bleomycin	1	2
Chemotherapy-Induced Toxicity: Doxorubicin	1	2
Chronic Kidney Disease (CKD)	1	2
Clostridium Infections	1	2
Drug-Induced Toxicity: Indomethacin	1	2
Dysbiosis	1	2
Fatty Liver	1	2
Gastrointestinal Inflammation	1	2
Hemophilia	1	2
Hepatic Steatosis	1	2
Hyperlipidemia	1	2
Kidney Damage	1	2
Leukemia	2	2
Lipid Peroxidation	1	2
Lipopolysaccharide-Induced Toxicity	1	2
Lung Inflammation	1	2
Mycotoxin Toxicity	1	2
Myocardial Infarction	1	2
Periodontitis	1	2
Pseudomonas aeruginosa	1	2
Radiation Induced Illness	1	2
Rheumatoid Arthritis	1	2
Scars	1	2
Smoking Cessation: Nicotine Addiction	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Bacillus Cereus infection	1	1
Bacterial Infections	1	1
Cancers: Drug Resistant	1	1
Cancers: Multi-Drug Resistant	1	1
Coronavirus Infection	1	1
Dementia	1	1
Dyslipidemias	1	1
Escherichia coli Infections	1	1
Gastric Cancer	1	1
Glioblastoma	1	1
Human T-Cell Lymphotrophic Virus type 1 associated disease	1	1
Hydrogen Peroxide Induced Toxicity	1	1
Leukemia: Chronic myelogenous leukemia (CML)	1	1
Listeria Infections	1	1
Metabolic Diseases	1	1
Parkinson's Disease	1	1
Skin Cancer	1	1
Vibrio parahaemolyticus	1	1

Name	AC	CK
Anti-Inflammatory Agents	40	150
Antioxidants	29	79
Gastrointestinal Agents	24	77
Tumor Necrosis Factor (TNF) Alpha Inhibitor	15	45
Hypoglycemic Agents	5	35
Immunomodulatory	7	29
Gastroprotective	6	28
Antimicrobial	3	22
Insulin Sensitizers	1	21
Interleukin-6 Downregulation	10	19
Hypolipidemic	5	18
Interleukin-1 beta downregulation	9	17
Neuroprotective Agents	6	17
Antidepressive Agents	4	16
Antihypertensive Agents	2	12
Interleukin-8 downregulation	2	12
Chemotherapeutic	2	11
Anti-Bacterial Agents	6	10
Apoptotic	7	10
Interferon Gamma Reducer	1	10
Laxative	1	10
Cardioprotective	5	9
Hepatoprotective	5	9
Osteoprotective	4	8
Superoxide Dismutase Up-regulation	5	8
Chemopreventive	4	7
Malondialdehyde Down-regulation	4	7
Anti-Apoptotic	4	6
Interleukin-10 downregulation	3	6
Renoprotective	3	6
Antiproliferative	4	5
Anti-Anxiety Agents	2	4
Anti-Fibrotic	2	4
Anti-Ulcer Agents	2	4
Chemoprotective Agents	2	4
Interleukin-10 upregulation	2	4
NF-kappaB Inhibitor	2	4
Radioprotective	2	4
Anticarcinogenic Agents	2	3
Antineoplastic Agents	1	2
Bcl-2 protein down-regulation	2	2
Brain-derived neurotrophic factor modulator	1	2
Cyclooxygenase 2 Inhibitors	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	2
Nitric Oxide Inhibitor	1	2
Osteogenic	1	2
Prophylactic Agents	1	2
anti-inflammatory	1	2
Angiotensin-Converting Enzyme Inhibitors	1	1
Anti-Allergic Agents	1	1
Anti-Angiogenic	1	1
Anticholesteremic Agents	1	1
Antimutagenic Agents	1	1
Catalase Up-Regulation	1	1

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Kefir has a beneficial effect in decreasing insulin resistance.Dec 31, 2022

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Pubmed Data : Curr Drug Targets. 2023 ;24(7):599-612. PMID: 37102491

