Luteolin

Name	AC	CK
Coronavirus Infection	15	62
Inflammation	27	44
Smell Disorders	3	41
Oxidative Stress	21	37
Lipopolysaccharide-Induced Toxicity	20	35
Brain Inflammation	16	33
Myocardial Ischemia	4	27
Coronavirus Disease (Covid-19)	7	25
Alzheimer's Disease	13	21
Lung Cancer	15	19
Depression	9	17
Cancers: All	16	16
Nonalcoholic fatty liver disease (NAFLD)	4	16
Breast Cancer	12	15
Cardiovascular Diseases	5	15
Memory Disorders	4	15
Autism Spectrum Disorders	3	14
Colorectal Cancer	11	13
Liver Cancer	9	13
Breast Cancer: Triple Negative	8	12
Colon Cancer	10	12
Metabolic Syndrome X	2	12
Aging Skin	2	11
Athletic Performance	1	10
Cancers: Drug Resistant	8	10
Fatigue	1	10
Gulf War Syndrome	1	10
Sepsis	5	10
Escherichia coli Infections	4	9
Insulin Resistance	5	9
Ischemia	3	9
Obesity	5	9
Chemically-Induced Liver Damage	4	8
Diabetic Complications	3	8
Gastric Cancer	7	8
Hyperglycemia	3	8
Ovarian Cancer	6	8
Prostate Cancer	5	8
Neurodegenerative Diseases	6	7
Cancer Metastasis	5	6
Carcinoma: Non-Small-Cell Lung	5	6
Glioblastoma	6	6
Kidney Damage: Chemically-Induced	3	6
Lead Poisoning	3	6
Lung Damage	3	6
Parkinson's Disease	4	6
Urinary Tract Infections	2	6
Cadmium Poisoning	3	5
Chemotherapy-Induced Toxicity: Cisplatin	3	5
Cognitive Decline/Dysfunction	3	5
Endothelial Dysfunction	4	5
Esophageal Cancer	4	5
Hypercholesterolemia	3	5
Melanoma	3	5
Multiple Sclerosis	3	5
Staphylococcus aureus infection	4	5
Anxiety	2	4
Anxiety Disorders	2	4
Atherosclerosis	2	4
Bisphenol Toxicity	2	4
Cervical Cancer	2	4
Colitis	2	4
Diabetes: Cardiovascular Illness	2	4
Diabetic Nephropathy	3	4
Endometritis	2	4
Fibrosis	2	4
Fluoride Toxicity	2	4
Hepatic Steatosis	2	4
Hypertension	2	4
Learning disorders	2	4
Liver Cirrhosis	2	4
Liver Fibrosis	2	4
Lung Injury: Acute	2	4
Osteoporosis	2	4
Spinal Cord Injuries	2	4
Testicular Injury: Chemical/Metal Induced	2	4
Acute Respiratory Distress Syndrome	1	3
Allergic Rhinitis	2	3
Brain Ischemia	2	3
Brain: Microglial Activation	3	3
Cerebral Ischemia	2	3
Chemotherapy-Induced Toxicity: Doxorubicin	2	3
Diabetes Mellitus: Type 2	3	3
Glioma	3	3
Hashimoto's thyroiditis	2	3
Hypoxia	2	3
Lupus Nephritis	1	3
Osteoarthritis	2	3
Periodontal Diseases	2	3
Tumors	3	3
Ultraviolet Radiation Induced Damage	2	3
Wound Healing	2	3
Acetaminophen (Tylenol) Toxicity	1	2
Advanced Glycation End products (AGE)	2	2
Animal Diseases: Infectious	1	2
Arthritis	1	2
Autism	1	2
Blue Light Toxicity	1	2
Brain: Oxidative Stress	1	2
Cancer: Pain	1	2
Cardiomyopathy	1	2
Cerebral Hypoperfusion	1	2
Chemotherapy-Induced Toxicity: Gentamicin	1	2
