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21 Diseases Researched for Lettuce
NameACCKFocus
Inflammation313Locked
Colorectal Cancer312Locked
Colon Cancer211Locked
Gingivitis110Locked
Insomnia110Locked
Periodontal Diseases110Locked
DNA damage34Locked
Cardiovascular Diseases12Locked
Depression12Locked
Diabetes Mellitus: Type 212Locked
Mercury Poisoning12Locked
Oxidative Stress22Locked
Sleep Disorders12Locked
Arteriosclerosis11Locked
Chemotherapy-Induced Toxicity: Cisplatin11Locked
Gram-Negative Bacterial Infections11Locked
Gram-Positive Bacterial Infections11Locked
Lipid Peroxidation11Locked
Liver Cancer11Locked
Lung Cancer11Locked
Testicular Injury: Chemical/Metal Induced11Locked
16 Pharmacological Actions Researched for Lettuce
NameACCKFocus
Anti-Inflammatory Agents414Locked
Chemopreventive110Locked
Hypnotics and Sedatives110Locked
Antioxidants89Locked
Neuroprotective Agents23Locked
Analgesics12Locked
Anticoagulants12Locked
Antidepressive Agents12Locked
Hypoglycemic Agents12Locked
Antimicrobial11Locked
Antiproliferative 11Locked
Apoptotic11Locked
Cell cycle arrest11Locked
Chemoprotective Agents11Locked
Cytotoxic11Locked
Genoprotective11Locked
Related Topics

Lettuce is a Sub of the following Topic

View the Evidence:
25 Abstracts with Lettuce Research

[+]

Dietary nitrate consumption may be a useful adjunct in the control of chronic gingivitis.Jun 30, 2016

Pubmed Data : J Clin Periodontol. 2016 Jul ;43(7):603-8. Epub 2016 May 10. PMID: 26969836
Article Published Date : Jun 30, 2016
Study Type : Human Study
Additional Links
Substances : Lettuce
Diseases : Gingivitis, Inflammation, Periodontal Diseases
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Dietary Nitrate Consumption
[+]

Lettuce seed decreased insomnia during pregnancy and could be recommended as a safe natural remedy for treatment of pregnancy-related insomnia.Dec 04, 2018

Pubmed Data : J Ethnopharmacol. 2018 Dec 5 ;227:176-180. Epub 2018 Aug 30. PMID: 30172900
Article Published Date : Dec 04, 2018
Study Type : Human Study
Additional Links
Substances : Lettuce
Diseases : Insomnia
Pharmacological Actions : Hypnotics and Sedatives
Additional Keywords : Phytotherapy
[+]

Total vegetable intake, total fruit intake, and lettuce, apple, and banana consumption is associated with a reduced risk for colorectal cancer.Jan 01, 1996

Pubmed Data : Nutr Cancer. 1996;25(3):297-304. PMID: 8771572
Article Published Date : Jan 01, 1996
Study Type : Human Study
Additional Links
Substances : Apples, Banana, Fruit: All, Lettuce, Vegetables: All
Diseases : Colon Cancer, Colorectal Cancer
Pharmacological Actions : Chemopreventive
[+]

A lettuce and skullcap mixture can be used as an herbal agent for sleep disorders.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2018 ;41(8):1269-1276. PMID: 30068876
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Lettuce, Skullcap: Chinese
Diseases : Sleep Disorders
Additional Keywords : Plant Extracts
[+]

Arbuscular mycorrhizal could improve drought tolerance in lettuce and tomato plants. Aug 24, 2015

Pubmed Data : Plant Cell Environ. 2015 Aug 25. Epub 2015 Aug 25. PMID: 26305264
Article Published Date : Aug 24, 2015
Study Type : Environmental
Additional Links
Substances : Lettuce, Tomato
Additional Keywords : Arbuscular Mycorrhizal Fungi
[+]

Feeding mice fed a high-fat/high-cholesterol diet lettuce resulted in an improvement of plasma cholesterol and lipid levels, prevention of lipid peroxidation and an increase of the antioxidant defence system. Apr 01, 2009