Article Published Date : Dec 31, 2022

Study Type : Meta Analysis, Review

Additional Links

Substances : Kefir

Diseases : Insulin Resistance

Pharmacological Actions : Insulin Sensitizers

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Bioactive compounds from kefir and their potential benefits on health.Dec 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Turk J Gastroenterol. 2019 Jan 21. Epub 2019 Jan 21. PMID: 30662004

Article Published Date : Jan 20, 2019

Study Type : Human Study

Additional Links

Substances : Kefir

Diseases : Inflammatory Bowel Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective

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Effects of kefir consumption on gut microbiota and health outcomes in women with polycystic ovary syndrome.Jul 31, 2024

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Pubmed Data : J Clin Lipidol. 2017 Jan - Feb;11(1):136-146. Epub 2016 Nov 9. PMID: 28391880

Article Published Date : Jan 31, 2017

Study Type : Human Study

Additional Links

Substances : Kefir

Diseases : Obesity

Pharmacological Actions : Hypolipidemic

Additional Keywords : Anti-Obesity Agents

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Kefir has positive effects on sleep disturbances, depression, and quality of life in postmenopausal women.Dec 31, 2018

Pubmed Data : J Dairy Sci. 2015 Nov ;98(11):7446-9. Epub 2015 Aug 20. PMID: 26298752

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Pubmed Data : Nutrition. 2018 Jul - Aug;51-52:66-72. Epub 2018 Feb 7. PMID: 29605766

Article Published Date : Jul 31, 2018

Study Type : Animal Study

Additional Links

Substances : Kefir

Diseases : Cardiac Hypertrophy, Hypertension

Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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AB-kefir reduced body weight and ameliorated inflammation in adipose tissue of obese mice fed a high-fat diet.Jun 23, 2021

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Pubmed Data : Nutrients. 2021 Jun 24 ;13(7). Epub 2021 Jun 24. PMID: 34202894

Article Published Date : Jun 23, 2021

Study Type : Animal Study

Additional Links

Substances : Kefir

Diseases : High Fat Diet

Pharmacological Actions : Anti-Inflammatory Agents

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Administration of kefir in myocardial infarction induced by isoproterenol can protect the heart and minimize the toxic damage.Mar 31, 2018

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Pubmed Data : Korean J Food Sci Anim Resour. 2018 Apr ;38(2):259-272. Epub 2018 Apr 30. PMID: 29805276

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Pubmed Data : J Nutr Biochem. 2017 06 ;44:35-43. Epub 2017 Mar 4. PMID: 28384519

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Pubmed Data : J Med Food. 2008 Jun;11(2):356-61. PMID: 18598180

Article Published Date : Jun 01, 2008

Study Type : Animal Study

Additional Links

Substances : Kefir

Diseases : Scars

Additional Keywords : Cicatrization

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Kefir has a protective effect against bone loss, deterioration of trabecular microarchitecture, and biomechanical dysfunction.Jan 31, 2015

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Pubmed Data : Osteoporos Int. 2015 Feb ;26(2):589-99. Epub 2014 Oct 3. PMID: 25278298

Article Published Date : Jan 31, 2015

Study Type : Animal Study

Additional Links

Substances : Kefir, Milk: Fermented

Diseases : Osteoporosis

Pharmacological Actions : Osteogenic

Additional Keywords : Significant Treatment Outcome

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Published Date : Jul 31, 2017

Study Type : Animal Study

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Substances : Kefir

Diseases : Salmonella Infections

Pharmacological Actions : Anti-Bacterial Agents

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Lactobacillus mali ameliorated hepatic steatosis by modulating lipid metabolism and antioxidant activity.Dec 31, 2017

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Pubmed Data : Mol Nutr Food Res. 2018 04 ;62(8):e1700903. Epub 2018 Apr 3. PMID: 29508520

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Pubmed Data : Biomed Pharmacother. 2021 Jul ;139:111677. Epub 2021 May 6. PMID: 33965727

Article Published Date : Jun 30, 2021

Study Type : Animal Study

Additional Links

Substances : Kefir

Diseases : Inflammation, Periodontitis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Novel kefir exopolysaccharides mitigate lipopolysaccharide-induced systemic inflammation.Sep 04, 2023

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Pubmed Data : Food Funct. 2023 Jul 31 ;14(15):6813-6827. Epub 2023 Jul 31. PMID: 37449473

