Lupeol

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38 Diseases Researched for Lupeol

Name	AC	CK
Diabetic Complications	3	5
Hyperglycemia	3	5
Lipopolysaccharide-Induced Toxicity	2	4
Colorectal Cancer	3	3
Leishmaniasis	2	3
Lung Cancer	3	3
Wound Healing	2	3
Alzheimer's Disease	1	2
Arthritis	1	2
Brain Inflammation	1	2
Cancers: All	2	2
Cerebral Ischemia	1	2
Cholangiocarcinoma	1	2
Diabetes Mellitus: Type 2	1	2
Gastric Cancer	1	2
Head and Neck Cancer	1	2
Hypercholesterolemia	1	2
Inflammation	2	2
Liver Cancer	2	2
Lymph node carcinoma of the prostate (LNCaP)	1	2
Parkinson's Disease	1	2
Prostate Cancer	1	2
Skin Cancer: Prevention	1	2
Aging Skin	1	1
Cancer Metastasis	1	1
Cancers: Drug Resistant	1	1
Cervical Cancer	1	1
Kidney Cancer	1	1
Leukemia	1	1
Liver Damage	1	1
Malaria	1	1
Methicillin-resistant Staphylococcus aureus	1	1
Non-Small-Cell Lung Carcinoma	1	1
Oral Cancer	1	1
Osteosarcoma	1	1
Pesticide Toxicity	1	1
Squamous cell carcinoma	1	1
Ultraviolet Radiation Induced Damage	1	1

42 Pharmacological Actions Researched for Lupeol

Name	AC	CK
Apoptotic	9	11
Antiproliferative	8	10
Anti-Inflammatory Agents	6	9
Tumor Necrosis Factor (TNF) Alpha Inhibitor	3	6
Hypoglycemic Agents	3	5
NF-kappaB Inhibitor	4	5
Antioxidants	2	4
Immunomodulatory	3	4
Interleukin-6 Downregulation	2	4
Neuroprotective Agents	2	4
Anti-metastatic	3	3
Chemosensitizer	2	3
Cyclooxygenase 2 Inhibitors	2	3
Angiogenesis Inhibitors	1	2
Anticarcinogenic Agents	1	2
Antiparasitic Agents	1	2
Bcl-2 protein down-regulation	1	2
Cell cycle arrest	2	2
Chemopreventive	1	2
Hypolipidemic	1	2
Interleukin-1 beta downregulation	1	2
Interleukin-10 upregulation	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	2	2
Nrf2 activation	1	2
Survivin Down-Regulation	1	2
Tumor Suppressor Protein p53 Upregulation	1	2
Alpha-amylase inhibitor	1	1
Alpha-glucosidase inhibitor	1	1
Anti-Apoptotic	1	1
Anti-Bacterial Agents	1	1
Antimalarials	1	1
Cardioprotective	1	1
Cytoprotective	1	1
Epidermal growth factor receptor (EGFR) inhibitor	1	1
Genoprotective	1	1
Hepatoprotective	1	1
Leishmanicidal	1	1
Matrix metalloproteinase-1 (MMP-1) inhibitor	1	1
Matrix metalloproteinase-3 (MMP-3) inhibitor	1	1
Matrix metalloproteinase-9 (MMP-9) inhibitor	1	1
STAT3 Inhibitor	1	1
Wnt/β-catenin signaling pathway modulation	1	1

Research Articles 35
Cumulative Knowledge Score 56
Overall Research Rating GOOD

View the Evidence:
35 Abstracts with Lupeol Research

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View the Evidence: 35 Abstracts with Lupeol Research

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Lupeol acetate significantly improves the symptoms of RA by down-regulating expressions of inflammatory cytokines and osteoclastogenesis.Mar 31, 2016

Lupeol and mango extract induces programmed cell death in mouse prostate and lymph node carcinoma of the prostate. Jan 01, 2008

Lupeol and stigmasterol suppress tumor angiogenesis and inhibit cholangiocarcinoma growth.Dec 31, 2016

