Lactobacillus casei

Name	AC	CK
C-Reactive Protein	5	50
Constipation	4	40
Obesity	6	36
Inflammation	5	34
Diabetes Mellitus: Type 2	4	32
Rheumatoid Arthritis	4	32
Irritable Bowel Syndrome	3	22
Oxidative Stress	3	22
Diarrhea	2	20
Diarrhea: Antibiotic-Associated	2	20
Diverticular Disease	2	20
Upper Respiratory Infections	2	20
Aflatoxicosis	2	12
Aging	2	12
Liver Cancer	2	12
Pneumonia	2	12
Alcoholic Liver Disease	1	10
Allergic Rhinitis	1	10
Antibiotic Toxicity	1	10
Anxiety Disorders	1	10
Bacteremia	1	10
Biliary Obstruction	1	10
Biliary Tract Diseases	1	10
Breast Milk: Inadequate/Poor Quality	1	10
Clostridium Infections	1	10
Coronary Artery Disease	1	10
Depressive Disorder	1	10
Diabetic Complications	1	10
Diarrhea: in Children	1	10
Diverticulitis	1	10
Diverticulosis	1	10
Fractures: Bone	1	10
Gastroenteritis	1	10
Gestational Diabetes	1	10
Gingivitis	1	10
Hemodialysis	1	10
Hemorrhoids	1	10
Hyperoxaluria	1	10
Infant Infections	1	10
Insulin Resistance	1	10
Kidney Stones	1	10
Lactation Disorders	1	10
Multiple Sclerosis	1	10
Organ Transplantation: Liver	1	10
Osteoarthritis: Knee	1	10
Oxaluria	1	10
Pneumonia: Ventilator-associated	1	10
Prediabetes	1	10
Sleep Disorders	1	10
Stress	1	10
Surgical Complications: Infection	1	10
Systemic Inflammatory Response Syndrome	1	10
Breast Cancer	3	6
Colon Cancer	3	5
Colorectal Cancer	3	5
Cancer Metastasis	2	4
Chemically-Induced Liver Damage	2	4
Colitis	2	4
Hyperlipidemia	2	4
Escherichia coli Infections	2	3
Arthritis	1	2
Aspirin-Induced Toxicity	1	2
Bisphenol-A Toxicity	1	2
Breast Cancer: Lung Metastasis	1	2
Chemotherapy-Induced Toxicity: 5-fluorouracil	1	2
Cognitive Decline/Dysfunction	1	2
Dermatitis	1	2
Ductal Carcinoma: Invasive	1	2
Dysbiosis	1	2
Dyslipidemias	1	2
Endotoxemia	1	2
Fructose-Induced Toxicity	1	2
Giardiasis	1	2
High Fat Diet	1	2
Hyperglycemia	1	2
Hyperinsulinism	1	2
Immune Disorders: Low Immune Function	1	2
Lipopolysaccharide-Induced Toxicity	1	2
Listeria Infections	1	2
Liver Damage: Aflatoxin-Induced	1	2
Liver Stress: Fructose-Induced	1	2
Low Immune Function: Natural Killer Cells	1	2
Mucositis	1	2
Nonalcoholic fatty liver disease (NAFLD)	1	2
Osteoarthritis	1	2
Pesticide Toxicity	1	2
Pneumococcal Infections	1	2
Sepsis	1	2
Toxoplasmosis	1	2
Cervical Cancer	1	1
DNA damage	1	1
Gastric Cancer	1	1
Gastrointestinal Inflammation	1	1
Heterocyclic Aromatic Amine Induced Toxicity	1	1
Influenza A	1	1
Leukemia: Chronic myelogenous leukemia (CML)	1	1
MRSA	1	1
Malabsorption Syndrome	1	1
Urinary Tract Infections	1	1
Bladder Cancer	1	0

Name	AC	CK
Anti-Inflammatory Agents	15	102
Gastrointestinal Agents	15	93
Antioxidants	8	38
Immunomodulatory	11	37
Tumor Necrosis Factor (TNF) Alpha Inhibitor	6	36
Hypolipidemic	5	26
Hypoglycemic Agents	3	22
Antidiarrheals	2	20
Hepatoprotective	4	16
Interleukin-6 Downregulation	4	16
Anti-Bacterial Agents	4	14
Anticholesteremic Agents	2	12
Malondialdehyde Down-regulation	2	12
Antidepressive Agents	1	10
Insulin Sensitizers	1	10
Interleukin-10 upregulation	1	10
Interleukin-8 downregulation	1	10
Antiproliferative	5	7
Apoptotic	6	7
Chemopreventive	3	6
Detoxifier	3	5
Anticarcinogenic Agents	2	4
Interleukin-17 downregulation	2	4
Anti-metastatic	1	2
Antigiardial agents	1	2
Antiparasitic Agents	1	2
Chemoprotective Agents	1	2
Gastroprotective	2	2
Immunostimulatory	1	2
Interleukin-12 downregulation	1	2
Interleukin-2 Downregulation	1	2
Matrix Metalloproteinases Inhibitors	1	2
Osteoprotective	1	2
Prophylactic Agents	1	2
Renoprotective	1	2
Antineoplastic Agents	1	1
Antiviral Agents	1	1
Genoprotective	1	1