Chemotherapy-Induced Toxicity: Irinotecan	1	2
Chemotherapy-Induced Toxicity: Tamoxifen	1	2
Chikungunya Virus	2	2
Chronic Pain	1	2
Constipation	1	2
Diabetes Mellitus: Type 1	1	2
Diabetes: Cognitive Dysfunction	1	2
Down Syndrome	1	2
Drug-Induced Toxicity: Gastrointestinal	1	2
Dyslipidemias	1	2
Electromagnetic Radiation Mitigation	1	2
Endometriosis	1	2
Enterovirus 71	1	2
Epilepsy	1	2
Graves Disease	1	2
Heart Failure	1	2
Hepatoma	2	2
High Fat Diet	1	2
Hydrogen Peroxide Induced Toxicity	2	2
Hyperlipidemia	1	2
Hypertension: Pulmonary	1	2
Intracerebral Hemorrhage	1	2
Kidney Cancer	1	2
Kidney Damage	1	2
Liver Damage	1	2
Liver Failure: Acute	1	2
Lung Cancer: Prevention	1	2
Mercury Poisoning	1	2
Methicillin-resistant Staphylococcus aureus	1	2
Mood Disorders	1	2
Mucositis	1	2
Neurodevelopmental Disorders	1	2
Pancreatic Cancer	2	2
Photooxidative Stress	1	2
Pneumonia	1	2
Polycystic Ovary Syndrome	1	2
Post-Traumatic Stress Disorders (PTSD)	1	2
Postmenopausal Disorders: Weight Gain/Obesity	1	2
Prenatal Nutrition: Health of the Offspring	1	2
Promyelocytic leukemia	2	2
Respiratory Distress Syndrome	1	2
Sarcopenia	1	2
Sleep Disorders	1	2
Subarachnoid hemorrhage	1	2
Ulcerative Colitis	1	2
Adiponectin: Low Levels	1	1
Air Pollution Linked Toxicity	1	1
Allergies	1	1
Bladder Cancer	1	1
Breast Cancer: Lung Metastasis	1	1
Cancers: Canine	1	1
Candida Albicans	1	1
Cardiac Hypertrophy	1	1
Central Nervous System Diseases	1	1
Chemotherapy-Induced Toxicity: Cyclophosphamide	1	1
Chemotherapy-Induced Toxicity: 5-fluorouracil	1	1
Cholesterol: Oxidation	1	1
Choriocarcinoma	1	1
Chronic Lymphocytic Leukemia	1	1
Chronic Obstructive Pulmonary Disease	1	1
Cystitis	1	1
Ehrlich carcinoma	1	1
Endothelial Damage	1	1
Enterococcus Infections	1	1
Excitotoxicity	1	1
Eye Damage	1	1
Gastrointestinal Inflammation	1	1
Gout	1	1
HIV Infections	1	1
Heavy Metal Toxicity	1	1
Hyperinsulinism	1	1
Hyperuricemia	1	1
Inflammatory Bowel Diseases	1	1
Influenza A	1	1
Keloid	1	1
Klebsiella Infections	1	1
Laryngeal Cancer	1	1
Leishmaniasis	1	1
Leukemia	1	1
Lipid Peroxidation	1	1
Lipotoxicity	1	1
Listeria Infections	1	1
Lyme Borreliosis	1	1
Lyme Disease	1	1
Macular Degeneration	1	1
Mitochondrial Dysfunction	1	1
Multiple Myeloma	1	1
Non-Small-Cell Lung Carcinoma	1	1
Osteosarcoma	1	1
Pseudomonas aeruginosa	1	1
Psoriasis	1	1
Rheumatoid Arthritis	1	1
Severe Acute Respiratory Syndrome	1	1
Squamous cell carcinoma	1	1
Staphylococcus aureus: Methicillin-resistant (MRSA)	1	1
Thyroid Cancer	1	1
Tongue Cancer	1	1
Vaccination: Coronavirus	1	1
Weight Problems	1	1