Lupeol enhances inhibitory effect of 5-fluorouracil on human gastric carcinoma cells.Apr 30, 2016

Lupeol enhances wound healing in streptozotocin-induced hyperglycaemia.Dec 31, 2018

Lupeol induces immunity and protective efficacy in a murine model against visceral leishmaniasis.Aug 31, 2019

Lupeol inhibits LPS-induced neuroinflammation in cerebellar cultures and induces neuroprotection.Apr 30, 2019

Lupeol may orchestrate a bifurcated regulation of neoplastic growth and apoptosis in head and neck cancers.Mar 31, 2017

Results of the study affirmed the antidiabetic activities of lupeol and iso-orientin.Dec 31, 2018

The combination of pterostilbene and lupeol was more effective in prevention of skin cancer as compared to either of the phytochemical alone.Dec 31, 2016

The data suggest that lupeol may exert protective effects against cerebral ischemia.May 31, 2020

Umbelliferone and Lupeol could be potential antidiabetic herbal remedies in the management of diabetes and its associated complications.Dec 31, 2015

Anti-metastatic effects of lupeol via the inhibition of MAPK/ERK pathway in lung cancer.Apr 23, 2020

Antileishmanial and immunomodulatory activities of lupeol.Sep 30, 2017

Antileukemic cell proliferation of active compounds from kaffir lime.Mar 11, 2020

Geraniol and lupeol inhibit growth and promote apoptosis in human hepatocarcinoma cells.Mar 31, 2019

Lupeol against high-glucose-induced apoptosis via enhancing the anti-oxidative stress in rabbit nucleus pulposus cells.Jul 13, 2018

Lupeol can be used in anti-metastasis of human osteosarcoma cells.Aug 31, 2019

Lupeol could be used as a potent anti-oxidant regimen against pesticide induced genotoxicity in agricultural farm workers.Jun 14, 2016

Lupeol has potential to be an effective agent against renal cell carcinoma with the modulation of mitochondrial dynamics.Jul 31, 2019

Lupeol induces S-phase arrest and mitochondria-mediated apoptosis in cervical cancer cells.May 31, 2018

Lupeol inhibits growth and migration in two human colorectal cancer cell lines by suppression of Wnt-β-catenin pathway.Dec 31, 2017

Lupeol inhibits human hepatocellular carcinoma cells.Jan 01, 2011

Lupeol inhibits migration and invasion of colorectal cancer cells.Feb 05, 2020

Lupeol is one of active compounds in the CH2Cl2 fraction of Chrysanthemum indicum that inhibits LMP1-induced NF-κB activation.Dec 31, 2012

Lupeol may act as a potent inhibitor of the EGFR signalling in oral squamous cell carcinoma.May 31, 2016

Lupeol may be useful as an anti-aging agent.Feb 28, 2019

Lupeol served as a strong chemoresistant sensitizer and could be a new adjuvant therapy method for chemoresistant patients.Apr 30, 2018

Lupeol suppresses plasminogen activator inhibitor-1-mediated macrophage recruitment and attenuates M2 macrophage polarization.Jul 04, 2020

Lupeol triterpene exhibits potent antitumor effects in A427 human lung carcinoma cells.Apr 30, 2018

Suppression of EGFR/STAT3 activity by lupeol contributes to the induction of the apoptosis of human non‑small cell lung cancer cells.Jun 30, 2019

These findings suggest that lupeol has therapeutic potential for accelerating wound healing.Oct 29, 2018

This review suggests that lupeol might be a valuable anti-inflammatory, anti-diabetic, hepatoprotective and anticancer treatment.Dec 31, 2015

This study further confirms the traditional role of Ficus benjamina plant in the treatment of malaria which may be attributed to ursolic acid and lupeol.Jan 01, 2019

This study highlights the potential of both stigmasterol and lupeol as new promising anti-MRSA agents.Dec 08, 2016

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Lupeol

View the Evidence:
35 Abstracts with Lupeol Research