[+]

Lactobacillus casei rhamnosus is effective in children with chronic constipation.Aug 01, 2007

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Pubmed Data : Pediatr Int.2007 Aug;49(4):485-90 PMID: 17587273

Article Published Date : Aug 01, 2007

Study Type : Human Study

Additional Links

Substances : Lactobacillus casei

Diseases : Constipation

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A fermented milk drink containing Lactobacillus casei Shirota could reduce serum aflatoxin B1-lysine adduct concentrations.Jan 13, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Br J Nutr. 2016 Jan 14 ;115(1):39-54. Epub 2015 Oct 22. PMID: 26490018

Article Published Date : Jan 13, 2016

Study Type : Human Study

Additional Links

Substances : Fermented Foods and Beverages, Lactobacillus casei, Milk: Fermented

Diseases : Aflatoxicosis

Pharmacological Actions : Gastrointestinal Agents

Problem Substances : Aflatoxin

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A probiotic containing L. acidophilus and L. casei reduces the risk of antibiotic-associated diarrhea in adults patients.Jul 01, 2010

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Pubmed Data : Am J Gastroenterol. 2010 Jul;105(7):1636-41. Epub 2010 Feb 9. PMID: 20145608

Article Published Date : Jul 01, 2010

Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective, Hypolipidemic

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Effects of probiotic supplementation on metabolic status in pregnant women.Sep 30, 2016

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Pubmed Data : Arch Iran Med. 2016 Oct ;19(10):687-682. PMID: 27743432

Article Published Date : Sep 30, 2016

Study Type : Human Study

Additional Links

Substances : Bifidobacterium Bifidum, Lactobacillus Acidophilus, Lactobacillus casei

Diseases : C-Reactive Protein, Insulin Resistance, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

Fermented milk might alleviate constipation-related symptoms, provide satisfactory bowel habit and result in earlier recovery from haemorrhoids in women during puerperium.Dec 31, 2014

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Pubmed Data : Benef Microbes. 2015 Jan 1 ;6(3):253-62. PMID: 25380801

Article Published Date : Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2021 Oct 29 ;13(11). Epub 2021 Oct 29. PMID: 34836153

Article Published Date : Oct 28, 2021

Study Type : Human Study

Additional Links

Substances : Lactobacillus casei

Diseases : Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation

[+]

Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R and Lactobacillus rhamnosus CLR2 improve quality-of-life and IBS symptoms.Sep 17, 2018

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Pubmed Data : Benef Microbes. 2018 Sep 18 ;9(5):697-706. Epub 2018 Jun 11. PMID: 29888656

Article Publish Status : This is a free article. Click here to read the complete article.

Probiotic drinks containing Lactobacillus casei DN-114001 reduce antibiotic-associated diarrhea.Nov 13, 2014

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The effects of the Lactobacillus casei strain on obesity in children.Aug 23, 2017

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Pubmed Data : Benef Microbes. 2017 Aug 24 ;8(4):535-543. Epub 2017 Jun 16. PMID: 28618860

Article Published Date : Aug 23, 2017

Study Type : Human Study

Additional Links

Substances : Lactobacillus casei: Shirota

Diseases : Obesity

Additional Keywords : Anti-Obesity Agents

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The long-term consumption of LcS-fermented milk may be useful for decreasing the daily risk of infection and improving the quality of life.Dec 31, 2015

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Pubmed Data : Ann Nutr Metab. 2016 ;68(1):51-9. Epub 2015 Nov 25. PMID: 26599038

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Comput Struct Biotechnol J. 2021 ;19:5888-5897. Epub 2021 Oct 22. PMID: 34815833

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Lactobacillus casei

Diseases : Antibiotic Toxicity

Pharmacological Actions : Gastrointestinal Agents, Gastroprotective

Problem Substances : Antibiotics

[+]

dietary L. casei alleviates LPS-induced liver injury via reducing pro-inflammatory cytokines and increasing anti-oxidative capacity.Nov 25, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Additional Keywords : Natural Substance/Drug Synergy