Name	AC	CK
Anti-Inflammatory Agents	104	213
Antioxidants	69	148
Apoptotic	73	89
Neuroprotective Agents	47	89
Antiproliferative	63	73
Cardioprotective	22	66
Interleukin-6 Downregulation	37	62
Nrf2 activation	29	53
Anti-Apoptotic	17	45
Tumor Necrosis Factor (TNF) Alpha Inhibitor	25	44
NF-kappaB Inhibitor	22	38
Anti-metastatic	27	37
Hepatoprotective	13	37
Interleukin-1 beta downregulation	22	35
Malondialdehyde Down-regulation	7	32
Antidepressive Agents	10	27
Renoprotective	10	19
Antiviral Agents	15	17
Anti-Anxiety Agents	3	14
Antineoplastic Agents	10	14
Autophagy Up-regulation	7	14
Cell cycle arrest	13	14
Chemoprotective Agents	8	14
Matrix metalloproteinase-9 (MMP-9) inhibitor	9	14
Heme oxygenase-1 up-regulation	8	13
MicroRNA modulator	10	13
Matrix metalloproteinase-2 (MMP-2) inhibitor	8	12
Anti-Bacterial Agents	6	11
Chemosensitizer	10	11
Chemotherapeutic	10	11
Chemopreventive	8	10
Anti-Fibrotic	4	8
Cyclooxygenase 2 Inhibitors	7	8
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	5	8
Immunomodulatory	7	8
Superoxide Dismutase Up-regulation	5	8
Angiogenesis Inhibitors	6	7
Gastrointestinal Agents	4	7
Interleukin-10 upregulation	4	7
Osteoprotective	3	7
STAT3 Inhibitor	5	7
Anticarcinogenic Agents	4	6
Antihypertensive Agents	3	6
Neurogenesis	3	6
Tumor Suppressor Protein p53 Upregulation	5	6
Wnt/β-catenin signaling pathway modulation	5	6
Enzyme Inhibitors	5	5
Hypoglycemic Agents	4	5
Autophagy Inhibitors	3	4
Brain-derived neurotrophic factor modulator	2	4
Gastroprotective	2	4
Hypolipidemic	2	4
Interleukin-8 downregulation	4	4
P21 Activation	3	4
Radioprotective	2	4
Anti-Allergic Agents	3	3
Anticholesteremic Agents	2	3
Antimicrobial	3	3
Cytoprotective	2	3
Interferon Gamma Reducer	2	3
Interleukin-17 downregulation	2	3
Nitric Oxide Inhibitor	2	3
Photoprotective	2	3
Vascular Endothelial Growth Factor Inhibitors	3	3
anti-inflammatory	2	3
12-lipoxygenase (12-LOX) Inhibitor	1	2
Alpha-glucosidase inhibitor	2	2
Anticonvulsants	1	2
Antinoceceptive	1	2
Anxiolytic	1	2
Bcl-2 protein down-regulation	2	2
C-Jun N-Terminal Kinases (JNK) Modulator	1	2
Chemokine (C-C motif) Ligand 2 (CCL2) Down-Regulation	1	2
Cyclin D1 Down-Regulation	1	2
Epidermal growth factor receptor (EGFR) inhibitor	1	2
Hypnotics and Sedatives	1	2
Hypoxia-inducible factor-1 (HIF-1) inhibitor	2	2
Immunosuppressive Agents	1	2
Insulin Sensitizers	1	2
Interleukin-2 Downregulation	1	2
Interleukin-23 Downregulation	1	2
Interleukin-4 downregulation	1	2
Interleukin-4 upregulation	1	2
Matrix metalloproteinase-8 (MMP-8) inhibitor	1	2
Pancreato Protective Agents	1	2
Proteasome Inhibitors	2	2
Radiosensitizer	2	2
Regenerative	1	2
Uricosuric Agents	1	2
Vascular Endothelial Growth Factor A Inhibitor	2	2
Angiogenesis Inducing Agents	1	1
Anti-Angiogenic	1	1
Anti-Glycation Agents	1	1
Cytotoxicity	1	1
Heat Shock Protein Down-Regulation	1	1
Immunostimulatory	1	1
Interferon Inducers	1	1
Interleukin-18 down-regulation	1	1
Interleukin-22 Downregulation	1	1
Multidrug Resistance Gene Modulators	1	1
Neuritogenic	1	1
Telomerase Inhibitor	1	1
Transforming growth factor beta (TGF-β) inhibitor	1	1
Vascular Endothelial Growth Factor Regulator	1	1
Vasodilator Agents	1	1
Wnt/β-catenin pathway down-regulation	1	1
Xanthine oxidase inhibitor	1	1