Pubmed Data : Br J Nutr. 2009 Apr;101(8):1246-54. Epub 2009 Feb 25. PMID: 19243638
Article Published Date : Apr 01, 2009
Study Type : Animal Study
Additional Links
Substances : Lettuce
Diseases : Cardiovascular Diseases, DNA damage
Pharmacological Actions : Antioxidants
[+]

Fermented lettuce extract containing nitric oxide metabolites attenuates inflammatory parameters.Feb 22, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Feb 23 ;15(5). Epub 2023 Feb 23. PMID: 36904105
Article Published Date : Feb 22, 2023
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Lettuce
Diseases : Arthritis, Rheumatoid Arthritis
Pharmacological Actions : Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Plant Extracts
[+]

L. sativa can potentially act as a strong herbal drug due to its multiple pharmaceutical effects and is therefore of interest in drug discovery and development of formulations.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2015 ;15:199. Epub 2015 Jun 27. PMID: 26115918
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Lettuce
Diseases : Depression, Inflammation
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Anticoagulants, Antidepressive Agents
Additional Keywords : Natural Substances Versus Drugs
[+]

Lactuca scariola leaves could be a substitute for synthetic drugs to treat diabetic patients.Aug 25, 2015

Pubmed Data : J Basic Clin Physiol Pharmacol. 2015 Aug 26. Epub 2015 Aug 26. PMID: 26352090
Article Published Date : Aug 25, 2015
Study Type : Animal Study
Additional Links
Substances : Lettuce
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
[+]

Launaea taraxacifolia mitigated mercuric chloride alteration of the microanatomy of rat brain.Nov 01, 2017

Pubmed Data : J Diet Suppl. 2017 Nov 2 ;14(6):613-625. Epub 2017 Mar 1. PMID: 28471730
Article Published Date : Nov 01, 2017
Study Type : Animal Study
Additional Links
Substances : Lettuce
Diseases : Mercury Poisoning
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
Problem Substances : Mercury
[+]

Spectral analysis and antiulcer potential of Lactuca sativa through the amelioration of proinflammatory cytokines and apoptosis markers.Oct 18, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Life (Basel). 2022 Oct 19 ;12(10). Epub 2022 Oct 19. PMID: 36295076
Article Published Date : Oct 18, 2022
Study Type : Animal Study
Additional Links
Substances : Lettuce
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Anti-Ulcer Agents, Gastroprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substances Versus Drugs
[+]

A phenolic extract of romaine lettuce protected PC-12 cells against oxidative stress.Jul 31, 2010

Pubmed Data : J Med Food. 2010 Aug ;13(4):779-84. PMID: 20553182
Article Published Date : Jul 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Lettuce
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

A water-soluble fraction of lettuce exerts protective effects against glucose/serum deprivation-induced DNA damage.Apr 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Pol Pharm. 2014 May-Jun;71(3):409-13. PMID: 25265820
Article Published Date : Apr 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Lettuce
Diseases : DNA damage, Lipid Peroxidation
Pharmacological Actions : Antioxidants, Genoprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Beneficial phytochemicals with anti-tumor potential revealed through metabolic profiling of new red pigmented lettuces.Apr 10, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 Apr 11 ;19(4). Epub 2018 Apr 11. PMID: 29641499
Article Published Date : Apr 10, 2018
Study Type : In Vitro Study
Additional Links
Substances : Lettuce
Diseases : Colon Cancer, Colorectal Cancer, Liver Cancer, Lung Cancer
Pharmacological Actions : Antioxidants, Cytotoxic
[+]

Iodine-biofortified lettuce regulates transcription of genes associated with cell cycle and apoptotic process leading to reduced Caco-2 cells proliferation.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(1):e0147336. Epub 2016 Jan 22. PMID: 26799209
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Iodine, Lettuce
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Gene Expression Regulation, Plant Extracts
[+]

Isolation and identification of antimicrobial substances from Korean Lettuce.May 31, 2018