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Lactobacillus casei LC2W can inhibit the colonization of Escherichia coli O157:H7 in vivo and reduce the severity of colitis.Aug 31, 2019

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Pubmed Data : Food Funct. 2019 Sep 1 ;10(9):5843-5852. Epub 2019 Aug 29. PMID: 31464316

Article Published Date : Aug 31, 2019

Study Type : Animal Study

Additional Links

Substances : Lactobacillus casei

Diseases : Colitis, Escherichia coli Infections

Pharmacological Actions : Anti-Bacterial Agents

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Lactobacillus casei LC89 exerts antidiabetic effects through regulating hepatic glucagon response and gut microbiota in type 2 diabetic mice.Sep 19, 2021

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Pubmed Data : Food Funct. 2021 Sep 20 ;12(18):8288-8299. Epub 2021 Sep 20. PMID: 34308462

Article Published Date : Sep 19, 2021

Study Type : Animal Study

Additional Links

Substances : Lactobacillus casei

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Gastrointestinal Agents, Hypoglycemic Agents

Additional Keywords : Gene Expression Regulation

[+]

Lactobacillus casei modulates gut cells to inhibit the colonization and multiplication of Giardia trophozoites.Jan 31, 2011

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Pubmed Data : Can J Microbiol. 2011 Feb ;57(2):127-35. PMID: 21326354

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Pubmed Data : J Food Sci. 2019 Nov 24. Epub 2019 Nov 24. PMID: 31762034

Article Published Date : Nov 23, 2019

Study Type : Animal Study

Additional Links

Substances : Lactobacillus casei, Probiotics

Diseases : Hyperlipidemia

Pharmacological Actions : Hypolipidemic

[+]

Lactobacilluscasei Zhang administration exert both preventive and ameliorative effect on oral glucose tolerance.Jan 31, 2014

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Pubmed Data : Eur J Nutr. 2014 Feb ;53(1):221-32. PMID: 23797890

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Pubmed Data : J Environ Sci Health B. 2016 Feb 6:1-10. Epub 2016 Feb 6. PMID: 26852781

Article Published Date : Feb 05, 2016

Study Type : Environmental, Plant Study

Additional Links

Substances : Lactobacillus casei

Diseases : Pesticide Toxicity

Pharmacological Actions : Detoxifier

Problem Substances : Chlorpyrifos

[+]

Treatment with Lactobacillus casei modulates immune responses and significantly protects mice against DMH-induced colorectal cancer.Jan 08, 2016

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Pubmed Data : J Gastroenterol. 2016 Jan 9. Epub 2016 Jan 9. PMID: 26749362

Article Published Date : Jan 08, 2016

Study Type : Animal Study

Additional Links

Substances : Lactobacillus casei, Probiotics

Diseases : Colorectal Cancer

Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive, Immunomodulatory

[+]

Ability of probiotic Lactobacillus casei DN 114001 to bind or/and metabolise heterocyclic aromatic amines in vitro.Sep 30, 2009

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Microbiol Res. 2010 Oct 20 ;165(8):674-86. Epub 2010 Jan 29. PMID: 20116228

Article Published Date : Oct 20, 2010

Study Type : In Vitro Study

Additional Links

Substances : Lactobacillus Acidophilus, Lactobacillus casei

Diseases : MRSA

Pharmacological Actions : Anti-Bacterial Agents

[+]

Lactobacillus casei ATCC 393 alleviates Enterotoxigenic Escherichia coli K88-induced intestinal barrier dysfunction.Jan 07, 2020

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Pubmed Data : Life Sci. 2020 Jan 8:117281. Epub 2020 Jan 8. PMID: 31926249

The study of extracellular protein fractions of probiotic candidate bacteria on cancerous cell line.Oct 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Arch Iran Med. 2016 Nov ;19(11):779-785. PMID: 27845547

Article Published Date : Oct 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Lactobacillus casei

Diseases : Leukemia: Chronic myelogenous leukemia (CML)

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Lactobacillus casei may contribute to reduction in recurrence of bladder cancer.Feb 01, 2008

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Pubmed Data : J Urol. 2008 Feb;179(2):485-90. PMID: 18076918

Article Published Date : Feb 01, 2008

Additional Links

Substances : Lactobacillus casei

Diseases : Bladder Cancer

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View the Evidence: 123 Abstracts with Lactobacillus casei Research

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Lactobacillus casei rhamnosus is effective in children with chronic constipation.Aug 01, 2007

A fermented milk drink containing Lactobacillus casei Shirota could reduce serum aflatoxin B1-lysine adduct concentrations.Jan 13, 2016