[+]

Cardioprotective effects and possible mechanisms of luteolin for myocardial ischemia-reperfusion injury.Dec 31, 2021

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Pubmed Data : Nutrients. 2019 Feb 6 ;11(2). Epub 2019 Feb 6. PMID: 30736383

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Pubmed Data : Oxid Med Cell Longev. 2016 ;2016:4389410. Epub 2016 Jan 19. PMID: 26904164

Article Published Date : Dec 31, 2015

Study Type : Human Study

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Substances : Coenzyme Q10, Grape, Luteolin, Selenium

Diseases : Aging Skin

Pharmacological Actions : Antioxidants

[+]

Supplementation with PEALUT helped to improve all patient-reported symptoms, especially pain, anxiety and depression, fatigue, brain fog, anosmia and dysgeusia.Aug 23, 2023

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Pubmed Data : Nutrients. 2023 Aug 24 ;15(17). Epub 2023 Aug 24. PMID: 37686733

Luteolin rescues postmenopausal osteoporosis.May 31, 2024

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Pubmed Data : Phytomedicine. 2024 Jun ;128:155516. Epub 2024 Mar 16. PMID: 38547625

Article Published Date : May 31, 2024

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Pubmed Data : Cancers (Basel). 2023 Jan 16 ;15(2). Epub 2023 Jan 16. PMID: 36672499

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Pubmed Data : Int Immunopharmacol. 2019 Jan 11 ;68:171-178. Epub 2019 Jan 11. PMID: 30641432

Article Published Date : Jan 10, 2019

Study Type : Animal Study

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Substances : Apigenin, Chrysin, Luteolin

Diseases : Liver Failure: Acute

Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Hepatoprotective, Malondialdehyde Down-regulation, Nrf2 activation, Superoxide Dismutase Up-regulation

[+]

Co-ultramicronized palmitoylethanolamide and luteolin promotes neuronal regeneration after spinal cord injury.Dec 31, 2015

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Pubmed Data : Front Pharmacol. 2016 ;7:47. Epub 2016 Mar 8. PMID: 27014061

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Luteolin, Palmitoylethanolamide

Diseases : Spinal Cord Injuries

Pharmacological Actions : Neuroprotective Agents, Regenerative

Additional Keywords : regen

[+]

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Pubmed Data : Int Immunopharmacol. 2020 Jun 13 ;85:106680. Epub 2020 Jun 13. PMID: 32544871

Article Published Date : Jun 12, 2020

Study Type : Animal Study

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Substances : Luteolin

Diseases : Myocardial Ischemia

Pharmacological Actions : Cardioprotective

[+]

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Pubmed Data : Exp Clin Endocrinol Diabetes. 2020 Jan 2. Epub 2020 Jan 2. PMID: 31896157

Article Published Date : Jan 01, 2020

Study Type : Animal Study

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Substances : Luteolin

Diseases : Diabetic Nephropathy, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, STAT3 Inhibitor

[+]

Luteolin attenuates doxorubicin-induced cardiotoxicity.Dec 31, 2019

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Pubmed Data : Antioxidants (Basel). 2019 Dec 21 ;9(1). Epub 2019 Dec 21. PMID: 31877779

Article Published Date : Dec 20, 2019

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Chemically-Induced Liver Damage, Lead Poisoning

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Hepatoprotective

Problem Substances : Lead

[+]

Luteolin could reduce inflammatory damage to cardiomyocytes induced by LPS by down-regulating Nlrp3.Feb 28, 2022

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Pubmed Data : Yonsei Med J. 2022 Mar ;63(3):220-228. PMID: 35184424

Article Published Date : Feb 28, 2022

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants

[+]

Luteolin could restore sensitivity of oxaliplatin resistant cell lines to chemotherapeutic drugs.Dec 31, 2013

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Pubmed Data : J Food Biochem. 2020 Jun 29:e13358. Epub 2020 Jun 29. PMID: 32598492

Article Published Date : Jun 28, 2020

Study Type : Animal Study

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Substances : Luteolin

Diseases : Hypercholesterolemia, Obesity

Pharmacological Actions : Anticholesteremic Agents, Hypoglycemic Agents

[+]

Luteolin induces hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome.Mar 31, 2019

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[+]

Luteolin may be a potential candidate for NSCLC therapy, especially for treatment of patients with acquired erlotinib-resistant NSCLC.May 31, 2014

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Pubmed Data : Br J Pharmacol. 2014 Jun ;171(11):2842-53. PMID: 24471765