Article Published Date : Jul 30, 2023

Study Type : Animal Study

Additional Links

Substances : Kefir

Diseases : Colitis, Inflammatory Bowel Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Gastrointestinal Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Probiotic kefir was able to attenuate the molecular, structural, and physiological cardiovascular changes induced by BPA.Oct 24, 2019

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Pubmed Data : J Nutr Biochem. 2019 Oct 25 ;75:108254. Epub 2019 Oct 25. PMID: 31707283

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Pubmed Data : Nutr Cancer. 2020 Apr 30:1-7. Epub 2020 Apr 30. PMID: 32351133

Article Published Date : Apr 29, 2020

Study Type : Animal Study

Additional Links

Substances : Kefir, Vitamin C

Diseases : Radiation

Pharmacological Actions : Antioxidants, Radioprotective

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The results of this study suggest that kefir peptides ameliorate salt-induced renal damage.Aug 25, 2020

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Use of kefir peptide (Kef-1) as an emerging approach for the treatment of oxidative stress and inflammation in 2K1C mice.Feb 20, 2022

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Pubmed Data : Food Funct. 2022 Feb 21 ;13(4):1965-1974. Epub 2022 Feb 21. PMID: 35088783

Article Published Date : Feb 20, 2022

Study Type : Animal Study

Additional Links

Substances : Kefir

Diseases : Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

A polysaccharide extract obtained from Tibetan kefir had anti-inflammatory and angiogenic activity.Oct 31, 2016

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Pubmed Data : Microvasc Res. 2016 Nov ;108:29-33. Epub 2016 Jul 11. PMID: 27418582

Article Published Date : Oct 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Kefir

Diseases : Inflammation

Pharmacological Actions : Anti-Angiogenic, Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

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A review of nondairy kefir products: their characteristics and potential human health benefits.Nov 04, 2020

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Pubmed Data : Crit Rev Food Sci Nutr. 2020 Nov 5:1-17. Epub 2020 Nov 5. PMID: 33153292

Article Published Date : Nov 04, 2020

Study Type : Review

Additional Links

Substances : Kefir

Diseases : Hypercholesterolemia, Hyperglycemia

Pharmacological Actions : Anticholesteremic Agents, Gastrointestinal Agents, Hypoglycemic Agents

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Kefir may have potential to be an effective treatment for erythroleukemia.Dec 31, 2015

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Pubmed Data : Med Oncol. 2016 Jan ;33(1):7. Epub 2015 Dec 26. PMID: 26708130

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Kefir, Probiotics

Diseases : Acute Myeloid Leukemia

Pharmacological Actions : Antiproliferative , Apoptotic

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Kefir-based antimicrobials are being proposed as promising natural biopreservatives.Jun 03, 2020

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Pubmed Data : Int J Oncol. 2014 Mar ;44(3):830-7. Epub 2014 Jan 15. PMID: 24430613

Article Published Date : Feb 28, 2014

Study Type : In Vitro Study

Additional Links

Substances : Fermented Foods and Beverages, Kefir

Diseases : Acute Myeloid Leukemia, Cancers: Drug Resistant, Cancers: Multi-Drug Resistant

Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation

Additional Keywords : Dose Response

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L. paracasei CT12 appears to possess a potential probiotic value. May 04, 2020

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Pubmed Data : Curr Microbiol. 2020 May 5. Epub 2020 May 5. PMID: 32372103

Article Published Date : May 04, 2020

Study Type : In Vitro Study

Additional Links

Substances : Kefir, Lactobacillus paracasei, Probiotics

Pharmacological Actions : Gastrointestinal Agents

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Mechanisms of action of kefir in chronic cardiovascular and metabolic diseases.Dec 31, 2017

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Pubmed Data : Oncol Rep. 2015 Oct ;34(4):1659-66. Epub 2015 Aug 6. PMID: 26251956

Article Published Date : Sep 30, 2015

Study Type : In Vitro Study

Additional Links

Substances : Kefir

Diseases : Breast Cancer, Gastric Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation

Additional Keywords : Selective Cytotoxicity

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The emerging scenario of the gut-brain axis: the therapeutic actions of the new actor kefir against neurodegenerative diseases.Nov 19, 2021