Pubmed Data : Food Sci Biotechnol. 2018 Jun ;27(3):789-797. Epub 2018 Jan 16. PMID: 30263805
Article Published Date : May 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Lettuce
Diseases : Gram-Negative Bacterial Infections, Gram-Positive Bacterial Infections
Pharmacological Actions : Antimicrobial
[+]

L. taraxacifolia could be used as a natural antioxidant and also as a preventive therapy against diseases such as arteriosclerosis associated with DNA damage.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nat Sci Biol Med. 2018 Jan-Jun;9(1):6-13. PMID: 29456385
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lettuce
Diseases : Arteriosclerosis, DNA damage
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

L. taraxacifolia has protective potential against cisplatin damage.May 31, 2015

Pubmed Data : Andrologia. 2015 Jun ;47(5):553-9. Epub 2014 Jun 11. PMID: 24919929
Article Published Date : May 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Lettuce
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Chemoprotective Agents
Additional Keywords : Plant Extracts
[+]

Lettuce extract significantly decreased reactive oxygen species, nitric oxide release, inducible nitric oxide synthase and cycloxygenase-2 expression.Jan 14, 2015

Pubmed Data : Food Chem. 2015 Jan 15 ;167:153-61. Epub 2014 Jul 4. PMID: 25148972
Article Published Date : Jan 14, 2015
Study Type : In Vitro Study
Additional Links
Substances : Lettuce, Polyphenols
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Plant Extracts
[+]

Lettuce-avicularin treatment reverses insulin resistance through stimulation of glycolytic kinases and insulin signaling molecules.Jan 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2021 Feb ;24(2):232-239. PMID: 33953863
Article Published Date : Jan 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Lettuce
Diseases : Insulin Resistance
Pharmacological Actions : Insulin Sensitizers
[+]

Molecular effects of iodine-biofortified lettuce in human gastrointestinal cancer cells.Oct 13, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Oct 14 ;14(20). Epub 2022 Oct 14. PMID: 36296971
Article Published Date : Oct 13, 2022
Study Type : In Vitro Study
Additional Links
Substances : Iodine, Lettuce
Diseases : Colon Cancer, Gastric Cancer
Pharmacological Actions : Antioxidants, Antiproliferative , Apoptotic, Bcl-2 protein down-regulation
Additional Keywords : Epigenetic Modification In Cancer, Plant Extracts
[+]

Nutritional value of commercial and traditional lettuce (Lactuca sativa L.) and wild relatives: Vitamin C and anthocyanin content.Apr 19, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Chem. 2021 Apr 20 ;359:129864. Epub 2021 Apr 20. PMID: 33962194
Article Published Date : Apr 19, 2021
Study Type : Plant Study
Additional Links
Substances : Anthocyanins, Lettuce, Vitamin C, Wild Lettuce
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Plants grown under 20% blue and 80% red had the highest accumulations of the following seven elements Ca, Mg, Na, Fe, Mn, Zn and B.Apr 30, 2014

Pubmed Data : Guang Pu Xue Yu Guang Pu Fen Xi. 2014 May ;34(5):1394-7. PMID: 25095445
Article Published Date : Apr 30, 2014
Study Type : Plant Study
Additional Links
Substances : Lettuce
Additional Keywords : Growing Your Own Food, Light-Emitting Diodes (LEDs)
[+]

Quercetin, green tea extract and grape seed extract acted synergistically in combination with lettuce extract against oxidation of peroxidating liposomes.Dec 31, 2015

Pubmed Data : Food Chem. 2016 Jan 1 ;190:25-32. Epub 2015 May 16. PMID: 26212937
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Grape Seed Extract, Green Tea, Lettuce, Polyphenols, Quercetin
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Natural Substance Synergy
[+]

This studies results showed the anti-inflammatory and antioxidant potential of Maravilla de Verano polyphenolic extracts.Jan 17, 2016

Pubmed Data : J Sci Food Agric. 2016 Jan 18. Epub 2016 Jan 18. PMID: 26777118
Article Published Date : Jan 17, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lettuce
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Plant Extracts

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