Article Published Date : May 31, 2014

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Cancers: Drug Resistant, Carcinoma: Non-Small-Cell Lung, Lung Cancer

Pharmacological Actions : Antineoplastic Agents, Apoptotic, Epidermal growth factor receptor (EGFR) inhibitor

Additional Keywords : Chemotherapeutic Synergy: Erlotinib

[+]

Luteolin may be a promising lead for the treatment of drug-induced gastroenteropathy.Aug 04, 2020

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Pubmed Data : Drug Chem Toxicol. 2020 Aug 5:1-13. Epub 2020 Aug 5. PMID: 32757682

Article Published Date : Aug 04, 2020

Study Type : Animal Study

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Pubmed Data : IUBMB Life. 2019 Sep ;71(9):1401-1408. Epub 2019 Jun 11. PMID: 31185137

Article Published Date : Aug 31, 2019

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Multiple Sclerosis

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents

[+]

Luteolin may represent a promising candidate for the treatment of intracerebral hemorrhage-induced secondary brain injury.Dec 31, 2018

Pubmed Data : Eur J Pharmacol. 2021 Jul 12 ;908:174337. Epub 2021 Jul 12. PMID: 34265292

Article Published Date : Jul 11, 2021

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Chemotherapy-Induced Toxicity: Tamoxifen

Pharmacological Actions : Chemoprotective Agents, Hepatoprotective, Neuroprotective Agents

[+]

Luteolin modulates neural stem cells fate determination.Dec 31, 2020

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Pubmed Data : Antioxidants (Basel). 2022 Mar 24 ;11(4). Epub 2022 Mar 24. PMID: 35453311

Article Published Date : Mar 23, 2022

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Colorectal Cancer

Pharmacological Actions : Antiproliferative

Additional Keywords : Chemotherapeutic Synergy: Oxaliplatin

[+]

Luteolin treatment ameliorates brain development and behavioral performance in a mouse model of CDKL5 deficiency disorder.Aug 04, 2022

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Pubmed Data : Int J Mol Sci. 2022 Aug 5 ;23(15). Epub 2022 Aug 5. PMID: 35955854

Article Published Date : Aug 04, 2022

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Neurodevelopmental Disorders

Pharmacological Actions : Anti-Inflammatory Agents, Neurogenesis

[+]

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Pubmed Data : Phytomedicine. 2018 Oct 22 ;57:18-29. Epub 2018 Oct 22. PMID: 30668319

Article Published Date : Oct 21, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Liver Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, MicroRNA modulator

[+]

Modulatory effect of luteolin on redox homeostasis and inflammatory cytokines in a mouse model of liver cancer.Nov 30, 2016

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Pubmed Data : Brain Res. 2020 Oct 1 ;1744:146919. Epub 2020 May 30. PMID: 32485174

Article Published Date : Sep 30, 2020

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Electromagnetic Radiation Mitigation

Pharmacological Actions : Antioxidants, Neuroprotective Agents, Radioprotective

Anti Therapeutic Actions : Electromagnetic Radiation

[+]

Neuroprotective role of luteolin against lead acetate-induced cortical damage.Mar 24, 2020

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Pubmed Data : Hum Exp Toxicol. 2020 Mar 25:960327120913094. Epub 2020 Mar 25. PMID: 32208856

Protective effects of luteolin on nephrotoxicity induced by long-term hyperglycaemia.Mar 31, 2020

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Pubmed Data : Med Sci Monit. 2016 Dec 28 ;22:5173-5180. Epub 2016 Dec 28. PMID: 28029146

Article Published Date : Dec 27, 2016

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor, Renoprotective

[+]

Structure-based drug designing for potential antiviral activity of selected natural products from Ayurveda against SARS-CoV-2 spike glycoprotein and its cellular receptor.May 31, 2020

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Pubmed Data : Viruses. 2020 02 29 ;12(3). Epub 2020 Feb 29. PMID: 32121393

Article Published Date : Jan 28, 2020

Study Type : Review

Additional Links

Substances : Apigenin, Berberine, Chrysin, EGCG (Epigallocatechin gallate), Fisetin, Luteolin, Naringenin , Silibinin, Silymarin, Tannic Acid

Diseases : Chikungunya Virus

Pharmacological Actions : Antiviral Agents

[+]