A probiotic containing L. acidophilus and L. casei reduces the risk of antibiotic-associated diarrhea in adults patients.Jul 01, 2010

A probiotic mixture has positive effects on symptoms of constipation in children. Jan 01, 2007

A synbiotic combination reduces infectitious complications in patients after elective living donor liver transplantation. Jul 07, 2010

Administration of probiotics could greatly accelerating the healing process.Sep 15, 2016

Beneficial effects of Lactobacillus casei strain Shirota on academic stress-induced sleep disturbance in healthy adults.Apr 25, 2017

Both mesalazine and Lactobacillus casei seem to be effective in preventing recurrence of symptomatic uncomplicated diverticular disease of the colonApr 01, 2006

Consumption of a fermented dairy product containing the probiotic Lactobacillus casei reduces the duration of respiratory infections in the elderly. Jan 01, 2010

Consumption of probiotic-fermented milk (kefir) in diabetic patients in comparison with conventional fermented milk decreased the fasting blood glucose and HbA1C levels.Jan 31, 2015

Daily intake of fermented milk with Lactobacillus casei strain Shirota reduces the incidence and duration of upper respiratory tract infections.Jan 31, 2017

Effect of fermented soymilk-honey from different probiotics on osteocalcin level in menopausal women.Oct 12, 2021

Effect of Lactobacillus casei on lipid metabolism and intestinal microflora in patients with alcoholic liver injury.Jan 28, 2021

Effects of probiotic supplementation on metabolic status in pregnant women.Sep 30, 2016

Fermented milk might alleviate constipation-related symptoms, provide satisfactory bowel habit and result in earlier recovery from haemorrhoids in women during puerperium.Dec 31, 2014

Fermented soymilk beneficially modifies the gut microbiota in premenopausal healthy women.Feb 26, 2018

Immune response of healthy adults to the ingested probiotic Lactobacillus casei Shirota.Nov 30, 2016

L. casei LTL 1879 can significantly improve specific immune, oxidative, and gut microbiota characteristics related to health factors.Oct 28, 2021

Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R and Lactobacillus rhamnosus CLR2 improve quality-of-life and IBS symptoms.Sep 17, 2018

Lactobacillus casei and Bifidobacterium breve reduce urinary oxalate excretion in nephrolithiasis patients.Apr 01, 2009

Lactobacillus casei could reduce the incidence of ventilator associated pneumonia and colonization with resistant bacteria in oropharyngeal cavity.Feb 28, 2015

Lactobacillus casei has a beneficial effect on intestinal fermentation patterns in patients with irritable bowel syndrome.Aug 28, 2008

Lactobacillus casei is effective for managing childhood diarrhea.May 22, 2019

Lactobacillus casei modulates immune response in allergic rhinitis and may help to alleviate symptoms.Aug 01, 2008

Lactobacillus casei modulates inflammatory cytokines and metabolites during tuberculosis treatmentFeb 28, 2022

Lactobacillus casei Shirota consumption could serve as a novel therapeutic option in the clinical management of knee osteoarthritis.Oct 12, 2017

Lactobacillus casei strain shirota alleviates constipation in adults. Dec 31, 2018

Lactobacillus casei strain Shirota may prevent hypersecretion of cortisol and physical symptoms under stressful conditions.Feb 19, 2016

Lactobacillus is superior to Mesalazine in the long-term remission of symptomatic uncomplicated diverticular disease of the colon. May 01, 2008

Multi-Strain Probiotic (UB0316) is effective in reducing BMI, body weight and WHR in overweight/obese adults.Dec 08, 2019

Perioperative probiotic treatment prevents postoperative infectious complications in biliary cancer surgery.Nov 01, 2006

Probiotic administration in patients with major depressive disorder for 8 weeks had beneficial effects on beck depression Inventory.Sep 27, 2015

Probiotic assisted weight management as a main factor for glycemic control in patients with type 2 diabetesDec 31, 2018

Probiotic drinks containing Lactobacillus casei DN-114001 reduce antibiotic-associated diarrhea.Nov 13, 2014

Probiotic supplementation for 12 weeks in patients with multiple sclerosis significantly improved gene expression of IL-8 and TNF-α.Oct 31, 2017

Probiotic supplementation improves inflammatory status in patients with rheumatoid arthritis.Mar 31, 2014

Probiotic supplementation in diabetic hemodialysis patients has beneficial metabolic effects.Dec 31, 2016

Probiotic supplementation may be an adjunct therapy for rheumatoid arthritis patients and help alleviate symptoms and improve inflammatory cytokines.May 31, 2014