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Kefir is a Sub of the following Topics

View the Evidence: 116 Abstracts with Kefir Research

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Kefir has a beneficial effect in decreasing insulin resistance.Dec 31, 2022

Bioactive compounds from kefir and their potential benefits on health.Dec 31, 2020

Effect of kefir beverage consumption on glycemic control.Jul 31, 2021

consuming kefir daily could prevent constipation.Jun 30, 2018

Consumption of kefir made with traditional microorganisms resulted in greater improvements in LDL cholesterol and plasma markers of inflammation.May 23, 2023

Consumption of probiotic-fermented milk (kefir) in diabetic patients in comparison with conventional fermented milk decreased the fasting blood glucose and HbA1C levels.Jan 31, 2015

Effect of administering kefir on the changes in fecal microbiota and symptoms of inflammatory bowel diseaseJan 20, 2019

Effects of kefir consumption on gut microbiota and health outcomes in women with polycystic ovary syndrome.Jul 31, 2024

Effects of kefir or milk supplementation on zonulin in overweight subjects.Apr 30, 2020

Homemade kefir consumption improves skin condition.Nov 12, 2021

Kefir drink causes a significant improvement in serum lipid profile.Jan 31, 2017

Kefir has positive effects on sleep disturbances, depression, and quality of life in postmenopausal women.Dec 31, 2018

Kefir improves cognitive deficits.Dec 31, 2019

Kefir is a viable exercise recovery beverage for cancer survivors enrolled in a structured exercise program.Sep 30, 2021

Kefir supplementation had favorable effects on some metabolic syndrome parameters.Sep 03, 2019

The effect of kefir supplementation on improving human endurance exercise performance and antifatigue.Feb 24, 2021

The effects of postexercise consumption of a kefir beverage on performance and recovery during intensive endurance training.Oct 31, 2015

Benefits of multi-day supplementation with probiotic kefir in Rasmussen encephalitis.Aug 29, 2021

Ameliorative effect of kefir against γ-irradiation induced liver injury in male rats: impact on oxidative stress and inflammation.Jun 24, 2020

A novel kefir product (PFT) inhibits Ehrlich ascites carcinoma in mice via induction of apoptosis and immunomodulation.Apr 27, 2020

A soluble non-bacterial fraction of kefir had beneficial on blood pressure and cardiac hypertrophy in hypertensive rats.Jul 31, 2018

AB-kefir reduced body weight and ameliorated inflammation in adipose tissue of obese mice fed a high-fat diet.Jun 23, 2021

Administration of kefir in myocardial infarction induced by isoproterenol can protect the heart and minimize the toxic damage.Mar 31, 2018

Anti-diabetic effect of Lactobacillus paracasei isolated from Malaysian water kefir grains.Sep 26, 2023

Antiobesity effect of exopolysaccharides isolated from kefir grains.Nov 21, 2017

Antiobesity effect of prebiotic polyphenol-rich grape seed flour supplemented with probiotic kefir-derived lactic acid bacteria.Nov 27, 2018

Chronic administration of the soluble, nonbacterial fraction of kefir attenuates lipid deposition.Feb 28, 2017

Dietary high-fructose reduces barrier proteins and activates mitogenic signalling in the testis.Dec 05, 2021

Dose-dependent effects of kefir on colitis induced by trinitrobenzene sulfonic acid in rats.Aug 31, 2019

Effects of kefir fermented milk beverage on sodium dextran sulfate (DSS)-induced colitis.Dec 31, 2022

Effects of kefir on ischemia-reperfusion injury.Dec 31, 2014

Evaluation of the role of kefir in management of non-alcoholic steatohepatitis.Jan 04, 2023

Gastroprotective effect of kefir on ulcer induced in irradiated rats.Feb 28, 2015

Gastroprotective effect of oral kefir on indomethacin-induced acute gastric lesions.Sep 14, 2018

Kefir alleviates obesity and hepatic steatosis in high-fat diet-fed mice by modulation of gut microbiota and mycobiota.Dec 31, 2016

Kefir ameliorates alcohol-induced liver injury through modulating gut microbiota and fecal bile acid profile.Nov 06, 2023