Apigenin and luteolin are potent inhibitors of human thyroid cancer cell lines. Apr 01, 1999

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Pubmed Data : Thyroid. 1999 Apr;9(4):369-76. PMID: 10319943

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Pubmed Data : J Biol Regul Homeost Agents. 2021 06 8 ;35(3). Epub 2021 Jun 8. PMID: 34100279

Co-ultramicronized palmitoylethanolamide/luteolin restores oligodendrocyte homeostasis.May 25, 2022

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Pubmed Data : Cell Death Dis. 2019 Mar 4 ;10(3):218. Epub 2019 Mar 4. PMID: 30833546

Article Published Date : Mar 03, 2019

Study Type : In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Chemotherapeutic

[+]

Differential effects of luteolin and its glycosides on invasion and apoptosis in MDA-MB-231 triple-negative breast cancer cells.Dec 31, 2018

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Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Renoprotective, Transforming growth factor beta (TGF-β) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

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Pubmed Data : Med Oncol. 2021 May 5 ;38(6):66. Epub 2021 May 5. PMID: 33950369

Article Published Date : May 04, 2021

Study Type : Review

Additional Links

Substances : Luteolin

Diseases : Cancer Metastasis, Cancers: Drug Resistant

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic

[+]

Luteolin and chicoric acid, two abundant constituents of the common dandelion inhibit lipopolysaccharide-induced toxicity. Apr 15, 2011

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Pubmed Data : Eur J Pharmacol. 2011 Apr 15. Epub 2011 Apr 15. PMID: 21513709

Article Published Date : Apr 15, 2011

Study Type : In Vitro Study

Additional Links

Substances : Chicoric Acid, Dandelion , Luteolin

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor

[+]

Luteolin and kaempferol are a good candidate for the complementary therapeutic agent against liver cancer.Apr 30, 2018

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Pubmed Data : Mol Pharmacol. 2007 May;71(5):1381-8. Epub 2007 Feb 12. PMID: 17296806

Article Published Date : May 01, 2007

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Pubmed Data : J Cell Biochem. 2018 Aug 20. Epub 2018 Aug 20. PMID: 30129150

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Pubmed Data : J Cancer. 2018 ;9(20):3669-3675. Epub 2018 Sep 8. PMID: 30405835

Article Published Date : Dec 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Gastric Cancer

Pharmacological Actions : Antiproliferative , MicroRNA modulator, STAT3 Inhibitor

[+]

Luteolin exhibits anti-breast cancer property through up-regulating miR-203.Nov 30, 2019

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Pubmed Data : J Cell Physiol. 2018 Oct 26. Epub 2018 Oct 26. PMID: 30362587

Article Published Date : Oct 25, 2018

Study Type : In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Cancers: Canine

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Luteolin induces apoptosis by impairing mitochondrial function and targeting the intrinsic apoptosis pathway in gastric cancer cells.Jul 31, 2023

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Pubmed Data : Cytotechnology. 2010 Feb 17. Epub 2010 Feb 17. PMID: 20162352

Article Published Date : Feb 17, 2010

Study Type : In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Osteoporosis

[+]

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Pubmed Data : RNA Biol. 2018 Oct 26. Epub 2018 Oct 26. PMID: 30362859

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Pubmed Data : Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2018 Oct ;26(5):1425-1429. PMID: 30295262

Article Published Date : Sep 30, 2018

Study Type : In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Multiple Myeloma

Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Inhibitors

Additional Keywords : Dose Response

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Luteolin inhibits viral-induced inflammatory response in RAW264.7 cells Mar 22, 2016

Article Published Date : Jan 08, 2017

Study Type : In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Gastrointestinal Inflammation, Inflammatory Bowel Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-8 downregulation

[+]

Luteolin may be a promising treatment for PC and COVID-19 based on bioinformatics findings.Dec 31, 2020

Click here to read the entire abstract

Pubmed Data : Front Endocrinol (Lausanne). 2021 ;12:802447. Epub 2022 Feb 1. PMID: 35178029

Article Published Date : Dec 31, 2020

Study Type : In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Coronavirus Infection, Prostate Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Chemotherapeutic

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View the Evidence: 389 Abstracts with Luteolin Research