Probiotics affect the clinical inflammatory parameters of experimental gingivitis in humans.Jun 30, 2011

Synbiotic supplementation in diabetic patients with coronary heart disease had beneficial effects on insulin metabolism and HDL-cholesterol levels.Dec 31, 2016

The consumption of fermented milk with Lactobacillus casei in lactating mothers has a positive effect on the mother and offspring's immunological status.Oct 01, 2008

The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes.Apr 30, 2018

The effects of the Lactobacillus casei strain on obesity in children.Aug 23, 2017

The long-term consumption of LcS-fermented milk may be useful for decreasing the daily risk of infection and improving the quality of life.Dec 31, 2015

The probiotics Bifidobacterium breve and Lactobacillus casei reduce complications in patients with SIRS. May 01, 2009

The results of this study indicated that taking probiotic supplements for 8 weeks among patients with rheumatoid arthritis had beneficial effects.Aug 31, 2016

These findings suggest that Lactobacillus casei strain Shirota may favourably affect metabolic abnormalities in obese prediabetic subjects.Dec 31, 2017

Lactobacillus casei could act as a potent nutraceutical modulator forosteoarthritis treatment by reducing pain, inflammatory responses, and articular cartilage degradation.Dec 16, 2010

Administration of probiotics to obese hosts improved the gut microbiota and the mucosal immunity altered by obesity.Oct 31, 2014

Antidiabetic effects of Lactobacillus casei fermented yogurt through reshaping gut microbiota structure in type 2 diabetes.Nov 15, 2018

Antiparasitic action of Lactobacillus casei ATCC 393 and Lactobacillus paracasei CNCM strains in CD-1 mice experimentally infected with Trichinella britovi.Feb 24, 2022

Apple pectin and Lactobacillus casei inhibit liver cancer metastasis. Dec 01, 1999

Bifidobacterium and Lactobacillus improve inflammatory bowel disease.Jun 30, 2023

Combined immunotherapy with heated 4T1 cells and heated Lactobacillus casei promoted beneficial outcomes in our mouse model of breast cancer.Aug 31, 2017

Daily L. casei Zhang supplementation could alleviate the side effect of cefdinir intervention and facilitate the restoration of gut microbial homeostasis.Dec 31, 2020

dietary L. casei alleviates LPS-induced liver injury via reducing pro-inflammatory cytokines and increasing anti-oxidative capacity.Nov 25, 2017

Fermented milk administration to mice decreased or suppressed tumor growth, with less tumor vascularity, extravasation of tumor cells, and lung metastasis.May 31, 2015

Fermented onion has a preventive and therapeutic effect on hyperlipidemic disease.Dec 31, 2018

Gut Microbiota Profiling of Aflatoxin B1-Induced Rats Treated with Lactobacillus casei ShirotaJan 16, 2019

Immune modulation effects of Lactobacillus casei variety rhamnosus on enterocytes and intestinal stem cells in a 5-FU-induced mucositis.Dec 31, 2020

Immunobiotic and paraprobiotic potential effect of Lactobacillus casei in a systemic toxoplasmosis murine model.Jan 13, 2020

L. casei (ATCC334), was able to significantly suppress the induction of adjuvant-induced arthritis and protect bones from destruction.Jan 16, 2019

L. casei and B. bifidum alone and in combination ameliorated hyperglycemia, dyslipidemia, and oxidative stress in STZ-induced diabetic Wistar rats.Dec 31, 2015

Lacticaseibacillus casei AMBR2 restores airway epithelial integrity in chronic rhinosinusitis.Jun 30, 2021

Lactobaccilus casei Shirota protects from fructose-induced fatty liver in an animal model. Jun 26, 2012

Lactobacillus and Bifidobacterium improved physiological function and cognitive ability in aged mice by the regulation of gut microbiota.Aug 20, 2019

Lactobacillus casei ameliorates the adverse effects of experimental liver inury. Jun 01, 2009

Lactobacillus casei and its supplement alleviate stress-induced depression and anxiety.May 25, 2023

Lactobacillus casei ATCC 393 and it's metabolites alleviate dextran sulphate sodium-induced ulcerative colitis.Nov 28, 2021

Lactobacillus casei beneficially modulates immuno-coagulative response in an endotoxemia model.Nov 26, 2017

Lactobacillus casei CCFM1074 alleviates collagen-induced arthritis.Dec 31, 2020

Lactobacillus casei CCFM419 attenuates type 2 diabetes via a gut microbiota dependent mechanism.Sep 19, 2017

Lactobacillus casei

View the Evidence:
123 Abstracts with Lactobacillus casei Research