Kefir ameliorates hypertension via gut-brain mechanisms in spontaneously hypertensive rats.Dec 11, 2019

Kefir can signal through the microbiota-gut-immune-brain axis and modulate host behaviour.May 17, 2020

Kefir contains a carbohydrate fraction with anti-inflammatory and cicatrizing (healing via scar formation) activity. Jun 01, 2008

Kefir has a protective effect against bone loss, deterioration of trabecular microarchitecture, and biomechanical dysfunction.Jan 31, 2015

Kefir has antitumor activity in an animal model of breast cancer. Apr 01, 2007

Kefir has the potential to benefit the management of MetS.Jul 06, 2016

Kefir is a natural product able to protect against the hepatotoxic effects of deltamethrine.May 31, 2019

Kefir may reduce diarrhea for those treated for Clostridium difficile with antibiotics. Jul 01, 2009

Kefir mitigates renal damage caused by zearalenone in female wistar rats by reducing oxidative stress.May 27, 2024

Kefir modulates gut microbiota and reduces DMH-associated colorectal cancer.Jan 31, 2022

Kefir peptides alleviate high-fat diet-induced atherosclerosis.May 28, 2020

Kefir peptides alleviate particulate matter-induced pulmonary inflammation.Aug 07, 2019

Kefir peptides attenuate atherosclerotic vascular calcification and osteoporosis.Dec 31, 2022

Kefir peptides can improve the symptoms of NAFLD.Dec 11, 2016

Kefir peptides mitigate bleomycin-induced pulmonary fibrosis in mice through modulating oxidative stress, inflammation and gut microbiota.Apr 30, 2024

Kefir peptides prevent hyperlipidemia and obesity in high-fat-diet-induced obesity. Dec 31, 2017

Kefir pretreatment in spinal cord ischemia/reperfusion reduced oxidative stress and neuronal degeneration as a neuroprotective agent.Apr 30, 2015

Kefir prevented excess fat accumulation in diet-induced obese mice.Apr 30, 2017

Kefir protective effects against nicotine cessation-induced anxiety and cognition impairments.Dec 31, 2013

Kefir recovered depressive-like behaviour in CantonS lineage of Drosophila melanogaster exposed to chronic unpredictable mild stress protocol.Sep 09, 2024

Kefir supplementation can alter the gut microbiota composition, improve performance, and combat physical fatigue.Jul 03, 2018

Kefir supplementation might prove a viable strategy in improving quality of life in ASD subjects.Jul 08, 2021

Kefir treatment ameliorates dextran sulfate sodium-induced colitis in rats.Dec 13, 2015

Kefir-derived Lactobacillus extracellular vesicles can be potentially used for developing innovative strategies for alleviating inflammatory bowel disease.Sep 30, 2018

Kefir-fermented peptides prevent menopausal osteoporosis and mildly modulate the structure of the gut microbiota.Nov 08, 2020

L. diolivorans 1Z showed to be a potential probiotic strain that protected mice from death after challenge with S. Typhimurium.Dec 31, 2017

Lactate exerted a protective effect against Salmonella in a mouse model.Jul 31, 2017

Lactobacillus mali ameliorated hepatic steatosis by modulating lipid metabolism and antioxidant activity.Dec 31, 2017

Milk and kefir maintain aspects of health during doxorubicin treatment in rats.Jan 15, 2019

Milk kefir alters fecal microbiota impacting gut and brain health.Jul 31, 2023

Milk Kefir therapy reduces inflammation and alveolar bone loss on periodontitis in rats.Jun 30, 2021

Novel kefir exopolysaccharides mitigate lipopolysaccharide-induced systemic inflammation.Sep 04, 2023

Osteoprotective effects of kefir fortified with omega-3 and vitamin C.Jun 23, 2021

Potential anti-tumor activity of kefir-induced juglone and resveratrol fractions against ehrlich ascites carcinoma.Dec 31, 2019

Prevention of DSS-induced colitis in mice with water kefir microbiota.Jul 30, 2023

Probiotic kefir was able to attenuate the molecular, structural, and physiological cardiovascular changes induced by BPA.Oct 24, 2019

Kefir

View the Evidence:
116 Abstracts with Kefir Research