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Cardioprotective effects and possible mechanisms of luteolin for myocardial ischemia-reperfusion injury.Dec 31, 2021

Efficacy of palmitoylethanolamide and luteolin association on post-covid olfactory dysfunction.Aug 02, 2023

Altilix supplementation was a beneficial approach in the management of hepatic and cardiometabolic alterations in metabolic syndrome subjects.Oct 24, 2019

An open-label pilot study of a formulation containing the anti-inflammatory flavonoid luteolin and its effects on behavior in children with autism spectrum disorders.Apr 30, 2013

Co-ultramicronized palmitoylethanolamide/luteolin normalizes GABAB-ergic activity and cortical plasticity in long COVID-19 syndrome.Dec 31, 2022

Effect of ultra-micronized palmitoylethanolamide and luteolin on olfaction and memory in patients with long covid.Aug 16, 2022

Enhancement of exercise performance by 48 hours, and 15-day supplementation with mangiferin and luteolin in men.Feb 05, 2019

Olfactory rehabilitation and Palmitoylethanolamide +Luteolin oral supplement might prevent SARS-CoV-2 associated olfactory impairment.Dec 31, 2020

resveratrol may be beneficial in reducing symptoms of Gulf War Illness.Mar 02, 2021

Skin Antiageing and Systemic Redox Effects of Supplementation with marine collagen peptides and plant-derived antioxidants.Dec 31, 2015

Supplementation with PEALUT helped to improve all patient-reported symptoms, especially pain, anxiety and depression, fatigue, brain fog, anosmia and dysgeusia.Aug 23, 2023

Treatment of COVID-19 olfactory dysfunction with olfactory training, palmitoylethanolamide with luteolin.Oct 31, 2023

Apigenin and Luteolin significantly activate the PI3K/Nrf2/ARE system, and this activation may be responsible for their anti-inflammatory effects.Apr 21, 2015

Combination treatments with luteolin and fisetin may be a potential candidate for the treatment and prevention of diabetes and its complications.Jun 25, 2017

Luteolin and apigenin derived glycosides from Alphonsea elliptica abrogate LPS-induced inflammatory responses in human plasma.Apr 19, 2021

Luteolin decreased the attachment and invasion of uropathogenic escherichia coli in bladder epithelial cells, attenuated UPEC-induced cytotoxicity and biofilm formation.Sep 30, 2014

Luteolin prevents angiotensin II-induced cardiac remodeling.Jan 01, 2015

Protective effect of luteolin on skin ischemia-reperfusion injury through an AKT-dependent mechanism.Oct 01, 2018

Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress.Jan 31, 2022

Luteolin attenuates lupus nephritis by regulating macrophage oxidative stress via HIF-1α pathway.Aug 14, 2023

Luteolin induces ferroptosis in prostate cancer cells.Oct 29, 2023

Luteolin inhibits triple-negative breast cancer by inducing apoptosis and autophagy.Dec 31, 2022

Luteolin rescues postmenopausal osteoporosis.May 31, 2024

Palmitoylethanolamide and luteolin in combination could have beneficial effects in autism.Dec 31, 2016

Protective effects and mechanisms of luteolin against acute respiratory distress syndrome.Apr 07, 2024

Synergistic combination of luteolin and asiatic acid on cervical cancer. Jan 15, 2023

Ameliorative effects of luteolin against endometriosis progression.Mar 02, 2019

Antiviral efficacy of flavonoids against enterovirus 71 infection.Jul 06, 2019

Anxiolytic effects of the flavonoid luteolin in a mouse model of acute colitisDec 25, 2019

Apigenin has good hepatoprotective effects and potential as a promising therapeutic agent for acute liver failure in clinical application.Jan 10, 2019

Co-ultramicronized palmitoylethanolamide and luteolin promotes neuronal regeneration after spinal cord injury.Dec 31, 2015

Combination of curcumin and luteolin synergistically inhibits TNF-α-induced vascular inflammation in human vascular cells and mice.Aug 14, 2019

Combination of luteolin and lycopene effectively protect against nonalcoholic fatty liver disease.Jun 19, 2020

Combined curcumin and luteolin synergistically inhibit colon cancer.Jun 17, 2022

Cynaroside improved depressive-like behavior in CUMS mice by suppressing microglial inflammation and ferroptosis.Mar 31, 2024

Cynaroside protects the blue light-induced retinal degeneration through alleviating apoptosis and inducing autophagy in vitro and in vivo.Jul 14, 2021

Dietary luteolin protects against mercuric chloride induced renal injury.Nov 08, 2017

Effects of verbascoside and luteolin on oxidative damage in brain of heroin treated mice.Jun 30, 2005

Flavonoids could be used as protective agents against oxidative stress induced by gentamicin.Jul 31, 2018

Flavonoids may act as a prenatal preventive against increased interleukin-6 mediated maternal immune activiation associated with abnormal social interactions in adult offspring. Dec 10, 2009

Long-term supplementation with a luteolin enriched artichoke leaf extract can prevent adiposity and related metabolic disorders.Jul 26, 2018

Lonicera japonica Thunb extract ameliorates lipopolysaccharide-induced acute lung injury.Dec 18, 2023

Low dose of luteolin activates Nrf2 in the liver of mice.Dec 31, 2019

Luteolin activates Tregs to promote IL-10 expression and alleviating caspase-11-dependent pyroptosis in sepsis-induced lung injury.Jul 07, 2021

Luteolin alleviates cadmium-induced kidney injury.Apr 25, 2024

Luteolin alleviates cadmium-induced metabolism disorder through antioxidant and anti-inflammatory mechanisms.Apr 30, 2024

Luteolin alleviates cognitive impairment in Alzheimer's disease model.Jul 14, 2021

Luteolin alleviates inflammation and autophagy of hippocampus induced by cerebral ischemia/reperfusion.Jun 30, 2022

Luteolin alleviates inflammation and modulates gut microbiota in ulcerative colitis rats.Mar 14, 2021

Luteolin alleviates ischemia/reperfusion injury-induced no-reflow by regulating Wnt/β-catenin signaling.Oct 20, 2021

Luteolin alleviates liver fibrosis in rat hepatic stellate Cell HSC-T6.Dec 31, 2022

Luteolin alleviates LPS-induced bronchopneumonia injury in vitro and in vivoJul 29, 2018

Luteolin alleviates methionine-choline-deficient diet-induced non-alcoholic steatohepatitis.Dec 31, 2021

Luteolin alleviates myocardial ischemia reperfusion injury.Jun 12, 2020

Luteolin ameliorated the myocardium fibrosis of heart failure.Jan 22, 2017

Luteolin ameliorates depression-like behaviors by suppressing ER stress.Jan 14, 2022

Luteolin ameliorates diet-induced obesity and its comorbidities.Oct 02, 2018

Luteolin ameliorates experimental lung fibrosis both in vivo and in vitro.Nov 23, 2010

Luteolin ameliorates ferric nitrilotriacetic acid induced renal toxicity and tumor promotional response in rat.May 01, 2009

Luteolin ameliorates hypoxia-induced pulmonary hypertension.Aug 31, 2022

Luteolin ameliorates loperamide-induced functional constipation in mice.Dec 31, 2022

Luteolin ameliorates testis injury and blood-testis barrier disruption.Mar 28, 2019

Luteolin and 5-flurouracil act synergistically to induce cellular weapons in experimentally induced solid ehrlich carcinomaAug 31, 2019

Luteolin and exercise combination therapy ameliorates amyloid-β1-42 oligomers-induced cognitive impairment.Jan 24, 2023

Luteolin attenuates acute lung injury in experimental mouse model of sepsis.Apr 10, 2018

Luteolin attenuates allergic nasal inflammation.Dec 31, 2019

Luteolin attenuates cardiac ischemia/reperfusion injury in diabetic animals.Dec 31, 2018

Luteolin attenuates CCl4-induced hepatic injury by inhibiting ferroptosis.May 15, 2024

Luteolin attenuates cognitive dysfunction induced by chronic cerebral hypoperfusion.Aug 31, 2021

Luteolin attenuates diabetic nephropathy through suppressing inflammatory response and oxidative stress.Jan 01, 2020

Luteolin attenuates doxorubicin-induced cardiotoxicity.Dec 31, 2019

Luteolin attenuates hepatic injury in septic mice by regulating P2X7R-based HMGB1 release.Oct 31, 2021

Luteolin

View the Evidence:
389 Abstracts with Luteolin Research